Barium sulfate side effects: Barium Sulfate: MedlinePlus Drug Information
Barium sulfate (By mouth) | Drug Notes | Health Information
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Used to help view images of the body during a medical test or imaging procedure.
E-Z-Cat Dry, E-Z-Disk, E-Z-HD, E-Z-Paste, Entero VU, Liquid E-Z-Paque, Readi-Cat 2, Readi-Cat 2 Smoothie, Tagitol V, Varibar, Volumen
There may be other brand names for this medicine.
When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to barium.
How to Use This Medicine:
Cream, Liquid, Tablet
- A nurse or other trained health professional will give you this medicine. You will swallow the barium liquid just before your scan or procedure.
- Drink plenty of liquids after the test to help clear the barium from your body and to keep you hydrated. Barium may cause severe constipation.
- Follow all instructions you are given for your scan or procedure. Your doctor may tell you not to eat or drink anything the night before your test. Barium will work better if your stomach and bowels are empty.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, cancer, heart disease, trouble swallowing, or an allergy to other contrast agents. Tell your doctor about any digestion problems, including bleeding, ulcer, blockage, narrowing, diverticulitis, or recent surgery, trauma, or radiation treatment.
- This medicine may cause constipation, which could be severe.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, trouble breathing, or coughing up blood
- Fever, chills, cough, fast heartbeat, shallow breathing
- Sudden, severe stomach pain, nausea, vomiting with fever
- Trouble swallowing
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects.
You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 1/27/2017
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What to expect and side effects
A barium swallow is a type of test used to look inside the esophagus, or food pipe. A doctor might recommend this test if they need to look at the outline of any part of a person’s digestive system.
Barium is a white liquid that is visible on X-rays. Barium passes through the digestive system and does not cause a person any harm.
As it passes through the body, barium coats the inside of the food pipe, stomach, or bowel, causing the outlines of the organs to appear on X-ray.
Share on PinterestA barium swallow can help a doctor identify problems in the food pipe, stomach, or bowel.
A barium swallow test may be used if someone has any of the following conditions:
- frequent, painful heartburn
- gastric reflux, where food or acid keeps coming back up the food pipe
- difficulty eating, drinking, or swallowing
This test can give a doctor information about how the person is swallowing.
It can also reveal if someone has any of the following in their food pipe, stomach, or the first part of the bowel:
- abnormal growths
If someone has a tumor, this will show up on the X-ray as an irregular outline that extends from the wall of the affected organ.
People who are undergoing a barium swallow should not eat or drink for a few hours before the test. In some cases, the doctor may ask the person to stop taking medication before the test.
Some hospitals recommend not chewing gum, eating mints, or smoking cigarettes after midnight the night before a barium swallow test.
The test takes around 60 minutes and will take place in the X-ray department of the hospital. A person will need to change into a hospital gown.
People can bring a friend or relative for support. However, the companion will not be able to join them in the X-ray room.
In the X-ray room, the person drinks the barium liquid. It often has a chalky taste but can sometimes be flavored.
Share on PinterestA person will lie on a tilting table for part of the examination.
In some cases, a person will be given an injection to relax their stomach.
A person will be standing for some parts of the examination, and lying down on a tilting table for other parts. This allows the liquid to travel through the body, and for the radiologist and radiographer to take a selection of images.
People do not have to stay in hospital after the test and are free to go home as soon as it is complete. The results usually arrive within 1-2 weeks.
Risks and side effects
Patients may feel nauseous after a barium swallow test or become constipated. Drinking lots of fluids can help to relieve constipation. Symptoms of nausea should improve as the barium passes through the system.
It is normal for people to have white-colored stools the first few times they use the toilet after having a barium swallow test.
Some people might worry about being exposed to radiation as part of the X-ray process. However, the amount of radiation a person is exposed to is minimal.
Sometimes, the injection given to relax the stomach can cause temporary blurred vision.
People should not have a barium swallow test if they are pregnant.
If someone has glaucoma or heart problems and needs to have a barium swallow, the doctor may not give the stomach-relaxing injection.
If someone has diabetes then the doctor will schedule a morning appointment for the barium swallow.
