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Clear eyes drops side effects: Clear Eyes Redness Relief: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Clear Eyes Redness Relief: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

How to use Clear Eyes Redness Relief Drops

Follow all directions on the product package, or use as directed by your doctor. If you have any questions, ask your doctor or pharmacist.

To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.

Remove contact lenses before applying the eye drops. Wait at least 10 minutes after using this medication before inserting contact lenses.

Before using, check this product visually. Do not use if the liquid has changed color or is cloudy. Use in affected eye(s) as directed.

Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over the eye and place 1 drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. Try not to blink and do not rub the eye. Repeat these steps if your dose is for more than 1 drop and for the other eye if so directed.

Do not rinse the dropper. Replace the dropper cap tightly after each use.

If you are using another kind of eye medication (such as drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.

Overuse of this type of medication may result in increased eye redness (rebound hyperemia). Tell your doctor if this occurs or if your condition lasts or gets worse after 48 hours. If you develop eye pain/vision changes or think you may have a serious medical problem, get medical help right away.

Side Effects

Stinging, redness, widened pupils, or blurred vision may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: eye pain, other vision problems, worsening redness/itching/swelling in or around the eyes, dizziness, nausea, sweating, drowsiness, weakness, nervousness, headache, decrease in body temperature, irregular heartbeat.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using naphazoline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as high blood pressure), glaucoma, diabetes, eye infection/injury, overactive thyroid (hyperthyroidism).

After you apply this drug, your vision may become temporarily blurred. This drug may also rarely make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Consult your pharmacist or physician.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does Clear Eyes Redness Relief Drops interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: drowsiness, decreased body temperature.

If your symptoms are due to allergies, avoid allergens that may be the cause of your symptoms. Some common causes of allergies include pollen, grasses, weeds, dust mites, and pet dander.

Keep all medical and lab appointments.

If this medication has been prescribed for you, use it for your current condition only. Do not use it later for another condition unless directed to do so by your doctor. A different medication may be necessary in that case.

If your doctor has directed you to use this medication on a regular schedule and you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light. Discard if drops become discolored or cloudy. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Clear Eyes Uses, Side Effects & Warnings

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Generic name: naphazoline ophthalmic [ na-FAZ-oh-leen-off-THAL-mik ]
Brand names: AK-Con, Albalon, Allersol, Clear Eyes, Clear Eyes + Redness Relief, Naphcon, Redness Relief Eye Drops
Drug class: Ophthalmic antihistamines and decongestants

Medically reviewed by Drugs.com on Feb 20, 2023. Written by Cerner Multum.

What is Clear Eyes?

Naphazoline is a vasoconstrictor. It works by narrowing swollen blood vessels in the eyes to reduce eye redness.

Clear Eyes (for the eye) is for temporary relief of minor eye redness or discomfort caused by minor irritants.

Clear Eyes may also be used for purposes not listed in this medication guide.

Warnings

Clear Eyes is for temporary relief of minor eye redness or discomfort caused by minor irritants.

You should not use Clear Eyes if you have narrow-angle glaucoma.

Stop using Clear Eyes and call your doctor at once if you have ongoing or worsening eye redness, eye pain, vision changes, severe dizziness, or headache, buzzing in your ears, or feeling short of breath.

Before taking this medicine

You should not use Clear Eyes if you are allergic to it, or if you have narrow-angle glaucoma.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

  • heart disease, high blood pressure;

  • diabetes;

  • a thyroid disorder; or

  • an eye injury or infection.

FDA pregnancy category C. It is not known whether Clear Eyes will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether naphazoline ophthalmic passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Clear Eyes?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Using the medication too long or too often may worsen your symptoms and cause damage to the blood vessels in your eyes.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

  • Close your eye and gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

  • Use only the number of drops recommended.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Since Clear Eyes is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of naphazoline ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Keep Clear Eyes out of the reach of children. Certain eye medications can cause serious medical problems in a young child who accidentally sucks on or swallows medicine from the eye dropper.

What should I avoid while using Clear Eyes?

