Loratadine (Claritin) – Side Effects, Interactions, Uses, Dosage, Warnings

uses

What is Loratadine (Claritin) used for?

• Allergic Rhinitis
• Urticaria
• Allergic Urticaria
• Physical Urticaria

warnings

What is the most important information I should know about Loratadine (Claritin)?

You should not use this medicine if you are allergic to loratadine.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• kidney disease; or
• liver disease.

The disintegrating tablet may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to a child younger than 2 years old without medical advice.

User Reviews & Rating

Overall rating for Loratadine (Claritin)

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Read Loratadine (Claritin) Reviews

Side Effects

What are the side effects of Loratadine (Claritin)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

• headache; or
• feeling tired or drowsy.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Loratadine (Claritin) if I’m pregnant or breastfeeding?

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Interactions

What drugs and food should I avoid while taking Loratadine (Claritin)?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to take Loratadine (Claritin)?

Use Loratadine (Claritin) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Loratadine (Claritin)?

Loratadine is used when needed. Do not use this medicine more than once in a 24-hour period. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Loratadine (Claritin)?

If you think you or someone else may have overdosed on: Loratadine (Claritin),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Loratadine (Claritin), call 911

911

What to Expect

You should start to feel better within about an hour of taking loratadine.

Depending on your condition, you may only need to use this medicine for a short period of time, or you might need to take it longer to treat stubborn allergies.

Generally, it’s considered safe to use loratadine for a long time, but you should only take it if you need it.

Secondary Uses

Loratadine may be used for conditions not listed in this medical guide.

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Loratadine – StatPearls – NCBI Bookshelf

Continuing Education Activity

Loratadine is a medication used to manage and treat allergic rhinitis and urticaria. It is in the second generation antihistamine class. This activity reviews the indications, action, and contraindications for loratadine as a valuable agent in treating and managing allergic rhinitis and urticaria. This activity will highlight the mechanism of action, adverse effects, and other key factors such as dosing, pharmacodynamics, pharmacokinetics, monitoring, and relevant interactions pertinent for interprofessional team members in the treatment and care of patients with allergic rhinitis and related conditions.

Objectives:

• Identify the mechanism of action of loratadine.

• Describe the possible adverse effects of loratadine.

• Review appropriate monitoring of loratadine along with the signs of toxicity for this drug.

• Summarize interprofessional team strategies for improving care coordination and communication to advance loratadine and improve outcomes.

Access free multiple choice questions on this topic.

Indications

Loratadine is a piperidine histamine h2-receptor antagonist with anti-allergic properties but without sedative effects. The drug is an FDA-approved medication to relieve and treat allergic rhinitis (hay fever) and urticaria (allergic skin rash).[1][2][3] Loratadine is an effective, second-generation antihistamine with use in a variety of conditions such as relief of pruritus, watery eyes, runny nose, and sneezing associated with seasonal allergies.[4] Loratadine is available as a prescription by the patient’s clinician, but it is also available as an over-the-counter (OTC) medication as both a branded and generic product. Loratadine is safe to use in the geriatric population and children over the age of two.

The drug was involved in controversy as one of the first direct-to-consumer advertised drugs., leading to further FDA clarification on what must appear in drug advertising.[5] The drug was petitioned to be made available over-the-counter in 1998, which the FDA granted. In 2002, the original manufacturer made their product available OTC.[6]

Mechanism of Action

Loratadine is a long-acting, second-generation, non-sedating tricyclic antihistamine (piperidine derivative) with selective antagonistic properties to peripheral histamine h2-receptors. Loratadine selectively inhibits h2-receptors primarily located on respiratory smooth muscle cells, vascular endothelial cells, the gastrointestinal tract, and immune cells. Unlike the first-generation antihistamines such as diphenhydramine, loratadine is a competitive histamine antagonist that does not cross the blood-brain barrier. Therefore, it does not affect the neurons of the central nervous system, thereby preventing daytime somnolence or sedation.[7][8]

Loratadine binds to h2-receptors in different cells and causes a decrease in vascular permeability (prevents edema and flushing), decreases smooth muscle tone (bronchodilation), and decreases the activation of the peripheral nociceptive receptors (decreases pain and pruritus).  At high concentrations, second-generation antihistamines such as loratadine can inhibit histamine release from mast cells and basophils, thereby reducing ICAM-1 expression in epithelial cells and inhibiting type 1 hypersensitivity reactions (e.g., hay fever, urticaria, pruritus, edema).[9] There is also evidence of anti-inflammatory properties with second-generation antihistamines.[10]

Loratadine has a rapid onset of action; it works within 1 to 3 hours, its effects peak within 8 to 12 hours, and elimination occurs through the fecal and renal routes. It has a half-life of approximately 8 hours, and the half-life of its active metabolite is 28 hours. Metabolism is primarily in the liver into its active metabolite, descarboethoxy-loratadine, via the CYP450 pathway, specifically, CYP 3A4.

