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Can you take zinc with vitamin c. Zinc and Vitamin C: A Powerful Combination for Immune Support

Can zinc and vitamin C be taken together. How do zinc and vitamin C support the immune system. What are the recommended dosages for zinc and vitamin C. Are there any side effects of combining zinc and vitamin C. How effective are zinc and vitamin C for fighting colds.

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The Benefits of Combining Zinc and Vitamin C

Zinc and vitamin C are two essential nutrients that play crucial roles in supporting the immune system. When taken together, they can provide a powerful boost to help the body fight off infections and illnesses. But what exactly are the benefits of combining these two supplements?

Zinc helps support immune function, wound healing, and metabolism. It’s involved in hundreds of enzymatic reactions in the body. Vitamin C is a potent antioxidant that aids in collagen production, iron absorption, and immune cell function. Together, they create a synergistic effect:

  • Enhanced immune response
  • Faster wound healing
  • Improved antioxidant protection
  • Better absorption of nutrients

Taking zinc and vitamin C together may be particularly beneficial at the onset of a cold or flu. Some studies suggest this combination could help reduce the duration and severity of symptoms. However, it’s important to note that while these nutrients support immune function, they are not a cure for viral infections.

Recommended Dosages for Zinc and Vitamin C

To reap the benefits of zinc and vitamin C, it’s crucial to take the right amounts. But what are the recommended dosages for these supplements?

For zinc:

  • Women: 8 mg per day
  • Men: 11 mg per day
  • Upper limit: 40 mg per day

For vitamin C:

  • Adults: 65-90 mg per day
  • Upper limit: 2000 mg per day

During times of increased need, such as when fighting a cold, higher doses may be taken for short periods. However, it’s always best to consult with a healthcare provider before significantly increasing supplement intake.

Forms of Zinc and Vitamin C: Which to Choose?

When selecting zinc and vitamin C supplements, you’ll encounter various forms. For zinc, common options include zinc picolinate, zinc gluconate, and zinc orotate. Vitamin C is often found as ascorbic acid or in buffered forms like calcium ascorbate.

Is there a significant difference between these forms? In most cases, the benefits of different forms like zinc orotate vs. zinc picolinate are minimal. The key is to choose a reputable brand and a form that’s well-tolerated by your body.

For optimal absorption:

  • Take zinc supplements on an empty stomach or with a small amount of food
  • Spread vitamin C intake throughout the day (e.g., 250 mg at breakfast and 250 mg at lunch)
  • Consider taking vitamin C with meals to reduce potential gastrointestinal discomfort

Potential Side Effects and Interactions

While zinc and vitamin C are generally safe when taken as directed, it’s important to be aware of potential side effects and interactions. Can taking these supplements together cause any issues?

In most cases, combining zinc and vitamin C doesn’t pose significant risks. However, high doses of either nutrient can cause side effects:

  • Zinc: Nausea, vomiting, loss of appetite, abdominal cramps, diarrhea, headaches
  • Vitamin C: Diarrhea, nausea, abdominal cramps, headaches

To minimize digestive issues from high-dose vitamin C, consider taking it with magnesium. Be cautious when using zinc nasal sprays, as they’ve been linked to loss of smell in some cases.

It’s also important to note that zinc can interfere with the absorption of certain antibiotics and other medications. Always inform your healthcare provider about all supplements you’re taking.

Zinc and Vitamin C for Cold Prevention and Treatment

One of the most common reasons people turn to zinc and vitamin C supplements is to fight off colds. But how effective are these nutrients in preventing and treating the common cold?

Research on zinc for colds has shown mixed results, but some studies suggest that zinc lozenges or syrup taken within 24 hours of symptom onset may reduce the duration of colds by about a day. Vitamin C, while not proven to prevent colds in the general population, may slightly reduce the duration and severity of symptoms.

For best results:

  • Start taking zinc at the very first sign of cold symptoms
  • Use zinc lozenges or syrup for direct contact with the throat
  • Maintain consistent vitamin C intake before and during illness
  • Don’t expect miracles – these nutrients support your immune system but aren’t a cure

Remember, while supplements can be helpful, they shouldn’t replace a balanced diet rich in fruits, vegetables, and other nutrient-dense foods.

Dietary Sources of Zinc and Vitamin C

While supplements can be beneficial, obtaining nutrients from food sources is often ideal. What are some of the best dietary sources of zinc and vitamin C?

Zinc-rich foods include:

  • Oysters
  • Beef
  • Crab
  • Lobster
  • Pork chops
  • Baked beans
  • Pumpkin seeds

Vitamin C-rich foods include:

  • Citrus fruits (oranges, grapefruits, lemons)
  • Strawberries
  • Bell peppers
  • Broccoli
  • Brussels sprouts
  • Potatoes
  • Tomatoes

Incorporating these foods into your diet can help ensure you’re getting adequate amounts of both nutrients. However, during times of increased need or if dietary intake is insufficient, supplements can fill the gap.

Other Nutrients That Support Immune Function

While zinc and vitamin C are important for immune health, they’re not the only nutrients that play a role. What other vitamins and minerals should you consider for optimal immune support?

  • Vitamin D: Crucial for immune cell function and reducing inflammation
  • Vitamin E: An antioxidant that helps protect cells from damage
  • Selenium: Supports the production of immune cells
  • Iron: Necessary for the proliferation of immune cells
  • Probiotics: Beneficial bacteria that support gut health and immune function

A well-rounded approach to immune support includes a balanced diet, regular exercise, adequate sleep, and stress management. Supplements can complement these lifestyle factors but shouldn’t be relied upon as a sole means of immune protection.

Combining Multiple Immune-Supporting Supplements

When considering multiple supplements for immune support, it’s important to be mindful of potential interactions and proper dosing. Always consult with a healthcare provider before starting any new supplement regimen, especially if you have underlying health conditions or are taking medications.

Some effective combinations for immune support include:

  • Zinc + Vitamin C + Vitamin D
  • Vitamin C + Elderberry + Echinacea
  • Probiotics + Vitamin D + Zinc

Remember that more isn’t always better when it comes to supplements. Stick to recommended dosages and focus on consistency rather than megadosing.

