About all

Does dmso work. DMSO: Uses, Effectiveness, and Potential Risks Explored

by alexxlab

What is DMSO and how does it work. Is DMSO effective for treating various conditions. What are the potential side effects and precautions of using DMSO. How is DMSO dosed and administered. What do scientific studies say about DMSO’s effectiveness.

Understanding DMSO: Origins and Basic Properties

Dimethyl sulfoxide (DMSO) is a versatile chemical compound with a fascinating history and a wide range of applications. Originally a byproduct of paper manufacturing, DMSO is derived from lignin, a substance found in wood. Its use as an industrial solvent dates back to the mid-19th century, but it wasn’t until the mid-20th century that researchers began exploring its potential medical applications.

DMSO possesses several unique properties that make it interesting for medical use:

  • High permeability: DMSO can easily penetrate the skin and cell membranes
  • Solvent properties: It can dissolve many organic and inorganic substances
  • Potential anti-inflammatory effects
  • Ability to enhance the absorption of other medications

These characteristics have led to DMSO being studied for various medical applications, although its effectiveness for many conditions remains controversial.

FDA-Approved Uses of DMSO in Medicine

While DMSO is often touted for numerous health benefits, it’s important to note that the U.S. Food and Drug Administration (FDA) has only approved its use for a specific medical condition. What is the FDA-approved use of DMSO? The FDA has sanctioned DMSO as a prescription medication for treating symptoms of painful bladder syndrome, also known as interstitial cystitis.

In this application, DMSO is used to wash the bladder, which has been shown to improve symptoms such as pain associated with interstitial cystitis. This approval lends credibility to DMSO’s potential as a therapeutic agent, but it’s crucial to understand that this doesn’t extend to its other purported uses.

Other Medically Supervised Uses

Beyond its FDA-approved use, DMSO is sometimes employed under medical supervision for other conditions. These include:

  • Treatment of shingles
  • Management of complex regional pain syndrome
  • Addressing extravasation (leakage of intravenous drugs from the vein into surrounding tissue)

It’s important to emphasize that these uses, while sometimes practiced by medical professionals, are not FDA-approved and may be considered off-label or experimental.

Exploring DMSO’s Potential in Pain Management

One of the most common reasons people turn to DMSO is for pain relief, particularly in cases of osteoarthritis and other musculoskeletal conditions. But does DMSO actually work for pain management? The evidence is mixed and largely inconclusive.

Some studies have suggested that DMSO may help alleviate pain associated with conditions like osteoarthritis when applied topically. However, a recent analysis of studies on DMSO’s efficacy in treating osteoarthritis pain found that it was not significantly more effective than a placebo in relieving joint pain.

Despite this, some individuals report subjective improvements in pain levels when using DMSO. It’s possible that DMSO’s potential anti-inflammatory properties or its ability to enhance the absorption of other pain-relieving compounds could contribute to these reported benefits.

DMSO for Complex Regional Pain Syndrome

One area where DMSO has shown some promise is in the treatment of complex regional pain syndrome (CRPS), a chronic pain condition that typically affects limbs after an injury. How effective is DMSO for CRPS? Some studies have indicated that applying DMSO cream to the skin may improve pain in people with this condition. However, more research is needed to fully establish its efficacy and safety for this use.

DMSO as an Alternative Cancer Treatment: Separating Fact from Fiction

DMSO has been promoted by some as an “alternative” cancer treatment. However, it’s crucial to approach such claims with skepticism and caution. Do reputable cancer organizations support the use of DMSO for cancer treatment? The American Cancer Society explicitly states that there is no evidence to support the use of DMSO to treat cancer.

In fact, relying on DMSO as a cancer treatment could lead to dangerous delays in receiving proper and effective treatment. Cancer is a complex group of diseases that require evidence-based, specialized medical care. While it’s understandable that individuals facing a cancer diagnosis might explore all possible options, it’s essential to rely on treatments that have been proven safe and effective through rigorous scientific study.

If you or someone you know is considering using DMSO for cancer treatment, it’s crucial to consult with a qualified oncologist to discuss evidence-based treatment options and potential risks associated with unproven therapies.

Potential Side Effects and Risks of DMSO Use

While DMSO is sometimes perceived as a “natural” remedy, it’s important to understand that it can cause a range of side effects, some of which can be serious. What are the most common side effects of topical DMSO use?