Administration

Loratadine dosing is by tablet (chewable or ODT – orally disintegrating tablet), liquid-filled capsule, or syrup (1 mg/mL solution). The medication can be administered orally with or without meals, although the recommendation is to take the oral medication on an empty stomach. The dispersible tablet is placed in the mouth and allowed to dissolve. The patient may swallow it with or without water. Research is underway for other formulations designed to increase bioavailability.[11]

For allergic rhinitis:

• In adolescents, adults, and geriatrics: 10 mg by mouth daily or 5 mg twice daily; do not exceed 10 mg in 24 hours.

• In pediatrics: age 2 to 5: 5 mg orally every day; over the age of 6: 10 mg orally daily. The ODT formulation is not recommended for younger children.

For urticaria:

• In adolescents, adults, and geriatrics: 10 mg by mouth daily: generally dosing should not exceed 10 mg in 24 hours. However, some patients may benefit from higher doses – clinicians should weigh the risk vs. benefit.

• In pediatrics over the age of 6: 10 mg by mouth daily as needed. 

In both renal and hepatic insufficiency, the recommendation is to increase the dosing interval to 48 hours, as follows:

Patients with renal impairment (GFR of less than 30 mL/min): 

• In adults: 10 mg orally every other day.

• In children age 2 to 6: 5 mg oral dosing every other day.

• In children over the age of 6: 10 mg by mouth every other day.

Patients on peritoneal or hemodialysis should be dosed every 48 hours; no supplemental dose following dialysis.

Patients with hepatic impairment:

• In adults: 10 mg orally every other day.

• In children aged 2 to 6: 5 mg orally every other day.

• In children over the age of 6: 10 mg by mouth every other day.

The drug’s half-life increases with the increasing severity of the hepatic disease.

Loratadine is subject to half-life variability in the elderly, and clinicians need to be mindful of this factor when initiating therapy in this age group.

Adverse Effects

Though loratadine is a relatively safe and effective medication for treating allergic rhinitis, its primary adverse effects include headaches, dizziness, and GI distress (diarrhea, abdominal pain, nausea, and vomiting). Loratadine may also cause sedation (rare side effect), mydriasis, and xerostomia. These effects are primarily due to the drug’s anticholinergic effects.[12][13] 

Patients should not take loratadine with other CNS depressants such as diphenhydramine, dextromethorphan, or pseudoephedrine as it may cause dose-related sedation. There is no evidence for increased adverse events when combining loratadine and oral contraceptives.

Contraindications

Contraindications to loratadine include patients with documented hypersensitivity to the drug or components of the formulation, with strong contraindications in children under the age of 2 due to its antihistamine properties, which may cause CNS stimulation or seizures in young patients.

This medication requires cautious use in asthmatic or COPD patients due to its anticholinergic effects, which may cause a flare-up.

Though the medication is generally non-sedating, patients who perform activities requiring concentration, such as driving a motor vehicle, should be advised to use caution as it may cause some drowsiness.

Patients diagnosed with phenylketonuria (PKU) should speak with their primary care physician before taking loratadine. Some of its formulations (e.g., orally disintegrating tablets) may contain phenylalanine which may exacerbate the symptoms of PKU. 

While loratadine has no dangerously significant drug-drug interactions, as with any drug, thorough medication reconciliation is necessary. Drugs that affect the CYP450 enzyme system may have interactions that require therapy modification.[14]

Patients with liver disease or hepatic impairment are advised to exercise caution as the liver extensively metabolizes loratadine, and dose adjustments are necessary per healthcare guidelines. Similarly, individuals with kidney failure or renal impairment should be cautious as such patients will have elevated loratadine concentrations, requiring dose adjustments.[15][16]

According to the American College of Obstetricians and Gynecologists, loratadine should be safe for use during pregnancy; the risk of harm to the fetus is not expected based on limited human data; the drug is pregnancy category B. Caution is advised in breastfeeding; nursing mothers may use the medication short-term while breastfeeding; both loratadine and its active metabolite pass readily into breast milk. There is no known risk of infant harm based on the drug’s properties and currently limited data in humans.[17][18]

Monitoring

Patients taking loratadine require monitoring regarding symptomatic relief, sedation, and any anticholinergic effects (such as dilated pupils and drying of oral mucosa). 

