Can i take zinc and vitamin c together: A combination of high-dose vitamin C plus zinc for the common cold
Cleveland Clinic Study Reveals Zinc and Vitamin C Not Effective Treatments for COVID-19 – Cleveland Clinic Newsroom
Cleveland Clinic researchers have found that zinc or ascorbic acid (vitamin C) – or a combination of the two – do not significantly decrease the severity or duration of symptoms in COVID-19-positive patients, when compared to standard care. The study was published today in JAMA Open Network.
Since the start of the COVID-19 pandemic there has been widespread speculation about the role of various vitamins and supplements to prevent or treat it, but there remains limited scientific evidence. Zinc is known to be important for immune function. It also has a role in antibody and white blood cell production and can fight infections. Vitamin C, an antioxidant, can help reduce damage to cells, and has shown to be immune-boosting.
The COVIDAtoZ clinical trial enrolled 214 adult patients with a confirmed COVID-19 infection. Patients were randomized and either received 10 days of zinc gluconate (50 mg), vitamin C (8000 mg), both agents, or standard of care from April 2020 to October 2020. The study was stopped for futility, with no significant difference among the four groups. Specifically the endpoint of a 50% reduction in symptoms showed no significant difference between the usual care, vitamin C, zinc gluconate or the group receiving both vitamin C and zinc gluconate.
“When we began this trial, there was no research to support supplemental therapy for the prevention or treatment of patients with COVID-19,” said Milind Desai, M.D., MBA, director, clinical operations in Cleveland Clinic’s Heart Vascular & Thoracic Institute and co-principal investigator of the study. “As we watched the pandemic spread across the globe, infecting and killing millions, the medical community and consumers alike scrambled to try supplements that they believed could possibly prevent infection, or ease COVID-19 symptoms, but the research is just now catching up. While vitamin C and zinc proved ineffective as a treatment when clinically compared to standard care, the study of other therapeutics continues. ”
The patients enrolled in this study were not hospitalized, but rather managed on an outpatient basis. “We know that not all patients with COVID-19 require hospital admission, and compared to those being treated in a hospital setting, they are more likely to be seeking out supplements that could help them, so it was an important population to study,” said Suma Thomas, M.D., MBA, vice-chairman of strategic operations in Cleveland Clinic’s Heart Vascular & Thoracic Institute and co-principal investigator of the study.
A total of four safety events were observed during the trial, including 3 deaths, however the data safety monitoring board did not believe that any of the adverse events were caused by individual treatments that patients received as a part of the study.
There are steps people can take to reduce the risk of infection. When possible, get a COVID-19 vaccine. Continue to socially distance, wash your hands often, and wear a mask in public.
Zinc, Vitamin C supplements do not help Covid patients recover, says study
A woman undergoes a Covid-19 test | Representational image | Photo: ANI
New Delhi: Vitamin C and zinc supplements do not help Covid-19 patients recover from their illness, a new study published in the journal JAMA Network Open has found.
Zinc and Vitamin C are commonly available, over-the-counter supplements that patients across the world take for the treatment of viral illnesses.
Zinc is thought to aid the cells’ ability to fight off infection, and Vitamin C is an antioxidant that may play a role in immune response.
Sales of both Vitamin C and zinc supplements in India significantly shot up during the pandemic, since both are marketed as immunity boosters.
Limited evidence suggests that high doses of Vitamin C and zinc may reduce duration of common cold symptoms and decrease the severity of symptoms.
Until now, the role of zinc and Vitamin C in decreasing symptoms and improving recovery in patients diagnosed with SARS-CoV-2 infection was uncertain.
So, a team from Cleveland Clinic in the US sought to determine whether either reduces the severity or duration of symptoms associated with SARS-CoV-2 compared with usual care.
For the study conducted from April to October 2020, researchers assessed how 214 adults with confirmed Covid-19 infection responded to 10 days of zinc supplements, 10 days of vitamin C, both, or usual care.
There was no significant difference among the four groups in reduction of Covid symptoms.
Patients who received usual care without supplementation achieved a 50 per cent reduction in symptoms after about 6.7 days compared with 5.5 days for the Vitamin C group, 5.9 days for the zinc group, and 5.5 days for the group receiving both.
There was no reduction in hospitalisations or deaths among the groups.
‘Research now catching up’
“When we began this trial, there was no research to support supplemental therapy for the prevention or treatment of patients with Covid-19,” Milind Desai, director of clinical operations at Cleveland Clinic’s Heart, Vascular & Thoracic Institute, said in a statement.
“As we watched the pandemic spread across the globe, infecting and killing millions, the medical community and consumers alike scrambled to try supplements that they believed could possibly prevent infection, or ease COVID-19 symptoms, but the research is just now catching up,” Desai said.
“We know that not all patients with Covid-19 require hospital admission, and compared to those being treated in a hospital setting, they are more likely to be seeking out supplements that could help them, so it was an important population to study,” said study co-author Suma Thomas, vice chair of strategic operations at the institute.
Also read: Why 50% Indians will be happy to have some Neanderthal DNA. Hint: It has to do with Covid
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Vitamin C & Zinc: Can Supplements Really Boost Your Immune System?
Supplements And Immunity: Facts vs Fiction
Most people have been told at least once to take vitamin C to speed up recovery after catching a cold or the flu. But do supplements help boost immunity? And if so, which supplements should people prioritize? This article takes a look at a few of the most popular recommendations for immunity-boosting supplements and highlights the truth behind the claims.
Vitamin C and colds?
Hands down, vitamin C is one of the most popular supplements promoted as a preventative measure for the common cold. According to experts, little evidence exists to support the theory that vitamin C can prevent respiratory illnesses, including colds. But studies have shown that taking the vitamin can help with shortening colds. Reviewing data from the studies showed that colds could be reduced anywhere from 8-14% in adults and children. But the caveat is people must take vitamin C consistently, not just during an illness.
The lesser-known vitamin D
Vitamin C may get all the attention, but the real MVP is vitamin D. There are plenty of studies that show that vitamin D can reduce a person’s risk of catching a cold or the flu. Known as the sunshine vitamin, many people can get the supplement by simply going outside on a sunny day. But since many people don’t spend enough time outside, a supplement is a good idea if daily diets don’t include foods rich in vitamin D. Along with helping reduce the risk of catching the flu, vitamin D also reduces the risk of multiple sclerosis and developing heart disease. Added benefits include boosting weight loss and reducing depression symptoms.
Zinc for reducing cold durations
Zinc is another popular option that many people recommend when trying to shorten the duration of a cold. While the mineral can’t prevent colds, evidence supports the claim that zinc shortens colds. According to one study, colds were shortened by 30-40% in people who took zinc lozenges. However, people thinking about adding zinc to their cold recovery plan should look for supplements or lozenges that contain at least 80-100mg of zinc. And for best results, try to take zinc within the first 24 hours of experiencing cold symptoms.
What about probiotics?
Most people associate probiotics with regulating the gut. But since the gut contains helpful bacteria, adding a quality probiotic isn’t a bad idea. However, research into whether taking a probiotic can prevent a respiratory infection is mixed. Still, a probiotic can help to shorten a cold. People considering adding the supplement should focus on options that include Lactobacillus rhamnosus or Bifidobacterium animalis lactis since both strains have been proven to reduce symptoms and to block the body’s inflammatory response.
Practice healthy habits
While supplements are a great option to help boost the body’s immunity response, most experts agree that the best way to support immunity is by eating a healthy diet, exercising, and getting plenty of rest. Likewise, people considering taking a vitamin or mineral supplement should speak with a physician first, especially if a person is taking prescription medications or has underlying conditions.
The effectiveness of vitamins C and D against COVID-19
By: Rick Ansorge, UCHealth
As the world watches as the United Kingdom rolls out a mass vaccination program for COVID-19, experts caution that everyone must continue to religiously practice personal protective measures through at least the end of 2021.
The best evidence continues to support these three basic personal practices: mask-wearing, maintaining a physical distance of at least six feet from other people, and frequent hand washing.
