What are the primary uses of Coreg. How does carvedilol work to improve heart health. What are the common side effects of taking Coreg. When should you consult a doctor while using carvedilol.

Understanding Coreg: A Powerful Medication for Heart Health

Coreg, also known by its generic name carvedilol, is a crucial medication in the treatment of various cardiovascular conditions. This article delves into the uses, mechanisms, side effects, and precautions associated with Coreg, providing valuable insights for patients and healthcare professionals alike.

The Primary Uses of Coreg in Cardiovascular Treatment

Coreg serves multiple purposes in managing heart-related issues. Its primary uses include:

• Treating high blood pressure (hypertension)
• Managing heart failure
• Improving survival chances after a heart attack in patients with reduced heart pumping function

By effectively addressing these conditions, Coreg plays a vital role in preventing serious complications such as strokes, heart attacks, and kidney problems.

How does Coreg work to improve cardiovascular health?

Coreg belongs to a class of drugs known as alpha and beta blockers. It functions by blocking the action of certain natural substances in the body, particularly epinephrine, on the heart and blood vessels. This mechanism results in several beneficial effects:

1. Lowering heart rate
2. Reducing blood pressure
3. Decreasing strain on the heart

These combined effects make Coreg an effective tool in managing various cardiovascular conditions and improving overall heart health.

Proper Usage and Dosage Guidelines for Coreg

To ensure maximum benefit and minimize potential side effects, it’s crucial to follow the prescribed dosage and administration guidelines for Coreg:

• Take Coreg orally with food, typically twice daily
• Follow your doctor’s instructions regarding dosage, which is based on your medical condition and response to treatment
• Start with a low dose, gradually increasing as directed by your healthcare provider
• Take the medication regularly at the same times each day for optimal results

Is there a specific timeframe for Coreg to take effect? For treating high blood pressure, it may take 1 to 2 weeks before you experience the full benefit of the medication. However, it’s essential to continue taking Coreg as prescribed, even if you feel well.

Potential Side Effects and How to Manage Them

While Coreg is generally well-tolerated, some patients may experience side effects. Common side effects include:

• Dizziness
• Lightheadedness
• Drowsiness
• Diarrhea
• Impotence
• Tiredness

To minimize the risk of dizziness and lightheadedness, it’s advisable to rise slowly from a sitting or lying position. The risk of dizziness is highest within the first hour after taking your dose. Taking Coreg with food and starting with a low dose can help reduce these side effects.

Can Coreg affect blood circulation in extremities?

Yes, Coreg may reduce blood flow to your hands and feet, causing them to feel cold. This effect can be exacerbated by smoking, so it’s recommended to dress warmly and avoid tobacco use while taking this medication.

Recognizing Serious Side Effects and When to Seek Medical Attention

While most side effects of Coreg are mild, some can be serious and require immediate medical attention. Contact your doctor promptly if you experience any of the following:

• Very slow heartbeat
• Severe dizziness or fainting
• Unusual weakness
• Signs of kidney problems (such as changes in urine output)
• Numbness or tingling in hands or feet
• Blue discoloration of fingers or toes
• Easy bruising or bleeding
• Mental or mood changes (confusion, depression)
• Seizures

In rare cases, Coreg may cause new or worsening symptoms of heart failure, especially at the beginning of treatment. Seek immediate medical help if you develop shortness of breath, swelling in ankles or feet, unusual tiredness, or sudden weight gain.

Important Precautions and Drug Interactions

Before starting Coreg, it’s crucial to inform your healthcare provider about your complete medical history and any allergies. Particular attention should be paid to:

• Certain types of heartbeat or heart rhythm problems
• Breathing issues (asthma, chronic bronchitis, emphysema)
• Severe heart failure requiring hospitalization
• Liver or kidney disease
• Blood circulation problems

Are there any specific drug interactions to be aware of with Coreg? Yes, Coreg can interact with various medications, potentially altering their effectiveness or increasing the risk of side effects. Some notable interactions include:

• Other blood pressure medications
• Certain antidepressants
• Drugs used to treat diabetes
• Medications that affect heart rhythm

Always provide your healthcare provider with a complete list of all medications, supplements, and herbal products you’re taking to avoid potential interactions.

Special Considerations for Specific Patient Groups

Certain groups of patients may require special attention when using Coreg:

Pregnant and breastfeeding women

Coreg should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It’s unknown if Coreg passes into breast milk, so breastfeeding mothers should consult their doctor before using this medication.

Elderly patients

Older adults may be more sensitive to the side effects of Coreg, particularly dizziness and lightheadedness. Careful monitoring and possible dose adjustments may be necessary for this population.

