How does atorvastatin work to lower cholesterol levels. What are the common side effects of atorvastatin. How should atorvastatin be taken for maximum effectiveness. What precautions should be considered when using atorvastatin. How does atorvastatin interact with other medications and substances.

Understanding Atorvastatin: A Powerful Cholesterol-Lowering Medication

Atorvastatin is a widely prescribed medication belonging to the statin class of drugs. Its primary function is to help lower “bad” cholesterol and fats in the blood while simultaneously raising “good” cholesterol levels. This dual action makes it an essential tool in the fight against cardiovascular diseases.

Atorvastatin works by inhibiting an enzyme called HMG-CoA reductase, which plays a crucial role in cholesterol production in the liver. By reducing the amount of cholesterol produced, atorvastatin helps maintain healthy cholesterol levels in the bloodstream.

Key Benefits of Atorvastatin

• Lowers LDL (low-density lipoprotein) cholesterol
• Reduces triglyceride levels
• Increases HDL (high-density lipoprotein) cholesterol
• Decreases the risk of heart disease
• Helps prevent strokes and heart attacks

Is atorvastatin effective for everyone? While atorvastatin is generally effective for most people, individual responses may vary. Factors such as genetics, lifestyle, and overall health can influence the medication’s efficacy. Regular check-ups and blood tests are essential to monitor its effectiveness and adjust the dosage if necessary.

Proper Administration of Atorvastatin for Maximum Effectiveness

To achieve optimal results with atorvastatin, it’s crucial to follow the prescribed dosage and administration guidelines. The medication is typically taken once daily, preferably at the same time each day to maintain consistent blood levels.

Administration Guidelines

1. Take atorvastatin on an empty stomach, either 1 hour before or 2 hours after a meal.
2. If using the oral suspension, shake the bottle well before each dose.
3. Use a special measuring device or spoon to ensure accurate dosing.
4. Avoid grapefruit or grapefruit juice while taking atorvastatin, unless approved by your healthcare provider.
5. If also taking bile acid-binding resins, take atorvastatin at least 1 hour before or 4 hours after these medications.

Can atorvastatin be taken with food? While it’s generally recommended to take atorvastatin on an empty stomach, some people may experience digestive discomfort. In such cases, taking it with a small, low-fat snack may be acceptable. However, always consult your healthcare provider before making any changes to your medication regimen.

Potential Side Effects and Monitoring Strategies

Like all medications, atorvastatin can cause side effects, although not everyone experiences them. It’s essential to be aware of potential adverse reactions and report any concerns to your healthcare provider promptly.

Common Side Effects

• Muscle pain or weakness
• Headache
• Digestive issues (nausea, diarrhea, constipation)
• Mild memory problems or confusion (rare)
• Elevated blood sugar levels

Are there any serious side effects to watch out for? While rare, some people may experience more severe side effects such as liver problems, muscle damage (rhabdomyolysis), or allergic reactions. Symptoms to monitor include persistent muscle pain, weakness, fever, dark urine, yellowing of the skin or eyes, and severe abdominal pain. If any of these occur, seek medical attention immediately.

Lifestyle Modifications to Enhance Atorvastatin’s Effectiveness

While atorvastatin is a powerful tool in managing cholesterol levels, combining it with a healthy lifestyle can significantly enhance its effectiveness. By adopting certain lifestyle modifications, patients can maximize the benefits of their medication and improve their overall cardiovascular health.

Key Lifestyle Changes

• Follow a heart-healthy diet low in saturated and trans fats
• Engage in regular physical activity (at least 150 minutes of moderate-intensity exercise per week)
• Maintain a healthy weight or lose weight if overweight
• Quit smoking and limit alcohol consumption
• Manage stress through relaxation techniques or mindfulness practices

How does exercise complement atorvastatin treatment? Regular physical activity helps boost HDL cholesterol levels, improves insulin sensitivity, and promotes overall cardiovascular health. When combined with atorvastatin, exercise can lead to more significant improvements in lipid profiles and reduce the risk of heart disease more effectively than medication alone.

Interactions and Precautions: Ensuring Safe Use of Atorvastatin

Understanding potential drug interactions and taking necessary precautions is crucial for the safe and effective use of atorvastatin. Certain medications, supplements, and medical conditions can affect how atorvastatin works in the body or increase the risk of side effects.