A healthy lifestyle is also key to reducing your risk of contracting COVID-19 or developing serious complications if you do.
Staying healthy will help the body fight any virus. Source: Getty Images.
“People need to be doing things like regular and healthy eating, regular and healthy exercise, and regular and healthy stress management,” said Dr. Ian Tullberg, medical director of UCHealth Urgent Care locations throughout Colorado. “If we’re healthy, our bodies are better adapted to handle microbial insults than if we’re overweight and overly stressed.”
Beyond these common-sense measures, what else can people do to decrease their risk of falling prey to a pandemic that shows no signs of abating? Some preliminary evidence suggests that certain common dietary supplements may help.
Dr. Ian Tullberg
One of the most promising of these is the mineral zinc. “There’s some evidence in the medical literature that zinc has been helpful in terms of not curing a viral infection, obviously, but in helping with some of the symptoms of common cold viruses,” Tullberg said. “One of them is a coronavirus.”
COVID-19 is commonly referred to as a “novel” coronavirus, meaning new.
“So if you look at how zinc works in one coronavirus, it most likely is going to be somewhat beneficial,” Tullberg added. “So I would recommend taking it as a supplement of choice to help out with your (COVID-19) symptoms. ”
Zinc lozenges and pills are the best choice. “You want to be careful how you take it,” Tullberg said. “You do not want to take it intra-nasally. You want to take lozenges.”
Cold-EEZE – for example – is a popular lozenge that has been shown to shorten the duration of the common cold. So far, it has not been specifically studied as a treatment for COVID-19 patients.
Each lozenge contains 13.3 mg of zinc. The manufacturer recommends dissolving (not chewing) a lozenge in the mouth every 2-4 hours until symptoms subside. For adults, the recommended daily dose is six lozenges. For children ages 12-17, the recommended daily dose is four lozenges.
Researchers don’t know if zinc lozenges and pills can help healthy people avoid a COVID-19 infection. “There isn’t anything showing there’s any kind of prophylaxis from taking it,” Tullberg said. “But is it going to hurt you? No, so if you want to take it, please do.’’
Zinc is an integral part of some very preliminary prophylactic regimens developed by some healthcare organizations. These include the Eastern Virginia Medical School (EVMS), which recommends a daily zinc dose of 75 mg-100mg.
EVMS also recommends daily doses of vitamin D3 (1,000-4,000 IU), vitamin C (500 mg), and melatonin (0.3mg-2 mg each night). The school also recommends twice-daily doses of quercetin (250 mg-500 mg) and says that a daily dose of famotidine (Pepcid) of 20-40 mg may be added to the mix.
Tullberg is dubious that such measures are necessary, especially in healthy people who already have normal levels of nutrients such as vitamin D3 and vitamin C.
“Taking extra amounts of those vitamins is not really going to be beneficial unless you’re already deficient in those things,” he said.
Vitamin D is known as the sunshine vitamin but it can also be found in some foods, such as in some fish and in egg yolks. Those deficient in Vitamin D may struggle more to fight COVID-19, according to some research. Source: iStock.
Vitamin D deficiency is common in the United States, especially among Hispanic and Black people. These two groups are significantly more likely than other groups to be infected with COVID-19 and to develop serious, even fatal complications.
Severe COVID symptoms are also more common among seniors and people who have obesity or high blood pressure.
Several recent studies have shown that people with low levels of vitamin D are more likely to test positive for the virus than those with normal levels.
For example, more than 80% of 200 COVID-19 patients in a Spanish hospital had vitamin D deficiency, according to one recent study. Men were more likely than women to have low levels, and people with low levels also had raised serum levels of inflammatory markers such a ferritin and D-Dimer.
Other research shows that hospitalized patients with an often-fatal COVID-19 complication – acute respiratory failure – had extremely high rates of vitamin D deficiency.
Many studies point to the beneficial effect of vitamin D on the immune system, especially regarding protection against infections.
In developing their prophylactic COVID-19 protocol, the EVMS researchers noted that U.S. patients with low levels of vitamin D were more likely to be hospitalized. They also observed that nations with low average levels of vitamin D were more likely to experience serious outbreaks and higher mortality rates.
EVMS included vitamin C in their protocol because it’s a potent antioxidant that’s critical to the immune-cell function. They cite a large-scale study of more than 11,000 patients showing that vitamin C reduces the risk of contracting colds. They also cite research showing that vitamin C reduced the symptoms of colds, about 25% of which are caused by other coronaviruses.
EVMS endorsed quercetin because it’s also a potent antioxidant. They cite preliminary research showing the supplement binds to the spike protein in the novel coronavirus, which may inhibit its ability to infect cells.
Although melatonin is best known as a sleep aid, it made the list because it can block inflammation, especially in the lungs. It also reduces the risk of fibrosis, which is one of the most serious COVID-19 complications.
Dehydration puts you at higher risk for any type of viral or bacterial illness, urinary tract infections and pneumonia. Photo: Getty Images.
Although there’s no proof that any of these supplements can combat COVID-19, Tullberg said, there’s one intervention that will definitely make a difference: hydration.
“If you’re dehydrated, you’re at higher risk of any type of viral or bacterial illness, urinary tract infections, and pneumonia. If you have dry mucus members because you’re not drinking enough fluids, that decreases your immune response because it decreases your immune barrier.”
Study finds vitamin C, zinc don’t cut COVID-19 duration but was too short, flawed in design, CRN claims
The Council for Responsible Nutrition was reacting to a study published late last week in JAMA Network Open. The research, dubbed the COVID A to Z Study, was conducted at the Cleveland Clinic.
The goal of the research was to see if high doses of vitamin C (8,000 mg) and zinc gluconate (50 mg) could lessen the length of symptoms experienced by patients diagnosed with COVID-19 infections who had not been hospitalized. The patients were recruited at and treated at the Cleveland Clinic. The goal of the study was to recruit aboutGet subjects.
The patents were divided into four groups: a vitamin C group, a zinc group, one group that received both supplements and a control group that got no supplement intervention.
The main outcome was the self reported duration and severity of symptoms in the intervention groups as compared to the controls. The original plan called for assessment of 4 symptoms: fever/chills, shortness of breath, cough, and fatigue. In July 2020 after an advisory from the Centers of Disease Control the researchers added additional symptoms to the list, including loss of taste and smell, headache and others, to make a total of 12 symptoms. The subjects were followed for 28 days.
Study halted early because of lack of observed effects
The study was one of more than 30 trials that on the effect of vitamin C in relation to COVID-19 that have been underway since late 2020. However, the Cleveland Clinic study was halted after 214 subjects were recruited and observed because the authors concluded no statistically significant symptom duration outcomes were being observed and continuing the research would be futile.
“[B]ased on the current study, these supplements cannot be recommended to reduce symptom morbidity in such patients. High-dose zinc gluconate, ascorbic acid, or both supplements did not reduce SARS-CoV-2 symptoms. Most consumers of ascorbic acid and zinc are taking significantly lower doses of these supplements, so demonstrating that even high-dose ascorbic acid and zinc had no benefit suggests clear lack of efficacy,” the authors concluded.
In addition to the research, the journal also published a commentary on the study.
“Given the widespread public use of supplements, such as zinc and ascorbic acid, for the prevention and treatment of viral infections, we applaud the COVID A to Z Study5 investigators for adding rigorous science by testing their efficacy and challenging popular beliefs. Unfortunately, these 2 supplements failed to live up to their hype,” the commentary concluded.
CRN: Flawed study might nevertheless have yielded positive results if allowed to run course
Steve Mister, president and CEO of CRN, said the study had many shortcomings, not least of which was to assume that a very short term, high dose application would perform like a drug would.
“The study is plagued by a poor, open-label design, insufficient number of participants, substantial differences in the health status of participants by group, and the expectation that essential nutrients should behave like high-powered pharmaceuticals,” he said.