  • Skin irritation
  • A strong garlic-like odor
  • Stomach upset

More serious side effects can include:

  • Severe allergic reactions
  • Headaches
  • Itching and burning at the application site

When taken orally, DMSO can cause additional side effects such as:

  • Dizziness
  • Drowsiness
  • Nausea and vomiting
  • Diarrhea or constipation
  • Decreased appetite

It’s worth noting that DMSO can be deadly when used in high concentrations, underscoring the importance of proper dosing and medical supervision.

DMSO and Drug Interactions

One of the most significant risks associated with DMSO use is its potential to interact with other medications. How does DMSO affect other drugs? DMSO can increase the effect of certain medicines, which can lead to serious health issues. Some examples of medications that may interact with DMSO include:

  • Blood thinners
  • Steroids
  • Sedatives

Given these potential interactions, it’s crucial to consult with a healthcare provider before using DMSO, especially if you’re taking other medications.

DMSO Dosage and Administration: Navigating the Uncertainties

One of the challenges in using DMSO is the lack of standardized dosing guidelines for many of its purported uses. Are there established dosing guidelines for DMSO? For its FDA-approved use in treating interstitial cystitis, there are specific protocols followed by healthcare providers. However, for other uses, dosing can be highly variable and potentially risky.

For topical application, such as in attempts to treat osteoarthritis, DMSO gels typically have a concentration of around 25% and are applied three to four times daily. However, DMSO products sold without a prescription can range from 10% to 90% concentration, introducing significant variability and potential for misuse.

The Importance of Product Quality

Another critical factor to consider is the quality of DMSO products. Some DMSO available on the market may be industrial grade, which can contain impurities that are easily absorbed through the skin, potentially leading to serious health effects. This underscores the importance of only using pharmaceutical-grade DMSO under medical supervision.

Special Precautions and Contraindications for DMSO Use

Certain groups of people should exercise extra caution or avoid DMSO altogether. Who should not use DMSO? Pregnant women and those who are breastfeeding should avoid DMSO, as its effects on fetal development and infants are not well understood.

Additionally, individuals with certain health conditions should consult their healthcare provider before using DMSO. These conditions include:

  • Diabetes
  • Asthma
  • Liver conditions
  • Kidney conditions

It’s also crucial to practice proper hygiene when using DMSO topically. Why is hand washing important before applying DMSO? DMSO’s ability to enhance absorption means it can cause anything on the skin to be absorbed more readily. This includes potential contaminants or harmful substances, making thorough hand and skin washing before application essential.

The Regulatory Landscape: DMSO as a Supplement

While DMSO is available as a prescription medication for specific uses, it’s also sold as a dietary supplement in various forms, including gels, creams, and sometimes oral preparations. How is DMSO regulated as a supplement? It’s crucial to understand that dietary supplements are not regulated by the FDA in the same way as prescription drugs.

This means that manufacturers of DMSO supplements are not required to prove their products’ safety or efficacy before selling them. The lack of stringent regulation introduces several potential issues:

  • Variability in product quality and purity
  • Inconsistent concentrations of DMSO in different products
  • Potential for contamination or adulteration
  • Lack of standardized dosing information

Given these factors, individuals considering using DMSO as a supplement should approach with caution and ideally consult with a healthcare provider before use.

Distinguishing DMSO from Other Supplements

It’s important not to confuse DMSO with other supplements that may have similar-sounding names. For instance, Methylsulfonylmethane (MSM) is a different compound often used as a dietary supplement, particularly for joint health. While both contain sulfur, DMSO and MSM have distinct properties and potential effects.

Current Research and Future Perspectives on DMSO

Despite its long history and widespread use, many aspects of DMSO’s effects on human health remain poorly understood. What areas of DMSO research are currently active? Ongoing studies are exploring DMSO’s potential in various applications, including:

  • Enhancing drug delivery systems
  • Treating inflammatory conditions
  • Potential neuroprotective effects
  • Use in cryopreservation of biological materials

While some of these areas show promise, it’s important to approach emerging research with cautious optimism. Many potential applications of DMSO require further study to establish safety and efficacy.

The Need for More Rigorous Studies

One of the challenges in evaluating DMSO’s effectiveness for many conditions is the lack of large-scale, well-designed clinical trials. Many existing studies are small, lack proper controls, or have other methodological limitations. This highlights the need for more robust research to fully understand DMSO’s potential benefits and risks.

