COREG CR® Home – Coreg CR® (carvedilol phosphate) Extended Release Capsules

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3 Steps to Getting Brand-Name COREG CR

At Your Doctor’s Office:

Ask your doctor to write “COREG CR” and “Dispense As Written – DAW” on the prescription.

Get Your Savings Card:

COREG CR Savings Card

At The Pharmacy:

Show the Pharmacist your Savings Card and be sure the bottle says “COREG CR”

What is Once-Daily COREG CR?

COREG CR is a once-a-day heart medication that is part of a class of drugs known as beta-blockers. COREG CR treats people who have or had one or more of the following: high blood pressure, also known as hypertension, heart failure, and/or a heart attack that reduced how well the heart pumps.

If you have been diagnosed with heart failure or have had a heart attack that reduced how well your heart pumps, COREG CR can strengthen your heart and provide daily cardio-protection. *

*The studies showing heart benefits were done with COREG®. COREG CR contains the same active ingredient as COREG.

COREG CR for High Blood Pressure

High blood pressure is a serious risk factor and should be treated as such. It is also known as hypertension and is a relatively common condition.

If you have high blood pressure, your heart is working harder than it should, putting you at risk for heart failure or a heart attack. Lifestyle changes alone may not be enough to take the strain off your heart.

COREG CR is a beta-blocker, which is a class of drugs that has been proven to lower your blood pressure. COREG CR contains the same active ingredient as Coreg® (carvedilol). COREG was found in the GEMINI study to be a good option if you have high blood pressure and other risk factors such as high cholesterol or high blood sugar because it had no negative impact on blood sugar levels or cholesterol.

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COREG CR for a Heart Attack that Reduced How Well Your Heart Pumps

If you’ve had a heart attack that reduced how well your heart pumps, you are probably worried about your health. But many people who have had a heart attack that reduced how well your heart pumps recover and are able to enjoy life as they did before.

COREG CR can help improve your heart health. Adding COREG CR to your current therapy could help prevent another heart attack.

Learn more about what a heart attack is and what puts you at risk. It also tells you how to take steps to improve your heart health.

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COREG CR for Heart Failure

Many people do not know what heart failure is—only that it sounds scary. In fact, it is a serious and chronic condition that can severely affect your health. The good news is that heart failure, if diagnosed, can be managed. Through a combination of COREG CR and lifestyle changes, many people can start to live healthier lives.

If you have heart failure, COREG CR can help. COREG CR is in the class of drugs called beta-blockers, and is approved by the FDA for the treatment of mild, moderate, or severe heart failure. It helps to lower the heart rate and make the heart pump better. COREG CR is proven to help people with heart failure live longer and stay out of the hospital.

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Taking Control of Your Heart Health Plan

Talking with Your Doctor ›

Taking COREG CR ›

Coreg or Coreg CR: Carvedilol

Content

• What is carvedilol?
• What does carvedilol treat?
• How do you take carvedilol?
• Seeing results of carvedilol
• Potential side effects of carvedilol
• Long-term use of carvedilol
• Missed doses
• Overdoses
• What to discuss with your doctor before taking carvedilol
• Stopping carvedilol
• Carvedilol and pregnancy
• Carvedilol and interactions with other drugs
• Carvedilol allergy information
• Clinical trial history of carvedilol

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Doctors prescribe carvedilol to people who have hypertension (high blood pressure). Carvedilol also prevents episodes of stroke, heart attack, and heart failure. 

Carvedilol belongs to a class of drugs called beta-adrenergic blocking agents, also known as beta-blocking agents, or more commonly, beta-blockers.
Beta-blockers work by affecting the response of nerves to certain stimuli. As a result, this prescription drug helps lower the heart’s workload by reducing the demand for blood and oxygen.
Carvedilol also relaxes blood vessels by blocking alpha receptors, lowering blood pressure. It also slows the heart rate by blocking the action of certain hormones, like adrenaline.

How To Lower High Blood Pressure: Science-Backed Methods That Can Help

Carvedilol is the generic drug name for the brand Coreg or Coreg CR (Extended-Release).

Doctors prescribe carvedilol to people at risk for or with a history of:

• Hypertension 

• Heart disease

• Heart attacks

• Stroke 

In addition, carvedilol is prescribed with other drugs to treat heart failure or prevent chest pain due to angina (reduced blood flow to the heart). Doctors may also prescribe carvedilol to those with atrial fibrillation (a-fib), which is a certain type of irregular heartbeat.