Mister said his organization believes the researchers may have pulled the plug too soon. He noted that the data gathered from less than half of the target subject pool showed a trend toward benefit in the groups that received the vitamin C alone or that took vitamin C along with zinc. The study might have shown a statistically more robust result if allowed to run its full course.
“[P]atients who received vitamin C or vitamin C and zinc achieved a 50% reduction in their symptoms 1.2 days sooner than the standard of care group, however this finding did not achieve statistical significance by the time the study was prematurely terminated for ‘futility’—having enrolled less than half the intended number. If the study had fully enrolled, the differences in outcomes between groups may have reached statistical significance,” he said.
Commentary adds insult to injury
In addition, Mister said it was unfortunate that JAMA sought to pile on with the attendant commentary.
“Even more disturbing is the commentary by Michos and Cainzos-Achiria that cites the study as evidence that ‘rigorous science’ challenges ‘popular beliefs’ and demonstrates how these supplements fail to ‘live up to their hype. ’ Their editorial reads like a conclusion in search of a premise: that dietary supplements should be viewed as a waste of time just waiting for science to disprove their presumed benefits. This kind of misapplication of a poorly conducted study has the potential effect of dissuading other serious researchers from investigating the potential of a wide range of supplements, such as vitamin C, vitamin D, zinc, melatonin and others, for their ability to support immune function and resistance to respiratory infections, including COVID-19,” Mister said.
“Fortunately, much of that research is already underway in a range of clinical trials examining the relationship between nutrients and resistance to disease. CRN looks forward to the publication of more research and urges healthcare practitioners and consumers alike to reserve judgment on the effects of nutrients like vitamin C and zinc until more credible science is published,” he concluded.
Source: JAMA Network Open
Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection; The COVID A to Z Randomized Clinical Trial
Authors: Thomas S et al.
Source: JAMA Netork Open
Supplements for the Treatment of Mild COVID-19—Challenging Health Beliefs With Science From A to Z
Authors: Michos ED, Cainzos-Achirica M
Vitamin C, Vitamin D and Zinc Could Help Fight Covid-19
Many nutrients and elements influence the resilience of the human immune system. Among these, vitamin C, vitamin D and zinc stand out as some of the most important, with immunomodulatory functions as well as a role in maintaining epithelial and endothelial barriers, including lung tissue. With the Covid-19 pandemic currently showing no signs of abating, there has been much speculation about whether they could play a role in both the prevention and treatment of the virus.
Around the world, multiple studies are now ongoing to determine whether supplements of common nutrients and vitamins could help ward off infections of SARS-CoV-2, the coronavirus that causes Covid-19 or even treat the disease by limiting its inflammatory effect on the lungs and other organs. What is clear is that the greatest benefit of supplements is likely for people who suffer from specific nutrient deficiencies.
Despite its name, vitamin D is actually a hormone produced within the body which regulates over 200 genes in different cell types. Vitamin D is known to help keep bones strong and enhances the functionality of immune cells. Vitamin D may also help control inflammatory responses generated by Covid-19 by downregulating pro-inflammatory cytokines. The high mortality rate and long-term symptoms of Covid-19 are associated with so-called “cytokine storms”, which are caused by an overreaction of the body’s immune system.
Preliminary data from patients with Covid-19 suggests a relationship between vitamin D deficiency and the severity of cytokine storms, indicated by high serum levels of C-reactive protein (CRP), which rises when there is inflammation in the body. A study published in May 2020 found a link between low levels of vitamin D and higher percentages of Covid-19 cases and mortality in Europe, while a study published in September 2020 reported that hospitalized Covid-19 patients who had sufficient levels of vitamin D showed less severe symptoms and lower mortality. Boston University School of Medicine’s Dr. Michael Holick, senior author of the second study, explained in a press release:
“Our study provides direct evidence that vitamin D sufficiency can reduce Covid-19 complications, including cytokine storms and ultimately death.”
Vitamin C (or ascorbic acid) is a water-soluble micronutrient with antioxidant properties that maintains the resistance of the epithelial barrier to disease and supports the function of both innate and adaptive immune systems. Research suggests that oral vitamin C may reduce the incidence and duration of respiratory infections, while intravenous vitamin C may reduce mortality and time on mechanical ventilation for severe respiratory infections, including Covid-19.
In early 2020, seven U.S. doctors joined together to promote a treatment for seriously ill Covid-19 patients involving the intravenous combination of vitamin C, corticosteroids and the anticoagulant heparin (called the “MATH+ Protocol“). Dr. Paul Marik, MD, Professor of Internal Medicine and Chief of Pulmonary and Critical Care Medicine at the Eastern Virginia Medical School, conceived of the treatment as a way to mitigate runaway inflammation in the lungs, which is the principal cause of mortality in most Covid-19 patients.
“It’s not the Covid-19 virus that kills patients, it’s their response to it,” said Marik, describing the excessive inflammation that results from an overly aggressive immune system (cytokine storms).
(Credit: Getty Images)
Dr. Marik and his medical partners propose the use of vitamin C and steroids, which both have potent anti-inflammatory properties, to control cytokine storms. While the treatment remains controversial, it is not unconventional—vitamin C has been used widely in the Chinese treatment of Covid-19 patients. Various clinical trials involving vitamin C injections are now ongoing in different countries across the globe.
The Zinc Link
It’s not only vitamins C and D which could play an important role in boosting the body’s defenses against Covid-19 and minimizing damage following infection. Zinc is essential for maintaining a robust immune system, with an important role in the maintenance, development and activation of cells during innate and adaptive immune responses. It also plays a role in the integrity of epithelial barriers, which are essential in order to prevent the entry of pathogens into the body.
Claude Laggard, a French medical biologist and founder of the Nutria Laboratory, is surprised that the link between zinc deficiency and severe Covid-19 symptoms has so far been underexplored and he carried out a study that highlights the role that zinc plays in our immune systems. Laggard said:
“Zinc plays a fundamental role in the body and is involved in multiple biological reactions. Our body doesn’t need a lot of zinc, but since there are numerous food interferences, its presence in optimal concentrations is not guaranteed. Zinc deficiency affects up to a quarter of all people in Western countries and I am convinced that the majority of Covid-19 sufferers are deficient.”
Taking zinc for Covid-19 could be beneficial?(Credit: Ri Butov from Pixabay)
The role of zinc in immune system pathways is complex, since it participates both in pro-inflammatory and regulatory pathways. Zinc deficiencies have been associated with higher IL-6 responses (IL-6 is an interleukin that plays an important role in severe lung damage caused by Covid-19). Zinc also inhibits SARS-Cove RNA polymerase and its ability to replicate. Research presented at the 2020 ESCMID Conference on Coronavirus Disease suggests that lower levels of baseline plasma zinc are associated with poorer survival outcomes in severe Covid-19 patients. The research, which was led by Dr. Roberto Güerri-Fernández, of Barcelona’s Hospital Del Mar, involved a retrospective analysis of Covid-19 patients admitted to a university hospital during the spring of 2020. After adjusting for variables such as age, sex, and severity, each unit increase in the level of zinc in the patient’s blood at the time of admission correlated with a 7% lower risk of dying after admission.
“Lower zinc levels at admission correlate with higher inflammation in the course of infection and poorer outcome,” said a member of the team led by Dr. Güerri-Fernández.
The potential benefits of Vitamin D3, Zinc, Vitamin C and Melatonin supplementation during the COVID-19 pandemic.
Currently, there are no specific CDC guidelines in place for the use of vitamins or supplements for the prevention or treatment of COVID-19. In addition, Vitamins/Supplements/Nutraceuticals are not regulated by the FDA. It is important to obtain products from a reputable company and in a form that is well tolerated and well absorbed. In my opinion, these are simple, safe measures that may ensure an individuals immune system is optimal if they contract COVID-19. Consideration of utilizing supplements should always be combined with a healthy lifestyle including exercise and a whole food based diet.
Recommended Immune Support Protocol
- Vitamin D3 with K2, 5,000iu/daily
*Consider checking your Vitamin D3 level. If <30ng/ml consider 10,000iu/daily for the first two months.
