How does Effexor affect body weight. What are the common side effects of Effexor. Can Effexor cause significant weight changes. How to manage weight while taking Effexor. What are the alternatives to Effexor for depression and anxiety treatment. How does Effexor compare to other antidepressants in terms of weight gain. What should patients know about Effexor and weight management.

Understanding Effexor: An Overview of the Antidepressant

Effexor, known generically as venlafaxine, is a widely prescribed antidepressant belonging to the class of medications called Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs). First approved by the FDA in 1993, Effexor has become a go-to treatment for various mental health conditions, primarily major depressive disorder, generalized anxiety disorder, and panic disorder.

Available in both immediate-release and extended-release formulations (Effexor XR), this medication works by altering the balance of neurotransmitters in the brain, specifically serotonin and norepinephrine. By increasing the levels of these crucial chemical messengers, Effexor aims to improve mood, reduce anxiety, and alleviate other symptoms associated with depression and anxiety disorders.

Key Indications for Effexor

• Major Depressive Disorder (MDD)
• Generalized Anxiety Disorder (GAD)
• Panic Disorder
• Social Anxiety Disorder
• Depression associated with Bipolar Disorder

While Effexor has proven effective for many patients, it’s crucial to understand its potential side effects, particularly the concern of weight gain, which we’ll explore in depth throughout this article.

The Weight Gain Conundrum: Examining Effexor’s Impact

One of the most pressing concerns for patients considering or currently taking Effexor is its potential effect on body weight. Does Effexor cause weight gain? The short answer is that it can, but the relationship between Effexor and weight changes is complex and varies from person to person.

Clinical studies have shown that weight gain is indeed a common side effect of Effexor, along with many other antidepressants. One notable study found that more than 55% of patients using newer antidepressants, including Effexor, experienced weight gain over treatment periods ranging from 6 to 36 months. Even more striking, over 40% of participants gained 7% or more of their baseline weight.

Factors Contributing to Weight Gain on Effexor

1. Changes in appetite: Effexor may increase appetite in some individuals, leading to increased calorie intake.
2. Metabolic changes: The medication can affect how the body processes and stores fat.
3. Fluid retention: Some patients may experience edema or water retention, contributing to weight gain.
4. Lifestyle changes: Improved mood may lead to changes in eating habits or physical activity levels.
5. Individual variability: Genetic factors and personal physiology play a role in how one’s body responds to the medication.

It’s important to note that while weight gain is a possibility, not everyone taking Effexor will experience this side effect. Some individuals may even lose weight, particularly if depression had previously led to increased appetite or comfort eating.

Comparing Effexor to Other Antidepressants: Weight Gain Profiles

When considering Effexor and its potential for weight gain, it’s helpful to understand how it compares to other antidepressants. While newer classes of antidepressants like SNRIs and SSRIs are generally considered to have a lower risk of weight gain compared to older medications, the risk still exists.

SSRIs vs. SNRIs: A Weight Gain Comparison

• SSRIs (e.g., Prozac, Zoloft, Lexapro): Generally associated with modest weight gain
• SNRIs (e.g., Effexor, Cymbalta): Variable weight effects, with some studies showing similar or slightly lower risk compared to SSRIs
• Older antidepressants (e.g., tricyclics, MAOIs): Typically associated with more significant weight gain

Within the SNRI class, Effexor’s weight gain profile is comparable to other medications like duloxetine (Cymbalta) and atomoxetine (Strattera). However, individual responses can vary greatly, and what causes weight gain in one person may not affect another.

Managing Weight While Taking Effexor: Practical Strategies

For patients concerned about potential weight gain while taking Effexor, there are several strategies that can help mitigate this side effect:

1. Regular monitoring: Keep track of your weight and discuss any significant changes with your healthcare provider.
2. Balanced diet: Focus on nutritious, whole foods and practice portion control.
3. Regular exercise: Engage in both cardiovascular activities and strength training to support metabolic health.
4. Hydration: Ensure adequate water intake to help manage fluid retention and support overall health.
5. Sleep hygiene: Maintain a consistent sleep schedule, as poor sleep can contribute to weight gain.
6. Stress management: Incorporate stress-reduction techniques like meditation or yoga into your routine.

Is it possible to prevent weight gain while on Effexor? While complete prevention may not be possible for everyone, these strategies can significantly reduce the risk and severity of weight gain. It’s crucial to work closely with your healthcare provider to monitor your progress and adjust your treatment plan as needed.

Beyond Weight Gain: Other Common Side Effects of Effexor

While weight gain is a significant concern for many patients, it’s important to be aware of other potential side effects associated with Effexor. Understanding these can help patients make informed decisions about their treatment and manage their expectations.

Common Side Effects of Effexor

• Nausea and gastrointestinal disturbances
• Headache
• Dry mouth
• Insomnia or changes in sleep patterns
• Sexual dysfunction (e.g., decreased libido, difficulty achieving orgasm)
• Increased sweating
• Dizziness
• Fatigue
• Anxiety or agitation, particularly in the initial weeks of treatment

How long do Effexor side effects typically last? Many side effects are transient and tend to improve as the body adjusts to the medication, usually within the first few weeks of treatment. However, some side effects, including weight changes, may persist longer or develop over time.

It’s crucial to communicate openly with your healthcare provider about any side effects you experience. In some cases, adjusting the dosage or switching to a different medication may be necessary to find the right balance between symptom relief and manageable side effects.

Alternatives to Effexor: Exploring Other Treatment Options

For patients who find the potential for weight gain or other side effects of Effexor concerning, there are numerous alternative treatments available for depression and anxiety. These options may include other medications, psychotherapy, or a combination of both.

Medication Alternatives

• Other SNRIs: Duloxetine (Cymbalta), Desvenlafaxine (Pristiq)
• SSRIs: Fluoxetine (Prozac), Sertraline (Zoloft), Escitalopram (Lexapro)
• Atypical antidepressants: Bupropion (Wellbutrin), Mirtazapine (Remeron)
• Newer antidepressants: Vortioxetine (Trintellix), Vilazodone (Viibryd)

Non-Medication Approaches

1. Cognitive Behavioral Therapy (CBT)
2. Interpersonal Therapy
3. Mindfulness-Based Therapies
4. Electroconvulsive Therapy (ECT) for severe cases
5. Transcranial Magnetic Stimulation (TMS)

What factors should be considered when choosing an alternative to Effexor? The decision to switch medications or explore alternative treatments should be made in consultation with a healthcare provider. Factors to consider include the severity of symptoms, past treatment responses, individual health profile, and personal preferences.

The Role of Lifestyle Modifications in Managing Depression and Anxiety

While medication can be a crucial component of treatment for many individuals with depression or anxiety, lifestyle modifications can play a significant role in managing symptoms and potentially reducing the need for medication or mitigating side effects like weight gain.

Key Lifestyle Factors for Mental Health

• Regular physical exercise
• Balanced, nutrient-rich diet
• Adequate sleep and consistent sleep patterns
• Stress management techniques (e.g., meditation, deep breathing exercises)
• Social connections and support systems
• Engaging in meaningful activities and hobbies
• Limiting alcohol and avoiding recreational drugs
• Exposure to natural light and nature

Can lifestyle changes alone be effective in treating depression and anxiety? While lifestyle modifications can be powerful tools in managing mental health, they are often most effective when combined with professional treatment, especially for moderate to severe cases. However, for mild cases or as a preventive measure, lifestyle changes can sometimes be sufficient to maintain good mental health.

Integrating these lifestyle factors into your daily routine can not only help manage the symptoms of depression and anxiety but may also contribute to better overall health, potentially reducing the impact of medication side effects like weight gain.

Long-Term Considerations: Effexor and Chronic Use

For many individuals with chronic depression or anxiety disorders, long-term use of antidepressants like Effexor may be necessary. Understanding the implications of prolonged use is crucial for patients and healthcare providers alike.

