How does biotin affect thyroid test results. What are the potential consequences of biotin interference in medical diagnoses. Why are more patients taking high doses of biotin supplements. How can healthcare providers identify and address biotin-related test interference.

The Rising Popularity of Biotin Supplements

Biotin, also known as vitamin B7, vitamin H, or coenzyme R, has gained significant popularity as a dietary supplement in recent years. Many individuals are turning to biotin supplements in the belief that they can improve hair, nail, and skin health. This trend has led to an increase in the number of people consuming biotin in doses far exceeding the recommended daily intake of 30 micrograms (mcg).

While a standard multivitamin may contain the recommended daily amount, some patients are taking biotin in milligram quantities – up to hundreds of times the suggested dose. The growing popularity of biotin supplements can be attributed to aggressive marketing strategies, including internet promotions and television advertisements. As a result, healthcare providers are encountering more patients who are unknowingly consuming high doses of biotin, often without considering it a medication worth mentioning during medical consultations.

Biotin Interference in Laboratory Tests

The increased consumption of high-dose biotin supplements has led to a concerning issue in medical diagnostics: biotin interference in laboratory tests. This interference can significantly impact the accuracy of various test results, particularly those related to thyroid function.

How Does Biotin Interfere with Lab Tests?

According to Dr. Stefan K. Grebe, professor of laboratory medicine & pathology at the Mayo Clinic, the problem lies in the fact that most modern immunoassays utilize biotin in their design. These assays rely on the strong attraction between biotin and streptavidin to either anchor antibodies to a capture surface or to capture them after they have reacted with a patient’s sample.

When a patient’s blood sample contains large amounts of biotin, it can interfere with this process, leading to inaccurate test results. The nature of this interference can vary depending on the type of assay:

• In competitive immunoassays (used for measuring substances like T4, T3, and cortisol), biotin interference typically causes falsely high results.
• In immunometric (sandwich) assays, biotin interference leads to falsely low results.

The extent of interference can also be influenced by factors such as the assay’s incubation time, with longer incubation periods increasing the opportunity for biotin to interfere with the results.

Impact on Thyroid Function Tests

Thyroid function tests are particularly susceptible to biotin interference, which can lead to misdiagnosis and inappropriate treatment of thyroid disorders. Dr. Cary N. Mariash, professor of clinical medicine at Indiana University, has encountered several cases where biotin supplementation caused confusing and inconsistent thyroid test results.

Case Study: Biotin-Induced Thyroid Test Abnormalities

Dr. Mariash presented a case at the International Thyroid Congress involving a patient with well-controlled hypothyroidism who suddenly showed abnormal thyroid function test results. The patient’s free T4 levels spiked despite normal thyroid stimulating hormone (TSH) levels. Further testing revealed elevated free T4 and total T3, but normal total T4, T4 index, and TSH.

The confusion was resolved when it was discovered that the patient had recently started taking 10 mg of biotin daily. Upon discontinuing the biotin supplement, the patient’s thyroid tests returned to normal, demonstrating that the abnormal results were due to biotin interference rather than an actual thyroid problem.

Potential for Misdiagnosis and Mistreatment

The biotin-induced interference in thyroid function tests poses a significant risk of misdiagnosis and inappropriate treatment. Dr. Carol Greenlee, an endocrinologist from Grand Junction, Colorado, has observed an increasing number of cases where biotin supplementation has led to confounding lab results.

Dr. Greenlee recounts a concerning example: “I saw somebody just yesterday who has had an extensive workup for hyperthyroidism. A lot of her tests look like she has Graves’, but she is taking massive doses of biotin. She probably doesn’t have any thyroid problem. We could be treating people for Graves’ disease who don’t have it, and that’s really scary.”

This scenario highlights the potential for serious medical errors resulting from biotin interference. Patients could be subjected to unnecessary treatments for conditions they don’t actually have, while their true health issues remain unaddressed.

Identifying and Addressing Biotin Interference

Given the prevalence of biotin supplementation and its potential impact on medical testing, healthcare providers must be vigilant in identifying and addressing this issue. Here are some strategies to mitigate the risk of biotin-related test interference:

1. Patient history: Always inquire about supplement use, specifically asking about biotin or supplements for hair, skin, and nail health.
2. Education: Inform patients about the potential impact of biotin on lab tests and the importance of disclosing all supplement use.
3. Temporary discontinuation: If biotin interference is suspected, consider asking patients to temporarily stop taking biotin supplements before laboratory tests.
4. Alternative testing methods: In cases where biotin interference is confirmed or suspected, explore alternative testing methods that are not susceptible to biotin interference.
5. Collaboration with laboratories: Work closely with laboratory professionals to understand which tests may be affected by biotin and what alternatives are available.

The Broader Implications of Supplement Interference

The issue of biotin interference in medical tests raises broader concerns about the potential impact of unregulated dietary supplements on healthcare. As the supplement industry continues to grow, it’s crucial for both healthcare providers and patients to be aware of the potential interactions between supplements and medical diagnostics.

Regulatory Considerations

The biotin interference issue highlights the need for improved regulation and oversight of dietary supplements. Unlike prescription medications, supplements are not subject to the same rigorous testing and approval processes. This lack of regulation can lead to unforeseen consequences, such as the widespread use of high-dose biotin supplements without full understanding of their potential impacts on medical testing.

Patient Education and Communication

Addressing the biotin interference problem also underscores the importance of effective patient-provider communication. Many patients may not consider supplements as “medications” and therefore fail to report their use during medical consultations. Improving patient education about the potential impacts of supplements on their health and medical care is crucial.

Advances in Laboratory Testing

The biotin interference issue has spurred efforts to develop more robust laboratory testing methods that are less susceptible to such interferences. Researchers and diagnostic companies are working on new assay designs and technologies that can provide accurate results even in the presence of high biotin levels.

Biotin-Insensitive Assays

Some laboratories have begun to implement biotin-insensitive assays for certain tests, particularly those commonly affected by biotin interference. These assays use alternative methods that do not rely on the biotin-streptavidin interaction, thus eliminating the potential for biotin-related inaccuracies.

Improved Detection and Correction Methods

Research is ongoing to develop methods for detecting and correcting biotin interference in existing assays. This includes the use of additional steps in the testing process to remove excess biotin from samples or to mathematically correct for its presence.

The Future of Personalized Medicine and Supplement Use

The biotin interference issue serves as a reminder of the complex interplay between dietary supplements, medical diagnostics, and patient care. As we move towards more personalized approaches to medicine, understanding and accounting for the impact of individual supplement regimens on diagnostic testing will become increasingly important.

