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What is the best muscle relaxer?

So, you sprained your lower back shooting hoops, a stressful work week spurred on a series of tension headaches, arthritis has you waking up with stiffness and neck pain. Now what? Tense, aching muscles can be frustrating, distracting, and throw a wrench into your schedule. When muscle pain hits, it can have you looking for fast-acting relief so you can get on with life. Whether you experience back pain, muscle spasms, arthritis, or injury-related chronic pain, muscle relaxers offer fast pain relief, allowing your body to function as usual. Consider this guide your roadmap to the top muscle relaxers on the market.

What is the best muscle relaxer?

It’s difficult to declare one muscle relaxant better than all others because each type has its own advantages and uses. In general, pain relief treatments fall into one of three categories: over-the-counter (OTC), prescription, and natural. Determining the best muscle relaxer depends entirely on your specific condition and pain level. When in doubt, consult your healthcare provider.

Over-the-counter remedies: OTC pain relievers are often the first line of defense against pain, inflammation, and tension. They can work wonders for milder conditions like neck and lower back pain. Typically, your doctor might start you out on an OTC medication, and if that doesn’t provide the relief you need, he or she may write a prescription for something higher-grade.

Prescription drugs: For more chronic pain and conditions where OTC medications just won’t cut it, your doctor may prescribe something stronger. Because of their more serious side effects, prescription muscle relaxers are designed for short-term use, after which your doctor will transition to other drugs or treatments.

Natural remedies: For minor soreness and stress-related symptoms, the only treatment you need might be drawn straight from nature. Before rushing off to the doctor for an examination and potential prescription, you might be able to administer an effective plant-based therapy right from home.

What is the best over-the-counter (OTC) medicine for muscle pain?

These are the medications that you can find while perusing the aisles at your local pharmacy or convenience store. Most of them are household names, and it’s not uncommon to keep them on hand, stashed in a medicine cabinet, just in case. Even though OTC medications are easy to obtain, they’ll do the job for many aches and pains, and doctors often recommend them prior to prescribing stronger treatment options.

“OTC NSAIDs, like ibuprofen and naproxen, are a good first-line agent to decrease inflammation surrounding an injury,” recommends Joanna Lewis, Pharm.D., creator of The Pharmacist’s Guide. They might not have the same potency of high-grade muscle relaxants, but they’re still effective and have very few side effects. If you roll your ankle at the gym or wake up with back pain, try one of these before asking your doctor for a prescription.

  1. Advil (ibuprofen): This is a staple of parents, doctors, and athletes alike. Ibuprofen is one of the most widely used nonsteroidal anti-inflammatory drugs (NSAIDs) available. As such, Advil doesn’t just remedy pain, but also inflammation as well. It’s highly versatile. Use it to treat low back pain, osteoarthritis, menstrual cramps, fever, headaches, migraines, sprains, and other minor injuries. Low doses are available over the counter, but a doctor can prescribe higher doses as well.
  2. Motrin IB (ibuprofen): Don’t be fooled by the different brand name. Motrin IB and Advil are the same drug. Therefore, they shouldn’t be taken together, as it could increase the risk of overdose.
  3. Aleve (naproxen): Another medicine cabinet staple, naproxen is similar to ibuprofen in many ways. It’s also an NSAID, so it works by reducing inflammation. It’s useful in treating muscle pain, headaches, migraines, osteoarthritis, fever, cramps, and minor injuries. The main difference between naproxen and ibuprofen is their dosing. You can take naproxen every eight to 12 hours and ibuprofen every four to six, so Aleve is slightly longer-lasting.
  4. Aspirin: One more NSAID for you. Aspirin treats many of the same conditions, relieving pain and reducing inflammation. However, daily doses of aspirin have been proven effective at reducing the risk of blood clots, strokes, and heart attacks in some people. Ask your doctor before using for clot prevention. If you’re a candidate, you will likely take a “baby” aspirin, or 81 mg, coated tablet daily. Common brand names include Bayer or Ecotrin.
  5. Tylenol (acetaminophen): Unlike NSAIDs, acetaminophen focuses solely on treating pain—not inflammation. It’s used for muscle aches, headaches, migraines, back and neck pain, fevers, etc. However, if swelling and inflammation is the underlying cause of your pain, acetaminophen will not be nearly as effective as NSAIDs like those listed above. Acetaminophen’s wide range of uses and relatively few side effects make it the most popular OTC pain reliever worldwide.

RELATED: About Advil | About Morin IB | About Aleve | About Aspirin | About Tylenol

What are the best prescription muscle relaxers?

