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Cefdinir with food: Cefdinir: MedlinePlus Drug Information

Cefdinir – Uses, Side Effects, Substitutes, Composition And More

Prescription vs OTC: Prescription by Doctor required

Cefdinir is primarily used for treating community-acquired pneumonia, acute exacerbations of chronic bronchitis, acute bacterial otitis media, acute maxillary sinusitis, pharyngitis/tonsillitis, and uncomplicated skin and skin structure infections.

A few bacterial infections can be effectively treated with the help of Cefdinir. The drug is as cephalosporin antibiotic and kills bacteria that causes infection in the body. Before you start using Cefdinir ask your doctor more information about how it works and how the drug should be taken.

For instance, if you are pregnant or are trying to have a child or even breast feeding, check if it is still safe for you to take the drug. Patients with stomach problems, a disorder related to blood clotting, kidney issues and diabetes should also ensure safety of Cefdinir before taking it.

The drug can be consumed either with a meal or even without. For patients who have stomach problems it is recommended that they take the dose with food. When using Cefdinir, avoid taking any antacid which contains magnesium or aluminum. Ensure that you take the medicine regularly, preferable at the same time.

Cefdinir can lead to dizzy spells and make you feel extremely sleepy. It is thus best that you avoid driving or handling heavy machinery to prevent any accidents. It is important to know that the drug only treats infections that are caused by some bacteria. It has no effect on viral infections.

After acute overdose, most agents cause only nausea, vomiting, and diarrhea, although neuromuscular hypersensitivity and seizures are possible, especially in patients with renal insufficiency.

Hemodialysis may be helpful to aid in the removal of the drug from the blood but not usually indicated, otherwise most treatment is supportive or symptom directed following GI decontamination.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    The medicine is useful against the following conditions:

    Health issues vary person to person

    Take help from the best doctors
    • Hypersensitivity

    Below are some of the common side effects of this medicine:

    • Diarrhoea

    • Seizures

    • Headache

    • Nervousness

    • Rash

    • Urticaria

    • Pruritus

    • Is It safe with alcohol?

      This medicine may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).

    • Are there any pregnancy warnings?

      This medicine is probably safe to use during pregnancy.
      Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Does this affect kidney function?

      Caution to be advised in patients with impaired renal function. Dosing adjustment in renal impairment: Clcr
      Hemodialysis removes cefdinir; recommended initial dose: 300 mg (or 7 mg/kg/dose) every other day. At the conclusion of each hemodialysis session, 300 mg (or 7 mg/kg/dose) should be given. Subsequent doses (300 mg or 7 mg/kg/dose) should be administered every other day.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    • Is it safe to drive while on this medicine?

      This medicine affect the consciousness of the patient, thus driving must be avoided while taking it.

    This medication belongs to the class of an oral cephalosporin antibiotic. It works by preventing the synthesis of peptidoglycan in the bacterial cell walls, which in turn helps control and cure infections in the body.

      What are the interactions of Cefdinir ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you”re at risk of a drug interaction.

      • Interaction with Lab Test

        Patient taking this medicine might result with positive Coombs’ test. Kindly inform your doctor before any blood test is asked to be performed.

      • Interaction with Medicine

        • Decreased effect: Coadministration with iron or antacids reduces the rate and extent of cefdinir absorption.

        • Increased effect:
          Probenecid increases the effects of cephalosporins by decreasing the renal elimination in those which are secreted by tubular secretion.

        • Increased toxicity:
          Anticoagulant effects may be increased when administered with cephalosporins
      • Interaction with Disease

        Administer cautiously to penicillin-sensitive patients. There is evidence of partial cross-allergenicity and cephalosporins cannot be assumed to be an absolutely safe alternative to penicillin in the penicillin-allergic patient. Serum sickness-like reactions have been reported. Signs and symptoms occur after a few days of therapy and resolve a few days after drug discontinuation with no serious sequelae. Pseudomembranous colitis occurs; consider its diagnosis in patients who develop diarrhea with antibiotic use.