Patients with diabetes

Coreg may mask the symptoms of low blood sugar (hypoglycemia). Diabetic patients should monitor their blood sugar levels closely while taking this medication.

Lifestyle Modifications to Enhance Coreg’s Effectiveness

While Coreg is an effective medication for managing cardiovascular conditions, combining it with lifestyle modifications can enhance its benefits:

• Maintain a heart-healthy diet low in saturated fats and rich in fruits, vegetables, and whole grains
• Engage in regular physical activity as recommended by your healthcare provider
• Limit alcohol consumption and quit smoking
• Manage stress through relaxation techniques or counseling
• Monitor your blood pressure regularly at home

By adopting these lifestyle changes alongside your Coreg regimen, you can significantly improve your overall cardiovascular health and potentially reduce your reliance on medication over time.

Monitoring and Follow-up Care While Taking Coreg

Regular monitoring is essential when using Coreg to ensure its effectiveness and detect any potential issues early. Your healthcare provider may recommend:

• Regular blood pressure checks
• Periodic blood tests to assess liver and kidney function
• Electrocardiograms (ECGs) to monitor heart rhythm
• Symptom assessments to evaluate the medication’s effectiveness

How often should follow-up appointments be scheduled? Initially, your doctor may want to see you more frequently to adjust your dosage and monitor for side effects. Once your condition stabilizes, follow-up visits may be less frequent, typically every 3 to 6 months.

The importance of medication adherence

Adhering to your prescribed Coreg regimen is crucial for managing your cardiovascular condition effectively. Skipping doses or stopping the medication abruptly can lead to serious complications. If you’re experiencing difficulties with your medication routine, discuss this with your healthcare provider to find suitable solutions.

Alternative Treatments and Combination Therapies

While Coreg is highly effective for many patients, it may not be suitable for everyone. In some cases, alternative treatments or combination therapies may be considered:

• Other types of beta-blockers or ACE inhibitors
• Calcium channel blockers
• Diuretics
• Angiotensin receptor blockers (ARBs)

Your healthcare provider will determine the most appropriate treatment plan based on your individual medical history, current condition, and potential drug interactions.

Combining Coreg with other heart medications

In some cases, Coreg may be prescribed in combination with other heart medications to achieve optimal results. Common combinations include:

• Coreg with ACE inhibitors for heart failure management
• Coreg with diuretics for blood pressure control
• Coreg with antiplatelet medications for post-heart attack care

These combination therapies can provide synergistic effects, enhancing the overall management of cardiovascular conditions.

Long-term Outlook and Prognosis for Patients on Coreg

For many patients, long-term use of Coreg can significantly improve their cardiovascular health and quality of life. Studies have shown that Coreg can:

• Reduce the risk of mortality in heart failure patients
• Improve left ventricular function after a heart attack
• Effectively control blood pressure in hypertensive patients

However, the long-term prognosis can vary depending on individual factors such as the severity of the underlying condition, adherence to treatment, and lifestyle choices.

Can patients eventually stop taking Coreg?

In some cases, patients may be able to reduce or discontinue Coreg under close medical supervision. This typically occurs when:

• Blood pressure has been well-controlled for an extended period
• Heart function has significantly improved
• Lifestyle modifications have led to substantial improvements in cardiovascular health

However, it’s crucial never to stop taking Coreg abruptly or without consulting your healthcare provider, as this can lead to serious complications.

Emerging Research and Future Developments in Carvedilol Treatment

Ongoing research continues to explore new applications and potential benefits of carvedilol in various medical fields:

• Use in treating certain types of arrhythmias
• Potential neuroprotective effects in Parkinson’s disease
• Investigation of carvedilol’s antioxidant properties in cancer treatment
• Development of extended-release formulations for once-daily dosing

These areas of research may lead to expanded uses for carvedilol in the future, potentially benefiting a wider range of patients.

Personalized medicine approaches with Coreg

Advancements in genetic testing and personalized medicine are paving the way for more tailored approaches to Coreg treatment. Researchers are investigating genetic markers that may predict:

• Individual response to carvedilol therapy
• Likelihood of experiencing specific side effects
• Optimal dosing strategies based on genetic profiles

These developments could lead to more precise and effective use of Coreg in the future, maximizing benefits while minimizing risks for each patient.

Patient Education and Support Resources

Proper education and support are crucial for patients taking Coreg to ensure optimal treatment outcomes. Various resources are available to help patients better understand their medication and manage their condition:

• Patient information leaflets provided by pharmacies
• Online resources from reputable medical organizations
• Support groups for individuals with heart conditions
• Medication reminder apps to improve adherence
• Nutritional counseling for heart-healthy diets

Patients are encouraged to actively engage with these resources and maintain open communication with their healthcare providers to address any concerns or questions about their Coreg treatment.

