Aspartate Aminotransferase (AST) Test (aka SGOT): High vs. Low Levels

Written by WebMD Editorial Contributors

• Why Would I Need This Test?
• How Do I Prepare?
• What Happens During the Test?
• What Are the Risks?
• What Do the Results Mean?
• Will I Take Other Tests?
• More

The aspartate aminotransferase (AST) test is a blood test that checks for liver damage. Your doctor might order this test to find out if you have liver disease and to monitor your treatment.

Your liver is an organ that has many important jobs.

It makes a fluid called bile that helps your body digest food. It also removes waste products and other toxins from your blood. It produces proteins, as well as substances that help your blood clot. Alcohol or drug use and diseases such as hepatitis can damage your liver and keep it from doing these jobs.

AST is an enzyme your liver makes. Other organs, like your heart, kidneys, brain, and muscles, also make smaller amounts. AST is also called SGOT (serum glutamic-oxaloacetic transaminase).

Normally, AST levels in your blood are low. When your liver is damaged, it puts more AST into your blood, and your levels rise.

A high AST level is a sign of liver damage, but it can also mean you have damage to another organ that makes it, like your heart or kidneys. That’s why doctors often do the AST test together with tests of other liver enzymes.

Your doctor can order an AST test if you have symptoms of liver damage, such as:

• Yellow skin or eyes, called jaundice
• Tiredness
• Weakness
• Swollen belly
• Stomach pain
• Appetite loss
• Itchy skin
• Dark-colored urine
• Light-colored poop
• Swelling in your legs and ankles
• Bruises

Other reasons to have this test:

• You’ve been exposed to the hepatitis virus.
• You drink a lot of alcohol.
• You take medicine that’s known to damage the liver.
• You have a family history of liver disease.
• You have obesity.
• You have diabetes or metabolic syndrome.
• You’ve had nonalcoholic fatty liver disease.

Your doctor might also want you to get this test to see if treatments you take for liver disease are working.

The AST test is also part of a comprehensive metabolic panel — a blood test your doctor does as part of a routine exam.

You don’t need any special preparation for the ALT test.

Tell your doctor what drugs or supplements you take. Some medicines can affect the results of this test.

A nurse or lab tech will take a sample of your blood — usually from a vein in your arm. They will first tie a band around the upper part of your arm to make your vein fill with blood and swell up. Then they will clean an area on your arm with an antiseptic and put a needle in one of your veins. Your blood will go into a vial or tube.

The blood test should only take a couple of minutes. After your blood is drawn, the lab tech will take off the band and pull out the needle. They’ll put a piece of gauze and a bandage where the needle went in to stop the bleeding.

The AST blood test is safe. Risks are usually minor, and can include:

• Bleeding
• Bruising
• Infection
• Pain when the needle is inserted
• Fainting or feeling dizzy

You should have the results in about a day. They are given in units per liter (units/L). Normal ranges are:

• Males: 10 to 40 units/L
• Females: 9 to 32 units/L

Your exact range may depend on which lab your doctor uses. Talk with them about the specifics of your case.

Higher-than-normal AST levels can be caused by:

• Chronic (ongoing) hepatitis
• Cirrhosis (long-term damage and scarring of the liver)
• Blockage in the bile ducts that carry digestive fluid from the liver to the gallbladder and intestine
• Liver cancer

Very high AST levels can be caused by:

• Acute viral hepatitis
• Damage to the liver from drugs or other toxic substances
• A blockage in blood flow to the liver

Your doctor might also compare your AST and ALT levels. If you have liver disease, usually your ALT level will be higher than your AST level.

These other conditions not tied to your liver can also raise your AST level:

• Burns
• Heart attack
• Intense exercise
• Muscle injury
• Pregnancy
• Pancreatitis
• Seizures
• Surgery

Some diseases or medicines you take can cause a “false positive” result on the AST test. This means your test is positive, even though you don’t have liver damage. Any of these can cause a false positive result:

• Diabetic ketoacidosis (Your body can’t make enough insulin, which helps sugar enter your cells.)
• Some antibiotics, such as erythromycin estolate or para-aminosalicylic acid (Paser)

AST is usually done as part of a group of liver function tests called a liver panel. It’s often ordered with a test for alanine aminotransferase (ALT), another liver enzyme.

ALT is more accurate than AST at detecting liver disease. It can more accurately show whether the problem is in your liver or in another part of your body, like your heart or muscles.