The Role of Zinc and Vitamin C in Overall Health

Beyond immune support, zinc and vitamin C play vital roles in numerous bodily functions. Understanding these broader health benefits can help you appreciate the importance of maintaining adequate levels of these nutrients.

Zinc’s Multifaceted Health Benefits

Zinc is involved in numerous aspects of cellular metabolism and is required for the activity of over 300 enzymes in the body. Some key functions include:

  • DNA synthesis and cell division
  • Protein synthesis
  • Wound healing
  • Growth and development
  • Taste and smell perception

Zinc deficiency can lead to a range of health issues, including impaired immune function, delayed wound healing, hair loss, and decreased sense of taste and smell. Ensuring adequate zinc intake is crucial for overall health and well-being.

Vitamin C’s Wide-Ranging Impact

As a powerful antioxidant, vitamin C offers numerous health benefits beyond immune support:

  • Collagen production for skin health and wound healing
  • Cardiovascular health support
  • Enhanced iron absorption
  • Potential cognitive benefits
  • Skin protection against UV damage

Vitamin C’s ability to neutralize free radicals may help reduce the risk of certain chronic diseases and support overall health. While severe vitamin C deficiency (scurvy) is rare in developed countries, suboptimal levels can still impact health and well-being.

Special Considerations for Specific Populations

While zinc and vitamin C are generally beneficial, certain groups may have unique needs or considerations when it comes to supplementation. Who might need to pay special attention to their intake of these nutrients?

Pregnant and Breastfeeding Women

Pregnant women have increased needs for both zinc and vitamin C. Adequate zinc is crucial for fetal development, while vitamin C supports the immune system and helps with iron absorption. However, excessive supplementation should be avoided. Always consult with a healthcare provider for appropriate dosing during pregnancy and breastfeeding.

Older Adults

As we age, nutrient absorption can decrease, and the immune system may become less efficient. Older adults may benefit from ensuring adequate zinc and vitamin C intake through diet and supplements. However, they should be cautious with high doses, as the risk of interactions with medications may increase with age.

Vegetarians and Vegans

Plant-based diets can be low in zinc, as the best sources are often animal products. Vegetarians and vegans may need to pay extra attention to their zinc intake and consider supplementation. Vitamin C is generally abundant in plant-based diets but should still be monitored.

Individuals with Certain Health Conditions

People with conditions that affect nutrient absorption, such as inflammatory bowel disease or certain genetic disorders, may have increased needs for zinc and vitamin C. Additionally, those with a history of kidney stones should be cautious with high-dose vitamin C supplements.

In all cases, it’s essential to work with a healthcare provider to determine the appropriate intake of zinc and vitamin C based on individual needs and health status.

Debunking Myths About Zinc and Vitamin C

As with many popular supplements, there are several myths and misconceptions surrounding zinc and vitamin C. Let’s address some common misunderstandings to ensure you have accurate information.

Myth: Megadosing Vitamin C Prevents Colds

While vitamin C is important for immune function, taking extremely high doses (like 1000 mg or more) hasn’t been shown to prevent colds in the general population. Moderate, consistent intake is more beneficial than sporadic megadoses.

Myth: Zinc Can Replace Antibiotics

Zinc supports immune function but is not a substitute for antibiotics in treating bacterial infections. Antibiotics are specifically designed to target bacteria, while zinc plays a supportive role in overall immune health.

Myth: Natural Forms of Vitamins Are Always Better

While obtaining nutrients from whole foods is ideal, synthetic vitamins are not inherently inferior. The body often doesn’t distinguish between natural and synthetic forms of vitamins, and synthetic forms can be more cost-effective and easier to standardize in supplements.

Myth: You Can’t Overdose on Water-Soluble Vitamins

While it’s true that excess water-soluble vitamins like vitamin C are generally excreted in urine, very high doses can still cause side effects. It’s important to stick to recommended dosages even with water-soluble vitamins.

By understanding these myths and focusing on evidence-based information, you can make more informed decisions about using zinc and vitamin C supplements for your health.

Can I Take Zinc & Vitamin C at the Same Time?

Can I Take Zinc & Vitamin C at the Same Time?

Image Credit: HandmadePictures/iStock/GettyImages

Eating a varied diet of fresh fruits and vegetables, lean proteins, complex carbohydrates and healthy fats should provide you with all the recommended daily amounts of vitamins and minerals that you need. Sometimes, though, especially in the early stages of a cold or the flu, life gets in the way. Loss of appetite means loss of nutrition. Taking supplements may not stave off or shorten the duration of a cold or the flu, but taking in enough vitamin C, zinc and other nutrients can help support your body while it fights off the illness.

Tip

There is absolutely no reason you cannot take vitamin C and zinc together, because they do not work at cross purposes with each other.

What You Need to Know About Zinc

Zinc supports your immune system, helps wounds to heal and supports efficient functioning of your metabolism, according to the Mayo Clinic. Zinc deficiencies are rare in the United States, but symptoms include inability to taste foods, slower healing of wounds, frequent infections and hair loss.

Taking zinc for colds when the very first symptoms appear may help you get over the sniffles a little faster, though it’s best to take in lozenge form; zinc nasal sprays have been linked to loss of smell, which in some cases is permanent.

Read more: Side Effects of Not Enough or Too Much Zinc

Basic Facts About Vitamin C

Vitamin C helps support your immune system and promotes the formation of collagen, which makes up a large part of the connective tissue in your body. Collagen is also necessary for the production of the hemoglobin that carries oxygen throughout your body.

Vitamin C is also a powerful antioxidant that helps scrub free radicals from your cells, lowering your risk of heart attack, stroke and some cancers. In addition, according to the University of Rochester Medical Center, vitamin C might help ease the symptoms of a cold and shorten the time you need to get over it.

Vitamin C helps your body absorb iron and generally does not interfere or compete with other vitamins, so unlike taking calcium and magnesium — which compete with each other for absorption — you can safely combine vitamin C and zinc.

Read more: What Citrus Fruit Has the Most Vitamin C?