Your doctor will prescribe carvedilol based on your individual needs. They may increase or decrease the dosage as needed. Always speak with your doctor before making any changes to your medication regimen.

 Carvedilol is available in the following dosages and forms:

• Tablet (3.125mg, 6.25mg, 12.5mg, 25mg)

• Extended-ReleaseCapsule (10mg, 20mg, 40mg, 80 mg)

For hypertension

Immediate-Release

• An initial dose of 6.25 mg, taken orally, twice daily

• After seven to 14 days, it could be increased, as tolerated, to 12.5mg, twice daily, then 25mg, twice daily 

Extended-Release

• An initial dose of 20mg, taken orally, once daily for one to two weeks

• The subsequent dose could be increased to 40mg, once daily, as needed

• Dosage should not exceed more than 80mg per day

For congestive heart failure

Immediate-Release

• An initial dose of 3. 125mg, taken orally every 12 hours for two weeks

• The subsequent dose could be increased every two weeks, as tolerated, to 6.25mg, 12mg, or 25mg, twice daily

• The maximum dosage could be 25mg, taken orally, twice daily

Extended-Release

• An initial dose of 10mg, taken orally, once daily, for one to two weeks

• The subsequent dose could be increased to 20mg per day, 40 mg per day, or 80 mg per day, as needed

For left ventricular dysfunction (LVD) following a heart attack

Immediate-Release

• An initial dose of 3.125mg to 6.25mg, taken orally every 12 hours

• After 3–10 days, it could be increased as tolerated, first to 12.5mg every 12 hours, and then to 25mg every 12 hours

Extended-Release

• An initial dose of 10–20 mg, taken orally, once, daily

• It could be increased every 3-10 days, as tolerated, up to 80mg daily

For angina pectoris

Immediate-Release

Carvedilol typically starts to work within two hours of taking it.

If you are using carvedilol to treat hypertension, it usually takes about seven days to get results. You may not notice a difference at first, but that doesn’t mean the medication isn’t working.

Common side effects of carvedilol include:

 Rare side effects of carvedilol include:

• Raynaud’s phenomenon (reduced blood flow to fingers)

• Impotence

• Depression

• Insomnia

• Skin rash

• Bronchospasm (tightening of the airways)

• Severe allergic reaction

Doctors prescribe carvedilol for both short-term and long-term use. Those who take carvedilol for health maintenance may need to take it for life.

If you miss a dose of carvedilol, take it as soon as you remember. However, do not take it within six hours of your next scheduled dose. If you are too close to the timing of the next dose, skip it and take the next dose as planned. Try to take your medication on a regular schedule and avoid missed doses.

If you accidentally take too much carvedilol, you might experience the following side effects:

How To Lower High Blood Pressure: Science-Backed Methods That Can Help

• Low blood pressure

• Slow heart rate

• Vomiting

• Fainting

• Seizures

• Heart attack

• Trouble breathing

If you know or suspect that you have exceeded your prescribed amount of carvedilol, call 911 or seek immediate medical attention.

 Here are some of the topics to discuss with your doctor before taking carvedilol:

• Allergies you have or past allergic reactions to medications (especially carvedilol or other beta-blockers). 

• Medications you are currently taking (prescribed or non-prescribed), including vitamins and supplements you take (or plan to take).

• Existing health conditions, like diabetes, hyperthyroidism, liver disease, asthma, Prinzmetal’s angina, or pheochromocytoma.

• Circulatory (blood flow) problems in your legs and feet. 

• Whether you are pregnant or trying to get pregnant. 

• Whether you are currently breastfeeding or planning to breastfeed. 

• Upcoming medical or dental procedures (or plans to have one). 

• Whether or not you consume alcohol, how much, and how frequently.

• Your career, lifestyle, and hobbies. Some side effects of carvedilol may prevent you from certain activities, such as driving. 

• Suitability of wearing contact lenses (dry eyes are a side effect of taking carvedilol). 

• Appropriate dietary and exercise regimens that are suitable while using carvedilol to treat hypertension (if applicable).

Always speak with your doctor before stopping carvedilol.
Suddenly stopping carvedilol can cause serious issues, including severe chest pain, high blood pressure, irregular heartbeat, or heart attack.

 If your doctor determines that it’s appropriate to take you off of carvedilol, they will monitor you closely for several weeks.  You will likely be advised to slowly wean down the dose rather than stop this medication abruptly unless you are having severe side effects.

There is insufficient data on the safety of carvedilol’s use in pregnant women or the risks it may pose to unborn children.