The role of caregivers in Coreg treatment

Caregivers play a vital role in supporting patients taking Coreg, particularly for elderly individuals or those with complex medical conditions. Caregivers can assist by:

• Helping to manage medication schedules
• Monitoring for side effects
• Encouraging adherence to lifestyle modifications
• Accompanying patients to medical appointments
• Providing emotional support throughout the treatment journey

Healthcare providers should consider involving caregivers in patient education and treatment planning to ensure comprehensive care and support.

Coreg Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Carvedilol is used to treat high blood pressure and heart failure. It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Carvedilol belongs to a class of drugs known as alpha and beta blockers.

How to use Coreg

See also Warning section.

Read the Patient Information Leaflet if available from your pharmacist before you start taking carvedilol and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with food as directed by your doctor, usually twice daily.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

For the treatment of high blood pressure, it may take 1 to 2 weeks before you get the full benefit of this drug. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase, or you have worsening symptoms of heart failure like increased shortness of breath).

Side Effects

See also Warning and Precautions sections.

Dizziness, lightheadedness, drowsiness, diarrhea, impotence, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. The risk of dizziness is highest within 1 hour after you take your dose. Taking this medication with food and starting treatment with a low dose and slowly increasing your dose as directed by your doctor help to reduce the risk of dizziness.

This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid tobacco use.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: very slow heartbeat, severe dizziness, fainting, unusual weakness, signs of kidney problems (such as change in the amount of urine), numbness/tingling of the hands/feet, blue fingers/toes, easy bruising/bleeding, mental/mood changes (such as confusion, depression), seizures.

Although this medication may be used to treat heart failure, some people may rarely develop new or worsening symptoms of heart failure, especially at the start of carvedilol treatment. Tell your doctor right away if you develop any of these serious side effects: shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking carvedilol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain types of heartbeat/heart rhythm problems (such as slow/irregular heartbeat, sick sinus syndrome, second- or third-degree atrioventricular block), breathing problems (such as asthma, chronic bronchitis, emphysema), severe heart failure requiring hospitalization, liver disease, kidney disease, blood circulation problems (such as Raynaud’s disease, peripheral vascular disease), serious allergic reactions including those needing treatment with epinephrine, overactive thyroid disease (hyperthyroidism), a certain type of tumor (pheochromocytoma), other heart problems (such as Prinzmetal’s variant angina), a certain muscle disease (myasthenia gravis), certain eye problems (cataracts, glaucoma).

This drug may make you dizzy or drowsy or cause you to faint. This is most likely to occur within 1 hour after taking your dose, especially when you start carvedilol treatment or any time your doctor increases your dose. During these periods, avoid driving and doing hazardous tasks. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

People who wear contact lenses may have dry eyes while taking this medication.

Before having surgery (including cataract/glaucoma eye surgery), tell your doctor or dentist if you are taking or have ever taken this medication, and about all the other products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you have diabetes, this product may mask the fast/pounding heartbeat you would usually feel when your blood sugar falls too low (hypoglycemia). Other symptoms of low blood sugar, such as dizziness and sweating, are unaffected by this drug. This product may also make it harder to control your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Children may be at greater risk for low blood sugar (hypoglycemia), especially if they are vomiting or not eating regularly. To help prevent low blood sugar, feed children on a regular schedule. If your child cannot eat regularly, is vomiting, or has symptoms of low blood sugar (such as sweating, seizures), stop this medication and tell the doctor right away.

Older adults may be more sensitive to the side effects of this drug, especially dizziness and lightheadedness.

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using carvedilol. Carvedilol may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.

It is unknown if carvedilol passes into breast milk. However, it is unlikely to pass into breast milk in large amounts. There is a low risk that it may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

One product that may interact with this drug is: fingolimod.

Some products have ingredients that could raise your heart rate or blood pressure or worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Does Coreg interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: very slow heartbeat, severe dizziness, fainting, slow/shallow breathing, seizures.

Do not share this medication with others.

Lifestyle changes that may help this medication work better include exercising, stopping smoking, and eating a low-cholesterol/low-fat diet. Consult your doctor for more details.

Have your blood pressure and pulse (heart rate) checked regularly while taking this medication. Learn how to monitor your own blood pressure and pulse at home, and share the results with your doctor.