Renal and hepatic function also requires close monitoring by the primary care physician for patients with kidney or liver impairment, with appropriate dose adjustment of the drug made accordingly. 

Cardiac function should also be monitored in individuals with a history of cardiac arrhythmias to prevent loratadine over-medication. 

Loratadine storage should be in a cool, dry place at a temperature of between 68 to 77 degrees Fahrenheit.[2]

Toxicity

Loratadine-induced cardiotoxicity, including cardiac arrhythmias and prolongation of QT-interval, is possible in patients, especially in the elderly, if taking a higher than the recommended 24-hour dose. Though rare, overdosing on loratadine may cause significant toxicity, including agitation and symptoms of the anticholinergic syndrome. Symptoms include, but are not limited to, mydriasis, urinary retention, tachycardia, and skin flushing.[19][20][21] 

Treatment protocol for loratadine toxicity may involve providing emesis (except for patients with impaired consciousness), supplemental oxygen, and cardiac monitoring. Clinicians may give sodium bicarbonate to treat arrhythmias and prolonged QT intervals in patients with suspected toxicity. Alleviation of agitation can be with benzodiazepines due to their high therapeutic index. Adults with symptoms of anticholinergic poisoning due to loratadine toxicity may receive physostigmine antidote therapy (recommended dose is between 0.5 to 2 mg IV). The recommendation is that only a medical toxicologist should supervise antidote therapy.

There is no evidence of abuse potential or dependency with loratadine.

Enhancing Healthcare Team Outcomes

Loratadine is proven to be an effective and safe medication for alleviating symptoms of allergic rhinitis and treating urticaria. The drug is available as an over-the-counter medication; thus, it is essential to have a pharmacist educate the patient on the therapeutic dose of the drug and check their medication profile for any potential interactions. The primary care clinician (MD, DO, PA, NP) must counsel the patient on the importance of reading labels to avoid taking more than the recommended dose to prevent any drug-related toxicities. While loratadine is a relatively safe drug, healthcare providers should inform patients of all the side effects associated with the medication, and medication reconciliation is necessary as with the addition or discontinuing of any drug.

Healthcare providers should also check liver and kidney function before prescribing the medication to individuals with hepatic and renal impairments. Nurses should take a complete mediation history from the patient at each visit, including OTC agents and supplements, and chart these, so all interprofessional healthcare team members have complete patient information. Nursing can also reinforce counseling to the patient on proper dosing and administration of loratadine and watching for adverse effects and patient compliance. Pharmacists can reinforce dosing and administration parameters and check for drug-drug interactions. All members of the interprofessional team, as cited above, need to practice collaborative communication to ensure the best possible patient outcomes for loratadine therapy. [Level 5]

Review Questions

• Access free multiple choice questions on this topic.

• Comment on this article.

References

1.

Church MK, Maurer M. Antihistamines. Chem Immunol Allergy. 2014;100:302-10. [PubMed: 24925410]

2.

Maurer M, Church MK, Gonçalo M, Sussman G, Sánchez-Borges M. Management and treatment of chronic urticaria (CU). J Eur Acad Dermatol Venereol. 2015 Jun;29 Suppl 3:16-32. [PubMed: 26053292]

3.

Pons-Guiraud A, Nekam K, Lahovsky J, Costa A, Piacentini A. Emedastine difumarate versus loratadine in chronic idiopathic urticaria: a randomized, double-blind, controlled European multicentre clinical trial. Eur J Dermatol. 2006 Nov-Dec;16(6):649-54. [PubMed: 17229605]

4.

Church MK, Church DS. Pharmacology of antihistamines. Indian J Dermatol. 2013 May;58(3):219-24. [PMC free article: PMC3667286] [PubMed: 23723474]

5.

Bell RA, Kravitz RL, Wilkes MS. Direct-to-consumer prescription drug advertising and the public. J Gen Intern Med. 1999 Nov;14(11):651-7. [PMC free article: PMC1496757] [PubMed: 10571712]

6.

Cohen JP, Paquette C, Cairns CP. Switching prescription drugs to over the counter. BMJ. 2005 Jan 01;330(7481):39-41. [PMC free article: PMC539854] [PubMed: 15626806]

7.

Baroody FM, Naclerio RM. Antiallergic effects of h2-receptor antagonists. Allergy. 2000;55 Suppl 64:17-27. [PubMed: 11291777]

8.

