What are the common side effects of Abreva. How does Docosanol Topical work for cold sores. When should you start using Abreva for best results. What precautions should be taken when using this medication.

What is Abreva and How Does It Work?

Abreva, also known by its generic name Docosanol Topical, is a medication used for the treatment of cold sores. This over-the-counter drug is designed to shorten the duration of cold sore outbreaks and alleviate associated symptoms.

The active ingredient, docosanol, works by preventing the cold sore virus from entering healthy skin cells. By creating a barrier, it effectively halts the spread of the virus and allows the affected area to heal more quickly.

When Should You Start Using Abreva?

For optimal results, it’s crucial to begin using Abreva at the first sign of a cold sore. Early symptoms may include tingling, itching, or burning sensations around the lips. Prompt application can significantly reduce the severity and duration of the outbreak.

Proper Application and Usage of Abreva

To ensure the effectiveness of Abreva, follow these guidelines:

• Wash your hands thoroughly before and after application
• Apply a thin layer to the affected area
• Gently rub the medication into the skin
• Use as directed, typically five times a day
• Continue treatment until the cold sore has healed completely

Can you apply makeup over Abreva? Yes, but wait until the medication has dried completely on the skin before applying any cosmetics.

Common Side Effects of Abreva

While Abreva is generally well-tolerated, some users may experience side effects. The most common include:

• Mild skin irritation
• Redness at the application site
• Burning or stinging sensation
• Itching
• Dryness or flaking of the skin

These side effects are typically mild and resolve on their own. However, if they persist or worsen, it’s advisable to consult a healthcare professional.

Serious Side Effects and When to Seek Medical Attention

Although rare, some individuals may experience more severe reactions to Abreva. Seek immediate medical attention if you notice any of the following:

1. Signs of an allergic reaction (rash, hives, itching, difficulty breathing, swelling of face, lips, tongue, or throat)
2. Severe skin irritation or burning at the application site
3. Unusual changes in the appearance of the cold sore or surrounding skin

Are there any long-term side effects of using Abreva? Current research suggests that long-term use of Abreva does not pose significant risks. However, as with any medication, it’s best to use it only as needed and as directed.

Precautions and Interactions with Abreva

Before using Abreva, consider the following precautions:

• Inform your healthcare provider about any allergies or sensitivities
• Discuss all current medications, including over-the-counter drugs and supplements
• Avoid using other topical products on the affected area unless directed by a doctor
• Do not use in children under 12 years old without consulting a pediatrician
• Exercise caution if pregnant or breastfeeding

Does Abreva interact with other medications? While Abreva is generally safe, it’s always best to consult with a healthcare provider or pharmacist about potential interactions with your current medications.

Proper Storage and Disposal of Abreva

To maintain the efficacy and safety of Abreva:

• Store at room temperature, away from direct sunlight and moisture
• Keep the tube tightly closed when not in use
• Do not freeze the medication
• Keep out of reach of children and pets
• Dispose of expired or unused medication properly, following local guidelines

How long can you keep an opened tube of Abreva? Once opened, Abreva typically remains effective for up to 12 months. However, always check the expiration date and discard if the appearance or consistency changes.

Tips for Managing Cold Sores Beyond Medication

While Abreva is effective in treating cold sores, complementary strategies can enhance healing:

• Maintain good hygiene to prevent spreading the virus
• Apply a cold compress to reduce swelling and discomfort
• Stay hydrated and maintain a balanced diet rich in vitamins
• Avoid triggers such as stress, excessive sun exposure, or certain foods
• Use lip balm with SPF to protect your lips from sun damage

Can lifestyle changes prevent cold sore outbreaks? While not foolproof, managing stress, maintaining a healthy immune system, and avoiding known triggers can significantly reduce the frequency of cold sore outbreaks.

Understanding Cold Sores and Their Causes

Cold sores, also known as fever blisters, are caused by the herpes simplex virus (HSV-1 or HSV-2). These small, fluid-filled blisters typically appear on or around the lips and can be painful and unsightly.