Your doctor can compare the amount of ALT to AST in your blood to find out whether you have liver damage or a problem with another organ, such as your heart.

Your doctor might also do other tests of enzymes and proteins your liver makes, such as:

• Alkaline phosphatase (ALP)
• Bilirubin
• Total protein

Talk with your doctor to make sure you understand all of your liver test results. Also find out how these results might affect your treatment.

Top Picks

Aspartate Aminotransferase (AST) Test (aka SGOT): High vs.

Low Levels

Written by WebMD Editorial Contributors

• Why Would I Need This Test?
• How Do I Prepare?
• What Happens During the Test?
• What Are the Risks?
• What Do the Results Mean?
• Will I Take Other Tests?
• More

The aspartate aminotransferase (AST) test is a blood test that checks for liver damage. Your doctor might order this test to find out if you have liver disease and to monitor your treatment.

Your liver is an organ that has many important jobs.

It makes a fluid called bile that helps your body digest food. It also removes waste products and other toxins from your blood. It produces proteins, as well as substances that help your blood clot. Alcohol or drug use and diseases such as hepatitis can damage your liver and keep it from doing these jobs.

AST is an enzyme your liver makes. Other organs, like your heart, kidneys, brain, and muscles, also make smaller amounts. AST is also called SGOT (serum glutamic-oxaloacetic transaminase).

Normally, AST levels in your blood are low. When your liver is damaged, it puts more AST into your blood, and your levels rise.

A high AST level is a sign of liver damage, but it can also mean you have damage to another organ that makes it, like your heart or kidneys. That’s why doctors often do the AST test together with tests of other liver enzymes.

Your doctor can order an AST test if you have symptoms of liver damage, such as:

• Yellow skin or eyes, called jaundice
• Tiredness
• Weakness
• Swollen belly
• Stomach pain
• Appetite loss
• Itchy skin
• Dark-colored urine
• Light-colored poop
• Swelling in your legs and ankles
• Bruises

Other reasons to have this test:

• You’ve been exposed to the hepatitis virus.
• You drink a lot of alcohol.
• You take medicine that’s known to damage the liver.
• You have a family history of liver disease.
• You have obesity.
• You have diabetes or metabolic syndrome.
• You’ve had nonalcoholic fatty liver disease.

Your doctor might also want you to get this test to see if treatments you take for liver disease are working.

The AST test is also part of a comprehensive metabolic panel — a blood test your doctor does as part of a routine exam.

You don’t need any special preparation for the ALT test.

Tell your doctor what drugs or supplements you take. Some medicines can affect the results of this test.

A nurse or lab tech will take a sample of your blood — usually from a vein in your arm. They will first tie a band around the upper part of your arm to make your vein fill with blood and swell up. Then they will clean an area on your arm with an antiseptic and put a needle in one of your veins. Your blood will go into a vial or tube.

The blood test should only take a couple of minutes. After your blood is drawn, the lab tech will take off the band and pull out the needle. They’ll put a piece of gauze and a bandage where the needle went in to stop the bleeding.

The AST blood test is safe. Risks are usually minor, and can include:

• Bleeding
• Bruising
• Infection
• Pain when the needle is inserted
• Fainting or feeling dizzy

You should have the results in about a day. They are given in units per liter (units/L). Normal ranges are:

• Males: 10 to 40 units/L
• Females: 9 to 32 units/L

Your exact range may depend on which lab your doctor uses. Talk with them about the specifics of your case.

Higher-than-normal AST levels can be caused by:

• Chronic (ongoing) hepatitis
• Cirrhosis (long-term damage and scarring of the liver)
• Blockage in the bile ducts that carry digestive fluid from the liver to the gallbladder and intestine
• Liver cancer

Very high AST levels can be caused by:

• Acute viral hepatitis
• Damage to the liver from drugs or other toxic substances
• A blockage in blood flow to the liver

Your doctor might also compare your AST and ALT levels. If you have liver disease, usually your ALT level will be higher than your AST level.

These other conditions not tied to your liver can also raise your AST level:

• Burns
• Heart attack
• Intense exercise
• Muscle injury
• Pregnancy
• Pancreatitis
• Seizures
• Surgery

Some diseases or medicines you take can cause a “false positive” result on the AST test. This means your test is positive, even though you don’t have liver damage. Any of these can cause a false positive result:

• Diabetic ketoacidosis (Your body can’t make enough insulin, which helps sugar enter your cells.)
• Some antibiotics, such as erythromycin estolate or para-aminosalicylic acid (Paser)

AST is usually done as part of a group of liver function tests called a liver panel. It’s often ordered with a test for alanine aminotransferase (ALT), another liver enzyme.