Negro-Alvarez JM, Funes E, García Cánovas A, Hernández J, García-Sellés FJ, Pagán JA, López-Sánchez JD. Antiallergic properties of antihistamines. Allergol Immunopathol (Madr). 1996 Jul-Aug;24(4):177-83. [PubMed: 8939275]

9.

Church MK. Allergy, Histamine and Antihistamines. Handb Exp Pharmacol. 2017;241:321-331. [PubMed: 28101683]

10.

Hunto ST, Kim HG, Baek KS, Jeong D, Kim E, Kim JH, Cho JY. Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-_kB pathway. Biochem Pharmacol. 2020 Jul;177:113949. [PubMed: 32251678]

11.

Li J, Zhou Y, Aisha M, Wu J, Wang H, Huang F, Sun M. Preparation of loratadine nanocrystal tablets to improve the solubility and dissolution for enhanced oral bioavailability. J Pharm Pharmacol. 2021 Jun 08;73(7):937-946. [PubMed: 33963858]

12.

Cardelús I, Antón F, Beleta J, Palacios JM. Anticholinergic effects of desloratadine, the major metabolite of loratadine, in rabbit and guinea-pig iris smooth muscle. Eur J Pharmacol. 1999 Jun 18;374(2):249-54. [PubMed: 10422766]

13.

Orzechowski RF, Currie DS, Valancius CA. Comparative anticholinergic activities of 10 histamine h2 receptor antagonists in two functional models. Eur J Pharmacol. 2005 Jan 04;506(3):257-64. [PubMed: 15627436]

14.

Ghosal A, Gupta S, Ramanathan R, Yuan Y, Lu X, Su AD, Alvarez N, Zbaida S, Chowdhury SK, Alton KB. Metabolism of loratadine and further characterization of its in vitro metabolites. Drug Metab Lett. 2009 Aug;3(3):162-70. [PubMed: 19702548]

15.

Assanasen P, Naclerio RM. Antiallergic anti-inflammatory effects of h2-antihistamines in humans. Clin Allergy Immunol. 2002;17:101-39. [PubMed: 12113215]

16.

Devillier P, Roche N, Faisy C. Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review. Clin Pharmacokinet. 2008;47(4):217-30. [PubMed: 18336052]

17.

Gupta KK, Anari S. Medical management of rhinitis in pregnancy. Auris Nasus Larynx. 2022 Dec;49(6):905-911. [PubMed: 35131140]

18.

Gonzalez-Estrada A, Geraci SA. Allergy Medications During Pregnancy. Am J Med Sci. 2016 Sep;352(3):326-31. [PubMed: 27650241]

19.

Paakkari I. Cardiotoxicity of new antihistamines and cisapride. Toxicol Lett. 2002 Feb 28;127(1-3):279-84. [PubMed: 12052668]

20.

Liu Y, Cheng L. [Cardiac safety evaluation of loratadine in the treatment of allergic rhinitis in elderly patients]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 Sep;42(9):647-9. [PubMed: 18051560]

21.

Delgado LF, Pferferman A, Solé D, Naspitz CK. Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children. Ann Allergy Asthma Immunol. 1998 Apr;80(4):333-7. [PubMed: 9564984]

Disclosure: Gursharan Sidhu declares no relevant financial relationships with ineligible companies.

Disclosure: Hossein Akhondi declares no relevant financial relationships with ineligible companies.

instructions for use, reviews and effect of the drug

Contents

• 1 Loratadine: instructions for use, indications, contraindications and patient reviews
  • 1.1 Learn about Loratadine: its effect and use in each situation
    • 1.1.1 What is Loratadine ?
    • 1.1.2 How does Loratadine work?
    • 1.1.3 What is Loratadine used for?
    • 1.1.4 How to use Loratadine?
    • 1.1.5 Benefits of Loratadine
    • 1.1.6 How to choose Loratadine?
    • 1.1.7 Conclusions
  • 1.2 How to take Loratadine correctly?
  • 1.3 Effects of Loratadine on the body
  • 1.4 Who should not take Loratadine?
    • 1.4.1 Allergic reaction to drugs
    • 1.4.2 Liver problems
    • 1.4.3 Pregnancy and lactation
    • 1.4.4 Alcohol and Loratadine

  900 05 1. 5 Possible side effects of Loratadine

  • 1.6 Learn how to take Loratadine correctly
  • 1.7 What doctors say about using Loratadine
  • 1.8 What people say about Loratadine
  • 1.9 Comparing Loratadine with other allergy medications
    • 1.9.1 What is Loratadine ?
    • 1.9.2 How does Loratadine compare to other drugs?
    • 1.9.3 Why choose Loratadine?
  • 1.10 Where to buy Loratadine
    • 1.10.1 Online pharmacies
    • 1.10.2 General pharmacies
  • 1.11 Related videos:
  • 1.12 Q&A:
    • • 1.12.0.1 What is Loratadine used for?
      • 1.12.0.2 How to take Loratadine?
      • 1.12.0.3 What are the possible side effects of Loratadine?
      • 1.12.0.4 Can pregnant and lactating women take Loratadine?
      • 1.12.0.5 How long does Loratadine last?
      • 1.12.0.6 What are the reviews about Loratadine?

