Does Klonopin cause weight gain. How does Klonopin affect metabolism. What are the long-term effects of Klonopin use. Can Klonopin lead to addiction. How long does Klonopin stay in your system. What are the alternatives to Klonopin for anxiety and panic disorders. How to safely discontinue Klonopin use.

The Relationship Between Klonopin and Weight Changes

Klonopin, also known by its generic name clonazepam, is a medication that belongs to the benzodiazepine family. While primarily prescribed for treating anxiety disorders, panic attacks, and certain types of seizures, many users have reported weight changes as a side effect. But does Klonopin directly cause weight gain?

The connection between Klonopin and weight gain is not straightforward. While some individuals may experience weight gain, others might not notice any significant changes. The potential for weight gain is often attributed to indirect effects of the medication rather than a direct metabolic impact.

Factors Contributing to Weight Gain on Klonopin

• Slowed metabolism: Klonopin may slow down the body’s metabolic processes, affecting how it converts food into energy.
• Increased appetite: Some users report an increase in hunger or cravings while taking the medication.
• Reduced physical activity: Klonopin can cause drowsiness and fatigue, potentially leading to a more sedentary lifestyle.
• Fluid retention: In some cases, Klonopin may cause the body to retain more water, resulting in temporary weight gain.

It’s important to note that weight changes can vary significantly from person to person. Some individuals may experience weight loss due to reduced anxiety-related eating, while others might maintain their current weight.

Understanding Klonopin’s Mechanism of Action

To better comprehend the potential side effects of Klonopin, including weight changes, it’s crucial to understand how the medication works in the body. Klonopin acts on the central nervous system by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that helps reduce brain activity.

How Klonopin Affects the Brain and Body

1. Binding to GABA receptors: Klonopin increases the efficiency of GABA, leading to a calming effect on the brain.
2. Reducing neurotransmitter activity: This action helps alleviate symptoms of anxiety and prevent seizures.
3. Muscle relaxation: Klonopin can cause relaxation of muscles throughout the body.
4. Sedation: Many users experience drowsiness or fatigue as a result of the medication’s effects.

These effects on the brain and body can indirectly influence weight by altering energy levels, appetite, and metabolism. However, the extent of these changes varies among individuals.

Managing Weight While Taking Klonopin

For those concerned about potential weight gain while taking Klonopin, there are several strategies that can help maintain a healthy weight:

• Regular exercise: Engaging in physical activity can help counteract the sedative effects of Klonopin and boost metabolism.
• Balanced diet: Focusing on nutrient-dense foods and portion control can help manage weight effectively.
• Hydration: Drinking plenty of water can help reduce fluid retention and support overall health.
• Sleep hygiene: Establishing a consistent sleep schedule can help regulate metabolism and energy levels.
• Regular check-ups: Monitoring weight and discussing concerns with a healthcare provider is essential.

It’s crucial to consult with a healthcare professional before making any significant changes to diet or exercise routines while taking Klonopin.

Klonopin Side Effects Beyond Weight Changes

While weight changes are a concern for some users, Klonopin can cause various other side effects that individuals should be aware of. Understanding these potential effects can help users make informed decisions about their treatment and recognize when to seek medical attention.

Common Side Effects of Klonopin

• Drowsiness and fatigue
• Dizziness
• Impaired coordination
• Memory problems
• Mood changes
• Nausea
• Blurred vision

Most of these side effects are mild and tend to diminish as the body adjusts to the medication. However, if they persist or worsen, it’s important to consult a healthcare provider.

Serious Side Effects Requiring Immediate Attention

1. Severe allergic reactions
2. Suicidal thoughts
3. Severe dizziness or fainting
4. Unusual mood changes or behavior
5. Difficulty breathing
6. Seizures (in individuals without a history of seizures)

These serious side effects are rare but require immediate medical attention if they occur. It’s crucial for Klonopin users to be aware of these potential risks and to seek help promptly if they experience any concerning symptoms.

Long-Term Effects of Klonopin Use

While Klonopin can be an effective treatment for anxiety disorders and seizures, long-term use of the medication can lead to various health concerns. Understanding these potential long-term effects is crucial for individuals considering or currently using Klonopin as part of their treatment plan.

Potential Long-Term Consequences

• Physical dependence: Regular use of Klonopin can lead to physical dependence, making it difficult to stop taking the medication without experiencing withdrawal symptoms.
• Cognitive impairment: Some studies suggest that long-term use of benzodiazepines like Klonopin may be associated with cognitive decline, particularly in older adults.
• Increased risk of falls: Especially in elderly patients, long-term use of Klonopin can increase the risk of falls and fractures due to its sedative effects.
• Tolerance: Over time, some individuals may develop a tolerance to Klonopin, requiring higher doses to achieve the same therapeutic effect.
• Mood changes: Long-term use may contribute to depression or worsen existing mood disorders in some individuals.

It’s important to note that not all individuals will experience these long-term effects, and the benefits of treatment may outweigh the risks for many patients. Regular follow-ups with a healthcare provider can help monitor for potential long-term effects and adjust treatment as necessary.