How to Take Vitamin C and Zinc Together

According to Randall Wexler, MD, at Ohio State University Wexner Medical Center, taking an over-the-counter cold remedy probably won’t have much actual effect on your cold, but if it makes you feel better, that’s reason enough to go ahead and take it. Read the label on any cold remedy to make sure nothing in it will affect the medications you take on a daily basis.

Taking magnesium and vitamin C together can help ease the digestive issues like upset stomach and diarrhea that high doses of vitamin C can cause, according to the supplement experts at ConsumerLab. You can also take each supplement — such as magnesium, vitamin C and zinc — in separate lozenges, tablets or gel tabs rather than relying on a premixed cold remedy.

When choosing zinc, the benefits of zinc orotate vs. zinc picolinate are minute enough to make no real difference. Both are formulated to be absorbed quickly. The recommended dose of zinc is 8 milligrams for women and 11 mg for men. If you wish to take more in order to stave off or shorten a cold, take no more than 40 mg per day. Take 250 mg of vitamin C at breakfast and another 250 mg at lunch to keep your levels up all day.

Read more: What Form of Zinc is Best?

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    Do vitamin C, zinc combat Covid-19? Here’s what new research reveals.

    Vitamin C and zinc are commonly used to stave off or reduce the severity of colds and flu—but what’s their effect on Covid-19? Findings from the first randomized clinical trial of the two supplements’ effects on Covid-19 suggest “unimpressive” results, Sandee LaMotte writes for CNN.

    The Covid-19 resources you need right now

    Background

    According to CNN, many people use vitamin C and zinc supplements in an effort to combat viral colds and the flu—and past research suggests these supplements can be modestly helpful in reducing the length of these common infections.

    For instance, supplements of vitamin C, an antioxidant that provides critical support to the immune system, have been shown to shorten the duration of colds by 8% among adults and by 14% among children—although taking the supplement doesn’t appear to prevent illness, nor does taking it after symptoms begin seem to help.

    Similarly, a literary review of zinc—which plays a key role in regulating metabolism and the immune system—found that if the supplement is taken within 24 hours of when cold symptoms first present, it may cut the length of a cold by a day.  

    More recently, researchers have started to explore whether the supplements can protect against Covid-19, or at least reduce the severity of infection.

    Early research conducted last year found that among hospitalized Covid-19 patients, each unit increase in zinc-blood level was associated with a 7% lower risk of in-hospital death—although the researchers looked only at levels of zinc in patients’ blood, not the effects of zinc supplementation.

    Separately, a retrospective observational study of hospitalized Covid-19 patients found that patients treated with zinc in combination with the antimalaria drug hydroxychloroquine and the antibiotic azithromycin were less likely to die or be transferred to hospice care when compared with patients who received the other drugs but not zinc. However, the study was not a randomized controlled trial, so it could not determine whether zinc actually caused the observed reduction in risk.

    New findings

    For the latest study, published in JAMA Network Open, researchers divided 214 study participants, all of whom were recovering from Covid-19 at home, into four groups. One group received gave high doses of zinc, the second group got high doses of vitamin C, and the third group received high doses of both drugs. The fourth group acted as a control, receiving only standard care such as rest and fever-reducing drugs.

    Ultimately, the researchers found the supplements provided no benefit to study participants. In fact, the results were so “unimpressive,” LaMotte reports, that the researchers ended the study early.

    “Unfortunately, these 2 supplements failed to live up to their hype,” Erin Michos, an associated professor of medicine at John Hopkins University School of Medicine, and Miguel Cainzos-Achirica, an assistant professor of preventive cardiology at Houston Methodist, wrote in an editorial accompanying the study. Further, they noted that the high doses of the supplements were linked to unpleasant side effects, including “nausea, diarrhea, and stomach cramps.”

    However, according to LaMotte, other researchers are still investigating potential effects of these and other supplements in preventing or treating Covid-19, with studies in progress on vitamin C, vitamin D, and zinc (LaMotte, CNN, 2/12).

    Zinc, vitamin C supplements does not decrease duration of COVID-19 symptoms: study

    The study showed no significant difference between the usual care, vitamin C, zinc gluconate or the group receiving both vitamin C and zinc gluconate.

    Taking zinc or vitamin C supplements does not significantly decrease the severity or duration of symptoms in COVID-19 patients, when compared to standard care, according to a study.

    Researchers at Cleveland Clinic in the U.S. noted that zinc is known to be important for immune function, with a role in antibody and white blood cell production and fighting infections. Vitamin C, an antioxidant, can help reduce damage to cells, and has shown to be immune-boosting, they said.

    The COVIDAtoZ clinical trial enrolled 214 adult patients with a confirmed COVID-19 infection. The participants either received 10 days of zinc gluconate (50 mg), vitamin C (8000 mg), both agents, or standard of care from April 2020 to October 2020.

    The study, published in the journal JAMA Open Network, found no significant difference among the four groups.

    At 50% reduction in symptoms, the study showed no significant difference between the usual care, vitamin C, zinc gluconate or the group receiving both vitamin C and zinc gluconate.

    “When we began this trial, there was no research to support supplemental therapy for the prevention or treatment of patients with COVID-19,” said Milind Desai, from Cleveland Clinic’s Heart Vascular & Thoracic Institute and co-principal investigator of the study. “As we watched the pandemic spread across the globe, infecting and killing millions, the medical community and consumers alike scrambled to try supplements that they believed could possibly prevent infection, or ease COVID-19 symptoms, but the research is just now catching up.”

    “While vitamin C and zinc proved ineffective as a treatment when clinically compared to standard care, the study of other therapeutics continues,” he said. The patients enrolled in this study were not hospitalised, but rather managed on an outpatient basis.

    “We know that not all patients with COVID-19 require hospital admission, and compared to those being treated in a hospital setting, they are more likely to be seeking out supplements that could help them, so it was an important population to study,” said Suma Thomas, from Cleveland Clinic’s Heart Vascular & Thoracic Institute and co-principal investigator of the study.