Integrating Supplement Information into Electronic Health Records

One potential solution to the biotin interference problem and similar issues is the integration of comprehensive supplement information into electronic health records. This could allow for automated flagging of potential interactions between a patient’s supplement use and planned diagnostic tests or treatments.

Personalized Testing Protocols

As our understanding of supplement interactions grows, we may see the development of more personalized testing protocols. These could take into account an individual’s supplement regimen, adjusting testing methods or interpretation of results accordingly.

The issue of biotin interference in medical tests serves as a cautionary tale about the unintended consequences of seemingly harmless dietary supplements. It highlights the need for ongoing research, improved regulation, and better communication between healthcare providers and patients. As the landscape of personalized medicine and supplement use continues to evolve, staying informed and vigilant about potential interactions will be crucial for ensuring accurate diagnoses and appropriate patient care.

By addressing the biotin interference issue head-on, the medical community can not only improve the accuracy of thyroid function tests but also set a precedent for how to handle similar challenges that may arise in the future. This proactive approach will ultimately lead to better patient outcomes and a more robust, adaptable healthcare system.

January: Thyroid Month | Beware of Biotin

More patients are taking the dietary supplement biotin, which could be throwing off a number of test results from thyroid cancer to Graves’ disease.

The thyroid test results made no sense, so the patient’s primary care physician sought help from an endocrinologist. The physician had been treating the patient’s hypothyroidism successfully with levothyroxine for some time, when suddenly her free T4 levels spiked despite a normal thyroid stimulating hormone (TSH) level.

The physician referred the patient to Cary N. Mariash, MD, professor of clinical medicine at Indiana University in Indianapolis, where additional laboratory tests had inconsistent results: her free T4 and total T3 were elevated, but her total T4, T4 index, and TSH were normal.

Fortunately, Mariash could clear up the confusion by asking the patient a simple question: “Are you taking biotin?”

Yes, she replied, she had recently started taking 10 mg a day in hopes of improving her hair and nails. Her tests returned to normal when she stopped taking biotin. The problem had nothing to do with the patient’s thyroid — the biotin was interfering with the tests.

Mariash presented this case at the recent International Thyroid Congress because he has recently encountered several patients whose abnormal thyroid test results were caused by taking biotin and “most endocrinologists don’t know about this problem.”

Carol Greenlee, MD, an endocrinologist practicing in Grand Junction, Colo., concurs that she is encountering an increasing number of confounding lab results caused by patients taking large doses of biotin.

“I saw somebody just yesterday who has had an extensive workup for hyperthyroidism. A lot of her tests look like she has Graves, but she is taking massive doses of biotin. She probably doesn’t have any thyroid problem. We could be treating people for Graves’ disease who don’t have it, and that’s really scary.” — Carol Greenlee, MD, endocrinologist, Grand Junction, Colo.

“I saw somebody just yesterday who has had an extensive workup for hyperthyroidism. A lot of her tests look like she has Graves’, but she is taking massive doses of biotin. She probably doesn’t have any thyroid problem. We could be treating people for Graves’ disease who don’t have it, and that’s really scary,” Greenlee says.

An Unregulated Supplement
Many people have begun taking biotin mainly in the belief that it is a key contributor to keratin, and therefore can improve hair, nails, and skin. It is marketed under a number of names, including vitamin B7, vitamin H, and coenzyme R, and sometimes may be listed only as an unnamed supplement to improve hair and nails.

It is a B vitamin, and the Institute of Medicine recommends a daily intake of 30 mcg. That’s what a multivitamin such as Centrum Silver contains. But some patients, like the one Mariash treated, are taking milligram amounts, and might not consider it a medication, so not worth mentioning. It is marketed over the Internet, and Mariash recently saw a television advertisement for it, so its popularity could continue to grow.

An Issue with Assays
The problem is that almost all immunoassays today contain biotin because they rely on the biotin–streptavidin attraction to either anchor the assay’s antibodies to a capture surface or capture them once they have reacted with a patient sample, according to Stefan K. Grebe, MD, PhD, professor of laboratory medicine & pathology and co-director of the endocrine laboratory at the Mayo Clinic in Rochester, Minn.

Biotin At A Glance

• Many patients are taking megadoses of biotin that can cause falsely high and falsely low results in a variety of laboratory tests, including thyroid tests.
• Patients are taking these supplements mainly to improve their hair, skin, and nails — and might not consider them medications to report on their list.
• Biotin interference with lab tests could be causing misdiagnoses — and even mistreatment — in an unknown number of patients. [/pullout-wide]

Large amounts of biotin in a patient sample can interfere with this process. However, the effects can be confusing because, depending on the particular assay, biotin can skew the results to be either falsely high or falsely low. In the case of competitive immunoassays — usually used for low molecular weight targets (such as T4, T3, and cortisol) — biotin interference causes a falsely high result. In immunometric (sandwich) assays, it gives a falsely low result.

Other characteristics of the assay can also make a difference. For instance, a longer incubation time increases the opportunity for interference. Different assays for various analytes, even from the same manufacturer, can therefore vary in their susceptibility to biotin interference.

At the laboratory Mariash uses, the free T4 and total T3 assays use a biotin-streptavidin fluorescent detection system, so biotin can cause falsely elevated results, but the TSH and total T4 assays are not affected. In contrast, at Greenlee’s lab, biotin can lead to falsely low TSH results, but free T3 and free T4 tests are not affected. Biotin can also cause her lab’s assay for thyrotropin receptor antibodies (TRAb) to be falsely positive, which could lead to a misdiagnosis of Graves disease.

Mariash says that even though he suspected what was causing the questionable results, getting to the bottom of the problem was not easy: “I had to make a lot of phone calls to our laboratory. Finally a supervisor told me what platform they were using. Then I called the test manufacturer to get additional details, and they gave me enough information to know what was going on. But of course, they don’t give you every detail because some of it is proprietary.” Mariash’s laboratory director was unaware that biotin could be a problem.

Grebe says it may fall to the physician ordering the test to be vigilant: “When your lab results don’t make sense in terms of the clinical picture, or in terms of the constellation of lab results you have received, you should always think first of an assay interference — one of which is biotin — before you think of really exotic reasons for this to have happened, such as TSH-secreting pituitary tumors. ”

Puzzling Tests and a Revelation
Greenlee had an example of these confusing results when a patient was referred to be evaluated for a possible diagnosis of adrenal carcinoma. The patient had presented complaining of fluid retention and weight gain. Her face was red and she was growing hair on her face while losing hair on top of her head. Her cortisol and testosterone test results were elevated off the charts. Her thyroid tests were also confusing, with low TSH but normal T4 and T3.