Alternatives to Klonopin for Anxiety and Panic Disorders

While Klonopin can be effective for managing anxiety and panic disorders, it’s not the only option available. For individuals concerned about potential side effects or seeking alternatives, there are several other treatment approaches to consider.

Medication Alternatives

1. Selective Serotonin Reuptake Inhibitors (SSRIs): These antidepressants are often used as a first-line treatment for anxiety disorders.
2. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Another class of antidepressants that can be effective for anxiety.
3. Buspirone: An anti-anxiety medication that works differently from benzodiazepines and has a lower risk of dependence.
4. Beta-blockers: These medications can help manage physical symptoms of anxiety, such as rapid heartbeat.

Non-Medication Approaches

• Cognitive Behavioral Therapy (CBT): A type of psychotherapy that helps individuals identify and change negative thought patterns and behaviors.
• Mindfulness and meditation: Practices that can help reduce anxiety and promote relaxation.
• Exercise: Regular physical activity has been shown to have anxiety-reducing effects.
• Lifestyle changes: Improving sleep habits, reducing caffeine intake, and managing stress through various techniques can help alleviate anxiety symptoms.

It’s essential to work closely with a healthcare provider to determine the most appropriate treatment approach based on individual needs and circumstances.

Safely Discontinuing Klonopin Use

For individuals who have been using Klonopin and wish to stop, it’s crucial to approach discontinuation carefully and under medical supervision. Abruptly stopping Klonopin can lead to withdrawal symptoms and potentially dangerous health effects.

Steps for Safe Discontinuation

1. Consult with a healthcare provider: Discuss the reasons for wanting to stop Klonopin and develop a personalized tapering plan.
2. Gradual tapering: Slowly reducing the dosage over time helps minimize withdrawal symptoms and allows the body to adjust.
3. Monitor for withdrawal symptoms: Be aware of potential symptoms such as anxiety, tremors, sleep disturbances, and mood changes.
4. Consider supportive therapies: Engage in psychotherapy or support groups to help manage anxiety during the discontinuation process.
5. Explore alternative treatments: Work with a healthcare provider to identify other treatment options for managing underlying conditions.

The tapering process can take weeks or even months, depending on the individual’s dosage and duration of use. Patience and close medical supervision are essential for a safe and successful discontinuation.

Klonopin Detection and Drug Testing

Understanding how long Klonopin remains detectable in the body is important for various reasons, including drug testing and assessing potential interactions with other medications. The detection time can vary based on several factors.

Factors Affecting Detection Time

• Dosage and frequency of use
• Individual metabolism
• Age and overall health
• Body mass and composition
• Hydration levels
• Type of drug test used

According to studies, including one from the Mayo Clinic, benzodiazepines like Klonopin can be detectable in urine for up to 30 days. However, this timeframe can vary significantly from person to person.

Detection Windows for Different Test Types

1. Urine tests: Can detect Klonopin for 3-30 days after last use
2. Blood tests: Usually detectable for 1-2 days
3. Saliva tests: May detect the drug for 1-5 days
4. Hair follicle tests: Can potentially detect Klonopin use for several months

It’s important to note that some common drug tests may not specifically screen for Klonopin, and false negatives are possible. For accurate results, specialized tests may be required.

Understanding the potential for weight changes and other side effects associated with Klonopin use is crucial for individuals considering or currently using this medication. While weight gain is a possible side effect, it’s not universal, and many factors contribute to individual responses. By working closely with healthcare providers, maintaining a healthy lifestyle, and being aware of potential risks and alternatives, individuals can make informed decisions about their treatment and manage any side effects effectively. Remember, any changes to medication regimens should always be made under the guidance of a qualified healthcare professional.

Side Effects, Dosage, Precautions, Uses

1. Is clonazepam a sleeping pill?

Clonazepam is prescribed for treating panic and anxiety disorders and seizures. However, it is also effective in the treatment of difficult REM sleep behavior disorder (RBD). It lessens the symptoms in nearly 90% of patients. It has also shown minimal evidence of tolerance or abuse. The patient generally starts responding within the first week.

2. What not to take with clonazepam?

Clonazepam may potentially interact with other medications to increase drowsiness and reduce the effectiveness of the medicine. Strictly avoid taking it with other benzodiazepine medications, like:

• Opioid cough medicines like codeine cough syrup
• Sleeping medicine like zolpidem (Ambien®)
• Other drugs which treat anxiety, psychotic disorders, bipolar personality disorder, epileptic seizures, and depression (such as amitriptyline)

3. Does clonazepam cause depression?

People who abuse their medicine intake and consume larger doses for a long duration can experience various mental health issues like intense mood swings and hallucinations, and the risk of depression. Moreover, it can also trigger suicidal thoughts. Thus, it is crucial to monitor mood fluctuations. Occasionally, paradoxical reactions like increased excitement and talkativeness may also occur.

4. How much clonazepam should I take?

The quantity intake varies for each individual depending on their situation. For panic or anxiety disorders, the recommended dose for adults is 0.25 mg twice per day. If necessary, the doctor can increase the intake in increments of 0.125 mg to 0.25 mg every 3 days, until the disorder is controlled or lessened. The maximum dosage, however, should not exceed 4 mg each day.