    The researchers said a total of four safety events were observed during the trial, including three deaths. However, the data safety monitoring board did not believe that any of the adverse events were caused by individual treatments that patients received as a part of the study.

    Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds

    No, not even at high doses, according to the first randomized clinical trial to test the two supplements under medical supervision.

    Despite the popular use of vitamin C and zinc to fight off or lessen the severity of viral colds and flu, the new study, published Friday in JAMA Network Open, found the two supplements were of no benefit to people isolating at home with Covid-19.

    In fact, the findings were so unimpressive that the study was stopped early.

    “Unfortunately, these 2 supplements failed to live up to their hype,” wrote Dr. Erin Michos of John Hopkins and Houston Methodist’s Dr. Miguel Cainzos-Achirica, in an accompanying editorial.

    The clinical trial gave high doses of each supplement alone and in combination to one of three groups of 214 adults who were recovering at home. A fourth group got standard care, such as rest, hydration and fever-reducing medications, but no supplements.

    “High-dose zinc gluconate (zinc), ascorbic acid (vitamin C), or both supplements did not reduce SARS-CoV-2 symptoms,” according to Cleveland Clinic cardiologist Dr. Milind Desai and a team from Cleveland Clinic.

    The high doses, however, did cause some unpleasant side effects for patients taking the supplements.

    “More adverse effects (nausea, diarrhea, and stomach cramps) were reported in the supplement groups than in the usual care group,” wrote Michos, an associate professor of medicine at Johns Hopkins University School of Medicine, and Cainzos-Achirica, an assistant professor of preventive cardiology at Houston Methodist.

    Popular supplements

    Many Americans turn to vitamin C and zinc supplements to fight off viral colds and flu.

    Vitamin C is a recognized antioxidant, and plays an essential role in supporting the immune system. Even though it has not been shown to prevent illness, other research has found vitamin C can shorten colds by 8% in adults and 14% in kids.

    Using vitamin C after cold symptoms start, however, doesn’t appear to be helpful, according to the National Institutes of Health.

    Zinc may help a cell’s ability to fight infection, the study said, “while there is evidence that zinc deficiency increases pro-inflammatory cytokines and decreases the production of antibodies.”

    But what does that mean in real life? If taken within 24 hours of the very first signs of a cold, zinc may reduce the length of a cold by only one day, a a review of 13 studies found.There is a down side, too. Taking over 2,000 milligrams of vitamin C a day can cause heartburn, stomach cramps, nausea, vomiting, diarrhea and headaches. The average daily recommended amount of vitamin C is 75 milligrams for adult women and 90 milligrams for men.

    Over 40 milligrams of zinc each day can cause dry mouth, nausea, loss of appetite and diarrhea, plus it can have a nasty metallic taste.

    Long-term users can have “low copper levels, lower immunity, and low levels of HDL cholesterol (the ‘good’ cholesterol),” according to the NIH. In 2009, the FDA warned the public against using zinc nasal sprays because they were linked to more than 100 cases of loss of smell.

    Research continues

    Scientists are continuing to explore the use of vitamins and supplements in the treatment of Covid-19.

    Randomized trials are currently underway to see if vitamin D supplements can help — in addition to supporting healthy bone growth, vitamin D has anti-inflammatory properties.

    Researchers in the US and China are using intravenous doses of vitamin C to determine if it might help people with respiratory failure severe enough to be put on a ventilator.

    And more studies are in progress to see if Covid-19 can be prevented by supplements such as vitamins C and D and zinc.

    Based on this study, however, the use of vitamin C and zinc to shorten the duration of Covid-19 appears to be useless.

    CNN’s Maggie Fox contributed to this story.

    Vitamin C (Ascorbic acid) Information | Mount Sinai

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    Cook NR, Albert CM, Gaziano JM, Zaharris E, MacFadyen J, Danielson E, Buring JE, Manson JE. A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of cardiovascular events in women: results from the Women’s Antioxidant Cardiovascular Study. Arch Intern Med. 2007;167(15):1610-8.

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    Gandini S, Merzenich H, Robertson C, Boyle P. Meta-analysis of studies on breast cancer risk and diet: the role of fruit and vegetable consumption and the intake of associated micronutrients. Eur J Cancer. 2000;36:636-646.

    Head KA. Natural therapies for ocular disorders, part two: cataracts and glaucoma. Altern Med Rev. 2001;6(2):141-66.

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    Juraschek SP, Guallar E, Appel LJ, Miller ER. Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2012;95(5):1079-88.

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    Khaw KT, Bingham S, Welch A, et al. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition. Lancet. 2001;357:657-63.

    Kompauer I, Heinrich J, Wolfram G, Linseisen J. Association of carotenoids, tocopherols, and vitamin C in plasma with allergic rhinitis and allergic sensitization in adults. Public Health Nutr. 2006;9:472-9.

    Kurowska EM, Spence JD, Jordan J, Wetmore S, Freeman DJ, Piche LA, Serratore P. HDL-cholesterol-raising effect of orange juice in subjects with hypercholesterolemia. Am J Clin Nutr. 2000;72(5):1095-1100.

    Laight DW, Carrier MJ, Anggard EE. Antioxidants, diabetes and endothelial dysfunction. Cardiovasc Res. 2000;47:457-464.

    Langlois M, Duprez D, Delanghe J, De Buyzere M, Clement DL. Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis. Circulation. 2001;103(14):1863-1868.

    Lonn E. Do antioxidant vitamins protect against atherosclerosis? The proof is still lacking. J Am Coll Cardiol. 2001;38:1795-8.

    Lykkesfeldt J, Christen S, Wallock LM, Chang HH, Jacob RA, Ames BN. Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Am J Clin Nutr. 2000;71(2):530-536.

    Mares-Perlman JA, Lyle BJ, Klein R, et al. Vitamin supplement use and incident cataracts in a population-based study. Arch Ophthalmol. 2000;118:1556-63.

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    How To Take Vitamins Properly

    Answer:

    The question of when to take vitamins together or separately is an excellent one and which we address in the “What to Consider When Using” and “Concerns and Cautions” sections of our Reviews of vitamin or mineral supplements. How you take a supplement can be just as important as which product you take — both may impact how much of a nutrient your body actually gets.

