About all

Zertalin 500 mg: Complete Guide to Uses, Dosage, Side Effects, and Warnings

What are the primary uses of Zertalin 500 mg. How should it be dosed for various infections. What are the potential side effects and warnings associated with Zertalin 500 mg. How does Zertalin 500 mg compare to other antibiotics.

Understanding Zertalin 500 mg: An Overview of This Powerful Antibiotic

Zertalin 500 mg, also known by its generic name azithromycin, is a versatile antibiotic belonging to the macrolides class. First approved by the Food and Drug Administration (FDA) in 1991, this medication has become a cornerstone in treating various bacterial infections. Its effectiveness against a wide range of bacteria, particularly those in the Streptococcus family, has made it a preferred choice for many healthcare providers.

How does Zertalin 500 mg work. This antibiotic functions by inhibiting bacterial growth, effectively halting the progression of infections. It’s important to note that Zertalin is not effective against viral infections and should not be used as a pain reliever. As with all antibiotics, proper use is crucial to prevent the development of antibiotic-resistant bacteria.

Key Uses of Zertalin 500 mg: Targeting Specific Bacterial Infections

Zertalin 500 mg is prescribed for a variety of mild to moderate infections affecting different parts of the body. Healthcare professionals often turn to this medication when treating conditions of the lungs, sinuses, skin, and other areas. Let’s explore some of the primary uses of Zertalin 500 mg:

  • Sinus infections caused by Moraxella catarrhalis or Streptococcus pneumoniae
  • Community-acquired pneumonia related to Chlamydia pneumoniae, Haemophilus influenzae, or S. pneumoniae
  • Chronic obstructive pulmonary disease (COPD) complications linked to M. catarrhalis or S. pneumoniae
  • Certain skin infections associated with Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae
  • Tonsillitis caused by S. pyogenes
  • Urethritis and cervicitis related to Chlamydia trachomatis
  • Chancroid genital ulcers in males, caused by Haemophilus ducreyi
  • Specific ear infections in children aged 6 months and older, such as those related to M. catarrhalis

Why is Zertalin 500 mg effective against such a diverse range of infections. Its broad-spectrum activity allows it to target multiple bacterial species, making it a versatile choice for healthcare providers. However, it’s crucial to remember that Zertalin is a prescription medication and should only be taken under the guidance of a qualified healthcare professional.

Dosage Guidelines: Ensuring Optimal Efficacy of Zertalin 500 mg

The appropriate dosage of Zertalin 500 mg varies depending on the type and severity of the infection being treated. Available in tablet form, oral suspension solution, eye drops, and injectable formulations, the medication offers flexibility in administration. Patients can take Zertalin with or without food, but it’s essential to shake the liquid form thoroughly before use.

Here are some common dosage examples for various infections:

  • Community-acquired pneumonia, tonsillitis, and skin infections: An initial dose of 500 mg followed by 250 mg once daily until day 5
  • Mild-to-moderate bacterial COPD exacerbations: 500 mg per day for 3 days, or an initial dose of 500 mg followed by 250 mg once daily until day 5
  • Sinus infections: 500 mg per day for 3 days
  • Chancroid genital ulcers: A single dose of 1 gram (g)
  • Urethritis and cervicitis: A single dose of 1 g
  • Gonococcal urethritis and cervicitis: A single dose of 2 g

How can patients ensure they’re taking Zertalin 500 mg correctly. It’s crucial to follow the prescribed dosage and complete the entire course of antibiotics, even if symptoms improve before the medication is finished. This practice helps prevent the development of antibiotic-resistant bacteria.

Potential Side Effects: What to Watch for When Taking Zertalin 500 mg

While Zertalin 500 mg is generally well-tolerated, like all medications, it can cause side effects in some individuals. In clinical trials, only 0.7% of participants discontinued Zithromax (the brand name for azithromycin) due to adverse effects. Most side effects are minor and often resolve on their own, but it’s important to be aware of potential reactions.