Important Interactions to Consider

• Other cholesterol-lowering medications (e.g., fibrates, niacin)
• Certain antibiotics and antifungal medications
• HIV protease inhibitors
• Cyclosporine
• Warfarin and other blood thinners

Do herbal supplements interact with atorvastatin? Some herbal supplements, such as St. John’s Wort, may interact with atorvastatin and affect its efficacy. Always inform your healthcare provider about any supplements or over-the-counter medications you’re taking to avoid potential interactions.

Medical Conditions Requiring Special Attention

Certain medical conditions may require dosage adjustments or closer monitoring when taking atorvastatin. These include:

• Liver disease or history of liver problems
• Kidney disease
• Diabetes or pre-diabetes
• Thyroid disorders
• History of muscle problems or rhabdomyolysis

Is it safe to take atorvastatin during pregnancy or while breastfeeding? Atorvastatin is generally not recommended during pregnancy or while breastfeeding due to potential risks to the developing fetus or infant. If you become pregnant while taking atorvastatin, inform your healthcare provider immediately to discuss alternative treatment options.

Long-Term Benefits and Cardiovascular Risk Reduction

The long-term use of atorvastatin has been associated with significant reductions in cardiovascular events and mortality rates. By consistently lowering LDL cholesterol levels and improving overall lipid profiles, atorvastatin plays a crucial role in preventing heart attacks, strokes, and other cardiovascular complications.

Key Long-Term Benefits

• Reduced risk of major cardiovascular events
• Slowed progression of atherosclerosis
• Improved overall cardiovascular health
• Potential reduction in the need for invasive procedures (e.g., angioplasty, bypass surgery)
• Enhanced quality of life and longevity

How long does it take to see the full benefits of atorvastatin? While some improvements in cholesterol levels may be observed within a few weeks of starting treatment, the full cardiovascular benefits of atorvastatin typically become apparent after several months to years of consistent use. Regular follow-ups and lipid profile checks are essential to monitor progress and ensure ongoing effectiveness.

Managing Atorvastatin Treatment: Tips for Patients and Caregivers

Effectively managing atorvastatin treatment requires active participation from patients and their caregivers. By following these tips and strategies, individuals can optimize their treatment outcomes and minimize potential complications.

Practical Tips for Atorvastatin Management

1. Set up a medication reminder system to ensure consistent daily dosing
2. Keep a record of any side effects or concerns to discuss with your healthcare provider
3. Schedule regular check-ups and lipid profile tests as recommended
4. Maintain open communication with your healthcare team about any changes in your health or medication regimen
5. Stay informed about the latest research and guidelines regarding statin therapy

What should patients do if they miss a dose of atorvastatin? If a dose is missed, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Never take a double dose to make up for a missed one.

Addressing Common Concerns and Misconceptions

Many patients have concerns or misconceptions about statin therapy that may affect their adherence to treatment. Addressing these issues can help improve patient compliance and outcomes:

• Fear of side effects: Educate patients on the rarity of severe side effects and the importance of reporting any concerns promptly
• Belief that statins are only for older adults: Explain that statins can benefit individuals of various ages with elevated cardiovascular risk
• Misconception that statins replace the need for a healthy lifestyle: Emphasize the importance of combining medication with diet and exercise
• Concerns about long-term use: Discuss the proven long-term safety profile of statins and the benefits of consistent use

By addressing these concerns and providing accurate information, healthcare providers can help patients make informed decisions about their atorvastatin treatment and maximize its benefits.

Future Directions in Statin Therapy and Cholesterol Management

As research in cardiovascular medicine continues to advance, new developments in statin therapy and cholesterol management are emerging. These innovations may shape the future of atorvastatin use and provide additional options for patients with high cholesterol or cardiovascular risk.

Emerging Trends and Research Areas

• Personalized medicine approaches to statin therapy based on genetic profiles
• Combination therapies pairing statins with newer cholesterol-lowering medications
• Extended-release formulations for improved adherence and efficacy
• Investigation of statins’ potential benefits in other medical conditions (e.g., certain cancers, neurodegenerative diseases)
• Development of alternative cholesterol-lowering strategies for statin-intolerant patients

How might future developments impact atorvastatin treatment? As research progresses, we may see more tailored approaches to statin therapy, with dosing and treatment plans optimized based on individual patient characteristics. Additionally, new combination therapies may enhance the effectiveness of atorvastatin in managing complex lipid disorders and reducing cardiovascular risk.