Do not use this medication while wearing contact lenses. Clear Eyes may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Clear Eyes side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Clear Eyes may cause serious side effects. Stop using Clear Eyes and call your doctor at once if you have:

  • ongoing or worsening eye redness;

  • eye pain;

  • changes in your vision;

  • chest pain, fast or uneven heart rate; or

  • severe headache, buzzing in your ears, anxiety, confusion, or feeling short of breath.

Common side effects of Clear Eyes may include:

  • mild burning or stinging of the eye;

  • blurred vision, watery eyes; or

  • mild headache, dizziness, nervousness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Clear Eyes?

Ask a doctor or pharmacist if it is safe for you to use Clear Eyes if you are also using any of the following drugs:

  • an antidepressant–amitriptyline, clomipramine, desipramine, desvenlafaxine, doxepin, duloxetine, imipramine, maprotiline, milnacipran, nortriptyline, venlafaxine;

  • ergot medicine–ergotamine, dihydroergotamine, ergonovine, methylergonovine; or

  • an MAO inhibitor–furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine.

This list is not complete and other drugs may interact with Clear Eyes. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More about Clear Eyes Redness Relief (naphazoline ophthalmic)

  • Check interactions
  • Compare alternatives
  • Side effects
  • Drug class: ophthalmic antihistamines and decongestants

Patient resources

  • Drug Information
  • Redness Relief Eye Drops
  • Clear Eyes (Advanced Reading)
Other brands

Naphcon, AK-Con, Albalon, Allersol, … +2 more

Professional resources

  • Prescribing Information

Related treatment guides

  • Eye Redness

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 7.01.

Negative effects of eye drops

Find out about possible side effects of using eye drops, from allergic reactions to changes in eye color. Be careful when choosing drops and consult your doctor.

Eye drops are one of the most common treatments for eye conditions such as conjunctivitis, glaucoma, cataracts and many more. In addition, many people use eye drops to relieve various types of eye discomfort, such as itching, redness, tiredness, or irritation.

However, despite the widespread use of eye drops, these drugs can also cause negative effects on the eyes. In some cases, they can even worsen the condition of the eyes and lead to serious diseases.

Therefore, it is very important to be aware of the potentially harmful effects of eye drops in order to use them correctly and take care of your eyesight.

Corneal injury

The use of eye drops may cause adverse effects on the eyesight. In particular, the frequent use of drops can lead to damage to the cornea – a sclerotic, transparent part of the eye that does not have its own blood vessels, which plays a key role in the process of “contemplation” of the world.

With continued use of certain drops, side effects can often occur, such as changes in the shape or function of the cornea, which can lead to visual impairment. This is especially true of steroid drops that are used to treat eye inflammation, as they can damage the cornea, reducing its strength and increasing the risk of infection.

Some drops may also cause allergic reactions due to intolerance to a particular component of the drug. This can lead to severe itching and redness of the eyes, which in turn increases the chance of damage to the cornea. If you notice any changes in your vision or eye condition after using eye drops, contact your doctor to assess the possible risk of side effects and choose the drug that is best for you.

  • Do not use drops unless advised by a doctor
  • If side effects occur, consult a doctor
  • Corneal damage is a serious condition and requires mandatory medical attention treatment of certain eye diseases. However, care should be taken when using drops, as unwanted side effects can have serious consequences for eye vision and overall health.

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    Allergic reactions

    The use of eye drops may cause allergic reactions, especially in people prone to allergies. Such reactions can be caused both by the drops themselves and their ingredients.

    Symptoms of allergic reactions may include redness and itching of the eyes, swelling of the eyelids and conjunctiva. A runny nose, cough, difficulty breathing, and skin rashes may also occur.

    At the first sign of an allergic reaction, stop using the eye drops and consult a doctor. Treatment may include antihistamines and anti-inflammatory agents.

    Furthermore, people suffering from seasonal allergies should always consult their physician before using eye drops, as they may worsen their condition.

    In general, you need to be careful when using eye drops and only use them as directed by your doctor. At the first sign of an allergic reaction, stop using them immediately and seek medical attention.

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    Eye redness and burning

    Eye redness and burning are the most common adverse effects of eye drops. These symptoms may occur in most patients who use eye drops.

    Eye redness is usually caused by dilated capillaries that are on the surface of the eye. This symptom can also occur due to eye irritation or infection. In many cases, redness of the eyes is a response of the body to the composition of the eye drops. If the redness does not stop or the inflammation increases, you should immediately consult a doctor.