ALT is more accurate than AST at detecting liver disease. It can more accurately show whether the problem is in your liver or in another part of your body, like your heart or muscles.

Your doctor can compare the amount of ALT to AST in your blood to find out whether you have liver damage or a problem with another organ, such as your heart.

Your doctor might also do other tests of enzymes and proteins your liver makes, such as:

• Alkaline phosphatase (ALP)
• Bilirubin
• Total protein

Talk with your doctor to make sure you understand all of your liver test results. Also find out how these results might affect your treatment.

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AST (AST, aspartate aminotransferase): to be tested at “HEMOHELP”

Description
Preparation

What is AST (Aspartate aminotransferase, Aspartate aminotransferase)?

AST is an intracellular enzyme from the group of aminotransferases, catalyzing the reversible transfer of an amino group from aspartic acid (amino acid) to α-ketoglutaric acid (keto acid) with the formation of oxalacetate. The highest concentration of this enzyme is observed in the myocardium (heart muscle), liver, skeletal muscles, kidneys, at a lower concentration of AST is found in the pancreas, spleen, lungs and erythrocytes. In the myocardium, the activity of AST is 10,000 times higher than in blood serum, and in erythrocytes, AST is 10 times higher than in serum. Enzyme activity in women is slightly lower than in men. The activity of AST in the blood serum increases in a number of diseases, especially when organs and tissues rich in this enzyme are affected. An increase in plasma AST activity indicates cell damage rather than organ dysfunction. The most dramatic changes in AST activity are observed when the heart muscle is damaged. In myocardial infarction, serum AST activity can increase 2-20 times, and increased activity can be detected even before the appearance of typical signs of a heart attack on the ECG. There is a relationship between the size of the focus of necrosis in the heart muscle and the level of AST in the blood serum. The prognostic value of determining the activity of AST is also important: if on the 3rd-4th day of the disease the activity of this enzyme does not decrease, then the prognosis is poor. An increase in activity may indicate both the expansion of the infarction focus and the involvement of other organs and tissues in the process, such as the liver. In angina pectoris, AST activity, as a rule, remains within the normal range. Although in severe coronary insufficiency, in the first 24 hours, AST activity increases and normalizes 2-3 days after the attack. AST also rises in acute hepatitis and other severe lesions of hepatocytes (liver cells). Simultaneous determination of the activity of two aminotransferases (AlAT and AST) is a valuable diagnostic test. Normally, the ratio of AST/ALAT activities (de Ritis coefficient) is 1.33±0.42. In diseases of the liver, this ratio decreases, and in diseases of the heart, it rises sharply.

Indications for analysis:

• diagnosis and differential diagnosis of myocardial infarction and other diseases of the heart muscle;
• liver disease;
• skeletal muscle pathology.

When can there be an increase in the activity of AST in the blood serum?

• Myocardial infarction.
• Acute rheumatic heart disease.
• Cardiac intervention.
• Angiocardiography (catheterization of the heart vessels).
• Thrombosis of the pulmonary artery.
• Severe attack of angina pectoris, tachyarrhythmia.
• Viral hepatitis.
• Toxic liver damage (carbon tetrachloride, chloroform, pesticides).
• Cirrhosis of the liver.
• Cholestasis (blockage of the bile ducts).
• amoeboid infections.
• Cholangitis.
• Infectious mononucleosis.
• Acute alcohol poisoning.
• hemolytic syndrome.
• Skeletal muscle injury.
• Muscular dystrophies.
• Acute pancreatitis (inflammation of the pancreas).

When can there be a decrease in the activity of AST in the blood serum?

• Severe necrotic processes, liver rupture (an unfavorable prognostic sign is a sharp decrease in the activity of AST and ALT against the background of stable or progressive hyperbilirubinemia – an increase in bilirubin).
• Vitamin B6 deficiency.

Strictly on an empty stomach – you must refrain from eating for 8-12 hours.

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Norm of ALT and AST levels in a blood test in women: what do you need to know?