    A few rules of thumb:

    • If you take a large dose of a mineral, it will compete with other minerals to reduce their absorption. The mineral most often taken in large amounts is calcium: The dose is usually several hundred milligrams, compared to doses of just a few milligrams or even microgram amounts (1,000 micrograms = 1 milligram) of most other minerals. So if you take several hundred milligrams of calcium from a supplement, take it at a different time of day than other mineral supplements or a multivitamin/multimineral supplement. Doses of magnesium can also be relatively large and should, ideally, be taken apart from other minerals. If you take high doses of zinc long-term (50 mg or more per day for 10 weeks or longer ), be aware that it can cause copper deficiency, so you may need to supplement with copper as well.


    • High doses of calcium or other minerals (including magnesium, certain forms of iron, and zinc) from supplements may decrease the absorption of carotenoids, such as beta-carotene, lycopene and astaxanthin, from foods and/or supplements. It is best to take carotenoid supplements at a different time of day than a supplement or meal containing large amounts of a mineral (e.g., hundreds of milligrams of calcium or magnesium).

    • Some vitamins can actually enhance the absorption of other nutrients. Vitamin C, for example, can enhance iron absorption from supplements and plant foods.

    • The fat-soluble vitamins (A, D, E, and K) are likely to be better-absorbed if taken with a meal that contains fats. In fact, one study found that taking vitamin D with dinner rather than breakfast increased blood levels of vitamin D by about 50%. However, evidence (mainly from animal and cell studies) suggests that moderate to large doses of fat-soluble vitamins reduce absorption of other fat-soluble vitamins – by about 10 to 50% – due to competition. Absorption of vitamin K appears to be particularly reduced by other fat-soluble vitamins, while vitamin A absorption is least affected and may actually be better absorbed when taken with vitamin E (Goncalves, Food Chem 2015). Taking vitamins D, E, or K several hours before or after other fat-soluble vitamins would seem to maximize their absorption.

    • Taking certain supplements with food can reduce gastrointestinal side-effects. For example, taking magnesium with food can reduce the occurrence of diarrhea, and taking iron with food can reduce the chance of stomach upset.

    • Be aware that vitamins and minerals can also affect the absorption and effectiveness of medications. You’ll find more specific information about this in the “Concerns and Cautions” section of each of our Reviews.

    Keep in mind that these issues are not of significant concern when consuming a multivitamin providing up to the recommended daily intakes (RDAs) of vitamins and minerals — as long as it does not contain more than 250 mg of either calcium or magnesium.

    90,000 Zinc, Selenium and Vitamin D. How to Protect Against COVID-19?

    The curve of cases of coronavirus infection has crept up. But science does not stand still. The piggy bank of knowledge about the disease is replenished, and more and more new methods of treatment and prevention appear.

    Antiviral cocktail

    How to protect yourself from COVID-19 before the vaccine is available to everyone? And what about those to whom this vaccine is contraindicated for one reason or another?

    Many doctors believe that a cocktail of three components – zinc, selenium and vitamin D provides good antiviral protection.

    “The role of trace elements in the functioning of the immune system and protection against viruses is great, and we decided to see what their significance is in the severity of the course of COVID-19,” says Andrey Svistunov, Doctor of Medical Sciences, Professor, First Vice-Rector of Sechenov University. – Since we have a database of several hundred patients with this infection who were treated in our clinic, we checked the concentration of many trace elements in their blood serum. A clear relationship was found – the lower the level of zinc and selenium, the more severe the course of the disease.And vice versa – with a normal content of these trace elements, there was more often a mild course of COVID-19. ”

    “The role of zinc in this study was expected, but this is the first time such large-scale data on the important role of selenium in protection against COVID-19 have been obtained,” says Anatoly Skalny, MD, professor, head of the molecular nutrition laboratory at Sechenov University and ideologist of this study. – The direct antiviral effect of zinc, including against the coronavirus, is well studied.It inhibits its reproduction (replication) in the cell. Plus zinc strengthens the immune system, affecting many parts of the immune system. Vitamin D has the same effect.Additional intake of this vitamin for the prevention of coronavirus infection is prescribed in many official recommendations. Selenium can also affect immunity, including congenital, which plays a large role in COVID-19. In addition, it protects the lungs and, together with zinc, is important in reducing the inflammatory response. We know well what a negative role excessive inflammation plays in coronavirus infection: a cytokine storm is the most important factor in its severe course.And, possibly, selenium plays a significant role in its weakening.

    After reviewing these facts with a large international group of scientists, we came to the conclusion that zinc, selenium and vitamin D are optimal for the prevention of COVID-19 and for its treatment from the very beginning of the disease. After all, all these components are important for the production of antibodies and the good functioning of the immune system. We wrote an article about this, published in the influential scientific journal Nutrients, and now, with leading scientists, including the Nobel laureate Konstantin Novoselov, we are preparing a book on the role of micronutrients in COVID-19.It will be released in the US and will be available to all doctors. ”

    How do I enable triple protection?

    “Unfortunately, the inhabitants of most of the territory of Russia lack each of these three substances,” says Anatoly Skalny. – For example, 30–40% of Russians have a zinc deficiency. Among elderly people with diabetes mellitus, obesity, frequent colds and chronic diseases of the lungs, liver or alcohol abusers, zinc and selenium deficiency is observed in 60–80%.Given this situation, drugs can be taken without examining their content in the body. But this can be done no longer than 3 months and in moderate doses. For zinc it is 5-10 mg per day, for selenium – 50 mcg, for vitamin D – the daily intake of 600-800 IU (15-20 mcg). In any case, this will strengthen the immune system.

    But it is better, of course, to do an analysis and check the content of the components of the “triple cocktail” in the body. All of them can be determined in the blood, and zinc and selenium can also be found in the hair.In case of a serious deficiency, the reception is needed longer, and the doses – more. For zinc it is 80 mg per day, for selenium – 100-200 mcg. If a person is infected with coronavirus, then such doses can be taken within 3 weeks – this will help in treatment. Remember to eat well with adequate amounts of food rich in these nutrients. Note that many foods are high in zinc and selenium at the same time, and eggs are rich in all three.