Common side effects of Zertalin 500 mg include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain

Less common side effects, occurring in up to 1% of cases, may include:

  • Heart palpitations or chest pain
  • Acid reflux
  • Dizziness
  • Headache
  • Fatigue
  • Vaginitis
  • Rash
  • Dry skin
  • Sun sensitivity

When should patients be concerned about side effects. While rare, serious side effects can occur and may require immediate medical attention. These include:

  • Liver damage, particularly in individuals with a history of liver problems
  • Heart rhythm changes, more likely in older adults, those taking heart rhythm medications, or individuals with low blood potassium
  • Severe allergic reactions

Patients with myasthenia gravis, a condition causing muscle weakness, may experience worsening symptoms or breathing difficulties when taking Zertalin 500 mg. It’s crucial for individuals to inform their healthcare provider of any pre-existing conditions or medications before starting treatment with this antibiotic.

Important Warnings and Precautions for Zertalin 500 mg Use

While Zertalin 500 mg is an effective antibiotic for many bacterial infections, there are several important warnings and precautions to consider. Understanding these can help ensure safe and appropriate use of the medication.

Who should avoid taking Zertalin 500 mg. The antibiotic is contraindicated for:

  • Individuals with a history of allergic reactions to macrolides or ketolides
  • Patients with certain types of pneumonia, including those with cystic fibrosis, hospital-acquired infections, or bacteremia
  • People requiring hospitalization for pneumonia treatment
  • Older adults or debilitated individuals with pneumonia
  • Patients with significant underlying health problems, such as immune system disorders

Why is Zertalin 500 mg not recommended for treating syphilis. The antibiotic should not be relied upon for syphilis treatment, as it may not effectively combat this particular infection. Healthcare providers should consider alternative antibiotics for patients with suspected or confirmed syphilis.

Antibiotic Resistance: The Importance of Proper Zertalin 500 mg Usage

Antibiotic resistance is a growing concern in the medical community, and proper use of antibiotics like Zertalin 500 mg is crucial in combating this issue. When antibiotics are used incorrectly, it can lead to the development of drug-resistant bacterial strains, rendering these medications ineffective against future infections.

How can patients help prevent antibiotic resistance when taking Zertalin 500 mg. Here are some essential guidelines:

  1. Complete the entire prescribed course of antibiotics, even if symptoms improve before finishing the medication.
  2. Never take antibiotics without a prescription from a qualified healthcare provider.
  3. Avoid sharing antibiotics with others, as each prescription is tailored to a specific individual and infection.
  4. Follow the prescribed dosing schedule precisely, without altering the frequency or timing of doses.
  5. Contact a healthcare provider immediately if side effects develop or if there are concerns about the medication.
  6. Seek emergency medical attention for symptoms of an allergic reaction, such as difficulty breathing.

Why is antibiotic resistance a significant concern. When bacteria become resistant to antibiotics, it can lead to more severe infections, longer recovery times, and increased healthcare costs. By using antibiotics responsibly, patients can play a crucial role in preserving the effectiveness of these life-saving medications for future generations.

Zertalin 500 mg and Breastfeeding: Safety Considerations for Nursing Mothers

For nursing mothers, the safety of any medication is a top priority. Zertalin 500 mg is generally considered safe to use while breastfeeding, but it’s essential to discuss any concerns with a healthcare provider before starting treatment.

How does Zertalin 500 mg affect breastfeeding. The antibiotic does pass into breast milk in small amounts. However, studies have shown that these levels are typically too low to cause significant effects in nursing infants. Nevertheless, healthcare providers may recommend monitoring the infant for potential side effects, such as diarrhea or changes in feeding patterns.

When might a healthcare provider recommend against using Zertalin 500 mg while breastfeeding. In some cases, such as when treating a premature infant or a baby with liver or kidney problems, a doctor may suggest alternative antibiotics. It’s crucial for nursing mothers to provide a complete medical history for both themselves and their infants to ensure the safest possible treatment plan.

