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Does dmso work. DMSO for Arthritis: Efficacy, Risks, and Medical Uses Explored

by alexxlab

What are the potential benefits and risks of using DMSO for arthritis. How does DMSO work in the body. Is DMSO FDA-approved for treating arthritis. What are the approved medical uses for DMSO. What precautions should people take when considering DMSO as a treatment.

Understanding DMSO: Origins and Properties

Dimethyl sulfoxide (DMSO) is a clear, odorless liquid that has gained attention in recent years for its potential medicinal properties. Originally a byproduct of the paper-making process, DMSO was primarily used as an industrial solvent. However, in the 1960s, scientists discovered its unique ability to penetrate biological membranes rapidly, opening up new possibilities in medicine.

What makes DMSO special? Its molecular structure allows it to easily pass through cell membranes, including the skin. This property has led to its use as a vehicle for delivering topical medications more effectively. Additionally, DMSO itself is believed to have pain-reducing and anti-inflammatory properties, which has fueled interest in its potential as a treatment for various conditions, including arthritis.

DMSO and Arthritis: Exploring the Claims

Can DMSO effectively treat arthritis symptoms? While anecdotal evidence suggests that DMSO may help reduce pain and inflammation associated with arthritis, it’s crucial to note that the Food and Drug Administration (FDA) has not approved DMSO or any DMSO-derived ingredients for arthritis treatment.

Why do some people believe DMSO works for arthritis? The substance’s purported anti-inflammatory properties and its ability to penetrate deeply into tissues may contribute to perceived benefits. However, it’s important to distinguish between anecdotal claims and scientific evidence. Currently, the support for DMSO as an arthritis treatment is largely based on personal experiences rather than rigorous clinical studies.

The Importance of Medical Guidance

Should individuals try DMSO for arthritis without consulting a doctor? Absolutely not. Given the lack of FDA approval and potential risks, it’s crucial for anyone considering DMSO as an arthritis treatment to consult with a healthcare professional first. A doctor can provide personalized advice, discuss potential risks and benefits, and suggest FDA-approved alternatives that may be more suitable and safer.

Potential Risks and Side Effects of DMSO

What are the known side effects of DMSO use? A comprehensive 2018 review of 109 studies reported various adverse reactions to DMSO, ranging from mild to severe:

  • Gastrointestinal symptoms: halitosis, abdominal aches, stomach cramps, nausea, vomiting, and diarrhea
  • Dermatological reactions: rashes, itching, scaling, blistering, and increased skin pigmentation
  • Rare cardiac and neurological reactions

How do the administration method and dosage affect side effects? The review indicated that the method of DMSO administration could influence the type of side effects experienced. For instance, cardiac reactions were only observed with intravenous administration, while skin reactions were more common with topical applications. Additionally, the severity of side effects appeared to be dose-dependent, with low doses generally resulting in no or mild side effects.

Drug Interactions and Absorption Concerns

Why is DMSO’s ability to enhance absorption a double-edged sword? While this property makes DMSO an effective carrier for other medications, it also presents risks. Using DMSO in combination with other topical medications could lead to dangerously increased absorption of those drugs into the body. This potential for drug interactions underscores the importance of medical supervision when considering DMSO use.

FDA-Approved Uses of DMSO

What is the only FDA-approved use for DMSO? Currently, the FDA has approved DMSO solely for the treatment of interstitial cystitis, a chronic bladder condition characterized by pain and pressure. This limited approval highlights the need for further research into DMSO’s efficacy and safety for other conditions, including arthritis.

How is FDA-approved DMSO typically administered? The most common methods of administration for approved uses are topical (as a gel or solution) and intravesical (through the bladder). Other methods, such as oral and intravenous administration, lack sufficient research to determine their safety and efficacy.

DMSO in Cancer Treatment: A Complex Picture

What role does DMSO play in cancer treatment? The relationship between DMSO and cancer treatment is complex and still not fully understood. Some studies suggest that DMSO may offer relief from certain chemotherapy side effects, such as skin and tissue damage. However, its use in cancer treatment is not straightforward and can carry risks.

How can DMSO interact with chemotherapy drugs? A 2014 study revealed that DMSO could interfere with the effectiveness of certain chemotherapy drugs, including cisplatin, carboplatin, and oxaliplatin. This interference could potentially reduce the efficacy of cancer treatments.