    Publication link:
    Arguments and Facts

    90,000 When to take vitamins so that they are better absorbed by the body?

    To get the most out of vitamins and nutritional supplements (vitamin D, magnesium, iron, B vitamins, etc.)take them at the right time of day as this can make a big difference, and do not exceed the recommended dose indicated on the package unless advised by a nutritionist or doctor.

    This guide summarizes the results of many studies showing which combinations to avoid, which to take with meals, which in the morning on an empty stomach, and which in the evening before bed.

    Morning

    Iron
    Iron is the main component of hemoglobin.Low iron levels can lead to fatigue and weaken the immune system. It is best to take iron on an empty stomach. Do not take it with tea or coffee, as tannins and caffeine can interfere with iron absorption. Calcium also interferes with iron absorption, so don’t take them at the same time.

    Vitamin C
    Supports normal functioning of the immune system, increases energy, strong antioxidant. Vitamin C is retained in the body for only a few hours, so it is best to divide the dose over the whole day.Start taking it in the morning and set reminders to remember to take it throughout the day. Nutritional supplement and medication reminders can be easily added to the myEmerg – Appstore health app.

    Vitamins of group B
    Help to ensure normal metabolism of energy production, contribute to the normal functioning of the nervous system, help reduce fatigue, and contribute to normal psychological functions. Take B vitamins with breakfast to increase and maintain energy throughout the day.

    Vitamin E
    Protects body cells from damage caused by free radicals. Essential for maintaining cardiovascular health. Better absorbed when taken with fats such as yogurt, milk, nuts, or avocados.

    MORNING / DAY

    Coenzyme Q10
    Promotes energy processes in cells, delays aging of the body, improves the body’s defenses, i.e. immunity, increases physical endurance.It is found in almost all cells, most of all in organs that require a lot of energy for their work – in the heart, brain, liver, kidneys. Coenzyme Q10 is better absorbed when taken with dietary fats – ideally at breakfast or lunch to avoid negative effects on sleep.

    Zinc
    Zinc contributes to the normal functioning of the immune system, fertility and the reproductive system. Zinc is an essential mineral. It is found in large quantities in foods rich in protein – fish, seafood, nuts, seeds.Take zinc during the day with meals as it can cause nausea when taken on an empty stomach. Do not take it at the same time as calcium or iron.

    Iodine
    Iodine takes care of the synthesis of thyroid hormones and the health of the skin. Iodine does not accumulate in the body, so it must be taken regularly. Iodine is a trace mineral found naturally in or added to food. The richest sources of iodine are seaweed, shrimp, cod liver and milk. Studies have found iodine boosts energy, so take it in the afternoon to boost your energy levels.

    DAY / EVENING

    Vitamin D
    Vitamin D is important for bone health, immunity, and lowers the risk of heart disease, diabetes and certain cancers. It is very important for the absorption of calcium and phosphorus. It forms naturally in the skin when exposed to sunlight, but only if the UV index is higher than UV3. This means that during the period from October to April, the sunlight is not intense enough to synthesize vitamin D in the body. Vitamin D is best absorbed from food in the presence of dietary fats.Some studies have found that it can leave a negative effect on sleep, so take vitamin D immediately after lunch.

    Vitamin K
    Helps in the process of blood clotting, aids in wound healing, contributes to the maintenance of healthy bones. Vitamin K is a fat-soluble vitamin. Most of all are found in broccoli, cabbage, spinach, beets, parsley and vegetable oils (soybean, rapeseed). Vitamin K can be taken at any time, but is best taken with vitamin D, calcium, and vitamin C.It is better absorbed when taken with food, along with dietary fats.

    Fish Oil
    Contains essential omega-3 fatty acids for the body, which are essential for normal brain function, heart and eye health, growth and development of the body. The body itself does not produce omega-3 fatty acids; they can only be obtained from food or nutritional supplements. It is best to take fish oil with meals for better absorption.

    EVENING / NIGHT

    Calcium
    Calcium is an essential mineral for the body.A large amount of calcium is found in bones and teeth. It is used in the conduction of nerve impulses and for the function of muscles. Many people advise taking calcium in the evening because it is then absorbed best.

    Magnesium
    The fourth most important mineral in the body, 50% of magnesium is found in the bones. Promotes healthy bones and teeth. It also has a calming effect on the muscles and the nervous system. Studies show that magnesium improves sleep, so it should be taken in the evening before bed.

    Triple power of vitamins

    We have prepared for you an article on the benefits of vitamins D, zinc and selenium , their properties in the prevention of coronavirus infection.

    A number of studies have revealed the dependence of the concentration of vitamin D, zinc, and selenium on the severity of the course of the disease COVID-19 : the lower the level of these substances, the more severe the course of the disease. And vice versa – with a normal content of these trace elements, a mild course of COVID-19 was more often observed and the likelihood of infection was lower.

    Vitamin D

    Researchers at the University of Chicago Medical University found that those people who were deficient in vitamin D (<20 ng / ml) and were not treated were almost twice as likely to test positive for COVID-19 as those who had a sufficient level of vitamin.

    The relative risk of testing positive for COVID-19 was 1.77 times higher for patients with probable vitamin D deficiency compared with patients with probable sufficient vitamin D status, a difference that was statistically significant, “the authors stated in a recent publication in JAMA Network Open Study Materials.

    Vitamin D affects zinc metabolism, which reduces the ability of coronaviruses to replicate. The research team also stated that “higher levels of vitamin D correlate with lower levels of interleukin 6, which is a primary target for controlling the cytokine storm in COVID-19.”

    Despite its name, vitamin D is actually a hormone that is responsible for the absorption of calcium by the body.

    It is almost nowhere else, except in fatty fish and eggs, but under the influence of ultraviolet rays, our skin produces its own hormone from ordinary cholesterol.