Loratadine (Loratadine) is an effective antihistamine used to treat allergic reactions and reduce symptoms associated with chronic respiratory disease. Learn more about the action, method of application and side effects of loratadine on our website.

Want to get rid of unpleasant allergy symptoms such as nasal congestion, cough, itching and runny nose? Then Loratadine is the perfect solution for you!

This drug blocks histamine receptors and prevents the development of an allergic reaction. What’s more, Loratadine is long lasting and does not cause drowsiness, making it an ideal choice for people who need to think clearly and sharply throughout the day.

To get the most benefit from Loratadine, follow the directions for use. Read the official instructions for dosage and timing of use. To learn about the results, see the testimonials of our satisfied customers. They are confident in the effectiveness of this drug!

“Loratadine helped me get rid of all my allergy symptoms. I feel much better, and this happens without harm to my health. I highly recommend it to everyone else!”

Our product is safe and effective for most people. Buy Loratadine and experience complete allergy relief today!

Learn about Loratadine: how it works and how to use it in every situation

What is Loratadine?

Loratadine is an over-the-counter antihistamine used to treat and relieve symptoms of various types of allergies such as runny nose, hives, itching, and more. It is available in a variety of forms, including tablets, syrups, and chewables.

How does Loratadine work?

Loratadine works by blocking the action of histamine, a substance that is released in the body in response to an allergen. It helps reduce allergy symptoms such as itching, runny nose, redness, and more. It is a safe and effective drug for the treatment of all types of allergies.

What is Loratadine for?

• Relieve allergy symptoms: itching, runny nose, redness, watery eyes, swelling, etc.
• Urticaria treatment.
• Treatment of rhinitis and sinusitis.
• Help with asthma and pet allergies.

How to use Loratadine?

Loratadine dosage may vary according to age and symptoms. It is usually recommended to take one tablet once a day after meals. It is not recommended to exceed the dose. If you have any doubts, consult your doctor.

Benefits of Loratadine

• Quickly relieves allergy symptoms.
• Does not cause drowsiness or other side effects.
• Effective in the treatment of all types of allergies.
• A safe product that can be used for a long time.

How to choose Loratadine?

Choice of loratadine may depend on symptoms and be individual. However, the general rule is that the higher the concentration of the active substance in the tablets, the more effective the drug will be. If you have difficulty choosing, consult your doctor or consult a pharmacist.

Conclusions

Loratadine is an effective and safe treatment for allergy symptoms. Its wide spectrum of activity and minimal side effects make it one of the most popular drugs for the treatment of allergies. Do not forget that Loratadine is still a medication. Before using it, consult your doctor or pharmacist.

How to take Loratadine correctly?

Loratadine is an effective drug that helps with allergic reactions. However, in order for the effect to be maximum, it is necessary to take the drug correctly.

Loratadine is to be taken once a day, preferably in the evening. For adults and children over 12 years of age, it is recommended to take 10 mg (one tablet) once a day. If necessary, the dose can be increased to 20 mg per day, but only after consulting a doctor.

Loratadine may be taken with or without food, but it is preferable to take the drug with water. Do not exceed the daily dose indicated in the instructions for use, and continue taking more than 10 days without a doctor’s prescription.

Remember that when taking Loratadine, care must be taken while driving and performing potentially hazardous work, as the drug may cause drowsiness. If you have a chronic illness or are taking other medications, be sure to check with your doctor about possible interactions of Loratadine with other medications.

Effects of Loratadine on the body

Loratadine is a drug used to treat allergic reactions. Its action is aimed at blocking the action of histamine – a substance that causes allergic manifestations in the body.

Loratadine reduces allergic symptoms such as itching, skin rashes, runny nose and red eyes. The drug also helps prevent the development of allergic reactions upon contact with allergens.

It is important to remember that Loratadine is not a cure for allergies, but only reduces the manifestation of its symptoms. It is necessary to consult a doctor for an accurate diagnosis and the appointment of a comprehensive treatment.

