Escitalopram side effects weight. Lexapro and Weight Changes: Causes, Effects, and Management Strategies
How does Lexapro affect weight. What are the potential side effects of escitalopram on appetite. Can Lexapro cause weight gain or loss. How to manage weight changes while taking Lexapro.
Understanding Lexapro: An Overview of Escitalopram
Lexapro, the brand name for escitalopram, is a widely prescribed medication belonging to the selective serotonin reuptake inhibitor (SSRI) class of antidepressants. Healthcare providers commonly recommend Lexapro for the treatment of mood disorders, particularly depression and anxiety. Its primary mechanism of action involves increasing serotonin levels in the brain, which plays a crucial role in regulating mood, appetite, and various other bodily functions.
Typically, doctors prescribe Lexapro in either liquid or pill form, with a standard dosage of 10 milligrams (mg) daily. Patients may take the medication in the morning or evening, depending on their preference and doctor’s recommendations. While some individuals may notice improvements in their symptoms within 1-4 weeks, it’s essential to continue the treatment as prescribed to maintain its effectiveness.
How does Lexapro work in the body?
Lexapro functions by inhibiting the reuptake of serotonin in the brain, effectively increasing the concentration of this neurotransmitter. This increase in serotonin levels helps regulate mood and can alleviate symptoms of depression and anxiety. However, the alteration in serotonin levels can also affect other bodily functions, including appetite regulation, which may lead to changes in weight.
Lexapro and Weight Changes: What Does the Research Say?
The relationship between Lexapro and weight changes has been a subject of considerable research and discussion in the medical community. While the medication’s prescribing information mentions the possibility of significant changes in weight and appetite, the extent and nature of these changes can vary widely among individuals.
Are weight changes common with Lexapro use?
Research findings on Lexapro’s impact on weight have been mixed. A 2014 study concluded that various antidepressants, including Lexapro, could lead to weight gain, but the differences among them were relatively small. The average weight gain for people taking Lexapro was less than 0.5%. Interestingly, young men and individuals with a lower body mass index (BMI) before starting treatment were more likely to experience significant weight gain.
A more recent review from 2018 compared weight changes across different antidepressants and found that the average weight gain with Lexapro was 3.7%. This figure falls within a range of weight changes observed with other antidepressants, from 1.1% with nortriptyline to 25.9% with amitriptyline.
Does Lexapro affect children and adolescents differently?
It’s worth noting that the effects of Lexapro on weight may differ between adults and younger populations. Some studies suggest that while adult humans are unlikely to see clinically significant changes in weight, children and adolescents using Lexapro may experience slower growth and weight gain. This highlights the importance of close monitoring when prescribing Lexapro to younger patients.
Factors Influencing Weight Changes on Lexapro
While Lexapro itself may influence weight, several other factors can contribute to weight changes during treatment. A 2017 study identified specific risk factors that increased the likelihood of weight gain when taking SSRIs like Lexapro:
- Sedentary lifestyle
- Smoking habits
- Diet high in processed meats, dairy, and refined carbohydrates
These findings suggest that lifestyle factors play a significant role in determining weight outcomes during Lexapro treatment. Additionally, the complex interplay between mood disorders and eating habits can further complicate the picture.
How do mood disorders affect eating habits?
Depression and anxiety can significantly impact an individual’s eating patterns. Some people may experience increased appetite and emotional eating as a coping mechanism, while others might lose interest in food and experience decreased appetite. As Lexapro begins to alleviate symptoms of depression or anxiety, these eating patterns may normalize, leading to changes in weight.
Potential Mechanisms Behind Lexapro-Related Weight Changes
The exact mechanisms by which Lexapro and other SSRIs affect weight are not fully understood. However, several theories have been proposed to explain the potential link between these medications and weight changes:
How does serotonin influence appetite and weight?
Serotonin plays a crucial role in regulating appetite and satiety. By increasing serotonin levels, Lexapro may directly influence appetite control centers in the brain. This could potentially lead to increased or decreased appetite, depending on the individual’s response to the medication.
Can improved mood affect eating habits?
As Lexapro begins to alleviate symptoms of depression or anxiety, individuals may experience changes in their eating habits. Some people might find themselves eating more as their mood improves and they regain interest in food and daily activities. Conversely, others might experience a decrease in stress-related or emotional eating, leading to weight loss.
Managing Weight Changes While Taking Lexapro
For individuals concerned about potential weight changes while taking Lexapro, there are several strategies that can help maintain a healthy weight:
- Maintain a balanced diet: Focus on consuming a variety of nutrient-dense foods, including fruits, vegetables, lean proteins, and whole grains.
- Regular exercise: Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week.
- Monitor portion sizes: Be mindful of portion sizes and practice mindful eating techniques.
- Stay hydrated: Drink plenty of water throughout the day to support overall health and potentially curb unnecessary snacking.
- Get adequate sleep: Aim for 7-9 hours of quality sleep per night, as poor sleep can affect appetite and metabolism.
- Stress management: Practice stress-reduction techniques such as meditation, yoga, or deep breathing exercises.
- Regular check-ins with healthcare provider: Discuss any concerns about weight changes with your doctor and consider regular weigh-ins to track trends.
When should you consult your doctor about weight changes?