There are certain times when over-the-counter medications simply aren’t enough. If you’ve been taking acetaminophen or ibuprofen consistently but are still dealing with back pain, spasms, or other issues, it might be time for something more robust. In cases like these, doctors may look to prescription muscle relaxants as a more effective, albeit temporary, answer.

“A pulled back muscle or neck pain may require a doctor’s visit or other diagnostic tests to get to the heart of the issue,” Dr. Lewis says. “There are several good prescription medications like methocarbamol, cyclobenzaprine, and metaxalone.”

Recent studies have shown that skeletal muscle relaxants (SMRs), or antispasmodics, outperform anti-inflammatory drugs (NSAIDs), like ibuprofen and acetaminophen, in relieving severe pain associated with conditions like acute back pain. On the flip side, they also have potentially more serious side effects and shouldn’t be used for long-term pain management. Even so, these prescription drugs are effective and reliable options for short-term pain relief:

  1. Flexeril or Amrix (cyclobenzaprine): Cyclobenzaprine is a popular and relatively inexpensive generic muscle relaxant often used short-term to treat muscle spasms and pain related to sprains, strains, etc. A typical dose is 5 to 10 mg at bedtime for two to three weeks, although your doctor might approve up to 30 mg daily (taken as one 5 or 10 mg tablet every eight hours) if your case is more severe. Side effects include drowsiness, dry mouth, dizziness, and fatigue.
  2. Robaxin (methocarbamol): Commonly used to treat severe muscle spasms, back pain, and occasionally tetanus spasms, methocarbamol is administered orally in up to 1500 mg doses or intravenously in 10 ml of 1000 mg. This dosing is usually higher in the first 48 to 72 hours, then decreased. Patients may experience drowsiness, dizziness, blurred vision and—in intravenous doses—reactions at the injection site. However, it’s generally less of a sedative than most other muscle relaxants.
  3. Skelaxin (metaxalone): While it’s slightly more expensive than other SMRs, like methocarbamol, the upside of metaxalone is that it delivers the same effectiveness with a relatively low rate of side effects. In three to four 800 mg doses per day, it acts on your central nervous system (brain and spinal cord) and may cause drowsiness, dizziness, irritability, and nausea, but metaxalone doesn’t sedate as heavily as the alternatives.
  4. Soma (carisoprodol): Similar to Robaxin, Soma is generally used to treat pain associated with acute musculoskeletal conditions. Carisoprodol acts on the central nervous system to intercept neurotransmitters relayed between the nerves and brain. It’s administered in 250-350 mg doses three times per day (and at bedtime) for up to three weeks. Common side effects include drowsiness, dizziness, and headaches. It has also been associated with addiction, so it should be used with caution.
  5. Valium (diazepam): Most often, you’ll hear about Valium as a treatment for anxiety disorders and alcohol withdrawal symptoms, but it can also be an effective medication for muscle spasms. Diazepam is a benzodiazepine (like Xanax) that decreases the sensitivity of certain brain receptors. Dosage varies depending on the condition, but for skeletal muscle spasms, it’s typically 2-10 mg, three or four times per day. Because it slows down brain activity, Valium frequently causes fatigue and muscle weakness so, like other muscle relaxants, you shouldn’t combine it with alcohol or other drugs.
  6. Lioresal (baclofen): Unlike the muscle relaxants above it on this list, baclofen is primarily used to treat spasticity (continuous muscle tightness or stiffness) caused by multiple sclerosis or spinal cord injury. It is given as an oral tablet, or can be injected into the spinal theca. Most often, baclofen is prescribed on a schedule that increases the dosage gradually every three days. It can cause sleepiness, dizziness, nausea, hypotension (low blood pressure), headache, convulsions, and hypotonia (weak muscle tone), so even though it’s effective for spasticity treatment, it might not be the best option for pain relief.
  7. Lorzone (chlorzoxazone): This is yet another SMR that acts on the central nervous system to treat the pain and spasms associated with muscle and bone conditions. It’s fairly well-tolerated despite occasional drowsiness, dizziness, lightheadedness, and malaise. In rare cases, it can cause gastrointestinal bleeding, so doctors will often opt for other medications. Typical dosage is 250 to 750 mg three or four times daily.
  8. Dantrium (dantrolene): Similar to baclofen, dantrolene is primarily used to treat spasticity. It’s effective for spasms associated with spinal cord injury, stroke, cerebral palsy, or multiple sclerosis, and is also sometimes used for malignant hyperthermia. Common side effects include diarrhea, drowsiness, dizziness, fatigue, and muscle weakness. The starting dosage is 25 mg daily and it can be increased slowly if needed, up to 100 mg three times daily. In rare cases of overuse or long-term use, it has been attributed to liver damage.
  9. Norflex (orphenadrine): In addition to treating injury-related pain and spasms, orphenadrine is also effective in relieving the trembling from Parkinson’s disease. Some patients may experience dry mouth along with heart palpitations, blurred vision, weakness, nausea, headache, dizziness, constipation, and drowsiness, but usually only with increased dosages. However, this muscle relaxant can sometimes cause anaphylaxis, a type of severe allergic reaction. So, for basic muscle pain, doctors often go with one of the other options on this list. Standard dosing is 100 mg, twice per day.
  10. Zanaflex (tizanidine): Tizanidine is primarily used to treat stiffness and spasms associated with multiple sclerosis and cerebral palsy, similar to baclofen. Both show effectiveness, although tizanidine sometimes shows fewer side effects, which can include dry mouth, tiredness, weakness, dizziness. It’s administered in 2 or 4 mg doses.