Long-Term Effects of Effexor

1. Sustained weight changes: Weight gain may continue or stabilize over time
2. Potential for sexual side effects to persist
3. Risk of discontinuation syndrome if medication is stopped abruptly
4. Possible emotional blunting or reduced emotional range in some individuals
5. Potential impact on bone density, particularly in older adults
6. Interactions with other medications or health conditions over time

How often should patients on long-term Effexor treatment be monitored? Regular check-ups with a healthcare provider are essential for patients on long-term Effexor treatment. These appointments should occur at least every 3-6 months, or more frequently if needed, to assess the ongoing effectiveness of the medication, monitor side effects, and make any necessary adjustments to the treatment plan.

It’s important to note that while long-term use of Effexor is generally considered safe and effective for many patients, individual experiences can vary. Some patients may find that their need for medication changes over time, while others may require ongoing treatment to maintain their mental health.

Strategies for Long-Term Success with Effexor

• Regular medication reviews with your healthcare provider
• Ongoing monitoring of weight and other potential side effects
• Combining medication with psychotherapy for comprehensive treatment
• Developing coping strategies and life skills to complement medication
• Maintaining open communication about any changes in symptoms or side effects
• Considering periodic reassessment of the need for continued medication

By taking a proactive approach to long-term Effexor use, patients can maximize the benefits of their treatment while minimizing potential drawbacks. This balanced approach can lead to better overall outcomes and improved quality of life for those managing chronic depression or anxiety disorders.

Does Taking Effexor Cause Weight Gain?

People who are struggling with symptoms of common mental health conditions like depression or anxiety may be interested in seeking help for their condition. However, they may be concerned about side effects reported with some of these drugs. 

Antidepressant medications are commonly associated with weight gain regardless of which drug class they belong to, and weight gain is a significant concern for many patients. While newer classes of antidepressants such as selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs) are less commonly associated with weight gain than older classes of antidepressants like tricyclic antidepressants and monoamine oxidase inhibitors (MAOIs), weight gain can still occur. SSRI antidepressants include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft). 

Other examples of SNRIs include duloxetine (Cymbalta) and atomoxetine (Strattera). Effexor is a popular brand name SNRI that is commonly prescribed by healthcare professionals for the treatment of depression and anxiety symptoms, but does taking Effexor cause weight gain? 

What is Effexor?

Effexor is a brand-name prescription drug that is also available under the generic name, venlafaxine. Effexor is available in both immediate-release and extended-release formulas; the extended release version of the drug is called Effexor XR. 

The medication was first approved by the U.S. Food and Drug Administration (FDA) in 1993 for the treatment of major depressive disorder, which is sometimes referred to as clinical depression  Effexor is available by prescription only and belongs to a class of drugs called serotonin norepinephrine reuptake inhibitors (SNRIs), which are a relatively new class of antidepressants that are commonly used to treat mental health conditions such as depression and anxiety.

What is Effexor used to treat?

Effexor is approved by the FDA to treat several mental health conditions, including clinical depression (also known as major depressive disorder), generalized anxiety disorder (also known as GAD), and panic disorder. Effexor can also be prescribed for the treatment of social anxiety disorder and depression associated with bipolar disorder. 

The drug works by acting on the reuptake of serotonin and norepinephrine in the brain, which helps to increase the levels of these important neurotransmitters. When the balance of serotonin and norepinephrine stabilizes in the brain, patients commonly experience improved mood and reduced symptoms. 

Treatment Options for Depression, Anxiety, and Other Mental Health Ailments

Does taking Effexor cause weight gain?

Antidepressants have a bad reputation when it comes to causing weight gain, and unfortunately, Effexor is no exception. Clinical trials have shown that Effexor is commonly associated with weight gain. 

In one study, more than 55 percent of patients using newer antidepressants, including Effexor, gained weight over the course of treatment that lasted between 6 and 36 months. More than 40 percent of the study participants gained at least 7 percent or more weight compared to their baseline. 

The study found that Effexor and other antidepressant drugs were associated with significant weight gain. 

Other studies have reported finding similar results, with the majority of SSRIs and SNRIs associated with body weight gain as a common side effect. This may be caused by an increase in cravings for carbohydrate-rich foods and a slight increase in appetite that adds weight over time. It does not significantly affect blood sugar levels. Effexor can also cause a drastic decrease in appetite, leading to unhealthy weight loss. 

What side effects are associated with Effexor?

In addition to causing potential weight gain, Effexor is also associated with a number of other common and less common side effects.  

Common side effects associated with Effexor include:

• Headache

• Drowsiness

• Insomnia

• Dizziness

• Weakness 

• Tremors

• Dry mouth

• Nervousness

• Increased sweating

• Blurred vision

• Ejaculation disorder

• Abnormal ejaculation

• Increased blood pressure

• Nausea

• Constipation 

• Loss of appetite

• Weight changes

• Constipation

Effexor is also associated with side effects that are less common but are potentially serious. If you experience any of the following uncommon but potentially serious side effects, you should seek medical attention right away:  

• Rash

• Seizures

• Itching

• Fast, pounding, or irregular heartbeat

• Unusual bruising or bleeding

• Chest pain

• Hives

• Hallucinations

• Fever

• Problems with coordination

• Trouble breathing or swallowing (may be the result of an allergic reaction)

• Serotonin syndrome

• Muscle rigidity

• Coma

• Interstitial lung disease (very rare)

Summary

Like other antidepressants, Effexor is commonly associated with weight gain. More than 50 percent of patients taking antidepressants like Effexor report weight gain while taking their medication. Other side effects associated with Effexor commonly include drowsiness, dizziness, nausea, and vomiting. Seek medical advice to see if Effexor is right for you. 

Patients who are taking Effexor can save on the cost of their prescription drugs by using a pharmacy discount card from USA Rx.

Sources: 

https://www.webmd.com/drugs/2/drug-1836/effexor-oral/details 

https://pubmed.ncbi.nlm.nih.gov/25467076/ 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850471/

Advertisement

Instant Offer from a USA Rx Partner

Effexor Weight Gain & Metabolism

A woman is talking to her doctor.

Image Credit: megaflopp/iStock/Getty Images

Venlafaxine, sold under the brand name Effexor, is an anti-depressant medication. Effexor is a serotonin-norepinephrine reuptake inhibitor, or SNRI. It’s a class of drugs that target the neurotransmitters serotonin and norepinephrine in your brain. Although Effexor can cause weight gain, it is less likely to cause weight gain compared to other anti-depressants. Consult your physician if you are experiencing any side effects while on Effexor.

How Effexor Works

Effexor is used to treat major depression. An imbalance of a neurotransmitter, like serotonin or norepinephrine, can cause depression. In healthy adults, when a message travels down one nerve cell to another, neurotransmitters are released into the space between the nerve cells. When enough neurotransmitters are released to reach the second nerve cell, the message continues on its way. The initial nerve cell reabsorbs any remaining neurotransmitters in a process called reuptake. Effexor, and other SNRIs, help to block the reuptake of serotonin and norepinephrine so that more will remain in the gap between nerve cells, which helps to ensure that messages continue to travel through the brain.

Effexor and Weight Gain

Although Effexor is less likely to cause weight gain than other anti-depressants, it is still possible to see an increase in weight while taking the medication. Weight gain was a reported side effect in at least 1 percent of the people taking the medication, however the exact percentage amount is not known, according to eMedTV. com. It is unclear if Effexor causes the weight gain or if the weight gain is a symptom of depression. One of the criteria of major depression, according to the “Diagnostic and Statistical Manual of Mental Disorders,” is a significant change in weight.

The role of most antidepressants is still largely unknown, but some research suggests that antidepressants can affect metabolism. A study published in “L’Encephale” reviewed the past research on different psychotropic drugs and how they interact with metabolism. Researchers speculate that anti-depressants, including Effexor, might interfere with central nervous functions that regulate energy balance. The research also speculates that some anti-depressants decrease the resting metabolic rate. However, the researchers indicate that more studies need to be done on metabolism and anti-depressants to learn the exact role medication plays in the metabolic process.

Effexor Side Effects

Effexor has been studied in a number of clinical trials for side effects. Some common side effects of the medication include nausea, headaches, drowsiness, dizziness and insomnia. Other side effects include changes in appetite and anxiety and sexual and gastrointestinal problems. Effexor can potentially have serious side effects. It can increase blood pressure, cause high cholesterol, cause confusion and strange thoughts. In children, adolescents and young adults, Effexor increased the risk of suicidal thinking and behavior compared to placebo.