- Zinc picolinate or Zinc glycinate 30mg once or twice daily
*Consider Zinc lozenge (Cold Eeze, Zinc Gluconate) 1-3x daily prior to anticipated public exposure.
- Vitamin C, 1,000mg once or twice daily
- Melatonin 3-5mg daily
Severe acute respiratory syndrome coronavirus-2 (SARS-COV-2, COVID-19) has quickly became a global pandemic and has been responsible for over 200,000 deaths in the United States. Specific risk factors associated with a poor outcome after SARS-COV-2 infection include increased age, obesity, diabetes and underlying cardiorespiratory illness. Although mortality of infected individuals has steadily decreased, there is no current curative treatment and no vaccine is currently available. In many cases, morbidity and mortality are related to the development of an acute inflammatory immune response manifested as a “cytokine” storm, with resulting progressive respiratory compromise and development of Acute Respiratory Distress Syndrome (ARDS). Researchers have realized the importance of reducing the cytokine storm experienced by patients with this potentially life-threatening virus. Members of the medical community are beginning to evaluate the potential role of vitamins and supplements as potential treatment options or as additions to other treatments. (1)
A. Vitamin D3
The first step in the formation of vitamin D occurs in the skin as UVB rays convert 7-dehydrocholesterol to cholecalciferol. Modification occurs first in the liver, producing 25-hydroxyvitamin D3 or Calcidiol. Calcidiol then enters our circulation and is converted by the kidney and other tissues into the active form-1,25 dihydroxyvitamin D3 or Calcitriol. One of the main functions of vitamin D3 is to increase intestinal Calcium, Phosphorous and Magnesium absorption from our food. It acts to regulate proper bone mineralization and prevent osteoporosis. A severe deficiency of vitamin D, resulting in weak and soft bones, is known as “Rickets”.
But vitamin D3 has broad effects beyond its role in bone health. Calcitriol is also formed in other tissues including the brain and respiratory system. Calcitriol produced in those tissues has localized effects, including immune system support. Vitamin D3 has receptors in every cell of our bodies. The effects of Vitamin D3 are most similar to the effects of a hormone. Like other hormones, it has receptors within our cells and is able to bind to DNA and affect gene expression. In this manner it effects the regulation of about 900 different genes.(2)
An analysis of multiple studies evolving vitamin D and respiratory infection demonstrated vitamin D supplementation was safe and protected against respiratory infection, especially in individuals who were the most vitamin D deficient. (3,4)
Vitamin D3 has the ability to reduce inflammation by modulating the cytokine storm from TNF-α (tumor necrosis factor-alpha) and IFN-β (interferon-beta) associated with Influenzae A (h2N1)(5).
A review of current literature related to Vitamin D3 clearly suggests adequate Vitamin D3 levels are protective against severe COVID-19, especially in susceptible populations. It appears a correlation exists between Vitamin D3 levels and COVID-19 susceptibility. Vitamin D3 supplementation could prove to be an essential element in the fight against COVID-19.(6)
Two studies in the initial phase of the COVID-19 pandemic demonstrated that patients with COVID-19 infection have worse outcomes if their vitamin D levels are low. (7,8)
A retrospective study from the Philippines looked at 212 patients infected with COVID-19. The overwhelming majority of patients with severe and critical COVID infection had vitamin D levels <30ng/ml (insufficient) or <20ng/ml (deficient). The study author concluded that Vitamin D supplementation could possibly improve clinical outcomes of patients infected with COVID-19. (7)
A second retrospective study, this one from Indonesia, examined the outcomes in 780 patients infected with COVID 19. In this study, after correcting for age, sex and comorbid conditions, patients with insufficient (21-29ng/ml) Vitamin D levels had a mortality rate 7.6 times higher. In patients with Vitamin D deficiency (<20ng/ml), the mortality rate was 10 times higher. (8)
Although these are retrospective studies, there appears to be a strong correlation between deficient and insufficient vitamin D levels and increased mortality from COVID 19 infection. But, correlation does not necessarily mean causation. Elderly, frail, immunocompromised and metabolically unhealthy individuals tend to be less physically active and spend less time outdoors. As a result, they have lower levels of Vitamin D3.
Increasing vitamin D levels, especially in susceptible populations requires simple, effective measures. According to a 2011 study, over 40% of adults in the US are deficient in Vitamin D (<20ng/ml). This is even higher in populations with increased skin pigmentation including Native Americans, Hispanics and African-Americans. (9)
Recently, a Pilot study looked at the effects of Vitamin D3 supplementation on 76 patients admitted to the Hospital with COVID-19 diagnosis and respiratory symptoms. Fifty(50) patients received high dose vitamin D3 supplementation. Only 1/50 patients (2%) required admission to the Intensive Care Unit. Of the 26 remaining patients who did not receive Vitamin D3, 13/26 (50%) required admission to the Intensive Care Unit.(10)
Researchers have also noted patients with deficient Vitamin D3 status are almost twice as likely to test positive for COVID-19. (11)
How to Raise Vitamin D
- Regular sun exposure is the most natural way to raise vitamin D levels. Aim for 10–30 minutes of midday sunlight, several times per week, without sunscreen. People with pigmented skin may need a little more than this. Your exposure time should depend on how sensitive your skin is to sunlight. Eat whole, nutrient dense foods and avoid processed food. Remember, Vitamin D3 is primarily supplied by sunlight, not food. But our physiological state, including obesity and metabolic syndrome, is related to low Vitamin D3 levels.
- Vitamin D supplementation. To best guide recommendations for supplementation, it may be reasonable to obtain a blood test to determine your vitamin D3 level. Typically, in vitamin D3 deficient patients, I utilize 10,000iu/daily for 1-3 months and then switch to 5,000iu/daily.
Vitamin D3 (cholecalciferol) is recommended over vitamin D2 (ergocalciferol). In my opinion, any vitamin D3 supplement should contain vitamin K2 or Menaquinone. As discussed, vitamin D3 assists in Calcium absorption, vitamin K2 may be necessary to ensure Calcium deposition in bone.
Recommendation: Vitamin D3 with K2, 5,000iu-10,000iu/daily
B. Vitamin C
Overall, regular use of vitamin C supplements shortens the duration of the common cold, but taking vitamin C supplements once cold symptoms have already begun, has no proven benefits. In addition, Vitamin C does not reduce the risk of contracting a cold, except in persons undergoing heavy physical stress (e.g. marathon runners, skiers, or soldiers) where the incidence of colds is cut in half. It is likely that this antiviral effect is why vitamin C has attracted interest as a possible treatment of COVID-19. (12)
A meta-analysis of twelve trials looked at the length of ICU stay and requirement for mechanical ventilation in patients receiving Vitamin C supplementation. Patients receiving Vitamin C supplementation required 8% less time in the ICU. In three trials in which patients needed mechanical ventilation for over 24 hours, vitamin C shortened the duration of mechanical ventilation by 18.2%.(13)
Recommendation: *Liposomal or *Bioperine containing Vitamin C 1,000mg once or twice daily
“Liposomal” drug delivery systems utilize a biocompatible layer of fats, known as phospholipids, to deliver nutrients. They utilize the same phospholipids that are contained in our cell membranes.
“Bioperine” is a patented extract of black pepper that has also been shown to facilitate nutrient absorption.
Zinc supplementation improves the mucociliary clearance of inhaled particulates, strengthens the integrity of the epithelium, decreases viral replication, preserves antiviral immunity, attenuates the risk of hyper-inflammation, supports anti-oxidative effects, reduces lung damage and minimizes secondary infections.(14)
A study comparing Zinc levels in 47 patients infected with COVID-19 with a control group, showed that a significant number of COVID-19 patients were zinc deficient. These Zinc deficient patients experienced more complications including a longer hospital stay and increased mortality. Although it is not clear whether zinc supplementation after admission to hospital with a diagnosis of COVID-19 helps to reduce the severity of disease, a recommendation is made for more research to examine the role of Zinc supplementation as a cost-effective therapy for COVID-19. (15)
Recommendation: Zinc picolinate or Zinc glycinate 30mg once or twice daily
Zinc lozenge (Cold Eeze) prior to anticipated close contact.
