Enbrel reviews. Enbrel for Rheumatoid Arthritis: Patient Reviews on Effectiveness and Side Effects

16.07.202302.07.2023 by alexxlab

How effective is Enbrel for treating rheumatoid arthritis. What are the most common side effects reported by patients. How long does it take for Enbrel to start working. What should patients know before starting Enbrel treatment.

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Understanding Enbrel: Mechanism of Action and Approved Uses

Enbrel (etanercept) is a biologic medication used to treat several autoimmune conditions, including rheumatoid arthritis (RA), psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. As a tumor necrosis factor (TNF) inhibitor, Enbrel works by targeting and reducing inflammation in the body.

How does Enbrel work to treat rheumatoid arthritis. Enbrel binds to and blocks the action of TNF, a protein involved in triggering inflammation. By inhibiting TNF, Enbrel helps reduce joint pain, swelling, and damage associated with RA and other inflammatory conditions.

Patient-Reported Effectiveness of Enbrel for Rheumatoid Arthritis

Patient reviews on the effectiveness of Enbrel for treating rheumatoid arthritis are mixed. While some users report significant improvement in their symptoms, others experienced limited or no benefit.

One patient shared: “This medication has worked well with me… I’m satisfied with the results on my joint pain.” However, another user stated: “The cost was extremely high even with insurance and the results were poor.”

Is Enbrel effective for all RA patients. The varied responses suggest that Enbrel’s effectiveness can differ from person to person. Factors such as disease severity, duration, and individual physiology may influence how well a patient responds to the treatment.

Timeframe for Experiencing Benefits

A common question among patients is how long it takes for Enbrel to start working. One user reported: “I have been on Enbrel for 15 weeks (almost 4 months now) to treat my RA… I am still having a lot of pain in the joints in my hands and feet, as well as my jaw.”

How long should patients wait to see results from Enbrel. While some patients may experience improvement within a few weeks, it can take up to 3-6 months for the full benefits of Enbrel to become apparent. Patients are advised to continue treatment as prescribed and communicate regularly with their healthcare provider about their progress.

Reported Side Effects and Safety Concerns

As with any medication, Enbrel comes with potential side effects. Patient reviews highlight a range of experiences, from mild discomfort to severe adverse reactions.

Injection site reactions (redness, itching)
Fatigue
Increased risk of infections
Potential long-term health risks

One user noted: “The injection site is always red and itchy but all in all I’m satisfied with the results on my joint pain.” However, more severe side effects were also reported, with one reviewer stating: “This medication killed my mother. She was one that believed in her doctor and did not so much research on prescribed medications. Her doctor also did not do much research about adverse effects with her other medications. 2 weeks after starting this medication she had every side effect. 2 weeks later she was dead.”

Are there serious long-term risks associated with Enbrel use. Some patients and their families have reported concerns about potential long-term health risks, including an increased risk of certain cancers. One user shared: “My husband took Enbrel for 3 years… his lungs are full of small malignant tumors, his lungs are FULL of individual tumors, both lungs…from Enbrel.”

It’s crucial to note that while these anecdotal reports are concerning, they do not necessarily represent the typical experience of most Enbrel users. Patients should discuss the potential risks and benefits of Enbrel with their healthcare provider before starting treatment.

Ease of Use and Administration

Enbrel is typically self-administered via subcutaneous injection. Patient reviews indicate varying experiences with the injection process.

How user-friendly is the Enbrel injection system. Some patients find the process straightforward, while others report challenges. One user commented: “The needle needs to be worked on it is actually very painful. I was on Humira and their needle didn’t hurt at all.”

For patients who struggle with self-injection, alternative administration options or additional training from healthcare providers may be beneficial.

Cost and Insurance Coverage Considerations

The high cost of Enbrel is a significant concern for many patients, even those with insurance coverage. One reviewer noted: “The cost was extremely high even with insurance.”

How can patients manage the cost of Enbrel treatment. Some options to consider include:

Discussing financial assistance programs with healthcare providers
Exploring patient assistance programs offered by the manufacturer
Investigating insurance coverage options and appeals processes
Considering biosimilar alternatives if available and approved by the prescribing physician

Enbrel Compared to Other RA Treatments

Patient reviews often include comparisons between Enbrel and other rheumatoid arthritis treatments. These comparisons can provide valuable insights for patients considering their treatment options.