      FAQs about Cefdinir

      Ques: Is Cefdinir effective?

      Ans:

      Yes , Cefdinir is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Cefdinir too early, the symptoms may return or worsen.

      Ques: Can the use of Cefdinir cause diarrhea?

      Ans:

      Yes, the use of Cefdinir can cause diarrhea. Cefdinir is an antibiotic which kills the harmful bacteria but can also affect the helpful bacteria in your stomach or intestine and cause diarrhea. If diarrhea persists, consult your doctor immediately.

      Ques: What should you avoid while taking Cefdinir?

      Ans:

      While taking Cefdinir, you must avoid antacids containing aluminum or magnesium, or multivitamins. It is advised to take these medications at least 2 hours before or after taking the Cefdinir.

      Ques: What if I forget to take a dose of Cefdinir?

      Ans:

      If you forget a dose of Cefdinir, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

      Ques: How long does Cefdinir take to work?

      Ans:

      Usually, Cefdinir starts working soon after you take it. However, it may take some days to kill all the harmful bacteria and relieve your symptoms completely.

      Ques: Can I drink milk while taking Cefdinir?

      Ans:

      Yes, you may drink milk while taking Cefdinir. In fact, you must not take Cefdinir on an empty stomach and take it with food or milk to avoid stomach upset. If stomach upset occurs, please consult your doctor.

      Ques: What if I do not get better after using Cefdinir?

      Ans:

      Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.

      Ques: Can I stop taking Cefdinir when my symptoms are relieved or when I feel better?

      Ans:

      No, do not stop taking Cefdinir before completing the full course of treatment. You may start feeling better before the infection is completely cured. Still, you need to take this medicine for the prescribed duration to gain maximum benefit from the medicine.

      References

      • Cefdinir-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 18 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/cefdinir

      • Cefdinir-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 18 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00535

      • CEFDINIR suspension,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 18 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CEFDINIR

      Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

      Cefdinir Oral Capsule 300 mg – Health Information Library

      For treating bacterial infection.

      Generic Name: Cefdinir

      Instructions

      This medicine may be taken with or without food.

      Keep the medicine at room temperature. Avoid heat and direct light.

      Do not take this medicine with antacids.

      Do not take any antacid or vitamins with magnesium, calcium, aluminum, or iron for 2 hours before and 2 hours after taking this medicine.

      If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

      Tell your doctor and pharmacist about all your medicines. Include prescription and over-the-counter medicines, vitamins, and herbal medicines.

      Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

      If you have diabetes and use urine glucose tests, this medicine may cause incorrect results. Please check with your doctor before making any changes to your diabetes treatment plan.

      Keep all appointments for medical exams and tests while on this medicine.

      Cautions

      Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

      Do not use the medication any more than instructed.

      Contact your doctor if you notice a change in the amount or darkening of your urine.

      Speak with your health care provider before receiving any vaccinations.

      Please tell your doctor if you have moderate to severe diarrhea while on this medicine. Do not treat the diarrhea with over-the-counter diarrhea medicine.

      Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

      Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

      Do not share this medicine with anyone who has not been prescribed this medicine.

      Side Effects

      The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

      • diarrhea
      • changes in the color of the urine or stool
      • headaches
      • nausea and vomiting
      • stomach upset or abdominal pain
      • yeast infection of mouth
      • vaginal itching or yeast infection

      Call your doctor or get medical help right away if you notice any of these more serious side effects:

      • confusion
      • severe, watery or bloody diarrhea
      • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
      • red, burning, or itchy skin
      • increased urinary frequency
      • urinating less often

      A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

      Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

      IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.

      There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.

      The display and use of this drug information is subject to Terms of Use.

      https://api.meducation.com/V2.0/fdbpem/4269

      Copyright(c) 2023 First Databank, Inc.

      Selected from data included with permission and copyright by First DataBank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

      Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.