5. Can clonazepam overdose cause death?

Excess intake of clonazepam is harmful to health. The side effects include sweating, confusion, extreme drowsiness or sedation, and weakened body coordination. Overdosing on or combining clonazepam with other unsuitable depressants can cause one to stop breathing and experience substance blackout. This may result in death. Hence, do not exceed the prescribed intake of the tablet.

6. Is clonazepam a benzodiazepine?

Yes, clonazepam (Klonopin) belongs to the family of drugs called benzodiazepines. Clonazepam is an anticonvulsant and antiepileptic medication. Doctors prescribe these drugs to both adults and children for treating disorders like panic, anxiety, and seizures. This drug directly affects the central nervous system to get the desired outcome.

7. When to take clonazepam?

Clonazepam can be consumed with or without food. In case of an upset stomach, take it with meals. Depending on the individual situation, the specialist will prescribe the necessary dosage you must consume, either regularly or on an as-needed basis. Typically, the doctors restrict the amount one can consume daily to avoid side effects.

8. Can you snort clonazepam?

Clonazepam is prescribed either as a tablet or as an orally disintegrating form. Doctors warn against snorting (insufflation) the drug. Drug abusers tend to abuse this substance for pleasure and relaxation by snorting it. However, that can cause a faster onset of feeling ‘high’ and other side effects, than when the drug is taken in an oral form.

9. Does clonazepam cause weight gain?

As clonazepam is a benzodiazepine, it is often associated with weight gain, especially for people addicted to the substance. This is because: Clonazepam may slow your metabolism, i.e. how the body converts food into energy It can make you feel lethargic. This leads to reduced physical activities and binging of junk food, thus, causing weight gain.

10. How long can clonazepam be detected in urine?

According to a Mayo Clinic study, benzodiazepines like clonazepam can stay in the system or urine for up to 30 days. It depends on your age, metabolic process, dosage, dosage frequency, and sensitivity to the drug. The elimination time varies significantly from person to person. Sometimes, common tests can miss out on detecting clonazepam as well.

Get top-notch healthcare consultation at Yashoda Hospitals. Our team of experts can help you treat your diverse medical needs and answer your prescription-related queries.

What they are and how to manage them

Klonopin (clonazepam) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it to treat certain adults with:

• seizure disorders, including atonic seizures, myoclonic seizures and some absence seizures
• panic disorder with or without agoraphobia

In addition, the FDA has also approved Klonopin to treat seizure disorders in children of all ages.

Here are some fast facts about Klonopin:

• Active ingredient: clonazepam
• Drug class: benzodiazepine
• Drug form: oral tablet

Depending on your condition and treatment plan, doctors may recommend taking Klonopin short term or long term. For example, it may be beneficial to take Klonipin long term to treat a seizure disorder.

However, if you’re taking Klonopin for panic disorder, your doctor may recommend taking the drug short term. It’s unknown if Klonopin is effective at treating this condition long term. So, before you start taking Klonopin, talk with your doctor about the best treatment plan for you.

As with other drugs, Klonopin can cause side effects. Read on to learn about potential common, mild, and serious side effects. For a general overview of Klonopin, including details about its uses, see this article.

Klonopin can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

These are just a few of the more common side effects reported by people who took Klonopin in clinical trials:

• increased saliva
• drowsiness
• muscle pain or weakness
• dizziness
• headache

* For more information about this side effect, see “Side effect specifics” below.

Mild side effects can occur with Klonopin use. This list does not include all possible mild side effects of the drug. For more information, you can refer to Klonopin’s prescribing information.

Mild side effects that people taking Klonipin have reported include:

• increased saliva
• muscle pain or weakness
• dizziness
• low blood pressure
• headache
• dry mouth
• fatigue
• constipation
• weight changes
• sleepiness*
• sexual side effects, such as changes in libido (sex drive)*
• nausea*
• mild allergic reaction*

These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you develop a side effect while taking Klonopin and want to tell the FDA about it, visit MedWatch.

* For more information about this side effect, see “Side effect specifics” below.

Klonopin may cause serious side effects. Though serious side effects aren’t common, they can occur. The list below may not include all possible serious side effects of the drug. For more information, you can refer to Klonopin’s prescribing information.

If you develop serious side effects while taking Klonopin, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Serious side effects that have been reported and their symptoms include:

• Seizures. Symptoms can include:
  • confusion
  • loss of consciousness
  • uncontrolled movement of the arms or legs
• Anger, depression, or other mood changes. Symptoms can include:
  • feeling hopeless
  • irritability
  • difficulty falling asleep or staying asleep
• Difficulty breathing (respiratory depression). Symptoms can include:
  • slow, shallow breaths
  • sleepiness
  • shortness of breath
• Low blood pressure. Symptoms can include:
  • dizziness
  • blurry vision
  • confusion
• Suicidal thoughts or behaviors. Symptoms can include:
  • thoughts of suicide
  • new or worsening depression
  • impulsiveness
• Impaired thinking or memory loss.
• Problems with motor skills, such as walking.
• Risk of physical withdrawal and dependence.*
• Risk of serious injury or death if taken with opioids.*
• Risk of misuse or addiction.†
• Severe allergic reaction.