Effexor May Cause Anorexia – Carey Danis & Lowe

The relatively popular antidepressant drug Effexor is said to be causing another side effect that most people hadn’t banked on. Some doctors are saying that Effexor actually causes anorexia.

It is well known that most antidepressants can come with a slew of negative side effects including severe allergic reactions, nausea, diarrhea, mood swings, insomnia, hallucinations and seizures. They also come with less serious ones, such as drowsiness, dizziness, nervousness, weird dreams, sweating, blurred vision, dry mouth, mild nausea, constipation, lower sex drive, impotence and difficulty having an orgasm.

However, it is not often reported that some people are using drugs like Effexor more as appetite suppressants than in combating depression. Since doctors can only go on what their patients tell them about their “symptoms,” it is easier and easier for new patients to get their hands on these pills.

Effexor now is being directly associated with anorexia (not to be confused with the eating disorder anorexia nervosa). This form of anorexia is caused by a loss or decrease in appetite and is one of the most common side effects of taking Effexor. While just 8 percent of those taking Effexor for depression experienced anorexia compared to 20 percent in those taking it for social anxiety disorder, the effect is still alarming.

The anorexia side effect has caused some people to refuse taking Effexor. Even though Effexor poses many of the same risks that Paxil does, not all patients deem the anorexia as a bad thing. This can also pave the way for patients taking Effexor to ignore the extreme risks of addiction that Effexor poses, as well as the potential that exist for patients to abuse the drug in an effort to lose weight. One thing that most people don’t know until they are on Effexor is that it is the hardest drug to come off of. The withdrawal effects are dastardly, causing many doctors to only prescribe it for patients that are expected to stay on the drug long-term.

How to Lose Weight While on Effexor XR

If you or someone you love is experiencing depression, chances are your doctor has broached the idea of controlling the condition with medication. While this can be a very helpful treatment, it’s important to familiarize yourself with any prescription drugs and their potential side effects.

In the case of Effexor XR, an antidepressant, weight change is one of the anticipated side effects. According to an FDA clinical trial, 7 percent of people with depression who were treated with the medication experienced a weight loss of 5 percent or more.

That can be helpful if you’re trying to lose weight that you gained prior to starting the medication. Or if you do find yourself gaining weight while on the medication, there are several things you can do to stop the pounds from creeping on.

What Is Effexor XR?

Effexor XR, a time-release capsule, and Effexor, its nontime-release tablet counterpart, have been produced since the late 1990s by Pfizer Inc. to treat the symptoms of depression and several forms of anxiety.

The generic form is called venlafaxine. The prescription medication works with serotonin and norepinephrine, chemicals produced in the brain. The pharmaceutical community calls it a serotonin-norepinephrine reuptake inhibitor.

Read more: 10 Habits Keeping You Depressed (and How to Break Them)

Effexor Side Effects

How to Lose Weight While on Methotrexate

According to Pfizer, there are several common side effects that may occur when taking Effexor XR. They include:

• Unusual dreams
• Sexual problems
• Loss of appetite, constipation, dry mouth, nausea or diarrhea 
• Fatigue
• Difficulty sleeping
• Tremor or shaking
• Dizziness or blurred vision
• Increased heart rate or feeling anxious
• Headache
• Sweating

If you’re taking this medication and experience any of the symptoms listed above, be sure to speak to your physician about them.

Weight Changes and Effexor XR

Sixty to 80 percent of users of any antidepressant enjoy an improved outlook on life. That alone can affect your appetite. Plus, the brain chemicals with which antidepressants are designed to interact have a bearing on the amount of weight you might gain.

However, a serotonin-norepinephrine reuptake inhibitor (SNRI) like Effexor XR causes less weight gain in the long term than other antidepressants, such as citalopram (also known as Celexa) or mirtazapine (Remeron). And because Effexor XR works with your natural serotonin, it can actually cause weight loss in some people.

Seratonin, a chemical that’s found in the brain, activates neurons that curb your appetite. In addition, it also blocks other neurons that may cause you to feel hungry. This dual effect may be one of the reasons for weight loss while on Effexor XR. In addition, any positive effects the drug has on your overall outlook or mood may help you to become more active and lose any pre-existing excess weight.

Read more: 10 Ways Changing How You Think Promotes Weight Loss

Tips for Healthy Weight Loss

No Energy, Lack of Stamina and Tired

Even while on Effexor XR, maintaining a healthy weight is an achievable goal. Try these helpful tips to assist you in properly managing your weight.

1. Eat a Healthy Diet

One of the most important factors in losing weight is healthy eating. The Mayo Clinic recommends that your diet include a variety of different food groups, including fruits, vegetables, whole grains, low-fat dairy items and lean proteins.

In addition, foods that are high in saturated fats, sodium or cholesterol should be avoided. Resisting the urge to buy unhealthy foods at the grocery store will help you abstain from them later on when you are hungry.

2. Be Active Every Day

Incorporating exercise into your daily life can also help you burn excess calories and keep your weight in check. The American College of Sports Medicine (ACSM) suggests that adults get at least 150 minutes of moderate-level cardiovascular exercise each week. This can include walking, stationary biking or using an elliptical.

The ACSM also recommends strengthening each major muscle group two to three times per week using weights or resistance machines. Varying the type and intensity of your workouts prevents your body from adapting to the exercise and increases its effectiveness.

What’s more, there’s evidence to suggest that regular exercise may also help stave off the symptoms of depression. That’s because higher-intensity exercise may cause your body to release chemicals called endorphins, which help enhance your overall mood. In addition, sustained exercise over time may improve your brain function and outlook by helping your brain’s nerve cells grow and make new connections.

Read more: 9 Things You DON’T Have to Do to Lose Weight

3. Get Plenty of Sleep

Getting the appropriate amount of sleep each night helps your body recover from the previous day and can assist you in losing weight. According to the National Sleep Foundation, the average adult should be getting between seven and nine hours of sleep per night.

Stimulants like caffeine, which is found in coffee, tea and energy drinks, should be avoided because they can interfere with your ability to rest. In addition, it’s a good idea to put down electronic devices like phones or tablets before bedtime: They can disturb the body’s circadian rhythm.

4. Talk to Your Doctor

One of the best allies you have in losing weight while on an antidepressant is your physician. While you may feel nervous or uncomfortable about discussing this topic, your doctor can help to determine if other conditions may be impacting your weight fluctuations.

Thyroid issues, hormonal imbalances or vitamin and mineral deficiencies could be to blame. In addition, your physician may be able to modify your medication’s dose or refer you to someone who specializes in mental health disorders like depression.

Antidepressants cause minimal weight gain

ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. 

Antidepressants have helped millions of people cut through the dark fog of depression. Many others try these medications but stop taking them, often because of side effects such as weight gain. A study from a Harvard-based team shows that the amount gained is usually small, and that it differs little from one antidepressant to another.

Earlier studies linking antidepressant use to weight gain were usually small and short. This one, led by researchers with Massachusetts General Hospital’s Center for Experimental Drugs and Diagnostics, included more than 19,000 men and women and lasted for a year.

Using electronic health records, the researchers identified men and women who took an antidepressant for at least three months. Medications used included amitriptyline (Elavil), bupropion (Wellbutrin), citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac), mirtazapine (Remeron), nortriptyline (Pamelor), paroxetine (Paxil), venlafaxine (Effexor), or sertraline (Zoloft). They also identified another 3,400 people who took some other type of medication for a non-depression ailment. Each person’s weight was checked every three months for a year.

The researchers chose citalopram as a reference, because earlier studies suggested that it is “average” when it comes to weight gain. In this study, the weight gain experienced by people taking citalopram averaged one to two pounds. Compared to citalopram, the weight gain linked to other antidepressants was small.

Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Amitriptyline and nortriptyline are older drugs. Because newer drugs tend to have fewer side effects, those two aren’t prescribed as frequently. At the other end of the spectrum, citalopram caused the most weight gain. Even so, the differences between the drugs were small. The results of the study were published in JAMA Psychiatry.

Not everyone taking antidepressants gained weight. Some actually lost a few pounds.

