Alcoholic bleeding nose: The request could not be satisfied

14.05.198007.12.2021 by alexxlab

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Death of man hospitalised after nose bleed linked to alcohol abuse

Tom O’Connor, aged 63, with an address at 1 Parkowen, off Quaker Road, Cork, died in the Mercy University Hospital from multi-organ failure 18 days after he was admitted to hospital with a nose bleed.

But that minor complaint was the first sign that his liver wasn’t working properly, Cork Coroner’s Court heard.

Mr O’Connor, a single man who had been drinking since he was 14, was admitted to the South Infirmary on January 2 with a nose bleed. He was subsequently transferred to the Mercy University Hospital where he died on January 20.

His rapid deterioration and death required that a post mortem be carried out. Assistant State Pathologist Dr Margaret Bolster carried out the examination at Cork University Hospital and found that Mr O’Connor had extensive cirrhosis of the liver. He also had pneumonia and heart disease.

She recorded the cause of death as total organ failure related to alcohol related end-state cirrhosis.

City coroner Myra Cullinane said the nose bleed Mr O’Connor suffered on January 2 would have been the first sign that his liver was beginning to malfunction.

The badly damaged liver would have affected his body’s ability to clot blood, she said, resulting in the nose bleed.

The damage to the liver would also have had a knock-on effect on Mr O’Connor’s other organs, which then began to shut down, the inquest heard.

Having looked at all the evidence, Ms Cullinane said the only verdict open to her was to record a verdict of death by misadventure — the unintended outcome of an intended action.

She expressed her sympathy to members of the O’Connor family.

In a separate inquest, the court heard evidence surrounding the death of Joseph Geary, aged 48, whose body was recovered from the River Lee, near Kennedy Quay, on the morning of June 3, 2005.

A post mortem found that Mr Geary, with an address at 28, Lower Cork Street, Mitchelstown, Co Cork, but who had been living on and off at St Vincent’s Hostel in the city since 2001, had 289 milligrammes per centilitre of alcohol in his blood.

There were traces of two anti-depressant drugs in his system but they were within the therapeutic range, the inquest heard.

“I have no evidence he entered the river on purpose,” Ms Cullinane said.

It appears most likely that Mr Geary fell into the river from the unprotected quay, she said.

She recorded a verdict of death by misadventure.

What Is Alcoholic Nose? (Rhinophyma)

Alcohol nose, or drinkers nose, is a skin condition commonly characterized by a bumpy, red or swollen appearance of the nose and cheeks. For years, it was widely believed that this condition was caused by alcohol use disorder or alcoholism. However, new research released in 2015 proved otherwise.

According to the report, rhinophyma (the medical name for alcoholic nose) actually has nothing to do with how much or how little a person drinks. With very little connection between rhinophyma and alcoholism, how did the myth of alcoholic nose start and why is it still perpetuated today?

What Is Alcoholic Nose?

Alcoholic nose is a skin condition commonly characterized by a swollen, red and bumpy appearance on the nose. While this look is frequently referred to as alcoholic nose or drinkers nose, it’s actually a skin disorder called rhinophyma.

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Rhinophyma is a subtype of another skin condition called rosacea, which causes chronic inflammation of the skin. The chronic inflammation causes broken blood vessels and pustules on or around the nose, giving it the red, swollen and bumpy look often associated with alcoholic nose.

Of the four subtypes of rosacea, rhinophyma is thought to be one of the worst. It forms gradually over the years and is typically the result of not treating a less severe form of rosacea early on.

While women are diagnosed with rhinophyma, the condition is much more common in men. People with fair skin or those with a family history of rosacea are at a higher risk of suffering from the alcoholic nose.

Can Alcoholism Cause Rhinophyma?

It was previously thought that excessive alcohol consumption was the cause of rhinophyma – hence the nickname alcoholic nose or drinkers nose. Alcohol abuse can cause vessels to enlarge in the face and neck creating redness or flushed skin. Due to this, the idea that alcoholism could cause rhinophyma held up for many years.

However, a study published by the University of South Florida Morsani College of Medicine in 2015 disproved this theory. Many of the patients that participated in this study were clinically diagnosed with rhinophyma but did not suffer from alcoholism or even drink regularly.

While this study disproved the theory that alcohol abuse causes drinkers nose, researchers were not able to uncover what did cause rhinophyma in their patients. However, there is evidence to suggest that ethnic and genetic predisposition may cause this disfiguring skin condition as it runs in families of English, Scottish, Scandinavian or Eastern European descent. Despite these facts, the known cause of rhinophyma remains a mystery today.

How Alcohol Affects Rosacea

Although alcohol abuse does not cause rhinophyma or rosacea, it can aggravate the condition. As many as two out of three patients with rosacea experience flare-ups when they consume alcohol.

Alcohol aggravates symptoms of rosacea because drinking enlarges the body’s blood vessels. When the blood vessels are more open, they allow more blood to flow to the surface of the skin, creating a flushed look that is typically referred to as the ‘alcohol flush.’ The redness can spread anywhere on the body but is most noticeable on the face, shoulders, and chest. For those already suffering from redness due to rosacea, alcohol can make this symptom increasingly worse.

According to a survey of patients suffering from this skin condition, red wine is more likely to trigger flare-ups or worsen rosacea than other drinks. Doctors theorize it’s because of an additional chemical in red wine that also works to enlarge blood vessels, letting far more blood than usual flow to the surface of the skin.

In order to manage these symptoms of rosacea, doctors suggest that patients with this condition:

Avoid red wine
Don’t cook with alcohol
Have a tall glass of water in between every alcoholic drink
Drink in extreme moderation
Dilute alcohol drinks with seltzer water
Stop drinking alcohol

Since everyone has different levels of sensitivity to alcohol, those suffering from rosacea will have to test and build their own boundaries to avoid severe flare-ups of alcoholic nose. A recent survey of rosacea patients found that 90 percent of responders found that limiting their alcohol consumption helps greatly to reduce sudden outbreaks.

The Stigma Of Addiction And Alcoholic Nose

Although alcoholic nose has nothing to do with drinking, the general public still widely associates this condition with alcohol abuse. Due to this close association, those that suffer from rhinophyma often feel self-conscious not just because of their appearance, but because others might assume that they’re an alcoholic. This assumption brings up a much larger issue surrounding the addiction community – the stigma surrounding those suffering from this heartbreaking disease.

People who have rhinophyma are so scared of being labeled as an alcoholic that some report avoiding social activities or going out on a regular basis. In doing so, the stigma of addiction continues to thrive. This stigma results in prejudice, avoidance, rejection, and discrimination against people who have an addiction because others are unwilling to show compassion to those different from them. Unfortunately, the shame of addiction often prevents those with alcoholism from reaching out for help.

The reality is, there are more than 15 million Americans suffering from an alcohol use disorder according to the National Institute on Alcohol Abuse and Alcoholism. Of this population, less than eight percent will receive detox treatment for alcoholism. To get more people suffering from alcoholism the help they desperately need, the stigma surrounding addiction must be broken.

People can start deconstructing the stigma of addiction by:

Learning about the disease
Talking about addiction with others
Breaking down misconceptions about addiction
Recognizing fact-based warning signs of alcohol abuse
Speaking up when someone is mistreated because of their addiction
Offering compassionate support to those struggling
Avoiding hurtful labels like “addict” and “drunk”

The misconception that rhinophyma equals alcoholism is an outdated stereotype that can breed negative self-esteem and social anxiety. It can also prevent those actually suffering from alcoholism from getting the help they need.

—

Despite being widely considered a symptom of alcoholism, rhinophyma had nothing to do with alcohol consumption. This misguided and popular thought process perpetuates the stigma of addiction and prevents those suffering from alcoholism from seeking help.

Alcoholic Nose (Rhinophyma): Can Alcohol Affect the Appearance of the Nose?

Classic Hollywood cartoons and comedy bits often call upon the jolly alcoholic character to lighten the mood or provide comic relief. In an attempt to make light of a serious condition, this character may interrupt scenes with bumbling, slurring bouts of playful drunken behavior.

Classic comedians such as W.C. Fields have made entire careers playing this type of character. All of these characters also share a similar look: chubby cheeks, and a red, bulbous nose.

“Alcoholic nose,” or drinker’s nose, is a skin condition commonly identified by a red, bumpy, or swollen appearance of the nose and cheeks. It’s hard to say when exactly this condition became linked with heavy alcohol use, but stereotypes in popular media have kept this connection alive.

While alcohol can stay in your system and cause damage, there is thought to be very little connection between alcohol use and this skin condition.

So what exactly is “alcoholic nose,” and what actually causes it?

Alcoholic Nose, Nose Redness, and Rhinophyma

What is commonly called “alcoholic nose” is actually a skin condition called rhinophyma (Greek for “nose growth”). Rhinophyma is in a category of skin conditions known as rosacea, which causes chronic inflammation of the skin. This chronic inflammation is caused by broken blood vessels and sores on or around the nose, causing it to appear red, swollen, and bumpy.

When blood vessels burst, it makes the blood visible under the surface of the skin, leading to skin redness. In more severe cases, the nose and cheeks can take on a purple hue and start to become severely disfigured as they become more bulbous.

There are four subsets of rosacea, and rhinophyma is thought to be the most severe of them all. It’s a progressive condition that forms gradually over years and is thought to be the result of an untreated, less severe form of rosacea.

However, only a small percentage of people with rosacea will develop the condition. One study found that out of 108 patients with rosacea, only 15 were noted to also have rhinophyma, almost all of whom were men.

While women can be diagnosed with the condition, it is found much more commonly in men. People with fair or light skin tone, or those with a family history of rosacea, are more likely to develop rhinophyma.

The Stigma of Rhinophyma or Alcoholic Nose

Someone suffering from rhinophyma may also face stigma (shame) associated with the disorder. As with many health conditions, stigma can be a barrier to that person seeking treatment to help with their condition. Because of the very visible nature of rhinophyma, a person with the condition might feel incredibly self-conscious about their nose. They may feel hesitant about meeting new people or even going to the grocery store for fear of being made fun of or judged.

In the past, and even in modern times, rhinophyma was largely considered to be a side-effect of alcoholism or alcohol use disorder. Someone who has a bulbous, swollen red nose may suffer from incorrect judgments and assumptions about their character and substance use habits.

The truth is that studies have shown there is very little, if any, connection between alcohol use and rhinophyma. The condition is understood and treated as a condition that is totally separate from alcohol use disorder.

Does Alcoholism Cause Advanced Rosacea of the Nose?

Redness of the skin is closely associated with alcohol use, so it makes sense that rhinophyma came to be linked with alcohol use disorder. It is true that drinking alcohol can cause the cheeks and face of some people to become red or flushed. There are a couple of reasons why some people may experience skin redness when consuming alcohol.

Cleveland Clinic explored this topic and concluded that facial redness can occur for two reasons: an enzyme deficiency or rosacea. Both of these reasons are closely related to genetics and ethnic background.

Enzyme deficiency: Cleveland Clinic skin doctor Alok Vij explains that “many Asian populations have a deficiency in alcohol dehydrogenase, the enzyme that breaks alcohol down.” As alcohol enters blood vessels’ cells, the cells dilate, making your face flushed or red. This can also make you feel warm. If you have less of this particular enzyme, it will be easier for your face to get flushed when you drink alcohol. Because many Asians are affected by this, the condition is sometimes casually referred to as “Asian flush.”
Rosacea: Cleveland Clinic identifies fair-skinned people with Northern European ethnic backgrounds as persons who may have some degree of flush while drinking due to rosacea. Rosacea can be easily triggered by particular foods and diets. For example, things like chocolate, alcohol, hot drinks, and spicy foods can cause a person’s rosacea to flare up.

While some people may experience flushing or redness when they consume alcohol, this doesn’t mean those people all suffer from rhinophyma. Wrong assumptions based on similar traits, such as flushed skin after drinking, have led to misinformation about the true causes of the condition.

That being said, there may be some slight truth to the idea that drinking alcohol can contribute to the development of rhinophyma. Because drinking alcohol has been found to make rosacea worse in some people, it may also contribute to worsening the symptoms of rhinophyma.

What Is Rosacea?

As discussed above, rosacea can be a main contributing factor to redness and flushing of the cheeks. To understand how rosacea can lead to rhinophyma, it’s important to understand what rosacea is, its symptoms, and how it develops.

The Mayo Clinic explains that rosacea is a common skin condition that causes redness and visible blood vessels on the face. It may also produce small, red, pus-filled bumps. These signs and symptoms may flare up for weeks to months and then go away for a while.

Rosacea can often appear on the outside to be an acne outbreak or natural coloring on the cheeks. The condition tends to affect fair-skinned, middle-aged women more often, but anyone of any age or skin tone can develop the condition. There are currently no cures for rosacea, but there are options available to treat specific symptoms.

The symptoms of rosacea include:

Facial redness: When blood vessels in the face become visible under the surface of the skin, it causes a general redness or flushed appearance on the face. In general, this redness is limited to the center of the face on the nose and surrounding areas.
Swollen, red bumps (can be pus-filled): These swollen, red bumps can easily be mistaken for an acne outbreak. Much like acne, these bumps may become filled with pus. The bumps and surrounding skin may be hot, tender to the touch, and uncomfortable.
Eye issues: Swelling of the face is a common symptom of rosacea. People with the condition may frequently have dry, irritated, or swollen eyelids. Rosacea that occurs strictly around the eyes is commonly referred to as “ocular rosacea.”
Swollen, bulbous nose: If left unchecked, rosacea can progress to the point where it thickens the skin on the nose, leading to a bulbous, swollen appearance. This thickening of the skin is called rhinophyma and is the result of advanced rosacea.