* Klonopin has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effect specifics” section below.
† Klonopin has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Klonopin and Misuse” section below.

Suicide prevention

If you know someone at immediate risk of self-harm, suicide, or hurting another person:

• Ask the tough question: “Are you considering suicide?”
• Listen to the person without judgment.
• Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
• Stay with the person until professional help arrives.
• Try to remove any weapons, medications, or other potentially harmful objects.

If you or someone you know is having thoughts of suicide, a prevention hotline can help. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988.

Click here for more links and local resources.

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Klonopin is only approved to treat children with certain seizure disorders. This medication is not currently approved to treat children with panic disorder.

Typically, side effects that children experience are similar to those in adults. However, children can be at a higher risk of paradoxical reactions. Paradoxical reactions occur when someone has the opposite reaction than what is expected.

So, for example, sleepiness is one of the common side effects of Klonopin. However, if a child has a paradoxical reaction, they may become more energetic after taking Klonopin.

If you’re concerned about side effects that your child may experience from taking Klonopin, talk with their doctor.

Klonopin may cause several side effects. Here are some frequently asked questions about the drug’s side effects and their answers.

What are the long-term side effects of Klonopin?

Although rare, it’s possible for people taking Klonopin to experience long-term side effects. Examples of long-term side effects that can occur from this medication include:

• seizures
• anger, depression, or other mood changes
• suicidal thoughts or behaviors
• impaired thinking or memory loss
• problems with motor skills, such as walking
• withdrawal and dependence*
• misuse or addiction†

* Klonopin has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effect specifics” section below.
† Klonopin has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Klonopin and Misuse” section below.

If you’re concerned about developing long-term side effects from taking Klonopin, talk with your doctor or pharmacist. They can discuss the risk of long-term side effects occurring and the best ways to treat or help prevent them.

Does Klonopin cause weight gain?

It is possible for Klonopin to cause weight gain. Though this was not a common side effect reported in clinical trials, it can occur. It’s unknown how often weight gain may occur from taking Klonopin.

If you experience weight gain during your treatment with Klonopin, talk with your doctor. They can help determine what may be causing the weight gain. They may also be able to help with ways to manage your weight.

If you have additional questions about Klonopin and weight gain, talk with your doctor or pharmacist.

Is it possible to have overdose symptoms from taking too much Klonopin?

Yes, you can develop overdose symptoms from taking too much Klonopin. In fact, taking too much Klonopin can even be life threatening. Due to these possible risks, Klonopin has a boxed warning for the risk of misuse or addiction, which can lead to overdose symptoms. For more information on this risk, see the “Klonopin and misuse” section below.

It’s important to only take the dose of Klonopin that your doctor prescribes for you. Do not take more medication than your doctor recommends. If you feel that Klonopin is not working for you, talk with your doctor about other treatment options that may be available.

It’s possible for any benzodiazepine, including Klonopin, to increase the risk of misuse or addiction. In fact, Klonopin has a boxed warning for this risk. A boxed warning is the most serious warning recommended by the FDA. The purpose of a boxed warning is to alert patients and prescribers about the risks of taking a medication.

It’s possible that taking Klonopin may increase your risk of misuse or addiction. Sometimes, misusing a drug can lead to serious side effects, including overdose, which can be life threatening. Examples of Klonopin overdose symptoms may include:

• sleepiness
• confusion
• decreased reflexes
• coma

If you develop symptoms of a Klonopin overdose, call 911 or see a doctor right away.

Misusing a medication means using it in a way that’s different than how your doctor prescribed it for you. So, it’s important that you always follow your doctor’s instructions on how to take your medication. Before you start treatment with Klonopin, tell your doctor if you have a history of misusing a medication. In this case, they may monitor you more often for symptoms of misuse or addiction.

In order to prevent the misuse of Klonopin, doctors typically prescribe the lowest possible dose of the drug for the shortest possible time.

If you have questions or concerns about the possibility of misuse or addiction occurring from taking Klonopin, talk with your doctor pharmacist.

Learn more about some of the side effects that Klonopin may cause. To find out how often side effects occurred in clinical trials, see the prescribing information for Klonopin.

Risk of physical withdrawal and dependence

It’s possible for Klonopin to cause physical withdrawal and dependence. Withdrawal and dependence can occur even if you take Klonopin as prescribed by your doctor. Because of this, Klonopin has a boxed warning for the risk of withdrawal or dependence occurring.

Dependence can occur when your body is used to taking a medication, and you need the drug in order to feel normal. Withdrawal can also occur when you stop taking a drug that your body has become dependent on.

Examples of Klonopin withdrawal side effects can include:

• fatigue
• stomach symptoms, such as nausea, vomiting, or diarrhea
• restlessness
• depression
• seizures
• hallucinations

The early stage of withdrawal can occur soon after you stop taking Klonopin. However, you may experience protracted withdrawal, which can last from weeks to even months after stopping Klonopin.

You may be at a higher risk of dependence or withdrawal if you take a higher dose of Klonopin or take the drug for a long time.

What you can do

In order to help prevent withdrawal symptoms, talk with your doctor before stopping treatment with Klonopin. They will likely recommend slowly decreasing your dose of the drug over time. This can reduce your risk of developing withdrawal symptoms. In addition, they may recommend a different treatment option for your condition.