If the person takes tablets to control their diabetes, the doctor will tell them not to take the medicine before the test. Instead, they should bring their tablets and some food to the exam to have after it is complete.
People who use insulin will be asked to miss their morning dose and maybe the previous evening’s dose. They should bring their insulin and some food to have after the test. However, those who take long-acting insulin should continue taking this.
Share on PinterestA barium enema allows doctors to examine the colon and rectum.
Another type of barium test is a barium enema. The barium enema test is similar to the barium swallow test and is used by doctors to examine the colon and rectum.
This test usually takes about 40 minutes. A person will be given a laxative the day before having a barium enema test. A laxative is a medicine that helps to clear out the bowel.
During the test, the person lies on their side on a table in the X-ray room. An enema containing barium and water is fed into their rectum through a small plastic tube. Air is also piped through the tube to inflate the bowel.
The table tilts, which spreads the barium throughout the colon. This allows the radiologist and radiographer to clearly see any lumps or swellings within the colon.
The person has to try and hold the liquid in the rectum while the test takes place. Afterwards, most of the liquid drains back into the tube and does not stay in the body.
After having a barium enema test, people may experience some cramping or diarrhea. As with the barium swallow, someone undergoing a barium enema may also have white stools the first few times they go to the toilet after the test.
There is a very small risk of the bowel lining tearing when having this test. This complication only tends to happen if the bowel is very inflamed.
Alternatives to a barium swallow test
An alternative to a barium swallow is a gastroscopy. In this procedure, a narrow, flexible, telescopic camera is used to look inside the food pipe, stomach and the first part of the small intestine.
A computed tomography (CT) scan may also be used in combination with a gastroscopy to provide X-ray images of the gut.
Active ingredient BARIUM SULFATE* (BARII SULFAS*)
- Pharmacological properties
- Indications BARIUM SULFATE*
- Application of BARIUM SULFATE*
- Side effects
- Special instructions
- Recommended alternatives
- Trade names
Medicines containing the active substance BARIUM SULFATE*
X-ray contrast agent. Due to the pronounced adhesive properties, an aqueous suspension of barium sulfate well envelops the mucous membrane of the gastrointestinal tract, provides a clear contrast of the microrelief of the mucous membrane and makes it possible to obtain a high quality x-ray image. Non-toxic, not absorbed in the gastrointestinal tract. Completely eliminated in 24–48 hours
for x-ray examination of the esophagus, stomach, small and large intestines.
Suspension is prepared with distilled water immediately before use. For x-ray examination of the esophagus, stomach and small intestine, it is taken orally, for irrigoscopy, it is administered rectally.
Inside for x-ray examination of the esophagus, stomach and small intestine is used as a paste or suspension. For tight filling of the esophagus, a 50% paste is used. Dosed with spoons. 1 tablespoon contains 30 g of paste (15 g of barium sulfate). If necessary, the paste can be diluted by adding 70 ml of distilled water at room temperature to 180 g of paste. For fluoroscopy of the esophagus, the dose of undiluted paste is 120-180 g, diluted with water in a ratio of 3: 1 – 200-250 ml. For X-ray examination of the stomach and small intestine, a suspension is prepared (from powder or paste). To prepare a suspension from a paste, 70-80 ml of boiled water is added in portions to 240 g in 2-3 doses and thoroughly mixed, 300-450 ml is used for one study of the stomach and small intestine. To prepare a suspension from a powder, mix it with warm boiled or distilled water in a ratio of 2:1 to 4:1 for adults and from 1:1.5 to 1:2 for children and mix thoroughly for 4-5 minutes (possibly using a mixer), the dose for adults per study is 300 ml, for children – 100 ml.
