Does meloxicam cause constipation? Learn about the potential side effects, interactions, uses, dosage, and warnings of this generic prescription medication.

Meloxicam Side Effects: How to Manage

Meloxicam (Mobic, Anjeso) is a generic prescription medication used to treat osteoarthritis, rheumatoid arthritis (RA), and juvenile RA. It is available as an oral tablet and capsule. As with any drug, meloxicam can cause side effects, some of which are more common than others.

Common Side Effects of Meloxicam

Some of the more common side effects reported by people who took meloxicam in clinical trials include:

• Upper respiratory infection, such as the common cold
• Flu-like symptoms, such as fever, chills, or sore throat
• Digestive problems, such as abdominal pain, constipation, and diarrhea
• Headache*

*For more information about this side effect, see “Side Effect Specifics” below.

Mild Side Effects of Meloxicam

Mild side effects that have been reported with meloxicam use include:

• Mild infections, such as urinary tract infection (UTI) and upper respiratory infection
• Flu-like symptoms, such as fever, chills, or sore throat
• Dizziness
• Back pain
• Insomnia
• Rash or itchiness
• Sleepiness or drowsiness
• Digestive problems, such as abdominal pain, constipation, and diarrhea
• Weight gain or weight loss*
• Headache*
• Joint pain*
• Mild allergic reaction*

*For more information about this side effect, see “Side Effect Specifics” below.

Serious Side Effects of Meloxicam

Meloxicam may also cause serious side effects. If you develop any of the following symptoms, call your doctor right away or seek immediate medical attention:

• Anemia (low level of red blood cells) – Symptoms can include lightheadedness, pale-looking skin, and shortness of breath.
• High blood potassium level – Symptoms can include nausea, vomiting, shortness of breath, muscle cramps, and heart palpitations.
• Severe skin reactions, such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug rash with eosinophilia and systemic symptoms – Symptoms can include fever, swollen lymph nodes, a painful rash, and blisters or peeling skin around the eyes, mouth, or throat.
• Fluid buildup, which may occur in the face, arms, or legs – Symptoms can include weight gain, shiny or swollen skin, and pain or stiffness around the affected area.
• Kidney damage – Symptoms can include fatigue, nausea, vomiting, loss of appetite, and muscle cramps.
• Liver damage – Symptoms can include fatigue, nausea, diarrhea, pain in the upper right abdomen, and jaundice.
• High blood pressure, which doesn’t typically cause symptoms.
• Heart problems*
• Digestive system problems*
• Severe allergic reaction*

*Meloxicam has a boxed warning for this side effect, which is the most serious warning from the FDA.

Side Effect Specifics

Meloxicam may cause certain side effects, such as headaches, weight changes, joint pain, and allergic reactions, that require more detailed information:

Headaches

Headaches are a common side effect of meloxicam. If you experience persistent or severe headaches while taking this medication, talk to your doctor. They may be able to recommend ways to manage the headaches, such as adjusting your dosage or trying over-the-counter pain relievers.

Weight Changes

Meloxicam can sometimes cause weight gain or weight loss. If you notice any significant changes in your weight while taking this medication, discuss it with your doctor. They may be able to help determine the cause and recommend ways to manage it.

Joint Pain

Some people report experiencing joint pain while taking meloxicam. If this occurs, talk to your doctor. They may be able to suggest ways to alleviate the pain, such as adjusting your dosage or trying a different medication.

Allergic Reactions

Meloxicam can cause mild allergic reactions, such as rash or itchiness. However, it can also cause more serious allergic reactions, which are considered a boxed warning for this medication. If you experience any signs of an allergic reaction, such as difficulty breathing, swelling, or a severe rash, seek immediate medical attention.

Meloxicam Side Effects in Children

Meloxicam is approved to treat juvenile rheumatoid arthritis in children weighing at least 60 kilograms (about 132 pounds). Most side effects are expected to be the same as in adults, but the following side effects may be more common in children:

• Certain digestive problems, such as diarrhea, vomiting, and abdominal pain
• Fever
• Headache

If you have any concerns about your child’s use of meloxicam, be sure to discuss them with their doctor.

Reporting Side Effects

If you develop a side effect while taking meloxicam and want to report it to the FDA, you can visit MedWatch.