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      Health Information Library

      Maalox tab.

      zhev.b/sugar No. 10 with free home delivery from VkusVill

      VkusVill

      Interaction with other drugs With quinidine With simultaneous use with quinidine, an increase in serum concentrations of quinidine and the development of an overdose of quinidine are possible. With H2-histamine receptor blockers, propranolol, atenolol, cefdinir, cefpodoxime, metoprolol, chloroquine, prostacyclins, diflunisal, digoxin, bisphosphonates, ethambutol, isoniazid, fluoroquinolones, sodium fluoride, glucocorticosteroids (described for prednisolone and dex amethasone), indomethacin, ketoconazole, lincosamides, phenothiazine antipsychotics, penicillamine, rosuvastatin, iron salts, levothyroxine. When taken simultaneously with Maalox®, the absorption of the above drugs in the gastrointestinal tract is reduced. In the case of a 2-hour interval between taking these drugs and Maalox® and a 4-hour interval between taking fluoroquinolones and Maalox®, in most cases this undesirable interaction can be avoided. With polystyrene sulfonate (kyexalate) When Maalox® is used together with polystyrene sulfonate (kyexalate) caution should be exercised because of the possible risk of reducing the efficiency of potassium binding by the resin and the development of metabolic alkalosis in patients with renal insufficiency (for aluminum hydroxide and magnesium hydroxide) and bowel obstruction (for aluminum hydroxide). With citrates When aluminum hydroxide is combined with citrates, an increase in plasma concentrations of aluminum is possible, especially in patients with renal insufficiency.

      Maalox tab. zhev.b / sugar №10 / Pharmacy

      Waiting for evaluation

      Vkusvill

      284 rub/piece 284.00 284.00

      from the partner “Pharmacy DIALOG Stolitsa”

      Features of the category “Pharmacy” Online payment only

      We deliver medical products of partners. Can be ordered separately, can be together with the products. Delivery times are the same.

      Partner licenses for pharmaceutical activity

      Description

      Interaction with other medicinal products
      With quinidine
      Concomitant use with quinidine may increase the serum concentrations of quinidine and develop an overdose of quinidine.
      With H2-histamine receptor blockers, propranolol, atenolol, cefdinir, cefpodoxime, metoprolol, chloroquine, prostacyclins, diflunisal, digoxin, bisphosphonates, ethambutol, isoniazid, fluoroquinolones, sodium fluoride, glucocorticosteroids ( nisolone and dexamethasone), indomethacin, ketoconazole , lincosamides, phenothiazine antipsychotics, penicillamine, rosuvastatin, iron salts, levothyroxine.
      When taken simultaneously with Maalox®, the absorption of the above drugs in the gastrointestinal tract is reduced. In the case of a 2-hour interval between taking these drugs and Maalox® and a 4-hour interval between taking fluoroquinolones and Maalox®, in most cases this undesirable interaction can be avoided.
      With polystyrene sulfonate (kyexalate)
      When Maalox® is co-administered with polystyrene sulfonate (kyexalate) caution should be exercised because of the possible risk of reducing the efficiency of potassium binding by the resin and the development of metabolic alkalosis in patients with renal insufficiency (for aluminum hydroxide and magnesium hydroxide) and bowel obstruction (for aluminum hydroxide).
      With citrates
      The combination of aluminum hydroxide with citrates may increase the plasma concentrations of aluminum, especially in patients with renal insufficiency.

      Indications for use

      – Peptic ulcer of the stomach and duodenum in the acute phase. – Acute gastroduodenitis, chronic gastroduodenitis with normal or increased secretory function in the acute phase. – Hernia of the esophageal opening of the diaphragm, reflux esophagitis. – Dyspeptic phenomena such as epigastric discomfort or pain, heartburn, sour eructation after dietary errors, excessive consumption of ethanol, coffee, nicotine, etc. Dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, acid belching (and their prevention), resulting from the use of certain drugs (non-steroidal anti-inflammatory drugs, glucocorticosteroids, etc.).

      Manufacturer

      Sanofi S.p.A.