Are there any potential benefits of DMSO in cancer research? Interestingly, a more recent 2020 study indicated that DMSO might have anti-cancer properties, potentially preventing the growth of cancer cells and encouraging their death. This conflicting information underscores the need for further research to fully understand DMSO’s role in cancer treatment.

FDA-Approved DMSO-Containing Cancer Treatment

Is there an FDA-approved cancer treatment containing DMSO? Yes, the FDA has approved trametinib dimethyl sulfoxide, a combination of trametinib and dimethyl sulfoxide, for treating specific types of cancer under certain conditions. This treatment is indicated for anaplastic thyroid cancer, melanoma, and non-small cell lung cancer, but only when the patient and the cancer meet specific criteria.

The Current State of DMSO Research

What is the current scientific consensus on DMSO for arthritis treatment? While anecdotal evidence suggests potential benefits, there is currently insufficient scientific evidence to prove that DMSO is both safe and effective as an alternative treatment for arthritis. The lack of rigorous clinical trials and FDA approval for this use means that more research is needed before DMSO can be recommended as a reliable arthritis treatment.

Why is more research needed on DMSO? The complex nature of DMSO’s interactions with the body and other medications, along with its potential benefits and risks, necessitates further study. Comprehensive clinical trials are required to establish its efficacy, optimal dosing, and long-term safety profile for conditions like arthritis.

Precautions and Considerations for DMSO Use

What precautions should individuals take when considering DMSO use? Given the current state of research and potential risks, several precautions are essential:

  1. Consult a healthcare professional: Never use DMSO without first discussing it with a doctor, especially if you have existing health conditions or are taking other medications.
  2. Use only as prescribed: If DMSO is recommended by a healthcare provider, use it exactly as directed and for the approved purpose only.
  3. Be aware of potential side effects: Familiarize yourself with the possible adverse reactions and report any unusual symptoms to your doctor immediately.
  4. Avoid self-medication: Do not attempt to treat arthritis or any other condition with over-the-counter or industrial-grade DMSO products.
  5. Consider FDA-approved alternatives: Discuss FDA-approved arthritis treatments with your healthcare provider, as these have undergone rigorous testing for safety and efficacy.

How can individuals protect themselves from potentially harmful DMSO products? Only use DMSO products that are specifically approved for medical use and obtained through legitimate healthcare channels. Avoid purchasing DMSO from unregulated sources or using industrial-grade DMSO for medicinal purposes, as these may contain impurities or incorrect concentrations that could be dangerous.

The Future of DMSO Research

What areas of DMSO research show promise? While current evidence for DMSO in arthritis treatment is limited, ongoing research continues to explore its potential in various medical applications. Areas of interest include:

  • Pain management in other conditions
  • Enhancing drug delivery for various treatments
  • Potential neuroprotective properties
  • Applications in regenerative medicine

How might future research impact DMSO’s medical use? As more rigorous studies are conducted, we may gain a clearer understanding of DMSO’s mechanisms of action, optimal dosing, and potential applications. This could lead to new FDA-approved uses or, conversely, further restrictions on its use if significant risks are identified.

The Role of Clinical Trials

Why are clinical trials crucial for DMSO research? Clinical trials provide the structured, controlled environment necessary to evaluate DMSO’s efficacy and safety thoroughly. These studies can help determine appropriate dosages, identify potential side effects, and compare DMSO’s performance against existing treatments. Only through such rigorous scientific investigation can DMSO’s true potential as a medical treatment be realized and validated.

How can individuals stay informed about DMSO research developments? Those interested in DMSO’s potential medical applications should:

  • Regularly consult reputable medical sources and journals for updates on DMSO research
  • Discuss new findings with healthcare providers to understand their relevance to individual health situations
  • Be cautious of sensationalized claims and always prioritize evidence-based information

As research into DMSO continues, it’s crucial to approach its potential benefits with a balanced perspective, acknowledging both its promise and the current limitations in our understanding. While DMSO may hold potential for various medical applications, including arthritis treatment, its use should always be guided by scientific evidence and medical expertise.