It is well-known that melatonin is an anti-oxidative and anti-inflammatory agent that counters acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) induced by viral and bacterial infections. Melatonin can be beneficial in critically ill patients via reducing vessel permeability, inducing sedation, decreasing agitation and increasing sleep quality. These beneficial properties of melatonin may highlight this hypothesis that melatonin may exert further clinical outcomes for COVID-19 patients (16)
Although the direct protective action of melatonin against COVID-19 is unknown, its extensive application in animal studies and human clinical trials has repeatedly verified its efficacy and safety in a broad range of disorders. Therefore, melatonin practical usage in the current COVID-19 outbreak is suggested to be beneficial.(17)
Recommendation: Melatonin 3-5mg daily
If you have any questions, please email me at [email protected] or call Benessere Clinic (332-6222)
Anthony Lowham MD
- Michienzi SM, Badowski ME. Can vitamins and/or supplements provide hope against coronavirus?. Drugs Context. 2020;9:2020-5-7. Published 2020 Jun 22. doi:10.7573/dic.2020-5
- Bivona G, Agnello L, Ciaccio M. The immunological implication of the new vitamin D metabolism.Cent Eur J Immunol. 2018;43(3):331‐ doi:10.5114/ceji.2018.80053
- Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. 2017 Feb 15;356:i6583.
- “Vitamin D Fact Sheet for Health Professionals”. National Institutes of Health (NIH). February 11, 2016
- Khare D, Godbole NM, Pawar SD, Mohan V, Pandey G, Gupta S, Kumar D, Dhole TN, Godbole MM. Calcitriol [1, 25[OH]2 D3] pre- and post-treatment suppresses inflammatory response to influenza A (h2N1) infection in human lung A549 epithelial cells. Eur J Nutr. 2013 Jun;52(4):1405-15. doi: 10.1007/s00394-012-0449-7. Epub 2012 Sep 27. PMID: 23015061.
- Razdan K, Singh K, Singh D. Vitamin D Levels and COVID-19 Susceptibility: Is there any Correlation?.Med Drug Discov. 2020;7:100051. doi:10.1016/j.medidd.2020.100051
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9, 2020). Available at SSRN: https://ssrn.com/abstract=3571484 or http://dx.doi.org/10.2139/ssrn.3571484
- Raharusun, Prabowo and Priambada, Sadiah and Budiarti, Cahni and Agung, Erdie and Budi, Cipta, Patterns of COVID-19 Mortality and Vitamin D: An Indonesian Study (April 26, 2020). Available at SSRN: https://ssrn. com/abstract=3585561 or http://dx.doi.org/10.2139/ssrn.3585561
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- “Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study”
Marta Entrenas Castillo, Luis Manuel Entrenas Costa, José Manuel Vaquero Barrios, Juan Francisco Alcalá Díaz, José López Miranda, Roger Bouillon, José Manuel Quesada Gomez
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Rospotrebnadzor told how to take vitamins correctly
Rospotrebnadzor told how to take vitamins
Rospotrebnadzor told how to take vitamins correctly – RIA Novosti, 03.03. 2020
Rospotrebnadzor told how to take vitamins correctly
Rospotrebnadzor gave recommendations regarding vitamin and mineral supplements to food and told in what cases they can be hazardous to health.About this … RIA Novosti, 03.03.2020
Federal Service for Oversight in the Sphere of Protection consumer rights and human well-being (Rospotrebnadzor)
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MOSCOW, November 6 – RIA Novosti. Rospotrebnadzor gave recommendations regarding vitamin and mineral supplements to food and told in what cases they can be hazardous to health. This was reported on the website of the department. So, it is necessary to take into account the time and circumstances of taking dietary supplements. Both the safety of their use and their effectiveness depend on this. Rospotrebnadzor experts advise taking multivitamins twice a day with meals – half a dose during breakfast and lunch or dinner.You should not drink them on an empty stomach – vitamins of group B and vitamin C in this case can cause painful sensations in the stomach or nausea. And fat-soluble vitamins, which include A, D, E and K, should be consumed with foods that contain a little fat. When taking vitamins and minerals separately, it is necessary to consider their compatibility with each other. For example, zinc combines poorly with calcium and iron. Magnesium should be taken along with calcium. Iron is best taken on an empty stomach, either in the morning or in the afternoon.However, it is poorly absorbed with calcium and vitamin E. Vitamin B12 should also be drunk on an empty stomach, as it is poorly absorbed from the gastrointestinal tract. In addition, before you start taking, you should consult with your doctor if you are using medications for bone loss, cancer, gout, high blood pressure and gastric hypersecretion. fat, omega-3 fatty acids.They are contraindicated for people with seafood allergies, blood clotting disorders and those who take anticoagulants. The more varied and nutritious the diet, the less dietary supplements a person needs, the department stressed. Rational nutrition is the best way to provide the body with all the necessary substances, experts say.
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Society, Federal Service for Supervision of Consumer Rights Protection and Human Welfare (Rospotrebnadzor), vitamins, Russia
MOSCOW, November 6 – RIA Novosti. Rospotrebnadzor gave recommendations on vitamin and mineral supplements to food and told in what cases they can be hazardous to health.This was reported on the website of the department.
So, it is necessary to take into account the time and circumstances of taking dietary supplements. Both the safety of their use and their effectiveness depend on this.
Rospotrebnadzor experts advise taking multivitamins twice a day with meals – half a dose during breakfast and lunch or dinner. You should not drink them on an empty stomach – vitamins of group B and vitamin C in this case can cause painful sensations in the stomach or nausea. And fat-soluble vitamins, which include A, D, E and K, should be consumed with foods that contain a little fat.
When taking vitamins and minerals separately, it is necessary to take into account their compatibility with each other. For example, zinc combines poorly with calcium and iron. Magnesium should be taken along with calcium. Iron is best taken on an empty stomach, either in the morning or in the afternoon. At the same time, it is poorly absorbed with calcium and vitamin E.
July 31, 2019, 18:13In addition, you should consult your doctor before taking any medications for bone loss, cancer, gout, high blood pressure and gastric hypersecretion.
Specialists of Rospotrebnadzor also urged to be careful when taking supplements with polyunsaturated fatty acids, such as krill oil, fish oil, omega-3 fatty acids. They are contraindicated in people with seafood allergies, blood clotting disorders and those taking anticoagulants.
The more varied and nutritious the diet, the less dietary supplements a person needs, the department stressed. Rational nutrition is the best way to provide the body with all the necessary substances, experts say.
April 8, 2019, 14:43We will have breakfast in the mountains, around the beauty of untouched nature, blue sky, dizzy from the clean air. On the table are cottage cheese from the farm, freshly squeezed carrot juice, raspberries, strawberries, tomatoes and cucumbers from the garden, hot bread with pumpkin seeds, tea with mountain herbs on alpine water. How tasty it is, and how much benefit from this food, how many vitamins! But a friend looks at this whole natural holiday with indifference. Instead of breaking off a crunchy roll as soon as possible and spreading apricot jam on it, she takes out a small plastic case with multi-colored pills and begins to swallow one by one.
Exactly ten for breakfast and for dinner – in total, she drinks twelve different drugs throughout the day. All of them, according to her, are vital. She drinks vitamin D and omega-3 for immunity and energy, because everyone in Russia should take them, where for half a year there is a low gray sky and not a ray of sunshine. So said her husband’s nutritionist. She heard about DHEA, a dietary supplement that affects testosterone and estrogen production and prolongs youth, from a friend. Liquid collagen was advised by the wife of an oligarch: according to the latter, her skin became smooth and elastic thanks to him, and not to the plastic surgeon, to whom, according to rumors, she recently flew to America.Beta-alanine and L-carnitine were ordered by the trainer: these drugs are needed for the formation of beautiful muscles and the rapid conversion of fat into energy. She read about glucose optimizer on the Instagram of an American blogger – it supposedly relieves cravings for sweets and starchy foods. On the advice of top model Anna Selezneva, which she shared in Vogue magazine, her friend began to drink magnesium – it helps to fight stress during Fashion Week. And also drops for healthy sleep, pills to stimulate the brain and powder to remove toxins.