If you have additional questions or concerns about the risk of withdrawal or dependence from taking Klonopin, talk with your doctor or pharmacist.

Risk of serious injury or death if taken with opioids

Taking a benzodiazepine drug, such as Klonopin, with an opioid drug may cause serious injury or be life threatening. Because of this, Klonopin has a boxed warning for the risk of serious injury or death if the drug is combined with an opioid. A boxed warning is the most serious warning that the FDA recommends. The purpose of a boxed warning is to alert patients and prescribers about the risks of taking a medication.

Klonopin and opioid drugs can cause serious side effects, which can be life threatening. Examples of these side effects may include:

• difficulty breathing or respiratory depression
• sleepiness
• coma

So, taking these drugs together can further increase your risk of side effects.

What you can do

Always tell your doctor if you are taking an opioid drug before starting treatment with Klonipin. They may be able to recommend a different medication for you so that you do not combine the two drugs. If that’s not possible, your doctor may recommend taking the lowest possible doses of Klonopin and the opioid drug. They will also likely recommend taking the combination for the shortest time possible.

Before you start taking Klonopin along with an opioid drug, your doctor will discuss the risks with you. If you have additional questions or concerns, talk with your doctor or pharmacist.

Sleepiness

You may experience sleepiness from taking Klonopin. In fact, sleepiness was one of the most common side effects reported in clinical trials of Klonopin.

What you can do

If you notice sleepiness that’s bothersome to you while you are taking Klonopin, talk with your doctor. They may be able to recommend ways to help manage this side effect. For example, they may reduce your dose of Klonopin to see if your sleepiness improves.

Nausea

You may develop nausea from taking Klonopin. Nausea wasn’t a common side effect in clinical trials of Klonopin. In fact, nausea was only reported in people taking Klonopin for seizure disorders. This side effect was not seen in studies of people taking Klonopin for panic disorder.

What you can do

If you develop nausea during your treatment with Klonopin, talk with your doctor. They may be able to help recommend ways to reduce this side effect from occurring. For example, taking a medication with food might help reduce symptoms of nausea.

Sexual side effects

It’s possible to develop sexual side effects during your treatment with Klonopin. Though sexual side effects were not commonly reported in clinical trials of Klonopin, they can occur.

Sexual side effects were seen in people taking Klonopin for either panic disorder or seizure disorders. Examples of sexual side effects may include:

• changes in libido
• delayed orgasm
• erectile dysfunction

What you can do

If you experience sexual side effects from taking Klonopin, talk with your doctor. They may be able to recommend ways to manage these side effects. For example, your doctor may recommend taking Viagra (sildenafil) to treat erectile dysfunction caused by Klonopin.

If you have concerns about sexual side effects from taking Klonopin, talk with your doctor.

Allergic reaction

As with most drugs, Klonopin can cause an allergic reaction in some people. This rarely occurred in clinical trials of Klonopin.

Symptoms can be mild or serious and can include:

• skin rash
• itching
• flushing
• swelling under your skin, typically in your eyelids, lips, hands, or feet
• swelling of your mouth, tongue, or throat, which can make it hard to breathe

What you can do

For mild symptoms of an allergic reaction, call your doctor right away. They may recommend ways to ease your symptoms and determine whether you should keep taking Klonopin. However, if your symptoms are serious and you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Before taking Klonopin, talk with your doctor about any medical conditions that you have. They can help determine whether Klonopin is safe for you to take.

This drug has boxed warnings about risk of misuse or addiction, physical withdrawal and dependence, and serious injury or death if taken with opioids. These are serious warnings from the Food and Drug Administration (FDA). For details, see the “Side effect specifics” section above.

Other precautions

Be sure to talk with your doctor about your health history before you take Klonopin. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. These are considered drug-condition or drug-factor interactions. The conditions and factors to consider include:

Liver problems. Klonopin is broken down in your body by your liver. If your liver is not working well to break the drug down, it can build up in your body. Having too much Klonopin in your body can increase your risk of side effects or even overdose, which can be life threatening. So, if you have liver problems, your doctor may recommend a lower dose of Klonopin or more frequent monitoring while you are taking the drug.

Breathing problems. Tell your doctor if you have any breathing problems, such as chronic obstructive pulmonary disorder (COPD) or asthma. Klonopin can cause difficulty breathing or respiratory depression. If you have a breathing problem, taking this medication may worsen your condition. In this case, your doctor can help to determine whether Klonopin is a safe treatment option for you.

Glaucoma. It’s possible that Klonopin can increase symptoms of glaucoma. Sometimes, it is safe to take Klonopin if you have glaucoma. However, your doctor may recommend a different treatment option if you have glaucoma. Talk with your doctor to determine the best treatment plan for you.

Allergic reaction. If you’ve had an allergic reaction to Klonopin or any of its ingredients, your doctor will likely not prescribe Klonopin. Ask your doctor what other medications may be better options for you.

Kidney problems. Klonopin exits your body through your kidneys. If your kidneys are not working properly, Klonopin can build up in your body. This can increase your risk of side effects, which in some cases, can be severe or life threatening. Due to this risk, your doctor may recommend a lower dose of Klonopin. Sometimes, they may recommend more frequent monitoring or a different treatment option for you.