Alcohol and Other Triggers for Rosacea of the Nose

A flare-up of rosacea symptoms can be triggered by the consumption of many different foods and drinks, including alcohol. Rosacea can even be triggered by environmental factors.

Some potential rosacea flare-up triggers include:

Alcohol
Spicy foods
Hot drinks
Stress (and other strong emotions)
Sunlight
Wind
Extreme temperatures (both hot and cold)
Drugs that dilate blood vessels
Certain cosmetic and skincare products
Physical activity

While it’s true that alcohol use may trigger rosacea flare-ups, this does not mean that every person with rosacea will automatically develop rhinophyma. It is an extreme side effect only experienced by a small percentage of people who suffer from rosacea. That being said, someone who already has rhinophyma may find their condition is worsened by drinking alcohol.

The Truth of Alcohol’s Effect on Rhinophyma

It’s mostly false to say rhinophyma is caused by alcohol use disorder. There are many people who develop the disorder but do not drink alcohol, or drink very minimal amounts. In some cases, the stigma associated with rhinophyma can prevent people from seeking treatment for fear of being labeled an alcoholic.

The National Institutes of Health (NIH) explains the truth in the following section from its page on the condition:

“Historically, rhinophyma was erroneously considered to be linked with alcohol consumption because substances such as alcohol and caffeine can cause local vasodilation, which worsens the symptoms. This alleged association with alcohol has caused much social stigma and loss of self-esteem in patients suffering from the disease, with several nicknames for the condition such as ‘whiskey nose’ and ‘rum nose. ’ ”

Treatments for ‘Alcoholic Nose’

There are two options to treat rhinophyma: medication and surgery.

Medication: While there are no medications that can fully reverse the effects of alcoholic nose (rhinophyma), some of the symptoms can be managed. Generally speaking, once rhinophyma develops, it can be very difficult to manage with medication alone. Nose redness as a side effect of rosacea can be managed with prescription medication with some degree of success.

Some medications used to treat rhinophyma include:

Topical and oral antibiotics to reduce inflammation and redness, such as metronidazole, sulfacetamide, tetracycline, erythromycin (Erythrocin Stearate), and minocycline (Minocin)
Topical medications that help minimize inflammation, such as tretinoin (Retin-A) and azelaic acid (Azelex)
Oral capsules that prevent skin glands from producing oil, such as oral isotretinoin

Surgery: Surgery is the most common treatment for advanced rhinophyma. Enlarged blood vessels and tissue overgrowth are what cause the misshaping of the nose. This can be permanent if the affected area isn’t removed. Surgery is considered the most effective option for long-term success.

The following surgical treatments and methods are commonly used to treat the condition:

Surgery using a scalpel
Laser resurfacing with a carbon dioxide laser
Cryosurgery, which uses extremely cold temperatures to freeze and remove unwanted tissues
Dermabrasion, which uses a small, rotating tool to remove the top layers of skin

The longer tissue overgrowth remains on the skin, the more likely it is to become permanent. If you are suffering from rhinophyma, talk to your doctor or dermatologist to develop a plan for treatment.

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You’re stronger than you may think, and we’re here to help. Call us today at 800-543-9905 for a no-cost consultation from one of our mental health professionals.

FAQs:

Why does alcohol cause red nose?

Alcohol use can worsen a red nose, also known as rhinophyma, but doesn’t cause it to occur. Some people become red-faced or flushed when they drink alcohol, and this is determined by ethnic background and genetics.

Can rhinophyma be reversed?

While there are no treatments that can completely reverse rhinophyma, medications and surgery can lessen the condition if caught in time. The longer rhinophyma goes without treatment, the more likely the condition will become permanent.

Alcohol Nose Bleeds: Causes, Treatment & Prevention

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Case studies suggest that there is a significant association between nosebleeds and alcohol because of growing evidence of alcohol nose bleeds.

High alcohol consumption can be a triggering factor of nose bleeding as alcohol influences the metabolic process of the body, resulting in abnormal regulation of the blood vessels. Consequently, alcohol nose bleeds occur frequently to people who drink excess alcohol. Even though nosebleeds can be frightening, most nosebleeds are not dangerous. There are two types of nosebleeds, depending on the location. Anterior nosebleed comes from the front of the nose and is the most common kind of nosebleed. It occurs due to the breaking of capillaries inside the nose. Nose bleeding that occurs from the deepest part of the nose is known as posterior nosebleed. It occurs in people who have high blood pressure and who have sustained nose injuries.

Causes

Common causes of nosebleed include dry environmental conditions and nose injury. Additionally, dry nose, nose picking, excessive nose blowing, side effects of certain medications like aspirin, hypertension, inhalation of chemical irritants, and prolonged use of nasal spray are some of the risk factors that cause nose bleeds.

Alcohol and drug use are the most important causes of nosebleed as alcohol is known to affect the platelet function. In addition, consumption of alcohol is also associated with hypertension and dehydration. Drinking excessive alcohol can cause nosebleeds as alcohol has the tendency to prohibit blood clotting and dilates blood vessels. Dilation of blood vessels reduces the blood’s ability to clot. Excessive consumption of alcohol reduces activity of platelets, the blood cells that are responsible for forming blood clots. This results in thinning the blood and thereby increases the chance for a nosebleed and prolongs bleeding time. High consumption of alcohol also leads to changes in blood pressure, which may be an important cause for alcohol nose bleeds. Alcohol has a number of effects that interfere with hemostasis that will increase bleeding problems. Regular use of three or more drinks of alcohol per day is a risk factor of hypertension. Dehydration is another important cause of nose bleeding as dry nose is one of the main problems that leads to nosebleeds. Regular alcohol consumption causes dehydration that can cause nosebleeds.

Treatment

Quick blood clotting is the first step to stop nosebleed as profuse nose bleeding is a scary situation. Ensure to keep calm and relaxed. Sit comfortably and pinch the soft parts of the nose firmly for 10 minutes so as to stop nose bleeding. You can breathe through your mouth during this time. In order to prevent draining of blood into throat, lean forward. You can also apply ice packs to arrest bleeding. If bleeding continues, medical attention is required.

It is important to prevent re-bleeding. For this, it is essential not to pick or blow your nose. You should also keep your head higher than the level of your heart and you should avoid bending down for several hours. Also, avoid sneezing or coughing, if possible. Strenuous activities such as exercise and weight lifting should also be avoided.

Prevention

Mostly, nosebleeds occur during dry climates. Using a humidifier can help to prevent nosebleeds. Petroleum jelly and saline nasal sprays can help keep the nasal passages moist as a dry nose cause nose bleeding. Picking your nose and blowing vigorously should be avoided. Stop smoking as smoking may lead to a dry nose. Limit alcohol intake to prevent alcohol nose bleeds.

Nosebleeds are not a serious health condition and people can recover without any long term effects. However, if nosebleeds occur frequently, it may be a symptom of underlying health condition and should be addressed immediately.

References:

http://www.nhlbi.nih.gov/health/health-topics/topics/thcp/causes.html
http://www.ncbi.nlm.nih.gov/pubmed/854058?dopt=Abstract&access_num=854058&link_type=MED
http://general-medicine.jwatch.org/cgi/content/full/1994/1007/7

Warning: The reader of this article should exercise all precautionary measures while following instructions on the home remedies from this article. Avoid using any of these products if you are allergic to it. The responsibility lies with the reader and not with the site or the writer.

More articles from the Diseases and Ailments Category

Can Cocaine Cause Nose Bleeds?

Nose bleeds are inconvenient, messy and sometimes painful. Most people will get at least one nose bleed during their life. However, some people get frequent nose bleeds. One risk factor for nose bleeds is cocaine use. If you or someone you know uses cocaine, you may be at increased risk for nose bleeds, especially if you snort the drug. Therefore, it is important to understand how cocaine causes nose bleeds, how to manage them, and what complications can arise.

Article at a Glance:

Important points to remember about cocaine and nose bleeds include:

Snorting cocaine can lead to nosebleeds because of damage to the skin and blood vessels in the nose
Most nose bleeds can be managed at home
Nose bleeds that last for longer than 20 minutes need medical attention
Other nasal symptoms like sniffing and runny nose can also result from snorting cocaine
Over time, cocaine use can damage the bone structure inside the nose

Snorting Cocaine and Nose Bleeds

Snorting cocaine can cause a few different nasal symptoms like:

Nose bleeds
Frequent sniffing and runny nose
Sinus problems
Problems with your sense of smell
Scabs inside the nose

Nose bleeds are a common side effect of snorting cocaine. Doctors think that nose bleeds from cocaine are due to a couple of different factors. Snorting cocaine can both irritate the skin and harm the blood vessels in the nose. Ironically, because cocaine makes blood vessels constrict, in some cases doctors use it to help nose bleeds. For this reason, in a hospital setting, topical cocaine is sometimes used to treat or prevent severe nosebleeds. However, it is important to remember that this type of cocaine is topical — not snorted. Additionally, doctors use medical-grade cocaine and not the kind bought on the street.

How Does Snorting Cocaine Cause Nose Bleeds?

Snorting cocaine can cause problems to the skin and tissues in the nasal septum, the wall in the nose between the nostrils. Over time, snorting cocaine can cause wounds in the nasal septum. Symptoms of these wounds include:

Nose bleeds
Facial pain
Destruction of the skin, tissues and bones in the nose

Snorting cocaine causes the nasal blood vessels to constrict, meaning that they carry less blood. However, the tissues in the nose rely on this blood flow to stay healthy. Without enough blood, the tissue may become unhealthy or die. Therefore, snorting cocaine can damage the skin, bones and tissues in the nose. In severe cases, the entire nose can collapse.

Injecting Cocaine and Nose Bleeds

When a person injects cocaine into their veins, the drug does not come into contact with the nose. So, injecting cocaine does not cause nose bleeds. However, injecting cocaine has been linked to other kinds of bleeding, including brain bleeds.

Smoking Cocaine and Nose Bleeds

Cocaine does not come into direct contact with your nose when you smoke it. Therefore, smoking cocaine is not likely to cause nosebleeds. Snorting cocaine is more commonly associated with nose bleeds.

How to Treat a Nose Bleed from Cocaine Use

About 90% of nose bleeds are minor and can be treated at home. Nose bleeds from cocaine use are similar to nose bleeds caused by other factors and can often be treated the same way. Steps to treat a nosebleed at home include:

Sit down to avoid falling
Lean forward to avoid swallowing blood
Breathe through your mouth
Gently squeeze your nostrils closed with your thumb and index finger for 10 minutes
Do not put anything (like gauze or tissue) inside your nose

If your nose does not stop bleeding after 20 minutes, you should seek medical attention. Most nose bleeds happen in just one nostril. Nose bleeds that happen in both nostrils at the same time can be serious indicators of a health issue and harder to control. In very rare cases, nose bleeds can be serious enough to be life-threatening. Risk factors for severe nose bleeds include:

Having just had surgery on your nose
Being on blood thinners
Having a problem with your natural blood clotting factors
Having an aneurysm in the blood vessels in your nose

Sources
Richards, JR; Laurin, EG; Tabish, N; Lange, RA. “Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol.” The Journal of Emergency Medicine, March 2017. Accessed June 12, 2019.
Yaman, Huseyin; Aydın, Yusuf; Yılmaz, Suleyman; et al. “Recurrent and Massive Life Threatening Epistaxis due to Nasal Heroin Usage.” Clinical and Experimental Otorhinolarynology, September 2011. Accessed June 12, 2019.
Schwartz, RH; Estroff, T; Fairbanks, DN; Hoffmann, NG. “Nasal Symptoms Associated with Cocaine Abuse During Adolescence.” Archives of Otolarynology, January 1989. Accessed June 12, 2019.
Guyuron, B; Afrooz, PN. “Correction of Cocaine-related Nasal Defects.” Plastic and Reconstructive Surgery, March 2008. Accessed June 12, 2019.
U.S. National Library of Medicine. “Nosebleed.” August 25, 2017. Accessed June 12, 2019.
Tabassom, Ayesha; Cho, Julia. “Epistaxis (Nose Bleed).” StatPearls, January 30, 2019. Accessed June 12, 2019.

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Non-alcoholic Steatohepatitis (NASH) | Cedars-Sinai

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Overview

Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD). NAFLD is caused by buildup of fat in the liver. When this buildup causes inflammation and damage, it is known as NASH, which can lead to scarring of the liver. Scarring of the liver is a potentially life-threatening condition called cirrhosis

Symptoms

There are often no outward signs or symptoms associated with NASH. The most common symptoms are:

Fatigue
Pain in the upper right abdomen (usually mild)

NASH may lead to cirrhosis of the liver, causing one or more of the following symptoms as the condition progresses:

Causes and Risk Factors

NASH is most common in patients who are overweight or obese.

Other risk factors include:

Diagnosis

The Cedars-Sinai Fatty Liver Program uses the most advanced diagnostic technology available and continues to investigate new ways to identify the NAFLD and NASH.

Diagnosis generally begins with a physical exam and a review of the patient’s medical history. If NAFLD or NASH are suspected, blood tests will be done to determine how the liver is working. Imaging tools, such as magnetic resonance imaging (MRI), or ultrasound may also be used to help.

If NASH is suspected, the patient will undergo a liver biopsy. During this procedure, a needle is used to remove a small piece of tissue from the liver, which will then be examined under a microscope. This allows the physician to determine if any scarring or inflammation of the liver tissue has occurred. Patients are usually sedated during the liver biopsy.

The Fatty Liver Program also uses special MRI technology, called MR-EFF (elastography fat fraction), to determine the percentage of fat and scarring present. This non-invasive diagnostic tool may eliminate the need for a liver biopsy.

Treatment

The knowledgeable and highly trained experts in the Fatty Liver Program are dedicated to providing each patient with the best possible treatment.