• The effect of Loratadine is observed already 30 minutes after ingestion and lasts up to 24 hours.
• The drug is effective for both seasonal and year-round allergies.
• Loratadine does not cause drowsiness, which means it can be taken before work or driving.

Loratadine is a reliable and effective way to deal with allergic manifestations. But do not forget that before using any medications, you must consult a doctor and strictly follow the instructions for use.

Who should not take Loratadine?

Loratadine is a drug that helps with allergy symptoms such as runny nose, itching and skin rashes. However, it is not recommended for everyone and may cause side effects in some cases.

Allergic reaction to drugs

If you have ever had an allergic reaction to drugs, you should not take Loratadine. This includes anaphylactic shock, hives, or swelling of the throat. If you have any doubts, consult your doctor before taking the drug.

Liver problems

If you have liver problems, you should contact your doctor before taking Loratadine. The drug can increase the level of chemical compounds in the body, which can lead to side effects.

Pregnancy and lactation

If you are pregnant or breastfeeding, consult your physician before taking Loratadine. Although the drug has not been associated with a negative effect on the fetus, there is still insufficient data on its safety.

Alcohol and Loratadine

While there is no evidence that Loratadine and alcohol may cause an interaction or increase the likelihood of side effects, it is still recommended to avoid alcohol during treatment.

Possible Side Effects of Using Loratadine

Loratadine is a drug that is great for allergies and all kinds of symptoms. But like any drug, it can cause side effects. In order to avoid possible troubles, you need to read the instructions for use and know what side effects may occur when taking it.

One of the most common side effects of Loratadine is drowsiness. In some cases, it can lead to increased fatigue and a feeling of weakness. In addition, headaches and dry mouth may occur.

In rare cases, other side effects may occur when taking Loratadine. They may be associated with a malfunction of the central nervous system and may present with various symptoms such as aggression, irritability, and insomnia. In this case, you need to see a doctor.

• Drowsiness
• Fatigue
• Headache
• Dry mouth

We wish you good health and success in your fight against allergies. Remember to follow the dosage and do not exceed the recommended daily allowances for each age category and health condition.

Learn how to take Loratadine

Loratadine is an antihistamine used to treat allergic reactions.

But how often can it be taken?

The usual dosage of Loratadine for adults is 10 mg per day. However, depending on your health, your doctor may recommend changing the dose or frequency of taking.

If you suffer from allergic reactions, it is recommended that you take Loratadine daily at the same dose. If you have other medical conditions, such as liver or kidney failure, you may need to change your dose of Loratadine or how often you take it.

If you have any questions or concerns about taking Loratadine, be sure to check with your doctor.

Doctors’ comments about the use of Loratadine

Alexander Ivanov, therapist: Loratadine is one of the safest and most effective drugs for the treatment of allergies. I recommend it to my patients with various forms of allergies, such as seasonal runny nose, hives, allergic conjunctivitis, etc. Loratadine quickly relieves allergy symptoms and does not lead to drowsiness or other side effects.

Ekaterina Novikova, dermatologist: My patients often experience allergic skin reactions that can cause itching, redness and even angioedema. Loratadine is an excellent choice for quickly and effectively relieving skin allergy symptoms. The drug does not cause dry skin or other undesirable effects, which is important for patients with sensitive skin.

• Irina Petrova, pediatrician: In my practice, Loratadine has become one of the main drugs for the treatment of allergies in children. It is safe and effective for use in the pediatric age group, as well as quickly alleviating allergy symptoms. Loratadine is available as a syrup, making it easier for children to take.
• Sergey Kuznetsov, otolaryngologist: Allergic rhinitis is a common condition that can cause nasal congestion, runny nose and sneezing. Loratadine is a first-line drug for the treatment of allergic rhinitis. It helps to quickly improve breathing and reduce the frequency of allergy symptoms.

Patient reviews of Loratadine

Loratadine is a drug that helps many people deal with allergic reactions. Many patients who took it left their feedback on its action.

• Anya: I have suffered from allergies for many years. But Loratadin helped me cope with this problem. It is effective and does not cause drowsiness.
• Denis: He pulled me out of an acute allergic attack in half an hour. A stuffy nose thanked loratadine and me.
• Victoria: Loratadine is my indispensable assistant in the fight against allergies. The main thing is that it does not cause any side effects.

These reviews indicate that Loratadine is a really good drug that can help fight allergic reactions without side effects.

Comparison of Loratadine with other allergy medications

Thinking about choosing a safe and effective allergy medication? Consider Loratadine! Despite the availability of alternative drugs, many patients choose this particular drug due to its unique characteristics.