The Role of Technology in Cholesterol Management

Technological advancements are also playing an increasingly important role in cholesterol management and statin therapy:

• Mobile apps for medication reminders and tracking of cholesterol levels
• Wearable devices that monitor cardiovascular health markers
• Telemedicine platforms for remote consultations and follow-ups
• Artificial intelligence algorithms to predict treatment responses and optimize dosing

These technological tools have the potential to improve patient adherence, enhance monitoring of treatment effectiveness, and facilitate more personalized approaches to cholesterol management.

As we look to the future, the landscape of statin therapy and cholesterol management continues to evolve. While atorvastatin remains a cornerstone of treatment for many patients, ongoing research and technological advancements promise to further refine and enhance our approach to cardiovascular risk reduction. Patients and healthcare providers alike should stay informed about these developments to ensure optimal treatment outcomes and improved cardiovascular health.

Atorvastatin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Atorvastatin is used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. It belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver. Lowering “bad” cholesterol and triglycerides and raising “good” cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

How to use Atorvastatin 20 Mg/5 Ml (4 Mg/Ml) Oral Suspension

Read the Patient Information Leaflet if available from your pharmacist before you start taking atorvastatin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily. It should be taken on an empty stomach, 1 hour before or 2 hours after a meal.

The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

If you also take certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take atorvastatin at least 1 hour before or at least 4 hours after taking these medications. These products can react with atorvastatin, preventing its full absorption.

Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. Keep taking this medication even if you feel well. Most people with high cholesterol or triglycerides do not feel sick.

It is very important to continue to follow your doctor’s advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of this drug.

Side Effects

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very small number of people taking atorvastatin may have mild memory problems or confusion. If these rare effects occur, talk to your doctor.

Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks.

This drug may rarely cause muscle problems (which can rarely lead to very serious conditions called rhabdomyolysis and autoimmune myopathy). Tell your doctor right away if you develop any of these symptoms during treatment and if these symptoms last after your doctor stops this drug: muscle pain/tenderness/weakness (especially with fever or unusual tiredness), signs of kidney problems (such as change in the amount of urine).

This medication may rarely cause liver problems. Tell your doctor right away if you develop symptoms of liver problems, including: nausea/vomiting that doesn’t stop, yellowing eyes/skin, dark urine, stomach/abdominal pain.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking atorvastatin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, alcohol use.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Limit alcoholic beverages. Daily use of alcohol may increase your risk for liver problems, especially when combined with atorvastatin. Ask your doctor or pharmacist for more information.

Older adults may be more sensitive to the side effects of this drug, especially muscle problems.

During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: daptomycin, gemfibrozil.

Other medications can affect the removal of atorvastatin from your body, which may affect how atorvastatin works. Examples include glecaprevir plus pibrentasvir, telithromycin, ritonavir, among others.

Do not take any red yeast rice products while you are taking atorvastatin because some red yeast rice products may also contain a statin called lovastatin. Taking atorvastatin and red yeast rice products together can increase your risk of serious muscle and liver problems.

Does Atorvastatin 20 Mg/5 Ml (4 Mg/Ml) Oral Suspension interact with other drugs you are taking?

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Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others.

Lab and/or medical tests (such as blood cholesterol/triglyceride levels, liver function) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember unless it is more than 12 hours after the time you usually take the dose. In that case, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Store the suspension form in the original container. Discard the suspension form 60 days after opening the bottle, even if there is medication left. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Atorvastatin: MedlinePlus Drug Information

pronounced as (a tore’ va sta tin)

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[Posted 07/20/2021]

AUDIENCE: Patient, Health Professional, OBGYN, Cardiology, Endocrinology, Pharmacy

ISSUE: The FDA is requesting revisions to the information about use in pregnancy in the prescribing information of the entire class of statin medicines. These changes include removing the contraindication against using these medicines in all pregnant patients. A contraindication is FDA’s strongest warning and is only added when a medicine should not be used because the risk clearly outweighs any possible benefit. Because the benefits of statins may include prevention of serious or potentially fatal events in a small group of very high-risk pregnant patients, contraindicating these drugs in all pregnant women is not appropriate.