RELATED: Amrix details | Robaxin details | Skelaxin details | Soma details | Valium details | Lioresal details | Lorzone details | Dantrium details | Orphenadrine details | Zanaflex details

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What is the best natural muscle relaxer?

Let’s say your pain is lifestyle-related. Maybe a new workout routine put you through the wringer, or slouching over your laptop has started to take its toll on your back and neck. Minor soreness or aches happen all the time for any number of reasons, and they might not be severe or chronic enough to warrant muscle relaxers or other pain relievers. The good news is that there are plenty of natural remedies and dietary solutions to mild body pain. Even better is that you can find most of these treatments in food and supplements.

Dr. Lewis considers certain natural remedies ideal for stress management or to supplement other treatments. “Lavender oil and chamomile are great ingredients for relaxation when taking a bath or getting ready for bed,” she says. “They aren’t usually a first-line treatment but are great in conjunction with other things to manage tension from stress.”

CBD oil (cannabidiol) has been a popular but widely-debated natural supplement. Extracted from the hemp plant, it doesn’t cause a “high,” but it can be effective in treating epilepsy, anxiety, and general pain, among other ailments. Many swear by it for a broad scope of conditions, but research is currently ongoing as to what else it can do.

Additionally, the Food and Drug Administration (FDA) has only approved one CBD product, Epidiolex, which may be prescribed to treat two rare forms of epilepsy. “Many [CBD products] are not regulated, [so] the effectiveness between products is not consistent,” Dr. Lewis explains.

Or, you may have heard of arnica gel, made from an herb native to central Europe. It’s commonly used to treat injury-related pain and swelling and arthritis. Like CBD, there isn’t extensive research on it yet, but arnica has shown promise as a natural pain remedy.

Going the natural route? These natural muscle relaxants can promote pain-free living and holistic health:

Chamomile tea Oral Anxiety, inflammation, insomnia
CBD oil Oral, topical Epilepsy, anxiety, chronic pain
Arnica gel Topical Osteoarthritis, muscle aches/soreness
Cayenne pepper Oral, topical Stomach pain, joint pain, heart conditions, cramps
Lavender oil Topical Anxiety, insomnia, general pain relief
Magnesium Oral Muscle cramps, indigestion, constipation
Lemongrass Oral, topical Stomach ache, digestive tract spasms, rheumatoid arthritis
Turmeric Oral Osteoarthritis, indigestion, abdominal pain
Massage, physical therapy Topical Muscle pain, soreness, stress, anxiety

While this list isn’t exhaustive, it presents you with plenty of options, no matter what has you hurting. As always, consult your healthcare provider for professional medical advice before taking a new medication. Even natural treatments can cause serious drug-drug interactions.

Muscle Relaxants for Back Pain and Neck Pain

Muscle relaxants are medications that help reduce muscle spasms, which are involuntary muscle contractions caused by a spine-related problem, such as whiplash, fibromyalgia, or low back strain. Often, muscle spasms cause severe pain and may limit your mobility.

Your doctor may prescribe a muscle relaxant to ease muscle spasms, reduce pain, and help your muscles move better. When your muscles move better, it makes other spine pain treatments, such as physical therapy, stretching, and exercise, more effective.
Spasms are localized and occur because of a musculoskeletal issue. Photo Source: 123RF.com.

Muscle relaxants treat two conditions: spasticity and spasm. Spasticity is marked by long-term muscle contraction caused by a brain or spinal cord injury. Spasms, on the other hand, are localized and occur because of a musculoskeletal issue.

Prescription muscle relaxants fall into 2 groups: antispastics and antispasmodics.

  • Antispastics are prescribed to treat spasticity caused by neurological disorders, such as cerebral palsy or spinal cord injury.
  • Antispasmodics are used to treat occasional muscle spasms.

While some antispasmodics may treat spasticity in addition to spasms, antispastics should not be used to treat spasms.

Muscle Relaxants for Muscle Spasms

Muscle spasms are painful and may restrict mobility, which can limit your ability to perform even basic activities. Painful, tight muscles can also interfere with getting a good night’s sleep.

If your muscle pain persists, your doctor may prescribe a muscle relaxant in addition to your pain medication. Find the medicine you’ve been prescribed on one of the two lists below.

Below are common antispasmodics (the generic names are listed first, with a brand name example in parentheses).  Remember, these medications generally treat acute muscle spasms. If you’ve been diagnosed with a neurological disorder that causes spasticity, look for your medication on the list of antispastics:

Carisoprodol (Soma)

Carisoprodol is a centrally acting muscle relaxant. It is indicated for adults and teens age 16 or older. Carisoprodol comes in tablet form in dosages of 250 to 350 mg. Typical instructions are to take it three times a day and at bedtime. Carisoprodol can be habit forming and should only be used for two to three weeks.  

Chlorzoxazone (Lorzone, Parafon Forte DSC, Remular-S)

Chlorzoxazone is a skeletal muscle relaxant useful for treating acute muscle strains, including in the back. It comes in tablet form, and a typical dose for adults is 500 mg three or four times a day. One of the side effects associated with chlorzoxazone is red or purple urine. This is due to the way your body metabolizes the drug and is not a cause for concern.                      

Cyclobenzaprine (Amrix)

Cyclobenzaprine is another skeletal muscle relaxant. It comes as a tablet, suspension, or extended release capsule. Cyclobenzaprine should not be used by people who have certain heart conditions such as heart failure, a recent heart attack, or forms of arrythmia.

Metaxalone (Skelaxin)

Metaxalone is a centrally acting muscle relaxer, usually given in tablet form, 800 mg three to four times a day. Although drowsiness, irritability, and stomach or bowel upset are the most common side effects, metaxalone carries a long list of less common potential side effects, according to Mayo Clinic. 

Methocarbamol (Robaxin)

Like the other medications in this section, methocarbamol is a centrally acting skeletal muscle relxant. A total of 1500mg a day, split up into three 500mg tablets or two 750mg tablets, is a standard dose. It has a fairly long list of potential side effects, so it is important to only take this and other muscle relaxants as directed by your doctor.

Orphenadrine (Norflex)

Orphenadrine is both a muscle relaxant and an anticholinergic—a drug that blocks the neurotransmitter acetylcholine. Because of its anticholinergic properties, orphenadrine is often used to control tremors caused by Parkinson’s disease. A typical dose is 200mg to 250mg total, taken two or three times a day. 

You are more likely to be prescribed an antispastic if your muscle spasticity is due to a neurological condition such as a spinal cord injury. These drugs are not typically used to treat the occasional muscle spasm.

Baclofen (Ozobax)

Baclofen, like the next drug on this list, is used for chronic neurogenic conditions that cause spasticity, such as multiple sclerosis or spinal cord injuries. Medication on the previous list—antispasmodics—are more appropriate for acute muscle spasms. 

Tizanidine (Zaniflex)

This skeletal muscle relaxant is often used to treat muscle spasms caused by multiple sclerosis, an autoimmune condition that attacks the fatty, insulating myelin sheaths that encase part of your nerve cells (and a close cousin of transverse myelitis). 

Sometimes doctors and researchers discover new uses for existing medications. These so-called off-label uses need time and testing to make it into the official FDA-approved list of uses. The following medications are not antispastics or antispasmodics, but can still help some people with spasticity and muscle spasms.


Benzodiazepines (often abbreviated as “benzos”) such as oxazepam and diazepam (Valium) are sedatives that are usually used as anti-anxiety medications but can often treat back pain and muscle spasms. Researchers believe these drugs work by tamping down on nerve activity by modifying a neurotransmitter.

Common benzodiazepines include:

·         Alprazolam (Xanax)

·         Clonazepam (Klonopin)

·         Lorazepam (Ativan)

Because they’re sedatives, the most common side effects are:

·         Drowsiness

·         Dizziness

·         Weakness

·         Balance trouble

Benzodiazepines are also addictive and carry the risk of overdose. Be sure to take them only and exactly as your doctor indicates.


Clonidine, sold under the brand names Catapres and Kapvay, usually treat attention deficit hyperactivity disorder (ADHD) and high blood pressure. Clonidine may react strongly with alcohol and can cause a host of side effects, including:

·         Dry mouth

·         Fatigue

·         Nausea

·         Headache

·         Rash

·         Hives

·         Difficulty swallowing or breathing

…and others.  


Gabapentin (Gralise, Horizant, Neurontin) is an anticonvulsant medication effective at controlling epileptic seizures and restless legs syndrome. It is also frequently used to treat nerve pain and muscle spasticity. Gabapentin can cause many side effects—some severe—such as:

·         Drowsiness

·         Fatigue

·         Headache

·         Vision trouble

·         Cognitive issues

·         Vomiting

·         Bowel changes

·         Weight gain

Difficulty breathing

Muscle relaxants may help reduce pain, and improve movement and range of motion, but your doctor will likely recommend that you first try acetaminophen or a nonsteroidal anti-inflammatory drug (NSAID). In some cases, these over-the-counter medications will be enough to help alleviate your pain.


NSAIDs are some of the most common OTC medications for pain in general. This class of drugs include:

  • Aspirin (Bayer, Excedrin)
  • Ibuprofen (Motrin, Advil)
  • Naproxen (Aleve)

Side effects are generally mild and can include upset stomach, diarrhea, and gas. NSAIDs may increase the risk of bleeding when combined with some medications such as blood thinners and selective serotonin reuptake inhibitors (SSRIs), which are antidepressants.


Sold under the brand name Tylenol (among others), acetaminophen is another popular choice for over-the-counter pain relievers. It often has fewer side effects than NSAIDs but won’t relieve inflammation.

Habit Formation

Muscle relaxants for acute back or neck pain are usually prescribed to relieve short-term muscle pain—and some can be habit-forming. For these reasons, most doctors will write prescriptions with less than 2 weeks’ worth of medication. To reduce your risk of dependency or abuse, use your medication exactly as your doctor prescribes.

Drowsiness and Dizziness

The most common side effects associated with muscle relaxants are drowsiness and dizziness. This is because muscle relaxants depress your central nervous system, making you less alert and attentive. As such, avoid alcohol and don’t perform tasks that require your complete attention, such as operating machinery or driving, while taking a muscle relaxant.

Drug Interactions

Muscle relaxants pose health risks when they are taken with certain medications and supplements, including but not limited to:

  • Opioids
  • Sleep aid medications
  • St. John’s wort

Make sure your doctor knows every medication and supplement you are taking before starting muscle relaxant therapy.

Muscle spasms are one of the more likely back pain causes to spontaneously resolve—that is, go away on their own—in two weeks or so. Talk to your primary care provider or spine specialist if your pain lasts for longer than two weeks.

Other situations in which you may want your physician’s opinion include:

  • New incidence of spasticity, especially if you don’t know what’s causing it
  • Spasticity that has become more severe or more frequent
  • Severe and frequent muscle spasms
  • Having side effects from your muscle relaxant
  • Frozen joints due to muscle contractions limiting range of motion

If your muscle pain doesn’t respond to over-the-counter medications, then muscle relaxants may be a good treatment option to alleviate your muscle spasms. For best results, muscle relaxants should be viewed as part of a treatment plan that may include gentle stretching, physical therapy, and exercise—not the sole treatment. As always, don’t hesitate to discuss your medications and comprehensive spine health plan with your doctor. A solid understanding of your therapeutic options is a strong defense against back pain.

Prescription And Over The Counter Muscle Relaxers

Prescription Muscle Relaxers

Muscle relaxers are drugs that relax muscle spasms. As a result, skeletal muscle tone decrease. A person feels stiffness and sluggishness in movements with the overall reduction in muscle activity. Initially, muscle relaxants were only used by anesthesiologists to relieve muscle spasms during surgery. Now the medications are widely used in other areas of medicine and cosmetology. 

Muscle relaxants work by acting on the body’s central nervous system. They do not heal muscles, which can treat themselves, but relieve the pain allowing the body time to heal itself. 

You cannot buy muscle relaxants over the counter in the United States. As with most medications, they are available only by prescription. 

Most muscle relaxants come in tablet form. 

Some examples of common muscle relaxers are: 

  • carisoprodol (Soma)
  • chlorzoxazone (Parafon Forte DSC)
  • cyclobenzaprine (Flexeril)
  • metaxalone (Skelaxin)
  • methocarbamol (Robaxin)
  • and tizanidine (Zanaflex)

Precautions When Taking Muscle Relaxants

When talking about a muscle relaxant, doctors warn patients of several precautions. First, the drugs relieve pain, which helps you feel healthy and go back to your everyday life. 

However, if you do it before you completely heal your, it can make the injury worse. Taking a few days off from your normal activities is probably wise. 