“When your lab results don’t make sense in terms of the clinical picture, or in terms of the constellation of lab results you have received, you should always think first of an assay interference — one of which is biotin — before you think of really exotic reasons for this to have happened, such as TSH-secreting pituitary tumors.” — Stefan K. Grebe, MD, PhD, professor, laboratory medicine & pathology; co-director, endocrine laboratory, Mayo Clinic in Rochester, Minn.

A normal adrenal CT scan ruled out cancer. Greenlee asked the woman to come back the next morning for fasting blood tests. This time her tests were normal. Greenlee thought that perhaps there was some mix-up at the lab, and the original tests were not this patient’s.

The solution to the mystery only emerged over time. The patient’s problems stemmed from her home remedies for her hair loss — minoxidil and biotin. Not knowing her hair loss was not unusual for an older woman, and despite warnings that it should not be used by women, she was putting minoxidil on the top of her head — resulting in a red, hairy face.

The final piece of the puzzle fell into place when Greenlee was preparing a talk and came across a reference to biotin interfering with a parathyroid hormone assay. Her research following up this clue led her to literature reports of other biotin interferences. In the case of this patient, because she had been told to fast before she was tested again, she had not taken biotin, so those results reflected her true status. The biotin interference contributed to her out-of-kilter cortisol, testosterone, and TSH results. In unraveling the mystery, Greenlee consulted with Grebe to learn more about the ins and outs of immunoassays and worked closely with her lab — making them aware of the potential interference.

Biotin Vigilance
Greenlee is now making sure her practice identifies any patients taking the supplement: “We have huge signs in my office that ask people if they are taking biotin — in each exam room, over the phlebotomy chair, and at the front desk. We had all these nice pictures on our walls, but the biotin thing alarmed us so much that we don’t care about our decorations in our office anymore.”

“It can be dangerous not to recognize it,” Mariash agrees. He also notes that clinicians need to be vigilant because laboratories can change the test platform without notice.

For the interference to occur, the patient’s biotin level needs to be high — at least three times the upper limit of the healthy adult reference range, according to Grebe. But that level is easy to achieve with the megadoses many are taking.

Grebe suggests that a clinician can ask the lab to try using another manufacturer’s test, but an easier route is to ask the patient to stop the biotin then get retested. Biotin is water soluble, so it washes out of the body quickly — even a single day can make a big difference in the test results.

And although literature reports mostly focus on problems with parathyroid and thyroid hormone tests, biotin interference could be considered as a potential contributor to almost any suspicious immunoassay result.

Published by the Endocrine Society, Endocrine News is a monthly publication that offers an in-depth look at endocrinology trends and research, from reproductive issues to biotin concerns to thyroid problems. When you’re looking for the latest studies, interviews and commentary on endocrinology, you can find it on our site. With that in mind, if you’re interested in reading additional content with timely, accurate information on thyroid issues, check out our other articles such as “Fairytales: Dispelling Pediatric Thyroid Cancer Myths” and “Thyroid Cancer and Radioiodine. ”

Seaborg is a freelance writer based in Charlottesville, Va. He wrote about expanding the definition of osteoporosis in the December issue.

Benefits And Side Effects · HealthKart

Using biotin for hair is a popular option these days when it comes to hair growth & nutrition. But what is biotin and what are other benefits of biotin? Let’s read to find out!

Don’t we all dream of luscious healthy hair? But daily damage, heat, pollution, chemicals, and styling can damage your hair. Another damaging factor is not eating a healthy balanced diet. We need the right amount of vitamins and minerals in our diet for our skin and hair to be healthy. One such vitamin is biotin.

Table of Contents

What Is Biotin? 

Biotin, or Vitamin B7, is a part of the vitamin B complex group. It is a water-soluble vitamin and is associated with healthy hair and skin, cardiovascular, nerve, and digestive functions. The word biotin comes from the Greek word ‘biotos’ which means life or sustenance. Since it is a water-soluble vitamin, our body doesn’t store biotin.

Image Source: www.medme.pl

Biotin is a nutrient that helps us look young and attractive. It plays a pivotal role in maintaining your hair, skin, and nails. It has gained popularity in recent times and is easily available in supplement form as well. You can biotin tablets online or from a pharmacy, but consult your dermatologist to know whether biotin will suit you or not.

The daily requirement of biotin varies at every stage of life. 

• 5 micrograms daily for infants
• 6–8 micrograms daily for infants ages 1–3 years
• 12 micrograms daily for children ages 4–8 years
• 20 micrograms daily for children ages 9-13 years
• 25 micrograms for adolescents (14-18)
• 30 micrograms for male and female adults over 19
• 30 milligrams for pregnant women and 35 milligrams for women who are breastfeeding

Start with a lower dose and gradually increase the dosage as per your doctor’s recommendation.  The one important thing about taking biotin capsules or biotin supplements is that they shouldn’t be taken on an empty stomach. Always take biotin tablets with meals.

5 Health Benefits of Biotin 

Biotin is known for its benefits and for hair growth. But there are various other health benefits of biotin –

​

Image Source: mind, body and food

1. It is used by the body to metabolize carbohydrates, amino acid supplements, and fats.
2. Is beneficial in fetal development during pregnancy. It is also an important nutrient that is needed during breastfeeding. During pregnancy, the biotin requirement goes up, and this is one reason that a large number of women tend to get biotin deficiency during pregnancy.
3. Can regulate blood sugar. People with type 2 diabetes usually have low biotin level, taking biotin supplements will help them regular their blood sugar.
4. It is important for energy production in the body. Various enzymes need biotin for proper functioning.
5. Can solve the problem of brittle nails.

Image Source: img.grouponcdn.com

Biotin for Hair

It is a common myth that biotin is the sole ingredient needed for hair growth. Although biotin for hair growth is extremely important, but the biotin isn’t the only nutrient needed. A balanced mix of vitamins and minerals promotes hair growth.

How does biotin help in hair growth?