    Burning in the eyes usually occurs when the composition of the drops irritates the surface of the eye, and also when the person closes their eyes insufficiently while using the drops. The symptom may temporarily go away on its own. However, if the discomfort persists for several days, you should re-consult your doctor and consider replacing the eye drops with other drugs.

    If redness and burning in the eyes occur regularly, you should consult a doctor. He can prescribe additional treatment measures, as well as talk about prevention methods and what to do if unpleasant symptoms occur.

    Eyelid edema and watery eyes

    Eyelid edema is one of the possible side effects of eye drops. This causes swelling around the eyes, the skin becomes reddened and swollen. However, this effect is quite rare and soon disappears. If the edema becomes stable, you must immediately stop taking the drug.

    Lachrymation is another possible negative effect from the use of eye drops. It is expressed in a constant feeling of “wet” eyes, tears that can flow even in the absence of emotional arousal. This effect is also quite rare and soon disappears after drug withdrawal.

    It is worth noting that swelling and tearing can be caused not only by eye drops, but also by other drugs or an allergic reaction. If these symptoms appear, it is necessary to consult a doctor and exclude other possible causes.

    Impaired vision

    Eye drops may cause visual impairment. The fact is that some drops contain substances that can adversely affect eye health. For example, some redness drops contain decongestants that constrict blood vessels. This can impair the blood supply to the eyes and contribute to the appearance of farsightedness.

    In addition, frequent use of drops can lead to various side effects. For example, some drops contain preservatives that can cause allergic reactions or eye irritation. Other drops contain hormones or antibiotics that can interfere with the body’s natural self-regulation mechanism and contribute to infections and other diseases.

    • In addition, frequent use of eye drops can lead to dependence. With prolonged use of drops, side effects may develop, such as allergies or itching in the eyes.
    • It should also be borne in mind that improper use of the drops may lead to the fact that their effect is not achieved. Some people try to use the drops too often or in the wrong way, which can lead to poor vision.

    Therefore, if you experience vision problems or use eye drops frequently, you should consult your doctor. Only he can make the correct diagnosis and prescribe the appropriate treatment. In addition, the doctor can help you choose the most suitable drops and explain how to use them correctly.

    Headaches and dizziness

    Eye drops may cause headaches and dizziness in some people. This is due to the fact that the drops contain active substances that can affect the central nervous system.

    Headaches can occur both after incorrect use of the drops and after prolonged use. Often a headache occurs due to increased pressure inside the eye, which can cause vasodilation of the brain. Also, a headache may be associated with an allergic reaction to the components of the drops.

    Dizziness can also be caused by the use of eye drops. This may be due to changes in blood pressure and effects on the central nervous system. Often dizziness occurs when the drops are used incorrectly, for example, with excessive pressure on the eyeballs when instilled.

    • In case of headaches and dizziness, seek medical attention.
    • Before using eye drops, you should read the instructions and follow their recommendations.
    • It is important not to exceed the dose and duration of the drops, as indicated in the instructions.

    Impairment of color vision

    The negative effect of eye drops on color vision is manifested as a violation of the color sensitivity of the eyes.

    • One of the main drugs that cause color vision disorders are analgesics. They contain phenylpropanolamine, which can cause changes in the ability to perceive colors.
    • Other medicines that contain atropine, a pupillary constrictor, may change the color sensitivity of the eyes. These medicines can cause disturbances in the perception of the color red.
    • For some people, even eye drops from the group of “COG inhibitors” (ketorolac, for example) can affect color sensitivity.

    All these medicines should generally be prescribed by a doctor only after a thorough diagnosis and determination of the cause of the disease. Therefore, in order to avoid unforeseen and dangerous consequences, do not use eye drops without the appointment of a specialist.

    Flies before the eyes

    Flies before the eyes is one of the most common negative effects of eye drops. “Flies” are small moving points that can move from the front of the eye to the back.

    This effect can be caused by the relaxation of the vitreous body of the eye when using some eye drops, causing the particles inside the vitreous body to move, creating this sensation.