Older adults. If you are an older adult (age 65 years or older), you may be at an increased risk of side effects from Klonopin. For example, older adults may have a higher risk of sleepiness, dizziness, or memory problems. Because of these risks, doctors may recommend that older adults take the lowest possible dose of Klonopin. They may also recommend more frequent monitoring for side effects of the drug.

Mood problems. Tell your doctor about any mood problems that you have before starting treatment with Klonopin. Rarely, Klonopin can increase your risk of mood problems, including depression or suicidal thoughts. If you have a mood problem, your doctor can help determine whether Klonopin may be safe for you.

Seizure disorders. Rarely, Klonopin can increase your risk of seizures. If you have a seizure disorder, taking Klonopin may make your condition worse. Talk with your doctor if you have a seizure disorder to see whether Klonopin may be a safe treatment option for you.

Porphyria. If you have a genetic condition called porphyria, tell your doctor before taking Klonopin. It’s possible for Klonopin to worsen porphyria symptoms, such as pain in the abdomen, chest, back, or legs. Your doctor can help determine whether Klonopin may be a safe option for you.

Alcohol with Klonopin

You should not drink alcohol while you are taking Klonopin. Drinking alcohol during your treatment with Klonopin can increase your risk of side effects which may be life threatening. These side effects can include:

• dizziness
• sleepiness
• difficulty breathing
• overdose
• coma

Drinking alcohol while taking a benzodiazepine, such as Klonopin, can cause physical dependence and misuse.*

If you have questions about drinking alcohol while taking Klonopin, talk with your doctor.

* Klonopin has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Klonopin and Misuse” section above.

Pregnancy and breastfeeding while taking Klonopin

It’s unknown if it’s safe to take Klonopin during pregnancy or what risks it may cause. It’s also unknown if it’s safe to breastfeed while taking Klonopin.

At this time, it’s not known if Klonopin may cause harm to a developing fetus. However, congenital anomalies (commonly known as birth defects) or developmental problems were reported in animal studies. It’s important to note that animal studies do not always indicate what may happen in humans.

In addition, if you take Klonopin during pregnancy, the baby may be born dependent on Klonopin, which can cause withdrawal symptoms, difficulty breathing, or trouble feeding.

There is a pregnancy registry available for people that take Klonopin during pregnancy. The purpose of a pregnancy registry is to collect information on a drug’s effects during pregnancy. This can help determine how safe a drug may be during pregnancy. To sign up for the registry, call 888-233-2334 or visit the webpage.

Klonopin use is not recommended while breastfeeding. The drug is known to pass into breast milk. However, it’s not known at this time what risks this may cause in children who are breastfed.

If you’re pregnant, planning to become pregnant, or breastfeeding, talk with your doctor to see whether Klonopin is safe for you.

Klonopin may cause side effects to occur. In most cases, side effects from this drug are mild. However, serious side effects of Klonopin are also possible.

If you’d like to learn more about Klonopin, talk with your doctor or pharmacist. They can help answer any questions you have about the drug’s side effects.

Besides talking with your doctor, you can do some research on your own. These articles might help:

• More information about Klonopin. For details about other aspects of Klonopin, refer to this article.
• Drug comparison. To learn how Klonopin compares with Xanax, read this article.
• Dosage. For information about the dosage of Klonopin, view this article.
• Interactions. To find out about Klonopin’s interactions, see this article.
• A look at your condition. For details about panic disorder, visit our mental health hub. And to learn more about seizures, see our epilepsy and seizures hub.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

How hormones make you gain weight – 4fresh blog

Elena and Anastasia Kostyukhin

The authors of the article. Nutritionists, founders of the GetHealth healthy lifestyle project

Have you tried everything but still can’t lose weight? Maybe your hormones are to blame.

Steady accumulation of fat may be the result of hormonal imbalance. In this case, conventional diets and other recommendations no longer work, because they do not address the hormonal underlying causes, such as excess cortisol, low insulin and/or leptin sensitivity, estrogen imbalance, hypothyroidism (insufficiency of hormones produced by the thyroid gland). In fact, some hormonal imbalances can make losing weight completely impossible.

In this article, you will learn why hormonal imbalances can cause you to gain weight and how to deal with it. Let’s figure it out.

And what about hormones?

Hormones are special molecules that act as intermediaries between different parts of your body. When they enter the bloodstream in response to specific stimuli, they are immediately transferred to certain target cells.

Targets for each hormone differ in the presence of specific, suitable receptors. The interaction between the hormone and the receptor sets off a cascade of biochemical reactions in the target cell that ultimately alters the function or activity of the cell.

Thus, hormones regulate complex processes, including growth, energy production, blood sugar, hunger and satiety, and metabolism.

1. Insulin

When it comes to weight loss, one of the most important hormones is insulin. It is produced by the pancreas and is known to regulate blood sugar levels, inhibit lipolysis (the breakdown of fats) and stimulate lipogenesis (the formation of fat stores).