It’s important to communicate with your healthcare provider about any significant weight changes while taking Lexapro. If you experience rapid weight gain or loss, or if weight changes are causing distress or affecting your overall health, consult your doctor. They may adjust your dosage, consider alternative medications, or provide additional strategies to manage weight while continuing your treatment.
Lexapro Compared to Other Antidepressants: Weight Change Profiles
When considering the potential for weight changes, it’s helpful to compare Lexapro with other antidepressants. While individual responses can vary greatly, some general trends have been observed in research studies:
How do SSRIs compare to older antidepressants in terms of weight gain?
SSRIs like Lexapro are generally considered to have a lower risk of weight gain compared to older classes of antidepressants, such as monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs). However, weight changes can still occur with SSRIs, and the extent of these changes may vary among different medications within the SSRI class.
Are there antidepressants less likely to cause weight gain?
Some antidepressants are associated with a lower risk of weight gain or may even promote weight loss in some individuals. These include bupropion (Wellbutrin) and fluoxetine (Prozac). However, it’s important to note that the effectiveness of an antidepressant for treating mood disorders should be the primary consideration when choosing a medication, with side effects being a secondary factor.
Long-Term Effects of Lexapro on Weight and Metabolism
While much of the research on Lexapro and weight changes focuses on short-term effects, it’s also important to consider the potential long-term impacts of the medication on weight and metabolism.
Does weight gain on Lexapro plateau over time?
Some studies suggest that weight gain associated with antidepressants, including Lexapro, may plateau after the first few months of treatment. However, long-term data on this topic is limited, and individual experiences may vary. Continued monitoring and lifestyle management remain important throughout the duration of treatment.
Can Lexapro affect metabolic health?
There is ongoing research into the potential effects of SSRIs on metabolic health. Some studies have suggested that long-term use of antidepressants may be associated with an increased risk of metabolic syndrome, which includes factors such as increased waist circumference, high blood pressure, and altered lipid profiles. However, more research is needed to fully understand these potential long-term effects and their clinical significance.
Discontinuing Lexapro: Weight Considerations and Tapering
If you and your healthcare provider decide to discontinue Lexapro treatment, it’s important to approach the process carefully and consider potential effects on weight and overall health.
How should Lexapro be discontinued safely?
Abruptly stopping Lexapro can lead to discontinuation symptoms and potentially affect mood and appetite. It’s crucial to work with your healthcare provider to develop a tapering plan that gradually reduces your dosage over time. This approach can help minimize withdrawal symptoms and allow your body to adjust more smoothly.
Can discontinuing Lexapro lead to weight changes?
Some individuals may experience changes in weight or appetite when discontinuing Lexapro. These changes can be due to a variety of factors, including the body’s readjustment to pre-treatment serotonin levels, changes in mood, and alterations in eating habits. Monitoring your weight and maintaining healthy lifestyle habits during the discontinuation process can help manage any potential changes.
In conclusion, while Lexapro can potentially affect weight in some individuals, the extent and nature of these changes can vary widely. By understanding the potential effects, maintaining open communication with healthcare providers, and implementing healthy lifestyle strategies, individuals can better manage their weight while benefiting from the mood-stabilizing effects of Lexapro. Remember that the primary goal of antidepressant treatment is to improve mental health and overall quality of life, and any concerns about side effects should be discussed with a healthcare professional.
Lexapro and weight gain or loss: Facts and tips
Lexapro and weight gain or loss: Facts and tips
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Medically reviewed by Alan Carter, Pharm. D. — By Claire Sissons — Updated on December 22, 2022
Lexapro is the brand name for escitalopram, which doctors prescribe to treat anxiety and depression. It increases serotonin in the brain, which can affect your appetite and may lead to weight changes.
Lexapro belongs to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). Doctors may prescribe it to treat mood disorders, such as depression and anxiety.
In this article, we look at how Lexapro can affect appetite and weight and some tips for managing weight change.
Lexapro’s prescribing information states that people using the drug to treat major depression may experience significant changes in weight and appetite. These include both increases and decreases.
The leaflet cites animal studies in which significant weight gain occurred. However, at least one study has suggested that adult humans are unlikely to see clinically significant changes, while children and adolescents using Lepraxo may have slower growth and weight gain.
The authors of a 2014 study concluded that various antidepressants could lead to weight gain, but the differences among them were relatively small. The average weight gain for people taking Lexapro was less than 0.5%.
The most significant weight gain occurred in young men and those whose body mass index (BMI) was low before starting treatment.
A 2018 review also compared weight changes with various antidepressants and concluded that the average weight gain with Lexapro was 3.7%. Weight gain with other options ranged from 1.1% with nortriptyline to 25.9% with amitriptyline.
Research from 2017 looked at the role of SSRIs in weight gain. The authors found that certain risk factors increased the likelihood of a person gaining weight when taking these antidepressants. These factors included:
- having a sedentary lifestyle
- smoking
- eating a diet high in processed meat, dairy, and refined carbohydrates
SSRIs may be less likely than older antidepressants — such as monoamine oxidase inhibitors and tricyclic antidepressants — to cause weight gain.
Meanwhile, the National Library of Medicine lists decreased appetite as a side effect of Lexapro and does not mention weight gain.
Why do antidepressants affect weight?
Experts do not know precisely why weight changes occur with antidepressant use.