The Viral Life Cycle

The herpes virus follows a specific life cycle:

1. Initial infection: The virus enters the body through a break in the skin or mucous membranes
2. Latency period: The virus remains dormant in nerve cells
3. Reactivation: Triggered by various factors, the virus becomes active again
4. Outbreak: Symptoms appear, including tingling sensation and blisters
5. Healing: Blisters crust over and eventually heal

Why do some people get cold sores more frequently than others? Factors such as stress, hormonal changes, weakened immune system, and genetic predisposition can influence the frequency of outbreaks.

Comparing Abreva to Other Cold Sore Treatments

Abreva is one of several treatments available for cold sores. Let’s compare it to other options:

Is Abreva more effective than other over-the-counter treatments? Clinical studies have shown that Abreva can reduce healing time more effectively than many other OTC options, but individual results may vary.

The Science Behind Docosanol: How Abreva Works

Docosanol, the active ingredient in Abreva, is a long-chain saturated alcohol that works through a unique mechanism to combat cold sores:

1. Membrane fusion inhibition: Docosanol integrates into the cell membrane, making it difficult for the virus to fuse with and enter healthy cells
2. Viral spread prevention: By blocking entry into new cells, docosanol effectively limits the spread of the virus
3. Accelerated healing: With the virus unable to infect new cells, the body’s immune system can more effectively combat the existing infection

This mechanism differs from antiviral medications that work inside the cell to prevent viral replication.

The Effectiveness of Docosanol

Clinical studies have demonstrated the efficacy of docosanol in treating cold sores:

• Reduction in healing time: On average, cold sores treated with docosanol healed 17.5 hours faster than those treated with a placebo
• Symptom relief: Users reported quicker relief from pain, itching, and burning sensations
• Prevention of full breakouts: When applied at the first sign of a cold sore, docosanol can sometimes prevent the formation of a full blister

How quickly does Abreva start working? While individual responses vary, many users report feeling relief within the first 24 hours of application.

Navigating Cold Sore Myths and Facts

There are many misconceptions about cold sores. Let’s separate fact from fiction:

Myth: Cold sores are the same as canker sores

Fact: Cold sores are caused by a virus and appear on the outside of the mouth, while canker sores are non-contagious ulcers that occur inside the mouth.

Myth: You can only get cold sores through kissing

Fact: While kissing is a common transmission method, cold sores can also spread through sharing utensils, towels, or any item that comes into contact with the sore.

Myth: Once you have a cold sore, you’re always contagious

Fact: Cold sores are most contagious when blisters are present, but the virus can still spread even when no symptoms are visible.

Myth: Abreva can prevent you from ever getting cold sores

Fact: While Abreva can shorten the duration and severity of outbreaks, it cannot prevent initial infection or stop all future outbreaks.

Can you build immunity to cold sores over time? While the immune system becomes better at suppressing the virus, complete immunity is rare. However, outbreaks often become less frequent and severe with age.

The Psychological Impact of Cold Sores and How Abreva Can Help

Cold sores can have a significant psychological impact on sufferers, including:

• Embarrassment and self-consciousness
• Anxiety about social interactions
• Decreased self-esteem
• Stress, which can ironically trigger more outbreaks

Abreva can help alleviate these psychological effects by:

1. Reducing the duration of outbreaks, minimizing the time sufferers feel self-conscious
2. Providing a sense of control over the condition
3. Offering quick symptom relief, reducing stress associated with discomfort
4. Potentially preventing full breakouts when used early, boosting confidence

How can individuals cope with the emotional aspects of cold sores? Support groups, cognitive-behavioral therapy, and stress-reduction techniques can be helpful in managing the psychological impact of recurrent cold sores.

