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Calcium fructopyranose borate side effects. Calcium Fructoborate: A Powerful Supplement for Bone and Heart Health

by alexxlab

What are the benefits of calcium fructoborate for bone and cardiovascular health. How does this unique compound impact inflammation and osteoarthritis. Can calcium fructoborate improve lipid profiles and quality of life in patients with stable angina pectoris. What is the recommended dosage and are there any potential side effects.

Understanding Calcium Fructoborate: A Unique Boron-Based Compound

Calcium fructoborate is a naturally occurring compound found in fruits and vegetables. It’s a complex of calcium, fructose, and boron that has gained attention in recent years for its potential health benefits. This unique formulation allows for enhanced bioavailability of boron, a trace mineral essential for various bodily functions.

The compound was first patented in 1999 by Miljkovic, who recognized its potential as a dietary supplement. Since then, numerous studies have explored its effects on human health, particularly in relation to bone and cardiovascular well-being.

Chemical Structure and Stability

The chemical structure of calcium fructoborate is crucial to its effectiveness. It consists of a boron atom covalently bonded to two fructose molecules, with calcium serving as a stabilizing agent. This unique structure contributes to its stability and bioavailability in the human body.

Thermal analysis studies have shown that calcium fructoborate remains stable at temperatures up to 250°C, indicating its ability to withstand various processing and storage conditions. This stability is essential for maintaining its therapeutic properties in supplement form.

The Role of Boron in Human Nutrition

Boron, the key component of calcium fructoborate, is a trace element that plays a vital role in human health. Although not officially recognized as an essential nutrient, growing evidence suggests its importance in various physiological processes.

  • Bone metabolism and strength
  • Brain function and cognitive performance
  • Hormone regulation, particularly sex hormones
  • Immune system function
  • Antioxidant activity

The World Health Organization (WHO) suggests that an intake of 1-13 mg of boron per day is likely safe for adults. However, the optimal intake for health benefits may vary depending on individual factors and specific health conditions.

Boron Deficiency and Its Consequences

Is boron deficiency common? While severe boron deficiency is rare in developed countries due to varied diets, suboptimal intake may be more widespread than previously thought. Potential consequences of insufficient boron intake include:

  • Impaired bone health and increased risk of osteoporosis
  • Decreased cognitive function
  • Altered calcium metabolism
  • Reduced immune function

Calcium fructoborate supplementation may help address these issues by providing a highly bioavailable form of boron.

Calcium Fructoborate and Bone Health: Strengthening Our Skeletal Foundation

One of the most promising applications of calcium fructoborate is in the realm of bone health. Several studies have investigated its potential to alleviate symptoms of osteoarthritis and improve overall bone metabolism.

Impact on Osteoarthritis Symptoms

A double-blind, placebo-controlled study by Reyes-Izquierdo et al. (2012) examined the effects of short-term calcium fructoborate intake on knee osteoarthritis symptoms. The results were encouraging:

  • Significant improvement in WOMAC and McGill scores, indicating reduced pain and improved joint function
  • Beneficial modulation of biomarkers associated with knee osteoarthritis
  • Noticeable effects within 14 days of supplementation

These findings suggest that calcium fructoborate could be a valuable adjunct therapy for managing osteoarthritis symptoms.

Mechanisms of Action in Bone Health

How does calcium fructoborate contribute to bone health? The compound’s effects on bone metabolism are multifaceted:

  1. Enhanced calcium absorption and utilization
  2. Modulation of bone-specific proteins and enzymes
  3. Reduction of inflammatory markers associated with bone degradation
  4. Potential stimulation of osteoblast activity (bone-forming cells)

These mechanisms collectively contribute to improved bone density, strength, and overall skeletal health.

Cardiovascular Benefits: Protecting the Heart with Calcium Fructoborate

Beyond its effects on bone health, calcium fructoborate has shown promise in supporting cardiovascular well-being. Several studies have explored its impact on various markers of heart health and cardiovascular risk factors.

Lipid Profile Improvement

A study by Militaru et al. (2013) investigated the effects of calcium fructoborate supplementation in subjects with stable angina pectoris. The results were impressive:

  • Significant reduction in total cholesterol levels
  • Decrease in LDL (bad) cholesterol
  • Lowered triglyceride levels

These changes in lipid profiles suggest that calcium fructoborate may help reduce the risk of atherosclerosis and other cardiovascular diseases.