      INN / Active ingredient Dose

      400 mg + 400 mg

      Presentation

      Chewable tablets

      Quantity per pack Composition Method of preparation Special conditions Side effects Contraindications Storage conditions Shelf life Minimum age Partner

      Pharmacy DIALOG Capital

      This product can be supplied by several manufacturers at once. For this reason, the information is different. Data corresponding to a particular product is always presented on the label. The appearance of the product in the store may also differ from the image in the photo.

      Pharmaceutical partner licenses

      Show availability in stores

      Comparison of oral cephalosporins: microbiology and common ground

      Author:
      Head of the Department of Hospital Pediatrics of the Zaporozhye State Medical University, Doctor of Medical Sciences, Professor G. A. Lezhenko

      03.10.2019

      PDF article

      According to the World Health Organization (WHO), antimicrobial resistance is a significant public health problem worldwide. It threatens effective prevention and successful treatment of the growing number of infections caused by bacteria, parasites, viruses and fungi. Routine surgical interventions and banal infectious diseases will again become dangerous for human life due to the rapid emergence and spread of drug-resistant supermicrobes in the world. According to experts, in the US and Europe alone, antimicrobial-resistant infections currently lead to 50,000 deaths per year, and more than 100,000 people die annually in other regions of the world from pathogenic microflora insensitivity to existing antibiotics. If the progression of antibiotic resistance is not slowed down, the consequences will be even worse. Therefore, a report on the rational use of cephalosporins in the context of global antibiotic resistance, presented at the scientific and practical conference with international participation “Innovations in pediatric gastroenterology and nutrition in the practice of a pediatric and family doctor” in Kharkiv by the head of the Department of Hospital Pediatrics of the Zaporozhye State Medical University, Doctor of Medical Sciences , Professor Gennady Alexandrovich Lezhenko caused a huge resonance among clinicians.

      – About 700-800 tons of antibiotics are used annually in the world. Antimicrobials, especially their oral forms, are predominantly prescribed in outpatient practice. Most often, antibiotics are used for pathology of the respiratory tract (on average 50-70% of total consumption), diseases of the genitourinary system and intestinal infections. Community use of antibiotics accounts for 2/3 of their global turnover. Due to the excessive and irrational use of antimicrobial drugs in medicine, veterinary medicine, and the agricultural industry, pathogenic microflora become resistant to their effects. According to an independent review of antimicrobial resistance, by 2050, if appropriate measures are not taken, infections caused by antibiotic-resistant pathogens could kill 10 million people a year, which is more than from cancer and diabetes combined currently.

      Due to the emergence of a large number of resistant strains of microorganisms, the pharmaceutical industry is eager to supply new antibiotics. However, according to the latest data, most of the drugs currently under clinical development are modifications of already existing classes of antibiotics, in fact, generics. At the same time, the number of new, first synthesized antimicrobial molecules is rapidly decreasing. So, for 1983-1987gg. 16 original antibiotics were developed, from 1998 to 2002. only 7 were created, in 2003-2007. Only 4 new medicines have been officially registered. Against the backdrop of a decrease in the number of innovative antibiotic molecules, the importance of important groups of drugs has practically been lost: tetracyclines, early cephalosporins, co-trimoxazole, etc. Only a few drugs can potentially be used to treat antibiotic-resistant infections.

      Mechanisms for the formation of resistance of pathogenic microflora to the effects of one or more antibacterial agents are diverse. Currently, natural and acquired resistance are distinguished. True natural resistance is a constant species characteristic of pathogens, is easily predicted and is characterized by the absence of a target for the action of an antibiotic in microorganisms or its inaccessibility due to the initially low permeability of the microbial cell or enzymatic inactivation. If bacteria have natural resistance, antibiotics are clinically ineffective. Acquired resistance is understood as the property of individual strains of microorganisms, as a result of obtaining new genetic information or changing the level of expression of their own genes, to remain viable at those concentrations of antimicrobials that usually suppress the bulk of the microbial population. The resistant strain formed in this way is further capable of rapid intra- and interspecific horizontal transfer of drug resistance genes.