FDA expects removing the contraindication will enable health care professionals and patients to make individual decisions about benefit and risk, especially for those at very high risk of heart attack or stroke. This includes patients with homozygous familial hypercholesterolemia and those who have previously had a heart attack or stroke.

BACKGROUND: Statins are a class of prescription medicines that have been used for decades to lower low-density lipoprotein (LDL-C or “bad”) cholesterol in the blood. Medicines in the statin class include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin.

RECOMMENDATIONS:

• Patients: Patients taking statins should notify their health care professionals if they become pregnant or suspect they are pregnant. Your health care professional will be able to advise whether you should stop taking the medicine during pregnancy and whether you may stop your statin temporarily while breastfeeding. Patients who are at high risk of heart attack or stroke who require statins after giving birth should not breastfeed and should use alternatives such as infant formula.
• Health Care Professionals: Health care professionals should discontinue statin therapy in most pregnant patients, or they can consider the ongoing therapeutic needs of the individual patient, particularly those at very high risk for cardiovascular events during pregnancy. Because of the chronic nature of cardiovascular disease, treatment of hyperlipidemia is not generally necessary during pregnancy. Discuss with patients whether they may discontinue statins temporarily while breastfeeding. Advise those who require a statin because of their cardiovascular risk that breastfeeding is not recommended because the medicine may pass into breast milk

The FDA hopes the revised language in the prescribing information will help reassure health care professionals that statins are safe to prescribe in patients who can become pregnant, and help them reassure patients with unintended statin exposure in early pregnancy or before pregnancy is recognized that the medicine is unlikely to harm the unborn baby.

For more information visit the FDA website at: http://www.fda.gov/Safety/MedWatch/SafetyInformation and http://www.fda.gov/Drugs/DrugSafety.

Atorvastatin is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Atorvastatin is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol (‘bad cholesterol’) and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol (‘good cholesterol’) in the blood. Atorvastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Atorvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with atorvastatin has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks.

Atorvastatin comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take atorvastatin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take atorvastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of atorvastatin and gradually increase your dose, not more than once every 2 to 4 weeks.

Continue to take atorvastatin even if you feel well. Do not stop taking atorvastatin without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking atorvastatin,

Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Avoid drinking large amounts [more than 1.2 liter (approximately 1 quart) per day] of grapefruit juice while taking atorvastatin.

Take the missed dose as soon as you remember it. However, if it is less than 12 hours until your next scheduled dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Atorvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• diarrhea
• heartburn
• gas
• joint pain
• forgetfulness or memory loss
• confusion

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor or get emergency medical help immediately:

• muscle pain, tenderness, or weakness
• lack of energy
• fever
• chest pain
• nausea
• extreme tiredness
• weakness
• unusual bleeding or bruising
• loss of appetite
• pain in the upper right part of the stomach
• flu-like symptoms
• dark colored urine
• yellowing of the skin or eyes
• rash
• hives
• itching
• difficulty breathing or swallowing
• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• hoarseness

Atorvastatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.

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• Caduet^® (containing Amlodipine, Atorvastatin)
• Liptruzet^® (containing Atorvastatin, Ezetimibe)

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What helps, side effects, composition

THERE ARE CONTRAINDICATIONS. POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS REQUIRED. For the heart and blood vesselsCholesterol

The author of the article

Sumenkova Anna Mikhailovna, pharmacist

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The content of the article

• Atorva statin: composition
• Atorvastatin: before or after meals
• Atorvastatin: side effects
• Rosuvastatin or Atorvastatin: which is better
• Liprimar or Atorvastatin: which is better
• Atorvastatin or Atoris: which is better
• Summary
• Ask an expert on the topic of the article vascular diseases . Few people know that one of the main factors in the development of heart and vascular diseases is an increase in the level of cholesterol in the blood. To avoid the risk of violations, a special group of drugs is used – statins. One of these drugs will be discussed in the article.

  Anna Sumenkova, a pharmacist, will talk about Atorvastatin: introduce its composition, rules of administration, side effects, and compare it with analogues.