    Zinc

    “The required level of zinc in the body can reduce the likelihood of respiratory infections, pneumonia and its complications,” said the scientists. Zinc plays an important role in the regulation of immunity and maintains resistance to inflammation, therefore its effect on the body is considered in many studies in terms of preventing COVID-19.

    Elevated zinc levels in rhinoviruses indicate a slowdown in viral reproduction (replication) and stimulation of the production of interferon alpha, which has antiviral activity.

    Zinc also enhances immunity by affecting many parts of the immune system. Vitamin D has the same effect.Additional intake of this vitamin for the prevention of coronavirus infection is prescribed in many official recommendations.

    Good sources of zinc are lamb, beef, chicken, oysters and lobsters. For better assimilation of zinc, they should be consumed with vegetables. In addition, black rice, black sesame seeds, soy foods, mushrooms, celery, legumes, lentils, nuts, sunflower seeds, and almonds are also good sources of zinc.

    Selenium

    Selenium (Se), a naturally occurring trace mineral, plays a key and complex role in the immune system. Selenium deficiency has been documented to be associated with a higher susceptibility to viral RNA infections and a more severe disease outcome.

    Infections such as COVID-19, colds, flu and herpes are caused by different types of RNA viruses that can easily mutate (change their antigens). This means that the immune defense must start over from the recognition process.This is especially problematic in immunocompromised situations. Selenium plays a vital role here.

    Selenium is found in large quantities in nuts (pistachios and walnuts), beans, corn, peas, lard, garlic, sea fish, buckwheat, oatmeal, rice, sunflower seeds.

    Unfortunately, the inhabitants of most of the territory of Russia lack each of these three substances.

    For example, 30–40% of Russians have a zinc deficiency. Among elderly people with diabetes mellitus, obesity, frequent colds and chronic diseases of the lungs, liver or alcohol abusers, zinc and selenium deficiency is observed in 60–80%.Given this situation, drugs can be taken without examining their content in the body. But this can be done no longer than 3 months and in moderate doses.

    For zinc it is 5-10 mg per day, for selenium – 50 mcg, for vitamin D – the daily intake of 600-800 IU (15-20 mcg). This will strengthen the immune system in any case.

    But it is better, of course, to make an analysis and check the content of the components of the “triple cocktail” in the body.

    In case of a serious deficiency, the admission is needed longer, and the doses – more, which are determined by the attending physician.

    Do not forget about proper nutrition with a sufficient amount of food rich in these substances.

    Be healthy. Take care of yourself and your loved ones!

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    90,000 WHO answered whether to take vitamins for the prevention or treatment of COVID-19 | Hromadske television

    This was announced by the head of the WHO office in Ukraine, Dr. Jarno Habicht, in response to an inquiry from Radio Liberty.

    Habicht noted that vitamins D and C and zinc are critical for the well functioning of the immune system and play a vital role in promoting health and healthy eating. In particular, sources of vitamin D are oily fish: for example, salmon, tuna and mackerel, fish oil, beef liver, cheese and yolks, as well as foods or supplements containing vitamin D.

    According to the head of the WHO office in Ukraine, vitamin D It is recommended to use it if a person has a maximum indicator or when he does not consume foods containing vitamin D, and the effect of sunlight is limited.Doses – 200-600 IU (international units), depending on age, or in accordance with national recommendations.

    At the same time, one should be aware of the harmful effects of excessive vitamin D intake – these are hypercalciuria and hypercalcemia. They do not occur within the recommended consumption levels, the head of the WHO added.

    To stay healthy, says the head of the WHO in Ukraine, you should eat healthy food, maintain physical activity and follow general recommendations on physical distance, wear a mask, use a disinfectant and be at home if you feel unwell.

    Why is it worth knowing about it?

    Recently, there have been reports in the media that some studies show that people with vitamin D deficiency are likely to have a higher risk of contracting COVID-19 with a severe course of the disease. There have been reports of zinc as a “shield” against the coronavirus.

    According to the Liki24.com service to Radio Liberty, the demand for vitamins in Ukraine has grown significantly since the beginning of the pandemic and “remains stably high” .

    According to these data, most often users of the service are looking for vitamin D for both adults and children – in the last two weeks of October, the number of such requests has doubled.The demand for zinc, they add, has increased sevenfold, while the prices for vitamins in pharmacies remain stable.

    The doctor told whether the combination of vitamins will help to avoid severe forms of COVID-19

    Photo: depositphotos / avemario

    Allergologist-immunologist Vladimir Bolibok, in an interview with Moscow 24, commented on the recommendation of foreign scientists to take a combination of vitamins to reduce the risk of severe COVID-19 disease.

    Earlier, a member of the scientific and technical committee on coronavirus infection under the regional government of Sicily, professor of medicine Salvatore Corrao told RIA Novosti that the use of vitamins C and D, melatonin and zinc helps to avoid severe forms of COVID-19.

    He says that 1-2 grams of ascorbic acid (vitamin C) should be taken daily to reduce risks. Vitamin D can be consumed both daily and once a month. The optimal solution, according to the expert, would be a one-time use of 50 thousand international units per month. And preferably on a full stomach, the Italian expert added.

    He also advised taking 6 to 10 milligrams of melatonin every night. It will help the immune system fight viruses and consume about 50 milligrams of pure zinc per day.However, after three months of use, the daily dose should be reduced to 25 milligrams, the expert said.

    Vladimir Bolibok noted that the proposed elements really have useful properties.

    “As for the preventive effect of zinc in COVID-19, the statement was made back in March 2020, when the pandemic was just beginning, and before that, in 2011, WHO issued recommendations for the prevention of pneumonia with zinc preparations. French doctors used dietary supplements with zinc and noticed that those who take them very rarely required hospitalization.They did not do clinical trials, but based on their experience they made such a statement, “said the expert.

    Melatonin is a well-known means of supporting the immune system, the doctor says. And vitamins C and D in this combination work in the body as antioxidants and have anti-inflammatory effects.

    The scheme may be working. But the key in it are melatonin and zinc. This is what directly supports the immune system

    Vladimir Bolibok

    doctor – allergist-immunologist

    However, the doses offered by foreign scientists, the interlocutor Moscow 24 called dangerous for the body.