Lab and/or medical tests (such as kidney/liver function) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Coreg 6.25 mg tablet

Color: whiteShape: ovalImprint: SB 4140 SB 4140

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Coreg 12.5 mg tablet

Color: whiteShape: ovalImprint: SB 4141 SB 4141

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Coreg 3.125 mg tablet

Color: whiteShape: ovalImprint: SB 39

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Coreg 25 mg tablet

Color: whiteShape: ovalImprint: SB 4142 SB 4142

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Carvedilol: a medicine used to treat high blood pressure and prevent angina, heart disease and stroke.

1. About carvedilol

Carvedilol is a beta blocker.

It’s used to treat high blood pressure (hypertension) and helps prevent:

• heart disease
• heart attacks
• strokes

It can also be given with other medicines to treat heart failure and to prevent chest pain caused by angina.

Carvedilol is only available on prescription. It comes as tablets.

2. Key facts

• Carvedilol slows down your heart rate and makes it easier for your heart to pump blood around your body.
• You’ll usually take carvedilol once or twice a day.
• It usually starts to work after about 1 hour. But it will take days or weeks for it to reach its full effect.
• Common side effects of carvedilol include headaches and feeling tired or dizzy.
• Do not stop taking carvedilol suddenly. This can make your condition worse, especially if you have heart disease.

3. Who can and cannot take carvedilol

Carvedilol can be taken by most adults. It can sometimes be prescribed by a specialist for children aged 2 years and over.

Carvedilol is not suitable for some people. Tell your doctor before starting the medicine if you have:

• ever had an allergic reaction to carvedilol or any other medicines
• lung disease or asthma
• heart failure that is getting worse
• have low blood pressure (hypotension) or a slow heart rate
• a liver problem
• serious circulation problems in your arms and legs, such as Raynaud’s

4.

How and when to take carvedilol

When you start taking carvedilol, your doctor may advise you to take your first dose just before you go to bed. This is because it can make you feel dizzy.

After the first dose, if you do not feel dizzy, you can take your medicine in the morning. If you do feel dizzy, it’s best to keep taking your medicine at bedtime.

It’s best to take carvedilol at the same time each day.

If you take it twice a day, you’ll usually have 1 dose in the morning and 1 dose in the evening. Leave 10 to 12 hours between doses if you can.

Swallow the tablets whole with a drink of water. Do not chew or crush them.

Carvedilol does not usually upset your stomach, so you can take it with or without food. However, if you are taking carvedilol for heart failure, it’s best to take the tablets with food. This will help reduce the risk of you feeling dizzy or faint when you stand up.

If you find tablets difficult to swallow, some strengths have a score line to help you break the tablet in half. Check the information leaflet that comes with your medicine to see if you can do this.

Dosage

Carvedilol tablets come in 4 different strengths – 3.125mg, 6.25mg, 12.5mg and 25mg.

How much you take depends on why you need carvedilol.

The usual starting dose to treat:

• high blood pressure is 12.5mg once a day for 2 days – this is increased to 25mg, taken once a day. If your blood pressure does not go down enough your doctor may increase your dose to up to 50mg a day. This can be taken as a single dose or split into 2 doses.
• heart failure is 3.125mg, taken twice a day for 2 weeks. Your doctor will then slowly increase the dose every 2 weeks up to a maximum of 25mg to 50mg (depending on your weight).
• angina is 12.5mg, taken twice a day for 2 days – this is increased to 25mg, taken twice a day.

If your child is prescribed carvedilol, the doctor will use their weight to work out the right dose.

What if I forget to take it?

If you miss a dose of carvedilol, take it as soon as you remember, unless it’s nearly time for your next dose. In this case, just leave out the missed dose and take your next dose as normal.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.

What if I take too much?

The amount of carvedilol that can lead to an overdose varies from person to person.

Taking too much carvedilol can lower your blood pressure, slow your heart rate, and make it difficult to breathe.

Urgent advice: Contact 111 for advice now if:

• you take too much carvedilol

Call 111 or go to 111.nhs.uk

If you need advice for a child under the age of 5 years, call 111.

5. Side effects

Like all medicines, carvedilol can cause side effects in some people, but many people have no side effects or only minor ones.

Side effects usually improve as your body gets used to the medicine.

Common side effects

These common side effects may happen in more than 1 in 100 people. They’re usually mild and last a few days after starting the medicine or increasing your dose.

Talk to your doctor or pharmacist if these side effects bother you or do not go away:

• feeling dizzy
• headaches
• feeling tired
• feeling or being sick (nausea or vomiting)
• cold fingers or toes

Serious side effects

It happens rarely, but some people have serious side effects when taking carvedilol.