As research continues, it’s possible that new applications for DMSO may be discovered and validated. However, until such evidence is available, it’s crucial to rely on established medical treatments and to use DMSO only under appropriate medical supervision for its approved uses.

DMSO: Uses and Risks

Written by Joseph Saling

  • Why Do People Use DMSO?
  • What Are the Risks of Using DMSO?

DMSO, or dimethyl sulfoxide, is a by-product of paper making. It comes from a substance found in wood.

DMSO has been used as an industrial solvent since the mid-1800s. From about the mid-20th century, researchers have explored its use as an anti-inflammatory agent.

The FDA has approved DMSO as a prescription medication for treating symptoms of painful bladder syndrome. It’s also used under medical supervision to treat several other conditions, including shingles.

DMSO is easily absorbed by the skin. It’s sometimes used to increase the body’s absorption of other medications.

DMSO is available without a prescription most often in gel or cream form. It can be purchased in health food stores, by mail order, and on the Internet.

While it can sometimes be found as an oral supplement, its safety is unclear. DMSO is primarily used by applying it to the skin.

DMSO has been used to try to relieve the pain of osteoarthritis. It has also been promoted as an “alternative” cancer treatment.

People have used it to try to treat wounds, burns, and other injuries. People have also used it to try to treat such conditions as:

  • Headache
  • Rheumatoid arthritis
  • Eye problems
  • Scars
  • Scleroderma (disease that causes scar tissue to form in the skin)

Other than its use as a prescription medicine, there is little or no scientific evidence to support other claims made about DMSO’s effectiveness.

The American Cancer Society says there is no evidence to support the use of DMSO to treat cancer. Using it that way could cause serious delays in getting proper and effective treatment.

A recent analysis of studies on the use of DMSO to relieve osteoarthritis pain found that it was not significantly more effective than placebo in relieving joint pain.

There are no studies that provide guidelines for determining the proper dose of DMSO. The gel used to treat osteoarthritis typically has a concentration of 25%. It is applied three or four times a day. But DMSO sold without a prescription can range from 10% concentration to 90%.

Some DMSO on the market may actually be industrial grade. Industrial grade DMSO may contain a number of impurities that can easily be absorbed into the skin with potentially serious health effects.

The most frequent side effects from using DMSO on the skin include:

  • Stomach upset
  • Skin irritation
  • Strong odor of garlic

More serious side effects include:

  • Severe allergic reactions
  • Headaches
  • Itching and burning when applied to the skin

DMSO can also cause a deadly reaction when used in high concentrations.

Using DMSO by mouth can cause:

  • Dizziness
  • Drowsiness
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Decreased appetite

DMSO can increase the effect of some medicines, which can lead to serious health issues. Examples of such medicines include:

  • Blood thinners
  • Steroids
  • Sedatives

The biggest concern of DMSO as a solvent is that when it gets on the skin it will cause anything on the skin to be absorbed. So be sure to wash your hands and skin well before using.

Pregnant women and women who are breastfeeding should not use DMSO, since little is known about its possible effects on the fetus or infant.

You should also not use DMSO without talking to your doctor if you have:

  • Diabetes
  • Asthma
  • Liver and kidney conditions

Always keep in mind that supplements are not regulated by the FDA the same was as drugs are. The manufacturer does not have to prove that a supplement is safe or effective before selling.

Top Picks

Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Dimethylsulfoxide (DMSO) is a chemical that dissolves many organic and inorganic substances. It’s available as a prescription drug and dietary supplement.

DMSO helps medicines get through the skin and can affect proteins, carbohydrates, fats, and water in the body.

People use DMSO for bladderinflammation (interstitial cystitis), limb pain that usually occurs after an injury, and leakage of an IV drug from the vein into surrounding skin and tissue. It is also used for osteoarthritis, bed sores, stomach ulcers, and many other conditions, but there is no good scientific evidence to support most of these other uses.

Don’t confuse DMSO with Methylsulfonylmethane (MSM). These are not the same.

Uses & Effectiveness ?

Effective for

  • Painful bladder syndrome (interstitial cystitis). DMSO is an FDA-approved product for the treatment of this condition. Washing the bladder with DMSO improves some symptoms, such as pain.