Potential Risks for Infants Exposed to Zertalin 500 mg Through Breast Milk

While the risk of adverse effects in breastfed infants is generally low, some potential concerns include:

  • Changes in the infant’s gut microbiome
  • Increased risk of thrush (oral yeast infection)
  • Temporary changes in stool consistency
  • Potential for antibiotic resistance development

How can nursing mothers minimize potential risks. Strategies may include:

  • Timing breastfeeding sessions to occur just before taking the medication
  • Monitoring the infant for any unusual symptoms or behavioral changes
  • Discussing alternative antibiotics with a healthcare provider if concerns arise

By working closely with healthcare providers and being vigilant about potential side effects, nursing mothers can safely use Zertalin 500 mg when necessary while minimizing risks to their infants.

Drug Interactions: Understanding Potential Risks with Zertalin 500 mg

As with any medication, Zertalin 500 mg can interact with other drugs, supplements, or even certain foods. These interactions may affect how the antibiotic works or increase the risk of side effects. It’s crucial for patients to inform their healthcare providers about all medications, supplements, and herbal products they are taking before starting treatment with Zertalin 500 mg.

Which medications are known to interact with Zertalin 500 mg. Some notable interactions include:

  • Antacids containing aluminum or magnesium: These may reduce the absorption of Zertalin 500 mg.
  • Blood thinners (e.g., warfarin): Zertalin may increase the blood-thinning effects of these medications.
  • Digoxin: Zertalin may increase digoxin levels in the blood, potentially leading to toxicity.
  • Nelfinavir: This HIV medication may increase Zertalin levels in the body.
  • Ergot alkaloids: Combining these with Zertalin can increase the risk of ergot toxicity.
  • Statins: There may be an increased risk of muscle-related side effects when taken with Zertalin.

How can patients minimize the risk of drug interactions. Here are some strategies:

  1. Provide a complete list of all medications, supplements, and herbal products to healthcare providers.
  2. Inform pharmacists about all current medications when filling a Zertalin 500 mg prescription.
  3. Avoid starting new medications or supplements without consulting a healthcare provider during Zertalin treatment.
  4. Follow specific instructions regarding the timing of Zertalin doses in relation to other medications, particularly antacids.
  5. Report any unusual symptoms or side effects to a healthcare provider promptly.

Why is it essential to be aware of potential drug interactions. Understanding these interactions can help prevent adverse effects, ensure the effectiveness of all medications being taken, and contribute to overall patient safety. By staying informed and communicating openly with healthcare providers, patients can maximize the benefits of Zertalin 500 mg while minimizing potential risks.

Special Considerations for Patients with Heart Conditions

Patients with pre-existing heart conditions require special attention when considering treatment with Zertalin 500 mg. The antibiotic has been associated with rare cases of heart rhythm changes, particularly in individuals with certain risk factors.

Which heart conditions warrant extra caution with Zertalin 500 mg. Patients with the following conditions should discuss the risks and benefits of Zertalin use with their healthcare providers:

  • Congenital long QT syndrome
  • Bradyarrhythmias
  • Uncompensated heart failure
  • History of Torsades de Pointes

How can healthcare providers mitigate risks for patients with heart conditions. Strategies may include:

  • Conducting a thorough cardiac evaluation before prescribing Zertalin 500 mg
  • Considering alternative antibiotics for high-risk patients
  • Monitoring electrolyte levels, particularly potassium and magnesium
  • Advising patients to report any symptoms of irregular heartbeat or palpitations immediately

By carefully assessing individual patient risk factors and closely monitoring those with heart conditions, healthcare providers can help ensure the safe and effective use of Zertalin 500 mg across a diverse patient population.

Uses, dosage, side effects, and warnings

Azithromycin (Zithromax) is an antibiotic that can help treat certain bacterial infections. It is generally safe to use while breastfeeding, but people with existing heart conditions should avoid this drug.