DMSO benefits, uses, risks, and more

While there are many arthritis treatments available, not all medications that companies market to treat the condition have approval for that purpose. One of these is dimethyl sulfoxide (DMSO).

DMSO is a clear, odorless liquid that easily penetrates the skin and other organic membranes.

It is gaining commercial traction as a potential treatment for arthritis symptoms, mostly due to its ability to reduce pain and inflammation. However, it does not have approval as an arthritis treatment.

Despite anecdotal claims of its benefits, using DMSO for arthritis, especially as an over-the-counter treatment, could be dangerous.

Read more to learn about the medical uses for DMSO, how it works, its risks and benefits, and more.

DMSO is a byproduct of the paper-making process. Originally, manufacturers used it primarily as an industrial solvent.

In the 1960s, scientists realized that DMSO could act as a way to administer topical medications. Because biological membranes can rapidly absorb DMSO, the substance can help the skin absorb medicines. It may also have pain and inflammation-reducing properties.

Probably due to its purported anti-inflammatory properties, DMSO has gained some commercial popularity as a treatment for arthritis. Some people claim that DMSO may help reduce pain and inflammation associated with the condition.

However, the Food and Drug Administration (FDA) has not approved DMSO, or any medication that includes DMSO-derived ingredients, to treat arthritis. It only has FDA approval to treat interstitial cystitis, a condition causing bladder pain.

While some research on DMSO for arthritis management may warrant further investigation, the current evidence is anecdotal rather than scientific.

With this in mind, people interested in trying DMSO for arthritis should speak with a doctor first.

In a 2018 review, researchers looked at 109 studies that reported harmful side effects of DMSO in humans. They found that most negative reactions were either short term or rare.

Some of the most common reported adverse reactions were gastrointestinal symptoms, such as halitosis, abdominal aches, stomach cramps, nausea, vomiting, and diarrhea. Other common reactions included dermatological skin reactions, such as rashes, itching, scaling, blistering, and pigmentation increases. There were also rare side effects that included cardiac and neurological reactions.

Additionally, the research indicated that side effects may have links to its administration method. For example, cardiac reactions only occurred when healthcare professionals administered DMSO intravenously, and skin reactions were more likely to develop following topical applications.

Furthermore, researchers found a connection between the dose size and reactions. People who took low doses reported no or mild side effects.

DMSO may also negatively interact with other medications. For example, because DMSO easily absorbs into the skin, using it with other topical medications could dangerously increase the amount of medication the body receives.

People interested in using DMSO for arthritis should contact a doctor before trying it or starting any new medication.

People should only use DMSO when a doctor prescribes it. The most common ways of use are topical, such as a gel or other solution, or intravesically, which involves going through the bladder.

Other methods include oral and intravenous. However, there is not enough research to determine their safety.

DMSO is also in common use as a chemical solvent in scientific and industrial communities. Medically, the only FDA-approved use for DMSO is as a treatment for interstitial cystitis, a chronic and often painful bladder condition.

There is still insufficient scientific evidence proving DMSO is both a safe and effective alternative treatment for these and other conditions.

Cancer and DMSO

While some people may experience relief from certain chemotherapy side effects, such as skin and tissue damage, using DMSO as an alternative treatment for cancer can carry risks. For example, a 2014 study explains how DMSO can interfere with chemotherapy drugs such as cisplatin, carboplatin, and oxaliplatin.

Conversely, a more recent 2020 study shows DMSO may prevent the growth of and encourage the death of cancer cells.

Furthermore, the FDA has approved trametinib dimethyl sulfoxide — a combination of trametinib and dimethyl sulfoxide — for treating anaplastic thyroid cancer, melanoma, and nonsmall cell lung cancer. However, doctors only recommend the treatment if a person and the cancer they have meet certain criteria.

At present, DMSO only has FDA approval to treat interstitial cystitis. While there is some anecdotal evidence that DMSO may alleviate the pain and inflammation associated with arthritis, there is no scientific evidence proving its efficacy.

A person interested in using DMSO for arthritis should contact a doctor.

DMSO benefits, uses, risks, and more

While there are many arthritis treatments available, not all medications that companies market to treat the condition have approval for that purpose. One of these is dimethyl sulfoxide (DMSO).

