Nystatin and Triamcinolone: MedlinePlus Drug Information

pronounced as (nye stat’ in) (trye am sin’ oh lone)

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The combination of nystatin and triamcinolone is used to treat fungal skin infections. It relieves itching, inflammation, and pain.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

The combination of nystatin and triamcinolone comes in ointment and cream to be applied to the skin. This medication usually is applied twice a day for no longer than 2 weeks. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use nystatin and triamcinolone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Wash the affected area thoroughly. Apply a small amount of cream or ointment and gently and thoroughly massage it into your skin.

If you use this medication on your face, keep it out of your eyes.

If you are using this medication on a child’s diaper area, do not place tightly fitting diapers or plastic pants on the child. They can increase the absorption of triamcinolone, which can affect the child’s growth.

Before using nystatin and triamcinolone,

• tell your doctor and pharmacist if you are allergic to nystatin, triamcinolone, or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using nystatin and triamcinolone, call your doctor.

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

Nystatin and triamcinolone may cause side effects. If you experience any of the following symptoms, call your doctor immediately:

• acne
• skin sores
• itching
• irritation
• burning
• stinging

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

• Mycolog-II^®¶
• Myco-Triacet II^®¶
• Mykacet^®¶
• Mytrex F^®¶

^¶ This branded product is no longer on the market. Generic alternatives may be available.

Last Revised – 05/15/2019

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Steroid Creams Can Make Ringworm Worse | Fungal Diseases

You should not treat rashes that might be ringworm with creams that contain steroids. Talk to your healthcare provider if you think you might have ringworm or if you have ringworm that is not getting better with antifungal treatment.

Photo credit: Dr. Shyam Verma, India

Do not use steroid creams to treat rashes that may be ringworm

Ringworm is a very common cause of skin rashes. People might have a skin rash that they do not realize is caused by ringworm. For this reason, people sometimes apply over-the-counter creams or ointments containing medications called corticosteroids (or “steroids” for short) to their rash. Steroid creams can be helpful for some skin problems and can even temporarily reduce ringworm symptoms like itching and redness. However, steroid creams don’t kill the fungus that causes ringworm.

Steroid creams can make ringworm worse because they weaken the skin’s defenses. Steroid creams can allow ringworm infections to spread to cover more of the body. Ringworm that has been treated with steroid creams can have an unusual appearance, making it hard for healthcare providers to diagnose. In rare cases, steroid creams can allow the fungus that causes ringworm to invade deeper into the skin and cause a more serious condition.

An emerging international problem

In the United States, over-the-counter steroid creams are not very powerful, which is why they’re called “low potency.” But in some other countries, people can buy creams containing strong steroids without a prescription. Many of these steroid creams also contain antifungal and antibacterial medicines, and the labels say that the cream can be used to treat fungal infections. However, healthcare providers in India report seeing more cases of severe ringworm in people who have used these combination medications.^1-6 These infections have been reported to cover large parts of the body, last for months or longer, and spread to family members.⁴

If you travel internationally, develop a rash, and think it might be ringworm, be aware that strong over-the-counter steroid creams containing combinations of antifungal and antibacterial medicines can make ringworm worse and can cause other health problems. If a healthcare provider in another country recommends a cream for a rash that might be ringworm, ask what medications are in the cream and whether it contains strong steroids.¹

Information for healthcare professionals

Topical corticosteroid use without an antifungal agent is not recommended for ringworm infections (also called “tinea” or “dermatophytosis”). However, patients may have already applied corticosteroids on their own. For example, patients may have applied over-the-counter low-potency topical corticosteroids before seeking medical care. Others may have used higher-potency corticosteroids from:

• A prescription given because ringworm was misdiagnosed as another condition.
• Treatment for an unrelated condition.
• A previous prescription for a different problem.
• Purchase of high-potency steroids abroad.

Use of topical corticosteroids on ringworm can lead to:

• More or larger ringworm lesions.
• Atypical appearance, called tinea incognito, which may involve less erythema (redness), less scale, and indistinct lesion borders. Unusual shapes or patterns can mimic other conditions like atopic dermatitis (eczema).^7,8
• Majocchi’s granuloma, in which the dermatophytes invade deeper than the epidermis (into the dermis or subcutaneous tissue).⁹

These conditions resulting from topical corticosteroid use on ringworm are sometimes referred to as steroid-modified tinea. ¹ Use of topical corticosteroids for ringworm also has led to thinning of the skin, striae (stretch marks), and pigment changes when applied to sensitive regions or through excessive or high-potency corticosteroid use.¹⁰

Combination antifungal and mid-potency corticosteroid creams are available by prescription in the United States. Healthcare providers should be aware that treatment failure has been reported with use of combination therapy for ringworm and the use of certain formulations is not recommended in children.^11,12,15

The overuse of steroids to treat ringworm may contribute to antimicrobial-resistant ringworm infections, an emerging public health concern.

Ringworm in humans

Ringworm is a fungal and highly contagious disease caused by fungi Microsporum, Trichophyton, etc. You can become infected with ringworm only through direct contact with the carrier of the fungus – pets, a person suffering from this disease, household appliances, toys. At the same time, in a person who has become infected from an animal, the process of treating ringworm takes much longer, and the disease itself proceeds in a more severe form. Most often, ringworm in humans affects the scalp and scalp. Much less often, the disease appears on the eyelashes, feet and nails. According to statistics, it is children who most often suffer from this disease and are carriers of the fungus.

– appearance of red spots on human skin. Spots, initially covered with a crust or scales, eventually become covered with tiny bubbles. In places where the spots are localized, there is severe itching;
– the appearance of rounded bald spots in the hair. The hair in these places is very thin and short;
– deterioration of hair health in general;
– thickening and delamination of the nail plate;
– with weak immunity, weakness, headache or fever may occur.

Due to the fact that each organism is individual and reacts to the fungus in completely different ways, there are several forms of ringworm in humans :

1. In the papular-squamous form, lichen appears on the chest or face;
2. In the abortive form, the symptoms of the disease are mild. On the skin, only pale foci of localization of the fungus can be observed, which do not have clear boundaries;
3. When the palms and feet are affected, dry plaques are observed, similar in appearance to ordinary corns;
4. The erythematous-edematous form most often occurs in children. Severe inflammation occurs at the site of the spots. Often this form of the disease is accompanied by allergies;
5. When the form is deep, subcutaneous nodes appear on the legs. As a rule, women get sick with this form of lichen;
6. Microsporic onychomycosis affects the nail plate. The nail is covered with dull spots, becomes brittle and collapses over time;
7. Suppurative-infiltrative form is considered the most severe form of the disease. It is characterized by swollen dense plaques, severe itching and purulent discharge.

To combat ringworm in a person, the doctor prescribes medication to the patient with external and internal antifungal drugs with the active ingredient Ketoconazole , Terbinafine , Clotrimazole , Mikoseptin . For deep lesions of the skin, hair or nails, apply Griseofulvin .

As a rule, with complex and correct treatment, the disease recedes after a few weeks. To prevent the occurrence of repeated plaques, it is recommended to complete the entire course of treatment to the end. Also, the patient is prescribed a special diet, including vegetables, meat, fruits, milk and sour-milk drinks.

The material is for informational purposes only. Medicinal products, biologically active supplements and other products are indicated as an example of their possible use and / or application, which in no way constitutes a recommendation for their use. Before using drugs, dietary supplements and medical equipment and other products, be sure to consult a specialist.

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