Possibly Effective for

  • Limb pain that usually occurs after an injury (complex regional pain syndrome). Applying DMSO cream to the skin seems to improve pain in people with this condition.
  • Leakage of intravenous (IV) drug from the vein into surrounding skin and tissue (extravasation). Some chemotherapy drugs can cause skin and tissue damage if they leak from the vein. Applying DMSO to the skin might prevent further damage if this happens.

Possibly Ineffective for

  • Hardening of skin and connective tissue (scleroderma). Applying DMSO to the skin doesn’t help treat symptoms of scleroderma.

There is interest in using DMSO for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: There isn’t enough reliable information to know if DMSO is safe or what the side effects might be.

When applied to the skin: Non-prescription DMSO is possibly unsafe. Some non-prescription DMSO products might be industrial grade. These aren’t intended for human use and can contain impurities that can cause health issues. DMSO is easily absorbed through the skin, so it can carry these impurities into the body. Side effects might include blistering and burning.

When applied inside the bladder: Prescription DMSO is likely safe. Don’t use DMSO products that are not prescribed by a healthcare professional.

Special Precautions and Warnings

When taken by mouth: There isn’t enough reliable information to know if DMSO is safe or what the side effects might be.

When applied to the skin: Non-prescription DMSO is possibly unsafe. Some non-prescription DMSO products might be industrial grade. These aren’t intended for human use and can contain impurities that can cause health issues. DMSO is easily absorbed through the skin, so it can carry these impurities into the body. Side effects might include blistering and burning.

When applied inside the bladder: Prescription DMSO is likely safe. Don’t use DMSO products that are not prescribed by a healthcare professional.

Pregnancy and breast-feeding: There isn’t enough reliable information to know if DMSO is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Certain blood disorders. Injecting DMSO by IV might cause red blood cells to break down. This might be a problem for people with certain blood disorders. DMSO might make these conditions worse.

Kidney problems: DMSO might harm the kidneys. Check with a healthcare provider before using DMSO if you have kidney problems.

Liver problems: DMSO might harm the liver. Check with a healthcare provider before using DMSO if you have liver problems.br/>

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • DMSO can sometimes increase how much medicine the body absorbs. Applying DMSO to the skin, eyes, or ears at the same time as applying medication can increase how much medicine the body absorbs. This might increase the effects and side effects of the medicine.

  • DMSO might slow blood clotting. Taking DMSO along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

  • Using DMSO with sulindac might reduce how well sulindac works to treat pain. There is also a concern that using DMSO with sulindac can increase the risk for nerve pain.

  • DMSO can increase a chemical in the body called acetylcholine. Some medications that are used for glaucoma, Alzheimer disease, and other conditions, also increase acetylcholine levels. Taking DMSO with these medications might increase the chance of side effects.

  • Using DMSO with verteporfin might reduce how well verteporfin works.

  • Using DMSO to dissolve platinum agents onto the skin might reduce how well these drugs work to treat cancer. Examples of platinum agents include carboplatin, cisplatin, and oxaliplatin.

Dosing

DMSO has most often been applied to the skin by adults in various forms, including creams, gels, and solutions. It is also applied inside the bladder. DMSO is available as a prescription and in dietary supplements. Speak with a healthcare provider before use.

View References

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

Scientists have found a way to destroy the toxic “eternal chemicals” that flooded the world – Gazeta.Ru

Scientists have found a way to destroy the toxic “eternal chemicals” that flooded the world – Gazeta.Ru | News

close

100%

Researchers have shown that a mixture of soap and DMSO solvent can break down per- and polyfluoroalkyl compounds (PFAS), known as “timeless chemicals”. Development reported Science .

Two years ago, researchers from the US Environmental Protection Agency placed a sample of PFAS in a common solvent (DMSO) to study toxicity, but the substance began to degrade. The new study builds on this observation. Scientists from Northwestern University studied various mixtures containing DMSO. The mixture of DMSO and sodium hydroxide, a common soap ingredient, showed the greatest effectiveness when heated to boiling point.

This method works with approximately 40% PFAS. Now it has to be tested on large volumes. Those compounds, the destruction of which chemists have studied, are used in fire-fighting foams and the production of non-stick coatings.

PFAS are known as “timeless chemicals” because they can remain in the environment for decades. Recently, they have even been found in rainwater in the Tibetan Plateau in quantities far exceeding safe ones. The new method will cheaply and safely cleanse the planet of potentially toxic and carcinogenic substances.