While there is no standard treatment for patients NASH, lifestyle changes have been shown to affect its progression. This may include losing weight, maintaining a healthy diet, or addressing underlying conditions such as hypothyroidism and diabetes.

The Fatty Liver Program takes an integrated approach to treatment, combining nutritional and lifestyle expertise and support with access to the latest clinical trials and research.

It is important for patients with NASH to avoid consuming excessive alcohol as this can contribute to the condition.

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Alcohol-Induced Liver Disease | Cedars-Sinai

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What is alcohol-induced liver disease?

Alcohol-induced liver disease is
common. But it can be prevented. There are 3 types. Many heavy drinkers progress through
these 3 types over time:

Fatty liver. Fatty liver is the build-up of fat inside the
liver cells. It leads to an enlarged liver. It’s the most common alcohol-induced
liver problem.
Alcoholic hepatitis. Alcoholic hepatitis is an acute
inflammation of the liver. There is death of liver cells, often followed by permanent
scarring.
Alcoholic cirrhosis. Alcoholic cirrhosis is the
destruction of normal liver tissue. It leaves scar tissue in place of the working
liver tissue.

The liver is a large organ that sits up under the ribs on the right side of the belly
(abdomen). The liver:

Helps filter waste from the body
Makes bile to help digest food
Stores sugar that the body uses for energy
Makes proteins that work in many
places in the body—for example, proteins that cause blood to clot

What causes alcohol-induced liver disease?

Alcohol-induced liver disease is caused by heavy use of alcohol. The liver’s job is
to break down alcohol. If you drink more than it can process, it can become badly
damaged.

Fatty liver can happen in anyone who drinks a lot. Alcoholic hepatitis and alcoholic
cirrhosis are linked to the long-term alcohol abuse seen in alcoholics.

Healthcare providers don’t know why some people who drink alcohol get liver disease
while others do not. Research suggests there may be a genetic link, but this is not
yet clear.

What are the symptoms of alcohol-induced liver disease?

The effects of alcohol on the liver
depend on how much and how long you have been drinking alcohol. These are the most
common symptoms:

Fatty liver

Often causes no symptoms
Build-up of fat inside the liver cells
enlarges the liver, causing upper belly (abdomin) discomfort on the right side
Tiredness and weakness
Weight loss

Alcoholic hepatitis

Pain over the liver
Fever
Weakness
Nausea and vomiting
Appetite loss
Poor nutrition
Yellowing of the skin and eyes
(jaundice)

Alcoholic cirrhosis, all of the symptoms
of alcoholic hepatitis and these:

Blood flow through the liver is
limited (portal hypertension)
Enlarged spleen
Poor nutrition
Bleeding in the intestines
Fluid build-up in the belly
(ascites)
Kidney failure
Confusion
Liver cancer

The symptoms of alcohol-induced
liver disease may look like other health problems. Always see a healthcare provider
for
a diagnosis.

How is alcohol-induced liver disease diagnosed?

Your healthcare provider will do a complete health history and physical exam. Other
tests used to diagnose alcohol-induced liver disease may include:

Blood tests. Including liver function tests, which show
whether the liver is working the way it should.
Liver biopsy. This involves removing small tissue samples
from the liver with a needle or during surgery. These samples are checked under a
microscope to find out the type of liver disease.
Ultrasound. This test uses high frequency sound waves to
create a picture of the organs.
CT scan. This imaging test uses X-rays and a computer to
makes detailed images of any part of the body, including the bones, muscles, fat,
and
organs. CT scans are more detailed than general X-rays.
MRI. MRI uses a magnetic field, radio frequency pulses,
and a computer to make detailed pictures of internal body structures. Sometimes
injecting dye into a vein is used to make images of body parts. The dye helps show
the liver and other organs in the belly (abdomen).

How is alcohol-induced liver disease treated?

The goal of treatment is to restore some or all normal functioning to the liver.

You must completely stop drinking
alcohol. This may involve an alcohol treatment program. Sometimes you may also need
to
make changes to your diet. The liver is often able to fix some of the damage caused
by
alcohol so you can live a normal life. The scarring from cirrhosis is sometimes
partially reversible. When liver tissue loss is severe enough to cause liver failure,
most of the damage may be permanent. But the damage won’t have any chance of reversing
if you continue to drink alcohol. Different treatments are needed for different
complications and symptoms of alcoholic liver disease. For example, you may need dietary
changes, vitamins, salt limit, procedures to shrink swollen veins in the digestive
tract, water pills (diuretics), medicines to treat confusion, and anti-inflammatory
medicines.

In some cases, a liver transplant may be considered. But you must complete a rehab
program and go through alcohol detox before this is even an option.

What are possible complications of alcohol-induced liver
disease?

About 3 in 10 people with
alcohol-induced liver disease have hepatitis C virus. Others have hepatitis B virus.
Your provider will test you for both and treat you if needed.

People with alcohol-induced liver disease are also at greater risk for liver cancer.

About half have gallstones.

Those with cirrhosis often develop kidney problems, intestinal bleeding, fluid in
the belly, confusion, liver cancer, and severe infections.

Key points about alcohol-induced liver disease

Alcohol-induced liver disease is a common, but preventable, disease.
Alcohol-induced liver disease is caused by heavy use of alcohol. The liver breaks
down alcohol. If you drink more than it can process, it can become seriously damaged.
The effects of alcohol on the liver depend on how much and how long you have been
drinking.
The most important part of treatment is to completely stop drinking alcohol. Sometimes
diet changes are advised, too.
The liver is often able to repair some of the damage caused by alcohol so that you
can live a normal life. In some cases, liver transplant may be considered. But you
must complete a rehab program and go through alcohol detox before this is even an
option.

Next steps

Tips to help you get the most from a visit to your healthcare provider:

Know the reason for your visit and what you want to happen.
Before your visit, write down questions you want answered.
Bring someone with you to help you ask questions and remember what your provider tells
you.
At the visit, write down the name of a new diagnosis, and any new medicines, treatments,
or tests. Also write down any new instructions your provider gives you.
Know why a new medicine or treatment is prescribed, and how it will help you. Also
know what the side effects are.
Ask if your condition can be treated in other ways.
Know why a test or procedure is recommended and what the results could mean.
Know what to expect if you do not take the medicine or have the test or procedure.
If you have a follow-up appointment, write down the date, time, and purpose for that
visit.
Know how you can contact your provider
if you have questions.

Medical Reviewer: Jen Lehrer MD

Medical Reviewer: Raymond Turley Jr PA-C

Medical Reviewer: L Renee Watson MSN RN

Not what you’re looking for?

90,000 Publications in the media

Nasal bleeding – bleeding from the nasal cavity or nasopharynx.

• Anterior nosebleeds more often arise from the anterior parts of the nasal cavity, usually from the Kisselbach site (an area of the mucous membrane of the nasal septum located 1 cm further than the entrance to the nose, containing a large number of capillaries). The second most common localization is the anterior portions of the inferior turbinate.

• Posterior epistaxis occurs from the posterior portions of the nasal cavity or nasopharynx — usually from the inferior turbinate or fornix of the nasal cavity.

Prevailing age – before 10 and after 50 years.

Etiology • Idiopathic bleeding (most common) • Traumatic bleeding – inaccurate cleaning of the nasal cavity ( epistaxis digitorum ), dry nasal mucosa, foreign body, nasal bone fractures • Upper respiratory tract infections – acute and chronic rhinitis, acute and chronic sinusitis • Vascular anomalies – sclerotic age-related changes in blood vessels, hereditary hemorrhagic telangiectasia, arteriovenous aneurysms • Neoplasms (incl.including tumors of the paranasal sinuses) • Arterial hypertension (usually in combination with other causes) • Pathology of the blood coagulation system – congenital (for example, hemophilia), therapeutic or caused by side effects of drugs, leukemia, platelet dysfunction and other blood pathology • Curvature of the septum ( one side is more susceptible to drying air) • Endometriosis (nasal location of endometriomas).

Clinical picture. Usually external epistaxis.Posterior bleeding may present with hemoptysis, nausea, vomiting of blood, or chalk.

Laboratory research. KLA – signs of hypovolemic shock with massive bleeding or anemia.

Special studies indicated for atypical presentation • X-ray of the paranasal sinuses • Angiography (rare).

Differential diagnostics. Nosebleeds are not an independent nosological form, but a symptom.In less than 10% of cases, it is caused by neoplasms or pathology of the blood coagulation system.

TREATMENT

Mode • Usually outpatient. In case of massive bleeding, hospitalization is indicated • Patients of the elderly and senile age with posterior nosebleeds and tamponade or the use of balloon systems, as a rule, require hospitalization • Bed rest, elevated position of the head end of the bed at an angle of 45–90 °.

Diet. Elimination of alcoholic and hot drinks.

Management tactics • In case of hemorrhagic shock, resuscitation measures are indicated • Sedatives, analgesics, antihypertensive and hemostatic agents – according to indications • The source of bleeding should be determined •• It is necessary to remove liquid blood from the nasal cavity (by suction) and clots (using tweezers or by asking the patient blow your nose) •• To determine the localization, dab the suspicious areas with a damp swab.The presence of several sources indicates a systemic disease. these two areas have different sources of blood supply, which is important for vascular ligation. Determination of localization can be difficult with bilateral bleeding. More often bleeding is unilateral, and the appearance of blood in the opposite half of the nasal cavity is associated with the following factors •• Perforation of the septum •• Throwing of blood through the choanae in the presence of an obstacle to the flow of blood in the anterior regions (tamponade, clamping of the nasal passage) •• Throwing blood through the choanae with posterior bleeding.

Anterior bleeding •• A tampon moistened with a solution of a vasoconstrictor drug and a local anesthetic should be placed in the nasal cavity, and the wings of the nose should be pressed for 5-10 minutes •• Then the tampon should be removed and the vessels examined. It is shown that the solution of silver nitrate is cauterized for 30 s (it must be pressed rather tightly) •• In addition to silver nitrate, it is possible to use chromic acid or 25% trichloroacetyl acid. If large vessels are damaged, electrocoagulation is preferable.Avoid haphazard coagulation of large areas •• If the above measures are unsuccessful, the administration of a second dose of anesthetic and anterior nasal tamponade using a narrow strip of gauze (1–2 cm wide) soaked in vaseline oil to prevent the tampon from drying out. Use tweezers with narrow jaws and a nasal speculum to fit the gauze strip tightly. Laying must be carried out in layers, and each subsequent layer must overlap the previous one (serpentine).

Posterior bleeding •• Traditional posterior nasal tamponade or the use of various balloon systems •• Posterior nasal tamponade technique ••• A tight swab made of tightly rolled gauze pads is tied with two rather thick silk threads ••• The ends of one suture is tied to the catheter , introduced into the nasal cavity from the affected side and excreted through the mouth. The catheter is pulled out of the nose, which forces the tampon against the choanae behind the soft palate. The second thread hangs down from the nasopharynx and subsequently serves to remove the tampon ••• The posterior tamponade is in any case complemented by the anterior one •• Balloon system – an inflatable balloon with or without a central airway ••• Balloons can be of various sizes, as well as for left and right half of the nasal cavity ••• The usual balloon system is represented by small posterior (10 cm ³) and large anterior (30 cm ³) balloons ••• After local anesthesia, the tube is inserted into the affected half of the nasal cavity and advanced into the nasopharynx as probe.Then the posterior balloon is inflated with air or water and advanced in the opposite direction until it is pressed against the choanae. After that, the anterior balloon is inflated (see Complications) ••• A very effective method is the use of a Foley balloon catheter with sizes from 10 to 14 on the Charrier scale. The catheter is passed through the nasal passage into the nasopharynx or the upper part of the oropharynx. It is necessary to make sure that the catheter is not inserted into the lower parts of the pharynx, for which the oral cavity is examined. The balloon is inflated. The catheter is passed in the opposite direction until it covers the area of bleeding.Anterior nasal tamponade is performed as described above. A clamp is applied to the end of the catheter near the nostril. A gauze napkin is placed under the clamp. The end of the catheter is passed behind the ear and secured.

If the above measures are ineffective (heavy bleeding), the following actions are shown •• To achieve adequate compression, sometimes bilateral tamponade is necessary balloon.By subsequent inflation of the balloon, the desired pressure of the tampon on the nasal vault is achieved. •• Severe bleeding requires surgical ligation of the arteries. Ideally, it should be performed after a preliminary examination of the nasal cavity and determination of the localization of bleeding. An alternative method of treatment is angiographic selective embolization of arteries •• The need for blood transfusion depends on the Hb content, CVP value, and vital signs.

Drug therapy • For vasoconstriction of the nasal mucosa – phenylephrine 0.25% solution, xylometazoline (0.1% solution), epinephrine (0.1% solution) • Local anesthetics – aerosol lidocaine, lidocaine gel (2%), lidocaine solution (4%), lidocaine glue (2%) • Some clinicians suggest the use of systemic antibiotics and decongestants to prevent the development of sinusitis with tamponades and the use of balloon systems if there is a need to keep tamponade more than 24 –48 h • In case of significant blood loss – replenishment of iron deficiency.

Observation. Control of hemodynamics according to indications. Tampons and balloon systems are removed after 24-36 hours *

Complications • Sinusitis • Dual balloon systems can move in the direction of the pharynx and if the anterior balloon is not sealed, the posterior balloon can obstruct the airway. Prevention – applying a clamp to the end of the catheter immediately near the nostril after balloon inflation • Hematoma or abscess of the nasal septum due to trauma during packing • Perforation of the septum due to excessive coagulation of the mucous membrane • Necrosis of the mucous membrane due to excessive pressure during anterior or posterior tamponade, balloon inflation (pressure sores with subsequent addition of infection) • Deformation of the outer part of the nose • Intoxication with lidocaine • Vegetative-vascular attacks during tamponation (sneezing, coughing, lacrimation).