I must admit that both Selezneva and my friend look gorgeous. I drink only five drugs: vitamin D and magnesium B 6 , vitamins for hair, spirulina and calcium. Maybe I miss everything in my life?
“Today it is considered bad form not to drink vitamins,” says Elena Romantsova, endocrinologist, nutritionist at the GLMED Longevity and Beauty Residence. – Even if you eat right, calculate proteins and carbohydrates, you cannot replenish the required set of vitamins and microelements, because most products today contain a lot of preservatives, and ecology and stress cause poor absorption of even those vitamins that they contain.In addition, many women in fear of gaining excess weight sharply reduce in their diet foods rich in microelements: bread, cereals, dairy. ”
But at the same time at medical conferences both in Russia and in the West, the problem of polypharmacy is constantly discussed – the excessive intake of medicines, vitamins and dietary supplements. “It is difficult to calculate how a large number of drugs taken simultaneously or on the same day will interact with each other,” says Ekaterina Dudinskaya, Ph.D., endocrinologist at the Russian Gerontological Research and Clinical Center of N.I. Pirogov. – Together they can behave completely unexpectedly: enhance or suppress each other’s action, increase the risks of side effects, generally merge into an unexpected chemical cocktail, the effect of which on the body cannot be controlled. The result may be feeling unwell or an allergic reaction, but worse: such a cocktail can penetrate the cell nucleus and cause damage, provoking serious diseases in the future – diabetes, metabolic disorders and even cancer. Our advice: no more than five to six drugs at the same time. “
Romantsova tells about a patient who came to her clinic with complaints of irritability, heart palpitations and tremors in her hands: “On the advice of a colleague, she drank kelp. A good supplement, only the girl had the first signs of a malfunction of the thyroid gland, and the drug worsened the situation by causing an overdose of iodine. Or here’s the popular omega-3, which is essential for the nervous system and women’s health – polyunsaturated fatty acids in its composition are undesirable for people with poor blood clotting. “
Doctors unanimously say: do not self-medicate; to understand what your body lacks and what it has in excess, consult a nutritionist or endocrinologist. Based on the results of tests for vitamins, minerals and trace elements, as well as familiarity with the circumstances of your life and work, the specialist will prescribe corrective therapy.
The most effective today are monovitamins, they are better absorbed. Take at least twenty minutes between taking each tablet, for example, one before meals, the second between the first and second courses, and after meals.
If there is no acute deficiency, which was revealed by the tests, then the course of taking one drug can be from one to three months – this period is enough for the substance to accumulate in the body, but does not cause any side effects. And doctors recommend taking a biochemical blood test every six months.
Supplements and vitamins are not a panacea, but only a supplement to a healthy lifestyle that includes proper, balanced nutrition, exercise and positive thinking.Only in this case the pills from the yellow suitcase will work, and you will be full of energy, you will have smooth beautiful skin, shiny hair, you will sleep peacefully and stop being nervous about trifles.
- Iron and zinc inhibit the absorption of vitamins, so drink them separately from other preparations and from each other. Preferably one hour or two hours after eating. For example, one pill before breakfast and one before dinner.
- In the morning, to wake up and invigorate, take B vitamins – they also protect brain cells from stress.Calcium is absorbed better in the evening, and magnesium dilates blood vessels, relaxing muscles and improving sleep.
- Vitamins A, D and E are well absorbed during meals, and best of all with fatty foods such as olive oil, salmon, nuts or avocados. But vitamins C and group B should be taken with plenty of water.
Zinc for the body ᐈ Appointment, For men, For women, Application of zinc.
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146. Karamali M, Heidarzadeh Z, Seifati SM, et al. Zinc supplementation and the effects on pregnancy outcomes in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Exp Clin Endocrinol Diabetes. 2016; 124 (1): 28-33. Pubmed
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90,000 MAGNESIUM + VITAMIN B6 »Polski Lek S.A.
Vitamins for adults, Magnesium preparations, Cardiovascular system, Antistress and wellness, For the elderly
Tablets for swallowing
Magnesium + Vitamin B6 is recommended for people who, due to stress or unhealthy diet, are especially vulnerable to magnesium deficiency. Magnesium + Vitamin B6 strengthens
Tablets for swallowing
Magnesium + Vitamin B6 is recommended for people who, due to stress or unhealthy diet, are especially vulnerable to magnesium deficiency. Magnesium + Vitamin B6 strengthens the nervous system, prevents muscle cramps and weakness, and increases resistance to stress. Magnesium contributes to the reduction of tiredness and fatigue, assists in the proper functioning of muscles and helps maintain the structure and function of teeth and bones.
Vitamin B6 contributes to the normal functioning of the nervous system.
Ingredients: magnesium carbonate, fillers: cellulose, sorbitols; anti-caking agent: talc, magnesium salts of fatty acids, polyvinylpyrrolidone; vitamin B6 (pyridoxine hydrochloride).
Content of vitamins and minerals in the recommended daily dose – 1 tablet
(% of the recommended dietary allowance)
The product may contain lactose (from milk).
Swallow the tablet and drink it with water.
Recommended daily dose: 1 tablet a day.
Do not exceed the recommended daily dose.
Food supplements are not a substitute for a varied diet.
90,000 doctor’s answers to 25 important questions
Collagen: is it worth taking?
This is perhaps the most common question.Collagen is a protein that makes up the tissues of the human body. It is responsible for the elasticity of muscles and skin elasticity, strengthens joints and ligaments. The human body produces this essential protein on its own. And then a reasonable question arises: then why take collagen? The fact is that with age, the synthesis of its own collagen slows down. For those who want to delay old age and restore firmness to the body, collagen supplements have been invented.
Do I need to take collagen orally: opinions of doctors
Experts agree that taking collagen by mouth is more effective.The fact is that nutrients are better absorbed through the digestive tract.
Collagen: why do women take it?
Collagen helps to improve not only the condition of the skin, but also the hair and nails. He also fights stretch marks.
How old can you take collagen?
Collagen synthesis begins to decline at the age of 25. Age-related changes are not yet visible, but collagen supplements will be beneficial for those looking to strengthen nails and hair. And from the age of 30 – as a prevention of aging.After 40 years, collagen loss becomes more noticeable. But we can still try to smooth the skin with additives. Do I need to take collagen after 50, because it will no longer relieve wrinkles? Yes, because this protein is responsible not only for the beauty of the face. It is also necessary for the joints – it will help reduce pain that often occurs with age.
Which collagen is better to take – marine or animal?
Animal collagen can be purchased relatively inexpensively – this is the most common type.Marine collagen is more expensive due to the complexity of its production and storage conditions. Both types, when taken orally, are well absorbed. Plant collagen is also isolated, but it would be more correct to call it simply protein.
Which collagen should I take?
Collagen in the form of jelly, collagen in liquid form, collagen in powder form, collagen in pure form … Types of collagen for oral administration are now in stock. A variety of supplements are presented in stores, hydrolyzed collagen (hydrolyzate) is considered the most effective.It is broken down into smaller parts and thus better absorbed. Hydrolyzed does not mean liquid. It is also available in powder form.
Our website contains hydrolyzed collagen in powder form and collagen gel in a sachet. You can choose the type of collagen that suits you and purchase it at the manufacturer’s price.
How to take collagen powder?
The dosages of the drugs are different. But the general principle is simple: a certain amount of powder is diluted with water until dissolved.You can dilute the powder with juice. The main thing is that the liquid is without protein in the composition and not hot. On average, the daily rate of collagen is 2-5 grams per day. For athletes – higher.
Collagen types 1 and 3: how to take?
It’s easy to get confused when choosing collagen. Indeed, in addition to the origin and form, the types of this protein also differ. There are about 30 of them in total. The first three types are the main ones. 1 and 3 are needed to maintain skin elasticity, healthy nails and hair, strong bones. Type 2 – for joints.