Our hair is made up of keratin, a type of protein. Proteins are formed by amino acids. And these amino acids are formed on reaction of enzymes with biotin. The biotin present in our body contributes to give healthy hair, skin, and nails. When ingested, either from food sources or from biotin supplements, it reacts with cell enzymes and produces amino acids, the building blocks of protein. This helps in hair growth. But apart from biotin, you need to eat food with a healthy balance of vitamins supplements and minerals, follow the stress-free lifestyle, and take proper care of your hair. If any one of these factors is missing, it may affect your hair. Hair loss and thinning of hair are commonly seen. A major cause is an erratic lifestyle – junk food, harsh chemicals, heat styling, hair coloring, pollution, and heat all cause hair damage in more than one way.
Biotin can be found in food. There are various sources of biotin. But a lot of people fall short of the daily requirement and take biotin supplements for healthy hair. It is essential that you talk to your doctor and then take biotin tablets.
If you want thick luscious hair, then biotin is the answer for you. Consume biotin rich food or biotin tablets. But keep in mind not to exceed the prescribed dosage. An overdose of biotin may cause medical complications.
Read on to find out what are the side effects of biotin.

Biotin Deficiency 

Biotin deficiency is very rare. But when it occurs the most common symptoms are –

• Dry flaky skin
• Hair loss
• Brittle hair
• Brittle nails
• Digestive tract issues
• Cramps
• Muscle pains
• Tingling in limbs
• Mood changes
• Nerve damage

Image Source: healthline

20 Food Sources of Biotin 

There are actually eight forms of Vitamin B7. But only one form occurs naturally, the one found in food sources. Thus, getting your daily dose of vitamins and minerals from food is always a good idea.

1. Liver
2. Egg yolk
3. Salmon
4. Cheese
5. Avocado
6. Cauliflower
7. Raspberries
8. Whole wheat bread
9. Mushroom
10. Cucumber
11.  Oats
12. Wheat germ
13. Nuts
14. Strawberry
15. Chicken
16. Carrot
17. Banana
18. Soy flour
19. Leafy greens
20. Legumes – soybean

Other Rich Sources of Biotin

• Safflower seeds
• Oyster mushroom dried
• Paneer
• Onion stalk
• Capsicum
• Broad beans
• Parsley
• Dates (processed)
• Broad beans
• Litchi
• Papaya

Biotin Side Effects 

A lot of people take biotin tablets for hair or biotin capsules. But we recommend that you talk to your doctor before taking biotin capsules.
Here are some of the biotin side effects that you must know.

Image Source: healcure

1. May cause acne 
The one thing that we all dread is acne. One of the worst side effects of biotin, if taken in high dosage is that it may cause cystic acne.
Biotin increases the production of sebum which causes dirt, oil, and grime to accumulate on your face. If you feel cystic acne, especially along your jaw line and chin, then biotin intake may be a cause of it.
The acne does fade away after a few weeks when you stop taking biotin. But it may leave some nasty marks and acne scars, which nobody is a fan of.

2. Can cause complications during pregnancy 
If you’re pregnant, you should avoid taking biotin. If you already take biotin for hair growth or biotin supplements, it is recommended to talk to your doctor. High dosage of biotin may increase the risk of miscarriage.

3. Allergic reactions
There are chances that some people may suffer from allergic reactions on intake of biotin capsules. Since each of us is different, the way each body reacts to biotin also varies.
The allergic reactions may include –

·    Feeling of nausea
·    Tightness in throat
·    Chest pain
·    Itchy rashes
·    Swelling of face and throat
If you see any of these signs after taking biotin capsules, it is best to consult a doctor immediately.

4. Nausea
A lot of people complain of nausea during the early stages of intake of biotin supplements. This isn’t a major cause of concern, because with time nausea with ease off.

5. Drug interactions 
Studies reveal that biotin has a negative interaction with anti-seizures and cholesterol-lowering medications. An increased dosage of biotin can interfere in the efficiency of these drugs. It can also have adverse effects for diabetes.
Talking to your doctor before starting to take biotin supplements is what should help.

6. Diarrhea 
Stomach cramps and diarrhea are common in individuals who take a high dosage of biotin. If you are taking biotin supplements and notice diarrhea or have stomach cramps, it is best to stop taking biotin tablets and talk to your doctor immediately.

7. Frequent urination 
In some cases, high dose of biotin may increase the need for urination. Apart from excessive urination, increased use of biotin may also cause excessive sweating.

So, here’s all that you want to know about biotin – biotin for hair, biotin benefits, biotin side effects, and lots more. It’s now time to take your first step towards healthy hair and overall fitness. 

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role for the human body and how to take it correctly

Content

• 1 Biotin b7: why is it necessary for the human body and how to take it correctly
  • 1. 1 The role of biotin b7 for human health
    • 1.1.1 The functions of biotin b7 in the human body 900 10
    • 1.1.2 Biotin b7 intake norms
    • 1.1.3 How to take biotin b7 correctly
  • 1.2 The importance of biotin b7 for the human body
  • 1.3 Where is biotin b7 found in nature?
  • 1.4 Indications for use of biotin b7
    • 1.4.1 Maintaining healthy hair, skin and nails
    • 1.4.2 Maintaining a healthy nervous system
    • 1.4.3 Maintaining a healthy hormonal system
    • 1.4.4 Maintaining a healthy heart and vessels
  • 1.5 How to take biotin b7 correctly?
  • 1.6 Biotin contraindications b7
    • 1.6.1 Hypersensitivity to biotin
    • 1.6.2 Thyroid problems
    • 1.6.3 Kidney problems
    • 1.6.4 Certain medications
    • 1.6.5 Pregnancy and breastfeeding
  • 1.7 Biotin b7 side effects and prevention
    9 0005 1.7.1 Possible side effects of biotin b7
    • 1. 7.2 Prevention of side effects of biotin b7
  • 1.8 Compatibility of biotin b7 with other drugs
  • 1.9 How to choose a quality drug with biotin b7
  • 1.10 Q&A:
    • • 1.10.0.1 What is biotin b7 and why does the human body need it?
      • 1.10.0.2 Which foods contain biotin b7?
      • 1.10.0.3 What dosage of biotin b7 should be used in order not to exceed the norm?
      • 1.10.0.4 Can I take biotin b7 to strengthen my hair and nails?
      • 1.10.0.5 Can nutrition be the cause of biotin b7 deficiency?
      • 1.10.0.6 What side effects can occur if the daily amount of biotin b7 is exceeded?
  • 1.11 How to supplement your diet with biotin b7 naturally
    • 1.11.1 Fish and seafood
    • 1.11.2 Fruits and vegetables high in biotin
    • 1.11 .3 Vitamin complexes
  • 1.12 Related videos:

Learn about the importance of Biotin B7 in the human body and how to take it correctly. Tips and advice from experts in the article on our website.