Azithromycin is an antibiotic in the macrolides class. The Food and Drug Administration (FDA) first approved azithromycin in 1991.

Like all antibiotics, azithromycin can only fight certain bacteria. For this reason, it is important to talk to a doctor before taking the drug. It is not effective against viral infections or as a pain reliever.

This article provides an overview of azithromycin, including its uses, side effects, warnings, and drug interactions.

Share on PinterestA doctor may prescribe azithromycin for a sinus infection, COPD complications, or tonsillitis, for example.

Azithromycin can fight a wide range of bacteria, including many in the Streptococcus family. It can stop harmful bacteria from growing.

Healthcare providers tend to use this drug to treat mild-to-moderate infections of the lungs, sinuses, skin, and other body parts.

A doctor may prescribe azithromycin to treat the following bacterial infections:

  • sinus infections related to Moraxella catarrhalis or Streptococcus pneumoniae
  • community-acquired pneumonia related to Chlamydia pneumoniae, Haemophilus influenzae, or S. pneumoniae
  • chronic obstructive pulmonary disease (COPD) complications related to M. catarrhalis or S. pneumoniae
  • some skin infections related to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae
  • tonsillitis related to S. pyogenes
  • urethritis and cervicitis related to Chlamydia trachomatis
  • chancroid genital ulcers (in males) related to Haemophilus ducreyi
  • certain ear infections in children aged 6 months and over, such as those related to M. catarrhalis

Azithromycin is a prescription medication. Therefore, people should not take it without a prescription.

The drug is available in the form of a tablet, an oral suspension solution, an eye drop, and an injection. The best type and dosage depends on the infection a person has.

People can take the drug with or without food. They should thoroughly shake the liquid form before use.

Some examples of common dosages include:

InfectionDosage
community-acquired pneumonia
tonsillitis
skin infections
an initial dose of 500 milligrams (mg) followed by 250 mg once daily until day 5
mild-to-moderate bacterial COPD exacerbations500 mg per day for 3 days
OR
an initial dose of 500 mg followed by 250 mg once daily until day 5
sinus infections500 mg per day for 3 days
chancroid genital ulcersa single dose of 1 gram (g)
urethritis
cervicitis
a single dose of 1 g
gonococcal urethritis
cervicitis
a single dose of 2 g

Using antibiotics incorrectly can lead to the development of drug-resistant strains of bacteria, meaning that antibiotics no longer work against them. This is called antibiotic resistance.

When taking azithromycin or any other antibiotic, people should heed the following precautions:

  • Take the entire course of antibiotics the doctor recommends, even when starting to feel better.
  • Do not take antibiotics without a prescription. Not all antibiotics can treat all bacteria.
  • Do not share antibiotics.
  • Do not take antibiotics on a different dosing schedule than the one a doctor prescribes.
  • Immediately call a doctor if side effects develop.
  • Go to the emergency room for symptoms of an allergic reaction, such as trouble breathing.

Learn more about antibiotic resistance here.

Share on PinterestSide effects of azithromycin may include nausea and vomiting.

Like all drugs, azithromycin can have certain side effects. These are usually minor. In clinical trials, only 0.7% of people stopped taking Zithromax because of its side effects.

Most of the side effects that led people to stop taking the drug were gastrointestinal, such as:

  • nausea
  • vomiting
  • diarrhea
  • pain in the abdomen

Less common side effects, occurring in up to 1% of cases, include:

  • heart palpitations or chest pain
  • acid reflux
  • dizziness
  • headache
  • fatigue
  • vaginitis
  • a rash
  • dry skin
  • sun sensitivity

Serious side effects are rare but can include:

  • liver damage, especially in people with a history of liver health problems
  • heart rhythm changes, which are more likely in people who take heart rhythm medications, older people, and those with low blood potassium
  • serious allergic reactions

People who have myasthenia gravis, a condition that causes muscle weakness, may develop worsening symptoms or breathing problems.