      The main reasons for the spread of resistant bacteria in the world are the low level of hygiene, the use of antibiotics without indications, their prescription without taking into account data on local resistance, incorrect doses and duration of treatment, uncontrolled use in various fields of activity (more than 50% of antibiotics in the world are not used in medicine).

      The problem of antibiotic resistance is multifaceted, so WHO has developed a strategic action plan to address it, which provides for an in-depth study of antimicrobial resistance, infections caused by pathogens that are not sensitive to antibiotics, including through effective epidemiological surveillance, reducing the incidence, optimizing the use of antibiotics, increasing investment in the development of new medicines, vaccines, diagnostic tools.

      One of the important steps in the elimination of drug resistance is dynamic bacterial monitoring to decipher the type of pathogen, assess local antibiotic and phage resistance, make an informed decision regarding treatment and antibiotic prophylaxis. It is well known that the main causative agents of bacterial infectious diseases of the upper respiratory tract are pneumococcus, Haemophilus influenzae, Moraxella, Streptococcus, Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacteria, Mycoplasma, Chlamydia (D.N. Gilbert et al., 2012). In the structure of pathogens of urinary tract infections in children, according to the data of the European Association of Urology for 2013, E. coli (56.7%), then Proteus (8.5%), Enterococcus (8.5%), Klebsiella pneumoniae (8.0%), Enterobacter cloacae (5.7%), Pseudomonas aeruginosa (5.4%). However, every year there is a change in the microflora and the frequency of occurrence of pathogenic microorganisms. So, in a comparative analysis of the most common bacterial pathogens of respiratory infections in children in 2017, a significant decrease was found compared to 2014. Haemophilus influenzae, H. haemolyticus in the development of respiratory diseases against the background of an increase in the proportion of S. pneumoniae, K. pneumoniae, M. catarrhalis. Isolation frequency of H. influenzae in children with tonsillopharyngitis, rhinosinusitis, acute bronchitis, pneumonia in 2014 and 2017 also had significant differences. In recent years, in the etiological structure of pathogens of acute and chronic urinary tract infections, there has been a significant decrease in the traditional role of E. coli , the 2nd place in prevalence was occupied by enterococci ( E. faecalis and E. faecium ), which in some cases explains the ineffectiveness of empirical antibiotic therapy (own data).

      In the context of the rational use of antibiotics in global antibiotic resistance, accurate diagnosis, identification of pathogenic microflora, reliable data on local susceptibility of pathogenic bacteria, understanding of the clinical efficacy of antimicrobials, including safety, pharmacokinetics, pharmacoeconomics and dosage forms of drugs, assessment of the severity of the condition, the need for eradication. Unfortunately, in Ukraine there is no national register of local resistance of microorganisms, so clinicians are forced to rely on international data.

      When choosing a drug for empirical antibiotic therapy, it is necessary to give preference to such a drug that affects both gram-positive and gram-negative microflora. In this aspect, cephalosporins deserve the attention of clinicians. To date, there are five generations of cephalosporins. Currently, fifth-generation cephalosporins are not used in children. The use of IV generation cephalosporins in outpatient practice is limited due to the parenteral form of release.

      The main feature of the 1st generation cephalosporins is their high antistaphylococcal activity (with the exception of MRSA), however, the bactericidal effect against some gram-negative bacteria ( E. coli, P. mirabilis ) is significantly lower than that of drugs of the II-IV generations. I generation cephalosporins do not act on enterococci, listeria, salmonella, shigella, H. influenzae and M. catarrhalis are resistant to them; in terms of the level of influence on S. pneumoniae, they are significantly inferior to aminopenicillins. Therefore, 1st generation cephalosporins cannot serve as the drugs of choice for the treatment of respiratory pathology. II generation cephalosporins do not differ in their effect on gram-positive cocci from those of the first generation, however, they show higher activity against gram-negative bacteria ( H. influenzae, M. catarrhalis, E. coli , some strains of Klebsiella, Proteus).