Subscribe to Gazeta.Ru in News, Zen and Telegram.
To report a bug, highlight the text and press Ctrl+Enter

News

Zen

Telegram

Artur Muradyan

Is it worth vacationing in Turkey and Egypt in the summer of 2023?

About holidays in popular foreign destinations

Alexander Tikhomirov

How to teach a child financial literacy

Alexander Tikhomirov, Executive Director of SberLife Insurance, on correct pocket spending

Georgy Bovt

Why does Russia need a “grain deal”

Who is pouring water on whose mill in the food exports of the Black Sea region

Alena Solntseva

The Librarian TV Series: Lord of the Battle Reading Rooms

About the new show with Nikita Efremov

Aram Ter-Ghazaryan

How Internet Cherkizon was destroyed in the “quarrel in the sandbox”

What threatens marketplaces with the new law on online trading

DMSO (dimethyl sulfoxide) in the best quality pharmaceutical premium

DMSO – Universal Solvent (100 ml)

Dimethyl Sulfoxide (DMSO) is a colorless and odorless organic universal solvent used in laboratory and technical applications. Very high purity of 99.9% meets Ph.Eur certification. Depending on the application, it is easily mixed with water in any ratio. It has an amazing amount of good properties and is extremely versatile.

Benefits of using DMSO:

  • Pharmaceutical purity according to the European Pharmacopoeia

  • Integrated dropper for easy dosing

  • TÜV Rheinland tested: 100% EU-compliant

  • Filled in break-proof and child-proof HDPE bottle

  • is perfect for travel, outdoor or crisis preparedness!

  • The original, only from AQUARIUS pro life

Disadvantages compared to other DMSO solutions:

  • often no pharmaceutical safety

  • No TÜV-tested EU conformity

  • Often bottled in fragile glass bottles

  • is therefore impractical for travel and outdoor use.

Benefits of using DMSO:

  • Pharmaceutical purity according to the European Pharmacopoeia

  • Integrated dropper for easy dosing

  • TÜV Rheinland tested: 100% EU-compliant

  • Filled in break-proof and child-proof HDPE bottle

  • is perfect for travel, outdoor or crisis preparedness!

  • The original, only from AQUARIUS pro life

Disadvantages compared to other DMSO solutions:

  • often no pharmaceutical safety

  • No TÜV-tested EU conformity

  • Often bottled in fragile glass bottles

  • is therefore impractical for travel and outdoor use.

Content:

100ml 99.9% DMSO ultrapure Ph.Eur in HDPE bottle

(CAS no: 67-68-5, EC no: 200-664-3) Taric: 29091990

Storage and shelf life:

Store in a dry place at room temperature, well closed and out of the reach of children!

DMSO becomes crystalline and solid at low temperatures below 18°C, eg during transport or in winter. This is completely normal and harmless. When heated in a warm water bath, it becomes liquid again. Remove residues on fabrics and surfaces immediately with a damp cloth. DMSO is a long-term stable compound and therefore has a very long shelf life.

Areas of use:

Depending on the application, DMSO can be easily mixed with water in any ratio. Dimethyl sulfoxide has an amazing amount of good properties and is extremely versatile, being used in cosmetics, pharmaceuticals, and as a widely used solvent in laboratories and engineering, among others.

Environment protection:

The raw materials for our sustainable packaging and product information sheet come from sustainable forestry (FSC) and are printed in a climate-neutral way. Please recycle them. Our bottles, child-resistant cap and label are made from polyethylene and are recyclable.

Important note:

Use solvents safely! Always read the label and product information before use.

Keep out of reach of children.

“Glass or HDPE bottle – which is better?”.

Many suppliers use amber glass bottles and advertise that they are much safer and better protect the contents from, for example, UV rays or soluble plastic. However, the fact is that this ingredient is not sensitive to either light or UV, and HDPE (High Density Polyethylene) is a legally approved and suitable storage material. Every industrial manufacturer of DMSO produces, bottles and stores it in HDPE cans, drums or containers.

How can quality be improved by pouring into glass bottles?

Conclusion: HDPE is a legal plastic for storing DMSO and does not mix with the filler in any way. Precise drip filling is much easier with our unbreakable HDPE bottle.

That’s why we only use approved HDPE and not glass – for your safety!

Other customers also bought: