About all

Levonorgestrel and Ethinyl Estradiol: Comprehensive Guide to Side Effects and Usage

What are the main side effects of Levonorgestrel and Ethinyl Estradiol. How does this medication work to prevent pregnancy. What are the proper usage instructions for this oral contraceptive. When should you seek medical attention while taking this medication.

Understanding Levonorgestrel and Ethinyl Estradiol: A Powerful Combination for Birth Control

Levonorgestrel and Ethinyl Estradiol is a combination hormone medication primarily used for preventing pregnancy. This oral contraceptive contains two key hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). Together, these hormones work synergistically to provide effective birth control.

Beyond its primary function, this medication offers several additional benefits. These include:

  • Regulating menstrual cycles
  • Reducing blood loss during periods
  • Alleviating menstrual pain
  • Decreasing the risk of ovarian cysts
  • Treating acne

It’s crucial to note that while this medication is highly effective at preventing pregnancy, it does not protect against sexually transmitted diseases (STDs) such as HIV, gonorrhea, or chlamydia. Additional protective measures should be taken to prevent the transmission of these infections.

Proper Usage and Administration of Levonorgestrel-Ethinyl Estradiol

Correct usage of Levonorgestrel-Ethinyl Estradiol is essential for its effectiveness. Here are the key points to remember:

  1. Take the medication orally, once daily, at the same time each day.
  2. Choose a convenient time that you can easily remember.
  3. Follow the package instructions carefully, starting with the first tablet in the pack.
  4. Take the pills in the correct order without skipping any doses.

Are you experiencing stomach upset or nausea with the medication? Taking it after your evening meal or at bedtime may help alleviate these symptoms. However, consistency in timing is crucial – ensure you take the pill at the same time every day, 24 hours apart, regardless of when you choose to take it.

Starting Your First Pack

For those new to this medication, follow these guidelines:

  • Begin taking the medication on the first Sunday following the start of your menstrual period.
  • If your period begins on a Sunday, start the medication on that day.
  • Use additional non-hormonal birth control (e.g., condoms, spermicide) for the first 7 days to ensure protection.
  • If you start on the first day of your period, additional birth control is not necessary for the first week.

Understanding Your Pill Pack

The typical pill pack contains:

  • 84 active pills (with hormones)
  • 7 inactive pills (without hormones)

Take one active pill daily for 84 consecutive days, followed by one inactive pill daily for 7 days. You should expect your period during the week you’re taking the inactive pills. After completing the inactive pills, start a new pack immediately, regardless of whether your period has ended.

Common Side Effects and What to Expect

While Levonorgestrel-Ethinyl Estradiol is generally well-tolerated, some users may experience side effects. Common side effects include:

  • Nausea
  • Vomiting
  • Headache
  • Bloating
  • Breast tenderness
  • Swelling of ankles/feet (fluid retention)
  • Weight changes
  • Vaginal bleeding between periods (spotting), especially in the first few months

Is spotting normal while taking this medication? Yes, some vaginal bleeding or spotting between periods is common, particularly during the initial months of use. However, if these effects persist or worsen, it’s important to consult your healthcare provider promptly.

Serious Side Effects: When to Seek Medical Attention

While rare, some users may experience more serious side effects that require immediate medical attention. These include:

  • Lumps in the breast
  • Mental/mood changes (such as new or worsening depression)
  • Severe stomach or abdominal pain
  • Unusual changes in vaginal bleeding (continuous spotting, sudden heavy bleeding, missed periods)
  • Dark urine
  • Yellowing of eyes/skin
  • Signs of a blood clot (such as sudden severe headache, chest pain, trouble breathing, calf pain/swelling, sudden vision changes)

Can this medication affect blood pressure? Yes, Levonorgestrel-Ethinyl Estradiol may raise blood pressure in some users. Regular blood pressure monitoring is recommended, and any high readings should be reported to your doctor.

Special Considerations and Precautions

Certain factors may affect the use of Levonorgestrel-Ethinyl Estradiol or require special precautions:

  • Smoking, especially if over 35 years old
  • History of blood clots or certain cancers
  • Liver disease
  • Uncontrolled high blood pressure
  • Certain heart problems
  • Diabetes with complications
  • Severe migraines with aura

Should you disclose your full medical history to your doctor before starting this medication? Absolutely. A comprehensive discussion of your medical history, current medications, and any existing health conditions is crucial for determining if Levonorgestrel-Ethinyl Estradiol is the right choice for you.