Concomitant pathology. In elderly patients – arterial hypertension, atherosclerosis and conditions characterized by a decrease in the functions of the blood coagulation system.

Age characteristics • Children – anterior bleeding is most typical • Elderly – posterior bleeding is most typical.

Prevention. Lubrication of nasal passages with vaseline oil to prevent nasal mucus from drying and crusting, cutting nails.

Synonym. Epistaxis.

ICD-10 • R04.0 Nosebleeds.

90,000 Alcoholic nosebleeds. If a hangover bleeds from a nose Hangover bleeds from a nose

Bleeding after drinking alcohol is not very common. The reasons may vary.

Sometimes they hide on the surface, but sometimes a state of health can provoke an unpleasant symptom.

Most often, blood flows due to mechanical damage to tissues in the nasal cavity.This can happen during a fight, fall, headbutt.

Sometimes prolonged sneezing, a runny nose can provoke a symptom – especially after drinking hard drinks.

If after alcohol bleeding from the nose, you should pay special attention to the state of the circulatory and cardiovascular system.

This phenomenon can be observed in people suffering from high blood pressure. Alcohol products can only increase the jump and thereby provoke the appearance of blood.

Chronic alcohol abuse affects the condition of the blood. Gradually, it becomes more rare. Due to the diluted state, bleeding is possible.

The more often a person abuses alcohol, the higher the likelihood that he will have nosebleeds after alcohol.

In most situations, the problem appears during a hangover, but with prolonged alcoholism, the symptom may occur immediately after a portion of the strong composition.

The likelihood of this problem increases when the following factors are present:

chronic fatigue and lack of sleep;
stress;
migraines;
blood diseases;
low platelets.

It is important not only to figure out why there is a nosebleed after alcohol, but also to know how to help yourself in such a situation qualitatively.

There are many ways to help yourself if you get nosebleeds after alcohol.

There are common misconceptions about self-help methods. Therefore, it is worth understanding how to solve the problem competently from a medical point of view.

The appearance of a cold after drinking alcohol is a temporary phenomenon. Its occurrence is not life threatening. However, nasal congestion causes some discomfort in a person’s well-being.

vasodilating effect of alcohol,

development of alcohol allergy.

After taking alcoholic beverages and getting ethyl alcohol into the blood, vasodilation occurs. An increase in their lumen in the nasal mucosa causes fluid to sweat through the wall. The result is swelling and a runny nose. In the case of strong alcohol intake, the reaction manifests itself quickly. After drinking beer, the congestion will be less pronounced.

The development of an allergic reaction, in addition to the appearance of a runny nose, is characterized by the presence of other signs:

lacrimation,
itching of the mucous membrane of the eyes,
sneezing,
skin manifestations.

In some cases, nasal congestion is not associated with alcohol intake. A runny nose can begin due to ARVI. Usually, it is followed by other symptoms of a cold: the development of a feverish state, a deterioration in the general well-being of a person.

Identification of the root cause of rhinitis determines the specificity of further treatment measures. The vasodilating effect of alcohol goes away after you stop drinking. The occurrence of allergies requires a mandatory visit to a doctor who will prescribe medications.It is necessary to treat a runny nose. Otherwise, it can lead to the development of serious diseases.

Many people experience health complications after drinking alcoholic beverages. For example, a stuffy nose. It can be a symptom of serious diseases of the cardiovascular system or problems with the mucous membranes

Allergic reaction # 8212; one of the causes of nasal congestion

First of all, you must refrain from using ethyl alcohol, or at least stop using vasoconstrictor drugs together with alcohol.

Why does the nose stuff up? This may be due to thinning of the mucous membrane or other problems associated with it.

Polyps develop much faster in people who abuse ethyl alcohol. In its development, this disease goes through several stages:

partial overlap of the upper part of the septum;
almost complete overlap;
full cover.

Each stage can lead to nasal congestion.It is necessary to consult a specialist who will appoint a competent solution to the problem.

Inflammation of the mucous membrane. Alcohol, which is part of alcoholic beverages, is a toxin that quickly enters the bloodstream and spreads throughout the body. As a result, local inflammation develops.

Symptomatic redness of the cheeks and neck while drinking alcohol.

Slight swelling of the upper body.

Intestinal disorder.

Nausea, vomiting, changes in body temperature.

Asthma attacks.

Cough is a reflex sharp exhalation necessary to clear the airways. Its occurrence is due to irritation of the receptors with sputum, nasal mucus, and a foreign body. A sharp exhalation may be due to swelling of the mucous membranes.

Cough is not a disease. It indicates a pathological condition, for example, a disease caused by a viral infection. Cough often develops with chronic alcoholism.This is due to the negative effects of ethanol on the functioning of the respiratory system.

Usually it appears in the morning, it is dry or accompanied by sputum discharge. Sometimes there is a choking cough. In advanced cases, the alcoholic is worried about shortness of breath. At first, it manifests itself during physical activity, then it is felt at rest. The appearance of hemoptysis is not uncommon. This indicates diseases of the respiratory system.

Blood from the nose in hypertensive crisis is a protective reaction of the body,
saving from cerebral hemorrhage.Such a “bloodletting”
allows you to somewhat reduce the off-scale pressure figures and preserve the integrity of the cerebral vessels
. Unfortunately, such a
“fuse” does not work for everyone.

As a rule, drug-induced pressure reduction quickly leads to the cessation of bleeding. For the prevention of nosebleeds, it is extremely important to monitor the pressure level on a daily basis and maintain it at an optimal level using non-drug and medication techniques.

In case of nosebleeds, it is necessary to give the victim a semi-sitting or semi-recumbent position.Throwing the head back allows to somewhat reduce the blood supply to the nasal mucosa. However, it is advisable to avoid swallowing blood, which may run down the back of the pharynx. If bleeding is profuse, it can lead to vomiting.
Cold is applied to the bridge of the nose (cold wet towel, ice bladder, cold water, etc.).
A cotton swab is soaked in 3% hydrogen peroxide solution and gently inserted into the anterior part of the nasal passage. Then the wing of the nose is pressed against the bridge of the nose with a finger for 10-15 minutes.Such measures accelerate thrombus formation in burst capillaries.
Vasoconstrictor drops or spray can be used as an adjunct.
If the performed manipulations did not stop the bleeding, you need to call an ambulance.

According to legend, the greatest warrior
Attila, the leader of the Huns, died from nosebleeds. Probably, his immoderate drunkenness
led to his death, which caused profuse hemorrhage from the vessels
of the nasal cavity.According to the description of the Byzantine historian Priscus Pannia,
Attila died at night, choking on his own blood. On the eve of
, he was celebrating his own wedding and was very drunk.

Alcoholics always know how to answer the question “why?”

The next most important sign of alcoholism: alcoholics know how much they drink. So, they always have a reason that makes them grab a glass. This is a certain holiday, a colleague’s birthday or any other small reason.

If it is not possible to come up with anything, the celebration of any day is used.And in our country it is not difficult. After all, every day there are some name days, in whose name there is always a friend, colleague or relative.

Alcoholics make “stash”

For an alcoholic, alcohol is a kind of elixir, balm or even medicine. Those. that tool that helps to live well and feel as comfortable as possible.

That is why such people make their own stash, i.e. hide alcohol from prying eyes.

And all because they realize that their relatives do not like it and one fine day they may lose access to their coveted fluid.

Minimize

In this article we analyze the problem of nosebleeds after drinking intoxicants: why it appears, how to cope with it, when you can drink alcohol again.

Why can bleeding start after taking alcohol?

The most common cause of nosebleeds is mechanical damage, for example, during a fight. Also, nosebleeds can occur due to high blood pressure, diseases of the circulatory system.Alcohol has a strong effect on the work of the cardiovascular system, pathology appears in the form of expansion of the heart muscle. This problem is accompanied by high blood pressure.

Also, alcohol has the property of thinning the blood, which contributes to the appearance of bleeding from the nose.

Usually, a similar reaction of the body is manifested during a hangover syndrome, but with regular use of intoxicating drinks, it can also occur during a booze. The more often a person drinks alcohol, the more stress on the cardiovascular system and high blood pressure with unpleasant consequences.

In addition to intoxicating drinks, bleeding can be affected by:

Chronic lack of sleep and fatigue.
Not getting enough sleep.
Regular stress.
The appearance of migraine.
Low blood platelet counts.
Poor blood clotting.

How to help with bleeding?

Many people mistakenly believe that the first thing to do is to throw your head back and lie down. This cannot be done.Blood begins to flow into the pharynx, which can lead to its entry into the respiratory tract or gastrointestinal tract. Foreign liquid in the respiratory tract can provoke choking, and blood in the stomach can cause vomiting. After alcohol, bleeding can be eliminated in the following way:

First of all, you need to tilt your head forward. Sit on a hard surface if possible.
You need to press a cold object to your nose; a handkerchief soaked in cool water is perfect.This will help narrow the blood vessels. It is necessary to apply a cold object intermittently – hold for three minutes, remove from the nose for three minutes.
To stop bleeding, you can use cotton wool or a cotton pad soaked in hydrogen peroxide. It must be inserted shallowly into the nostril.
For a quick stop, you will need to use a vasoconstrictor drops. In the absence of such a remedy, you can replace them with fresh lemon juice. It is necessary to instill liquid in the nasal passage using a pharmacy pipette.
Strong pinching of the bridge of the nose with the fingers also helps.

These methods are suitable for eliminating mild bleeding, if the blood goes for more than fifteen minutes and you cannot stop it, it is necessary to resort to tamponade of the nasal cavity. It is done by doctors; it is difficult to cope with the procedure at home. With tamponade, long tourniquets are placed in the nose, which, if necessary, are impregnated with a solution of antibiotics. This treatment can last from one to five days, depending on the reaction of the body.

When can alcohol be consumed after bleeding has been corrected?

Drinking alcohol after stopping blood is not recommended. Repeated drinking of alcoholic beverages can lead to bleeding, which can no longer be eliminated on your own and you will have to seek qualified help from the clinic.

If you want to drink, you will have to wait at least two days after the previous drinking. During this time, the body will have time to recover, and a new portion of intoxicating drinks will not lead to a recurrence of the problem.Doctors advise at all to refrain from alcohol for a week for a complete reboot.

In this article, we analyze the problem of nosebleeds after drinking intoxicating drinks: why it appears, how to cope with it, when you can drink alcohol again.

Also alcohol tends to thin the blood, which contributes to the appearance of nosebleeds.

Usually, a similar reaction of the body is manifested during a hangover syndrome, but with the regular use of intoxicating drinks, it can also occur during a booze. The more often a person drinks alcohol, the more stress on the cardiovascular system and high blood pressure with unpleasant consequences.

Causes of nosebleeds

In addition to intoxicating drinks, bleeding can be affected by:

Chronic lack of sleep and fatigue.
Not getting enough sleep.
Regular stress.
The onset of migraine.
Low blood platelet counts.
Poor blood clotting.

Many people mistakenly believe that the first thing to do is tilt your head back and lie down. This cannot be done.Blood begins to flow into the pharynx, which can lead to its entry into the respiratory tract or gastrointestinal tract. Foreign liquid in the respiratory tract can provoke choking, and blood in the stomach can cause vomiting. After alcohol, bleeding can be eliminated in the following way:

First of all, you need to tilt your head forward. Sit on a hard surface if possible.
You need to press a cold object to your nose, a handkerchief soaked in cool water is perfect.This will help narrow the blood vessels. It is necessary to apply a cold object intermittently – hold for three minutes, remove from the nose for three minutes.
To stop bleeding, you can use cotton wool or a cotton pad soaked in hydrogen peroxide. It must be inserted shallowly into the nostril.
For a quick stop, you will need to use a vasoconstrictor drops. In the absence of such a remedy, you can replace them with fresh lemon juice. It is necessary to instill liquid in the nasal passage using a pharmacy pipette.
Strong pinching of the bridge of the nose with the fingers also helps.

Rules for bleeding from the nose

These methods are suitable for eliminating mild bleeding, if the bleeding is more than fifteen minutes and you cannot stop it, it is necessary to resort to tamponade of the nasal cavity. It is done by doctors; it is difficult to cope with the procedure at home. With tamponade, long tourniquets are placed in the nose, which, if necessary, are impregnated with a solution of antibiotics. This treatment can last from one to five days, depending on the reaction of the body.

Among other things, alcohol has a negative effect on the cardiovascular system. Those who drink a lot for a long time may even experience changes in the heart. Based on these changes, doctors can estimate alcohol consumption and duration. Usually, these pathologies manifest themselves in the form of excessive expansion of the heart muscle and its overgrowth with fat. This phenomenon is known as “beer” or “bullish” heart – when its size becomes larger than normal.But usually, even before such problems arise as a result of alcohol consumption, a person begins to suffer from high blood pressure. At the initial stage, this can only happen during the hangover, and over time on an ongoing basis.

Although insignificant alcohol consumption has a beneficial effect on blood vessels and lowers blood pressure, but slightly exceeding this minimum, we immediately get the opposite effect. There are a number of different reasons why this happens:

As a result of the toxic effects of ethanol on various parts of the nervous system that regulate vascular tone.Alcohol, which is retained in the body and enters the bloodstream, leads to the destruction of red blood cells and knocking them into lumps, which thickens the blood. As a result, the body has to increase the pressure in the blood stream. Drinking alcohol leads to a decrease in the amount of water in the body (dehydration). At the same time, the amount of water in the blood also decreases, which also makes it thicker and provokes an increase in blood pressure. Alcohol disrupts the adrenal glands and increases the adrenaline levels they are responsible for.This is especially true in the first days after heavy drinking. Epinephrine increases blood pressure. Long-term drinkers often suffer from kidney health problems. And this paired organ is known to take a very active part in the regulation of arterial blood pressure.