  Atorvastatin: Composition

  Atorvastatin tablets based on the active ingredient of the same name in dosages of 10 mg, 20 mg, 40 mg and 80 mg. The drug is produced by many manufacturers, as well as as part of complex preparations, so it is impossible to derive a single composition of auxiliary agents. The drug can be found under trade names:

  • Atoris
  • Vasator
  • Liprimar
  • Tulip

  The pharmacist says: “Atorvastatin is usually prescribed by general practitioners and cardiologists as part of the complex treatment of cardiovascular diseases. Therefore, when they come to the pharmacy to buy prescribed drugs, people ask a logical question: what do Atorvastatin tablets help with.

  Atorvastatin is a lipid-lowering agent. In other words, the drug reduces the content of “bad” cholesterol in the blood. Due to this, it is used to treat hypercholesterolemia and reduce the risk of complications of heart and vascular diseases. For example, atherosclerosis and coronary heart disease.

  Atorvastatin before or after meals

  Atorvastatin tablets are taken by mouth regardless of food intake. It is important to note that before and during the use of the drug, it is recommended to follow a diet: minimize fat intake and completely abandon butter and palm oil.

  If you ask about the compatibility of Atorvastatin and alcohol, then the answer will be ambiguous. The intake of alcoholic beverages is not contraindicated when using the drug. However, abuse of Atorvastatin is not recommended, as active liver disease and elevated liver enzymes are on the list of contraindications. Therefore, it is important to be careful when taking medication and alcohol-containing drinks together.

  Atorvastatin: side effects

  • Nasopharyngitis – inflammation of the mucous membranes of the nasal cavity and pharynx
  • Allergic reactions: urticaria, pruritus
  • Increase or decrease in blood glucose
  • Headache
  • The appearance of a “veil” before the eyes
  • Tinnitus
  • Sore throat and epistaxis
  • Constipation or diarrhea
  • Nausea
  • Inflammation of the liver
  • Pain in muscles, joints and limbs
  • Increased liver enzymes

  Rosuvastatin or Atorvastatin: which is better

  Rosuvastatin and Atorvastatin belong to the same group of drugs – statins, but they belong to different generations. Atorvastatin is an earlier drug belonging to the third generation of drugs, while Rosuvastatin is the fourth – more modern. Therefore, the activity of Rosuvastatin against “bad” cholesterol is higher. So, Rosuvastatin is effective in doses from 5 mg to 40 mg, and Atorvastatin from 10 mg to 80 mg.

  Rosuvastatin also causes fewer side effects. However, its cost is higher. Only a doctor can replace Atorvastatin with Rosuvastatin.

  All products Rosuvastatin

  20 reviews

  Liprimar or Atorvastatin: which is better

  Liprimar is an original American drug, the active ingredient of which is Atorvastatin. Other Atorvastatin preparations have been replicated based on Liprimar’s evidence base.

  The drugs are similar: they have identical indications for use, dosages, contraindications, and are well tolerated by the body. Substituting one drug for another can be done at the pharmacy based on personal preference and affordability.

  All products Liprimar

  8 reviews

  Atorvastatin or Atoris: which is better

  Atoris is another drug with Atorvastatin as the active substance. Produced in Slovenia in dosages of 10 and 20 mg. The situation is similar with Liprimar: the drugs are similar in all therapeutic parameters.

  Atoris disadvantage: no 40mg dosage, causing patients requiring higher dosages to take more tablets. For example, if you need the highest dose of 80 mg, you will have to drink 8 tablets of 10 mg or 4 tablets of 20 mg.

  All products Atorvastatin

  22 reviews

  All products Atoris

  20 reviews

  Summary

  • Atorvastatin – tablets based on the same active ingredient in dosages of 10 mg, 20 mg, 40 mg and 80 mg.
  • Atorvastatin reduces the content of “bad” cholesterol in the blood.
  • Atorvastatin tablets are taken by mouth regardless of food intake.
  • Rosuvastatin and Atorvastatin belong to the same group of drugs – statins, but to different generations.
  • The activity of Rosuvastatin against “bad” cholesterol is higher.
  • Liprimar is an original American drug, the active ingredient of which is Atorvastatin.
  • Atoris is another drug with Atorvastatin as the active ingredient.