DMSO is a clear, odorless liquid that easily penetrates the skin and other organic membranes.

It is gaining commercial traction as a potential treatment for arthritis symptoms, mostly due to its ability to reduce pain and inflammation. However, it does not have approval as an arthritis treatment.

Despite anecdotal claims of its benefits, using DMSO for arthritis, especially as an over-the-counter treatment, could be dangerous.

Read more to learn about the medical uses for DMSO, how it works, its risks and benefits, and more.

DMSO is a byproduct of the paper-making process. Originally, manufacturers used it primarily as an industrial solvent.

In the 1960s, scientists realized that DMSO could act as a way to administer topical medications. Because biological membranes can rapidly absorb DMSO, the substance can help the skin absorb medicines. It may also have pain and inflammation-reducing properties.

Probably due to its purported anti-inflammatory properties, DMSO has gained some commercial popularity as a treatment for arthritis. Some people claim that DMSO may help reduce pain and inflammation associated with the condition.

However, the Food and Drug Administration (FDA) has not approved DMSO, or any medication that includes DMSO-derived ingredients, to treat arthritis. It only has FDA approval to treat interstitial cystitis, a condition causing bladder pain.

While some research on DMSO for arthritis management may warrant further investigation, the current evidence is anecdotal rather than scientific.

With this in mind, people interested in trying DMSO for arthritis should speak with a doctor first.

In a 2018 review, researchers looked at 109 studies that reported harmful side effects of DMSO in humans. They found that most negative reactions were either short term or rare.

Some of the most common reported adverse reactions were gastrointestinal symptoms, such as halitosis, abdominal aches, stomach cramps, nausea, vomiting, and diarrhea. Other common reactions included dermatological skin reactions, such as rashes, itching, scaling, blistering, and pigmentation increases. There were also rare side effects that included cardiac and neurological reactions.

Additionally, the research indicated that side effects may have links to its administration method. For example, cardiac reactions only occurred when healthcare professionals administered DMSO intravenously, and skin reactions were more likely to develop following topical applications.

Furthermore, researchers found a connection between the dose size and reactions. People who took low doses reported no or mild side effects.

DMSO may also negatively interact with other medications. For example, because DMSO easily absorbs into the skin, using it with other topical medications could dangerously increase the amount of medication the body receives.

People interested in using DMSO for arthritis should contact a doctor before trying it or starting any new medication.

People should only use DMSO when a doctor prescribes it. The most common ways of use are topical, such as a gel or other solution, or intravesically, which involves going through the bladder.

Other methods include oral and intravenous. However, there is not enough research to determine their safety.

DMSO is also in common use as a chemical solvent in scientific and industrial communities. Medically, the only FDA-approved use for DMSO is as a treatment for interstitial cystitis, a chronic and often painful bladder condition.

There is still insufficient scientific evidence proving DMSO is both a safe and effective alternative treatment for these and other conditions.

Cancer and DMSO

While some people may experience relief from certain chemotherapy side effects, such as skin and tissue damage, using DMSO as an alternative treatment for cancer can carry risks. For example, a 2014 study explains how DMSO can interfere with chemotherapy drugs such as cisplatin, carboplatin, and oxaliplatin.

Conversely, a more recent 2020 study shows DMSO may prevent the growth of and encourage the death of cancer cells.

Furthermore, the FDA has approved trametinib dimethyl sulfoxide — a combination of trametinib and dimethyl sulfoxide — for treating anaplastic thyroid cancer, melanoma, and nonsmall cell lung cancer. However, doctors only recommend the treatment if a person and the cancer they have meet certain criteria.

At present, DMSO only has FDA approval to treat interstitial cystitis. While there is some anecdotal evidence that DMSO may alleviate the pain and inflammation associated with arthritis, there is no scientific evidence proving its efficacy.

A person interested in using DMSO for arthritis should contact a doctor.

Scientists have found a way to destroy the toxic “eternal chemicals” that flooded the world – Gazeta.Ru

Scientists have found a way to destroy the toxic “eternal chemicals” that flooded the world – Gazeta.Ru | News

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Researchers have shown that a mixture of soap and DMSO solvent can break down per- and polyfluoroalkyl compounds (PFAS), known as “timeless chemicals”. Development reported Science .