Interactions with Other Medications and Substances

Levonorgestrel-Ethinyl Estradiol can interact with various medications and substances, potentially affecting its effectiveness or increasing the risk of side effects. Some notable interactions include:

  • Certain antibiotics (e.g., rifampin)
  • Antifungal medications (e.g., griseofulvin)
  • HIV medications
  • Anti-seizure drugs
  • St. John’s Wort
  • Some medications used to treat chronic hepatitis C

Do over-the-counter medications interact with this birth control? While most OTC medications are safe to use with Levonorgestrel-Ethinyl Estradiol, it’s always best to consult with your healthcare provider or pharmacist before combining medications.

Managing Missed Doses and Ensuring Continued Protection

Missing doses of Levonorgestrel-Ethinyl Estradiol can significantly reduce its effectiveness as a contraceptive. Here’s what to do if you miss a dose:

  • If you’re less than 24 hours late: Take the missed pill as soon as you remember, then continue with your regular schedule.
  • If you’re more than 24 hours late: Refer to the Patient Information Leaflet for specific instructions, as they may vary depending on which week of the pill pack you’re in.
  • If you miss two or more pills: Additional contraceptive measures may be necessary, and you should consult the leaflet or your healthcare provider for guidance.

Is it necessary to use backup contraception after missing a pill? In many cases, yes. Especially if you’ve missed more than one pill or are in the first or third week of your pill pack, using a backup method like condoms for 7 days is recommended.

Vomiting and Diarrhea: Impact on Effectiveness

Severe vomiting or diarrhea can potentially reduce the effectiveness of oral contraceptives. If you experience these symptoms:

  1. Continue taking your pills as scheduled if possible.
  2. Use a backup method of birth control (e.g., condoms) until you’ve taken active pills for 7 consecutive days after recovering from the illness.
  3. If your illness occurs in the last week of active pills (days 78-84), skip the inactive pills and start a new pack immediately.

Should you consult your healthcare provider if you experience prolonged vomiting or diarrhea while on this medication? Yes, especially if the symptoms persist for more than 24 hours, as they may advise additional contraceptive measures or alternative treatments.

Long-Term Use and Health Considerations

While Levonorgestrel-Ethinyl Estradiol is generally safe for long-term use, regular check-ups with your healthcare provider are essential. These visits allow for:

  • Monitoring of blood pressure and other vital signs
  • Discussion of any side effects or concerns
  • Evaluation of overall health and any changes in medical history
  • Consideration of alternative contraceptive methods if necessary

Does long-term use of this medication increase cancer risk? The relationship between oral contraceptives and cancer is complex. While some studies suggest a slight increase in breast cancer risk, others indicate a decreased risk of ovarian and endometrial cancers. Your healthcare provider can help you weigh the risks and benefits based on your individual health profile.

Fertility After Discontinuation

Many women wonder about their fertility after stopping Levonorgestrel-Ethinyl Estradiol. Here are some key points:

  • Fertility typically returns quickly after discontinuing the medication.
  • Some women may experience a temporary delay in ovulation.
  • If you don’t wish to become pregnant immediately after stopping, use an alternative form of contraception.

How long should you wait before trying to conceive after stopping this medication? While it’s possible to conceive immediately after discontinuation, some healthcare providers recommend waiting for one normal menstrual cycle before trying to get pregnant. This can help with more accurate dating of the pregnancy.

Alternatives to Levonorgestrel-Ethinyl Estradiol

While Levonorgestrel-Ethinyl Estradiol is an effective and popular choice for contraception, it’s not suitable for everyone. Alternative options include:

  • Other oral contraceptives with different hormone combinations
  • Progestin-only pills (“mini-pills”)
  • Intrauterine devices (IUDs)
  • Contraceptive implants
  • Contraceptive injections
  • Barrier methods (condoms, diaphragms)
  • Natural family planning methods

How do you determine which contraceptive method is best for you? The choice of contraception is highly individual and depends on factors such as medical history, lifestyle, personal preferences, and future pregnancy plans. A thorough discussion with your healthcare provider can help you make an informed decision.

Non-Contraceptive Uses

Beyond contraception, Levonorgestrel-Ethinyl Estradiol may be prescribed for other medical reasons, including:

  • Management of heavy or painful periods
  • Treatment of endometriosis
  • Regulation of irregular menstrual cycles
  • Management of polycystic ovary syndrome (PCOS) symptoms
  • Reduction of acne

Can this medication be used for emergency contraception? While Levonorgestrel-Ethinyl Estradiol is not typically used for emergency contraception, other formulations containing levonorgestrel alone are available for this purpose. It’s important to consult a healthcare provider or pharmacist for appropriate emergency contraception options.