Anti-Inflammatory Effects

Inflammation plays a crucial role in the development and progression of cardiovascular disease. Calcium fructoborate has demonstrated potent anti-inflammatory properties:

  • Reduction in C-reactive protein (CRP), a key marker of systemic inflammation
  • Lowered levels of pro-inflammatory cytokines such as IL-1β and IL-6
  • Decreased monocyte chemoattractant protein-1 (MCP-1), involved in the early stages of atherosclerosis

These anti-inflammatory effects may contribute to the overall cardiovascular benefits of calcium fructoborate supplementation.

Quality of Life Improvements: Beyond Physical Health

The benefits of calcium fructoborate extend beyond measurable physiological parameters. Studies have reported significant improvements in quality of life for individuals supplementing with this compound.

Pain Reduction and Mobility

For individuals suffering from osteoarthritis or other joint-related issues, calcium fructoborate supplementation has been associated with:

  • Reduced joint pain and stiffness
  • Improved mobility and range of motion
  • Enhanced ability to perform daily activities

These improvements can have a profound impact on overall quality of life, allowing individuals to maintain independence and engage in activities they enjoy.

Cardiovascular-Related Quality of Life

In patients with stable angina pectoris, calcium fructoborate supplementation has been linked to:

  • Reduced frequency and severity of angina attacks
  • Improved exercise tolerance
  • Enhanced overall well-being and reduced anxiety related to heart health

These quality of life improvements highlight the potential of calcium fructoborate as a holistic approach to health management.

Dosage and Safety: Optimizing the Benefits of Calcium Fructoborate

As with any dietary supplement, it’s crucial to consider appropriate dosage and potential safety concerns when using calcium fructoborate.

Recommended Dosage

What is the optimal dosage of calcium fructoborate? Clinical studies have used various dosages, typically ranging from 108 mg to 216 mg per day. The specific dosage may depend on factors such as:

  • The individual’s age and overall health status
  • The targeted health condition (e.g., osteoarthritis vs. cardiovascular support)
  • Body weight and metabolism

It’s always advisable to consult with a healthcare professional before starting any new supplement regimen to determine the most appropriate dosage for your individual needs.

Safety Profile and Potential Side Effects

Calcium fructoborate has demonstrated a favorable safety profile in clinical studies. However, as with any supplement, there are potential considerations:

  • Mild gastrointestinal discomfort in some individuals (typically resolving with continued use)
  • Possible interactions with certain medications, particularly those affecting calcium metabolism
  • Theoretical concerns about excessive boron intake, although this is unlikely at recommended dosages

Long-term safety studies are ongoing, but current evidence suggests that calcium fructoborate is well-tolerated when used as directed.

Future Directions: Expanding the Potential of Calcium Fructoborate

While the current body of research on calcium fructoborate is promising, there are exciting avenues for future investigation and potential applications.

Emerging Areas of Research

Scientists are exploring additional health benefits of calcium fructoborate, including:

  • Potential anti-cancer properties, particularly in prostate cancer prevention
  • Effects on cognitive function and brain health
  • Role in supporting immune system function
  • Possible applications in sports nutrition and exercise recovery

These areas of research may open up new possibilities for the therapeutic use of calcium fructoborate in the future.

Combination Therapies and Synergistic Effects

Researchers are also investigating the potential synergistic effects of combining calcium fructoborate with other nutrients or compounds. For example:

  • Calcium fructoborate and vitamin D for enhanced bone health
  • Combinations with omega-3 fatty acids for comprehensive cardiovascular support
  • Potential synergies with antioxidants for overall health and longevity

These combination approaches may lead to more targeted and effective supplementation strategies in the future.

As research continues to unfold, calcium fructoborate stands out as a promising compound with wide-ranging health benefits. From supporting bone and joint health to promoting cardiovascular well-being, this unique boron-based supplement offers a natural approach to addressing common health concerns. While more studies are needed to fully elucidate its mechanisms of action and long-term effects, the current evidence suggests that calcium fructoborate may play an important role in maintaining overall health and improving quality of life for many individuals.

Calcium Fructoborate for Bone and Cardiovascular Health

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10 Unforgivable Sins Of Nitra Flex Gat – Nationwide University Network in Indonesia Website

In this Gat Nitraflex overview, we’ll talk about this pre-exercise complement and see if it’s actually value your time and arduous-earned money. The world of dietary supplements can in some ways be likened to the Wild West… not solely lawless, however nonetheless ripe for exploitation and in some situations gat nitraflex a bit bit harmful. Pre-exercises tackle the outlaw role pretty seamlessly, consistently blurring the line between effective coaching assist and probably harmful drug.

Since this can be a stimulant based mostly pre exercise powder it comes with a list of potential unwanted side effects. These uncomfortable side effects are rare – and you need to assess your tolerance to this product slowly. Irregular heartbeat, dizziness, and fast coronary heart fee are essentially the most critical unintended effects related to a very strong stimulant based mostly pre workout. Tingling of the pores and skin may happen when taking GAT Nitraflex.

In NitraFlex, there is a special patented form of the mineral boron generally known as: Calcium fructopyranose borate ( 1 ). Primarily, this is boron on a fancy transport vector. A number of scientific research have found boron to raise testosterone ranges in males. That is why we see different pre workouts like Pre Sequence BULK include it… Although this special form may use some more analysis ( 2 ).

The product is appropriate to be used throughout training days and non-coaching days. It’s endorsed to begin off with a half a scoop of the powder with 236ml of water. On the second day depending in your tolerance degree you’ll be able to improve the dosage to its full one scoop in 236ml of water, 30 minutes previous to work out.

While a monumental dosing of caffeine goes some solution to rescuing Nitraflex, it comes crashing again right down to earth pretty shortly with a pathetic dose of one of the vital exciting dietary supplements available on the market in beta alanine. And don’t even get us began on wasting area in a scoop with ingredient which have subsequent to no scientific analysis to support their inclusion.

GAT Sport Nitraflex attaches specific significance to the excessive citrulline: arginine ratio. This prevents an excessive amount of arginase from being produced: an enzyme that breaks down arginine. Arginine, nonetheless, is necessary for the nitric oxide (NO) degree within the physique and promotes the effectiveness of the pre-workout supplement. One other essential ingredient of Nitraflex is Calcium Fructopyranose Borate (CFB). CFB will increase complete testosterone levels in addition to free testosterone levels within the physique. The non-essential amino acid beta-alanine ensures that the dipeptide L-carnosine stage, particularly in the nervous and muscle tissue, is raised in your body. This in flip results in a rise in athletic performance. GAT Sport Nitraflex is free of creatine. It is intentionally omitted on this ingredient, in order that no water is saved within the physique. Accordingly, Nitraflex is particularly effectively fitted to building lean muscle mass and is right for competition preparations.

Coaching days: Day 1: Start by assessing your tolerance with half a serving of GAT Nitraflex blended with 6oz of cold water. Days 2 and past: Relying on tolerance, mix 1 serving (1 scoop) of NITRAFLEX® with 10oz of chilly water and eat inside 30 minutes before working out.

When merchandise carry a really high caffeine content material it could possibly result in a severe crash a pair hours after utilizing it. In the case of this complement, most don’t undergo from any form of crash. They simply expertise a gradual decline of vitality as time passes by. It is very important note in case you are not a caffeine drinker or you might be quite sensitive to caffeine it’s possible you’ll very effectively experience a crash after using this product. To avoid this it would be best to cut back the serving dimension to start out with till you get adjusted to consuming merchandise with caffeine. Overall, you need to modify to it fairly simply after which you should have no worries a couple of mid-afternoon crash.

You should purchase Nitraflex from the official GAT Sport website, where it is obtainable in a range of flavors and bulk choices. Nitraflex can be available from quite a few on-line retailers, together with Amazon and eBay, though there is a possibility that you will encounter a counterfeit product there.

Introducing Root Aspects For Gat Nitraflex

GAT fans can now purchase the model’s all-new weight reduction infused pre-exercise via the web retailer on its website Instantly from GAT, Nitraflex Burn will currently value you $forty six. 99 for a full-dimension, 30 serving tub with two tastes to choose from in Pink Lemonade and Blue Raspberry.

Immediate Advice For Gat Nitraflex – What\’s Needed

Enlarge energy, power, focus, stamina and restoration with a group of properly researched elements comparable to beta alanine, caffeine and theanine simply to name just a few. Together, these elements assist to reinforce a number of facets of training and efficiency so you a total noob may achieve a nicely rounded improvement in your positive aspects. It doesn’t matter what kind of exercise you are doing, whether or not it’s strength intensive, endurance intensive, power dominant or hypertrophy centered, NitraFlex’s formulation helps you to tackle each with the best stage of intensity each time.