    The appearance of “flies” before the eyes can cause some discomfort when reading or working on a computer, and in some cases it can lead to loss of vision. In addition, this phenomenon may portend more serious vision problems, so it is important to see a doctor if it starts to happen regularly.

    • Some eye drops that can cause eye flies:
      1. Anterior eye drops
      2. Antibacterial eye drops
      3. Glucocorticosteroid eye drops
      4. Non-argon eye drops
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    In general, “flies” before the eyes are an undesirable effect of the use of eye drops, which can lead to various vision problems. Patients should carefully monitor the manifestations of this phenomenon and immediately consult a doctor if it occurs regularly.

    Eye pain

    Eye drops may cause eye pain. This can happen due to several reasons. First, some drops contain preservatives that can irritate eye tissues. This results in pain or discomfort in the eyes.

    Second, misuse of drops can also lead to eye pain. If the drops are given in the wrong amount or not at the right point, it can put extra strain on the eye muscles or even damage the eye.

    In addition, eye drops may mask more serious eye problems such as infection or damage. If eye pain is accompanied by other symptoms, such as redness, severe watering or itching, you should consult a doctor.

    In general, if eye drops cause eye pain or other problems, stop using them and consult your doctor. He may recommend preservative-free drop replacements, dosage changes, or other treatments if needed.

    Weakness and fatigue of the eyes

    Proper functioning of the eyes, without overwork and stress, is an important element of a healthy lifestyle and the successful conduct of business and personal affairs. However, the use of eye drops can lead to negative effects, such as weakness and eye fatigue.

    Eye drops may reduce the frequency of blinking, resulting in dry, itchy eyes. This can cause increased eye fatigue and loss of vision throughout the day. Also, some drops contain preservatives that can irritate the eyes and cause weakness.

    Frequent use of the drops may also lead to a false diagnosis of the disease, as symptoms of fatigue and weakness may recur if the drops are used incorrectly. In addition, drops can provoke the development of additional diseases and infections of the eyes, which can lead to a deterioration in vision in general.

    Therefore, before using eye drops, you should consult a specialist and read the instructions for use. Pay attention to the composition and contraindications, as well as the dosage and frequency of use of the drops.

    If you experience eye weakness and fatigue, it is best to discuss this with your doctor or ophthalmologist to find the most effective and safe method of treatment and prevention.

    Dry eye

    Dry eye is one of the most common side effects that can occur with eye drops. Drops that contain preservatives can cause a deterioration in the quality of the tear film and, as a result, lead to dry eyes.

    Dry eyes cause burning sensation, itching and discomfort. This can lead to increased excitation of pain receptors in the eye, which negatively affects visual function and quality of life. In addition, with dry eyes, the quality of vision deteriorates significantly, especially when working on a computer and reading for a long time.

    In order to prevent dry eyes, it is necessary to observe the correct mode of work and rest, reduce the time spent at the computer, humidify the room where the person is, and choose the right eye drops, which are best consulted by an ophthalmologist.

    • Limit computer or screen time.
    • Keep the room moist
    • Choose the right eye drops
    • Drink enough water to increase overall body hydration

    Gritty feeling in the eyes

    drops. Most often this happens after the use of products intended to treat dry eyes or calm inflammatory processes.

    Symptoms of discomfort in the eyes are similar to the presence of small grains of sand in the eye, which slide over the surface of the eye, causing discomfort, itching and burning. In most cases, this condition is not a serious problem, but the constant feeling of sand can lead to significant discomfort and a decrease in quality of life.

    The appearance of a feeling of sand in the eyes can be associated with various factors, including poor environment, long-term contact lens wear, malnutrition and hormonal imbalance. However, if such a condition occurs after the use of eye drops, then in most cases these drugs are the main cause of discomfort.

    If you experience these symptoms, you should consult an ophthalmologist to get a correct diagnosis and determine the possible causes of the problem. Do not self-medicate, as improperly selected drops can damage the eyes and aggravate the situation.

    Change in the shape of the pupils

    Eye drops may cause changes in the shape of the pupils. In some cases, this effect can lead to deterioration in visual acuity.

    When using the drops, both dilation and constriction of the pupils can be observed. Pupil dilation can lead to an increase in the amount of light entering the eyes. At the same time, constriction of the pupils can lead to a decrease in the amount of light and a decrease in visual acuity.