Be sure to speak with your doctor about carvedilol’s suitability if you are pregnant or planning on becoming pregnant.
If you are taking carvedilol while pregnant, your doctor will likely advise you to stop taking it at least two or three days before the expected birth.
Carvedilol can pass from mother to child through breastfeeding.

Carvedilol falls into what was previously called Category C, meaning that risk to the fetus is possible.¹ The risks vs. benefits of carvedilol use during pregnancy should be discussed directly with your physician, who will determine if you should continue this medication.
Typically, carvedilol should not be stopped abruptly. More commonly, it is weaned down slowly with decreasing doses over one to two weeks.  You should follow the instructions given to you by your physician which are specific to your particular medical profile.

Drugs that may interact with carvedilol and cause unwanted side effects include:

• Beta-blockers
  Acebutolol (Sectral), atenolol (Tenormin), bisoprolol (Concor), metoprolol (Lopressor), and propranolol (Inderal) should not be used with carvedilol, as it could cause low blood pressure or reduced heart rate.

• Diabetes medication
  When taken with carvedilol, insulin injections and oral medication for diabetes may increase the risk of low blood sugar levels.

• Cyclosporine
  Taking carvedilol with the organ transplant rejection drug cyclosporine (Gengraf, Neoral, or Sandimmune) could increase your level of cyclosporine.

• Clonidine
  Taking carvedilol with the blood pressure medication clonidine (Catapres) could significantly lower your blood pressure and heart rate.

Severe allergic reaction, also known as anaphylaxis is rare, but a possibility for those who take carvedilol. Symptoms of anaphylaxis include:

If you experience symptoms of a severe allergic reaction, seek immediate medical help or call 911.

Carvedilol was developed to treat congestive heart failure. It has gone through four clinical trials in the US, and one in Australia/New Zealand. Carvedilol received FDA approval in 1995.

Tips and advice for taking carvedilol:

• Take carvedilol at the same time every day.

• Always take carvedilol with food to reduce the risk of a drop in blood pressure from suddenly standing up, sitting, or lying down.

• When sitting up or lying down, do so slowly to avoid dizziness.

• Check your blood pressure at least twice per day, especially when starting to take carvedilol. Inform your doctor if your condition hasn’t improved after a week.

• If you have diabetes, frequently monitor your blood sugar while taking carvedilol.

• Avoid driving, using machinery, or doing activities that require full attention. Carvedilol may cause dizziness.

• Avoid drinking alcohol within two hours before or after taking this drug.

• Never switch from immediate-release to extended-release Carvedilol without guidance and approval from your doctor.

• Follow your doctor’s recommendations for diet and exercise.

• Keep carvedilol away from moisture and heat. Store it at room temperature.

Corega Product Overview: Helping Patients Wearing Dentures

Corega Product Overview: Designed to keep dentures functional with daily use

Transitioning from natural teeth to dentures can be difficult, and often the expectations of denture use are unrealistic. ^1.2

Corega’s range of denture care products helps patients maintain optimal function and hygiene of their dentures.

Corega Denture Adhesive Cream ³

• More effective fixation of dentures
• Prevent food particles from getting under the denture

Corega Denture Cleaner Tablets ³

• Biofilm Reduction*
• Reduction of potentially harmful bacteria and fungi*

*vs soaking in water

Factors affecting the functionality of dentures

• Up to 48% of denture wearers experience dry mouth* ⁴
• Up to 67% of patients wearing complete dentures report denture-induced stomatitis ⁵

*In a study by Takayama et al. 2005

• Up to 86% of denture wearers complain of food particles getting under their dentures ⁶

• Over 80% of denture wearers clean their dentures with regular toothpaste ^7.8
• Nearly 63% of patients wearing full dentures have biofilm and tartar on dentures ^†9

^† In an observational study

Benefits of using Corega products: despite a good denture fit, patients may experience problems with the functionality and hygiene of the denture

• Lyudmila, 41 years old, with peculiarities of the anatomical structure of the oral cavity

  With peculiarities of the anatomical structure of the oral cavity

  Complaints: “The dentures constantly slip off, especially when eating. I can’t be sure if they will last all day.”

  After starting to use Korega denture fixation cream: “Using the cream keeps the dentures in place. Now when I have lunch with colleagues, I feel much more confident.”

  All examples and quotations are fictitious and are provided for illustrative purposes only

• Petr, aged 68, has problems with dry mouth

  Has problems with dry mouth

  Complains: “Often my dentures move, chafing my gums. Dentures hit lips, cheeks and tongue – very annoying.”