Vitamins and minerals are essential elements for the life of the human body. Biotin b7, also known as vitamin H or coenzyme R, is one such essential nutrient. This vitamin is key for the proper metabolism of carbohydrates, fats and proteins, as well as the protection of skin, hair and nails.

Unfortunately, like many other vitamins, our body cannot produce it on its own. As a result, it must be obtained from external sources such as food or additional intake of natural or synthetic drugs. However, as with any vitamin, you need to know how to properly take biotin b7 for best results.

In this article, we will talk about the important role that biotin b7 plays in the human body and how to take it correctly to get the most benefit from this vitamin.

The role of biotin b7 in human health

Functions of biotin b7 in the human body

Biotin b7 is an essential B vitamin that plays a key role in the metabolism of carbohydrates, proteins and fats. It is necessary for the correct functioning of several enzymes, including adenosine triphosphate, which regulate the conversion of food into energy.

Biotin b7 also helps improve skin, hair and nail health by supporting cell regeneration and maintaining the health of keratin, the protein that forms the basis of skin, hair and nails. It also plays an important role in fetal development as it helps regulate the production and use of glucose in both mother and baby.

Intakes for biotin b7

The optimal level of biotin b7 intake for a healthy person is between 30 and 100 micrograms per day. Although deficiency of this vitamin is rare, people who consume large amounts of raw egg protein foods may need additional doses. Also, people with digestive disorders, such as chronic diarrhea or malabsorption disorders, may need large doses of biotin b7.

How to take biotin b7 correctly

Biotin b7 can be obtained exclusively through food or as a supplement to food. It is perfectly absorbed by the body, and therefore does not require special conditions for its intake. In order to get enough biotin b7, it is recommended to consume foods such as eggs, meat, oatmeal, peas, peanuts, onions, mushrooms, whole grain bread, seeds and nuts. If you think you may need an extra serving of this vitamin, talk to your doctor, who may recommend an additional food supplement.

Importance of biotin b7 for the human body

Biotin b7 is a vitamin that the human body needs for the proper functioning of cells and metabolic processes. It is involved in the formation of structural components of cells, such as keratin, the main protein in hair, nails and skin, and generates energy in the body. Biotin b7 is also necessary for the formation of glucose and the synthesis of fatty acids necessary for the functioning of the nervous system.

Biotin b7 can be obtained from foods such as eggs, animal organs, fish and nuts, but some people may be deficient in this vitamin. Inadequate intake of b7 biotin can lead to nail, hair, and skin problems such as brittle nails, hair loss, and skin rashes. Also, a deficiency of biotin b7 can lead to digestive and nervous system problems.

If biotin b7 is deficient, it is recommended to increase its intake through food or supplements. However, it should be remembered that excess biotin b7 can also be harmful to the body, so it is important to follow the instructions for taking the dosage, and it is better to consult a doctor or nutritionist.

Where is biotin b7 found in nature?

Biotin B7 is a B-vitamin found primarily in plant foods. These foods include green vegetables such as spinach or broccoli, as well as nuts, seeds, and grains, including rice, wheat, and oats.

Biotin is also found in various types of meat products such as chicken, beef and pork. Fish like mackerel and salmon also contain biotin.

In addition, biotin can be obtained from other sources. For example, biotin is often added to various vitamin complexes and dietary supplements, and is also used as a food additive to improve the quality of food.

• Spinach
• Nuts and seeds
• Cereals
• Chicken, beef and pork
• Mackerel and salmon

It is recommended to obtain biotin from natural sources, but in case of deficiency, it can be additionally taken in the form of special supplements. In any case, it is always recommended to consult your doctor before starting dietary supplements.

Biotin b7 indications

Healthy hair, skin and nails

Biotin b7 plays an important role in the formation of keratin, the main component of hair, skin and nails. With a lack of biotin, baldness can occur, dryness and irritation of the skin will appear, hair can become brittle and dull, and nails can become brittle and easily broken.

Maintaining a healthy nervous system

Biotin b7 is involved in the synthesis of myelin, a substance that ensures the normal conduction of nerve impulses. A lack of biotin can lead to various neurological problems such as depression, irritability, and cognitive and coordination disorders.

Maintaining a healthy hormonal system

Biotin b7 is involved in the formation of hormones that regulate metabolism, as well as in the formation of glycogen – an energy store in the liver and muscles. Because of this, a lack of biotin can lead to digestive disorders, hypoglycemia, and other metabolic problems.

Cardiac and vascular health

Biotin b7 is involved in fat and protein metabolism, which can affect cardiovascular health. Because of this, a lack of biotin can lead to risks of developing cardiovascular disease.

• The recommended daily dose of biotin b7 is 30 mcg.
• Biotin b7 can be obtained from both food and nutritional supplements.

How to take biotin b7 correctly?

Biotin b7 is a vitamin responsible for the health of our skin, hair and nails. It also plays an important role in the absorption of nutrients, as well as in maintaining normal blood glucose levels.

The daily biotin requirement for adults is about 30 micrograms (mcg) per day. However, if you have any skin, hair, or nail health issues, you should see your doctor, who may recommend a vitamin supplement.

Biotin can be obtained from foods such as eggs, nuts, soybeans, oatmeal and spinach. However, if you prefer to take biotin as a supplement, follow the instructions on the package and do not exceed the recommended dose.

You can take biotin at any time of the day, but it’s best to take it at the same time each day. It is very important to follow the recommended dosage as overdosing on vitamins can be hazardous to your health.

• Find a quality biotin supplement, make sure it fits your needs.
• Take your vitamin regularly according to package directions.
• Watch the dosage!

In general, if you are healthy and have problems with your nails, hair, or skin, you are most likely getting enough biotin from your food. However, if you are in doubt, follow the recommendations given or seek the advice of your doctor, who will determine the most appropriate dose for you.

Biotin contraindications b7

Hypersensitivity to biotin

Some people may experience an allergic reaction to biotin. If you have ever had an allergic reaction to this vitamin, you should avoid it.

Thyroid problems

Biotin may affect thyroid function. If you have any thyroid problems, be sure to check with your doctor before taking biotin.

Kidney problems

People with kidney problems may have elevated levels of biotin in their blood. In this case, the use of biotin should be coordinated with the doctor.

Taking certain medications

Some medications can interfere with the absorption of biotin in the body. If you are taking any medications, be sure to let your doctor know before you start taking biotin.

Pregnancy and breastfeeding

Data on the safety of biotin during pregnancy and breastfeeding are insufficient. Therefore, biotin should be taken during this period only as prescribed by a doctor.