One reason may be that they boost serotonin, which plays a role in managing appetite. The medication may increase appetite directly, or a person may begin to eat more as their depression or anxiety lessens.
Depression and anxiety can also affect eating habits — people may eat more or less than usual. Lifestyle remedies, such as changes in diet and exercise, may also affect a person’s appetite and weight.
More research is needed to identify what connection, if any, exists between SSRIs and weight gain.
SSRIs work by increasing the amount of serotonin in the brain. Serotonin is a hormone and neurotransmitter that helps regulate mood.
Lexapro comes as either a liquid or a pill. The dosage is usually 10 milligrams (mg) daily, taken either in the morning or the evening.
A person may notice an improvement in symptoms after 1–4 weeks, but they should continue taking the drug, or symptoms may return. People should not stop taking Lexapro without guidance from a doctor.
Medication affects everyone differently.
Anyone concerned about weight changes while taking Lexapro should speak with a doctor.
A doctor may do further tests to see if there is another reason for the change in weight. If there is no other reason, they may suggest an alternative treatment.
Other remedies for treating depression include:
- undergoing counseling
- exercising, such as walking at least 30 minutes each day
- following a varied diet and eating regular meals
- establishing or maintaining a regular sleep pattern
- connecting with others
- avoiding the use of alcohol, nicotine, and drugs that a doctor has not recommended
These measures can help a person feel better, and some may help manage weight.
Lexapro can cause other side effects, which may include:
- a dry mouth
- abdominal pain
- diarrhea or constipation
- heartburn
- feeling dizzy
- nausea
- feeling more tired or drowsy than usual
- changes in sex drive
- changes in urination
- sweating more than usual
- symptoms that are similar to flu, such as a runny nose or fever
If these side effects do not go away or are very severe, a person should seek medical advice.
Some side effects, including the following, can be serious and require urgent medical attention:
- worsening depression or thinking about or attempting suicide
- hallucinations
- agitation, racing thoughts, and unusually high energy levels, which are signs of mania
- a fast or irregular heartbeat, stiff or twitching muscles, confusion, and fever, which can indicate serotonin syndrome
- breathing difficulty, hives, and swelling, which may indicate an allergic reaction
- eye or vision changes
All SSRIs have slightly different side effects. If the side effects of an antidepressant are affecting a person’s quality of life, they might benefit from trying an alternative drug.
Learn more about Lexapro’s side effects.
Suicide prevention
If you know someone at immediate risk of self-harm, suicide, or hurting another person:
- Ask the tough question: “Are you considering suicide?”
- Listen to the person without judgment.
- Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
- Stay with the person until professional help arrives.
- Try to remove any weapons, medications, or other potentially harmful objects.
If you or someone you know is having thoughts of suicide, a prevention hotline can help. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988.
Click here for more links and local resources.
Was this helpful?
Here are some answers to questions people often ask about Lexapro (escitalopram) and weight gain.
Can Lexapro cause rapid weight gain?
Lexapro may cause a small amount of weight gain. If rapid or dramatic weight gain occurs, a person should speak with their doctor.
How much weight do you gain on Lexapro?
The effects of Lexapro on weight will vary among individuals. A 2014 study found that the average weight gain was less than 0.5%, but a 2018 review put the average weight gain at 3.7%.
Does Lexapro slow your metabolism?
Metabolic changes can occur when a person has depression and is taking antidepressant medications. However, the relationships are complex, and there is not enough evidence to show that Lepraxo specifically affects metabolism.
How can I avoid gaining weight on Lexapro?
Ways of managing weight while taking Lepraxo include:
- following a varied diet with plenty of fresh ingredients
- avoiding high fat, high sugar foods
- eating regular meals and healthy snacks
- getting regular exercise
- receiving counseling to help manage both depression and weight issues
Anyone concerned about their weight should ask a healthcare professional about how to manage it.
Which foods can help manage depression?
Weight changes can occur when taking Lexapro, but they are not usually dramatic. In some cases, weight loss may occur. A doctor may monitor a child taking this drug for reduced growth rates and insufficient weight gain.
Anyone with concerns about weight gain while taking Lexapro may wish to seek advice from a doctor, who might offer an alternative medication.
A varied, balanced diet and regular exercise are also treatment options for depression and anxiety, and they can help manage weight changes.
Last medically reviewed on October 17, 2022
- Depression
- Obesity / Weight Loss / Fitness
- Pharmacy / Pharmacist
- Psychology / Psychiatry
How we reviewed this article:
Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
- Blumenthal, S. R., et al. (2014). An electronic health records study of long-term weight gain following antidepressant use.
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/1878922 - Care for your health. (n.d.).
http://www.mentalhealthamerica.net/care-your-health - Depression: Overview. (2022).
https://www.nimh.nih.gov/health/topics/depression#part_2257 - Eker, O. O., et al. (2017). Metabolic effects of antidepressant treatment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439472/ - Escitalopram. (2022).
https://medlineplus.gov/druginfo/meds/a603005.html - ESCITALOPRAM tablets, for oral use. (2020).