  After using Corega Denture Fixation Cream: “A little fixation cream before starting to use dentures, and I no longer worry about denture shifting, which irritated me so much. Now they are securely fixed”

  All examples and quotations are fictitious and are provided for illustrative purposes only

• Elena, aged 45, has trouble adjusting to dentures

  Cannot get used to dentures

  Complaints: “When something small and hard gets into the space between the denture and the gum, for example, a particle of potato chips, it feels like eating nails. Also, my dentures fall out…”

  After using Corega denture fixation cream: “With denture fixation cream, I can eat whatever I want”

  All examples and quotations are fictitious and are provided for illustrative purposes only

• Larisa, aged 55, pays insufficient attention to dental prosthesis hygiene

  Pays insufficient attention to dental prosthesis hygiene

  Complaints: “Very disturbing breath and bad breath. During a conversation, I have to keep a distance from the interlocutor. The smell from my mouth also affects my intimacy with my husband”

  After using Corega Denture Cleansing Tablets: “Now I know I am providing the best possible care for my dentures, so I feel confident enough to communicate without fear.”

  Disclaimer: All incidents and quotes are fictitious and shown for illustration purposes only

• Konstantin, aged 48, suffers from prosthetic stomatitis

  Suffering from denture stomatitis

  Complaints: “Honestly, I have never bothered to take care of my teeth, so now I also have a hard time making myself think about cleaning my dentures. ..”

  After using Corega denture cleaning tablets: “Now I just drop tablet in a glass of water, soak the denture overnight – and that’s it, it’s done”

  All examples and quotations are fictitious and are for illustration purposes only

Find out what technologies are used in Corega 9 products0003

Corega Denture Adhesive CreamCorega Denture Adhesive Cream is designed to stabilize, hold and maintain the functionality of dentures. ^10.11

Corega Denture Cleaner TabletsCorega Denture Cleaner Tablets contain four active ingredients that work together to keep dentures clean with minimal scratches. ^12.13

Explore our educational resources for oral care and dentures.

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Corega Denture Fixing and Cleaning Line

Corega Denture Adhesive Cream

Helping patients maintain the functionality of their dentures with daily use.

Denture Cleaner Tablets Corega

Helps patients keep their dentures clean with daily use.

Corega Tablets Daily Cleansing Caps & Retainers

Helping patients maintain proper hygiene of their orthodontic appliances in daily use.

Learn more about Corega products

Denture care

Learn more about denture care

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Adverse event reports

If you became aware of adverse events that occurred during the use of GSK drugs please let us know by email or phone.

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Materials for patients

Download materials for your patients

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KOREGA – Buy in Ukraine | Price from 117.00 UAH

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Editorial group

Creation date: 04/27/2021
Update date: 06/22/2023

The Secret of Inspired Laughing – Corega

Corega products are manufactured in Ireland at the Stafford Miller plant, which is home to the international pharmaceutical company GlaxoSmithKline (GSK).

Corega products are represented by products for dentures:

• fixation cream;
• cleaning tablets.

Peculiarities of Corega 9 cream0003

Corega’s fixation cream has daily zinc, so it’s safe and suitable for regular fixation. To this warehouse enter:

• podvyna sil gantrez (prepared with sodium and calcium) – the main component, which ensures safe fixation;
• gum arabic – resin of natural origin, vicory to strengthen power;
• mineral oil – allows you to spread evenly;
• special barvniki – brewing cream in the color is clear.

Cream Corega may ADHESIVE-enveloping power and fixing the prosthesis with a stretch of 12 years. Vіn zapovnyuє empty expanse between them and clear, blowing like a shock absorber. Also, the cream does not allow the prosthesis to be eaten by parts of the hedgehog.

Three types of Corega cream are produced with the same fixation strength:

Refreshing relish – breathes under the air in the place of mint, which ensures the additional freshness of the soul.

Corega Cleansing Tablets – a clear look after dentures

To keep the dentures safer, without looking bad, it is necessary to clean them with care without abrasive ingredients. Vіd zvichaynoї dentifrice on the new one there will be micro-scratches.

Corega Cleansing Tablets provide a quick look at your dentures. Їх prices for 15 credits:

• cash;
• harboring micro-organisms that produce an unpleasant odour;
• deodorant with minty freshness.

Corega cleansing tablets come in two varieties:

In the pharmacy store 9-1-1, products of the Corega trademark are still in evidence. Reach out to us!

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