People with a history of allergic reactions to macrolides or ketolides should not take azithromycin.

Doctors should not prescribe this drug to treat pneumonia if a person:

  • has cystic fibrosis
  • has a hospital-acquired infection
  • has bacteremia
  • requires a stay in the hospital
  • is older or debilitated
  • has a significant underlying health problem, such as immune system problems

People should not rely on azithromycin to treat syphilis.

A person should speak to a doctor about any existing heart, kidney, and liver conditions before taking azithromycin, including an irregular heartbeat and especially QT prolongation.

What does the research say?

A large 2012 cohort study found a small increase in the risk of cardiovascular death among people taking azithromycin. The risk was higher among those with other risk factors for heart disease, such as smoking, low physical activity levels, and a high body mass index (BMI).

The study reported that when compared with amoxicillin, there were 47 additional cardiovascular deaths per 1 million azithromycin prescriptions. Among people with the highest risk of heart disease, there were 245 more deaths per 1 million courses of azithromycin.

This suggests that other antibiotics, such as amoxicillin, may be a safer option for people with heart disease or certain types of heart arrythmias.

In 2018, the FDA issued a warning about the long term use of azithromycin in people with certain blood or lymph node cancers who have stem cell transplants. Emerging research has suggested that azithromycin may increase the risk of cancer relapse in these people.

Following a stem cell transplant, some people take azithromycin to reduce the risk of an inflammatory lung condition called bronchiolitis obliterans syndrome. The FDA have not approved azithromycin for this use, however.

Rarely, azithromycin can cause liver toxicity. People should stop taking the drug and call their doctor if they develop any symptoms of liver problems, including dark urine, itching, or yellow eyes.

In newborns younger than 42 days old, azithromycin may cause a dangerous condition called infantile hypertrophic pyloric stenosis. Caregivers should contact a doctor if a baby becomes irritable or vomits when eating.

Azithromycin may interact with other medications a person is taking.

For example, using azithromycin while taking nelfinavir, which is a drug that helps treat HIV, can increase the risk of liver abnormalities and hearing problems.

Azithromycin can also increase the effects of blood thinners such as warfarin.

Other drugs that may interact with azithromycin include:

  • digoxin, a heart medication
  • colchicine, a gout medication
  • phenytoin, a seizure medication
  • antacids that contain magnesium or aluminum

A person should tell a doctor about all current medications, supplements, and remedies before taking azithromycin. Always speak to a doctor before stopping taking medications.

Share on PinterestA person may take azithromycin while breastfeeding but should discuss it with a healthcare professional first.

Azithromycin may be safe to use during pregnancy and while breastfeeding.

Studies of animals who received very large doses of azithromycin did not find an increased risk of miscarriage or birth defects.

However, there have been no high quality studies in pregnant humans, so the drug label currently states that “azithromycin should be used during pregnancy only if clearly needed.”

Azithromycin can transfer into breast milk and may remain present for 48 hours following a person’s last dose. Although it is generally safe to use when breastfeeding, azithromycin may cause diarrhea, vomiting, or a rash in some babies.

A person should tell a doctor if they are pregnant, might be pregnant, or are breastfeeding before taking azithromycin. If a nursing infant develops side effects while the parent is taking azithromycin, call a doctor for advice.

The brand name version of azithromycin (Zithromax) is typically more expensive than the generic version.

However, the price may vary depending on the pharmacy, a person’s insurance coverage and deductibles, and their geographic location.

Azithromycin treats many of the same infections that drugs such as penicillin and amoxicillin can treat.

A doctor may prescribe azithromycin as an alternative to other antibiotics because it typically requires a shorter course. It is also a good option for people with a history of allergies to other medications, or when other antibiotics do not work.

Because the risk of heart health problems is higher with azithromycin than with some other antibiotics, people with heart disease or arrhythmias should ask their doctor about trying a different antibiotic.