How does Enbrel compare to other biologic medications for RA. One patient shared their experience transitioning between treatments: “For about 3 months it worked perfectly and I was able to exercise again until it started to wear off before the next injection and eventually stopped working altogether. Blood test revealed I had developed antibodies to the Enbrel, making it useless as a treatment… Getting switched to a combo of Humira and low dosage Methotrexate soon.”

This experience highlights the importance of monitoring treatment effectiveness and being open to adjusting medication regimens as needed. It also underscores the fact that patients may respond differently to various biologic medications.

Combination Therapies

Some patients report using Enbrel in combination with other medications to enhance its effectiveness. For example, the combination of Enbrel with methotrexate is a common approach in rheumatoid arthritis treatment.

Is combining Enbrel with other medications more effective than using it alone. While combination therapies can be more effective for some patients, they may also carry additional risks. Patients should work closely with their rheumatologists to determine the most appropriate treatment approach for their individual cases.

Managing Expectations and Monitoring Progress

Patient reviews highlight the importance of managing expectations when starting Enbrel treatment. While some users experience rapid improvement, others may need to wait longer to see benefits or may not respond to the medication at all.

How can patients effectively monitor their progress on Enbrel? Consider the following strategies:

Keep a symptom diary to track changes in pain, stiffness, and overall function
Attend regular follow-up appointments with your rheumatologist
Undergo recommended blood tests and imaging studies to assess disease activity and potential side effects
Communicate openly with your healthcare provider about any concerns or changes in your condition

Is it normal to experience fluctuations in symptoms while on Enbrel? Some patients report variations in their symptoms over time, even while on consistent treatment. One user shared: “For about 3 months it worked perfectly and I was able to exercise again until it started to wear off before the next injection and eventually stopped working altogether.”

These fluctuations can be due to various factors, including the natural course of the disease, stress, concurrent infections, or the development of antibodies to the medication. Patients experiencing persistent changes in their symptoms should consult their healthcare provider to determine if adjustments to their treatment plan are necessary.

Patient Education and Informed Decision-Making

The importance of patient education and informed decision-making is a recurring theme in many Enbrel reviews. Patients who feel well-informed about their treatment options and potential risks tend to report higher satisfaction with their care.

How can patients become better informed about Enbrel and their treatment options? Consider these approaches:

Research reputable medical sources and patient advocacy organizations
Prepare questions for your healthcare provider before appointments
Seek second opinions when appropriate
Join support groups or online communities to learn from other patients’ experiences
Stay up-to-date on the latest research and treatment developments in rheumatoid arthritis

Is it important to discuss all medications and supplements with your doctor before starting Enbrel? Absolutely. One reviewer cautioned: “Her doctor also did not do much research about adverse effects with her other medications.” This highlights the critical importance of comprehensive medication reviews to prevent potentially dangerous drug interactions.

Recognizing and Reporting Side Effects

Patient reviews emphasize the importance of being vigilant about potential side effects and reporting them promptly to healthcare providers. This includes both immediate reactions and any new or worsening symptoms that develop over time.

What should patients do if they experience side effects while taking Enbrel? Follow these steps:

Document the nature, severity, and timing of the side effect
Contact your healthcare provider immediately for severe or concerning symptoms
Report the side effect to the appropriate regulatory agency (e.g., FDA in the United States)
Discuss with your doctor whether the benefits of continuing Enbrel outweigh the risks

By actively participating in their care and maintaining open communication with their healthcare team, patients can help ensure they receive the most appropriate and effective treatment for their rheumatoid arthritis.

Quality of Life Improvements and Treatment Goals

While managing symptoms is a primary goal of Enbrel treatment, many patient reviews also touch on broader quality of life improvements. For some, the ability to engage in daily activities and maintain independence is a crucial measure of treatment success.

How does Enbrel impact patients’ overall quality of life? Positive reviews often mention improvements such as:

Increased mobility and joint function
Ability to return to work or hobbies
Reduced fatigue and improved energy levels
Better sleep quality
Enhanced emotional well-being due to better symptom control

One patient shared: “It was worth it during the time it did work, some moderate side effects but nothing intolerable like head or stomach ache. Still worth it.” This comment highlights the personal nature of weighing the benefits against the side effects when evaluating treatment success.

Should patients set specific treatment goals with their rheumatologists? Absolutely. Setting clear, measurable goals can help patients and their healthcare providers assess the effectiveness of Enbrel and make informed decisions about continuing or modifying treatment. These goals might include specific improvements in joint function, reduction in pain levels, or the ability to perform certain activities.