Tip for choosing an antidepressant

The results of this study indicate that worries about weight gain shouldn’t influence the choice of antidepressant for most people. One antidepressant is generally as effective as another. If you need to choose an antidepressant, let cost and potential side effects be your guide.

Many antidepressants are available as generics. Generics work as well as brand name drugs, but cost less.

Here are some tips for choosing a treatment based on common side effects:

• Sexual side effects, such as difficulty having an orgasm. Bupropion may be less likely to cause this side effect. It’s also the one associated with the least amount of weight gain.
• Sleepiness. Some antidepressants make you sleepy. If you have trouble falling asleep or staying asleep, taking one of these before bed, like trazodone, might be a good idea. Paroxetine is another good choice.
• Decreased energy level. No antidepressant leads the pack in terms of being more stimulating. Perhaps bupropion or fluoxetine might be a good first choice.

If you start taking an antidepressant, don’t expect to see a major improvement right away. It often takes 6 to 8 weeks to see a response to an antidepressant. And don’t give up if the first one doesn’t work. Trying a different one may do the trick.

Another option to consider is psychotherapy, especially if the first drug doesn’t work. People who do not respond to the first antidepressant can often do as well with talk therapy as they would with another drug.

Keep in mind that a small number of people have a condition called atypical major depression. Instead of the more usual problems of decreased appetite and difficulty sleeping, their depression causes an increased appetite and sleeping too much. This leads to weight gain regardless of drug therapy. For them, it’s probably best to stay away from an antidepressant that causes even more weight gain.

As a service to our readers, Harvard Health Publishing provides access to our library of archived content.
Please note the date of last review or update on all articles. No content on this site, regardless of date,
should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

Commenting has been closed for this post.

Just one mg at a time | Life and style

For the past 10 months I’ve been taking Efexor XL (Venlafaxine), the much-hyped, wonder-drug antidepressant. I was put on this medication to treat various symptoms of anxiety and depression: panic attacks, chronic fatigue, insomnia, loss of appetite, poor concentration, no interest in going out, crying over the slightest thing, and worst of all, thoughts of killing myself.

The first few days on Efexor XL I felt like I’d been fitted with an IV drip that pumped freshly made espresso into my bloodstream. My GP had warned that the drug might have this effect: ‘You might hit the roof on this stuff, let’s be careful.’

I not only hit the roof, I went into orbit. I couldn’t sleep. I couldn’t sit still. I had to constantly be doing something. And then, thankfully, this amphetamine-like buzz wore off and the business of rewiring my brain got under way.

As the medication stabilised my mood, erased all traces of panic attacks, dulled my reaction to anxious thoughts, removed my tendency to obsess, kick-started an era of prolific work, turned me into a socialite, induced nights of perfect sleep and banished all thoughts of suicide, the side-effects came on. The constipation was hardly a surprise: it goes hand in hand with most antidepressants. Weight gain is also a common side-effect. But not on this scale. In the months that followed – despite exercising five times a week and no change from my usual low-fat vegetarian diet – I gained 25lb.

I launched two-hour sessions at the gym, burning off 1,000 calories at a time, and still the scales kept creeping higher. Then there was the sweating. At first I thought it was the weight gain. But then I scoured the web and found dozens of posts from fellow Efexor-heads saying they were sweating like the world had turned into one big sauna. In the mildest of yoga classes, I found myself dripping.

Mentally, there were problems, too. Overnight I turned into a caricature of a stoner. I forgot things, arrived days early or late for appointments, lost my train of thought mid-sentence and managed to bump into any piece furniture in my path. So why keep taking it, you ask. Well, the simple answer is this: I felt better. I was prepared to have myself morphed into a stoned, sweaty, constipated beach ball if it meant no more panic attacks, no more excruciating mornings where I couldn’t get out of bed, no more days staring morosely into a blank computer screen.

In January, my GP decided it was time to start weaning me off the medication and cut my dose from 150mg a day to 75mg. Having just spent Christmas in Milan, I was still high on la dolce vita and willing to give it a go. After the first few days everything started going a bit Memento, the whole sequence of side-effects unfolding in reverse.

I stopped bumping into furniture.

I became dazzlingly lucid. I stopped sweating so much. I lost 5lb in 10 days. And then the end of my constipation announced itself in a never-ending series of dashes to the bathroom. By this point I felt like a slowly deflating beach ball. All the oomph was oozing out of me, too. My brain was wired up to a dimmer switch and someone was turning it down, down, down. A decent night’s sleep was the first thing to go. I lay awake obsessing about the blind woman I’d seen in the supermarket that day, wondering how she coped, hoping there was somebody who loved her and took care of her. Or I lay awake obsessing about the three little girls my wife and I sponsor in Central America and whether they had had the medical treatment they were due. Confusingly, the more tired I got, the faster my brain seemed to be going. Thoughts were taking off 10 at a time. And then other prominent edifices in Efexor-land crumbled, too: seeing friends started feeling like a chore again; I stopped going to the gym because it required too much effort; I had a bright blazing panic attack while out shopping, and instead of working I spent entire days making coffee and gazing absent-mindedly out the window. By the third week on 75mg a day, my wife looked exhausted and ordered me to go back and see my GP. Pronto.

Alarmed to see that I had gone from looking like a relaxed, healthy poster-boy for the Italian lifestyle to resembling Michael Keaton in Beetlejuice in less than a month, she said I clearly wasn’t ready to start coming off the medication and restored my dose to 150mg a day. Within seven days all was fine again. I was piling the pounds on, sweating like a malaria victim and crashing into chairs and tables.

Just like the old days. Except I was sick of being on this medication.

So now I’ve been on 150mg a day of Efexor XL for 10 months and I’ve come to accept that the side-effects are a fair trade for not feeling like that. But I do want to get off this drug. So why the severe reaction to tapering off? Was it really some kind of cold-turkey scenario? Or was it all in my mind?

According to Mind, ‘Withdrawal or discontinuation reactions can occur with all major types of antidepressants.’ The Royal College of Psychiatrists concurs: ‘Studies have shown that up to a third of people have withdrawal symptoms for a short time when they stop antidepressants. These include flu-like symptoms, anxiety, dizziness, vivid dreams, or sensations that feel like electric shocks.’ Since this was my sixth episode of anxiety with depression that needed medical treatment, I’m no stranger to coming on and off medication.

Having taken the antiquated tricyclic antidepressant Prothiaden numerous times, as well as the SSRI antidepressant Citalopram, I can vouch that I’ve always had problems tapering off. Granted I have a disposition towards dependency (I’m a recovering alcoholic), but plenty of people without addiction issues report similar problems with getting off antidepressants. The main problem is that these drugs create an artificial reality, and going back to ‘the real world’ after a season in a parallel chemical universe is both a shock and a letdown. Go on and off antidepressants enough times and you end up having no idea what you should naturally feel like. Nowadays, my normal is a medicated normal. Having lived a chemically enhanced life, the tape counter of my natural self can never be set back to zero again.

When coming off antidepressants, my biggest fear is always that another episode is lurking around the corner and that I’ll again have no choice but to take Efexor XL, or whatever the new miracle drug de jour is. I’m not alone in feeling this way. My friend April went through the same thing last year while weaning off Wellbutrin. ‘When I stop taking the pills, I always hope that it won’t re-emerge to cripple me. Only it does, each time more severe than the last. The months go by, then I see the doctor, teary-eyed, and begin a cycle of medication again. It’s like a carousel; sometimes I’m on, sometimes I’m off. Years pass and I’ve been on and off medication eight times, always ripped in two by the desire to end the depression versus the desire to be pill-free.’ Ill again, she was prescribed Efexor XL six weeks ago and is now feeling better.

By the end of the summer, I hope to be medication-free. Aside from trusting your GP to safely guide you off the medication, there’s no fix-all solution. The dose needs to be lowered both incrementally and slowly, and the patient’s progress monitored on a regular basis. In preparation for the tapering off, I am in training. Each week I take three yoga classes – Kundalini, Astanga and Hatha – as well as working out at the gym and doing Pilates. I’m also nurturing my spiritual self, drawing strength and wisdom from the Bhagavad-Gita, the Kabbalah, Lao-Tze’s Tao Te Ching, Confucius’s Analects, the teachings of the Dalai Lama, The Tibetan Book of the Dead, St Augustine’s Confessions, the Koran and Patanjali’s Sutras.