Azithromycin is an antibiotic that can treat many types of bacterial infection. It can also prevent these infections from getting worse or spreading.

Like all antibiotics, it presents some risks, so it is important to only take it under the guidance of a medical professional.

Uses, dosage, side effects, and warnings

Azithromycin (Zithromax) is an antibiotic that can help treat certain bacterial infections. It is generally safe to use while breastfeeding, but people with existing heart conditions should avoid this drug.

Azithromycin is an antibiotic in the macrolides class. The Food and Drug Administration (FDA) first approved azithromycin in 1991.

Like all antibiotics, azithromycin can only fight certain bacteria. For this reason, it is important to talk to a doctor before taking the drug. It is not effective against viral infections or as a pain reliever.

This article provides an overview of azithromycin, including its uses, side effects, warnings, and drug interactions.

Share on PinterestA doctor may prescribe azithromycin for a sinus infection, COPD complications, or tonsillitis, for example.

Azithromycin can fight a wide range of bacteria, including many in the Streptococcus family. It can stop harmful bacteria from growing.

Healthcare providers tend to use this drug to treat mild-to-moderate infections of the lungs, sinuses, skin, and other body parts.

A doctor may prescribe azithromycin to treat the following bacterial infections:

  • sinus infections related to Moraxella catarrhalis or Streptococcus pneumoniae
  • community-acquired pneumonia related to Chlamydia pneumoniae, Haemophilus influenzae, or S. pneumoniae
  • chronic obstructive pulmonary disease (COPD) complications related to M. catarrhalis or S. pneumoniae
  • some skin infections related to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae
  • tonsillitis related to S. pyogenes
  • urethritis and cervicitis related to Chlamydia trachomatis
  • chancroid genital ulcers (in males) related to Haemophilus ducreyi
  • certain ear infections in children aged 6 months and over, such as those related to M. catarrhalis

Azithromycin is a prescription medication. Therefore, people should not take it without a prescription.

The drug is available in the form of a tablet, an oral suspension solution, an eye drop, and an injection. The best type and dosage depends on the infection a person has.

People can take the drug with or without food. They should thoroughly shake the liquid form before use.

Some examples of common dosages include:

InfectionDosage
community-acquired pneumonia
tonsillitis
skin infections
an initial dose of 500 milligrams (mg) followed by 250 mg once daily until day 5
mild-to-moderate bacterial COPD exacerbations500 mg per day for 3 days
OR
an initial dose of 500 mg followed by 250 mg once daily until day 5
sinus infections500 mg per day for 3 days
chancroid genital ulcersa single dose of 1 gram (g)
urethritis
cervicitis
a single dose of 1 g
gonococcal urethritis
cervicitis
a single dose of 2 g

Using antibiotics incorrectly can lead to the development of drug-resistant strains of bacteria, meaning that antibiotics no longer work against them. This is called antibiotic resistance.

When taking azithromycin or any other antibiotic, people should heed the following precautions:

  • Take the entire course of antibiotics the doctor recommends, even when starting to feel better.
  • Do not take antibiotics without a prescription. Not all antibiotics can treat all bacteria.
  • Do not share antibiotics.
  • Do not take antibiotics on a different dosing schedule than the one a doctor prescribes.
  • Immediately call a doctor if side effects develop.
  • Go to the emergency room for symptoms of an allergic reaction, such as trouble breathing.

Learn more about antibiotic resistance here.

Share on PinterestSide effects of azithromycin may include nausea and vomiting.

Like all drugs, azithromycin can have certain side effects. These are usually minor. In clinical trials, only 0.7% of people stopped taking Zithromax because of its side effects.