Side effects of biotin b7 and their prevention

Possible side effects of biotin b7

Most people tolerate biotin b7 without any side effects. However, some people may experience the following side effects:

• Skin rash
• Diarrhea
• Orthostatic hypotension – drop in blood pressure when standing up quickly due to dizziness and weakness
• Allergic reaction (eg, hives, swelling of the throat, asthma attack) )

Prevention of side effects of biotin b7

To reduce the chance of side effects, take biotin b7 as directed:

• Follow the recommended dosage
• Take biotin with food
• Drink plenty of water
• Do not exceed the recommended dose without a doctor’s prescription 9 0010
• Contact see your doctor if you experience any side effects

Remember that b7 biotin is not always the best solution to health problems. For the majority of people, biotin b7 is safe and beneficial, however, if you have concerns or questions about taking biotin b7, you should consult your doctor before using this vitamin.

Compatibility of biotin b7 with other drugs

Biotin b7 is a solvent group B vitamin with many beneficial properties for the body. Some people take it as an adjunct to treat hair, nails, skin, and improve digestion. However, when taking biotin b7, interactions with certain medications are possible, which can affect its effectiveness, as well as cause negative side effects.

Preparations from the antibiotic group (such as ampicillin, ciprofloxacin) may affect the absorption of biotin b7. To avoid disturbing the normal functioning of the body, it is necessary to observe an interval of two hours between taking antibiotics and biotin b7.

• Salicylates may decrease blood levels of biotin b7. Therefore, it is necessary to take biotin b7 as an additional drug only after consulting with your doctor.
• Metformin preparations (used in the treatment of diabetes) may impair the absorption of biotin b7. People who take metformin should check with their healthcare provider before taking supplemental biotin b7.

In general, when biotin b7 is used correctly according to dosage recommendations, the risks of interactions with other drugs are minimal. However, before starting to take additional vitamin complexes, it is necessary to consult with your doctor in order to avoid undesirable health consequences.

How to choose a quality biotin b7 product

Biotin b7 is an important vitamin for healthy skin, hair and nails. It also plays a role in metabolism and supports the health of the nervous system. When it comes to choosing a quality biotin b7 product, you don’t have to compromise on quality.

Before buying a drug, be sure to check the manufacturer and make sure they are known for their quality and reputation in the market. Also pay attention to the composition of the drug – the amount of biotin b7 in one serving should be indicated.

• Choose drugs that are certified and meet safety standards.
• Read customer reviews and expert recommendations.
• Compare prices from different manufacturers and choose the best offer.

To get the best benefit from taking biotin b7, it is important to take it correctly. Follow the instructions on the package and do not exceed the recommended dose. It is best to take the drug after meals to increase its absorption.

Remember that only a quality biotin b7 preparation can reach its full potential for healthy skin, hair and nails. Follow the recommendations for the choice of drug and dosage to get the best result.

Q&A:

What is biotin b7 and why does the human body need it?

Biotin b7 is a vitamin of group B, necessary for the regulation of the metabolism of carbohydrates, proteins and fats in the human body. It also plays an important role in the health of the skin, hair and nails, and supports the functioning of the nervous system.

Which foods contain biotin b7?

Biotin b7 is found in foods such as eggs, milk, nuts, whole grains, soybeans, bananas, and some meats and fish.

What dosage of biotin b7 should be used in order not to exceed the norm?

The adult recommended intake for biotin b7 is 30-100 micrograms per day. Exceeding this dosage can lead to serious consequences, including digestive and skin problems. Therefore, it is not recommended to exceed the daily allowance when taking biotin.

Can I take biotin b7 to strengthen my hair and nails?

Yes, biotin b7 is often used to strengthen hair and nails. It can help improve their quality, but you need to understand that biotin b7 is not the only factor responsible for the health of hair and nails, and its intake should be combined with proper nutrition and care.

Can nutrition be the cause of biotin b7 deficiency?

Yes, biotin b7 deficiency can occur in people whose diet does not contain enough foods rich in this vitamin. Also, the risk of deficiency increases with alcohol consumption in large quantities, with certain medications and with various diseases.

What side effects can occur if the daily amount of biotin b7 is exceeded?

Exceeding the daily allowance of biotin b7 may cause digestive problems, as well as skin manifestations such as rash and itching. However, taking biotin b7 in dosages less than the daily allowance should not cause side effects.

How to naturally supplement your diet with biotin b7

Fish and seafood

Fish products are one of the best sources of biotin b7. Among them: sardines, anchovies, sea bass and salmon. No less useful are: shrimp, squid and other seafood.

• Sardines are the most popular and affordable type of fish high in b7 biotin.
• Salmon – In addition to biotin, it is a good source of omega-3 fatty acids, essential for heart and brain health.
• Seafood – contains not only biotin, but also other useful vitamins and minerals that are necessary to strengthen the immune system and normal functioning of the body.

Fruits and vegetables rich in biotin

Some fruits and vegetables also contain biotin b7. These include: potatoes, avocados, bananas, mushrooms, nuts, and eggs.

1. Avocado is a rich source of biotin and also contains other nutrients such as vitamin C, K and fiber.
2. Mushrooms – uplifting as they contain magnesium and their rich flavor and soft texture are especially beneficial for vegetarians and vegans.
3. Eggs are not only a good source of biotin, but also other nutrients, including proteins and iron.

Vitamin complexes

If you want to make sure you get enough b7 biotin, you can include vitamin complexes in your diet. They can be purchased without a prescription and include the right amount of biotin as well as other essential vitamins and minerals.

Product Biotin content (per 100 g)

Related video:

Biotin, aka vitamin B7: benefit to the body or harm?

Biotin (vitamin H, B7, coenzyme R, coenzyme R) is one of the B vitamins that performs many functions in the body. This compound is part of the enzymes that regulate the metabolism of proteins, fats and carbohydrates, is a source of sulfur necessary for the synthesis of collagen, participates in the activation and transfer of CO ₂ . Biotin is necessary for the nervous system and beneficial intestinal microflora, and is also important for the health of hair, nails and skin, which is why it was called the “beauty vitamin”.

The name of the compound comes from the ancient Greek word “biotos”, which means “life”. Vitamin b7 is produced by the intestinal microflora, but it does not accumulate well in the body. It needs a lot of magnesium to be absorbed. In addition, biotin metabolism is inhibited by saccharin, raw egg protein (avidin), foods with preservatives E221 – E228, cooked oils, alcohol, antibiotics, drugs containing sulfur, etc.

Health benefits of biotin

Vitamin biotin is necessary for the metabolism of fats, carbohydrates and proteins, is a coenzyme for enzymes from the lyase class, is involved in the synthesis of amino acids (isoleucine and valine) and fatty acids, as well as in the production of glucose.