  Ask an expert about the topic of the article

  Still have questions? Ask them in the comments below and our experts will answer you. There you can also share your experience with other readers of Megasovets.

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  Statins – benefits and harms

  Currently, more and more attention is paid to human health. Various programs are being developed to identify hidden courses of diseases, medical examinations of the population are being carried out, in which special attention is paid to the level of cholesterol in the blood, an increase in which leads to an increased risk of heart attack and stroke, the development of atherosclerosis, the formation of blood clots and, as a result, severe cardiovascular illness and even death.

  According to statistics, mortality from cardiovascular diseases is in first place worldwide. Therefore, special attention should be paid to the importance and frequency of medical examinations, because the disease is better to prevent than to treat, and if we talk about cholesterol, then the deviation from the norm at an early stage is not physically felt and does not manifest itself, but the consequences to which this can lead are irreversible.

  What is cholesterol?

  Cholesterol (cholesterol) is an organic compound, a component of lipid (fat) metabolism, contained in the cells of all living organisms – about 20-30% of which enters the body with food, the remaining 80% is produced by the body.

  Fats themselves do not dissolve in the blood, this function is performed by a special class of proteins – lipoproteins. The body secretes total cholesterol, “good” cholesterol (high-density lipoproteins that transfer cholesterol to the liver) and “bad” (low-density lipoproteins – vice versa from the liver to tissues), therefore, when prescribing treatment, one should understand the change in the rate of which cholesterol led to the disease .

  Cholesterol is one of the main structural elements of the cell, as it provides its strength and membrane permeability, and is also involved in the production of both sex hormones and adrenal hormones, vitamin D, and bile acids. It is necessary to control its level, because fears are caused not only by an increase in cholesterol in the blood, but also by its decrease. This can cause: indigestion and digestibility of fats, depression, fatigue, disruption of the brain, bone fragility, in women – early menopause or amenorrhea, in men – impotence, the risk of developing cancer due to the weakening of the protective functions of the body.

  Cholesterol norm in the elderly

  The norms of cholesterol in the blood vary depending on age and gender, lifestyle and nutrition, but you should always remember that maintaining its level within the normal range is the key to healthy blood vessels. The normal level of cholesterol in the blood is considered to be an indicator not exceeding 5. 0 mmol / l, acceptable (borderline) – 6.5 mmol / l, and the numbers above indicate the development and progression of the disease.

  What are statins

  A group of drugs called to fight high cholesterol – statins (from the Latin “able to stop”) – they reduce the production of cholesterol in the liver and reduce its level in the blood by blocking the production of an enzyme involved in the formation of cholesterol, and they also help stabilize the growth of plaques on the vessels, reduce the risk of blood clots and the development of ischemic organ damage.

  The indication for the appointment of this group of drugs is a significant excess of cholesterol levels, prevention of stroke and heart attack, myocardial infarction, atherosclerosis (a disease in which plaques form on the surface of blood vessels that impede blood circulation in the organs).

  Today, statins are one of the most popular drugs that are prescribed not only for the treatment of diseases, but also for the prevention of vascular diseases, if indicated.

  Statin groups

  • Preparations of the statin group, depending on the active substance, the degree of exposure to a person, as well as the time spent on the pharmaceutical market, are divided into:

  • 1st generation drugs – lovastatin, pravastatin, simvastatin – they are also called natural, they are well effective, but have a large number of side effects and are poorly tolerated by the body;

  • The 2nd generation drugs – fluvastatin – are well absorbed by the body and reduce the possibility of side effects, therefore, increased dosages of these drugs are prescribed, which cannot but affect the body;

  • 3rd generation drugs – atorvastatin – more modern drugs with a stable effect, used for any age category, in addition to the main action, they also increase “good” cholesterol, they are mainly prescribed to older people because of better tolerance and availability;

  • 4th generation drugs – the latest drugs with high efficiency and safety, as well as minimal risks of side effects – rosuvastatin, pitavastatin.

  Statins: benefits and harms

  There is an opinion that statins are less useful than it is believed, they reduce cholesterol, but at the same time they have a negative effect on the body. Of course, we can agree with this, since they have side effects that are described in detail in the instructions for a particular drug.