Tell a doctor straight away if you have:

• nose bleeds that last for more than 10 minutes, unexplained bruising, or you bruise more easily than usual – these can be signs of low numbers of platelets in your blood (thrombocytopenia)
• high temperature, sore throat, mouth sores, toothache, flu-like symptoms – these can be signs of a low number of white blood cells (leukopenia)
• shortness of breath with a cough that gets worse when you exercise (like walking up the stairs), swollen ankles or legs, chest pain, or an irregular heartbeat – these may be signs of other heart problems
• shortness of breath, wheezing and tightening of your chest – these can be signs of lung problems
• yellow skin or the whites of your eyes turn yellow – these can be signs of liver problems

Serious allergic reaction

In rare cases, it’s possible to have a serious allergic reaction (anaphylaxis) to carvedilol.

Immediate action required: Call 999 or go to A&E now if:

• you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
• you’re wheezing
• you get tightness in the chest or throat
• you have trouble breathing or talking
• your mouth, face, lips, tongue or throat start swelling

You could be having a serious allergic reaction and may need immediate treatment in hospital.

These are not all the side effects of carvedilol. For a full list see the leaflet inside your medicines packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

6. How to cope with side effects of carvedilol

What to do about:

• feeling dizzy – as your body gets used to carvedilol this side effect should wear off. If carvedilol makes you feel dizzy, stop what you’re doing and sit or lie down until you feel better. Do not drive or operate machinery until you feel OK again. Try to avoid alcohol as it’ll make you feel worse.
• headaches – make sure you rest and drink plenty of fluids. Ask your pharmacist to recommend a painkiller. Do not drink too much alcohol. Headaches usually go away after the first week of taking carvedilol. Talk to your doctor if the headaches last more than a week or are severe.
• feeling tired – do not drive, ride a bike, or use tools or machinery if you’re feeling tired. Do not drink any alcohol as this will make you feel more tired.
• feeling sick or being sick – stick to simple meals and do not eat rich or spicy food. It might help to take your carvedilol after a meal or snack. If you’re being sick, try drinking small, frequent sips of water to avoid dehydration.
• cold fingers or toes – put your hands or feet under warm running water, massage them, and wiggle your fingers and toes. Do not smoke or have drinks with caffeine, as this can make your blood vessels narrower and restrict your blood flow. It’s best not to wear tight watches or bracelets as well. Try wearing mittens (they’re warmer than gloves) and warm socks. Speak to your doctor if this side effect bothers you.

7. Pregnancy and breastfeeding

Carvedilol and pregnancy

Carvedilol is not usually recommended if you’re pregnant.

If you’re trying to get pregnant or you’re already pregnant, talk to your doctor about taking carvedilol. It may be possible to change to other medicines that are more suitable when you’re pregnant, such as labetalol or nifedipine.

Carvedilol and breastfeeding

If your doctor or health visitor says that your baby is healthy, it’s OK to take carvedilol while breastfeeding.

There is no information about whether carvedilol passes into breast milk, but it would only be expected to pass through in small amounts. It’s unlikely to cause any side effects in your baby.

If you notice that your baby isn’t feeding as well as usual, or seems unusually sleepy, or if you have any other concerns about your baby, then talk to your health visitor, midwife or doctor as soon as possible.

Non-urgent advice: Tell your doctor if you’re:

• trying to get pregnant
• pregnant
• breastfeeding

Find out more about high blood pressure and pregnancy.

8. Cautions with other medicines

There are some medicines that can affect the way carvedilol works.

Tell your doctor if you’re taking:

• other medicines for high blood pressure – when taken together with carvedilol, they can sometimes lower your blood pressure too much
• other medicines that can lower your blood pressure – these include some antidepressants, nitrates (for chest pain), baclofen (a muscle relaxant), medicines for an enlarged prostate gland like tamsulosin, or levodopa (for Parkinson’s disease)
• medicines for an irregular heartbeat such as amiodarone or flecainide
• medicines for asthma or chronic obstructive pulmonary disease (COPD)
• medicines for diabetes, particularly insulin – carvedilol may make it more difficult to recognise the warning signs of low blood sugar. Speak to your doctor if you have low blood sugar levels without getting any warning signs. You should check your blood sugar after exercise, and follow usual advice about checking it before driving, or operating machinery.
• medicines that treat nose or sinus congestion, or other cold remedies (including those you can buy in the pharmacy)
• medicines for allergies, such as ephedrine, noradrenaline or adrenaline
• non-steroidal anti-inflammatory medicines (NSAIDs), such as ibuprofen, diclofenac and naproxen – these medicines may increase your blood pressure

Mixing carvedilol with herbal remedies and supplements

There’s very little information about taking herbal remedies and supplements with carvedilol. However, some herbal products, such as cod liver oil, hawthorn and garlic tablets may cause low blood pressure (hypotension).