Contents

• 1 ALT and AST norms in women’s blood tests
  • 1.1 Women’s blood tests
  • 1.2 What are ALT and AST?
  • 1.3 The value of ALT and AST in the blood test
  • 1.4 Normal levels of ALT and AST in women
  • 1.5 The effect of age on the level of ALT and AST
  • 1.6 Causes of elevated levels of ALT and AST
  • 1.7 Liver disease and ALT and AST levels
  • 1.8 Cardiovascular disease and ALT and AST levels
  • 1.9 Causes of low ALT and AST levels
  • 1.10 Related videos:
  • 1.11 Q&A:
    • • 1.11.0.1 What are ALT and AST?
      • 1. 11.0.2 Why measure ALT and AST blood levels?
      • 1.11.0.3 What are the ALT and AST norms for women?
  • 1.12 Liver disease and low levels of ALT and AST
  • 1.13 Vitamin deficiency and low levels of ALT and AST

Normal levels of ALT (alanine aminotransferase) and AST (aspartate aminotransferase) in a blood test in women. What values ​​are considered normal and what may indicate deviations from the norm. Important indicators for diagnosing the condition of the liver and heart.

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are enzymes that are found inside liver and heart cells. They play an important role in the metabolism of amino acids and are involved in the process of energy formation. The study of the levels of ALT and AST in the blood test reveals the presence and extent of damage to these organs.

Normal values ​​of ALT and AST are somewhat different in men and women, due to differences in body physiology. On average, in women, the acceptable level of ALT is from 7 to 35 units per liter, and the level of AST is from 7 to 31 units per liter of blood.

Elevated levels of ALT and AST may be indicative of various diseases and conditions. For example, elevated ALT levels may be associated with liver disease such as hepatitis or cirrhosis, and AST levels may be elevated with myocardial infarction or heart failure. However, elevated values ​​of these enzymes can also indicate other problems in the body, so diagnosis always requires an integrated approach and additional research.

Blood test for women

Blood test is one of the most common and informative laboratory procedures for assessing the health of women. It allows you to identify various deviations and pathologies, as well as monitor the effectiveness of treatment.

One of the key indicators in the blood test are the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). These enzymes are found in the cells of the liver and heart, respectively, and an increase in them may indicate problems with these organs.

Normal blood levels of ALT and AST in women depend on age and health status. Typically, ALT levels do not exceed 31 U/L and AST levels do not exceed 35 U/L. However, it must be taken into account that these indicators may vary depending on the laboratory and the research method.

Elevated ALT and AST levels in a woman’s blood test can be due to various causes, including liver disease (hepatitis, cirrhosis), heart disease (heart attack, angina pectoris), as well as the use of certain drugs or an alcohol disorder.

For women, regular blood testing is an important tool for maintaining health and preventing serious illness. In case of detection of deviations in the levels of ALT and AST, it is necessary to consult a doctor for additional studies and diagnosis.

What are ALT and AST?

ALT and AST are shorthand for enzymes called alanine aminotransferase (ALT) and aspartate aminotransferase (AST). They are present inside the cells of organs, especially in the liver, heart, muscles and kidneys. Blood levels of ALT and AST can be used to assess the function of these organs.

ALT and AST are enzymes that play a key role in amino acid metabolism in the body. ALT is responsible for the transfer of the amino group from alanine to alpha-ketoglutarate, and AST from aspartate to alpha-ketoglutarate. These enzymes are an integral part of the process of amino acid metabolism and energy metabolism in the body.

ALT and AST are located inside the cells of organs and usually they practically do not penetrate into the blood. However, when cells are damaged, the levels of these enzymes can increase and enter the bloodstream. Elevated ALT levels may indicate liver damage, while elevated AST levels may indicate damage to the liver, heart, or muscles.

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ALT and AST blood count

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are enzymes that are found inside the cells of organs, especially the liver and heart. When cell integrity is compromised, these enzymes are released into the blood.

ALT and AST can be used to determine the presence or extent of organ damage. Usually, their levels are markedly increased in the presence of liver diseases such as hepatitis or cirrhosis, as well as in heart disease and muscle damage.

ALT and AST values ​​in a blood test can be expressed in different units, but they are usually expressed in units per liter (U/L) or international activity units (IU/L). Normal ALT and AST values ​​depend on the laboratory performing the analysis and may differ in different countries and medical institutions.

In general, normal levels of ALT and AST in a blood test for women may be as follows:

• ALT: 7-35 U/L
• AST: 10-30 U/L

However, it is important to note that normal values ​​may differ slightly depending on the technique used in the laboratory, so the doctor’s advice should be taken into account when interpreting the results.