Vitamin H is important for healthy nails, hair and skin. Deficiency of this compound has been linked to seborrheic dermatitis and red, scaly skin rashes. It is necessary for pregnant and lactating women, both for themselves and for the fetus: animal studies have shown that its deficiency during pregnancy can cause birth defects in offspring.

Due to its ability to reduce glucose levels, vitamin B7 is useful for diabetics. Some placebo-controlled studies have shown that glucose concentrations in people with type 2 diabetes are significantly lower with sufficient amounts of biotin in the blood. A study of this topic has shown the ability of the vitamin to prevent kidney damage in people with insulin-dependent type 1 diabetes.

The beneficial effect of high doses of coenzyme in the treatment of progressive multiple sclerosis has been experimentally proven.

Daily value for the body

The recommended daily dose of biotin, in principle, does not exist, since there is no exact evidence to establish its amount in the body. However, the American National Academy of Medicine (IOM) considers an adequate intake of 30 to 100 micrograms per day for adolescents and adults 19 years of age and older.

Most people can take biotin supplements in sufficient doses, and few report mild side effects such as nausea and digestive problems. Since biotin is soluble in water, the excess amount will leave the body during urination.

Who needs biotin

Biotin is a “native” substance for the body. With a good microflora, intestinal bacteria are able to produce it in more than sufficient quantities. In addition, it is available in a wide range of foods, so deficiency is not common in humans. However, with irrational nutrition, certain diseases, genetic characteristics, disturbed intestinal microflora, as well as alcohol abuse, which prevents the absorption of vitamins, there may be a lack of coenzyme R.

Additional intake of vitamin B7 may be required in the following cases:

Pregnancy . During this period, a woman needs an increased intake of all vitamins. Deficiency of the h vitamin can lead to abnormal fetal development. Doctors recommend taking 30 micrograms of biotin per day in addition to folic acid.

Type 1 and 2 diabetes . Research published in 2016 showed that vitamin B7 may help with glycemic control in people with diabetes by lowering blood glucose levels. Animal experiments have shown that it stimulates insulin secretion from the pancreas and subsequently lowers blood glucose levels. The results are promising, but more research is needed before a definitive effect of biotin on blood sugar levels can be confirmed.

Biotinidase deficiency . Another cause of vitamin H deficiency is an autosomal recessive metabolic disorder. In people with this disease, the body does not produce enough of the enzyme needed to release biotin from proteins in the diet during digestion or due to normal protein metabolism in the cell. Profound or partial biotinidase deficiency occurs in 1 in 60,000 newborns when the enzymatic activity is between 10% and 30%.

Control of neuropathy . Vitamin B7 supplementation may help reduce nerve damage in people on dialysis for kidney disease. In 1990, scientists found that three patients who took a large dose of biotin for 1-2 years improved their symptoms. Vitamin H is essential for pyruvate carboxylase activity, without which high levels of pyruvate and aspartate can occur, negatively affecting the functioning of the nervous system. However, further evidence is needed to confirm this.

R assay sclerosis . Studies have shown that treatment with high doses of vitamin B7 can help improve symptoms in people with multiple sclerosis, an autoimmune disease that affects the nervous system and leads to muscle weakness and a range of other problems.

Results published in 2016 showed that biotin is a safe therapy. In some participants, a high dose taken three times a day improved symptoms after 9months of use.

Skin, hair, nails . Statistics say that about 20% of the world’s population suffers from brittle nails. An experiment was conducted in which 35 people with brittle nails received 2.5 mg of biotin per day for 1.5–7 months, after which 67% of the participants had a 25% increase in the thickness of the nail plate and a significant decrease in brittle nails. There is also evidence that vitamin H can improve nail strength and longevity, and improve hair and skin health.

Research published in 2015 showed that women with thinning hair experienced some reduction in shedding after taking an oral marine protein supplement with biotin for 90 days. However, the US Office of Dietary Supplements (ODS) considers there is insufficient evidence that biotin supplements can strengthen nails and promote healthy hair.

In addition to these cases, biotin deficiency can occur in patients on long-term intravenous feeding, in infants who consume breast milk with a low biotin content, in patients with impaired absorption of the vitamin due to inflammatory bowel disease, dysbacteriosis and other disorders of the gastrointestinal tract as well as in smokers and those taking epilepsy medications such as phenobarbital, phenytoin, or carbamazepine.

The effects of long-term deficiency of biotin vitamin may be manifested by the following symptoms:

• increased cholesterol and blood sugar levels;
• general weakness, fatigue, deterioration in general well-being;
• rapid hair loss and alopecia;
• scaly red rash around the eyes, nose, mouth and genitals;
• hallucinations and seizures;
• numbness and tingling sensation in arms and legs;
• loss of control of body movements, known as ataxia;
• immunosuppression;
• frequent bacterial and fungal infections;
• certain types of liver disease.

Skin and hair benefits

Studies show that increasing your biotin intake can improve overall hair quality, including body and shine. Taking biotin supplements also helps for their growth.

Vitamin B7 deficiency is expressed by the following symptoms in relation to hair and skin:

• dull appearance and hair loss;
• poor complexion, dry and flaky skin;
• red rash around eyes, nose, mouth.

“Beauty Vitamin” saturates hair follicles with sulfur, which normalizes the functioning of the sebaceous glands, provides elasticity and silkiness to curls, and effectively fights seborrhea.

The effect of vitamin H on hair is expressed as follows:

• supporting red blood cells, provide hair follicles with oxygen;
• stimulating insulin metabolism, contributes to the saturation of each bulb with glucose;
• maintains the balance of keratin for hair elasticity, and the ability to withstand negative environmental influences.

In order to determine the benefits of vitamin B7 for hair, studies were conducted in which 30 women took biotin for three months, and a second company of the same number took a placebo. The structure of the hair in all women was damaged due to stress, poor diet, hormonal problems, etc. After a course of biotin supplements, there was a noticeable improvement in the condition of the hair in women in the first group, while nothing changed in the placebo group.

Thus, all the studies known today confirm the effectiveness of biotin for hair, which is recommended to be obtained from food or nutritional supplements.

Hair and skin additives

Biotin preparations

Biotin 5000 mcg capsule №60

Beauty vitamin Biotin (B7) is responsible for the transport of sulfur atoms into the structure of hair, skin and nails, thus ensuring a healthy appearance of a person. Promotes the formation of keratin, a building block for skin, hair and nails.