As with conquering a dependence on anything, it requires a backbone of spirituality to break free. Otherwise you’ve got nothing to build on. As Lao-Tze so wisely said: ‘A journey of a thousand miles begins with a single step.’ Mine, according to my GP, will begin with dropping to 112.5mg for a month.

Effexor Side Effects | Birth Defects, Withdrawal and Other Risks

The antidepressant Effexor (venlafaxine) is designed to boost brain levels of serotonin and norepinephrine, important neurotransmitters that can elevate energy levels, alertness and positive feelings. But in some people, the drug may worsen depression, trigger insomnia and mania, or lead to a heightened risk of suicidal thoughts and behaviors.

Effexor — which is only available in its generic form, venlafaxine, or in the extended-release version of the drug, Effexor XR — can cause other serious side effects including:

• Dangerous elevations in serotonin levels (Serotonin Syndrome)
• Abnormal Bleeding
• Seizures
• Low sodium levels
• Angle Closure Glaucoma
• Elevated blood pressure
• Weight and height changes in pediatric patients
• Decreased appetite and anorexia pediatric patients
• Interstitial lung disease and eosinophilic pneumonia
• Discontinuation syndrome (withdrawal symptoms)

Because Effexor and other antidepressants have also been linked to miscarriage and complications in newborns, patients should notify their doctor if they are pregnant or may become pregnant while taking the drug. Venlafaxine can also be passed from mother to child through breast milk, so women should talk to a physician if they plan to breast feed while taking the drug.

Nausea, Sexual Dysfunction and Other Common Side Effects

Nearly one-third of patients taking Effexor XR in clinical trials developed nausea, the most common side effect of the medication. Other frequently reported side effects included sleepiness and dry mouth, which occurred in approximately 15 percent of patients. About one in 10 patients developed anorexia while taking venlafaxine.

Other common Effexor side effects include:

• Unusual dreams and trouble sleeping
• 
  Constipation and diarrhea
• 
  Vomiting
• 
  Frequent yawning
• 
  Sweating
• 
  Tremor or shaking
• 
  Feeling anxious or jittery
• 
  Headache
• 
  Elevated heart rate
• 
  Dizziness
• 
  Blurred vision

Sexual problems are another common problem associated with antidepressants. In clinical trials, nearly 10 percent of participants who took Effexor reported “abnormal ejaculation.”

A 2010 study in the journal of Psychiatry Investigation found nearly 55 percent of individuals on venlafaxine experienced sexual dysfunction. Symptoms range from decreased sexual desire (libido) to an inability to climax.

Higher Suicide Risk and Dangerous Serotonin Levels

Like most other antidepressant medications, Effexor has been associated with the worsening of depression and the emergence of suicidal thoughts and/or behaviors, or unusual changes in behavior.

In fact, a 2007 study of nearly 200,000 patients found that adults using venlafaxine had a higher risk of suicide and attempted suicide than did patients using other antidepressant medications. But study authors Annalisa Rubino and colleagues noted in the journal BMJ that those patients using venlafaxine also had a “higher burden of suicide risk factors” to begin with.

As with any antidepressant, the risk of suicide is greater during the “early phases of treatment,” according to the drug’s label — and young people under the age of 24 are most at risk.

EXPAND

Effexor’s label includes a black box warning for suicidal thoughts and behaviors.

Venlafaxine has also been linked to a rare but potentially life-threatening elevation in the body’s serotonin levels known as serotonin syndrome.

A person’s risk of serotonin syndrome is higher if he or she is taking other medications — such as triptans, tricyclic antidepressants, fentanyl and St. John’s Wort — that also increase serotonin levels. But serotonin syndrome has occurred in individuals taking venlafaxine alone. While rare, serotonin toxicity can kill people if they are not treated.

A 2003 case report in The Annals of Pharmacotherapy described a 29-year old woman in Taiwan who developed tremors, shivering, vomiting, diarrhea, an elevated heart rate and other symptoms of serotonin syndrome after receiving “low-dose” venlafaxine therapy of 37.5 mg per day. Doctors treated her with an antipsychotic and a sedative in the emergency department, and her symptoms resolved within two hours.

Rises in Blood Pressure ‘the Most Feared Complication’

Results of controlled trials found dose-related increases in systolic and diastolic blood pressure among patients taking venlafaxine, according to Effexor’s label. The average diastolic increase was 7.2 points among patients taking 375 mg daily — and 13 percent of patients on that dose experienced some sort of sustained elevation in blood pressure. Patients taking 75 mg to 225 mg daily experienced no increase.

Fact

In a 2004 British study, one in 10 patients taking an average dose of 342 mg of venlafaxine daily for depression developed “mildly raised” blood pressure.

Most of the time the elevations in blood pressure associated with Effexor are mild, but some cases have been severe and required immediate treatment.

A 2014 report in the journal Case Reports in Psychiatry described a 23-year-old man who developed nosebleeds and headaches after 10 months of taking 150 mg of venlafaxine daily for depression. He ended up hospitalized in a hypertensive crisis, with a blood pressure reading of 210 over 170. His blood pressure returned to normal when he was taken off the drug.

The authors of the study noted that hypertension is most common in doses exceeding 300 mg per day and is “the most feared complication” associated with the drug’s use.

Increased Chance of Miscarriage and Birth Defects

The use of antidepressants has been linked to an increased risk of miscarriage, according to a study published in the Canadian Medical Association Journal in 2010.

Researchers with the University of Montreal and the CHU Sainte-Justine Mother and Child University Hospital reviewed data collected by the Quebec Pregnancy Registry from 1998 to 2003. The review covered information about 70,000 women between the ages of 15 to 45.

The evaluation included over 5,000 women who had experienced miscarriages up to 20 weeks into the pregnancy and another 51,000 women who did not have miscarriages. Of those women who miscarried, about 5.5 percent had taken antidepressants during their pregnancy.

Overall, the study found a 68 percent increased risk of miscarriage in women who used antidepressants during pregnancy compared to those women who never used the drugs.

Miscarriage Risk

In one study, 33 of 161 women taking venlafaxine suffered a miscarriage. Half of the women taking a dose greater than 150 mg daily miscarried, compared to 19 percent of those taking a smaller dose.

Effexor XR’s label warns that the drug should be used by expectant mothers “only if clearly needed.”

Babies exposed to Effexor and other antidepressants during the third trimester of pregnancy have been born with significant problems including:

• Respiratory distress
• 
  Trouble maintaining body temperature
• 
  Bluish discoloration from poor oxygenation
• 
  Temporary pauses in breathing
• 
  Trouble feeding
• 
  Vomiting
• 
  Low blood sugar levels
• 
  Floppy or rigid muscle tone
• 
  Irritability, jitteriness and constant crying

Such symptoms may represent withdrawal symptoms, serotonin syndrome or other toxic side effects of the drug, according to the drug’s manufacturer.

A 2012 study using data from the National Birth Defects Prevention Study found “statistically significant associations” between venlafaxine use during the first trimester of pregnancy and several serious birth defects including:

• Anencephaly (underdeveloped brain and/or incomplete skull)
• Coarctation (narrowing) of the aorta and other heart defects
• Cleft palate
• Gastroschisis (a hole in the abdominal wall through which intestines or other abdominal organs may protrude)

One explanation for these effects, according to the study’s authors, is that venlafaxine interrupts important “embryologic signaling pathways” that rely on serotonin and norepinephrine. Another possibility is that women who use Effexor have different lifestyles, and therefore, other risk factors.

Lawsuits alleged Effexor’s manufacturer marketed the drug as safe for use during pregnancy despite being aware of an increased chance of birth defects.

Appetite Loss, Anorexia and Weight Loss in Children

In premarketing evaluation of the drug, decreased appetite was observed more frequently in pediatric patients treated with Effexor versus those treated with placebo. In some cases, appetite loss led to anorexia.

During clinical trials, 18 percent to 47 percent of pediatric patients experienced a weight loss of 3.5 percent or more while taking the drug. Over the course of the six-month study, both children and adolescents had height increases that were also less than expected when compared with their peers.