Long-term Disease Management

Patient reviews often reflect the challenges of managing rheumatoid arthritis as a chronic condition. While Enbrel can be effective in controlling symptoms and slowing disease progression, it is not a cure, and many patients must continue treatment indefinitely.

How can patients effectively manage their RA over the long term while on Enbrel? Consider these strategies:

Adhere to the prescribed treatment regimen
Incorporate lifestyle modifications such as regular exercise and a healthy diet
Manage stress through relaxation techniques or counseling
Stay informed about new developments in RA treatment
Build a strong support network of family, friends, and healthcare providers

Is it possible to reduce or discontinue Enbrel treatment over time? Some patients report being able to reduce their medication or even discontinue use after achieving prolonged remission. One reviewer noted: “My husband took Enbrel for 3 years he has been off of it, really hasn’t needed it in about a year.” However, decisions about reducing or stopping treatment should always be made in consultation with a rheumatologist, as premature discontinuation can lead to disease flares.

The Role of Patient Advocacy and Support

Many Enbrel reviews highlight the importance of patient advocacy and support in navigating the challenges of rheumatoid arthritis treatment. Connecting with others who have similar experiences can provide valuable insights, emotional support, and practical tips for managing the condition.

How can patient support groups benefit those using Enbrel? Support groups can offer:

A platform to share experiences and coping strategies
Information about the latest research and treatment options
Emotional support and understanding from peers
Practical advice for managing daily life with RA
Resources for patient advocacy and navigating healthcare systems

Where can patients find reliable support groups and resources? Consider exploring options such as:

Local hospital or clinic-based support groups
National organizations like the Arthritis Foundation
Online forums and social media groups dedicated to RA and Enbrel users
Patient advocacy organizations focused on autoimmune diseases

Is it beneficial to involve family members in the treatment journey? Many patients find that educating their loved ones about RA and involving them in their care can lead to better support and understanding. This can be particularly important when dealing with the invisible aspects of the disease, such as fatigue and pain, which may not be apparent to others.

Navigating Work and Social Life

Patient reviews often touch on the challenges of managing work and social commitments while dealing with RA and Enbrel treatment. Some users report significant improvements in their ability to engage in daily activities, while others continue to struggle with balancing their health needs and other responsibilities.

How can patients effectively communicate their needs in work and social settings? Consider these approaches:

Be open about your condition with employers and colleagues as appropriate
Explore workplace accommodations that can help you perform your job effectively
Set realistic expectations with friends and family about your capabilities and limitations
Practice self-advocacy and learn to say no when necessary to protect your health
Educate others about RA to foster understanding and support

By sharing their experiences and strategies, patients using Enbrel can help create a more supportive and informed community for those living with rheumatoid arthritis.

Effectiveness, Ease of Use, and Satisfaction

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Most voted positive review

39 People found this comment helpful

my husband took enbrel for 3 years he has been off of it, really hasn’t needed it in about a year, last week he had a chest e-ray for a surgery needed, his lungs are full of small malinant tumors, his lungs are FULL of individual tumors, both lungs…from Enbrel, don’t be foolish and take this drug, yes it makes you feel better at the time but long term this drug is not worth it, we have a hell of…

Most voted negative review

4 People found this comment helpful

The cost was extremely high even with insurance and the results were poor.

Shared reviews and ratings

SORT BY Condition: Rheumatoid Arthritis

Overall rating 1. 0

EffectivenessEase of UseSatisfaction

This medication killed my mother. She was one that believed in her doctor and did not so much research on prescribed medications. Her doctor also did not do much research about adverse effects with her other medications. 2 weeks after starting this medication she had every side effect. 2 weeks later she was dead. She went in only because 1 finger was giving her problems with rheumatoid arthritis. This medication cost my mother her life.

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Fill 3Created with Sketch. Condition: Other

Overall rating 2.7

EffectivenessEase of UseSatisfaction

Makes me tired. Wish there were better choices.

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Fill 3Created with Sketch. Condition: Rheumatic Disease causing Pain & Stiffness in Backbone

Overall rating 2.3

EffectivenessEase of UseSatisfaction 1

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 4.7

EffectivenessEase of UseSatisfaction

This medication has worked well with me, but the needle needs to be worked on it is actually very painful I was on Humira and their needle didn’t hurt at all.. The injection site is always red and itchy but all in all I’m satisfied with the results on my joint pain.