    Enlarged pupils can also increase the risk of developing glaucoma, which is a dangerous eye disease that causes visual impairment and possibly even blindness.

    In order to avoid the negative consequences of developing eye diseases, you should always follow the dosage when using eye drops, avoid transferring drops from one eye to another, and also make sure that the drops do not enter the bloodstream.

    Rapid development of cataracts

    Eye drops may cause the rapid development of cataracts , a disease that leads to visual impairment. In a cataract, the area of ​​the lens becomes cloudy, resulting in a “fogging” in front of the eyes.

    This can happen with steroid drops, which are used to treat allergic reactions and inflammation of the eyes. They help to reduce inflammation and pain, but excessive use of them can lead to accelerated destruction of the lens.

    Studies have shown that people who use steroid drops for more than 10-14 days have a significantly greater risk of developing cataracts than those who do not use steroid drops.

    In addition, eye drops containing preservatives such as benzalkonium chloride may also cause cataracts. Prolonged use of drops can lead to the accumulation of benzalkonium chloride in the tissues of the eye, and this can lead to chronic inflammation of the eyes and accelerated destruction of the lens.

    It is recommended to use eye drops only on the advice of a physician and avoid excessive use. In case of any side effects, you should immediately consult your doctor.

    Loss of focus

    One of the negative effects of eye drops is the loss of focus. This effect is especially noticeable in people with pre-existing vision problems such as nearsightedness or farsightedness.

    The eye drop may cause pupillary constriction, which may change the distance between the lenses of the eye, which may adversely affect general myopia. Under certain conditions, such as using the wrong dosage or prolonged use of drops, more serious problems can occur, such as a change in the shape of the cornea of ​​\u200b\u200bthe eye.

    A sharp loss of focus can lead to impaired overall visual acuity, as well as headaches and deterioration in the general condition of the eyes and vision. The best solution in this situation would be to immediately contact a doctor for advice and appropriate treatment.

    In addition, in order to prevent blurred focus when using eye drops, a number of rules should be observed: use drops only when necessary and on the recommendation of a doctor, dose drops correctly, do not use drops for a long time, and if necessary, stop using drops every few days.

    Decreased blinking and depletion of the lacrimal gland

    Eye drops are often used to relieve symptoms such as itching, redness and dry eyes. However, prolonged use of these drops can adversely affect the condition of the eyes.

    One of the negative effects of the use of eye drops is a decrease in the frequency of blinking. A person blinks his eyes to moisten the surface of the eye and protect it from external stimuli. Under the influence of drops, many people forget about the need to blink, which can lead to dryness and irritation of the eye surface. As a result, a secondary disorder of the lacrimal gland occurs.

    Lacrimal gland depletion is another consequence of the frequent use of eye drops. They contain chemicals that temporarily replace the tear film, reducing dryness on the surface of the eye. However, often these components affect the work of the lacrimal gland, and in the future, tears during the normal work of the gland cease to be released quickly enough and in sufficient quantities, which leads to various types of keratitis, proximity and cataracts with regular use.

    Therefore, do not use eye drops frequently. They should only be used on the advice of a doctor and not for a long time. Also, it is necessary to observe the blinking mode and perform simple gymnastic exercises for the eyes in order to improve blood circulation and nutrition of the eyes.

    Secondary eye infections

    When using eye drops, especially for a long time, many patients may experience a negative phenomenon – the development of a secondary eye infection. Secondary infections may arise due to the attraction of new pathogens or the growth of pathogenic microorganisms as a result of dysregulation of the microbiocene in the eye.

    Secondary infection may present as purulent conjunctivitis, blepharitis, chalazion, or keratitis. Such infections can lead to symptoms such as redness of the eyes, itching, watery eyes, blurred vision, etc.

    If you experience these symptoms, you should consult an ophthalmologist who will identify the causative agent of the infection and determine the choice of treatment, as well as take preventive measures to control the infection.

    To prevent secondary infections, it is important to prioritize hand hygiene and follow the instructions given by your doctor or on the medication package. Avoiding burrows and limiting the use of cosmetics will help reduce the risk of infection with pathogens.