Important:
Medicine safety

Tell your doctor or pharmacist if you’re taking any other medicines, including herbal medicines, vitamins or supplements.

9. Common questions about carvedilol

How does carvedilol work?

Carvedilol is a type of medicine called a beta blocker.

Like other beta blockers, carvedilol works by slowing down your heart rate and making it easier for your heart to pump blood around your body.

It also works like an alpha blocker to widen some of your blood vessels. This helps lower your blood pressure.

For angina, carvedilol works by improving the blood supply to your heart. Angina is chest pain that comes on when not enough blood gets to the muscles of the heart. It usually happens because the arteries to the heart become hardened and narrowed.

Carvedilol widens the arteries so more oxygen gets to the heart and chest pain is prevented. It also slows your heart down and makes it beat more effectively. This reduces the amount of oxygen needed by your heart muscle and prevents angina.

How long does it take to work?

Carvedilol usually starts to work after about 1 hour. But it will take days or weeks to reach its full effect.

You may not feel any different when you take carvedilol for high blood pressure, but this does not mean it’s not working. It’s important to keep taking your medicine.

How long will I take it for?

Usually, treatment with carvedilol is long term. It may be for the rest of your life.

Can I take carvedilol for a long time?

Most people take carvedilol for a long time with no problems. In fact, it works best when you take it long term.

What will happen if I stop taking it?

Talk to your doctor if you want to stop taking carvedilol. If you’re bothered by side effects, your doctor may be able to prescribe a different medicine instead.

How does it compare with other medicines for high blood pressure?

Carvedilol works as well as other beta blockers to reduce blood pressure, but it’s mainly used to prevent angina or heart failure because it also widens the blood vessels.

The main difference with carvedilol is that it can affect other parts of your body too, such as your lungs.

Other medicines used to lower blood pressure work in different ways to beta blockers. These include:

• ACE inhibitors such as ramipril and lisinopril
• angiotensin receptor blockers like losartan
• calcium channel blockers like amlodipine
• medicines that make you pee more (diuretics) like indapamide

The medicine your doctor prescribes first depends on your age and ethnicity. If you’re under 55 years old, you’ll usually be offered an ACE inhibitor or an angiotensin receptor blocker. If you’re 55 years old or over, or of African Caribbean or black African origin, you’ll usually be offered a calcium channel blocker.

If you are bothered by side effects, you may have to try a different blood pressure medicine. Many people need to take a combination.

How does it compare with other medicines for chest pain and angina?

There are lots of other medicines to prevent angina attacks.

They include:

• calcium channel blockers such as diltiazem and amlodipine
• nitrates like isosorbide mononitrate
• medicines such as ranolazine, nicorandil or ivabradine

If carvedilol does not work for you, or you cannot take carvedilol or other beta blockers because of side effects, you may be able to switch to another medicine.

Your doctor will be able to decide which medicine is best for you. Some people may need to take a combination of medicines to control their angina symptoms.

How does it compare with other medicines that treat heart failure?

Carvedilol is used with other medicines to treat heart failure and prevent complications, These can include ACE inhibitors (like ramipril and lisinopril) or angiotensin receptor blockers (like losartan).

Other beta blockers like bisoprolol and nebivolol can be used instead of carvedilol in a similar way.

Will I need to stop carvedilol before surgery?

Tell your doctor you’re taking carvedilol if you’re going to be put to sleep (using general anaesthetic) or have any kind of major operation.

Your doctor may advise you to stop taking carvedilol before surgery.

This is because carvedilol can lower your blood pressure too much when it’s combined with some general anaesthetics.

Can I drink alcohol?

Drinking alcohol can increase the blood pressure-lowering effect of carvedilol. This can make you feel dizzy or lightheaded.

During the first few days of taking carvedilol, or after an increase in your dose, it is best to stop drinking alcohol until you see how the medicine affects you.

If you find carvedilol makes you feel dizzy it’s best to stop drinking alcohol.

Is there any food or drink I need to avoid?

You can eat and drink normally while taking carvedilol.

Eating a healthy, balanced diet can help your heart condition.

Will it affect my contraception?

Carvedilol will not stop your contraception working.

But some types of combined hormonal methods of contraception, such as the combined pill and contraceptive patch, are not usually recommended for women with high blood pressure.

Talk to your doctor if you’re taking a combined hormonal contraceptive.

If carvedilol makes you vomit, your contraceptive pills may not protect you from pregnancy. Look on the pill packet to find out what to do.

Read more about what to do if you’re on the pill and you’re being sick.

Will it affect my fertility?

There’s no clear evidence to suggest that taking carvedilol will reduce fertility in either men or women.

If you’re trying for a baby or having problems getting pregnant while on carvedilol, speak to your doctor.