Some of these factors can cause an increase in blood pressure in the short term, which is more pronounced during a hangover. Others lead to the development of hypertension as a permanent disease.

Hypertension is quite common among people who drink. According to scientists, more than 40% of people who regularly drink alcohol suffer from it.

Hangover or high blood pressure?

High blood pressure is not always observed after drinking alcohol, especially in a still healthy person. It is often possible to confuse the symptoms of high blood pressure with those of a common hangover. To do this, below is a table with a list of the main common symptoms of both phenomena.

07 Jun 2019

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But there are a number of symptoms that are usually inherent in only one thing – either high blood pressure or a hangover.

Still, the best way to find out if high blood pressure is to measure it with a tonometer. This will help you know for sure if problems are being observed with this very important indicator of health. And as mentioned above, the first “bells” can come during a hangover and you should not allow this to develop into permanent hypertension.It’s better to give up alcohol completely, because it’s not worth it.

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Causes of nosebleeds

Not enough sleep.
Regular stress.
The onset of migraine.
Poor blood clotting.

The effect of alcohol on the heart and blood vessels.mp4

The pressure from alcohol jumps:

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Quite often it is difficult to get out of hard drinking on your own. Therefore, medications are used for treatment. An increase in blood pressure is becoming one of the main health consequences.

With serious and prolonged binge drinking there is a risk of heart attack, stroke, delirium tremens, epilepsy. This is explained by the presence of high blood pressure, which greatly increases the load on the cardiovascular system.

In a few days, a specialist, using medications, will take the patient out of the binge state without risk and health complications. In this case, blood pressure will normalize, heart rate will return to normal, nausea and headache will disappear, sleep and appetite will stabilize.Medicines are selected taking into account the existing diseases and the state of health of the patient.

The drugs and medicines used are harmless and effective, they help to eliminate the lack of vitamins and minerals, fluid in the body.

High blood pressure most often accompanies the hangover syndrome. When withdrawal symptoms are removed, a large volume of fluid is injected, which provokes an increase in blood pressure. In some cases, drugs are used in dropper systems that normalize and stabilize pressure.

If headaches are present during withdrawal from hard drinking, it is recommended to use ketanol, spazmalgon, nurofen and analgin.

It is recommended to constantly monitor your blood pressure. If the systolic blood pressure exceeds 140 mm Hg, then the patient needs to use ACE inhibitors, that is, enalapril – 5-10 mg or lisinopril (diroton) – 5 mg. Throughout the treatment, blood pressure is constantly monitored.

Choosing the right treatment and timely seeking medical help will help you get rid of alcohol addiction and the consequences, in particular high blood pressure.You should not experiment on your own with the choice and administration of drugs, the alcoholic liver may not be able to cope, and the health consequences can be detrimental. The course of treatment must be prescribed by a doctor!

Blood from the nose in medical terminology is called epistaxis. This phenomenon is considered quite common, and the reasons why the nose bleeds can be very diverse. Deviation occurs in both the adult and the child.

Often this kind of damage is the result of mechanical damage to the integrity of the nose after a blow, bruise, fall from a height.But it also happens in a person who has not been exposed to external negative influences, the blood runs every day. Then the presented deviation should not only be looked for, how to stop, but also be additionally examined for diseases, with bleeding as the main symptom.

If blood started to flow during pregnancy, at night in a teenager, or just when blowing your nose, you should first give the victim first aid. But when the phenomenon repeats on a regular basis in the morning and does not stop for a long time, then this is a reason to refuse treatment at home.It will be more effective to contact a therapist who will tell you what to do in such emergency situations, and also tell you what kind of diagnostics will allow you to understand what the repeated pathological signs mean.

Schematically, all bleeding with nasal localization can be divided into two categories: front, back. The presented filtering format is based on human physiology. Many people wonder if it can happen that both types are combined. This option takes place with extensive injuries.Only knowing how to call an ambulance and the rules of emergency assistance will help here.

According to medical statistics, blood often flows from the Kisselbach plexus, which includes it in the anterior region. About 90% of clinical cases involve damage to the dense submucosal cavernous venous network. It hides small capillaries, arterioles, designed to provide the anterior section of the cartilage with sufficient nutrition. If blood flows from one nostril, comes out in drops, then most likely this indicates damage to the plexus.

There are no particularly complex actions on how to make epistaxis less significant here. If everything is fine with coagulability, then the red crusts are baked in a few minutes. A side effect may be dryness inside the cavity, as well as complaints of a headache. Severe headache also occurs with low blood pressure. Then local therapy, as with a cold, cannot be dispensed with. Complex treatment will be required, which can last more than one year. An identical approach is provided if the patient is diagnosed with chronic high blood pressure.

Much less often, in about 10% of the total number of cases, epistaxis begins due to damage to the large arterial branches, or the middle part of the nose. With significant damage, even bleeding from the mouth, ears, and eyes is possible. A similar deviation is recorded not only in adult men, but also in rats and cats.

Suddenly onset, profuse blood loss can even lead to death if you do not provide assistance in time. The jet enters the throat, blocking normal breathing, causing suffocation.

Another format for classifying the anomaly is the division by volume of how much blood is poured, to which snot is sometimes added:

In the first case, girls or the elderly lose only a few milliliters. This very often happens with a cold, when you blow your nose, when you sneeze. After a couple of minutes, only a dried red crust reminds of an unpleasant incident.

This is explained by the fact that at temperature constantly functioning vessels fail faster.Immunomodulating therapy is needed here, which will eliminate problematic symptoms at a fundamental level.

Of the consequences, only the fact that the patient can be haunted by a characteristic “iron” smell, as well as a panic that grips little girls due to an unexpected onset of an attack, is singled out here.

When the liquid leaves in clots, but the total volume is no more than 700 milliliters, and the patient complains of a sharp deterioration in health, then these are signs of mild severity.In total, a person at this stage will not lose more than 12% of the total amount of biological fluid. The phenomenon is diagnosed with sinusitis, when the nose is stuffy, and then the doctors began to wash the sinuses. Epistaxis of this type also provides that, together with the cow, the remaining pus came out, which no pills can extract.

Other markers of moderate degree of damage are called:

weakness;
dizziness;
flies before the eyes;
rapid heart rate.

This is possible even in babies, cats, in early pregnancy in women.

Average degree includes blood loss up to one and a half liters. Only knowing which doctor to go to will help here, because even after half an hour it does not get better. Here it will be necessary to cover losses until the doctor arrives at the scene. Believe the advice of the townsfolk that they post on the forum, especially not worth it. It is necessary to immediately seek qualified help, since other symptoms manifest themselves against the background of the main symptom:

Epistaxis of a severe form involves the loss of more than 20% of the total amount of biological fluid.An attack can begin during sleep, in the evening and not go away for a long time. It will not be possible to block such a flow on its own, therefore, the stop must be made by specialists.

Massive blood loss has a bad effect on changes in blood pressure, which is why the victim is faced with hemorrhagic shock. He becomes inhibited, suffers from impaired consciousness, an acute deficiency in the supply of nutrients to the internal organs, which causes fainting within a few minutes.

This option can happen both in a boy who has a stroke and in an adult. If nothing is done, then death is inevitable. Difficulties are added by the fact that the victim is tormented by a cough, the dark thick liquid does not dry, pouring down the throat.

Nasal bleeding provocateurs

Most of the inhabitants at times encounter this symptom, which occurs with ARVI, blowing your nose with strong pressure, after hitting your face. To consider all the most common primary sources of why one unexpectedly has to deal with epistaxis, doctors divided them into two camps:

Local factors include trauma, which often happens to those who drink alcohol in excessive amounts.During drunkenness, a person is less able to orientate himself in space, which leads to falls.

The same outcome awaits those who have unsuccessfully removed the nasal crusts. Sometimes, when scratching from the inside of the cavity, just a yellow ichor stands out. This also indicates that there was an injury to the mucous membrane.
The local category includes the differential barometric pressure, which is characteristic of people with unusual professions such as pilots or climbers. But their feeling of congestion does not cause serious panic, because experts are preliminary working to strengthen the system by taking vitamins.Additionally, people with dangerous professions pass a special analysis.

Among other aspects of this kind, found even in the third trimester of pregnancy, there are:

congestion of the mucous membrane, which happens from drops;
inhalation of narcotic substances, which additionally negatively affect the heart, liver;
congenital pathologies such as curvature of the nasal septum, which guarantees bleeding at least several times a year;
malignant, benign oncological neoplasms.

Moreover, with cancer, there are options when black blood just drips from the nose a little, which even the number one folk remedy – hydrogen peroxide – will not stop. And it also happens that a person began to be additionally disturbed by nausea, a feeling as if the nose was clogged, profuse blood loss. Ordinary vasoconstrictor drugs will not help here. You will have to undergo extensive diagnostics so that the doctor will prescribe specific pills, a course of chemotherapy, if necessary.

Among other causes of an atypical nature, there are inhalation of cold air, sunstroke, which also makes you sick, surgery, incorrect installation of an oxygen catheter.

But if local factors prevail in a kitten, rat, rabbit, calf and other animals, then most people are still victims of systemic aspects. They even apply to a newborn baby, a one-year-old son, daughter, husband, elderly grandparents, a woman carrying a fetus at 40 weeks. Here, the norm indicators deviate due to:

arterial hypertension;
allergies;
vascular lesions, which are outwardly expressed in the fact that the bruises do not go away for a long time;
blood diseases that become deadly even if a person simply opened the nasal cavity;
alcohol abuse;
vitamin deficiency;
heart ailments, against which hemoglobin also falls.

Slightly less often, epistaxis happens right in the classroom, and the victim does not have the slightest idea what is the reason for this. Doctors recommend that such patients undergo diagnostics in order to search for connective tissue diseases. A correctly drawn up program of what to take will literally save the patient from the blood stream.

A large percentage of clinical cases fall on epistaxis, provoked by:

taking non-steroidal anti-inflammatory drugs;
hemophilia;
hemorrhagic diathesis;
kidney disease;
infectious diseases such as HIV;
hormonal disruptions.

Doctors note that sometimes problems are closely related to psychosomatics, when a girl starts to get nervous before her period. There are also patients who complain that they ooze ichor from the nasal sinuses only in the spring. But this does not mean that it is dangerous for such victims to go outside at this time of the year. Most likely, a little blood is released due to the classic spring vitamin deficiency, and the situation is aggravated each time the cavity is rinsed in order to get rid of allergenic particles of plant pollen.

Some people complain that brown blood gushed out after coffee, which makes them think that the victim was a victim of cancer. In fact, this hardly hints at a polyp, but only hints about problems with blood pressure, because caffeine is a strong stimulant of changes in blood pressure indicators. If you overdo it with the strength of the drink, you can even earn a fainting spell, which is important for hypertensive patients.

First aid measures

When it comes to the release of biological fluid after a puncture, where there is no risk of gushing blood flow from the ears, you can get by with the provision of first aid at home.

The most important thing is never to follow the popular advice that you should throw your head back. This will only worsen the overall clinical picture. It is better to postpone folk remedies, and instead put the person on the bed, slightly raising the head end of the bed, and turn his head to one side. When tilting, it will be possible to open the airways into which secretions can enter.

If there was no concussion, and the losses are minimal, then it is enough:

to provide an inflow of fresh air;
Apply cold to the bridge of the nose.

If the incident happened in winter, then you can even use the snow by putting it in a bag and placing it on the bridge of your nose. You can hold the cold bag for no more than ten minutes. It is forbidden to blow your nose, as well as to swallow blood. When the characteristic taste persists, then the accumulation of saliva, mucus with bloody clots is spit out.

It is worthwhile to act in the same way if heat, a weak blow, a condition when you are sick became the catalyst for a deterioration in well-being. When it pours after a weightlifter’s workout, the powerlifter should follow the standard algorithm.

But if the stream literally as a fountain has been going on for an hour, then more radical measures must be taken. These involve making a sterile cotton swab soaked in 3% hydrogen peroxide.

In case of sunstroke received at school, on the beach, a person is transported to a cool place by placing a wet cold cloth on his face. Ice is applied to the bridge of the nose to cool the hot skin as soon as possible.

According to the standard instructions, you need to act if a problem occurs when you cry, quit smoking and the body is rebuilt due to allergies.When crying, you don’t even have to look for something to drink, it is enough to help locally, periodically coughing up the blood accumulating in the oral cavity.

But if your head is spinning, purulent discharge is traced, pink blood is constantly gushing, fatigue is stifled, as if from a hangover, then you should not delay visiting a doctor.

Providing care in a hospital setting

Pet owners like a hamster always take their pets to the vet after they are bleeding, but often ignore their own diagnosis.

In order not to reach the point when the back of the head is literally about to fall apart, and the temples are cracking, you need to see a doctor in time. The group of particular risk includes those who additionally complain of diarrhea, suffer from otitis media, cirrhosis. Sometimes, uncontrolled blood flow is a side effect of labor stress. Regardless of what was the primary source of the defeat, you need to see a specialist. He will prescribe a diagnosis after first aid in a hospital setting.Tests include platelet counts, other specific tests.

A tamponade will be made to the victim on the spot. This is the name of the introduction of tampons, previously prescribed hemostatic agents, directly into the nasal cavity. In the absence of significant progress, cauterization of bleeding vessels is possible. An unusual ointment, or rather, a liquid acid-based product, can help in this.

In some clinics, it is preferred to use ultrasonic disintegration, laser therapy instruments, liquid nitrogen, and electrocoagulation on the walls of the affected vessels.

It’s one thing when a child managed to break his nose and cut his gums. Local treatment is required here, because the situation is unlikely to be repeated on a daily basis. But when unpleasant symptoms make themselves felt too often, then you need to seek the advice of a therapist.