If the levels of ALT and AST in the blood test exceed the norm, this may indicate the presence of a pathological process in the liver, heart or other organs. In this case, the doctor may prescribe additional studies to determine the cause of the increase in these enzymes.

Normal levels of ALT and AST in women

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are enzymes that are found inside the cells of various organs, including the liver, heart, muscles, kidneys and others. The level of these enzymes in the blood can indicate the condition of these organs.

Normal ALT levels in women vary by analysis and lab, but typically range from 7 to 35 units per litre. Elevated ALT levels can indicate various liver problems such as hepatitis, cirrhosis, or other diseases.

Normal AST levels in women can also vary depending on the analysis, but are usually between 5 and 40 units per liter. Elevated AST levels can indicate a variety of problems, including heart and muscle disease, and liver or kidney damage.

If ALT and AST levels in a woman’s blood are higher than normal, it is recommended to see a doctor for an examination and find out the cause. Diagnosis of the underlying disease that caused the increase in ALT and AST levels will allow prescribing effective treatment and preventing possible complications.

Effect of age on ALT and AST levels

Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) blood levels in women may vary with age. With age, there is often a gradual increase in the levels of these enzymes.

ALT and AST levels may increase in women over 40 due to age-related changes in the body. This is due to the deterioration of metabolic processes, changes in the functional activity of the liver and muscles.

ALT and AST levels can also be affected by age due to various diseases that can occur with age. Some diseases, such as cirrhosis of the liver, hepatitis, cholecystitis and other pathologies of the biliary tract, can lead to an increase in the level of ALT and AST.

It should be noted that the level of ALT and AST may vary depending on the individual characteristics of the woman. Therefore, when analyzing blood, it is necessary to take into account age, general condition of the body and other factors that can affect the level of these enzymes.

Causes of elevated levels of ALT and AST

Elevated levels of ALT and AST in the blood test in women can be caused by various reasons. This may be due to damage to cells in the liver, heart, muscles, or other organs.

One of the most common causes of elevated ALT and AST levels is liver disease such as cirrhosis or hepatitis. In these diseases, liver cells are damaged and the level of ALT and AST in the blood increases significantly.

Also elevated levels of ALT and AST can be caused by heart problems such as myocardial infarction or heart failure. When the heart muscle is damaged, more ALT and AST are released, which leads to their increase in the blood.

Other causes of elevated ALT and AST levels include the use of certain drugs, alcohol or drug poisoning, mechanical damage to organs or muscles, infectious diseases, and certain genetic disorders.

It is important to note that elevated ALT and AST levels do not always indicate a serious problem and may be temporary or caused by minor causes. However, if elevated levels of ALT and AST persist, it is necessary to consult a doctor for further examination and clarification of the cause.

Liver disease and ALT and AST levels

Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are enzymes that are found in high concentrations in liver cells. With the development of various liver diseases, such as hepatitis, cirrhosis, fatty degeneration, and others, the levels of ALT and AST can increase significantly.

However, an increase in ALT and AST may not always indicate the presence of a disease. The levels of these enzymes can also be elevated in the event of injury, certain medications, strenuous exercise, and even after drinking alcohol.

To determine the state of the liver and diagnose possible diseases, in addition to ALT and AST levels, a comprehensive blood test is usually performed, including the assessment of other indicators, such as levels of bilirubin, gamma-glutamyl transferase (GGT), alkaline phosphatase, and the diagnostic role of which is also very important.

When ALT and AST levels are abnormal, your doctor may recommend additional tests such as liver ultrasound, Liverscan, liver biopsy, and others. It is important to remember that it is impossible to draw final conclusions about the state of the liver only by the levels of ALT and AST, a comprehensive assessment of all indicators and a medical opinion are required.

Therefore, if you have elevated levels of ALT and AST, do not panic, see a doctor who can diagnose and identify the cause of such changes. Medical care and timely access to a doctor play an important role in assessing the condition of the liver and preventing possible complications.

Cardiovascular disease and ALT and AST levels

Cardiovascular disease is one of the leading causes of death among women worldwide. Often these diseases do not have pronounced symptoms in the early stages, so it is important to regularly monitor your health and conduct tests, including ALT and AST levels.

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are enzymes found in various organs, including the liver and heart. If these organs are damaged, the levels of ALT and AST can increase significantly, indicating the presence of pathological processes.