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=61f27814-bc32-4de5-b12a-29fe1ee9771e - Gafoor, R. , et al. (2018). Antidepressant utilisation and incidence of weight gain during 10 years’ follow-up: population based cohort study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964332/ - Healthy diet: Eating with mental health in mind. (n.d.).
http://www.mentalhealthamerica.net/conditions/healthy-diet-eating-mental-health-mind - Shi, Z., et al. (2017). SSRI antidepressant use potentiates weight gain in the context of unhealthy lifestyles: Results from a 4-year Australian follow-up study.
https://bmjopen.bmj.com/content/7/8/e016224
Share this article
Medically reviewed by Alan Carter, Pharm.D. — By Claire Sissons — Updated on December 22, 2022
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Lexapro and weight gain or loss: Facts and tips
Lexapro and weight gain or loss: Facts and tips
- Health Conditions
- Health Conditions
- Alzheimer’s & Dementia
- Anxiety
- Asthma & Allergies
- Atopic Dermatitis
- Breast Cancer
- Cancer
- Cardiovascular Health
- COVID-19
- Diabetes
- Environment & Sustainability
- Exercise & Fitness
- Eye Health
- Headache & Migraine
- Health Equity
- HIV & AIDS
- Human Biology
- Leukemia
- LGBTQIA+
- Men’s Health
- Mental Health
- Multiple Sclerosis (MS)
- Nutrition
- Parkinson’s Disease
- Psoriasis
- Psoriatic Arthritis
- Sexual Health
- Ulcerative Colitis
- Women’s Health
- Health Conditions
- Health Products
- Health Products
- Nutrition & Fitness
- Vitamins & Supplements
- CBD
- Sleep
- Mental Health
- At-Home Testing
- Men’s Health
- Women’s Health
- Health Products
- Discover
- News
- Latest News
- Original Series
- Medical Myths
- Honest Nutrition
- Through My Eyes
- New Normal Health
- Podcasts
- Why Parkinson’s research is zooming in on the gut
- Can diet and exercise reverse prediabetes?
- Investigating the power of music for dementia
- How diet may help with endometriosis
- Is the ketogenic diet right for autoimmune conditions?
- Can diet help improve depression symptoms?
- News
- Tools
- General Health
- Drugs A-Z
- Health Hubs
- Health Tools
- BMI Calculators and Charts
- Blood Pressure Chart: Ranges and Guide
- Breast Cancer: Self-Examination Guide
- Sleep Calculator
- Quizzes
- RA Myths vs Facts
- Type 2 Diabetes: Managing Blood Sugar
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- About Medical News Today
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- Newsletters
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Medically reviewed by Alan Carter, Pharm. D. — By Claire Sissons — Updated on December 22, 2022
Lexapro is the brand name for escitalopram, which doctors prescribe to treat anxiety and depression. It increases serotonin in the brain, which can affect your appetite and may lead to weight changes.
Lexapro belongs to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). Doctors may prescribe it to treat mood disorders, such as depression and anxiety.
In this article, we look at how Lexapro can affect appetite and weight and some tips for managing weight change.
Lexapro’s prescribing information states that people using the drug to treat major depression may experience significant changes in weight and appetite. These include both increases and decreases.
The leaflet cites animal studies in which significant weight gain occurred. However, at least one study has suggested that adult humans are unlikely to see clinically significant changes, while children and adolescents using Lepraxo may have slower growth and weight gain.
The authors of a 2014 study concluded that various antidepressants could lead to weight gain, but the differences among them were relatively small. The average weight gain for people taking Lexapro was less than 0.5%.
The most significant weight gain occurred in young men and those whose body mass index (BMI) was low before starting treatment.
A 2018 review also compared weight changes with various antidepressants and concluded that the average weight gain with Lexapro was 3.7%. Weight gain with other options ranged from 1.1% with nortriptyline to 25.9% with amitriptyline.
Research from 2017 looked at the role of SSRIs in weight gain. The authors found that certain risk factors increased the likelihood of a person gaining weight when taking these antidepressants. These factors included:
- having a sedentary lifestyle
- smoking
- eating a diet high in processed meat, dairy, and refined carbohydrates
SSRIs may be less likely than older antidepressants — such as monoamine oxidase inhibitors and tricyclic antidepressants — to cause weight gain.
Meanwhile, the National Library of Medicine lists decreased appetite as a side effect of Lexapro and does not mention weight gain.
Why do antidepressants affect weight?
Experts do not know precisely why weight changes occur with antidepressant use.
One reason may be that they boost serotonin, which plays a role in managing appetite. The medication may increase appetite directly, or a person may begin to eat more as their depression or anxiety lessens.
Depression and anxiety can also affect eating habits — people may eat more or less than usual. Lifestyle remedies, such as changes in diet and exercise, may also affect a person’s appetite and weight.
More research is needed to identify what connection, if any, exists between SSRIs and weight gain.
SSRIs work by increasing the amount of serotonin in the brain. Serotonin is a hormone and neurotransmitter that helps regulate mood.
Lexapro comes as either a liquid or a pill. The dosage is usually 10 milligrams (mg) daily, taken either in the morning or the evening.
A person may notice an improvement in symptoms after 1–4 weeks, but they should continue taking the drug, or symptoms may return. People should not stop taking Lexapro without guidance from a doctor.
Medication affects everyone differently.
Anyone concerned about weight changes while taking Lexapro should speak with a doctor.