    Q&A:

    What are the possible negative effects of eye drops?

    Although eye drops are a safe and effective drug, there may be some negative effects. In such cases, various types of allergic reactions, pain and discomfort in the eyes, redness of the sclera, a change in visual reaction, a violation of the contour of the visual field, fogging of the eyes and other dysfunctions may appear.

    How can I reduce the risk of negative effects from eye drops?

    To reduce the risk of negative consequences, it is necessary to strictly follow the instructions for using eye drops, do not use analogues of various drugs, and take care of contact lenses, as they can increase the body’s threshold for the penetration of various ingredients. In the presence of certain diseases such as cataracts, astigmatism, glaucoma, consultation with an ophthalmologist is necessary, since the use of eye drops in such cases should be very careful.

    Are eye drops addictive?

    Yes, some eye drops can be addictive. This is especially true for eye drops that contain mydriatics. With regular and prolonged use of drops containing mydriatics, the sensitivity of eye receptors decreases. Therefore, after stopping the use of drops, vision problems may occur, including difficulty in adapting to changing light conditions and eye muscle weakness.

    Can eye drops cause visual impairment?

    Yes, if the eye drops are used incorrectly or the medicine is chosen incorrectly, visual impairment can be observed. For example, if drops are used with an incorrect diagnosis, then the consequences can be extremely negative. In addition, the use of eye drops inappropriately or without the advice of a specialist can also lead to long-term visual impairment.

    Can eye drops be used to treat red eyes?

    Yes, eye drops containing urea, hexamethylenetetramine, zinc can be used to treat red eyes. However, it must be borne in mind that such drops, if used irregularly, can cause the opposite effect and worsen the condition of the eyes. If it becomes necessary to use eye drops to treat red eyes, you should consult an ophthalmologist to determine the causes of red eyes and choose the most appropriate drug.

    Can eye drops damage eye health?

    Yes, eye drops have a limited spectrum of activity and can only be used to treat certain conditions, such as conjunctivitis, glaucoma, cataracts, etc. Incorrect use can cause serious damage to eye health, including damage to the integrity of the eye vessels, convulsions, dizziness, and increased inflammation.

    How to choose the right eye drops?

    The choice of eye drop depends on the cause of the eye disease. First you need to contact an ophthalmologist who will select the most suitable drug. When choosing drops, it is necessary to take into account age, the presence of allergic reactions, features of vision. In addition, it is recommended to contact only well-known manufacturers of drops in order to exclude counterfeit and low-quality drugs from entering the market. 9Dexamethasone (eye drops) 02 Dexamethasone

    Dosage form

    Eye drops 1 mg/ml 10 ml

    Composition

    90 002 1 ml contains:

    active substance – dexamethasone sodium phosphate in terms of 100% dry matter 1.0 mg;

    excipients: boric acid, sodium tetraborate, disodium edetate, benzalkonium chloride, water for injection.

    Description

    Clear, colorless liquid 0060

    Preparations for the treatment of eye diseases. Anti-inflammatory drugs. Glucocorticosteroids. Dexamethasone. ATX code S01BA01

    Pharmacological properties

    Pharmacokinetics

    The ophthalmic bioavailability of dexamethasone after topical application to the eye of the drug was studied in patients who underwent cataract surgery. The maximum level of dexamethasone in the intraocular fluid, equal to approximately 30 ng/ml, was reached within 2 hours. Then there was a decrease in concentration with a half-life of 3 hours.

    Dexamethasone is excreted from the body by metabolism. Approximately 60% of the dose is excreted in the urine as 6-β-hydrohydexamethasone. No unchanged dexamethasone was found in the urine. The elimination half-life from plasma is relatively short – 3-4 hours. Dexamethasone is approximately 77-84% bound to serum albumin. Clearance ranges from 0.111 to 0.225 l / h / kg, the volume of distribution ranges from 0.576 to 1.15 l / kg. The bioavailability of dexamethasone when administered orally is approximately 70%.