What is Loratadine?

Loratadine is an antihistamine used to reduce the symptoms of allergic reactions. Unlike other antihistamines, Loratadine does not cause drowsiness, which allows patients to remain alert and productive throughout the day.

How does Loratadine compare to other drugs?

• Loratadine vs diphenhydramine: Diphenhydramine often causes drowsiness, while Loratadine has almost no such effect.
• Loratadine vs ceterizine: Both drugs work in the same way, but Loratadine may seem like a better choice due to lack of drowsiness.
• Loratadine vs fexofenadine: Both drugs do not usually cause drowsiness, but loratadine may reduce the risk of heart problems in patients over 60 years of age.

Why choose Loratadine?

Patients choose Loratadine because of its safety and lack of drowsiness – the drug can be taken at any time of the day. In addition, it is well tolerated and usually does not cause side effects. If you are looking for an effective allergy medication without the annoying side effects, Loratadine is a great choice!

Where to buy Loratadine

Loratadine is one of the most popular drugs for the treatment of allergies. This drug works around the clock and provides fast relief from the symptoms of allergic reactions. If you are looking for a place to buy Loratadine, we can help you find the best stores and pharmacies where you can get this drug at an affordable price.

Online pharmacies

• Apteka.ru is a large online drug store where you can find many drugs, including Loratadine. A convenient search will help you choose the right product, and fast delivery will ensure its prompt delivery to your home.
• DoktorStoletov is an online pharmacy that allows you to order any medicine at a bargain price. Also here you can get advice from a pharmacist and arrange delivery to the nearest post office for the convenience of buyers.

Ordinary pharmacies

If you prefer to buy medicines in ordinary pharmacies, you should pay attention to the following stores:

1. Rigla is a chain of pharmacies operating in Russia since 1977, where you can easily find Loratadin and other drugs. Rigla’s staff is always ready to help with the choice of the right drug and give professional advice.
2. Pharmacy Europharm is a well-known pharmacy with a large number of medicines. Loratadine can be bought here at an affordable price, and you can also get a free consultation from a pharmacist.

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FAQ:

What is Loratadine used for?

Loratadine is used to treat allergic reactions such as runny nose, nasal congestion, coughing, sneezing, itchy eyes, watery eyes, and skin rash. It can also be used to prevent allergic reactions before exposure to an allergen, such as before visiting pets.

How to take Loratadine?

The dosage of the drug depends on the age and health of the patient. Generally, for adults and children over 12 years of age, it is recommended to take 1 tablet (10 mg) per day. For children 2 to 12 years of age, dosage depends on weight. In any case, you must follow the instructions for the drug and consult your doctor.

What are the possible side effects of Loratadine?

In rare cases, headache, drowsiness, dizziness, nausea, dry mouth, fatigue, rarely allergic skin reactions may occur. If you experience any side effects, stop taking it immediately and seek medical attention.

Can pregnant and lactating women take Loratadine?

Loratadine is not recommended during pregnancy or lactation as its safety to the fetus and child has not been established. If you are pregnant or breastfeeding, you should seek medical advice.

How long does Loratadine last?

Loratadine lasts approximately 24 hours, so it is usually taken once a day. However, for maximum effect, it is recommended to take it throughout the period you are in contact with the allergen.

What are the reviews about Loratadine?

Reviews of Loratadine varied. Some users note its effectiveness in treating allergies. They report that it does not cause drowsiness compared to other drugs and quickly relieves allergy symptoms. However, there are also negative reviews associated with the occurrence of side effects such as headache and nausea. In general, however, Loratadine is a popular and effective drug for the treatment of allergic reactions.

What helps, analogues, dosage, composition POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS REQUIRED. 388 Article content

• Loratadine: active ingredient
• Loratadine: dosage
• Loratadine: composition
• Loratadine: what pills
• Loratadine during pregnancy
• Loratadine: contraindications
• Loratadine: after how long does it work?
• Loratadine: analogues
• Desloratadine and Loratadine: what is the difference
• Loratadine or Suprastin: which is better
• Ask an expert on the topic of the article

nuts, seafood, eggs and milk. We talk about Loratadine – an antiallergic drug: its active substance, dosage, composition, indications, use during pregnancy, contraindications and compare it with analogues.

All products Loratadine

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Loratadine: active ingredient

Loratadine contains the active ingredient of the same name. The drug relieves allergy symptoms: itching, swelling, redness, runny nose, watery eyes, sneezing.