Can I take two collagens at the same time?
It is recommended to use type 2 collagen separately from the first two (at least 2 hours apart). A joint reception may not give the desired effect.
How long to take collagen?
These questions are also relevant, because the haphazard intake of any drugs can be harmful. Collagen is taken in courses. They last 2-3 months, then you need to take a break for the same period. For those over 40, the course lasts six months.Then a break for a couple of months.
When is it better to take collagen – in the morning or in the evening? Should you take collagen before or after meals?
We recommend in the morning, strictly on an empty stomach, at least half an hour before meals. So it is better absorbed. If you did not manage to take the supplement in the morning, then you should wait about 4 hours after eating and only then drink collagen.
Collagen: What Should I Take For More Effects?
Collagen’s action will be enhanced by a number of supplements.Among them are vitamin C, hyaluronic acid, magnesium and lecithin, B vitamins.
Collagen and vitamin C – how to take?
Vitamin C is the supplier of amino acids to our body. It is from them that collagen will be synthesized. However, this vitamin is not always enough in the body. Therefore, when taking collagen, it is recommended to also use vitamin C. Without it, collagen is poorly absorbed. Supplements can be found today that contain both vitamin and collagen.
Collagen and Hyaluronic Acid: How to Take Together?
Hyaluronic acid is also responsible for the youthfulness of the skin.When paired with collagen, the effect will be enhanced. The main rule when taking hyaluronic acid is to drink more water.
Can I take glucosamine with collagen?
Sure! Moreover, glucosamine is required for collagen formation. This combination is especially important if there are injuries, tissue damage. Therefore, this complex is often prescribed to athletes.
Collagen and spirulina: can they be taken together?
You can take it together, they will strengthen each other’s action.There are supplements that include both. Spirulina contains B vitamins, which in combination with collagen will help improve hair condition. It is also a source of magnesium and a whole set of trace elements.
Collagen and omega 3: compatibility, how to take?
Hyaluronic acid (collagen type 2) should not be used with fish oil (collagen type 1). This does not mean that something needs to be canceled. We just apply these supplements in different steps, between which several hours must pass.
What should you not take collagen with?
Different types of collagen don’t mix. It also cannot be mixed with hot drinks. When using collagen, it is worth reducing sugar intake, because the latter adversely affects collagen and reduces its absorption.
Is Collagen compatible with breastfeeding?
Pregnancy affects the female body. Often joints begin to hurt, stretch marks appear.Nails after childbirth become brittle, the skin is dry. The body needs to recover. Collagen will help with this. It will also strengthen the bones of mom and baby. Collagen is safe for breastfeeding. However, you should consult your doctor before taking a supplement.
Can collagen be taken for varicose veins?
Collagen is the framework of our vessels. With its lack, the walls of the vessels become inelastic. Their inflammation leads to varicose veins. In the treatment of this disease, a supplement containing collagen is often prescribed.It helps to make the walls of blood vessels and veins stronger.
Can I take collagen for gout?
Yes, supplements are indicated for gout to help strengthen cartilage. This also applies to collagen.
Collagen for joints: how to take?
As mentioned, type 2 collagen is taken for joints. It is the basis of cartilage. Take a supplement as directed by your doctor to prevent diseases such as arthritis or rheumatism.And athletes take collagen to strengthen ligaments and joints, because the load on them increases, and collagen production decreases due to increased physical activity. The dosage for athletes is 10 g of collagen per day.
Can I take collagen for oncology?
Collagen is considered harmless and practically free of side effects. An exception is individual intolerance. But nevertheless, in case of oncological diseases about taking the drug, you need to consult a doctor.
Especially if a stomach tumor is diagnosed.
Collagen for weight loss. Reviews, how to take?
Collagen helps not only improve the condition of nails and hair, but also strengthen joints. It also promotes fat burning and weight loss. Its fibers are better absorbed than other proteins. In addition, collagen induces satiety faster, which means it keeps you from overeating.
Collagen and Protein: How to Take?
Collagen and protein are a popular combination in sports nutrition.They enhance the beneficial properties of each other. And the body gets a double portion of amino acids. Protein is often diluted with milk, but this protein blend cannot be combined with collagen. Therefore, it is better to dilute everything with water.
Who took collagen: reviews
The effectiveness of collagen by mouth is noted by most people who have taken it. According to reviews, joints stop hurting and crunching, it is possible to get rid of dry skin, it becomes more elastic, its color improves, nails become stronger, hair becomes healthy.
Whether or not to add collagen to your diet is up to you and your doctor to decide. We, in turn, can only give the following recommendations. If you do make a positive decision, choose the best quality collagen: with a natural composition and accompanying beneficial substances. Observe the rules for its reception and storage conditions. But the main thing is to have fun with the process. You should be completely satisfied with the taste and smell of the supplement you are taking, only in this case the effect of it will be maximum.
How to survive the period between the first and second vaccinations against COVID-19 – Rossiyskaya Gazeta
Recently, leaflets appeared in Yekaterinburg calling to refuse vaccination against coronavirus. We noticed them at the garbage sites, and these leaflets with dubious information did not cause much excitement. Including because life itself refutes speculation.
Vaccination is gaining momentum in all regions of the Ural Federal District. The number of people vaccinated in the Sverdlovsk region alone at the beginning of March reached 130 thousand people – and not a single serious complication.Another 62 thousand signed up for the procedure. There is confidence in the drug, as well as a desire to know what to expect from a vaccine.
Several RG correspondents, including the author of these lines, have checked on themselves how the vaccination is changing the way of life that has developed over the past year. Initially, there were no problems with the recording: we started early – at the end of 2020, so when the first batch of Sputnik V arrived in the region, invitations followed immediately. Honestly, I was worried, the pressure jumped, so much so that the doctor almost turned back at the preliminary appointment.That is, the therapist examines exactly not for show. They helped me calm down, and pressure worries were the only trouble with the first shot.
Taking a second dose of Sputnik V passed emotionally more calmly, but this time the temperature rose and lasted about a day. The seal in the vaccination certificate that the vaccination was passed helped to treat what was happening in a philosophical way. It is too early to check for antibodies. And, according to experts, there is no need to rush.Why and how is it easier to survive the almost one month period between the first and second vaccinations? We asked the chief epidemiologist of Yekaterinburg, Alexander Kharitonov, about all this.
Alexander Nikolaevich, doctors warn: before vaccination, you should not drink alcohol for three days, after vaccination, take a steam bath. Is it necessary to prepare the body in advance: take immunostimulants, vitamins? After all, stress …
Alexander Kharitonov: There is no need for special preparation.This is a common vaccination, as against any infectious disease. The main thing is that the person at the time of vaccination was healthy, his chronic diseases did not worsen. If there is a tendency to allergic reactions, of course, it is better to consult your doctor.
And my attitude to immunostimulants, to be correct, is not very good. I am sure: immunity must be maintained naturally. A person must eat well, spend a lot of time in the fresh air, get enough sleep, and then the immune system will work.The same goes for vitamins. Nowadays it is fashionable to take vitamin D. There is such an opportunity – take it, and it will not hurt before vaccination. But the same vitamin D is in cod liver, vitamin A – in carrots.
Some healthcare providers say that getting vaccinated in the midst of a pandemic is risky.
Alexander Kharitonov: The danger of getting infected really exists, because COVID-19 is transmitted by airborne droplets and you can catch the virus, especially if you ignore protective measures, at any time.There is more than one known case when people fell ill with coronavirus between the first and second vaccinations. But, as practice has shown, they endured the illness without serious problems. The production of antibodies in the body begins within a week after the first dose.
When does full-fledged immunity to the virus appear? Got a second shot – and free as the wind?
Alexander Kharitonov: No, not free. Only three weeks after the second vaccination is the amount of antibodies necessary for complete protection produced.
Do I need to take a test to confirm?