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 2. 3

EffectivenessEase of UseSatisfaction

MY MOTHER 67 YEAR OLD. BEGAN ON EARLY 2019 on this treatment a year later later ANAL CANCER. we went into the cancer experience with her, quimios, radiotherapy. it was HELL. this medication is the worse. STOP TAKING IT

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Fill 3Created with Sketch. Condition: Polyarticular Juvenile Idiopathic Arthritis

Overall rating 3.7

EffectivenessEase of UseSatisfaction

Was diagnosed with Polyarticular Juvenile Idiopathic Arthritis at the age of 16. Within about 8 months the slight lower back aches and an ache in left ankle had gotton worse, spread to my other ankle, my knees, jaw, wrists, and all fingers. Doc confirmed diagnoses with MRI of the lower spine to find years worth of arthritis damage in the SI joints and immediately prescribed Enbrel. For about 3 months it worked perfectly and I was able to exercise again until it started to wear off before the next injection and eventually stopped working altogether. Blood test revealed I had developed antibodies to the Enbrel, making it useless as a treatment. It was worth it during the time it did work, some moderate side effects but nothing intolerable like head or stomach ache. Still worth it. Bummer that my body had to reject the medication like that. Getting switched to a combo of Humira and low dosage Methotrexate soon.Read More Read Less

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 2.3

EffectivenessEase of UseSatisfaction

I am wondering about others thoughts on the length of time needed for enbrel to start working. I have been on Enbrel for 15 weeks (almost 4 months now) to treat my RA. I am only 28 years old, and was previously on Plaquenil and Prednisone. Neither of which worked for me. I am still having a lot of pain in the joints in my hands and feet , as well as my jaw. About 8 weeks ago, I started having sever back/spine pain. And xray showed that the vertebrae in my neck and rather close together, indicating arthritis. My rheumotologist has said, on more than one occasion that back pain is NOT common in people in RA which I DO NOT believe. Is anyone else with RA experienceing this kind of stabbing/burning/numb pain in their back/neck and spine? Also- For those taking Enbrel, how long do you think it took before you started to see relief? Sincerely- A frustrated Enbrel User. Read More Read Less

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I started Ebrel in January. It has worked great for me. However, I have a question for people that takes this, do you get flare-ups every now and then?

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Fill 3Created with Sketch. Condition: Psoriasis associated with Arthritis

Overall rating 4.7

EffectivenessEase of UseSatisfaction

On Enbrel for 6 years years. Topicals did almost nothing for it. The joint pain was miserable. I went on methotrexate for about a year, which helped get rid of the pain and some of the plaque psoriasis. I have been on Enbrel for about 6 years now and generally the joint pain is gone. I saw the posts on the potentials and hope the cancers and other bad things don’t surface. I don’t know what to take that will work but plan to talk to my doctor and see if he has other offers. The cost is extremely high and once the ACA prevented people on Medicare from getting drug company assistance the cost was full retail ( $41k ) and way beyond my ability to pay. Fortunately I found a drug insurance that cost me only $6500 per year. Not sure after reading the warning posts what to do.Read More Read Less

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Fill 3Created with Sketch. Condition: Moderate to Severe Plaque Psoriasis

Overall rating 2.3

EffectivenessEase of UseSatisfaction

At the start Enbrel did a nice job of reducing plaque and, as I cannot take NSAIDs, controlling the arthritis. After a year or so its effectiveness gradually reduced to where I discussed a change with my dermatologist. The weekly shots were another negative though the auto inject system was pretty good. I switched to Cosentyx which, after 15 months, continues to be effective. Sure like the monthly injections, even if there are two of them.

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I have been taking Enbrel a little over 12 years and have loved it! When I was diagnosed with rheumatoid arthritis at age 19, I could hardly eat because of jaw pain and could barely walk without crutches. Since I have been on Enbrel,I am able to do anything I want with no pain at all. Every once in awhile I’ll get a stiff knee but it’s very rare and normally only if it’s really humid. The past 2 months I have developed Urticaria. My rheumatologist is concerned the Enbrel has triggered a reaction and has instructed me not to take it anymore. I am concerned because the reason we started the injections was because nothing else seemed to work for me. The injections are quick and easy and are no worse than any other injection. I love my Enbrel and don’t want to give it up. All blood work has been very normal with no problems, I am very active and so far very healthy. A little concerned about all of the cancer comments but I am hopeful that my doctor’s will keep up with blood work in case anything we’re to come up. Read More Read Less