    Photo: depositphotos / nikolasvn

    “The Italian doctor’s recommendation for vitamin D is an absolutely deadly megadose. It can even have toxic effects. When you consume an ultra-high dose of vitamin D, thrombosis can occur in the body. In fact, this is vitamin D poisoning. “- said the doctor.

    The expert has a similar opinion on the dosages of the remaining elements of the mix. This is due to the fact that the doses in the proposed scheme exceed international and Russian recommendations several times, the specialist explains.For example, with the recommended intake of vitamin C up to 100 milligrams per day in the proposed scheme, the dose is 2,000 milligrams.

    Let me emphasize right away that the proposed treatment regimen contains ultra-high doses of vitamins, zinc and the hormone melatonin. They are used as drugs, this regimen needs clinical trials.

    Vladimir Bolibok

    doctor – allergist-immunologist

    “The results of taking megadoses are negative. People drink, then they get complications.For example, megadoses of vitamin C lead to the development of urolithiasis. Moreover, in a complex form, “the expert warns.

    In Russia, the recommended daily intake of melatonin is 3 milligrams, noted the interlocutor of Moscow 24. Zinc is within 10 milligrams per day. Foreign scientists, according to the expert, prescribe therapeutic doses. do not fit in any way, he emphasized.

    “For example, the therapeutic doses of vitamin C are used in our country for acute respiratory diseases.But this is for a short period of time, for 5-6 days, but not for months, “the allergist-immunologist points out. The substances in such complexes are balanced and do not harm the body, the doctor says.

    Earlier, Rospotrebnadzor said that the severity of COVID-19 depends on the genetic characteristics of each person. Also, the department stressed that at the moment there is no data on the effect of BCG vaccination on the likelihood of infection.

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    90,000 Vitamins identified as reducing the risk of severe COVID-19

    This was stated by a member of the scientific and technical committee on coronavirus infection under the regional government of Sicily, professor of medicine Salvatore Corrao.

    Within six months, a group of scientists from Italy and San Marino analyzed and systematized almost all available medical publications on the effects on the human body of well-known nutraceuticals – vitamins C and D, melatonin and zinc.

    Researchers have been able to determine the dosage that can provide the desired beneficial effect.

    – For example, one to two grams of ascorbic acid (vitamin C), which is a good antioxidant, should be taken daily.As for vitamin D, it can be taken both daily and once a month. In our opinion, the optimal solution seems to be a one-time use of 50,000 IU (international units) of this substance per month, and preferably on a full stomach, – said Salvatore Corrao in an interview with RIA Novosti.

    The professor also advised taking 6 to 10 mg of melatonin every night. Corrao added that it should be borne in mind that it can cause drowsiness and is therefore contraindicated in some people.Taking about 50 mg of pure zinc per day, he noted, will help the immune system fight viruses. However, Corrao warned that this trace mineral gradually accumulates in the body, so after three months it is recommended to reduce the daily dose to 25 mg.

    The scientist added that we are talking about the therapeutic use of these substances, which have a variety of effects on the body.

    Corrao also said that eating fruits and vegetables containing the same minerals and vitamins is not a substitute for taking these nutraceuticals.The professor advised using a combination of at least two of these active substances, but since we are talking about therapy, it is better to take them under the supervision of a doctor.

    As Kubanskie Novosti reported, earlier scientists named the vitamin, the deficiency of which is associated with severe COVID-19.

    Specialists from the Turkish Medical University in Ankara studied blood samples from a group of healthy people and patients with COVID-19 who are in the intensive care unit in critical condition.It turned out that those infected with the coronavirus had a low concentration of retinol (a bioavailable form of vitamin A), even in the case of taking medications that prevent the body from excreting it.

    Scientists have previously reported that increased exposure to sunlight reduces the death rate from coronavirus infection.

    Scientists from the University of Edinburgh conducted a study in which they tracked the percentage of deaths from COVID-19 among the population in the regions, depending on different levels of ultraviolet radiation.

    So, they analyzed mortality rates from coronavirus in the continental United States and the northern territories of the country from January to April 2020. It turned out that in the sunnier areas of the United States, people from COVID-19 died less often. Similar results were demonstrated by similar studies in England and Italy.

    According to scientists, this is due to the ability of sunlight to not only replenish the level of vitamin D in the blood, but also stimulate the production of nitric oxide in the skin.This substance blocks the ability of the coronavirus to reproduce.

    90,000 What time of day is it better to take vitamins?

    The time when we drink this or that vitamin is very important in order to get the maximum benefit. Some vitamins need to be taken with food to improve absorption, while others need to be drunk on an empty stomach.

    Vitamins A, E, D, K

    Fat-soluble vitamins A, E, D and K are best absorbed by the body when taken with fat-containing foods.

    Calcium

    Calcium, important for the health of bones and teeth, in general, does not require any special dosage regimens. But if you are taking multiple supplements, keep in mind that it should not be combined with iron and zinc, which can displace calcium in the struggle for the body’s resources.

    B vitamins

    In addition to participating in the basic life processes of the body, including cellular metabolism, B vitamins can boast that they provide us with an additional boost of energy.So the best time for B vitamins is breakfast.

    Zinc

    Take during the day with food, as it may cause nausea if taken on an empty stomach. Do not combine with calcium and iron.

    Magnesium, Iron and Fiber

    All these supplements are more correct to take in the evening or even before bedtime. Why? Let’s go in order. Magnesium (although of course it all depends on the amount here) can have a laxative effect – and it is definitely not what you would like in the middle of the day.At the same time, caffeine can block the action of iron, so if you drink a lot of coffee, you should postpone the supplement until later. Finally, high amounts of fiber can interfere with the absorption of nutrients from breakfast, lunch, and dinner.

    Vitamin C

    Water-soluble vitamin C can be taken at any time of the day, but be sure to drink it with a glass of water to get all the bonuses.

    Omega-3

    The time of admission does not matter – you can take capsules both in the morning and in the evening.Traditionally, fish oil is taken with food, so as not to greatly distinguish between their taste, and this also contributes to better absorption.