Alexander Kharitonov: The test is optional. In any case, antibodies will appear at the cellular level. Of course, no vaccine will protect one hundred percent. I repeat: a person who has been vaccinated, even if he gets sick, is not in a severe form, and most importantly, he will not die.
By some sensations it is possible to determine whether antibodies have developed or not? I know people who have very hard endured even the first stage.Young, vigorous …
Alexander Kharitonov: It’s just young people react more sharply to the first stage – the body is fighting. On the second, everything should be fine.
And if there were no complications during the entire period of vaccination, then antibodies will not appear either?
Alexander Kharitonov: This means that everything went well, just the body did not react so violently. For example, neither after the first nor after the second did I record any side effects.Maybe there was a weakness, but I did not notice it, because I worked hard. Nevertheless, antibodies have developed.
I know a person in whom no antibodies were detected even a month after the second stage. They said it might be vaccine resistant. Is this good or bad? And what should he do: be vaccinated with another vaccine?
Alexander Kharitonov: There is no need to rush, let alone inject one more drug. Antibodies may appear later. Again, the question arises about the quality of the test systems used.In the laboratory where you come for the study, be sure to tell them that you carry out the analysis after vaccination and that a quantitative method of determination is needed. In any case, the immune system of the vaccinated person is already ready to face the coronavirus. She will see and react to the penetration of the pathogen.
Are there laboratories in Yekaterinburg where they test for antibodies free of charge?
Alexander Kharitonov: No.
Many are sure that after the vaccination the first days you should stay at home so as not to infect anyone …
Alexander Kharitonov: Nothing of the kind.All Russian coronavirus vaccines are based on a non-living virus. A person who has been injected with such a vaccine cannot be a source of infection. This version probably arose by analogy with the polio vaccine, where a live virus is used and during a certain period, vaccinated and unvaccinated children cannot be found together.
Do I need to notify the manager at work that you are vaccinated?
Alexander Kharitonov: It is not spelled out anywhere that it is necessary to inform the employer.Vaccination is a purely voluntary procedure. In my team, I clearly know who was ill, who was vaccinated, who is going to give the vaccine. I work with doubters. But we will not expel or punish anyone for refusing to vaccinate.
There is a lot of talk now about herd immunity. The virus is said to stop spreading when 70 percent of people acquire antibodies. And in a specific work collective?
Alexander Kharitonov: Herd immunity – when all 100 percent of employees have protective antibodies.It is clear that the teams are different. If ten thousand people work together, then 70 percent will be enough. Well, if a couple dozen, only one hundred percent protection is effective.
Why keep a diary of your well-being on the public services portal after vaccination?
Alexander Kharitonov: To account for rare reactions, possible complications, receive recommendations, and so on. In addition, if you are registered on the portal, the data on the vaccination carried out go to the federal register and after the second vaccination you will receive a certificate with a code that can be printed and provided as a supporting document.Those who do not use the site are marked in the usual vaccination certificate and certified with the seal of the medical institution.
The introduction of special documents – covid passports – is being actively discussed so that they would give greater freedom of movement. In your opinion, is such a document necessary?
Alexander Kharitonov: No. The usual vaccination certificate is sufficient.
How to tune in to vaccination
Anna Tkach, clinical psychologist, head of the advisory and health department of the Yekaterinburg City Center for Medical Prevention:
– First, understand why you need to vaccinate, that is, motivate yourself.Traditional arguments: I want to stop being afraid of getting sick, protect my own health and my loved ones from infection, expand opportunities for visiting cinemas, museums or traveling to other countries.
When you have found the reasons, try to understand what prevents you from getting vaccinated. Most likely, fears will surface, which, if you look closely, have no basis. We do not take into account the contraindications to vaccination, but we consider exclusively anxiety for no apparent reason: fear of fever, complications of chronic diseases.Once you figure out the cause of your fears, try to prevent them. For example, buy medicine in advance to lower your fever.
So, having talked to yourself, you can come to the conclusion that there is no reason to refuse vaccination. And there are myths, information on the Internet that easily throws us off balance. Explore positive experiences, good evidence, and trust yourself.
Five Major Mistakes in Treating Colds
- David Robson
- BBC Future
Photo Credit, Milo McDowell
When we suddenly go from cold to warm weather, we often catch colds.How to protect yourself? And if the nose is already running, what to do?
As it turns out, traditional treatments for the common cold are often based on pseudoscientific beliefs rather than facts. BBC Future has tried to figure out which of these methods actually work and which don’t.
1. Do not take large doses of vitamin C, it is better to replace it with zinc
Photo author, Thinkstock
“Usually the first thing many people start to do with a cold is to take vitamins C and D”, – writes Michael Allan from Canada University of Alberta.
Allan started researching this topic and came to the conclusion that there is practically no benefit from such a “treatment”: for example, marathon runners. But for everyone else, this method reduces the risk by only 3%. An adult has an average cold twice a year. Thus, if you take vitamin C for 15 years, you can avoid only one disease during this period. …”
Lozenges containing zinc have a more positive effect.
Based on three clinical trials, Allan concluded that regularly taking zinc-containing preparations reduces the average annual risk of getting sick by about 1.5 times.
Schoolchildren catch colds from about 6 up to 8 times a year. Based on the data obtained, it was concluded that zinc can accelerate recovery by about one day. But given that preparations containing zinc have a bitter taste and must be taken throughout the year, Allan doubts that he would recommend this remedy.
2. Do not try to completely give up alcohol
Photo by, Unsplash
Perhaps we consider giving up alcohol as a kind of sacrifice for the sake of a healthy lifestyle. It is widely believed that a friendly drinking binge will weaken your immune system and make it more susceptible to viral diseases. However, this issue has not yet been sufficiently studied and experimentally verified. Currently, three independent research groups have concluded that with regular (but moderate!) Alcohol consumption, the risk of catching the common cold is reduced.Much depends, of course, on the drink. For example, drinking wine has a positive effect and drinking beer negative.
However, since this is only preliminary data, it cannot be taken without a grain of salt. But at least you can’t blame the glass of wine you drank the day before for your cold today.
3. Instead of antibiotics, it is better to take antibiotics
Photo author, Thinkstock
Frankly, there is no evidence that antibiotics can help get rid of the common cold.Antibiotics fight bacteria, while the common cold is a viral disease. According to Allan, “taking antibiotics in such cases is more likely to lead to side effects such as diarrhea.”
It is much wiser of you to try to alleviate the symptoms of the disease. A variety of cold pills sold without a prescription in any pharmacy, with a complex effect, can really help a little, but more likely for adults than for children. In addition, the effectiveness of their use is highly dependent on who is taking them, and on the different types of infections, says Michael Allan.
4. Beware of herbal treatments, better take a tablespoon of honey
Photo by Thinkstock
Generally speaking, herbal remedies such as echinacea or garlic tablets do not cure. The only hope is honey.
In three different studies, a spoonful of honey has been shown to help soothe coughs before bedtime much more effectively than various cough syrups. True, such a result was obtained when observing children. In addition, it turned out that the combination of honey and coffee helps to get rid of coughs in adults.How this helps is not yet clear. “But if there’s serious research behind it, it’s worth a try,” Allan said.
5. Do not avoid communication
Photo author, Bruno Nascimento
Communication with loved ones and, in general, people who sympathize with you have a great influence on the process of your recovery. At the very least, they will be able to comfort you even when other remedies are not working.
Patients who are more sympathetic from the doctor overcome the disease faster.This conclusion is based on objective data on changes in the activity of the patient’s immune system.
There are still many unresolved issues that require further research. For example, what is the best way to protect yourself from germs when traveling on a crowded bus: open all windows for proper ventilation, or, conversely, avoid drafts? It is difficult to answer with scientific precision.
According to Allan, the best option is to just stick to common sense: wash your hands regularly and not drink from the same dish with someone who is sick.Of course, this is not a panacea for all diseases, but sometimes the simplest method is the most effective.
Limitation of Liability. All information contained in this article is provided for general information only and should not be considered as an alternative to the advice of your healthcare professional or other healthcare professional.