Loratadine dosage

Loratadine is available as plain and lozenge tablets at a dosage of 10 mg, 0.1% oral suspension, 0.1% oral solution, 0.1% syrup. Solution, syrup and suspension contain 1 mg loratadine per 1 ml. For ease of dosing, a measuring spoon is included.

Loratadine: composition

The composition of Loratadine depends on the dosage form. The active substance in them is the same, but the composition of the auxiliary components is different.

Loratadine tablets, depending on the manufacturer, consist of cellulose, silicon dioxide, magnesium stearate, starch, lactose, sodium lauryl sulfate and sodium carboxymethyl starch.

Syrup, solution and suspension Loratadine, depending on the manufacturer, contains:

• citric acid
• succinic acid,
• sodium benzoate,
• sucrose,
• propylene glycol,
• glycerol, 10
• aspartame,
• sorbitol,
• fragrance,
• water.

Aspartame and sorbitol may cause diarrhea. Patients prone to allergies are advised to study the composition in order to exclude a reaction.

Loratadine: for what tablets

Loratadine is used for:

• seasonal and perennial rhinitis,
• conjunctivitis
• hay fever
• urticaria
• angioedema
• pseudo-allergic reactions
• pruritic dermatoses
• insect sting allergies

You may be interested in: The most effective allergy remedies for children

Loratadine during pregnancy

There is insufficient data on the use of Loratadine during pregnancy. But animal studies have not found increased risks to the fetus. However, Loratadine is used during pregnancy only if the expected benefit to the mother outweighs the potential risk to the fetus.

Loratadine contraindications

Loratadine is contraindicated in the following conditions:

• hypersensitivity to drug components
• lactation
• children up to 3 years – for tablets
• children under 2 years old – for syrup, solution and suspension
• lactase deficiency, lactose intolerance, glucose-galactose malabsorption

Loratadine: how long does it take to work?

Loratadine works half an hour after ingestion. The maximum effect develops after 8-12 hours and lasts up to a day.

Loratadine: before or after meals?

The effectiveness of the drug does not depend on food intake. Therefore, Loratadine can be taken before, during and after meals.

Loratadine: analogues

Do you want to understand the analogues of drugs in order to skillfully select drugs for your budget? Our manual from expert pharmacists “Analogues of popular drugs” will help you with this! Getting a training manual is easy: subscribe to our social networks and write “analogues” in the messages.

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There are 37 drugs containing loratadine available in Russia. They can be replaced with each other without consulting a doctor. But we recommend that you consult with a pharmacist to find the right dosage and dosage form.

Loratadine or Cetrin: which is better

Cetrin contains another active ingredient, cetirizine. Its maximum effect develops faster than when taking Loratadine: after 1 hour. Cetrin is contraindicated in children under 6 years of age, and Loratadin – up to 3 years.

Cetrin is contraindicated in pregnancy, and if breastfeeding, the use of the drug should be consulted with a doctor. Be wary appoint patients with chronic renal failure and the elderly, and Loratadine – with liver failure.

Take 5-10 mg of Cetrin 1-2 times a day. In patients with chronic renal failure, use 5 mg per day or every other day, depending on the severity of the condition.

Desloratadine and Loratadine: what is the difference

Desloratadine contains the active ingredient of the same name. The maximum effect of Desloratadine develops 3-4 times faster than Loratadine: after 3 hours. Desloratadine causes headache, dry mouth, and fatigue in 1-10% of cases. The incidence of side effects of Loratadine is 0.0001%.

Desloratadine tablets are contraindicated in patients under 12 years of age. Patients with severe renal insufficiency are better to choose Loratadine, and with hepatic insufficiency – Desloratadine. Desloratadine is taken with or without food once a day.

Loratadin or Suprastin: which is better

Suprastin contains the active ingredient chloropyramine hydrochloride. The therapeutic effect develops within 15-30 minutes and reaches a maximum in the first hour after administration. It keeps for 3-6 hours.

Suprastin, unlike Loratadine, penetrates well into the central nervous system, and therefore often causes drowsiness. Patients who drive a car or work in hazardous industries are better off choosing Loratadine.

Suprastin is contraindicated in patients under 3 years of age, with an attack of bronchial asthma, pregnant and lactating women. Patients with angle-closure glaucoma, impaired renal function, prostate adenoma and urinary retention should choose Loratadine.

Suprastin should be taken more often than Loratadine: 3-4 times a day. In addition, it is drunk with meals. Whereas Loratadine can be taken with or without food.

Loratadine is an antiallergic drug. It contains the active ingredient of the same name. The drug is produced in the form of simple tablets and lozenges at a dosage of 10 mg, 0.1% suspension, solution and syrup for oral administration.