Alcohol and tylenol pm: Tylenol PM and Alcohol/Food Interactions
Tylenol PM and Alcohol/Food Interactions
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There are 2 alcohol/food/lifestyle interactions with Tylenol PM (acetaminophen / diphenhydramine).
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Ask your doctor before using diphenhydrAMINE together with ethanol.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Tylenol PM drug interactions
There are 500 drug interactions with Tylenol PM (acetaminophen / diphenhydramine).
Tylenol PM disease interactions
There are 11 disease interactions with Tylenol PM (acetaminophen / diphenhydramine) which include:
- alcoholism
- liver disease
- depression
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
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More about Tylenol PM (acetaminophen / diphenhydramine)
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Drug Interaction Classification
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
|---|---|
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
| Unknown | No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Is It Safe To Mix Alcohol & Tylenol (Acetaminophen)?
Mixing Tylenol (acetaminophen) and alcohol can be dangerous and can damage your liver and kidneys. Learn how the two substances interact and how it can be harmful to your body.
Article at a Glance:
It can be harmful to mix alcohol and Tylenol.
The biggest risk tends to be to the liver, but this combination can also increase the risk of kidney disease.
You should never drink more than three alcoholic beverages in a day, and you should always make sure you’re not combining Tylenol with any other medicine that contains acetaminophen.
You should never take more than 3,000 mg of acetaminophen in a day, and you shouldn’t take it for longer than ten days in a row.
Can You Mix Alcohol and Tylenol?
To put it simply, if you’re asking “can you mix alcohol and Tylenol,” the answer is no.
The standard guideline is that if you’re taking acetaminophen, you should have no more than three drinks in a day, but many physicians and pharmacists will recommend avoiding alcohol altogether. This is because the risks are so high.
For example, a standard serving size of alcohol tends to be much smaller than what most people would think. With wine as an example, a standard drink is only five ounces. It’s very easy to go over what’s meant as the guideline for moderate drinking and put yourself at risk as a result.
The Risks of Mixing Alcohol and Tylenol
There are enzymes found in your liver that are responsible for breaking down substances that enter the body. If you drink, it can make it more difficult for your liver to break down and process the Tylenol. When this happens, you’re at risk for severe liver damage. This risk goes up as you take more of the pain reliever or drink more alcohol.
When your body uses acetaminophen for fever or pain relief, it produces a toxic substance called NAPQI. NAPQI is metabolized by a substance called glutathione. By taking too much acetaminophen, the body’s glutathione is depleted, so it is unable to metabolize and process other harmful substances. This leads to a toxic buildup of NAPQI. When toxic substances build in the body, it can lead to liver damage.
When you experience liver damage, it can reduce the functionality of this vital organ and it can also lead to pressure in the brain, and abnormal bleeding or swelling.
What is Tylenol?
Tylenol is the brand name for acetaminophen, an over-the-counter (OTC) pain and fever reducer.
It’s one of the most commonly used pain medicines in the world and can be used to treat everything from headaches to arthritis. Acetaminophen is also an ingredient in other combination products available as prescriptions and over-the-counter.
There are many different forms of Tylenol on the market including Tylenol Children’s, Tylenol Extra Strength, Tylenol Cold and Flu, Tylenol Allergy, Tylenol PM, and others.
Some of the brand name medications that contain acetaminophen include Theraflu and DayQuil, which are used to treat colds and the flu. Prescription drugs with acetaminophen include Norco and Percocet, among others. When acetaminophen is included in prescription pain relievers, it’s combined with another active ingredient, often opioid painkillers.
How Does Acetaminophen Work? Is it Safe?
Acetaminophen is classified as a non-opioid analgesic. It blocks an enzyme that produces prostaglandins, which create pain and inflammation. It’s different from NSAIDs, like aspirin, because it doesn’t reduce swelling and inflammation.
It can also be used for the treatment of migraines, and it’s often combined with aspirin and caffeine in the drug Excedrine.
Despite how widely used Tylenol is, and the fact that it’s considered relatively safe, there is the potential for an acetaminophen overdose. People who take more than the maximum dosage of Tylenol, which is usually 3,000 milligrams in a day, may experience severe side effects including liver damage, acute liver failure, or death. The dose should never exceed 3,000 mg per day unless advised by a physician.
For the most part, acetaminophen overdoses are accidental. People simply don’t realize how much they’re taking and how severe the side effects can be.
Symptoms of liver damage can include yellowing of your skin or the whites of your eyes, pain in the upper right portion of your abdomen, swelling of the abdomen, loss of appetite, nausea, vomiting, tiredness, and sweating.
Liver damage from the combination of alcohol and Tylenol is called acute liver damage, and this condition can occur very quickly.
For many people, it’s possible to recover from liver damage resulting from mixing alcohol and Tylenol, but for some people, the damage can be pervasive or can lead to death.
Some people are at a higher risk of liver damage than others. For example, people with existing liver damage should not use or combine the two substances. Also, binge drinkers or heavy drinkers should avoid Tylenol.
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Editor – Nicole LaNeve
Nicole leads a team of passionate, experienced writers, editors and other contributors to create and share accurate, trustworthy information about drug and alcohol addiction, treatment and recovery for The Recovery Village and all Advanced Recovery Systems sites.
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Medically Reviewed By – Dr. Conor Sheehy, PharmD, BCPS, CACP
Dr. Sheehy completed his BS in Molecular Biology at the University of Idaho and went on to complete his Doctor of Pharmacy (PharmD) at the University of Washington in Seattle. Read more
American Society of Health-System Pharmacists. “
Medical Disclaimer
The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.