Will it affect my sex life?

Some people on carvedilol say their sex drive goes down and some men say they cannot get an erection.

There’s not enough evidence to say that carvedilol causes this.

If you’re having problems with your sex life, talk to your doctor.

Do I need to avoid playing sports?

You do not need to stop playing sports if you take carvedilol. But it’s a good idea not to push yourself too much.

Regular exercise is good for you because it lowers blood pressure by keeping your heart and blood vessels in good condition.

However, in some sports carvedilol may not be allowed if you’re competing at a very high level.

Can I drive or ride a bike?

Carvedilol can make you feel tired or dizzy, especially when you first start taking it or after increasing your dose.

If this happens to you, do not drive a car, ride a bike, or use tools or machinery until you feel OK again.

Can lifestyle changes help heart problems?

If you have heart problems, you can boost the health of your heart by making some lifestyle changes.

It’s a good idea to:

• quit smoking – not smoking will bring down your blood pressure and relieve heart failure symptoms.
• cut down on alcohol – drinking too much alcohol raises blood pressure over time and makes heart failure worse. Drinking alcohol while you’re taking carvedilol can make you feel dizzy or lightheaded.
• exercise – regular exercise lowers blood pressure by keeping your heart and blood vessels in good condition. Even walking every day will help.
• eat well and lower the salt in your diet – aim to eat plenty of fruit and veg, wholegrains, fat-free or low-fat dairy products and lean proteins. Eating too much salt is the biggest cause of high blood pressure – the more salt you eat, the higher your blood pressure will be.
• deal with stress – when you’re anxious or upset, your heart beats faster, you breathe more heavily and your blood pressure often goes up. This can make heart failure worse too. Finding ways to cope with stress will help to keep your blood pressure down.

instructions for use, composition of Corega tablets

Corega Denture Cleaner Tablets: Deep cleansing for better denture hygiene :

^2,3,4

• mouth and gum irritation ⁵ ;
• bad breath ⁶ ;
• denture stomatitis ⁵ .

*Based on laboratory testing. Candida albicans species, soaked in solution for 5 minutes

Recommend Corega denture cleaner tablets for thorough cleaning with minimal possible damage to dentures

Dentures are about ten times softer than natural teeth (tooth enamel). ⁷ To maintain the functionality of a denture, it is important to use a product that will keep it clean without damaging the material.

Corega denture cleaning tablets contain four active ingredients that, working simultaneously, ensure proper denture hygiene with minimal scratches: ^1.8

1. Potassium monopersulfate
2. Sodium percarbonate
3. Tetraacetylethylenediamine (TAED)
4. Sodium lauryl sulfate (SLS)

Four active ingredients working simultaneously

Corega Denture Cleaner Tablets contain four active ingredients that work together to ensure proper denture hygiene with minimal scratches ^1.8

More articles on oral care in our learning materials.

Learn more

• Denture cleaning tablets Corega Bio Formula

  Composition

  Sodium Bicarbonate, Citric Acid, Potassium Caroate (Potassium Monopersulfate), Sodium Carbonate, Sodium Carbonate Peroxide, TAED, Sodium Benzoate, PEG-180, Sodium Lauryl Sulfate, VP/VA Copolymer, Aroma, Subtilisin, Cellulose Gum, CI 42090, CI 73015.

  Instructions for use

  1. Dip one Corega Bio Formula tablet in warm (not hot) water so that the resulting solution completely covers the denture.
  2. After 3-5 minutes, clean the denture with a soft brush using a solution such as Corega Denture Brush
  3. Rinse the prosthesis thoroughly under running water.
  4. Solution remaining after use should be discarded immediately.

  Special instructions

  Causes severe eye irritation. Wash hands thoroughly after use.

  IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if you wear them and if it is easy to do so. Continue rinsing eyes. If eye irritation persists, seek medical attention. Keep out of the reach of children and persons who, through negligence, can swallow a tablet or solution.

  IF SWALLOWED: Seek immediate medical attention. If irritation occurs, discontinue use and consult a physician. — Contains PEPPERMINT OIL, SUBTILYSIN. An allergic reaction is possible.

• Denture Cleaner Tablets Corega Whitening

  Composition

  Sodium Bicarbonate, Citric Acid, Potassium Caroate (Potassium Monopersulfate), Sodium Carbonate Peroxide, Sodium Carbonate, TAED, Sodium Benzoate, PEG-180, Sodium Lauryl Sulfate, Aroma, VP/VA Copolymer, CI 42090, CI 73015

  Instructions for use

  1. Dip one tablet of Corega Whitening in warm (not hot) water so that the resulting solution completely covers the denture.
  2. After 3-5 minutes, clean the denture with a soft brush using a solution such as Corega Denture Brush
  3. Rinse the prosthesis thoroughly under running water. The solution remaining after use should be discarded immediately.