    Pharmacodynamics

    Corticosteroids have an anti-inflammatory effect by inhibiting endothelial cell vascular adhesion molecules, cyclooxygenase I or II and releasing cytokines. As a result, the formation of inflammatory mediators is reduced and the adhesion of leukocytes to the vascular endothelium is inhibited, thus preventing their penetration into the inflamed tissues of the eye. Dexamethasone has a pronounced anti-inflammatory effect with reduced mineralocorticoid effects compared to some other steroids and is one of the most potent anti-inflammatory drugs.

    Indications

    • Treatment of steroid-sensitive non-infectious inflammatory and allergic conditions of the conjunctiva, cornea and anterior segment of the eye, including inflammatory reactions in the postoperative period.

    Dosage and administration

    Use in adults, including elderly patients.

    For severe or acute inflammation, instill 1-2 drops into the conjunctival sac of the affected eye(s) every 1-2 hours as initial therapy.

    In case of a positive effect, the dose should be reduced to 1-2 drops in the conjunctival sac of the affected eye(s) every 2-4 hours.

    The dose can then be reduced to 1 drop 3-4 times a day if this dose is sufficient to control inflammation.

    If the desired result is not achieved within 3-4 days, additional systemic or subconjunctival therapy may be prescribed.

    For chronic inflammation, the dose is 1 or 2 drops into the conjunctival sac of the affected eye(s) every 3 to 6 hours, or more often if needed.

    For allergies or minor inflammation, the dose is 1-2 drops into the conjunctival sac of the affected eye(s) every 3-4 hours until the desired effect is achieved.

    Duration of application varies from a few days to 2 weeks.

    Do not stop therapy prematurely (see section “Special Instructions” ).

    It is recommended to constantly monitor intraocular pressure.

    Careful eyelid closure or nasolacrimal occlusion is recommended after instillation. This reduces the systemic absorption of drugs injected into the eye, which reduces the chance of systemic side effects.

    If several topical ocular medicines are used at the same time, the interval between their use should be at least 5 minutes. Eye ointments should be applied last.

    Use in disorders of the liver and kidneys.

    Dexamethasone has not been studied in patients with kidney or liver disease. However, due to the low systemic absorption of dexamethasone after topical use of this drug, dose adjustment is not necessary.

    How to use.

    Shake well before use.

    To prevent contamination of the edge of the dropper and suspension, care must be taken not to touch the eyelid, adjacent areas or other surfaces with the edge of the dropper bottle.

    Attention! Do not screw cap tightly before use! Screw the bottle cap on as far as possible before first use. In this case, the spike, which is located on the inside of the cap, pierces the hole. Immediately before use, hold the vial with the drug in the palm of your hand to warm it to body temperature. Unscrew the cap, remove and, slightly pressing on the bottle body, drip the solution into the eye. After instillation of the drug, screw the cap tightly and store the drug according to the recommendations given in the instructions.

    Side effects

    From the immune system: hypersensitivity.

    From the nervous system: dysgeusia, dizziness, headache.

    On the part of the organs of vision: discomfort in the eyes, keratitis, conjunctivitis, keratoconjunctivitis sicca, corneal coloration, photophobia, blurred vision, itchy eyes, sensation of a foreign body in the eyes, increased lacrimation, unusual sensation in the eyes, scaling at the edges of the eyelids, eye irritation, eye hyperemia, increased intraocular pressure, decreased visual acuity, corneal erosion , eyelid ptosis, eye pain, mydriasis.
    Long-term use of topical corticosteroids in the eye can lead to an increase in eye pressure with subsequent damage to the optic nerve, deterioration in visual acuity and visual field impairment, as well as the formation of posterior subcapsular cataracts (see section “Oso b th instructions” ).

    Since the drug contains corticosteroids, in the presence of diseases leading to thinning of the cornea or sclera, the risk of perforation increases after prolonged use.

    Corticosteroids may reduce resistance to infections (see section “Special Instructions” ).

    Contraindications

    • hypersensitivity to the active substance or to any of the components of the preparation
    • acute untreated bacterial infections
    • acute superficial keratitis due to herpes simplex
    • vaccinia and varicella and other viral infections of the cornea and conjunctiva (excluding herpes zoster keratitis)
    • fungal diseases of the structures of the eye
    • mycobacterial infections of the eye
    • eye tuberculosis
    • children under 18 years of age
    • pregnancy and lactation

    Drug interactions

    No specific drug interaction studies have been conducted with Dexamethasone, eye drops.