A doctor may do further tests to see if there is another reason for the change in weight. If there is no other reason, they may suggest an alternative treatment.
Other remedies for treating depression include:
- undergoing counseling
- exercising, such as walking at least 30 minutes each day
- following a varied diet and eating regular meals
- establishing or maintaining a regular sleep pattern
- connecting with others
- avoiding the use of alcohol, nicotine, and drugs that a doctor has not recommended
These measures can help a person feel better, and some may help manage weight.
Lexapro can cause other side effects, which may include:
- a dry mouth
- abdominal pain
- diarrhea or constipation
- heartburn
- feeling dizzy
- nausea
- feeling more tired or drowsy than usual
- changes in sex drive
- changes in urination
- sweating more than usual
- symptoms that are similar to flu, such as a runny nose or fever
If these side effects do not go away or are very severe, a person should seek medical advice.
Some side effects, including the following, can be serious and require urgent medical attention:
- worsening depression or thinking about or attempting suicide
- hallucinations
- agitation, racing thoughts, and unusually high energy levels, which are signs of mania
- a fast or irregular heartbeat, stiff or twitching muscles, confusion, and fever, which can indicate serotonin syndrome
- breathing difficulty, hives, and swelling, which may indicate an allergic reaction
- eye or vision changes
All SSRIs have slightly different side effects. If the side effects of an antidepressant are affecting a person’s quality of life, they might benefit from trying an alternative drug.
Learn more about Lexapro’s side effects.
Suicide prevention
If you know someone at immediate risk of self-harm, suicide, or hurting another person:
- Ask the tough question: “Are you considering suicide?”
- Listen to the person without judgment.
- Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
- Stay with the person until professional help arrives.
- Try to remove any weapons, medications, or other potentially harmful objects.
If you or someone you know is having thoughts of suicide, a prevention hotline can help. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988.
Click here for more links and local resources.
Was this helpful?
Here are some answers to questions people often ask about Lexapro (escitalopram) and weight gain.
Can Lexapro cause rapid weight gain?
Lexapro may cause a small amount of weight gain. If rapid or dramatic weight gain occurs, a person should speak with their doctor.
How much weight do you gain on Lexapro?
The effects of Lexapro on weight will vary among individuals. A 2014 study found that the average weight gain was less than 0.5%, but a 2018 review put the average weight gain at 3.7%.
Does Lexapro slow your metabolism?
Metabolic changes can occur when a person has depression and is taking antidepressant medications. However, the relationships are complex, and there is not enough evidence to show that Lepraxo specifically affects metabolism.
How can I avoid gaining weight on Lexapro?
Ways of managing weight while taking Lepraxo include:
- following a varied diet with plenty of fresh ingredients
- avoiding high fat, high sugar foods
- eating regular meals and healthy snacks
- getting regular exercise
- receiving counseling to help manage both depression and weight issues
Anyone concerned about their weight should ask a healthcare professional about how to manage it.
Which foods can help manage depression?
Weight changes can occur when taking Lexapro, but they are not usually dramatic. In some cases, weight loss may occur. A doctor may monitor a child taking this drug for reduced growth rates and insufficient weight gain.
Anyone with concerns about weight gain while taking Lexapro may wish to seek advice from a doctor, who might offer an alternative medication.
A varied, balanced diet and regular exercise are also treatment options for depression and anxiety, and they can help manage weight changes.
Last medically reviewed on October 17, 2022
- Depression
- Obesity / Weight Loss / Fitness
- Pharmacy / Pharmacist
- Psychology / Psychiatry
How we reviewed this article:
Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
- Blumenthal, S. R., et al. (2014). An electronic health records study of long-term weight gain following antidepressant use.
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/1878922 - Care for your health. (n.d.).
http://www.mentalhealthamerica.net/care-your-health - Depression: Overview. (2022).
https://www.nimh.nih.gov/health/topics/depression#part_2257 - Eker, O. O., et al. (2017). Metabolic effects of antidepressant treatment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439472/ - Escitalopram. (2022).
https://medlineplus.gov/druginfo/meds/a603005.html - ESCITALOPRAM tablets, for oral use. (2020).
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=61f27814-bc32-4de5-b12a-29fe1ee9771e - Gafoor, R. , et al. (2018). Antidepressant utilisation and incidence of weight gain during 10 years’ follow-up: population based cohort study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964332/ - Healthy diet: Eating with mental health in mind. (n.d.).
http://www.mentalhealthamerica.net/conditions/healthy-diet-eating-mental-health-mind - Shi, Z., et al. (2017). SSRI antidepressant use potentiates weight gain in the context of unhealthy lifestyles: Results from a 4-year Australian follow-up study.
https://bmjopen.bmj.com/content/7/8/e016224
Share this article
Medically reviewed by Alan Carter, Pharm.D. — By Claire Sissons — Updated on December 22, 2022
Related Coverage
- What are depression screening tools?
Healthcare professionals use depression screening tools to enable early detection and assessment. Learn more.
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dullness of emotions, swelling, weight gain, decreased libido
Medicine and health
Reader Experience
These are community reader comments. Collected into one material, carefully edited and formatted according to editorial standards.
Julia Konyakhina
collected stories
Author profile
Antidepressants can cause unpleasant symptoms, especially at the beginning of treatment.