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Tylenol™ – instructions for use, doses, side effects, reviews of the drug:
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Analogs
All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics
Product Description Tylenol™ Caplets (caplets), 500 mg) based on the label, approved by the manufacturer in 2000
Approval date: 07/31/2000
Content
- Active substance
- ATX
- Pharmacological group
- Nosological classification (ICD-10)
- Composition and form of release
- pharmachologic effect
- pharmachologic effect
- Indications
- Contraindications
- Use during pregnancy and lactation
- Dosage and administration
- Side effects
- Precautionary measures
- Storage conditions
- Best before date
- Reviews
Active ingredient
Paracetamol* (Paracetamol*)
ATX
N02BE01 Paracetamol
Pharmacological group
Anilides
Nosological classification (ICD-10)
ICD-10 code list
Composition and formulation
1 caplet contains paracetamol 500 mg; in a blister 10 pcs.
, in a box 1 blister or in strips of 2 pcs., in a box 50 strips.
Pharmacological action
Pharmacological action –
analgesic , antipyretic .
Inhibits cyclooxygenase, inhibits the synthesis of PG in the central nervous system and their stimulating effect on the thermoregulatory center of the hypothalamus; increases heat transfer.
Inhibits cyclooxygenase, inhibits the synthesis of PG in the central nervous system and their stimulating effect on the thermoregulatory center of the hypothalamus; increases heat transfer.
Indications
Pain of mild to moderate intensity (including headache, toothache, sore throat and general malaise), fever.
Contraindications
Hypersensitivity, severe impairment of liver and kidney function, deficiency of glucose−6-phosphate dehydrogenase, children’s age (up to 12 years).
Use during pregnancy and lactation
Acceptable, but only on medical prescription.
Dosage and Administration
Information for healthcare professionals only.
Are you a healthcare professional?
Inside, 2 caplets 3-4 times a day, but not more than 8 caplets per day.
Side effects
In rare cases, nausea, abdominal pain, allergic reactions (skin rash, itching, urticaria).
Precautions
Do not use more than 10 days for pain and 3 days as an antipyretic. It should not be taken together with other drugs containing paracetamol.
Storage conditions
At a temperature of 15–30 °C.
Keep out of reach of children.
Expiry date
4 years.
Do not use after the expiry date which is stated on the pack.
Update date: 11/21/2018
Reviews
Read all reviews and leave your own.
Information for healthcare professionals only.
Are you a healthcare professional?
Tylenol PM | 59 factors
66 points
Tylenol PM
Tylenol PM
Why is Tylenol PM better than others?
- Paracetamol?
500mg vs 175.
77mg - Tablets per pack?
100 vs 44.37 - Dosage period?
14 vs 7.75 - Shelf life?
36months vs 31.6months - Diphenhydramine?
25mg vs 0.48mg
77mg Tylenol PM
vs
Tylenol Extra Strength
Tylenol PM
vs
Tylenol Regular Strength
Tylenol PM
vs
Tylenol Arthritis Pain
Tylenol PM
vs
Tempra Infant Drops
Tylenol PM
vs
Panadol Night
Tylenol PM
vs
Excedrin PM
Tylenol PM
vs
Aleve GelCaps
Tylenol PM
90 002 vs
Tylenol Sinus Congestion & Pain Severe
Tylenol PM
vs
Motrin PM
Tylenol PM
vs
Advil
9001 9 Composition
ibuprofen
Ibuprofen is a non-steroidal anti-inflammatory drug. The analgesic effect of ibuprofen takes effect immediately, however, the anti-inflammatory effects can last up to a week.
paracetamol
Paracetamol (acetaminophen in the US) is classified as a mild analgesic. It suppresses the feeling of pain, but does not treat the cause.
aspirin
Aspirin can be used as an analgesic, antipyretic and anti-inflammatory agent.
caffeine
Studies have shown that caffeine can increase the effectiveness of many analgesics, resulting in better, faster pain relief.
codeine
Codeine is an opiate used to treat mild to moderate pain. Opioids can change mood, sometimes resulting in a feeling of euphoria. It may be helpful in relieving pain, but addiction and withdrawal symptoms may occur.
Has more than one active ingredient
✔Tylenol PM
Product contains more than one active ingredient. These combinations usually complement each other, and sometimes one ingredient can enhance the effectiveness of another.
naproxin
Naproxen is an anti-inflammatory that can be used to treat a variety of pain symptoms.
Effects
Toothache
✔Tylenol PM
Toothache is pain in and around the teeth and jaw, often caused by caries.
Anti-Inflammatory
✖Tylenol PM
Anti-inflammatory drugs are especially good for muscle and joint pain as they not only block the pain, but also treat the cause.
Antipyretic (reduces body temperature)
✔Tylenol PM
Antipyretic drugs help to reduce body temperature. This helps patients feel better, however, this is not always recommended as fever may be a natural defense against infections.
Rheumatic pain
✖Tylenol PM
Rheumatic pain is pain in the joints and connective tissue, most commonly caused by arthritis.
Muscle pain
✔Tylenol PM
Muscle pain can be caused by exercise or other stress, and infections such as the flu.
Migraine
✔ Tylenol PM
Migraine is a very severe headache often accompanied by other symptoms such as flickering light, blind spots, tingling and sensitivity to light.