Otherwise, the feeling of discomfort, accompanied by a nasty aftertaste, will quickly become the cause of a general breakdown. The systematic repetition of the clinical picture is a signal from the body that some kind of disease has struck the organs.The victim’s task is to find the source of the pathology at an early stage of development.

In this article we analyze the problem of nosebleeds after drinking intoxicating drinks: why it appears, how to cope with it, when you can drink alcohol again.

Why can bleeding start after taking alcohol?

Also alcohol tends to thin the blood, which contributes to the appearance of nosebleeds.

Causes of nosebleeds

In addition to intoxicating drinks, bleeding can be affected by:

Chronic lack of sleep and fatigue.
Not getting enough sleep.
Regular stress.
The onset of migraine.
Low blood platelet counts.
Poor blood clotting.

How to help with bleeding?

Many people mistakenly think that the first thing to do is tilt your head back and lie down.This cannot be done. Blood begins to flow into the pharynx, which can lead to its entry into the respiratory tract or gastrointestinal tract. Foreign liquid in the respiratory tract can provoke choking, and blood in the stomach can cause vomiting. After alcohol, bleeding can be eliminated in the following way:

First of all, you need to tilt your head forward. Sit on a hard surface if possible.
You need to press a cold object to your nose, a handkerchief soaked in cool water is perfect.This will help narrow the blood vessels. It is necessary to apply a cold object intermittently – hold for three minutes, remove from the nose for three minutes.
To stop bleeding, you can use cotton wool or a cotton pad soaked in hydrogen peroxide. It must be inserted shallowly into the nostril.
For a quick stop, you will need to use a vasoconstrictor drops. In the absence of such a remedy, you can replace them with fresh lemon juice. It is necessary to instill liquid in the nasal passage using a pharmacy pipette.
Strong pinching of the bridge of the nose with the fingers also helps.

Rules for bleeding from the nose

When can I drink alcohol after eliminating bleeding?

Although quite unpleasant, most nosebleeds are not serious. Nosebleeds occur more often than the person himself notices – sometimes they stop very quickly, not even a drop of blood has time to flow out. The tiny blood vessels in the nose are close to the surface, making them vulnerable. These blood vessels can rupture due to irritation or injury.A nosebleed usually does not require medical attention.

Nose bleeding can be caused by a wide variety of causes.

High blood pressure

Frequent nosebleeds may be associated with high blood pressure. The American Heart Association suggests checking your blood pressure if you have frequent nosebleeds for no apparent reason. Abnormally high blood pressure requires medical attention.

Dry air

Many sources indicate that dry air irritates the nasal mucosa.Dry areas appear inside the nose – on the mucous membrane. This causes discomfort, the person begins to clear the nose, friction violates the integrity of the mucous membrane, causing bleeding. Blood from the nose often comes in the winter, because the air in the room is very dry.

Drug use

Certain medicines, such as aspirin, ibuprofen, and some others, thin the blood and may increase the risk of nosebleeds. If you are taking any medications, read the instructions.It is possible that nosebleeds are a side effect.

Smoking

Smoking, like dry air, can dry out nasal membranes, causing nosebleeds. Secondhand smoke can also cause bleeding, experts say.

Alcohol consumption

Excessive alcohol consumption can lead to nosebleeds. Alcohol dilates blood vessels, and the rate of blood clotting can also change – the number of platelets decreases.Moderate alcohol consumption usually does not have this deleterious effect on the body.

Diseases

Allergies, colds, whooping cough and sinusitis, sinus infections are common causes of nosebleeds. More serious conditions such as leukemia, hemophilia, rheumatism, arterial sclerosis, and nasal tumors can also cause bleeding. If the causes of the phenomenon are not clear, and nosebleeds are frequent, a visit to the doctor is recommended to rule out serious illness.

Injury

As we all know, an injury or blow to the nose often causes bleeding. This type of bleeding is usually not dangerous. It is recommended to see a doctor if the nose has acquired an irregular shape, or if the bleeding does not stop within ten minutes.

Structural abnormalities

The cartilage that separates the two sides of the nose, the nasal septum, may be crooked. This can happen as a result of minor trauma at a young age.As the child grows, a crooked septum can worsen health, sometimes leading to difficulty breathing and nosebleeds. Check the condition of the nasal septum.

Vitamin K deficiency

Vitamin K helps to form blood clots that stop bleeding. The human body produces vitamin K, but not in the amount required. You need to get this vitamin from food. Green leafy vegetables such as spinach, broccoli, Brussels sprouts, asparagus, and lettuce are good sources of vitamin K.Children who do not eat green vegetables are more likely to have a vitamin K deficiency, which can lead to frequent nosebleeds.

Among other things, alcohol has a negative effect on the cardiovascular system. Those who drink a lot for a long time may even experience changes in the heart. Based on these changes, doctors can estimate alcohol consumption and duration. Usually, these pathologies manifest themselves in the form of excessive expansion of the heart muscle and its overgrowth with fat.This phenomenon is known as “beer” or “bullish” heart – when its size becomes larger than normal. But usually, even before such problems arise as a result of alcohol consumption, a person begins to suffer from high blood pressure. At the initial stage, this can only happen during the hangover, and over time on an ongoing basis.

Although insignificant alcohol consumption has a beneficial effect on blood vessels and lowers blood pressure, but slightly exceeding this minimum, we immediately get the opposite effect.There are a number of different reasons why this happens:

As a result of the toxic effects of ethanol on various parts of the nervous system that regulate vascular tone.
Alcohol, which remains in the body and gets into the bloodstream, leads to the destruction of red blood cells and knocking them into lumps, which thickens the blood. As a result, the body has to increase the pressure in the blood stream.
Drinking alcohol leads to a decrease in the amount of water in the body (dehydration).At the same time, the amount of water in the blood also decreases, which also makes it thicker and provokes an increase in blood pressure.
Alcohol disrupts the adrenal glands and increases the adrenaline levels they are responsible for. This is especially true in the first days after heavy drinking. Epinephrine increases blood pressure.
Long-term drinkers often suffer from kidney problems. And this paired organ is known to take a very active part in the regulation of arterial blood pressure.

Hangover or high blood pressure?

High blood pressure is not always observed after drinking alcohol, especially in a still healthy person. It is often possible to confuse the symptoms of high blood pressure with those of a common hangover.To do this, below is a table with a list of the main common symptoms of both phenomena.

Why can blood pressure rise after drinking alcohol?

Although insignificant alcohol consumption has a beneficial effect on blood vessels and lowers blood pressure, but slightly exceeding this minimum, we immediately get the opposite effect.There are a number of different reasons why this happens:

As a result of the toxic effects of ethanol on various parts of the nervous system that regulate vascular tone. Alcohol, which is retained in the body and enters the bloodstream, leads to the destruction of red blood cells and knocking them into lumps, which thickens the blood. As a result, the body has to increase the pressure in the blood stream. Drinking alcohol leads to a decrease in the amount of water in the body (dehydration). At the same time, the amount of water in the blood also decreases, which also makes it thicker and provokes an increase in blood pressure.Alcohol disrupts the adrenal glands and increases the adrenaline levels they are responsible for. This is especially true in the first days after heavy drinking. Epinephrine increases blood pressure. Long-term drinkers often suffer from kidney health problems. And this paired organ is known to take a very active part in the regulation of arterial blood pressure.

Some of these factors can cause an increase in blood pressure in the short term, which is more pronounced during a hangover.Others lead to the development of hypertension as a permanent disease.

Hypertension is quite common among people who drink. According to scientists, more than 40% of people who regularly drink alcohol suffer from it.

Hangover or high blood pressure?

Vkontakte

Odnoklassniki

Among other things, alcohol also has a negative effect on the cardiovascular system. Those who drink a lot for a long time may even experience changes in the heart. Based on these changes, doctors can estimate alcohol consumption and duration. Usually, these pathologies manifest themselves in the form of excessive expansion of the heart muscle and its overgrowth with fat. This phenomenon is known as “beer” or “bullish” heart – when its size becomes larger than normal.But usually, even before such problems arise as a result of alcohol consumption, a person begins to suffer from high blood pressure. At the initial stage, this can only happen during the hangover, and over time on an ongoing basis.

As a result of the toxic effects of ethanol on various parts of the nervous system that regulate vascular tone.
Alcohol, which remains in the body and gets into the bloodstream, leads to the destruction of red blood cells and knocking them into lumps, which thickens the blood. As a result, the body has to increase the pressure in the blood stream.
Drinking alcohol leads to a decrease in the amount of water in the body (dehydration). At the same time, the amount of water in the blood also decreases, which also makes it thicker and provokes an increase in blood pressure.
Alcohol disrupts the adrenal glands and increases the adrenaline levels they are responsible for.This is especially true in the first days after heavy drinking. Epinephrine increases blood pressure.
Long-term drinkers often suffer from kidney problems. And this paired organ is known to take a very active part in the regulation of arterial blood pressure.

Some of these factors can cause an increase in blood pressure in the short term, which is more pronounced during a hangover.Others lead to the development of hypertension as a permanent disease.

Hangover or high blood pressure?

In this article we analyze the problem of nosebleeds after drinking intoxicating drinks: why it appears, how to cope with it, when you can drink alcohol again.

Why can bleeding start after taking alcohol?

The most common cause of nosebleeds is mechanical damage, for example, during a fight. Also, nosebleeds can occur due to high blood pressure, diseases of the circulatory system. Alcohol has a strong effect on the work of the cardiovascular system, pathology appears in the form of expansion of the heart muscle. This problem is accompanied by high blood pressure.

Also alcohol tends to thin the blood, which contributes to the appearance of nosebleeds.

Causes of nosebleeds

In addition to intoxicating drinks, bleeding can be affected by:

Chronic lack of sleep and fatigue.
Not getting enough sleep.
Regular stress.
The onset of migraine.
Low blood platelet counts.
Poor blood clotting.

How to help with bleeding?

Many people mistakenly think that the first thing to do is tilt your head back and lie down. This cannot be done. Blood begins to flow into the pharynx, which can lead to its entry into the respiratory tract or gastrointestinal tract. Foreign liquid in the respiratory tract can provoke choking, and blood in the stomach can cause vomiting.After alcohol, bleeding can be eliminated in the following way:

First of all, you need to tilt your head forward. Sit on a hard surface if possible.
You need to press a cold object to your nose, a handkerchief soaked in cool water is perfect. This will help narrow the blood vessels. It is necessary to apply a cold object intermittently – hold for three minutes, remove from the nose for three minutes.
To stop bleeding, you can use cotton wool or a cotton pad soaked in hydrogen peroxide.It must be inserted shallowly into the nostril.
For a quick stop, you will need to use a vasoconstrictor drops. In the absence of such a remedy, you can replace them with fresh lemon juice. It is necessary to instill liquid in the nasal passage using a pharmacy pipette.
Strong pinching of the bridge of the nose with the fingers also helps.

Rules for bleeding from the nose

These methods are suitable for eliminating mild bleeding, if the bleeding is more than fifteen minutes and you cannot stop it, it is necessary to resort to tamponade of the nasal cavity.It is done by doctors; it is difficult to cope with the procedure at home. With tamponade, long tourniquets are placed in the nose, which, if necessary, are impregnated with a solution of antibiotics. This treatment can last from one to five days, depending on the reaction of the body.

When can I drink alcohol after eliminating bleeding?

If you want to drink, you will have to wait at least two days after the previous drinking. During this time, the body will have time to recover, and a new portion of intoxicating drinks will not lead to a recurrence of the problem. Doctors advise at all to refrain from alcohol for a week for a complete reboot.

Quite often it is difficult to get out of the binge on your own. Therefore, medications are used for treatment. An increase in blood pressure is becoming one of the main health consequences.

Why are high blood pressure dangerous after prolonged drunkenness?

The drugs and medicines used are harmless and effective, they help to eliminate the lack of vitamins and minerals, fluid in the body.

After cleansing the body, pressure may jump. What is the reason for this?

High blood pressure most often accompanies the hangover syndrome. When withdrawal symptoms are removed, a large volume of fluid is injected, which provokes an increase in blood pressure.In some cases, drugs are used in dropper systems that normalize and stabilize pressure.

If headaches are present during withdrawal from hard drinking, it is recommended to use ketanol, spazmalgon, nurofen and analgin.

It is recommended to constantly monitor your blood pressure. If the systolic blood pressure exceeds 140 mm Hg, then the patient needs to use ACE inhibitors, that is, enalapril – 5-10 mg or lisinopril (diroton) – 5 mg.Throughout the treatment, blood pressure is constantly monitored.

Choosing the right treatment and timely seeking medical help will help you get rid of alcohol addiction and the consequences, in particular high blood pressure. You should not experiment on your own with the choice and administration of drugs, the alcoholic liver may not be able to cope, and the health consequences can be detrimental. The course of treatment must be prescribed by a doctor!

Although quite unpleasant, most nosebleeds are not serious.Nosebleeds occur more often than the person himself notices – sometimes they stop very quickly, not even a drop of blood has time to flow out. The tiny blood vessels in the nose are close to the surface, making them vulnerable. These blood vessels can rupture due to irritation or injury. A nosebleed usually does not require medical attention.

Nose bleeding can be caused by a wide variety of causes.

High blood pressure

Frequent nosebleeds may be associated with high blood pressure.The American Heart Association suggests checking your blood pressure if you have frequent nosebleeds for no apparent reason. Abnormally high blood pressure requires medical attention.

Dry air

Many sources indicate that dry air irritates the nasal mucosa. Dry areas appear inside the nose – on the mucous membrane. This causes discomfort, the person begins to clear the nose, friction violates the integrity of the mucous membrane, causing bleeding.Blood from the nose often comes in the winter, because the air in the room is very dry.