  Special instructions

  Do not put the tablet or solution into the mouth. Do not use if hypersensitive to any of the ingredients. Do not use the solution for cleansing inside and do not use as a mouth rinse. During the use of tablets or solution, avoid contact with the mouth and eyes. Harmful if swallowed. Causes serious eye irritation. May cause an allergic reaction. Wash your hands thoroughly after handling the substance

  IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if you wear them and if it is easy to do so. Continue rinsing eyes. If eye irritation persists, seek medical attention. Keep out of the reach of children and persons who, through negligence, can swallow a tablet or solution.

  IF SWALLOWED: Seek immediate medical attention. If irritation occurs, discontinue use and consult a physician.

Corega Cleansing mouth guards and retainers 30 pcs

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Attention! The price of the goods is valid only when placing an order on the website

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– 20% for 2pack

The appearance of the product may differ from the image

Product code:
252272

Manufacturer:
GlaxoSmith Kline Healthcare

Country of origin:
Ireland

Release form:
Tablets

Dispensing order:
OTC

Contraindications, consult your doctor

20% discount when buying two packs. The discount is available at the checkout.

Payment and methods of receipt

Price:

399 ₽

+8 bonuses

The price is valid only when ordering on the site

There are contraindications, consult a doctor

Manufacturer:
GlaxoSmith Kline Healthcare

Country of origin:
Ireland

Release form:
Tablets

Dispensing order:
Without prescription

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Prices for Corega Tablets cleaning mouth guards and retainers 30 pcs and the availability of goods in pharmacies GORZDRAV in Moscow and the Moscow region

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You can buy Corega Tablets cleaning mouth guards and retainers 30 pcs at a price of 399 ₽ in GORZDRAV pharmacies in Moscow and Moscow region

Feature

Feature

Information

Instructions for use

Description

Corega is a set of denture care products designed for the convenience of using dentures and maintaining oral health.
Cleanliness and freshness of the mouth make you feel more confident when communicating with people, so it is important to understand how to properly care for dentures. Because dentures are approximately 10 times softer than natural teeth*, our specialized denture cleaners are formulated with a non-abrasive formula that is 9 times9.99% reduces the bacteria that cause bad breath** and, when used correctly, helps remove plaque and stubborn stains. You will be able to communicate more freely with those close to you and live a more fulfilling life.
Tablets for cleaning dentures Korega. Corega tablets reduce the number of bacteria and remove complex dirt and plaque from the surface of the prosthesis, while they are safe for regular use, they gently clean the denture, compared to cleaning with ordinary toothpaste. Corega tablets are a powerful tool that gently cleans dentures and effectively removes bacteria. Using Corega Tablets keeps your dentures fresh and clean. With their help, you can eat, speak and smile with confidence.
Corega Mouthguards & Retainers with Crystal Clear Technology A mild, abrasive-free formula that kills bacteria, removes stains, restores natural color and helps keep your removable orthodontic appliances clean.

Presentation

Tablets

Composition

SodiumBicarbonate, Citric Acid, PotassiumCaroate (PotassiumMonopersulfate), SodiumCarbonate, Carbon Sodiumate Peroxide, TAED , Sodium Benzoate, PEG-180, Sodium Lauryl Sulfate, VP/VA Copolymer, Aroma, Subtilisin, Cellulose Gum, Sodium Nitrite, CI 42090, CI 73015

Indications

Daily cleaning of aligners, retainers, sports mouthguards, teeth whitening mouthguards, night mouthguards, splint mouthguards, removable orthodontic brackets and plates

Contraindications

Individual intolerance to the components, pregnancy, breast-feeding. Before use, it is recommended to consult a doctor.

Special instructions

Do not take tablets or solution by mouth. Do not drink the solution for cleaning removable orthodontic appliances and do not use as a mouth rinse. Avoid contact with the mouth or eyes while using the tablets or solution. Do not use if you have a sensitivity to any of the ingredients in the product.

Q&A

How are your drugs stored?

Any goods provided by our pharmacy chain are stored in compliance with the necessary requirements and retain their quality. You can view supporting documents if you wish.

Does your network of pharmacies have loyalty programs for pensioners?

Yes, we have additional discounts and bonuses for pensioners and people over 55 years old. Moreover, our network is a participant of the program “Social longevity” from the Union of Pensioners of Russia. We organize sports days, master classes, lectures on health and its maintenance, and other events.

Your operator did not answer my question about the drug and its contraindications, said that it was not in his competence.