Most of the side effects that led people to stop taking the drug were gastrointestinal, such as:

  • nausea
  • vomiting
  • diarrhea
  • pain in the abdomen

Less common side effects, occurring in up to 1% of cases, include:

  • heart palpitations or chest pain
  • acid reflux
  • dizziness
  • headache
  • fatigue
  • vaginitis
  • a rash
  • dry skin
  • sun sensitivity

Serious side effects are rare but can include:

  • liver damage, especially in people with a history of liver health problems
  • heart rhythm changes, which are more likely in people who take heart rhythm medications, older people, and those with low blood potassium
  • serious allergic reactions

People who have myasthenia gravis, a condition that causes muscle weakness, may develop worsening symptoms or breathing problems.

People with a history of allergic reactions to macrolides or ketolides should not take azithromycin.

Doctors should not prescribe this drug to treat pneumonia if a person:

  • has cystic fibrosis
  • has a hospital-acquired infection
  • has bacteremia
  • requires a stay in the hospital
  • is older or debilitated
  • has a significant underlying health problem, such as immune system problems

People should not rely on azithromycin to treat syphilis.

A person should speak to a doctor about any existing heart, kidney, and liver conditions before taking azithromycin, including an irregular heartbeat and especially QT prolongation.

What does the research say?

A large 2012 cohort study found a small increase in the risk of cardiovascular death among people taking azithromycin. The risk was higher among those with other risk factors for heart disease, such as smoking, low physical activity levels, and a high body mass index (BMI).

The study reported that when compared with amoxicillin, there were 47 additional cardiovascular deaths per 1 million azithromycin prescriptions. Among people with the highest risk of heart disease, there were 245 more deaths per 1 million courses of azithromycin.

This suggests that other antibiotics, such as amoxicillin, may be a safer option for people with heart disease or certain types of heart arrythmias.

In 2018, the FDA issued a warning about the long term use of azithromycin in people with certain blood or lymph node cancers who have stem cell transplants. Emerging research has suggested that azithromycin may increase the risk of cancer relapse in these people.

Following a stem cell transplant, some people take azithromycin to reduce the risk of an inflammatory lung condition called bronchiolitis obliterans syndrome. The FDA have not approved azithromycin for this use, however.

Rarely, azithromycin can cause liver toxicity. People should stop taking the drug and call their doctor if they develop any symptoms of liver problems, including dark urine, itching, or yellow eyes.

In newborns younger than 42 days old, azithromycin may cause a dangerous condition called infantile hypertrophic pyloric stenosis. Caregivers should contact a doctor if a baby becomes irritable or vomits when eating.

Azithromycin may interact with other medications a person is taking.

For example, using azithromycin while taking nelfinavir, which is a drug that helps treat HIV, can increase the risk of liver abnormalities and hearing problems.

Azithromycin can also increase the effects of blood thinners such as warfarin.

Other drugs that may interact with azithromycin include:

  • digoxin, a heart medication
  • colchicine, a gout medication
  • phenytoin, a seizure medication
  • antacids that contain magnesium or aluminum

A person should tell a doctor about all current medications, supplements, and remedies before taking azithromycin. Always speak to a doctor before stopping taking medications.

Share on PinterestA person may take azithromycin while breastfeeding but should discuss it with a healthcare professional first.

Azithromycin may be safe to use during pregnancy and while breastfeeding.

Studies of animals who received very large doses of azithromycin did not find an increased risk of miscarriage or birth defects.

However, there have been no high quality studies in pregnant humans, so the drug label currently states that “azithromycin should be used during pregnancy only if clearly needed.”

Azithromycin can transfer into breast milk and may remain present for 48 hours following a person’s last dose. Although it is generally safe to use when breastfeeding, azithromycin may cause diarrhea, vomiting, or a rash in some babies.

A person should tell a doctor if they are pregnant, might be pregnant, or are breastfeeding before taking azithromycin. If a nursing infant develops side effects while the parent is taking azithromycin, call a doctor for advice.

The brand name version of azithromycin (Zithromax) is typically more expensive than the generic version.

However, the price may vary depending on the pharmacy, a person’s insurance coverage and deductibles, and their geographic location.