Most of them are not dangerous and weaken after a few weeks. But some pass only after completion of therapy or a change in the drug. We asked readers to tell us what side effects of antidepressants they had to deal with and how they coped with it.
Go to the doctor
There are no recommendations for treatment in the article, only personal experience of readers. Please consult with your doctor before deciding on treatment. The responsibility for your health rests solely with you.
Side effect No. 1
Dullness of emotions
Ksenia M
completed treatment
She took Paxil antidepressant in combination with an antipsychotic. In the first week of therapy, there were very strange sensations: emotions and feelings became dull, it seemed that I was in a vacuum.
There was also a strong thirst, libido dropped below the baseboard, I constantly wanted to sleep. A month later, the side effects disappeared, and after three months, the first improvements in mental state appeared.
Totally treated with an antidepressant for a year, after completion of therapy, there was no withdrawal syndrome.
Anna
stopped treatment
The doctor diagnosed her with generalized anxiety disorder and prescribed Paxil. I drank 1/4 of the tablet, after a couple of hours there was wild anxiety, a feeling of a lump in my throat and nausea. Fell asleep. Waking up, I felt like a vegetable: nothing irritates, does not please, all emotions are so muffled that they seem to be non-existent. She did not take the drug anymore.
Infestor
transformed
Suffered from anxiety-panic disorder, took escitalopram for about two years.
There was a feeling that the drug dulled the senses: because of it, I really felt like I didn’t give a damn. I came to the conclusion that during therapy it is better not to build a relationship with a person who is not in the subject, because it is difficult to show emotions. It seems that the partner is sexually attracted, you enjoy spending time with him, but you cannot fully express your feelings.
After treatment, the situation returned to normal. Now I feel great, I lead an active lifestyle, I go in for sports intensively. He became more collected in work and, in general, seemed to be born again.
Side effect No. 2
Weight gain
Kutro
worried about being overweight
I have been taking the antidepressant paroxetine along with the neuroleptic thioridazine for about six months. It helps well, but there is a side effect: I gained a lot of extra pounds. I have been thin all my life, and now I feel uncomfortable at the new weight.
Side effect No. 3
Decreased libido
Wintermute
already normal
I took Velaxin. At the beginning of the reception, I felt sick and had a stomach ache, as if an ulcer was exacerbated. But that’s okay. The main side effect is completely cut off libido and sensitivity. That you stroke your knee, that intimate places – everything is one. After the drug was discontinued, everything returned to normal, but it was scary.
Stefano
continues treatment
For nine months he took the antidepressant “Cipralex” along with the tranquilizer “Atarax”. Thanks to the treatment, he returned to normal life. Of the side effects were unusual dreams, decreased libido and difficulty achieving orgasm.
After moving to another country, he turned to a new psychiatrist, who decided to replace Cipralex with Zoloft. From the last libido decreased even more, sexual intercourse became very long. After discontinuation of the drug, the negative effects persisted. As a result, I returned to Cipralex, I hope everything will be restored with time.
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Side effect No. 4
diarrhea
Flame
took SioSC
Goloft. The first two weeks I had diarrhea, then everything went away. There were also difficulties in achieving orgasm, while libido remained normal.
Green-eyed
experienced only one side effect
Was treated with Cipralex for a year. The first five days there was loose stools, there were no more side effects. The mood improved, anxiety and irritability disappeared.
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Side effect No. 5
Problems with sleep
Aliya Abdullina
did not sleep well
When I took and duloxetine, there were problems with sleep. She fell asleep normally, but after four or five hours she woke up and then slept fitfully, restlessly, after waking up she did not feel rested. Even during the day, the brain seemed to turn off, my limbs twitched, as if in a fast phase of sleep.
The doctor changed the regimen of taking the drug, it got better, but I still can’t sleep during the day, even if I really want to. As soon as I fall into a dream, I immediately wake up.
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Everything else is fine. Weight and appetite did not change during therapy. Libido decreased, but quickly recovered. At the very beginning of the treatment, there was a lump in the throat, which was rather unpleasant, but this did not last long – five days.
user1331271
had unpleasant dreams
While on antidepressants, she suffered from nightmares and sometimes had very strange vivid dreams. The side effects were fully manifested when the doctor changed the dosage.
burnet
slept for two days
Suffered from insomnia and eating problems. The doctor diagnosed an anxiety-depressive disorder and prescribed mirtazapine.
I did not notice any changes in my mental state. My appetite didn’t wake up, sleep problems generally worsened: I took medicine before going to bed, and then lay half the night looking at the ceiling. Waking up in the morning was a hell of a lot, just like sitting through working hours in the office. But by the evening, I magically became cheerful. This was repeated from day to day.
I don’t remember how long I abused myself by continuing to take the drug. But I remember that once I came home on Friday, sat down on the sofa and woke up on Sunday evening, and a little later fell asleep again until Monday.
Throughout the therapy it seemed that I did not exist: I either sleep, or I try to sleep, or, on the contrary, I struggle with sleep.
Side effect no. 6
Thirst and swelling
Beauty master
no longer panics
I drank the antidepressant “Serenata” and an antipsychotic. I suffered from terrible thirst. She got up several times during the night to drink, and by morning she was swollen like a beekeeper who fell asleep face down in a hive.