  Side effects of statins:

  • decreased hormone levels,
  • memory problems occur,
  • maximum reduction in cholesterol levels, which can lead to cancer due to a decrease in the protective functions of the body,
  • development of diabetes,
  • allergic reactions,
  • muscle weakness,
  • convulsions,
  • neuritis of the facial nerve and others.
  • Negative consequences, typical of intoxication of the body, are also caused by an overdose of drugs – disruption of the gastrointestinal tract, allergies, sweating, etc.

  With properly prescribed treatment and strict adherence to the schedule of taking drugs, without gaps, taking into account the individual characteristics of the body, the risk of side effects is significantly reduced, and its effectiveness is increased.

  Benefits of statins

  Statins, in addition to their main function, also have anti-inflammatory and antitumor properties, antioxidant and antithrombotic effects.

  The effectiveness of the use of statins in the secondary prevention of diseases has been proven – this is when a drug of this group is prescribed to a patient after a heart attack or stroke, in order to prevent it again.

  Statins are a prescription drug, so only the doctor prescribes or cancels these drugs, determines the required dosage and duration of its administration (it is better to take them in the evening), since statins are not always combined with other drugs that the patient may take due to the presence of chronic diseases.

  The incompatibility of statins with other drugs can lead to serious consequences, so the attending physician must be aware of all the drugs taken. As a rule, in order to achieve a positive and sustainable result, statins are prescribed for a long time, and sometimes for life, since they have a cumulative effect and one can speak about their effect on the body only 3-4 weeks after the start of administration. It is also possible to cancel the drug (temporarily or permanently), but not on its own, but for medical reasons and under the supervision of a doctor.

  Statin treatment is prescribed, especially for the elderly, only after a long and ineffective diet aimed at lowering cholesterol levels (a strict special lipid-correcting diet can reduce cholesterol levels by 15-20%), lifestyle changes (giving up bad habits and unhealthy snacks, increasing physical activity). activity) and in each specific case, taking into account the presence of concomitant diseases in the patient, his age, compatibility with other drugs. Throughout the treatment process, cholesterol levels should be monitored periodically by conducting tests.

  In addition to the elderly, statins are prescribed with extreme caution to people with diseases of the liver, kidneys, organs of vision, diabetes mellitus. Absolute contraindications for the appointment of statins include severe liver disease, individual intolerance (may provoke allergic reactions), renal failure, pregnancy, and childhood.

  Natural statins

  In nature and folk medicine, there are many remedies that help lower cholesterol for those who, due to contraindications or side effects, cannot take medications – blackcurrant, mountain ash, wild rose, blackberry leaves, linden, flax seeds, pumpkin, in the form of decoctions and tinctures.

  Natural statins include foods such as fresh vegetables (carrots, tomatoes) and fruits, nuts (regardless of type), garlic, cereals, fatty fish, chicory, green tea. Herbal statins, of course, can lower the level of cholesterol in the blood, but with an advanced form of the disease, it is necessary to connect medications.

  To reduce cholesterol without the use of medicines, a balanced diet with a limited amount of fats (you should not completely exclude them), normalization of weight (in case of obesity), a healthy good sleep, giving up bad habits – alcohol, smoking, moderate physical activity helps.

  Should I take statins?

  There is also such a theory, most likely expressed by persons without a medical education, that “with age, the level of cholesterol in the body increases and after 60 years it stabilizes, respectively, all centenarians have high cholesterol, and an artificial lowering of its level leads to memory deterioration, development many deadly diseases. Cholesterol is an indicator of age, just like wrinkles.”

  Having read articles on the Internet or the media, reviews about the dangers of statins on the body, people are afraid to take them and are skeptical about doctors’ prescriptions, although in some cases they are vital.

  Despite the long-term use and stable position in cardiology, statins are still being carefully studied all over the world and unequivocal conclusions on them have not yet been made, but today we have confirmation of the negative effects of statins on the body and evidence of a decrease in the risks of developing heart attacks and strokes, especially in people prone to these diseases, as well as a decrease in the mortality rate from these diseases.

  In any case, if there are indications for prescribing this group of medications, the decision in the direction of the necessary treatment will be made by the doctor, taking into account the concomitant factors and control the process of recovery or steady state throughout the treatment.