Chronically high insulin levels can lead to insulin resistance. In this state, the cells lose their sensitivity to the hormone, and the pancreas has to produce more and more insulin in order to control blood sugar levels. However, this is getting harder and harder to do.

As a result, there comes a point when the level of sugar and insulin in the blood becomes steadily high. This leads to weight gain and a high risk of type 2 diabetes.

Many factors contribute to the development of insulin resistance. One of these is thought to be elevated levels of free fatty acids in the blood.

The main cause of high free fatty acids is eating too many calories and being overweight. In fact, overeating, weight gain, and obesity are strongly associated with insulin resistance.

Other potential causes of insulin resistance include:

1. Frequent use of fructose as an added sugar (not from fruits).
2. Oxidative stress: a consequence of chronic stress, smoking, drinking alcohol and “artificial” foods, contact with polluted environment, overtraining.
3. Sedentary lifestyle, lack of activity.
4. Gut microbiota: Disruption of the bacterial environment in the gut can cause inflammation, which exacerbates insulin resistance and other metabolic problems.

What can you do?

• When you eat a lot of sugar, fast food and processed carbohydrates (cakes, pastries), insulin goes out of whack. That is why the very first reasonable step is to minimize these foods in your diet.

• Eat a whole food diet. Be sure to include healthy fats: nuts, oily fish. If there are no contraindications, try intermittent fasting, for starters – 12:12 or 10:14.
• Add any physical activity to your schedule on a regular basis: walking, running, group or personal training, dancing, swimming, etc.

Preventing insulin resistance can be one of the most powerful ways to stay lean and live a much longer and healthier life.

2. Leptin

Fat secreted leptin controls appetite and helps you feel full. In simple terms, when leptin levels are balanced, you don’t overeat.

Similar to insulin, chronically high leptin levels can cause leptin resistance. When the body becomes resistant to leptin, the brain no longer recognizes the signal of the hormone and mistakenly believes that you are hungry, even if in fact the body already has enough energy stored up.

Other possible causes of leptin resistance include chronic inflammation and increased levels of free fatty acids in the bloodstream.

For most people who struggle with leptin resistance, getting themselves to overcome the hunger signal caused by this condition is VERY difficult.

What can you do?

1. Avoid processed foods: Highly processed foods can compromise intestinal integrity and cause inflammation. As we have said, inflammation is closely linked to the development of leptin resistance.
2. Add soluble fiber: Eating soluble fiber can improve gut health and protect against obesity.
3. Add Protein: Eating plenty of protein can help you lose weight.
4. Exercise: Physical activity can help reverse leptin resistance.
5. Sleep: Lack of sleep is closely linked to the problem of disturbing normal leptin levels.

While there is no easy way to cure leptin resistance, you can make long-term lifestyle changes that will make a difference in how you feel right from the start.

3. Ghrelin

Ghrelin is a hormone produced in the intestines. It is often referred to as the hunger hormone because ghrelin’s main function is to increase appetite. It is he who stimulates you to eat more and accumulate fats.

In addition, it affects your sleep/wake cycle, taste sensations, and carbohydrate metabolism.

Ghrelin is produced in the stomach and released when the stomach is empty. It enters the bloodstream and affects the part of the brain known as the hypothalamus, which regulates your hormones and appetite. The higher the level of ghrelin, the hungrier you become. That’s why if you’re looking to lose weight, lowering your ghrelin levels can be helpful.

Ghrelin levels usually rise before meals when your stomach is empty. It then declines shortly after the stomach is full.

No matter how much you weigh, ghrelin levels usually go up when you go on a diet. This is your body’s natural reaction to trying to protect you from hunger and exhaustion.

During a strict diet, your appetite increases and levels of the “satiety hormone” leptin decrease. The metabolic rate also tends to drop significantly, especially if you restrict calories for an extended period of time.

For obvious reasons, this mechanism can make losing weight much more difficult.

What can you do?

Ghrelin seems to be a hormone that cannot be controlled. However, there are a few habits you can adopt to keep it healthy:

1. Avoid extremes: both obesity and anorexia throw ghrelin out of balance.
2. Get enough sleep, rest, do not allow a state of complete weakness.
3. Gain muscle mass, do fitness.
4. Eat more protein: Protein increases satiety and reduces hunger.

Protein Sources

• fish and seafood,
• meat and poultry,
• eggs,
• quinoa,
• nuts and seeds,
• legumes and lentils.

The best way to control ghrelin is with a sustainable healthy eating plan. Extreme diets and drastic calorie reduction can negatively impact hormone levels and interfere with normal function.

4. Cortisol

Cortisol is an important steroid hormone that belongs to a class of hormones called glucocorticoids. It is produced by the adrenal glands, located just above the kidneys.

In addition to helping with the stress response, other functions of cortisol include:

• increased blood sugar level;
• reduction of inflammation;
• suppression of the immune system;
• aid in nutrient metabolism.

Cortisol is usually released in close conjunction with your body’s circadian rhythm, with 50-60% released after 30-40 minutes of being awake, and then cortisol levels drop throughout the day.

Cortisol is also released during times of stress. This prepares your body for a potentially dangerous situation. And while this reaction is normal, chronically high cortisol levels can lead to negative side effects:

What can you do?