Drug use

Smoking

Smoking, like dry air, can dry out nasal membranes, causing nosebleeds.Secondhand smoke can also cause bleeding, experts say.

Alcohol consumption

Excessive alcohol consumption can lead to nosebleeds. Alcohol dilates blood vessels, and the rate of blood clotting can also change – the number of platelets decreases. Moderate alcohol consumption usually does not have this deleterious effect on the body.

Diseases

Allergies, colds, whooping cough and sinusitis, sinus infections are common causes of nosebleeds.More serious conditions such as leukemia, hemophilia, rheumatism, arterial sclerosis, and nasal tumors can also cause bleeding. If the causes of the phenomenon are not clear, and nosebleeds are frequent, a visit to the doctor is recommended to rule out serious illness.

Injury

Structural abnormalities

The cartilage that separates the two sides of the nose, the nasal septum, may be crooked. This can happen as a result of minor trauma at a young age. As the child grows, a crooked septum can worsen health, sometimes leading to difficulty breathing and nosebleeds. Check the condition of the nasal septum.

Vitamin K deficiency

Vitamin K helps to form blood clots that stop bleeding.The human body produces vitamin K, but not in the amount required. You need to get this vitamin from food. Green leafy vegetables such as spinach, broccoli, Brussels sprouts, asparagus, and lettuce are good sources of vitamin K. Children who don’t eat green vegetables are more likely to be deficient in vitamin K, which can lead to frequent nosebleeds.

90,000 FAQ – recovery after septoplasty

Tsvetnoy Boulevard

Moscow, Samotechnaya, 5

around the clock

Preobrazhenskaya Square

Moscow, B.Cherkizovskaya, 5

Daily

from 09:00 to 21:00

Day off:

January 1, 2020

Dmitry Donskoy Boulevard

Moscow, Green, 28 building 1

Daily

from 09:00 to 21:00

Michurinsky prospect

Moscow, Bolshaya Ochakovskaya, 3

Daily

from 09:00 to 21:00

Information

eighteen.11.2021

SCHEDULE OF LESSONS ON THE Rink 68 Cherepanovs Drive

08.11.2021

Address list of facilities for organizing recreation of the population on the territory of the Koptevo district

09.04.2021

Monthly work plan of sports sections on the territory of the “Koptevo” district of the Northern Administrative District of Moscow, April 2021.

09.04.2021

Monthly plan of regional mass sports and physical culture and recreation activities with the population at the place of residence in the period from “01” to “30” April 2021 in the Koptevo district

08.04.2021

SCHEDULE OF CLASSES ON THE INDOOR SPORTS AREA OF THE SPORTS COMPLEX “BRIGANTINA”

24.03.2021

Dear residents of the Koptevo district!

Due to the onset of positive outside temperatures,
from 25.03.2021 the work of artificial ice skating rinks will be completed

05.03.2021

SCHEDULE OF RACING CLASSES (from 09.03.2021)

04.03.2021

March 8, 2021 skating rink at the address: Cherepanovyh proezd, 68 will be open to visitors

04.03.2021

March 07, 2021 from 11.30 to 13.30 on the skating rink at the address: Cherepanovyh proezd, 68 will host a regional sports festival

02.03.2021

Dear residents! March 3, 2021 from 17.00 to 19.00 at the skating rink at the address: Cherepanovyh proezd, 68

01.03.2021

On March 2, 2021, from 15.00 to 18.00 at the skating rink at the address: 68 Cherepanovyh proezd, a training session of the national ice hockey team of the Northern Administrative District will take place as part of the Moscow Courtyard – Sports Courtyard Spartakiad

03.02.2021

SKATING SCHEDULE

29.01.2021

At the skating rink at 68 Cherepanovyh proezd, district hockey competitions will take place as part of the Moscow Courtyard – Sports Courtyard Spartakiad Games

26.01.2021

On January 27, 2020, from 18.00 to 20.00, at the skating rink at the address: Cherepanovyh proezd, 68, district hockey competitions will take place as part of the Moscow Dvor – Sports Dvor Spartakiad

thirty.12.2020

Dear visitors! At the skating rink at the address: Cherepanovyh proezd, 68

some hockey sections
State Budgetary Institution of the city of Moscow “Physical culture and leisure center” Brigantina “is not held.

17.12.2020

Dear visitors of the skating rink on Cherepanovs Passage 68!

09.12.2020

Skating rink at the address: Cherepanovyh proezd, 68 from December 14, 2020 will work according to a new schedule

09.12.2020

First aid at the rink

What to do if …

09.12.2020

ROCKER RULES

01.12.2020

Schedule of lessons at the skating rink Proezd Cherepanovs, d. 68

90,000 Alcoholic cirrhosis of the liver. Transition of alcoholic liver disease to cirrhosis.

Transition of alcoholic liver disease to cirrhosis

The transformation of alcoholic liver disease into cirrhosis is the terminal stage of the disease.The incidence of cirrhosis of the liver increases with an increase in the alcohol dose of more than 30 ml / day and is maximal with the use of 120 ml / day or more.

The transition of alcoholic liver disease to cirrhosis occurs in cases where the patient has not stopped drinking alcohol in any doses, has not undergone treatment for alcoholic liver disease, does not adhere to strict recommendations for nutrition and vitamin therapy.

What is the danger of cirrhosis in alcoholic liver disease?

As the disease progresses, normal healthy liver cells are gradually destroyed and replaced with non-functioning dense adipose tissue.Liver failure develops, portal hypertension forms with possible complications – ascites (fluid in the abdominal cavity) and internal bleeding.

Insufficiency of liver function is manifested in a violation of its ability to detoxify, which leads to an increase in the blood of toxic metabolic products, including bilirubin, ammonia, bile acids. Since these substances are primarily toxic to the nervous system, encephalopathy develops. Itching of the skin is also possible.

Dense liver tissue interferes with normal internal circulation and causes an increase in pressure in the portal vein. In this case, there is an increase in the spleen and the expansion of the veins of the esophagus. The increase in pressure in the internal vessels causes fluid to appear in the abdominal cavity (ascites) due to the permeability of the blood vessels under the influence of high pressure. Vascular rupture and internal bleeding are life threatening.

Surgical vascular ligation is sometimes performed to prevent this critical development.However, the development of the pathological process can only be stopped by treating alcoholic cirrhosis.

Treatment of alcoholic cirrhosis

First of all, patients with alcoholic cirrhosis need a life-long refusal from alcohol . This is a prerequisite for opportunities to receive recovery as a result of treatment. It is also extremely important to provide a complete balanced dietary nutrition with the introduction of the required amount of vitamins.

The main goal of treatment is to correct liver function. Violation of the protein-synthesizing function of the liver is life-threatening, therefore, it is necessary to replenish the lack of albumin in the body with the help of droppers (preferably in a hospital under the supervision of a doctor). Albumin solution replacement therapy is carried out according to the standard scheme.

In the presence of ascites or edema, it is necessary to prescribe diuretics, the dose of which is selected individually, taking into account the control of the body’s water balance.

Often, liver failure is accompanied by cholestasis, which occurs when the detoxifying function of the liver is impaired and is characterized by an increase in the level of bilirubin and bile acids in the blood. In this case, the appearance of excruciating itching is possible, for the correction of which ursodeoxycholic acid is prescribed.

For the restoration of liver cells, Heptral is recommended at a dose of 1200 g per day for a year or more.

If liver failure is accompanied by damage to other internal organs – kidneys, pancreas, heart, then appropriate specialists should be involved in the treatment.

Can alcoholic cirrhosis of the liver be cured?

The prognosis of the course of the disease and the results of treatment is largely determined by the stage of the disease and the degree of liver damage, with which the patient turns to a specialist.

In severe alcoholic liver disease and cirrhosis, the prognosis is different and not always hopeless.

The first and most important condition for survival is a complete refusal to use any dose of alcohol, proper nutrition and intake of vitamins.

In case of a disease with a poor prognosis (high Maddray index – survival within 30 days)), prednisolone is prescribed at a dose of 40 mg / day for two weeks, then the dose is reduced within two weeks until complete cancellation.

Drug treatment is aimed at restoring the structure of the liver tissue destroyed by alcohol and restoring its function. For this, long-term courses of taking the drug heptral, hepa-merts, glycyrrhizic acid, phospholipids are prescribed.

The tactics of dealing with complications of cirrhosis is aimed at removing fluid from the abdominal cavity using diuretics, replacement therapy with albumin drugs in violation of the protein-synthetic function of the liver.With the development of signs of cholestasis (jaundice, pruritus), deoxycholic acid preparations are prescribed.

The prognosis of the course of the disease depends not only on doctors. Only a complete refusal to take alcohol allows us to hope for recovery from severe forms of alcoholic liver disease and alcoholic cirrhosis.

In our hepatology center, you can undergo examination and receive recommendations from a hepatologist.

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90,000 Alcohol h.2 – The secret of the gray nose – Dima Pechkin

“You cannot trust the opinion of a person who hasn’t had time to get drunk”
V. Erofeev, “Moscow – Petushki”

In the first part of this post I gave interesting statistical facts about drinking and non-drinking countries, in this I will touch a little on the sad consequences of excessive libation.

Scientists in Britain, a country with pronounced alcohol problems, have found that the longest alcohol hangover occurs at the age of 29 – it can last up to 10.5 hours.The increase in the duration of the hangover syndrome is associated with the “fatigue” of the body. At the age of 19-25, people feel great after drinking a lot of alcoholic beverages, but over time, the immune system weakens, and the body takes more time to process toxins.
In the course of the study, 65% of the respondents admitted that they had to go to work in a state of alcoholic intoxication. According to them, they felt worst of all at 10 am. Every tenth admitted that, under the influence of alcohol, he wrote various kinds of revelations in the social.networks, or called on a mobile phone, which he later regretted.

Most of us know firsthand what a hangover is. Throbbing headache, nausea, weakness, dry mouth, intense thirst, chills with a feeling of heat, possibly vomiting, dizziness, changes in blood pressure and heart failure are physically manifested symptoms. The mental background of the state of not getting drunk is a feeling of guilt and depressed mood, depression.
The hangover condition usually lasts no more than a day, but may last longer.How a hangover will manifest itself depends on the state of the body and its ability to break down alcohol. It is believed that a hangover occurs only after a serious amount of alcohol consumed. This is not true. For some people, in order to hate the morning, it is enough to drink a rather modest dose of alcohol in the evening. The smaller a person’s liver is, the more severely they suffer from a hangover. The normal female liver is smaller than the liver of men. Therefore, the breakdown of alcohol in women is slower and the suffering takes longer.

Actually, hangover torment is provided to us by three main factors. The first is the poisoning of the body, which occurs due to the breakdown of alcohol with the subsequent formation of poisons, which, in turn, cause the formation of new toxins. Vermouth, tequila, rum, whiskey start this process especially “effectively”. All the same British scientists recognized brandy as the most dangerous (no, not whiskey …). Low-alcohol drinks are most well excreted from the body, and of strong ones, vodka brings the least harm to the body, the hangover from it is lighter.

Disruption of the brain cells is the second factor that provides us with the mental consequences of yesterday’s fun. As a result of the breakdown of alcohol, acetaldehyde appears in the body, making the nervous system hypersensitive. Then even a dim light and quiet sounds greatly irritate a person. He may have an unreasonable sense of shame and guilt – “adrenaline anguish.”

The third factor is dehydration, which is not associated with a lack of water, but with its incorrect distribution in the body.Bags under the eyes are clear evidence of this. Remember the joke: “Where is the money? – In bags. Where are the bags? – Under the eyes.

Speaking of visual under the eyes: What is the secret of the characteristic blue nose of drunkards? Alcohol entering the bloodstream interacts with red blood cells, which are known to deliver oxygen to tissue cells and take carbon dioxide. In a normal state, red blood cells are covered with a thin fatty membrane and have a small electrical charge, due to which they repel each other and do not stick together.Alcohol dissolves the fatty membrane and removes the charge. As a result, red blood cells stick together in the so-called “grape bunches” of 5, 100 or even 1000 pieces, depending on the amount of alcohol consumed. “Bunches” clog up small vessels, which, dying off, acquire a purple color. With regular libations, not a single living capillary remains in the nose and the nose turns blue.

Unfortunately, in addition to the vessels in the nose, “grapes” also easily destroy the small vessels that supply the neurons in the human brain with blood.For each of the 15 billion neurons, we have only one vessel, without a spare. And only from 7 to 9 minutes a neuron lives after blockage of the feeding vessel. 1 liter of beer kills up to 6000 nerve cells, and 100 grams of vodka – 7000. A shriveled, ulcerated brain is the cause of the degradation of experienced alcoholics.

Hangovers are often mistakenly confused with withdrawal symptoms. The misconception is that withdrawal is not a direct consequence of the use of psychoactive substances, in particular alcohol, but, on the contrary, with a sharp refusal from them after long-term use.The well-known folk joke about O.R.Z. – “very sharply tied up”, succinctly describes the essence of abstinentia (abstinence), often accompanied by delirium, (delirium – madness, delirium) – “delirium tremens”.

Signs indicating the onset of delirium tremens are silent motor excitement with automatically repeated actions (often from professional activity), with mild hallucinations and delusions, as well as high body temperature. Delirium tremens is typical for visual hallucinations that are realistic, multiple, and mobile.As a rule, these are bedbugs, cockroaches, beetles, flies, less often – cats, rats, mice. Sometimes patients see large animals and people with a fantastic appearance. Characterized by visions of snakes, devils, as well as deceased relatives (the so-called “wandering dead”). Visual illusions and hallucinations can be both single and multiple and scene-like. Delirium tremens sometimes disappears within 3-5 days without treatment; less often it is delayed for 1-2 weeks. Convalescence is more likely to occur after deep, prolonged sleep.The condition may worsen in the evening and improve during the day.