      III generation cephalosporins have a broad spectrum of activity against many gram-positive, gram-negative, aerobic and anaerobic microorganisms, including some nosocomial multidrug-resistant strains. They are presented in parenteral and oral forms of release, which makes it possible to successfully use these drugs in a hospital and on an outpatient basis. The active ingredients of oral cephalosporins of this generation are cefixime trihydrate and cefpodoxime proxetil.

      ! In accordance with the official annotation, both drugs have a similar effect on the same pathogenic microflora. However, according to the latest European Committee on Antimicrobial Susceptibility Testing (EUCAST) data, cefixime has virtually no effect on S. pneumoniae, unlike cefpodoxime.

      Also, cefpodoxime exhibits 2.5 times greater activity than cefixime against Haemophilus influenzae, 5 times against Moraxella and several hundred times against pneumococcus. Therefore, cefpodoxime is the most effective drug for the treatment of pulmonary pathology among third-generation oral cephalosporins. Indications for the use of cefixime – diseases of the urinary system caused by E. coli . It has been proven that a standard dose of cefixime creates a drug concentration in the urine 650 times higher than necessary for the eradication of this pathogen.

      In Ukraine, for successful treatment in pediatric practice of infections of the respiratory and urinary system, high-quality and effective 3rd generation cephalosporins from the leading Jordanian biopharmaceutical corporation Pharma International Company – Cefodox and Cefix are used. Cefodox (cefpodoxime) is available in the form of a powder for the preparation of an oral suspension of 50 and 100 mg/5 ml in 50 ml vials (approved for use in children from 5 months of age) and film-coated tablets of 100 and 200 mg (for adults). and children over 12 years of age). For children aged 5 months to 12 years, the drug is prescribed at a dose of 10 mg/kg of body weight per day (maximum daily dose is 400 mg). The duration of treatment depends on the severity of the disease and is determined individually. The prepared suspension of Cefodox is taken with meals to enhance the bioavailability of the drug. Cefix (cefixime) is presented in the form of a powder for the preparation of 30 and 60 ml of oral suspension of 100 mg/5 ml (for children from 6 months) and capsules of 400 mg (for adults and children over 12 years of age weighing more than 50 kg). The recommended dose of Cefix for children aged 6 months to 10 years weighing up to 50 kg is 8 mg/kg per day in 1 dose or 4 mg/kg every 12 hours, depending on the severity of the disease.

      Thus, each antibiotic has its own point of application, the empirical choice of an antimicrobial agent does not mean random prescription, but must meet the criterion of “prescribed on the basis of experience”. Due to the peculiarities of pharmacokinetics, pharmacodynamics and the spectrum of antimicrobial effects, cefpodoxime (Cefodox) is an effective tool for the treatment of bacterial respiratory pathology, and cefixime (Cefix) is an infection of the urogenital tract in children.

      Prepared Victoria Bandaletova

      Thematic issue “Pediatrics” No. 3 (50), 2019

      • Number:
      • Thematic issue “Pediatrics” No. 3 (50), 2019

      06/15/2023

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      Hypoxic-ischemic encephalopathy (HIE) is one of the most widespread and serious neurological conditions that are blamed on newborns and children of the early age. It is the fault of the hemorrhaging of that acidic starvation of the brain, which leads to the destruction of the energy exchange in the neuronal cells. Understanding the pathophysiological mechanisms associated with energy metabolism may be key to developing effective strategies for metabolic correction….

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      Allergic disease is a significant burden for sick children, their families and ailments. In clinical practice, pediatricians often suffer from allergic rhinoconjunctivitis (AR) and kropivyanka. The symptoms that accompany illness can disrupt sleep patterns and interfere with daily activities, lead to emotional stress and behavioral problems, which are badly spilling over into training. …

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      Radiation hazard was the basis for the onset of vindication of nuclear power plants.