Interstitial Lung Disease and Eosinophilic Pneumonia

Effexor use has been associated with interstitial lung disease and eosinophilic pneumonia in rare instances, according to the drug’s label. Interstitial lung disease is the name for a large group of diseases that can inflame or scar the lungs, resulting in a lack of oxygen. Scarring is permanent.

Eosinophilic pneumonia is a disease in which eosinophils, a type of white blood cell, accumulate in the lungs, and usually in the bloodstream. These cells invade tiny air sacs (alveoli) in the lungs, despite the absence of infection, and make breathing difficult.

Patients who develop shortness of breath, a cough or chest discomfort while taking venlafaxine should contact their physician and should consider ceasing use of the medication, according to the drug’s label.

Withdrawal Symptoms

Another serious Effexor side effect is discontinuation syndrome, which can occur when the medicine is stopped suddenly, the dose is decreased too quickly or a dose is missed. Because venlafaxine has a short half-life of just four hours, withdrawal symptoms can come on rather quickly.

Withdrawal effects may include agitation, insomnia and flu-like symptoms, such as headaches, fatigue and nausea. But a number of patients also described unsettling sensations in the head mimicking electrical discharges. These popping sensations are sometimes referred to as “brain zaps” or “brain shivers.”

To avoid discontinuation syndrome, Effexor should be discontinued gradually, and patients should be monitored for symptoms while weaning off the medication.

According to the drug’s label, patients in clinical trials were successfully tapered by reducing their dosage by 75 mg every week. If severe symptoms develop, the patient’s doctor may temporarily increase the dose and then taper the patient more slowly.

90,000 6 Known Anxiety Drugs That Do Not Cause Weight Gain 90,001

Sedatives that do not cause weight gain may include Effexor, Paxil, and BuSpar. To learn more about these sedative medications, read on. Did You Know? Seeing happy thoughts, our brain gets flooded with positive signals, thereby making us feel better. So, focus on positive thinking to lead a healthy life.
Becomes anxious beyond normal limits for no apparent reason, this is an anxiety disorder.It is estimated that about 40 million people living in the United States suffer from anxiety disorders each year. An effective form of treatment, doctors recommend, involves the use of anxiety medication. These medications relieve tension and give a feeling of relaxation. There are several side effects associated with anxiety medication, and one of them is weight gain. However, not all drugs prescribed for anxiety disorders cause significant weight gain.Some of them are listed below:

— Generalized Anxiety Disorder: Causes, Symptoms and Treatment

Venlafaxine (Effexor)
This is an antidepressant commonly prescribed to treat anxiety disorders. Effexor tries to restore chemical balance in the brain, which helps relieve anxiety disorders. With Effexor, gaining weight is very rare and the percentage of people who reported weight gain is very less (about 1%). On the contrary, the most common side effect associated with Effexor is weight loss.In the case of weight gain observed with Effexor, a simple way to combat this rarely problem is to reduce your calorie intake due to the presence of a fiber diet. Eat plenty of fresh fruits and vegetables and prefer lean meats and fish over saturated fats.

— Start a new chapter by reading these tips on how to stop worrying

Paroxetine (Paxil)
Paxil does not generally cause weight gain and has been approved for the treatment of various types of anxiety disorders, including panic disorder.Gaining weight with Paroxetine is very rare and has been proven in clinical studies. Extensive research has been done before this drug was approved for anxiety. In a study by experts, over a thousand people suffering from this mental illness were given Paxil. It was found that only 2-3% of people were noticed gaining weight.

Buspirone (BuSpar)
Before any drug is legalized for any disease, clinical trials are conducted for possible side effects.It was noted that weight gain as a side effect was seen in less than 1% of patients. Thus, we can definitely say that gaining weight due to BuSpar is a rare occurrence.

Clonazepam (Klonopin)
This is a prescription medication that belongs to a class of medicines called benzodiazepines. Usually recommended for people with panic disorder problems, weight change is not an annoying side effect. Again, studies show the same statistics as weight gain reported in about 1 in 1000 people.

Ativan (Lorazepam)
Although there may be several side effects associated with the use of Ativan, it is surprising that studies have not found any weight gain among people who took this drug. So, it is very unlikely that Ativan prescribed for anxiety disorders will result in weight gain. However, this anxiety medication provides short-term relief.

Antidepressants
Antidepressants are often used to treat generalized anxiety disorder (GAD).There are several different types of antidepressants, but one that has been shown to be effective for improving the symptoms of reptile without causing any side effects such as weight gain selective serotonin reuptake inhibitors (SSRIs). Cioses affect the neurochemical serotonin, which is involved in regulating mood. This chemical found in the brain helps neurons communicate with each other. Serotonin deficiency has been linked to anxiety disorders, panic attacks, and low self-esteem.Cioses boost mood by increasing serotonin levels in the brain. It does this by inhibiting the reabsorption (re-absorption) of serotonin in the brain. Some of the Cioses that have been found to be helpful in raising your mood without adding pounds to your existing weight are listed below:
Fluvoxamine (Fevarin)
Citalopram (Cipramil)
Fluoxetine (Prozac)
Anxiety drugs that do not cause significant weight gain is Escitalopram (Lexapro) and Sertraline (Zoloft).Although these drugs can provide significant relief from anxiety symptoms, other side effects such as nausea and weakness have been experienced by the sufferer. Therefore, it would be wise to consult your doctor before using these anxiety medications.

People have an annoying habit of remembering things they shouldn’t. ~ Christopher Paolini
The point to note here is that simply taking sedatives will not cure mental illness unless you change your thought process.Remember, our body reacts to the way we think. Therefore, try to be in a positive mood and avoid thoughts that are a source of stress and anxiety. Meditate, listen to popular music, play an instrument like a guitar, or do anything that keeps you from feeling anxious. In fact, when you tune your mind to think positively, you will not require any medication and the issue of weight will not arise.
Disclaimer: The information provided in this article is for the information of the reader only.It is not intended to be a substitute for consultation with an expert doctor.

Comments

90,000 The most dangerous antidepressants during pregnancy are named // Look

These include primarily venlafaxine and amitriptyline. Other antidepressants, however, are also undesirable.

“Depression must be treated, and during pregnancy too,” says Anik Bérard, scientific director of the Department of Drugs, Pregnancy and Breastfeeding at the University of Montreal.The only question is the selection of safe methods of treatment. Meanwhile, a new study has shown that certain antidepressants significantly increase the risk of gestational diabetes (HD).
Gestational diabetes is an abnormal increase in blood glucose (sugar) levels that first occurs during pregnancy. For the study, Anik Bérard and her team looked at medical records of all pregnancies in Quebec between 1998 and 2015. The researchers highlighted data from nearly 21,000 women with gestational diabetes, comparing them to more than 209,000 women without the disease.Just over 4% of women with gestational diabetes were taking antidepressants. Among them were: fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil) and sertraline (Zoloft), belonging to the group of selective serotonin reuptake inhibitors (SSRIs). Also, drugs from other groups were used: venlafaxine (Effexor) of the SNRI group and amitriptyline (Endep), a representative of cyclic antidepressants.
The use of any of these drugs increased the risk of developing gestational diabetes by 19% compared with no use.According to experts, the most dangerous were Effexor, which increased the risk of HD by 27%, and Endep, which increased the risk of HD by 52%. The risk was greater the longer the medication was taken.
Researchers speculate that these drugs affect glucose metabolism. Also, one of the side effects of antidepressants is weight gain, a known risk factor for diabetes.
Therefore, despite the fact that it is necessary for the expectant mother to treat depression, scientists advise choosing non-drug methods for this: psychotherapy, exercise, etc.
90,000 What psychoactive drugs lead to weight loss or gain. | Psychologram.ru

Weight gain associated with psychoactive drugs is one of the side effects that most worry patients. At the end of the day, this is a delicate issue that needs special attention. Weight fluctuations vary from patient to patient and depend on the type of treatment, so it is difficult to define criteria that can be generalized.

Many drugs used to treat anxiety, depression, borderline personality disorder, schizophrenia, and epilepsy can lead to weight gain or weight loss.