Two years ago, researchers from the US Environmental Protection Agency placed a sample of PFAS in a common solvent (DMSO) to study toxicity, but the substance began to degrade. The new study builds on this observation. Scientists from Northwestern University studied various mixtures containing DMSO. The mixture of DMSO and sodium hydroxide, a common soap ingredient, showed the greatest effectiveness when heated to boiling point.

This method works with approximately 40% PFAS. Now it has to be tested on large volumes. Those compounds, the destruction of which chemists have studied, are used in fire-fighting foams and the production of non-stick coatings.

PFAS are known as “timeless chemicals” because they can remain in the environment for decades. Recently, they have even been found in rainwater in the Tibetan Plateau in quantities far exceeding safe ones. The new method will cheaply and safely cleanse the planet of potentially toxic and carcinogenic substances.

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DMSO (dimethyl sulfoxide) in the best quality pharmaceutical premium

DMSO – Universal Solvent (100 ml)

Dimethyl Sulfoxide (DMSO) is a colorless and odorless organic universal solvent used in laboratory and technical applications. Very high purity of 99.9% meets Ph.Eur certification. Depending on the application, it is easily mixed with water in any ratio. It has an amazing amount of good properties and is extremely versatile.

Benefits of using DMSO:

  • Pharmaceutical purity according to the European Pharmacopoeia

  • Integrated dropper for easy dosing

  • TÜV Rheinland tested: 100% EU-compliant

  • Filled in break-proof and child-proof HDPE bottle

  • is perfect for travel, outdoor or crisis preparedness!

  • The original, only from AQUARIUS pro life

Disadvantages compared to other DMSO solutions:

  • often no pharmaceutical safety

  • No TÜV-tested EU conformity

  • Often bottled in fragile glass bottles

  • is therefore impractical for travel and outdoor use.

Benefits of using DMSO:

  • Pharmaceutical purity according to the European Pharmacopoeia

  • Integrated dropper for easy dosing

  • TÜV Rheinland tested: 100% EU-compliant

  • Filled in break-proof and child-proof HDPE bottle

  • is perfect for travel, outdoor or crisis preparedness!

  • The original, only from AQUARIUS pro life

Disadvantages compared to other DMSO solutions:

  • often no pharmaceutical safety

  • No TÜV-tested EU conformity

  • Often bottled in fragile glass bottles

  • is therefore impractical for travel and outdoor use.

Content:

100ml 99.9% DMSO ultrapure Ph.Eur in HDPE bottle

(CAS no: 67-68-5, EC no: 200-664-3) Taric: 29091990

Storage and shelf life:

Store in a dry place at room temperature, well closed and out of the reach of children!

DMSO becomes crystalline and solid at low temperatures below 18°C, eg during transport or in winter. This is completely normal and harmless. When heated in a warm water bath, it becomes liquid again. Remove residues on fabrics and surfaces immediately with a damp cloth. DMSO is a long-term stable compound and therefore has a very long shelf life.

Areas of use:

Depending on the application, DMSO can be easily mixed with water in any ratio. Dimethyl sulfoxide has an amazing amount of good properties and is extremely versatile, being used in cosmetics, pharmaceuticals, and as a widely used solvent in laboratories and engineering, among others.

Environment protection:

The raw materials for our sustainable packaging and product information sheet come from sustainable forestry (FSC) and are printed in a climate-neutral way. Please recycle them. Our bottles, child-resistant cap and label are made from polyethylene and are recyclable.

Important note:

Use solvents safely! Always read the label and product information before use.

Keep out of reach of children.

“Glass or HDPE bottle – which is better?”.

Many suppliers use amber glass bottles and advertise that they are much safer and better protect the contents from, for example, UV rays or soluble plastic. However, the fact is that this ingredient is not sensitive to either light or UV, and HDPE (High Density Polyethylene) is a legally approved and suitable storage material. Every industrial manufacturer of DMSO produces, bottles and stores it in HDPE cans, drums or containers.

How can quality be improved by pouring into glass bottles?

Conclusion: HDPE is a legal plastic for storing DMSO and does not mix with the filler in any way. Precise drip filling is much easier with our unbreakable HDPE bottle.

That’s why we only use approved HDPE and not glass – for your safety!

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