The level of ALT in a blood test is an indicator of liver function. With defects and damage to the liver cells, such as cirrhosis or hepatitis, ALT may increase. In addition, elevated ALT levels may indicate the presence of heart failure, which often develops against the background of cardiovascular disease.

At the same time, AST levels can also be an indicator of heart disease. An increase in AST may indicate the presence of myocardial infarction or acute coronary syndrome. However, a simple increase in the level of AST is not a specific indicator of cardiovascular disease, so additional examination is required to clarify the diagnosis.

Thus, the control of ALT and AST levels in the blood test is an important step in the diagnosis of cardiovascular diseases in women. Elevated values ​​of these enzymes may indicate the presence of a pathology, however, an integrated approach and additional examination are required to make an accurate diagnosis and prescribe treatment.

Causes of low levels of ALT and AST

Low levels of ALT (alanine aminotransferase) and AST (aspartate aminotransferase) in the blood test can indicate various diseases and conditions in the body of women.

1. Liver failure: Low levels of ALT and AST may indicate serious problems with the liver. This may be due to cirrhosis of the liver, chronic hepatitis, hepatic necrosis, or other liver pathologies.

2. Heart disease: Low AST levels may be associated with heart disease such as myocardial infarction, heart failure, or arrhythmia. This is due to the fact that AST is contained in the mitochondria of the heart muscle and its decrease may indicate damage to the heart tissue.

3. Vitamin deficiencies: Low levels of ALT and AST may be due to a lack of important vitamins such as vitamin B6 and vitamin B12. Deficiency of these vitamins can cause abnormalities in the functioning of the liver and heart, which leads to a decrease in the levels of ALT and AST in the blood.

4. Individual features: Some women have low levels of ALT and AST in the blood up to the physiological norm. This may be due to the peculiarities of their metabolism or genetic factors. In such cases, low levels of ALT and AST are usually not dangerous and do not require additional examination or treatment.

It is important to note that low levels of ALT and AST in the blood test require further investigation and consultation with a physician. Only he can determine the specific cause of such changes and prescribe the necessary treatment or observation.

Related videos:

Q&A:

What are ALT and AST?

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are enzymes found in the cells of the liver, heart, muscles and other organs. They specifically process certain amino acids and help in converting them into energy for the body to work.

Why should ALT and AST levels be measured?

Blood levels of ALT and AST can be used to assess the condition of the liver and other organs such as the heart and muscles. Elevated levels of these enzymes may indicate the presence of inflammation or damage to the cells in these organs.

What are the ALT and AST norms for women?

Normal blood levels of ALT and AST may vary slightly between laboratories depending on the methods used. In general, normal ALT levels usually do not exceed 30 U/L and AST levels do not exceed 34 U/L. However, for an accurate interpretation of the results, it is best to consult a doctor who knows the patient’s history and can take into account other factors.

Liver disease and low ALT and AST levels

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) blood values ​​are important indicators of liver function. They help determine the presence or absence of damage to the organ. In some liver diseases, however, ALT and AST levels may be low or normal, which can be difficult to diagnose.

One cause of low ALT and AST may be liver atrophy. With this disease, the volume of the liver decreases, which leads to a decrease in the activity of enzymes. Another possible cause of low levels of ALT and AST is cirrhosis of the liver, which is characterized by the replacement of healthy organ tissue with scarring. In this case, the number of liver cells that produce ALT and AST decreases, which leads to low levels of these enzymes in the blood.

In addition to atrophy and cirrhosis of the liver, low levels of ALT and AST may be associated with the presence of diseases for the first time that can suppress the functioning of the organ. These diseases include hepatitis and fatty degeneration of the liver. In these pathologies, inflammation and accumulation of lipids in the liver are present, which leads to a decrease in the activity of ALT and AST. This, in turn, may indicate the presence of a progression of the disease or a reactive state of the body.

It is important to note that low levels of ALT and AST are not specific signs of specific liver diseases and may be symptoms of various pathologies. Additional studies and analyzes are needed for an accurate diagnosis. Blood test results should be interpreted in the light of other clinical findings and in consultation with the physician.

Vitamin deficiencies and low levels of ALT and AST

A significant decrease in ALT and AST levels in the blood test in women may be associated with a vitamin deficiency. Vitamins are important trace elements necessary for the normal functioning of the body. They are catalysts for many biochemical reactions, including those that regulate ALT and AST levels.

Deficiency of certain vitamins can lead to decreased activity of these enzymes. For example, a lack of vitamin B6 may be associated with low levels of ALT and AST.