In any case, it’s always best to check with your doctor if you’ve any questions.

Muscle relaxants will only help with muscle pain. Avoid taking this type of drugs with any other types of pain. 

Patients taking muscle relaxants should avoid driving, operating machinery or anything that could be harmful. 

This precaution is important because some people may feel drowsy, dizzy, confused and light-headed while taking these medications. 

Other side effects of most muscle relaxers include blurred vision, clumsiness and unsteadiness due to the medication’s interaction with the central nervous system.

Muscle relaxants may also add the effects of alcohol and other drugs, which slow down the central nervous system. These drugs include antihistamines, cold medicines, allergy medicine, sleep aids, tranquillizers, medicines for seizures, and similar drugs. Make sure to check with your physician before taking any of the above. 

People with diabetes should be aware that an ingredient in muscle relaxants could cause false test results on one type of sugar test in the urine.

Patients should always consult with a doctor before taking a muscle relaxant and let them know about preexisting conditions. Previous heart attacks or conditions, kidney disease, hepatitis, history of drug abuse and pregnancy are just a few things you should check with your doctor before taking a muscle relaxant. 

For example, some muscle relaxers can pass into breast milk and upset or harm a nursing child.

Despite the side effects and cautionary measures, muscle relaxers are usually help alleviate pain.

Soma (Carisoprodol)

Soma, which is the more common name for carisoprodol, is a muscle relaxer. Combined with other muscle-relaxing measures such as rest and physical therapy, Soma can relieve the pain and discomfort caused by sprains, strains and other muscle injuries. 

This drug can also be used as a treatment option for people with fibromyalgia.

Taken by mouth, Soma blocks pain sensations between the nerves and brain. 

Carisoprodol may become habit-forming. Do not share the medication with other people. 

Doctors generally -prescribe the drug to individuals with a history of drug abuse and/or addiction.

People allergic to Carisoprodol or meprobamate (Equanil, Miltown) should avoid taking the drug. Individuals with porphyria, an abnormality in heme production, should also avoid taking the drug. Heme is an important bodily substance that is usually found in the blood and bone marrow.

Approved by the FDA for usage in 1959, Soma is not as commonly prescribed as newer muscle relaxants. 

Besides the fact that it can be addictive, the medication has a strong, generalized sedative effect. You should not drive or operate heavy machinery while under the influence of this medication, especially until you know how it affects you. 

Soma is not a good fit for patients with a prior history of seizure disorders such as epilepsy, liver and/or kidney disease. 

It can interact negatively with medications for allergies, coughs, colds, and other muscle relaxers, sedatives, tranquillizers, and certain vitamins. 

Make sure to let your doctor know about all over the counter and prescription medications you are already taking.

Soma is not recommended for pregnant women and/or nursing mothers. It is unknown whether the medication can pass through breast milk or harm an unborn fetus or a nursing baby. 

Doctors do not prescribe carisoprodol to a child younger than 12 years old. 

Take carisoprodol with milk or food as it can cause nausea and stomach upset. 

Other side effects of som include:

  • Drowsiness
  • Dizziness
  • Clumsiness
  • Headache
  • Heart palpitations (increased heart rate)
  • Vomiting
  • Skin rash

If any of the following symptoms occur, call your doctor immediately:

  • Difficult breathing
  • Fever
  • Weakness
  • Burning in the eyes

Flexeril (Cyclobenzaprine) 

Flexeril, a generic brand of cyclobenzaprine, is prescribed as a muscle relaxant. The medication alleviates muscle spasms caused by the muscles themselves (not the nerves surrounding them). 

In combination with rest and – as needed – physical therapy, cyclobenzaprine is very effective. 

Generally used in the short-term (about 2-3 weeks), Flexeril has had some success long-term in treating generalized pain disorders such as Fibromyalgia and Chronic Fatigue Syndrome. 

Take Flexeril at night, unless otherwise is prescribed, as it can make you drowsy. 

Usually, doctors prescribe a dose of 5 -10 mg of cyclobenzaprine. 

Chemically related to tricyclic antidepressants (Elavil, Endep, Tofranil), Flexeril does not alleviate the symptoms of depression. If you are currently taking antidepressants or have done so within the last two weeks before being prescribed this medication, it’s wise to alert your doctor. 

Cyclobenzaprine can negatively interact with Monoamine Oxidase Inhibitors (Marplan, Nardil, Parnate), anti-seizure medications, sedatives, sleeping pills, tranquillizers, certain vitamins and some remedies, both over the counter and prescription, for coughs, colds and allergies.

People who have hyperactive thyroids, heart disease, especially those who recently suffered a heart attack, glaucoma and difficulty urinating, are not encouraged to take this medication. 