For the first two weeks of therapy, the head was like in a fog, then it went away. I gained six or seven kilograms in weight. But thanks to the treatment, her mental state returned to normal: she began to sleep better, learned to control panic.
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Side effect No. 7
Nausea
Daria
was not very worried about side effects
The doctor prescribed Serenata because of sleep problems: I didn’t sleep much, and if I fell asleep, I had nightmares. Of the side effects, there was a slight nausea, but it did not bother me much and passed after a couple of weeks. On the second day of therapy, the face was swollen. I didn’t notice anything else that was bad.
Side effect #8
Anxiety
Ninja Turtle
thought about suicide
Took antidepressants three times. The first was Paxil. He was discharged without tranquilizers, so in the very first days of therapy he was seized with wild anxiety, it came to thoughts of suicide. The doctor added a tranquilizer and the anxiety went away. But short-term memory and attention broke down.
As a result, I was transferred to Cipramil. Because of him, libido disappeared, the menstrual cycle flew off and constipation began. At the same time, the mood, as it was below the plinth, remained the same. Six months later, Anafranil was prescribed. Libido recovered, other side effects persisted. But psychologically, I felt much better, even changed jobs during therapy.
What is depression?
Word by word
found the optimal dose of the drug
I took fluvoxamine for six months because of an anxiety-depressive disorder. At the beginning of therapy, anxiety increased markedly for no significant reason. A month later, the dosage of the drug was increased. At first I felt fine, but after three weeks a very unpleasant symptom appeared – tension in the body that I could not control. As a result, the dosage had to be reduced again, after which the state of health returned to normal.
Side effect no. 9
Decreased concentration
Mot
does not complain
Took mirtazapine. It was as if drunk from him. Now I’m taking Cipralex. Distractedness and drowsiness torment from time to time. But these symptoms are nothing compared to what I experienced due to generalized anxiety disorder.
Side effect No. 10
Excessive arousal
Olga Selivanova
experienced a rare side effect
Euphoria was a side effect of my therapy. Against the background of a long-term lowered mood, colors seem to have returned to life: the world has become brighter even visually. I wanted to sing, dance and hug everyone right on the street. The effect lasted about a week, then passed. The doctor said that this is quite rare.
Six months after the treatment, I managed to feel something similar – when you get up in the morning, and you are in a good mood and have strength, and by default you feel somehow calm and good.
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Escitalopram: Pediatric Medication | Memorial Sloan Kettering Cancer Center
Pediatric Medicine
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This document provided by Lexicomp ® contains all the information you need to know about the drug, including indications, directions for use, side effects, and when you should contact your healthcare provider.
Trade names: USA
Lexapro
Trade names: Canada
ACH-Escitalopram; ACT Escitalopram ODT; AG-Escitalopram; APO Escitalopram; Auro Escitalopram; BIO-Escitalopram; Cipralex; KYE-Escitalopram; M-Escitalopram; Mar-Escitalopram; MINT-Escitalopram; MYLAN-Escitalopram; NAT-Escitalopram; NRA-Escitalopram; PMS-Escitalopram; PMSC-Escitalopram; RIVA Escitalopram; SANDOZ Escitalopram; TARO-Escitalopram; TEVA-Escitalopram
Warning
- Drugs like this have increased the likelihood of suicidal thoughts or actions in children and young people. This risk may be higher in people who have tried or had suicidal thoughts in the past. All people taking this drug must be closely monitored. If you develop or worsen disorders such as depression, nervousness, anxiety, grouchiness, panic attacks, and changes in mood or behavior, contact your doctor immediately. Contact your doctor immediately if you have suicidal thoughts or suicide attempts.
- This drug is not approved for use in children of all ages. Check with your doctor to make sure this drug is right for your child.
What is this drug used for?
- Used to treat depression.
- Used to treat anxiety.
- This drug can be given to children for other indications. Consult your doctor.
What do I need to tell the doctor BEFORE my child takes this drug?
- If your child has an allergy to this drug, any of its ingredients, other drugs, foods, or substances. Tell the doctor about the allergy and how it manifested itself in the child.
- If the child is receiving any of the following drugs: linezolid or methylene blue.
- If your child is taking any of these drugs: citalopram or pimozide.
- If your child has taken medications for depression or certain other illnesses in the last 14 days. These include isocarboxazid, phenelzine, and tranylcypromine. An episode of very high blood pressure may occur.
This list of drugs and conditions that may interact unfavorably with this drug is not exhaustive.
Talk to your doctor or pharmacist about all medicines your child is taking (prescription and over-the-counter, natural, and vitamins) and any health problems. You need to make sure that this drug is safe to use for your child’s illnesses and in combination with other drugs he or she is already taking. Do not start, stop taking, or change the dosage of any drug your child is taking without the doctor’s approval.
What do I need to know or do while my child is taking this drug?
- Tell all health care providers who care for your child that your child is taking this drug. These are your child’s doctors, nurses, pharmacists and dentists.
- Have your child avoid tasks or activities that require attention until you see how this drug works for your child. This includes cycling, playing sports, or using items such as scissors, lawn mowers, electric scooters, toy cars, or motorized vehicles.
- Do not stop giving this drug to your child abruptly without talking to the doctor. This can increase your child’s risk of side effects. If needed, this drug should be stopped gradually for your child as directed by the doctor.