Delirium usually occurs at stage III of alcoholism. But, do not be deluded by the distance of the sad prospect before assessing what stage you are already at.

The first stage of alcoholism is a pathological craving for alcoholic beverages. Loss of control over the amount drunk, intoxication often manifests itself in severe forms, accompanied by amnesia. Abstinence at this stage is not observed, and mental manifestations during this period are associated with low mood, irritability, high fatigue and low performance, signs of self-doubt.This stage of the disease can last 3–6 years.

At the second stage of alcoholism, alcohol dependence increases and withdrawal symptoms occur. This period is characterized by an uncontrolled and irrepressible craving for alcoholic beverages. The patient can be in continuous drunkenness for many days. The ability to work is further reduced, and fatigue increases. The character of a person also changes: rudeness, deceit, selfishness are manifested. Intellectual capacity, like memory, and the ability to make critical judgments, are greatly reduced.There is an imbalance in the emotional sphere – a tendency to hysteria, incontinence. Stage 2 can last 7–20 years.

The third stage of the disease is considered particularly severe. It is characterized by binge drinking lasting more than 1 week and interruptions followed by a period of binge drinking. Intoxication occurs very quickly, with small doses of alcohol. All the symptoms of the second stage intensify, the withdrawal syndrome becomes pronounced. On the physical plane, chronic gastritis, kidney and liver damage, hypertension and alcoholic cardiopathy are manifested.On the neurological level – vegetative dystonia, violation of tendon reflexes, polyneuritis. On the mental side – personality degradation. Increased excitability, a tendency to hypochondria take on the character of phobias.

With alcoholism in men, the cardiovascular system is more often affected, while women are more likely to suffer from disorders of the liver and gastrointestinal tract. Women susceptible to alcoholism begin to feel the hangover syndrome 3 years after the onset of the disease. At the same time, mental disorders prevail over somatic ones.There are rare cases in medical practice when the patient consumes fractional doses of alcohol, without taking breaks between binges. At the same time, withdrawal symptoms simply do not have time to develop.

Despite the obvious harmfulness of alcohol to human health, there is a constant debate about the dangers of small doses of alcohol. The opinion that in principle there are no harmless doses of alcohol is opposed to statements that drinking alcohol in moderation not only does not harm health, but also reduces the risk of premature death.
Once again, caring British: studies in which 14 thousand women took part showed that moderate drinkers are more likely to live to 70 years than non-drinkers or alcohol abusers. “Small doses of alcohol can really protect against heart disease, especially in post-menopausal women, but it’s important to be careful,” says Natasha Stewart of the British Heart Foundation.
There is also an opinion that regular alcohol consumption leads to the feminization of men and the masculinization of women, that is, in men, the mammary glands grow, the pelvis becomes wider and impotence develops, and women become more “masculine” – the voice, character, and facial hair appear.
Educational indicators are also very interesting – only 14% of convinced teetotalers have received higher education – and 37% of moderately drinking people.

Have you already determined the stage of alcoholism you are at? Is there something that worries or scares you in this regard? Or you can be sure that 200 gr. vodka or a bottle of wine after work only strengthens the work of your heart?

Watch the new video of my project “Magic Tablet” on Youtube!

🔽 Real psychotherapy in action! 🔽

THIOGAMMA tablets – instructions for use, price, dosages, analogs, contraindications

Clinical and pharmacological group

Metabolic drug

Active ingredient

– thioctic acid (thioctic40) Release form

and packaging

Film-coated tablets , oblong, biconvex, with a smooth and slightly shiny surface, with one dividing line on both sides, yellow with possible splashes of white and dark yellow.

	1 tab.
thioctic acid	600 mg

Excipients: hypromellose, colloidal silicon dioxide, microcrystalline cellulose (Ph212 type), lactose monohydrate, croscarmellose sodium, talc, dimethicone, magnesium stearate.

Composition of the film casing: macrogol 6000, hypromellose, talc, sodium lauryl sulfate.

10 pcs. – blisters (3) – cardboard packs.
10 Pcs. – blisters (6) – cardboard packs.
10 Pcs. – blisters (10) – cardboard packs.

Pharmacological action

Pharmacodynamics

Thioctic acid – endogenous antioxidant (binds free radicals).

Forms in the body during oxidative decarboxylation of alpha-keto acids.

As a coenzyme of mitochondrial multienzyme complexes, thioctic acid participates in the oxidative decarboxylation of pyruvic acid and alpha-keto acids.Thioctic acid helps to reduce the concentration of glucose in the blood and increase glycogen in the liver, as well as reduce insulin resistance.

Thioctic acid is involved in the regulation of lipid and carbohydrate metabolism, affects the metabolism of cholesterol, improves liver function, has a detoxifying effect in case of poisoning with salts of heavy metals and other intoxications. It has a hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effect. Improves the trophism of neurons.

In diabetes mellitus, thioctic acid reduces the formation of end products of glycation, improves endoneural blood flow, increases the content of glutathione to a physiological value, which as a result leads to an improvement in the functional state of peripheral nerve fibers in diabetic polyneuropathy.

Pharmacokinetics

Absorption and distribution

When taken orally, it is rapidly and completely absorbed in the gastrointestinal tract, simultaneous intake with food reduces absorption.Bioavailability – 30-60% due to the “first pass” effect through the liver. The time to reach C _max (4 μg / ml) is about 30 minutes.

V _d – 450 ml / kg.

Metabolism and excretion

Metabolized in the liver by side chain oxidation and conjugation.

80-90% of thioctic acid is excreted by the kidneys in the form of metabolites, in a small amount thioctic acid is excreted unchanged. T _1/2 – 25 min.The total plasma clearance is 10-15 ml / min.

Indications

Diabetic polyneuropathy;
alcoholic polyneuropathy.

Contraindications

hypersensitivity to thioctic acid or to any of the excipients;
age up to 18 years;
lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
pregnancy;
the period of breastfeeding.

Dosage

The drug is taken orally, on an empty stomach, 30 minutes before breakfast, without chewing and drinking a small amount of liquid.

Adults – 600 mg (1 tablet) 1 time / day.

In severe cases, treatment begins with the appointment of thioctic acid preparations in dosage forms for parenteral administration for 2-4 weeks, then the patient is transferred to treatment with oral forms of thioctic acid preparations.

The duration of the course and the need for its repetition are determined by the doctor.

For elderly patients , the usual dosing regimen is recommended.

For patients with impaired renal function , the usual dosing regimen is recommended.

For patients with moderate hepatic impairment , the usual dosing regimen is recommended. Clinical trial data and clinical experience with patients with severe hepatic impairment are not available. Safety and efficacy in patients with severe hepatic impairment has not been established.

The safety and efficacy of Thiogamma in children and adolescents aged 0 to 18 years have not yet been established. No data available.

Side effects

The frequency of adverse reactions listed below was determined as follows: very often (≥1 / 10), often (≥1 / 100 and <1/10), infrequently (≥1 / 1000 and <1 / 100), rarely (≥1 / 10000 and <1/1000), very rare (<1/10000, including isolated cases), the frequency is unknown (cannot be estimated from the available data).

From the digestive system: very rarely – nausea, vomiting, abdominal pain, diarrhea.

From the immune system: very rarely – allergic reactions (up to the development of anaphylactic shock), skin rash, urticaria, itching; autoimmune insulin syndrome (AIS), clinical manifestations of AIS can be: dizziness, sweating, muscle tremors, increased heart rate, nausea, headache, confusion, visual impairment, loss of consciousness, coma.

From the nervous system: very rarely – a change or violation of taste.

From the side of metabolism and nutrition: very rarely – due to improved absorption of glucose, a decrease in the concentration of glucose in the blood is possible. In this case, symptoms of hypoglycemia may occur – dizziness, increased sweating, headache, visual disturbances.

Skin and subcutaneous tissue disorders: frequency unknown – eczema.

If any of the above side effects are aggravated or any other side effects are noted, the patient should be informed of this by the doctor.

Reporting suspected adverse reactions

It is important to report suspected adverse reactions after registration of the medicinal product in order to ensure continuous monitoring of the benefit-risk ratio of the medicinal product. Healthcare professionals are encouraged to report any suspected adverse drug reactions through the national ADR reporting systems of the Eurasian Economic Union member states.

Overdose

Symptoms: nausea, vomiting, headache.

In the case of taking thioctic acid in doses from 10 to 40 g in combination with alcohol, cases of intoxication were observed, up to and including death.

Symptoms of acute overdose: psychomotor agitation or confusion, usually with the subsequent development of generalized seizures and the formation of lactic acidosis. Cases of hypoglycemia, shock, rhabdomyolysis, hemolysis, disseminated intravascular coagulation, bone marrow depression, and multi-organ failure have also been described.

Treatment: symptomatic. There is no specific antidote.

Drug interaction

Thioctic acid enhances the anti-inflammatory effect of GCS.

With the simultaneous appointment of thioctic acid and cisplatin, a decrease in the effectiveness of cisplatin is noted.

Thioctic acid binds metals, therefore it should not be administered simultaneously with drugs containing metals (for example, iron, magnesium, calcium preparations) – the interval between doses should be at least 2 hours.

With the simultaneous use of thioctic acid and insulin or oral hypoglycemic drugs, their effect may be enhanced.

Ethanol and its metabolites weaken the effect of thioctic acid.

Special instructions

Thiogamma preparation contains lactose (in the form of monohydrate). Patients with lactose intolerance, lactase deficiency, glucose-galactose malabsorption should not take this drug.

Patients with diabetes mellitus require constant monitoring of blood glucose concentration, especially at the initial stage of therapy.In some cases, it is necessary to reduce the dose of insulin or an oral hypoglycemic drug to avoid the development of hypoglycemia. With the development of hypoglycemia, you must immediately stop taking the drug Thiogamma.

If symptoms of hypersensitivity appear, you should immediately stop taking the drug Thiogamma.

Patients taking the drug Tiogamma should refrain from drinking alcohol, since alcohol consumption during therapy with Tiogamma reduces the therapeutic effect and is a risk factor contributing to the development and progression of neuropathy.

1 film-coated tablet of Tiogamma 600 mg contains less than 0.0041 bread units.

Cases of the development of autoimmune insulin syndrome (AIS) during treatment with thioctic acid have been described. The possibility of AIS appearance is determined by the presence of HLA-DRB1 * 04: 06 and HLA-DRB1 * 04: 03 alleles in patients.

When taking the drug, the use of dairy products is not recommended (due to the calcium content in them). The interval between taking thioctic acid and consuming dairy products should be at least 2 hours.

Simultaneous food intake can interfere with the absorption of thioctic acid.

Influence on the ability to drive vehicles and mechanisms

The effect of taking thioctic acid on the ability to drive vehicles and mechanisms has not been studied. Taking into account possible undesirable reactions (dizziness and the development of symptoms of hypoglycemia), care must be taken when driving vehicles and mechanisms, as well as when engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Pregnancy and lactation

Pregnancy

Clinical studies have not been conducted in pregnant women. The use of the drug Thiogamma during pregnancy is contraindicated.

Lactation period

Clinical studies have not been conducted in lactating women. The use of the drug Thiogamma during lactation is contraindicated.

Fertility

In preclinical studies in rats, oral thioctic acid had no effect on fertility.There are no clinical data on the effect of thioctic acid on fertility. Positive effects on semen analysis have been reported in infertile men with asthenoteratospermia. No negative fertility effects are expected for Thiogamma.

Use in children

The use of the drug under the age of 18 is contraindicated.

For impaired renal function

For patients with impaired renal function, the usual dosage regimen is recommended.

In case of impaired liver function

For patients with moderate impairment of liver function, the usual dosage regimen is recommended.

Safety and efficacy in patients with severe hepatic impairment has not been established.

Use in the elderly

For elderly patients, the usual dosage regimen is recommended.

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Overview

Symptoms

Diagnosis

Treatment

Alcohol-Induced Liver Disease | Cedars-Sinai

What is alcohol-induced liver disease?

What causes alcohol-induced liver disease?

What are the symptoms of alcohol-induced liver disease?

How is alcohol-induced liver disease diagnosed?

How is alcohol-induced liver disease treated?

What are possible complications of alcohol-induced liver disease?

Key points about alcohol-induced liver disease

Next steps

Alcoholics always know how to answer the question “why?”

Alcoholics make “stash”

Why can bleeding start after taking alcohol?

How to help with bleeding?

When can alcohol be consumed after bleeding has been corrected?

Nasal bleeding provocateurs

First aid measures

Providing care in a hospital setting

Why can bleeding start after taking alcohol?

How to help with bleeding?

When can I drink alcohol after eliminating bleeding?

Nose bleeding can be caused by a wide variety of causes.

Hangover or high blood pressure?

Why can blood pressure rise after drinking alcohol?

Hangover or high blood pressure?

Why can bleeding start after taking alcohol?

How to help with bleeding?

When can I drink alcohol after eliminating bleeding?

Why are high blood pressure dangerous after prolonged drunkenness?

After cleansing the body, pressure may jump. What is the reason for this?

Nose bleeding can be caused by a wide variety of causes.

Information

Transition of alcoholic liver disease to cirrhosis

What is the danger of cirrhosis in alcoholic liver disease?

Treatment of alcoholic cirrhosis

Can alcoholic cirrhosis of the liver be cured?

THIOGAMMA tablets – instructions for use, price, dosages, analogs, contraindications

Clinical and pharmacological group

Active ingredient

and packaging

Pharmacological action

Pharmacokinetics

Indications

Contraindications

Dosage

Side effects

Overdose

What are possible complications of alcohol-induced liver
disease?