Research shows that patients are more likely to withhold treatments that cause weight gain. In these cases, it is important to help the patient avoid weight gain through a healthy diet and adequate exercise.

Occasionally, a healthcare professional may change the dose or dose schedule of treatment to prevent weight gain and unwanted conditions. The side effects of weight gain can be serious, so it is important to address the patient’s concerns.

Weight loss is seen as a side effect of many drugs. Although excessive weight loss is also a problem, patients tend to accept it more as a side effect.

Weight gain and antidepressants

People often associate antidepressants with weight gain, and they are not wrong. Weight gain is one of the possible side effects that can be seen with most antidepressants. However, some medications used to treat depression are more likely to cause it than others.For example:

• Certain tricyclic antidepressants (TCAs) such as amitriptyline, imipramine, and doxepin.
• Certain MAOIs (monoamine oxidase inhibitors) such as phenelzine.
• Certain SSRIs such as paroxetine (selective serotonin reuptake inhibitor).
• Mirtazapine is an atypical antidepressant.

It is important to keep in mind that antidepressants are not always the direct cause of weight gain. Many factors can come into play and contribute to the problem during any depression treatment.

In some cases, depression itself causes weight gain because the patient is inactive, immobile, or has problems with emotional eating. In other cases, depression leads to weight loss. Treatment with antidepressants improves the patient’s mood, which increases appetite and leads to weight gain.

Thus, it is clear that some antidepressants cause weight gain as a side effect. However, it is important to know that the drug is not always directly responsible for weight gain.Check with your doctor before making any decisions about your medications.

Weight gain and antipsychotics

For patients taking antipsychotics, weight gain and metabolic changes are the most worrisome side effects. This is important because, as we mentioned above, patients are less likely to use their medications as directed if they think they will gain weight.

Classic antipsychotic drugs cause greater weight gain.Other antipsychotics, such as clozapine, olanzapine, quetiapine, risperidone, and ziprasidone, can also cause significant weight gain. Medicines used to treat bipolar disorder, such as lithium, carbamazepine, and valproic acid, also tend to cause weight gain.

Schizophrenia is also directly related to metabolic changes. For example, patients with psychotic disorders are more likely to be obese.

Whether it is the result of discomfort or the medication you use to treat it, you can fight weight gain through lifestyle changes.Exercise and diet are the most important and effective. Sometimes, however, the patient will need other medications to help him lose weight.

Weight gain is a side effect of treatment with certain psychoactive drugs. However, patients can often reduce or completely prevent the problem with lifestyle changes and a trained healthcare professional. If you have weight problems, do not hesitate to talk to your doctor.

Especially for disorders that are treated with psychoactive drugs, it is imperative that you continue to take the medication to prevent recurrence.Changing your treatment is always a better option than stopping your treatment altogether.

You can always get a free consultation with a psychologist by filling out the form below.

Does protriptyline cause weight gain?

11 Related question

The Vicks Waterless Vaporizer uses heat to activate the soothing Vicks menthol vapors in the aroma pad and release them into the air.A soft night light helps you find a waterless vaporizer in a dark room. Three settings to control the amount of soothing vapors released into the air. Uses Vicks VapoPads®.
Click to see full answer

Then how to use Vicks waterless vaporizer? Instructions:
Unwind the cord completely. Open the lid of the Vicks waterless vaporizer. Place one scent pad on the vents. Lower the cover and push firmly to lock it in place.Turn on the device using the switch. Adjust to desired value for desired odor release. Also, does the Vicks vaporizer automatically shut off? Vicks Warm Steam Evaporator with Steam Guard for maximum performance and reliability. Steam helps temporarily relieve coughs and nasal congestion. the evaporator will automatically shut off when the water reaches the minimum level.
How does the Vicks plugin work here?
How it works: The soothing vaporizer is inserted into the waterless vaporizer and works by heating to activate the soothing menthol vapors in Vicky’s vapors and release them into the air.Guiding slots make it easy to insert and remove the scent pads. Soft glowing night light. Just plug in your device and enjoy soothing comfort for up to 8 hours.
Can I use VapoPads for a baby?
When it comes to keeping your child healthy, you should never risk taking medications that are not 100% safe. If your child is under 2 years old, you should never apply Vix to his chest, nose, feet or anywhere else.Use them to release the menthol scent to soothe and relieve your child’s nasal congestion.

Replace the steam block and connect the evaporator. It should be steamed for 5 minutes. If it doesn’t or produces only a small amount of steam, add a pinch or two more as needed, up to ½ teaspoon.
Click to see full answer

Also know how long can I leave the Vicks on? Customer Service Vicks Vaporizers & Thermometers in 1 Hour You can use the device continuously for as many days as you need while you are sick.Just make sure you unplug it, empty and rinse it between night uses (if you use it at night) and clean regularly according to the instructions for use.
Also, is the Vicks Warm Steam Vaporizer safe for babies? The study reports that the combination of VapoRub camphor, menthol and eucalyptus oils may relieve symptoms and improve sleep in children with upper respiratory tract infections. Unfortunately, this only applies to children over 2 years of age.Vicks is not safe for babies.
Similarly, the question is, does the Vicks Warm vaporizer emit Steam Warm?
When I add Vicks Vapo Steam liquid, it makes a gurgling sound and splashes water all over the place. You shouldn’t add vetch to water, just salt, but less than a pinch and not always. Usually, the water only splashes for a few minutes, and then the steam comes out many times.
Can the humidifier be left on overnight?
The experts said it is safe to leave the humidifier on overnight.But it does apply if you know how your home and body react to moisture. As the air gets drier and the temperature drops, you can use a humidifier that can lower the cold temperature. ailments.

Smoke damage can occur even if your vehicle is involved in a severe fire, such as a forest fire. All of these can affect the safety of your vehicle.Minimal fire damage usually occurs from lit cigarettes and other sources of ignition. Even a small fire is likely to leave behind smoke, which can lead to stains and odors.
Click to see full answer

So, can smoke damage car paint? Smoke and ash from distant fires can damage your car! ! Bringing an ash-covered car outside on wet nights or foggy mornings can lead to chemical etching and, in some cases, cause serious damage to the painted surfaces of the car.Our car care professionals know how to remove ash without damaging the paint.
Also, does smoke ever come out of the car? Smoke can leave a persistent and undesirable odor in the car. Smoke is also a smell that is difficult to get rid of forever. After the odor-causing debris has been removed, you must clean any fabric seats or leather surfaces in the car.
With this in mind, is it allowed to smoke in the car?
One of the last safe havens for smokers is the car.However, research shows that smoking indoors in a car seriously contaminates the interior with nicotine and other fumes. This nicotine contamination is a third party exposure.
What is smoke in a car?
Smoke damage instantly destroys the value of the vehicle. Visible marks and odors left behind indicate a fire that most potential car buyers would consider a serious hazard, regardless of whether the vehicle is in good order.

The tobacco plant itself contains harmful chemicals from the outset, including the highly addictive nicotine. In addition to nicotine, toxic chemicals such as cadmium and lead are often found in the soil where tobacco plants grow, and fertilizers often contain nitrates. You inhale these chemicals when you smoke.
Click to see full answer

Also, is tobacco good for the soil? “The mixture is really important.We are very careful about mixing the right amount of carbon and nitrogen so that it quickly disintegrates, odorless and becomes the best natural fertilizer that can be. ” Tobacco is a great source of nitrogen, so it’s good for the composting process.
Is tobacco water good for plants? Submerge a cup of loose tobacco in a gallon of water, let sit overnight, strain and spray. Caterpillars, aphids and a variety of insects prone to eating plants will soon abandon your vegetables and flowers in search of less unpleasant food.It also asks the question, is cigarette smoke harmful to plants?
Plants can be affected in both positive and negative ways by smoke. Smoke from the combustion of any material means that there is an increased level of carbon dioxide in a limited area. These effects are harmful to plants. Cigarette smoke and some other types of smoke also contain tar, which can clog the pores of the stomata.
Does tobacco have any beneficial effects?
Hence, nicotine has been shown to have a positive effect on certain diseases.The positive effects of nicotine on cognitive function suggest that nicotinic receptors may contribute to normal cognitive functioning and that nicotine may help Alzheimer’s patients. therapy.