- Alcohol can interact with this drug. Make sure your child does not drink alcohol.
- Check with your child’s doctor before using marijuana, other forms of cannabis, or prescription or over-the-counter drugs that may slow your child’s progress.
- Depression may improve sleep and appetite quickly after starting this drug. It may take up to 4 weeks to relieve other symptoms of depression.
- This drug may increase the risk of bleeding. Sometimes bleeding can be life-threatening. Consult your doctor.
- This drug may cause low sodium levels. Very low sodium levels can be life-threatening, leading to convulsions, fainting, difficulty breathing, or death.
- In some cases, the drug may affect the growth rate in children and adolescents. They may need regular growth rate checks. Consult your doctor.
If your daughter is pregnant or breastfeeding:
- Consult physician if your daughter is pregnant, pregnant, or breastfeeding. The benefits and risks for your daughter and her baby will need to be discussed.
- Taking this drug during the third trimester of pregnancy may cause some health problems in the newborn. Consult your doctor.
What side effects should I report to my child’s doctor right away?
WARNING/CAUTION: Although rare, some people may have very serious and sometimes deadly side effects of this drug. Call your child’s doctor right away or seek medical attention if your child has any of the following signs or symptoms that could be associated with a very bad side effect:
- Signs of an allergic reaction, such as rash, hives, itching, red and swollen skin with blisters or peeling, possibly accompanied by fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue or throat.
- Signs of low sodium levels such as headache, trouble concentrating, memory impairment, confused thinking, weakness, seizures, problems with balance.
- signs of bleeding, such as vomiting or coughing up blood; vomiting of the type of coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; non-cyclic vaginal bleeding; bruises that appear or increase for no reason; bleeding that you cannot stop.
- Seizures.
- Fever or chills.
- Painful erections or erections that last more than 4 hours.
- Some patients may be at increased risk of eye problems when using this drug. Your child’s doctor may schedule an eye exam to see if your child is at increased risk for these eye problems. Call your doctor right away if your child has eye pain, vision changes, swelling, or redness around the eye.
- A severe and sometimes deadly complication called serotonin syndrome can occur. This risk may be increased if the child is also taking certain other drugs. Call your child’s healthcare provider right away if your child has agitation, balance problems, confusion, hallucinations, high fever, tachycardia or abnormal heart rhythm, flushing, muscle twitching or stiffness, seizures, tremors or tremors, excessive sweating, severe diarrhea, nausea or vomiting, a very severe headache.
If your child is or may be sexually active:
- Against the background of taking such drugs, violations of sexual function were noted. These included decreased interest in sex, problems achieving orgasm, problems ejaculating, or problems getting or maintaining an erection. If you have any questions, please consult your doctor.
What are some other side effects of this drug?
Any drug can have side effects. However, for many people, side effects are either minor or non-existent. Contact your child’s doctor or seek medical attention if any of these or other side effects bother your child or if they persist:
- Feeling dizzy, drowsy, tired or weak.
- Headache.
- Nausea.
- Sleep disorders.
- Dry mouth.
- Diarrhea or constipation.
- Excessive sweating.
- Flu-like symptoms.
- Runny nose.
- Yawn.
This list of possible side effects is not exhaustive. If you have any questions about side effects, ask your child’s doctor. Talk to your child’s doctor about side effects.
You can report side effects to the National Health Board.
What is the best way to give this drug?
Give this drug to your child as directed by your doctor. Read all the information provided to you. Strictly follow all instructions.
All forms:
- Give this drug with or without food.
- Keep giving this drug as directed by your child’s doctor or other health care provider, even if your child is feeling well.
Oral solution:
- Liquid doses should be measured with caution. Use the dispenser that comes with the medicine. If the dispenser is not provided in the package, ask the pharmacist for a dosing agent for this drug.
What if my child misses a dose of medication?
- Give the missed dose as soon as possible.
- If it is time for your child to take the next dose, do not take the missed dose and then go back to your child’s normal schedule.
- Do not give a double dose at the same time or additional doses.
How do I store and/or discard this drug?
- Store at room temperature in a dry place. Do not store in the bathroom.
- Keep all medicines in a safe place. Keep all medicines out of the reach of children and pets.
- Dispose of unused or expired drugs. Do not empty into a toilet or sewer unless instructed to do so. If you have any questions about disposing of medicines, ask your pharmacist. Drug disposal programs may be in place in your area.
General drug information
- If your child’s symptoms or health problems do not improve, or worsen, contact your child’s doctor.
- Do not share your child’s medicine with others and do not give anyone else’s medicine to your child.
- Some medicines may come with other patient information leaflets. If you have questions about this drug, talk with your child’s doctor, nurse, pharmacist, or other health care professional.
- If you think you have overdosed, call a poison control center or get medical help right away. Be prepared to tell or show what drug you took, how much, and when it happened.
Consumer Use of Information and Limitation of Liability
This summary information includes summaries of diagnosis, treatment, and/or drug product. It is not intended to be a comprehensive source of data and should be used as a tool to help the user understand and/or evaluate potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a particular patient. It should not be considered medical advice or a substitute for medical advice, diagnosis or treatment provided by a physician based on a medical examination and assessment of the patient’s specific and unique circumstances.