Future Developments in Cold Sore Treatment

Research into cold sore treatment continues to evolve. Some promising areas of development include:

• Gene editing techniques to potentially eliminate the virus from nerve cells
• New antiviral compounds that target different stages of the viral life cycle
• Immunotherapy approaches to boost the body’s natural defenses against the virus
• Improved delivery methods for existing medications to enhance efficacy

While Abreva remains a go-to treatment for many, these advancements may offer even more effective options in the future.

Could a cure for cold sores be on the horizon? While a complete cure remains elusive, ongoing research provides hope for more effective treatments and potentially a way to eliminate the virus entirely.

Maximizing the Benefits of Abreva: Best Practices

To get the most out of your Abreva treatment, consider these best practices:

1. Act fast: Apply at the first sign of a cold sore for best results
2. Be consistent: Follow the recommended application schedule
3. Keep it clean: Wash your hands before and after application to prevent spreading the virus
4. Don’t share: Use separate tubes for different family members to avoid cross-contamination
5. Combine treatments: Consider using Abreva alongside other doctor-recommended treatments for enhanced efficacy

Is it possible to use too much Abreva? While Abreva is generally safe, overuse can lead to skin irritation. Stick to the recommended dosage unless directed otherwise by a healthcare professional.

Tracking Your Outbreaks

Keeping a log of your cold sore outbreaks can be beneficial:

• Identify triggers by noting potential causes before each outbreak
• Monitor the effectiveness of Abreva by recording healing times
• Recognize patterns in outbreak frequency and severity
• Provide valuable information to your healthcare provider if needed

By understanding your personal cold sore patterns, you can better prepare for and manage future outbreaks, maximizing the benefits of Abreva and other treatments.

Memorial Sloan Kettering Cancer Center

Adult Medication

This information from Lexicomp^® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

Brand Names: US

Abreva [OTC]

What is this drug used for?

• It is used to treat cold sores.

What do I need to tell my doctor BEFORE I take this drug?

• If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This drug may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

• Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
• Talk with your doctor before you use other drugs or products on your skin.
• This drug may cause harm if swallowed. If this drug is swallowed, call a doctor or poison control center right away.
• Do not give this drug to a child younger than 12 years old without first checking with the doctor.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Severe irritation where this drug was used.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to your national health agency.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Do not take this drug by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
• Use at the first sign of a cold sore.
• Wash your hands before and after use.
• Put on affected part and rub gently.
• Makeup may be used after the skin has dried.
• Do not rub the cold sore. Rubbing the cold sore may make it worse. It may also cause the cold sore to spread to other areas around the mouth.

What do I do if I miss a dose?

• Put on a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not put on 2 doses at the same time or extra doses.

How do I store and/or throw out this drug?

• Store at room temperature. Do not freeze.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

General drug facts

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else’s drugs.
• Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www. wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last Reviewed Date

2020-08-12

Copyright

© 2023 UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.

Last Updated

Monday, December 12, 2022

docosanol topical

What is the most important information I should know about docosanol topical?

Cold sores are contagious before, during and after an outbreak or when blisters are present. Cold sore sufferers should avoid close physical or intimate contact, such as kissing, when having an outbreak.

Do not share docosanol topical with anyone. Sharing may spread the infection.

Avoid getting this medication in the eyes or mouth.

What is docosanol topical?

Docosanol is an antiviral medication used to treat cold sore infections caused by the herpes simplex virus. Docosanol shortens the healing time and the length of time symptoms are present.

Docosanol topical is used to treat cold sores on the face and lips.

Docosanol may also be used for purposes other than those listed in this medication guide.

Who should not use docosanol topical?

Before using docosanol topical, tell your doctor if you have any other medical conditions or if you use any other medications.

The FDA has not evaluated the effects of docosanol topical used during pregnancy. Do not use docosanol topical without first talking to your doctor if you are pregnant.

It is not known whether docosanol topical passes into breast milk. Do not use docosanol topical without first talking to your doctor if you are breast feeding a baby.

Docosanol topical is not approved for use by children younger than 12 years old.