Borat, but not the hero of the film – Science

  • The science

Russian chemists proposed a simple and economical method for obtaining calcium borate with a given shape and size, which is widely used as additives in the production of ceramic foam, pigments and glasses. Scientists from the Institute of General and Inorganic Chemistry im. N. S. Kurnakov (IGIC) RAS and Lomonosov Moscow State University.

Photo: Artem Krasnov, Kommersant

Photo: Artem Krasnov, Kommersant

Calcium borate is a colorless crystal, the calcium salt of boric acid, used to produce a wide variety of materials, such as the ceramic and glass industries. For example, they are added when creating glasses, ceramics and chemical glassware. The addition of this compound to mixtures leads to an increase in the brightness of their color, and such products are “hardened” at lower temperatures than usual.

In the production of glass and fiberglass, calcium borate additives can not only lower the melting point, but also improve the quality of glass: increase mechanical strength, chemical resistance, resistance to thermal shocks, and improve optical properties. However, for its use in industrial materials, it is necessary that the calcium borate powder consists of particles of a given shape and size. This requires the creation of appropriate production technologies. According to the Ministry of Education and Science of Russia, a team of scientists from the IGIC RAS ​​and Moscow State University managed not only to solve this problem, but also to reduce the temperature of calcium borate synthesis.

According to Irina Kozerozhets, Senior Researcher at the Laboratory of Semiconductor and Dielectric Materials of the IGIC RAS, Ph.D. This task can also be achieved by using autoclave equipment. In fact, an autoclave is an industrial “pressure cooker” in which, under the influence of temperature and pressure, some substances are converted into others.

“By varying the processing conditions, it is possible to obtain materials with desired properties that are in demand in modern industry. To obtain calcium borate powders with a strictly controlled particle size, we for the first time used calcium oxide (CaO) nanopowder synthesized by burning a concentrated water-carbohydrate solution of a calcium salt. Further processing of CaO nanopowder in a solution of boric acid at temperatures of 170–200 degrees Celsius for 12 hours made it possible to obtain calcium borate particles of almost the same shape and size. The synthesis was carried out in an autoclave, since under normal conditions the reaction proceeds very slowly,” said Irina Kozerozhets.

The technology can also be used to obtain other important compounds belonging to the class of borates. For example, zinc borate is used as flame retardants (it is added to materials of organic origin to provide fire protection) in the production of plastics, potassium and strontium borates are components of ceramic tile glazes, etc.

In the future, scientists plan to determine the optimal parameters for the synthesis of borates zinc. Several industrial companies have already shown interest in this study.

The work was supported by the Ministry of Education and Science of the Russian Federation within the framework of the state task of the IGIC RAS.
Prepared based on the materials of IGIC RAS ​​

Scientific article published in Ceramics International

An economical method for the production of calcium borate has been developed to optimize the production of industrial materials

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Scientists from the Institute of General and Inorganic Chemistry. N.S. Kurnakov RAS and Moscow State University. M.V. Lomonosov developed a simple and economical method for the production of calcium borate, which is widely used as additives in the production of ceramic foam, pigments and glasses. The results of the study are published in the journal Ceramics International.

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Calcium borate, which is the calcium salt of boric acid, is used in various industries, such as ceramics, enamels, glass. The use of this compound leads to a decrease in the firing temperature of ceramic pigments and an increase in the brightness of their color. In the production of glass and fiberglass, calcium borate additives can not only reduce the melting point, but also improve the quality of glass (increase mechanical strength, chemical resistance, thermal shock resistance, improve optical properties).

Industrial applications require calcium borate powder to be of the right shape and size. This requires the creation of appropriate production technologies. A team of scientists from IGIC RAS ​​and Moscow State University. M.V. Lomonosov succeeded not only in solving this problem, but also in lowering the temperature of calcium borate synthesis.

“Modern chemical industry is focused on the development of simple and efficient technological schemes for the synthesis of powdered materials with a given granulometry, phase composition and purity. This task can be achieved, among other things, using widely used autoclave equipment. In fact, an autoclave is an industrial “pressure cooker” in which, under the influence of temperature and pressure, some substances are transformed into others.