Sleep, energy, or appetite may improve slightly during the first 1 to 2 weeks. Improvement in these physical symptoms can be an important early signal that a drug is working.It may take up to 6-8 weeks to fully improve depressed mood and lack of interest in exercising.
Click to see full answer Also asked how long does it take for venlafaxine to relieve anxiety?
It may take four weeks or more to get the full effect. For anxiety, antidepressants such as venlafaxine may take a little longer to work. In some people, anxiety increases briefly at the beginning of treatment, but decreases with continued treatment.Also, is Effexor helpful for anxiety? Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It can also reduce fear, anxiety, unwanted thoughts, and panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI).
You also need to know how long does it take to feel the Effexor XR effect?
To reduce the risk of side effects, your doctor may start with a low dosage and gradually increase it as tolerance develops (it will be between 37.5 mg and 300 mg).It can take several weeks for the benefits of this medication to be felt, so be sure to take it around the same time every day for best results.
How long does venlafaxine take into your body?
You may see improvement in your symptoms after a week, although it usually takes 4 to 6 weeks before you feel all the benefits. This is because it takes about a week for venlafaxine levels to reach in your body, and then a few more weeks for your body to adapt and get used to it.

Venlafaxine has a half-life of 3 to 7 hours, and its active metabolite, desvenlafaxine, has a half-life of 9 to 13 hours. Higher rates of withdrawal symptoms are associated with higher doses of venlafaxine and longer duration of treatment.
Click to see full answer

With this in mind, how long does venlafaxine stay in your body? You must first learn about the half-life of a drug, which is the time it takes to reduce the plasma concentration by half.its original cost. The half-life of Effexor is approximately 5 hours (+/- 2 hours), which is extremely short compared to other antidepressants.
Also, what is the best time of day to take venlafaxine? The tablet is usually taken two or three times a day with meals. Extended-release capsules are usually taken once a day in the morning or evening with a meal. Take venlafaxine at about the same time every day.
With this in mind, can venlafaxine be taken for life?
Most doctors recommend taking antidepressants for 6 months to 1 year after you stop feeling depressed.Stopping before this time can bring depression back. Your doctor will likely recommend that you gradually taper your dose over several weeks – or longer if you have been taking venlafaxine for a long time.
Is venlafaxine fatiguing?
A: The side effects of Effexor (venlafaxine) are similar to those of other antidepressants. Common Effexor side effects include drowsiness, weakness, dizziness, anxiety, trouble sleeping, and nervousness. Dry mouth is another common side effect.

Since there is currently no research available on the effects of vaping with essential oils, avoid vaping any essential oil. your best choice. Even essential oils that are generally considered safe to inhale can change and become toxic when heated for vaping.
Click to see full answer

Similarly, you might ask which oils are safe for vaping? We can divide vaping oils into two broad categories: Essential oils (peppermint, rosemary, chamomile, lavender, etc.)) hemp oils (CBD oils, THC oils, hemp oil) Vaping of THC and CBD oils is:
More powerful. Cleaner. More discreet. Faster. Likewise, is vitamin E acetate in essential oils? Vitamin E Acetate is a virtually odorless emollient for virtually oily skin. It has a viscous texture with slow absorption into the skin. It has no antioxidant properties for essential oils or perfume compounds.
Also, are essential oils bad for your lungs?
“In fact, inhaling oil particles can actually cause airway inflammation and asthma symptoms,” she says.“Strong odors from essential oils can contain volatile organic compounds or VOCs. VOCs are chemical gases that degrade air quality and can irritate the lungs. ”
Can I vape with just water?
So, the answer to the question ‘can water be poured into a vape pen?’ yes, you can. Not only is this not the feeling of comfort that you are accustomed to with normal vaping, but it can also be harmful to your mouth. When you vaporize water, it actually turns into very hot water vapor.

Menthol has a cooling and analgesic (or pain relieving) effect. It also reduces the cough reflex and can soothe the dry throat that many smokers experience. As a result, menthol smokers can inhale more deeply, retain smoke in their lungs longer, and be more exposed to hazardous chemicals in cigarette smoke.
Click to see full answer

People also ask if menthol crystallizes in your lungs? While we cannot calm your mind about cigarette smoking, we can at least calm you down that the menthol contained in menthol cigarettes does not crystallize in your lungs or otherwise harm your health.Menthol makes the skin cooler by stimulating the nerve endings that detect cold.
Also know what menthol cigarettes do to your lungs? Menthol has a cooling and analgesic (or pain relieving) effect. It also reduces the cough reflex and can soothe the dry throat that many smokers experience. As a result, menthol smokers can inhale more deeply, retain smoke in their lungs longer, and be more exposed to hazardous chemicals in cigarette smoke.Also, is inhaling menthol bad for you?
There are calcium channels in the cell walls of our body, so we can observe systemic toxicity after ingesting or inhaling concentrated amounts of menthol. Serious consequences include convulsions, coma, and death. Menthol may irritate the eyes and skin.
What are the side effects of menthol?
Signs of an allergic reaction, such as a rash; hives; itching; red, swollen, blistered, or scaly skin with or without fever; wheezing; tightness in the chest or throat; difficulty breathing, swallowing, or speaking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.Very severe skin irritation.

While we cannot reassure you by smoking cigarettes, we can at least assure you that the menthol in menthol cigarettes does not crystallize in your lungs or otherwise harm your health. Menthol makes the skin feel colder by stimulating the nerve endings that detect cold.
Click to see full answer

People also ask, what do menthol cigarettes do for your lungs? Menthol cigarettes are flavored with menthol, which triggers cold-sensitive nerves in the skin.Menthol has a cooling and analgesic (or pain relieving) effect. As a result, menthol smokers can inhale more deeply, retain smoke in their lungs longer, and be more exposed to hazardous chemicals in cigarette smoke.
Second, is menthol bad for the lungs? “Menthol cigarettes are just as dangerous as non-menthol cigarettes, and cigarettes are the # 1 cause of heart disease, lung cancer, chronic obstructive pulmonary disease (COPD) and other diseases.”Whether you smoke menthol or non-menthol, “set a date after which you become a former smoker,” he says.
People ask if menthol cigarettes really crystallize your lungs?
Menthol in cigarettes relieves pain in the lungs, the study said. New research shows that menthol, when combined with nicotine in cigarettes, suppresses the body’s ability to signal irritation from smoking.
Why are menthol cigarettes banned?
It has been proposed that menthol cigarettes, which are more addictive but not healthier, should be banned, in part on the grounds that marketing a more addictive product is a social injustice.

The racial marketing strategies of American tobacco companies changed in the 1950s. It has been suggested that menthol cigarettes, which are more addictive but not healthier, should be banned, in part on the grounds that race-focused marketing of a more addictive product is a social injustice.
Click to see full answer

Also know if you can buy menthol cigarettes? Menthol cigarettes and rollies will be banned later this year in an effort to quit smoking among young people.Smokers will no longer be able to buy cigarettes and tobacco for smoking with any “characteristic flavors” after May 20. And Brexit is unlikely to affect the Smoking and Health Action ban. said the charity.
Why are flavored cigarettes banned? The Household Smoking Prevention and Tobacco Control Act passed by the US Congress in October 2009 bans cigarettes with flavors other than menthol or tobacco. At the same time, the ban was associated with a 6.1 percent reduction in the overall consumption of tobacco products by young people.Then will menthol cigarettes be banned in the US?
Anti-smoking groups have welcomed the ban, which immediately restricts the sale and consumption of flavored vaping products, and does the same for menthol cigarettes from June 1, 2020. The restriction applies to menthol cigarettes and flavored e-cigarettes, cigars, pipe tobacco and chewing tobacco.
How harmful are menthol cigarettes?
The menthol in cigarettes does not make smoking any safer than regular non-menthol cigarettes.Smoking menthol cigarettes is harmful to health, including increasing the risk of cancer, heart disease and lung disease.

SSRI administration Interactive drug All monoamine oxidase inhibitors (MAOIs), including moclobemide Fluoxetine and paroxetine (possibly citalopram)