    There are known cases of interaction associated with the systemic use of dexamethasone. However, the systemic absorption of dexamethasone from topical ophthalmic use is low, so the risk of drug interactions is minimal.

    When using more than one topical ophthalmic drug, the interval between doses should be at least 5 minutes.

    Special instructions

    • For ophthalmic use only.
    • Long-term use of topical corticosteroids in the eye can lead to ocular hypertension and/or glaucoma with subsequent damage to the optic nerve, visual acuity and visual field impairment, and posterior subcapsular cataract formation. Patients with prolonged use of corticosteroids locally in the eye should constantly and regularly monitor intraocular pressure.
    • Corticosteroids may reduce resistance to bacterial, viral, or fungal infection, interfere with the detection of such infections, and mask the clinical signs of infection by preventing the detection of antibiotic failure. With persistent formation of corneal ulcers, the possibility of a fungal infection in patients who have been or are being treated with corticosteroids should be considered. Treatment should be discontinued if a fungal infection occurs.
    • Corticosteroids applied topically to the eye may delay the healing of corneal wounds.
    • In the presence of diseases that lead to thinning of the cornea or sclera, topical corticosteroids have been known to cause perforation.
    • The drug should be used with extreme caution and only in combination with antiviral therapy in the treatment of stromal keratitis or uveitis caused by herpes simplex; it is necessary to periodically carry out biomicroscopy using a slit lamp.
    • It is not recommended to wear contact lenses during the treatment of inflammation of the eye.
    • In addition, this preparation contains benzalkonium chloride, which may cause eye irritation and is known to discolour soft contact lenses. Contact with soft contact lenses should be avoided. Patients should be warned to remove contact lenses before using Dexamethasone eye drops and wait 15 minutes after instillation before inserting contact lenses.
    • Treatment should not be discontinued prematurely, as abrupt discontinuation of topical treatment with high doses of steroids may cause re-inflammation of the eye.

    Pediatric use

    The efficacy and safety of the drug in children have not been established.

    Use during pregnancy and lactation

    Use of the drug during pregnancy is not recommended.

    Systemic administration of corticosteroids results in their appearance in human breast milk in quantities that may affect the child who is breastfed. However, with topical application of the drug, systemic manifestations are low. It is not known whether Dexamethasone passes into breast milk. A risk to a breastfed child cannot be excluded. Consideration should be given to temporarily stopping breastfeeding while using Dexamethasone or stopping/abstaining from drug therapy, given the potential benefit of the drug for the mother and the benefit of breastfeeding for the child.

    Features of the effect of the drug on the ability to drive vehicles and potentially dangerous mechanisms

    Dexamethasone does not affect or slightly affects the ability to drive vehicles or other mechanisms. As with other eye drops, temporary blurred vision or other visual disturbances may affect the ability to drive or use machines. If blurred vision occurs during instillation, the patient should wait until vision clears before driving or operating machinery.

    Overdose

    There are no reports of any severe systemic reactions due to drug overdose.

    In case of overdose when applied topically, rinse eye(s) with warm water to remove drug residue.

    There is no specific antidote for topical corticosteroids.

    Treatment is symptomatic.

    Presentation and packaging

    10 ml in polyethylene vials, sealed with caps.

    A self-adhesive label is attached to the vial.

    The bottle, together with the instructions for medical use, is placed in a cardboard box.

    Storage conditions

    Store in the original container between 2°C and 8°C.

    Keep out of reach of children.

    Shelf life

    3 years

    After opening the vial, the drug is valid for 28 days.

    Do not use after the expiry date which is stated on the package.

    Terms of dispensing from pharmacies

    By prescription

    Producer

    Farmak PJSC, Ukraine, 0408 0, Kiev, st. Frunze, 74.

    Registration certificate holder

    Farmak PJSC, Ukraine

    Name, address and contact details of the organization in the Republic of Kazakhstan that accepts claims from consumers regarding the quality of products (goods) and is responsible for post-registration monitoring of the safety of the medicinal product

    Representative Office of PJSC Farmak in the Republic of Kazakhstan

    9000 2 Republic of Kazakhstan, Almaty, index 050012, st.