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 3.7

EffectivenessEase of UseSatisfaction

My husband was diagnosed 12years ago with ankylosis spondylitis and prescribed Ebrel. It worked great! 15 months ago it suddenly stopped working, or so we thought. Dr changed his melds but did not do any scans or X-rays. Wish he had. 12 months ago his collar bone broke spontaneously. He was using the mouse on his PC. At the emergency room they found shadows in his lungs. CT-Scan showed stage 4 metastasized lung cancer. 4 months ago he died at the age of 50. The rheumatologist never said this could happen. My husband left means two teenagers behind. They miss him very much. Read More Read Less

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 3.0

EffectivenessEase of UseSatisfaction

I had normal WBC counts before I was put on Enril for 3 months. My WBC dropped to 2.3, and I noticed my hair falling out during that time. My doctor immediately took me off the Enbril, and after being off a month my WBC count is now up to 4.2 and my hair has stopped falling out. I was previously on Humira with no known side effects, and hope to go back on it one my count goes higher.

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Fill 3Created with Sketch. Condition: Psoriasis associated with Arthritis

Overall rating 1.7

EffectivenessEase of UseSatisfaction

I’m much worse in all ways. My gait is like I’m a drunk and Gravity is is a strong second place hahah

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Fill 3Created with Sketch. Condition: Moderate to Severe Plaque Psoriasis

Overall rating 2.7

EffectivenessEase of UseSatisfaction

Started using Enbrel for psoriasis on my scalp. Worked very well…cleared up my skin. 7 months later I was diagnosed with chronic lymphocytic leukemia. About to start chemotherapy now. Do not take this drug…….

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 5. 0

EffectivenessEase of UseSatisfaction

I was diagnosed with lupus/severe arthritis after the birth of my daughter 21 years ago. I took methotrexate, plaquenil, and pred for three issues with terrible side effects scaling back to pred to have my second daughter. 6 mos after my second daughter was born, dr called telling me a about this trial drug. I immediately went on it because I couldn’t bear the thought of mehotrexate. It’s been 15 yrs! I made a decision that day for quality of life – I have my life back and I’ve raised two children doing all the crazy activities you do with kids! I’ve never had the side effects and I would fight my dr if she tried to take me off it! I started this drug at 38 and I’m 53 now. This drug gave me my life back and if I eventually develop a side effect, I still would not regret the decision I made. I’ve lived almost pain free for many years and once you lived with the severe pain of RA, you may think quality over quantity. It’s a personal decision only you can make for yourself but for me, I know I made the right one!Read More Read Less

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Fill 3Created with Sketch. Condition: Joint Inflammatory Disease in Children and Young Adults

Overall rating 2.0

EffectivenessEase of UseSatisfaction

My baby girl has JIA junior inflammatory arthritis. She was diagnosed at 6 month’s old now four years old and been on Enbrel for 2 and a half years along with methotrexate. We have no choice but to give it to her. With out it she’s paralyzed.I’m so afraid that what we’re giving her is gonna eventually take her life. Reading all these reviews breaks my heart. All I got is hope that this drug won’t take from us. I have two choices she can either be paralyzed and shrivel up to nothing or give her a drug that could potentially kill her. Wish there was a cure.Read More Read Less

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 4.7

EffectivenessEase of UseSatisfaction

Have been on Enbrel for over 10 years and has been effective, up until now. Doctor now suggests a new med, a non TNF blocker, to help relieve a now more active joint deteoriation.

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Fill 3Created with Sketch. Condition: Plaque Psoriasis

Overall rating 2.0

EffectivenessEase of UseSatisfaction

Developed severe antibody titre reaction. Three (3) months of therapy required to rehabilitate.

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Fill 3Created with Sketch. Condition: Rheumatoid Arthritis

Overall rating 4.7

EffectivenessEase of UseSatisfaction

I was one of the original users of this medication. I developed RA at 18, although I wasn’t diagnosed until 22 and was already in the “moderate to severe” category in every mobile joint in my body other than my spine. I tried everything on the market, and at best was only “surviving.” I also have Type I Diabetes, so I can’t take prednisone for flares (instantly develop high sugars that do not respond to correction). After I started taking a combination of methotrexate and Enbrel, I started having “okay” days. Then most days were okay, with a few “good” days. Then mostly “good” with some “what RA?” days. After faithfully taking this for 5+ years, I had to have some x-rays taken, and the radiologist noted that there was little to no evidence of RA in many of my joints! My only complaint is that the sure-click thingy injects way too fast and it hurts like hell for about 12 hours, in addition to an itchy lump under the skin. Annoying, but if I take it just before going to bed it’s a very tolerable side effect for the amount of relief I feel.Read More Read Less

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