How should I apply docosanol topical?

Use docosanol exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before and after applying docosanol topical.

Docosanol topical should be applied at the very first sign of a cold sore, such as the tingle, redness, bump, or itch.

Docosanol topical is a smooth, white cream that dries clear. It won’t sting or burn and it has no medicinal smell or taste.

Remove any cosmetics before applying docosanol topical. Apply enough docosanol topical to completely cover the cold sore or fever blister and rub in gently and completely.

Docosanol topical is usually applied five times a day until healed. Stop using docosanol topical and see your doctor if the cold sore gets worse or the cold sore is not healed with in 10 days.

If at any time the medication is accidentally removed, re-apply it as soon as possible.

Cosmetics, such as lipstick, may be applied over docosanol topical. However, use a separate applicator, such as cotton swab, to apply cosmetics over an unhealed cold sore to avoid spreading the infection.

Do not share docosanol topical with anyone. Sharing may spread the infection.

Avoid getting this medication in the eyes or mouth.

Store docosanol topical at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Apply the missed dose as soon as you remember, then re-apply the next dose on schedule. It does not matter if the time interval between those doses is reduced.

What happens if I overdose?

An overdose of this medication is not likely to occur. If you suspect an overdose or ingestion of docosanol topical, call an emergency room or poison control center for advice.

What should I avoid while using docosanol topical?

Cold sores are contagious before, during and after an outbreak or when blisters are present. Cold sore sufferers should avoid close physical or intimate contact, such as kissing, when having an outbreak.

Cosmetics, such as lipstick, may be applied over docosanol topical. However, use a separate applicator, such as cotton swab, to apply cosmetics over an unhealed cold sore to avoid spreading the infection.

Do not share docosanol topical with anyone. Sharing may spread infection.

What are the possible side effects of docosanol topical?

No serious side effects are expected with docosanol topical treatment. If you suspect an allergic reaction (difficulty breathing; rash; hives; itching; swelling of your lips, tongue, or face) seek emergency medical attention.

Other less serious side effects are also uncommon. Headache has been reported.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect docosanol topical?

It is not known whether docosanol topical will interact with other medications. Tell your doctor and pharmacist about all other medicines you are using, especially other topical preparations, and talk to your doctor and pharmacist before using any prescription or over-the-counter medicines during treatment with docosanol topical.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2018 Cerner Multum, Inc. Version: 1.07. Revision date: 12/3/2013.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.

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Abreva (docosanol cream) side effects, warnings, directions for use

Abreva

• Generic Name: Docosanol Cream
• Brand Name: Abreva

• Overview
• Professional Information
• Related Resources

Side Effects Center Abreva

Medical Editor: John P. Cunha, DO, FACOEP

Abreva (docosanol cream) is a herpes simplex/herpes treatment used to treat cold sores/fever blisters on the face or lips. This reduces healing time and the duration of symptoms such as tingling, pain, burning and/or itching. Abreva is available both generic and over-the-counter (OTC). Side effects of Abreva are rare and may include:

• itchy skin,
• rash, and
• redness at the injection site

Apply enough Abreva cream to completely hide a cold. sick and follow the instructions on the package. Rub gently but completely. Use 5 times a day until cold sores/blisters heal. Abreva may interact with other drugs. Tell your doctor about all medications and supplements you are taking. Tell your doctor if you are pregnant or planning to become pregnant before using Abreva. Consult your doctor before breastfeeding.

Our Abreva Side Effects Center (docosanol cream) provides a comprehensive overview of available drug information and potential side effects when taking this medication.

This is not a complete list of side effects and they may occur. Ask your doctor about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Abreva Consumer Information

Get emergency medical help if you have signs of an allergic reaction : urticaria; feeling of dizziness; wheezing, difficulty breathing; swelling of the face, lips, tongue, or throat.

Less serious side effects may be more likely, and you may not have them at all.