While there can be many stressors in your life that can potentially increase your cortisol levels, there are several effective ways to manage your cortisol levels.

1. Universal tip – be active and get enough sleep. Physical activity relieves tension and allows you to be more resilient to stress, while healthy sleep ensures quality recovery and hormonal balance.
2. Try to eat mindfully. The Intuitive Eating concept involves total concentration on what and how you eat and how you feel while eating. The easiest way to start practicing mindful eating is to get rid of distractions* while eating. This will allow you to eat more slowly and mindfully, as well as better feel and recognize the signals of hunger and satiety.

* Examples of distractions: phone, TV, laptop, very loud music, book, conversations that distract from food, road (food on the run).

3. Another potential tool for managing cortisol levels is meditation. You can start with a few minutes of measured deep breathing. While inhaling deeply, count the duration of the breath in seconds, pause at the top of the inhalation for the same number of seconds that you inhaled, and exhale for the same number of seconds. Repeat this cycle a couple of times, and if breathing allows, gradually increase the time of inhalation, retention and exhalation, maintaining a ratio of 1:1:1.
   For example: inhale – mentally count to 5, hold – again count to 5, exhale – and again 5 counts. Do at least 5-7 reps.

You can also use any practice that has a relaxing effect on you: a massage, a spa, talking to a loved one, reading, listening to a favorite artist’s album, or a walk in the park.

Conclusion and general recommendations

To get a complete picture of your hormonal health, we highly recommend that you see your doctor. You will need to take a consultation and pass comprehensive tests. In addition to the indicators disclosed in the article, it will also be useful to immediately pass biochemical analysis, female profile (hormones) and thyroid profile. This will help you avoid wrong decisions about the true cause of weight gain and protect yourself from additional danger.

The general recommendations in this article may be useful as a preventive measure.

Sources

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5 common causes and what to do about them

Weight gain during menstruation is common. Many people face this problem. On the one hand, this is completely normal. On the other hand, it is not very pleasant when the usual clothes literally stop fastening. Why do we get fat every month and can something be done about it so as not to gain weight?

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Menstruation

premenstrual syndrome

Signs of PMS (premenstrual syndrome) are well known to many – these are chest pains, and bloating, and that same weight gain. There is nothing pleasant in waking up in the morning and, besides the periods themselves, finding out that you no longer fit into jeans. Literally overnight! This is due to the fact that the body retains fluid more strongly, you swell, and these edema give you those very 1-2 extra pounds.

Do not self-medicate! In our articles, we collect the latest scientific data and the opinions of authoritative health experts. But remember: only a doctor can diagnose and prescribe treatment.

How much weight gain is normal during menstruation?

There are no clear criteria, but most women gain 0.5–3 kg. These extra pounds are distributed in different ways. Someone notices that they are evenly distributed throughout the body, someone sees that they accumulate in the abdomen or, for example, the upper arms.

The weight change itself usually occurs at the very beginning of menstruation, often even before spotting occurs.

And although this symptom is considered typical, not everyone experiences it. And this means that if weight gain (like other signs of PMS) bothers you a lot, then the best option is not to try folk remedies, but to see a doctor. It is likely that you need to correct something in the body. In addition, lifestyle changes can also play a role.

So, here are 5 reasons why your weight increases during your period.

Hormones

The level of hormones in the body is constantly changing, depending on the phase of the menstrual cycle, they can be either higher or lower. If estrogen is elevated, this can cause the body to become more fluid-retaining. If for some reason the estrogen in your body is already higher than normal, then the tendency to edema will be higher. Progesterone also plays a role, against the background of an increase in its concentration, weight can also increase due to water retention.

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You eat too much

When menstruation starts, we often eat too much. Our appetite drives us to eat tons of food (and we’re not talking about broccoli at all). Often we lean on sweet and salty, as a result we get the expected effect. From the sweet, the weight begins to grow almost before our eyes, and the salty provokes the accumulation of fluid even more.

In general, this can be a little tricky, but try not to overeat ice cream and chips. Instead, eat yogurt and other protein foods. Do you want something sweet? Fruit will help. It’s hard, but real.

You don’t exercise

During menstruation, many people put off exercising until later. Of course, if the bleeding is very strong, then there can be no talk of playing sports. However, in general, menstruation is not an obstacle to playing sports.

Firstly, it will help to remove excess water. Secondly, it promotes the production of endorphins – the hormone of pleasure, which will also have a positive effect on your well-being – not only physical, but also emotional.

You have digestive problems

Due to hormonal changes in your body, you may experience digestive problems. And constipation is one of them. An increase in the concentration of progesterone is to blame here, due to which the intestinal walls begin to contract worse than usual.

As a result, in addition to the usual edema, there is also the severity associated with the fact that you cannot go to the toilet normally. Taking probiotics will help solve or at least alleviate the problem – both in the form of additional complexes (check with your doctor) and as a food component (yogurt and sauerkraut will do here).

You drink too much coffee

Coffee has become an accessory to office life and the salvation of business people who are always suffering from lack of sleep. But an excess of caffeine in the body can cause bloating, discomfort, and weight gain.

By the way, coffee is not the only drink that contains caffeine. Tea is also in this company.