Flexeril is not expected to harm a fetus, but if you are pregnant or plan to become pregnant, alert your doctor.

Do not use cyclobenzaprine if you are breastfeeding without checking with your doctor first. 

This medication is not recommended for individuals over 65 either.

Common side effects of Flexeril include:

  • dry mouth or throat
  • blurry vision
  • drowsiness
  • dizziness
  • fatigue
  • loss of appetite
  • stomach pain
  • nausea
  • diarrhoea
  • constipation
  • muscle weakness.

Some side effects are not normal and indicate a serious problem, such as an allergy to cyclobenzaprine. If you experience any of these symptoms after taking the medication, call your doctor immediately.

The following symptoms could become life-threatening. Seek immediate medical help if you are experiencing one or several of them:

  • rapid or pounding heartbeat
  • chest pain or tightness
  • pain spreading to upper arm or shoulder
  • unusual numbness and/or weakness, especially if only on one side of the body
  • sudden headache
  • sudden confusion, vision problems, speech and/or balance
  • fainting
  • light-headedness
  • jaundice
  • low-grade fever
  • dark urine
  • clay-coloured stools
  • seizure and/or convulsions
  • hallucinations
  • unusual thoughts or behaviour
  • bruising easily
  • inexplicable bleeding
  • hives
  • difficulty breathing
  • facial swelling
  • and swollen lips, tongue or throat.

Skelaxin (metaxalone)

Skelaxin (metaxalone) is a muscle relaxant used in conjunction with other measures such as rest, physical therapy. It relieves discomfort associated with acute musculoskeletal conditions such as pain and injury as well as muscle spasms.  

The recommended dosage for Skelaxim in adults and children over twelve years of age is one 800 mg tablet 3-4 times per day. 

Metaxalone provides prompt relief, usually within one hour of taking the medication. 

It is not habit-forming and provides an improved range of motion. 

The medication also does not interfere with posture and balance. Skelaxin provides minimal sedation. That is why you only have a small chance of feeling dizzy or sleepy while taking it. 

There are also no adverse cardiovascular effects to the medication, making it a commonly prescribed muscle relaxant. 

As a result, there are very few side effects of this drug. The most common include nausea and vomiting. Other side effects are: 

  • drowsiness,
  • dizziness,
  • headache,
  • nervousness,
  • irritability,
  • rash,
  • jaundice
  • anemia (in rare instances).

It is strongly suggested that you don’t take Skelaxin with alcohol or barbiturates as these could interact negatively.  

This medication can impair your ability to drive. 

Before taking this drug, let your doctor know if you have any liver problems, as metaxalone can impact it negatively. 

Provide your doctor with a list of all prescription, over the counter and herbal substances you are taking so that he/she can determine if there are any risks. 

If you plan to become or are currently pregnant or breastfeeding, please alert your doctor because Skelaxin can affect an unborn or newborn child. 

Zanaflex (Tizanidine)

Zanaflex, also known as tizanidine generically, is a muscle relaxant. It is used for various muscular-related conditions, including muscle tightness, cramps, spasms and more. 

A prescription medication, tizanidine, may help alleviate the symptoms of multiple sclerosis and spinal cord injuries. Zanaflex works by blocking nerve signals from the spine to the brain, which helps relieve muscle pain.

Tizanidine can be habit-forming. Thus, you should be careful to take it exactly as prescribed. 

Start taking the drug at a low dose and slowly move up to a higher level to keep certain side effects such as dizziness or drowsiness at bay. (Make sure you get a clear schedule from your doctor and adhere to it.)

Zanaflex usually begins working within 1-2 hours of taking it. The effects wear off about 6 hours later (maybe a little less.) 

You should not take more than 36 milligrams of this medication a day. Follow your doctor’s instructions, and don’t take more than is prescribed.

Your body’s absorption of the medication depends upon whether you take it as a capsule or pill and on whether you take the meds on an empty stomach or not. You may even sprinkle a capsule’s contents over food.

If used in high doses or regularly, Zanaflex may cause dependence. If you decide to stop using the medication abruptly, then you will go into withdrawal. Reactions include: 

  • anxiety
  • tremor
  • increased blood pressure
  • higher than normal heart rate
  • muscle tension, etc.  

If you struggle with any of these symptoms, contact your doctor immediately. 

Over The Counter Muscle Relaxers

In most cases, it is not possible to get muscle relaxants over the counter in the US. You need to have a medical prescription from your doctor to buy these medications. 