This is not a complete list of side effects and they may occur. Ask your doctor about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Abreva (Docosanol Cream)

Learn More ‘ Abreva Professional Information

SIDE EFFECTS

No information provided.

Read all FDA Prescribing Information for Abreva (Docosanol Cream)

Read More’ Related Resources for Abreva

Concomitant Drugs

• Denavir
• Famvir
• Valcyte
• Valtrex

• Zovirax
• Zovirax cream
• Zovirax Injection
• Zovirax Ointment

Abreva Patient Information is provided by Cerner Multum, Inc. and Abreva Consumer Information is provided by First Databank, Inc., used under license and subject to their respective copyrights.

Abreva (Docosanol Cream) Side Effects, Images, Usage, Dosage, Overdose at RxList

Abreva

• Generic Name: Docosanol Cream
• Brand Name: Abreva

• Images and Side Effects
• How to Take
• Avoid Taking

Abreva including side effects

Brand names: Abreva, Abreva Pump

Generic name: topical docosanol

• What is topical for docosanol (Abreva, Abreva Pump)?
• What are the possible side effects of topical docosanol (Abreva, Abreva Pump)?
• What is the most important information I should know about topical docosanol (Abreva, Abreva Pump)?
• What should I discuss with my doctor before using docosanol (Abreva, Abreva Pump)?
• How should I use topical docosanol (Abreva, Abreva Pump)?
• What happens if I miss a dose (Abreva, Abreva Pump)?
• What happens if I overdose (Abreva, Abreva Pump)?
• What should I avoid while using topical docosanol (Abreva, Abreva Pump)?
• What other drugs will affect topical docosanol (Abreva, Abreva Pump)?
• Where can I get more information (Abreva, Abreva Pump)?

What is relevant for docosanol (Abreva, Abreva Pump)?

Docosanol topical (skin) is used to treat cold sores on the face and lips.

Docosanol may also be used for purposes not listed in this medication guide.

What are the possible side effects of topical docosanol (Abreva, Abreva Pump)?

Get emergency medical help if you have signs of an allergic reaction : hives; feeling of dizziness; wheezing, difficulty breathing; swelling of the face, lips, tongue, or throat.

Less serious side effects may be more likely, and you may not have them at all.

This is not a complete list of side effects and they may occur. Ask your doctor about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

What is the most important information I should know about topical docosanol (Abreva, Abreva Pump)?

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Follow all directions on the medicine label and container. Tell each of your health care providers about all your illnesses, allergies, and any medications you take.

Information for Abreva patients, including how I should take

What should I discuss with my doctor before using docosanol (Abreva, Abreva Pump)?

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You should not use docosanol topical if you are allergic to it.

Talk to your doctor before using this medicine if you are pregnant or breastfeeding.

Do not use this medicine on children under 12 years of age without consulting a doctor.

How should I use docosanol topical (Abreva, Abreva Pump)?

Use exactly as directed on the label or as directed by your healthcare professional.

Do not take orally. The topical medicine is for use on the skin only. If medicine gets into eyes or mouth, rinse with water.

Use this medicine at the first sign of cold sores, such as tingling, redness, itching, or a blister.

Wash hands before and after applying docosanol.

Remove all cosmetics before using docosanol. Apply enough medication to completely cover the cold sore. Rub gently and completely.

Call your doctor if your symptoms do not improve within 10 days or if they get worse.

Store at room temperature away from moisture and heat. Do not freeze.

Abreva patient information, including the missed dose

What happens if I miss a dose (Abreva, Abreva Pump)?

Give the medicine as soon as possible, but skip the missed dose if it is almost time for the next dose. Do not administer two doses at a time.

What happens if I overdose (Abreva, Abreva Pump)?

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Docosanol overdose is not expected to be dangerous. Seek emergency medical attention or call the Poison Helpline at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

What should I avoid while using topical docosanol (Abreva, Abreva Pump)?

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Do not give this medicine to another person.