A more dilute suspension is used rectally for irrigoscopy: 700–800 ml of water is added to 240–360 g of paste; for one study – 1000-1500 ml.
hypersensitivity to barium sulfate, perforation of the esophagus, stomach or intestines, esophagotracheal fistulas, swallowing disorders, intestinal obstruction, constipation, stenosis of the esophagus, bleeding from the gastrointestinal tract, condition after surgical interventions on the gastrointestinal tract.
barium appendicitis, constipation, allergic reactions. When using gas-forming substances in the process of double contrasting, unpleasant sensations in the epigastric region may occur.
for double contrasting in adults and older children (double contrasting is not advisable in young children), immediately before the study, the patient is given, depending on age, 1.5–3.5 g of sodium bicarbonate (in solution or powder), which is quickly washed down with a solution of 1–3 g of citric acid. The total volume of distilled water should not exceed 7–15 ml. Can be used to study intestinal motility in children. After oral administration, the suspension passes through the small intestine in children in 1–2 hours, which makes it possible to study the structure and motor function of the small intestine in a short time and thereby abandon special techniques for studying it. The duration of the passage of the suspension through the colon is 4 hours, which significantly reduces the time of examination of the intestine and reduces the radiation exposure by 2 times.
instructions for use, price, analogues, composition, indications
active substance – barium sulfate.
White or almost white, fine, friable powder, odorless.
Radiopaque agent. Envelops the mucous membrane of the digestive tract and provides a clear image of the microrelief of the mucous membrane. Increases image contrast in x-ray studies of the gastrointestinal tract. The maximum contrast of the esophagus, stomach and duodenum is achieved immediately after oral administration, the small intestine – after 15-90 min (depending on the rate of gastric emptying and the viscosity of the drug). The greatest visualization of the distal small and large intestine depends on body position and hydrostatic pressure.
Low toxicity. It is not absorbed from the gastrointestinal tract and does not enter the systemic circulation. Completely excreted through the intestines after 24-48 hours.
Used as a radiopaque agent for visualization of the upper gastrointestinal tract (esophagus, stomach, duodenum) both by conventional X-ray and by double contrast.
Hypersensitivity; violation of the integrity of the walls of the gastrointestinal tract (suspicion of it), esophagotracheal fistulas; swallowing disorder, intestinal obstruction, constipation, stenosis of the esophagus, bleeding from the organs of the gastrointestinal tract; condition after surgical interventions on the organs of the gastrointestinal tract; malabsorption syndrome, food allergy; atresia; ischemic and necrotizing enterocolitis; injury or chemical burns of the gastrointestinal tract.
The general serious condition of the patient; bronchial asthma, dehydration.
Not recommended during pregnancy. If it is necessary to conduct a study during lactation, breastfeeding should be stopped within 24 hours after the study.
Inside, for x-ray examination of the pharynx, esophagus, stomach and small intestine: barium sulfate for fluoroscopy is used in the form of an aqueous suspension prepared immediately before the x-ray examination. To prepare a suspension from a powder, mix it with warm boiled or distilled water in a ratio of 2:1 to 4:1 for adults and from 1:1.5 to 1:2 for children and mix thoroughly for 4-5 minutes (possibly using a mixer), the dose for adults per study is 300 ml, for children – 50-100 ml.
From the digestive system: barium appendicitis, constipation; at
the use of gas-forming substances in the process of double contrasting – discomfort in the epigastric region.
Allergic reactions: urticaria, erythema, rash.
Barium sulfate is biologically inert and does not interact with other drugs. However, the presence of barium sulfate in the gastrointestinal tract may affect the absorption of other drugs taken at the same time.
Influence on the ability to drive a car or other mechanisms
Does not affect.
– The drug should be taken under medical supervision.
– Do not use in patients during and up to 4 weeks after radiotherapy to the rectum or prostate.
– After using barium sulfate to prevent constipation, it is recommended to drink an increased amount of fluid.
– Caution should be exercised when using barium sulfate in children, elderly and debilitated patients
– For double contrasting in adults and older children (double contrasting is not advisable in young children), immediately before the study, the patient is given, depending on age, 1.5-3.5 g of baking soda (in solution or powder), which is quickly washed down with a solution of 1-3 g of citric acid. The total volume of distilled water should not exceed 7-15 ml. Can be used to study intestinal motility in children. After oral administration, the suspension passes through the small intestine in children in 1-2 hours, which makes it possible to study the structure and motor function of the small intestine in a short time and, thereby, to abandon the special methods of its study. The duration of the passage of the suspension through the colon is 4 hours, which significantly reduces the time of inspection of the intestine and reduces the radiation exposure by 2 times.