B vitamins (Biotin) 5 mg 120 capsules TM Country Life

Affects the metabolism of macronutrients, reduces glucose levels, normalizes the process of hemoglobin synthesis, improves skin condition, strengthens hair and nails, speeds up metabolism.

Biotin 300mcg Tablet #100 Solgar / Solgar®

Supports healthy skin, nails, hair and required for the action of certain enzymes. Stimulates the production of energy in the body, is necessary for the proper metabolism of proteins, carbohydrates and fats.

Benefits for women

As a “beauty vitamin”, coenzyme R is beneficial for women. It improves the structure of the skin, heals the hair and strengthens the nail plate. Sometimes there may be a deficiency of this element during pregnancy and lactation. This is especially true if a woman experiences toxicosis of pregnant women, in which all vitamins are absorbed very poorly. However, in order not to harm the fetus, the additional intake of biotin supplements during pregnancy must be agreed with the doctor.

Vitamins with biotin for women helps to maintain normal weight, as it takes part in the breakdown of fats. In addition, it maintains stable blood sugar levels, which is important during pregnancy and breastfeeding. Sugar also plays an important role in normalizing the emotional state of a woman. It is known that the female body accumulates sugar by about 25% less than the male. A rapid drop in glucose leads to irritability, depression, reduced performance and sleep problems.

Deficiency in children

Congenital deficiency of the biotinidase enzyme is quite rare, affecting only one in 20-40,000 newborns and is detected by special screening.

Testing is indicated for symptoms such as seizures, hearing and vision loss, skin problems, hair loss or absence (alopecia), and frequent infections. Usually, the diagnosis is made between the ages of 1 and 6 months. The appointment of biotin preparations brings everything back to normal, however, in order to prevent mental retardation, treatment should be started as early as possible. Late therapy may resolve skin and hair problems, but may not affect neurological changes. Reception of biotin in this case is necessary throughout life. World Health Organization recommends inclusion of biotinidase deficiency test in newborn screening

Biotin in foods

Product name	Biotin content per 100 g	Percentage of daily requirement
Soy (grain)	60 mcg	120%
Egg yolk	56 mcg	112%
Chicken egg	20.2 mcg	40%
Oatmeal	20 mcg	40%
Oat flakes “Hercules”	20 mcg	40%
Peas (shelled)	19.5 mcg	39%
Non-fat milk powder	15.3 mcg	31%
Oats (grain)	15 mcg	30%
Rice (grain)	12 mcg	24%
Wheat (grain, durum)	11. 6 mcg	23%
Barley (grain)	11 mcg	22%
Wheat (grain, soft grade)	10.4 mcg	21%
Wheat groats	10 mcg	20%
Powdered milk 25%	10 mcg	20%
Meat (chicken)	10 mcg	20%
Cod	10 mcg	20%
Meat (broiler chickens)	8.4 mcg	17%
Curd 2%	7.6 mcg	15%
Curd 5%	7.6 mcg	15%
Low-fat cottage cheese	7.6 mcg	15%
Egg white	7 mcg	14%
Corn grits	6.6 mcg	13%
Rye (grain)	6 mcg	12%
Camembert cheese	5. 6 mcg	11%
Green peas (fresh)	5.3 mcg	11%
Curd 18% (fatty)	5.1 mcg	10%
Curd 9% (bold)	5.1 mcg	10%

Nutritionists and physicians recommend getting all vitamins and minerals from natural sources in the most absorbable form. Fortunately, vitamin b7 is found in varying doses in many foods. Otherwise, they can be obtained from vitamin complexes.

Anyone who regularly consumes tomatoes, eggs, spinach, nuts, cauliflower, legumes and organ meats may not be afraid to face a biotin deficiency. However, it must be taken into account that food processing leads to a decrease in the activity and effectiveness of vitamin B7.

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How to take it right

Deficiency of coenzyme R in the body can be replenished in two ways: by eating foods rich in this compound, and by taking special biotin supplements. Consider the cumulative effect of receiving a connection. Taking the supplement daily, noticeable improvements occur around the 60th to 90th day from the start of the intake.

Vitamin H preparations available without a prescription. They very rarely cause side effects, which are expressed by nausea, diarrhea, stomach cramps. Before buying, you should consult a doctor who will inform you about potential risks, give advice on choosing a manufacturer brand and doses.

Be aware that biotin supplements can interact with certain drugs that are broken down by the liver, including clozapine (Closaril), haloperidol (Haldol), olanzapine (Zyprexa), etc.

How much to drink and how to drink

There is no consensus on the daily requirement of the body for vitamin B7. With the right diet, a person receives about 40 mcg of it with food. Additional intake depends on many factors (age, gender, weight, purpose of intake, lifestyle) and ranges from 50 to 300 mcg.

Pregnant and lactating women need a higher dose, but before buying the drug, you should consult your doctor.

Recommended doses depend on age and are:

• up to 3 years: 10-20 mcg,
• from 4 to 6 years: 25 mcg,
• from 6 to 10 years: 30 mcg,

9000 5 from 10 years and for adults: 30 – 100 mcg.

In congenital biotinidase deficiency, the initial dose is 5 to 10 micrograms per day.

Dosage of b7 vitamin for hair health:

• for support in winter or after hair coloring, no more than 1000 mcg per day.
• for dryness and brittleness, to stimulate growth – up to 5000 mgc per day.
• at the first signs of baldness, skin diseases – at least 10,000 mcg per day.

Vitamin b7 is available in the form of capsules and tablets, and less often a course of injections can be prescribed. You need to take (drink) biotin for at least 1 month, for hair treatment – at least 3 months, simultaneously with meals or immediately before meals, drinking plenty of water. It is important to understand that for a visible effect, especially in the treatment of hair, it will take time. In the case of treatment, the duration of the course and dosage should preferably be agreed with the attending physician.

Side effects

Biotin is considered a safe vitamin, it is easily excreted from the body in urine and feces, however, taking it much higher than normal can cause some side effects in the form of rashes and nausea. In order to avoid individual intolerance, it is worth consulting with your doctor before buying dietary supplements.

It is undesirable to combine vitamin B7 intake with anticonvulsants, as they reduce the bioavailability of the coenzyme. If such treatment is necessary, it is worth diluting the medication and biotin for different times.

Contraindications

Consumption of food rich in biotin does not pose a significant threat to the body. Large doses of biotin have no known toxic effects, but certain medications, herbs, and supplements may interact.

Abnormal indicators are low levels of vitamins C and B6, high blood sugar levels, and reduced insulin production.