Your doctor may suggest you try over the counter NSAID’s medications or acetaminophen if you are suffering from moderate pain. And if they fail to help, prescribe more potent painkillers or muscle relaxers. 

Natural Muscle Relaxers

You can often reduce muscle pain by taking analgesics and rest, but other therapies are required in many cases.

Nowadays, sedentary lifestyles are especially common. In addition to this, stress and daily responsibilities contribute to an unhealthy lifestyle that can cause various discomforts.

Fortunately, in addition to the already known remedies, several natural relaxants have no side effects and help soothe the pain that interferes with normal life.

The following natural muscle relaxers may help you to relieve mild to moderate muscle pain. 


Because of its soothing and anti-inflammatory effects, both valerian oil and liquid valerian are widely used to relieve muscle tension. Its use reduces inflammation and speeds up circulation, which in turn improves oxygenation.

Drink up to two glasses (500 ml) per day. In oil, rub a small amount of valerian oil into the affected muscle area and rest.

As a side note, this herb may cause drowsiness.

Cayenne Pepper

It is widely used at home and is more than effective in quickly and effectively treating pain caused by muscle spasms. 

Although its pungent taste may be unbearable for some of us, cayenne pepper is an excellent remedy for diseases affecting the muscles.

It contains an active ingredient called capsaicin, which provides anti-inflammatory and analgesic effects.

Add small amounts of cayenne pepper to smoothies and tea. Or you can buy cayenne pepper oil and use it to massage tense muscles.


Chamomile is one of the most frequently used plants as an infusion in the world. Its antispasmodic, anti-inflammatory and diuretic effects are well known, especially in treating digestive disorders, menstruation and nerves.

Chamomile is an excellent natural remedy that relieves muscle pain and swelling.

It has antispasmodic and anti-inflammatory properties that help to relax the muscles, especially in stress-induced tension.

Take one cup (250 ml) of chamomile tea 2-3 times a day.

Apply chamomile oil on your palms and rub well into the affected areas.


Blueberries are a great source of antioxidants and polyphenols that have anti-inflammatory effects. One experiment found that blueberry supplements improves athletic performance and reduces inflammation. It helps muscles relax and recover after a workout.

Peppermint Oil

Peppermint oil is one of the natural remedies that help relax muscles when they are overly tense. It has anti-inflammatory and analgesic properties that reduce pain while promoting better blood circulation to help the injured area quickly.

Add a small amount of peppermint oil to the palms of your hands and rub it thoroughly into the affected area where the muscle tension has appeared. Massage for at least 5 minutes to achieve the best result

Cherry Juice

You can prevent muscle pain after a workout by drinking sour cherry juice. It contains antioxidants and anti-inflammatory properties that help relax your muscles.

One study found that tart cherry juice helped runners reduce post-workout pain. Keep in mind that the researchers used a strong cherry concentration.

March, 17, 2021 by Laura Moody RPh

Tip Sheet: Ten Medications Older Adults Should Avoid or Use with Caution



USE WITH CAUTION NonSteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs are used to reduce pain and inflammation.

AVOID regular, long-term use of NSAIDs

  • When good alternatives are not available and NSAIDs are necessary, use a proton pump inhibitor such as omeprazole (Prilosec) or misoprostol (Cytotec) to reduce bleeding risk.
  • Use special caution if you are at higher risk of developing bleeding stomach ulcers. Those at higher risk include people more than 75 years old, people taking oral steroids, and people taking a blood-thinning medication such as apixaban (Eliquis), aspirin, clopidogrel (Plavix), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban (Xarelto), or warfarin (Coumadin).
  • Also use special caution if you have kidney problems or heart failure.
NSAIDs can increase
the risk of bleeding stomach ulcers. They can also increase blood pressure, affect your kidneys, and make heart failure worse.

USE WITH CAUTION Digoxin (Lanoxin)
Digoxin is used to treat heart failure and irregular heartbeats.

  • For most older adults, other medications are safer and more effective.
  • Avoid doses higher than 0.125 mg per day. Higher doses increase toxicity and provide little additional benefit.
  • Be particularly careful if you have moderate or severe kidney problems.
It can be toxic in older adults and people whose kidneys do not work well.

AVOID Certain Diabetes Drugs

  • Glyburide (Diabeta, Micronase) and chlorpropamide (Diabinese)
These can cause dangerously low blood sugar.

AVOID Muscle Relaxants

  • Such as cyclobenzaprine (Flexeril), methocarbamol (Robaxin), carisoprodol (Soma), and similar medications.
They can leave you feeling groggy and confused, increase your risk of falls, and cause constipation, dry mouth, and problems urinating. Plus, there is little evidence that they work well.

AVOID Certain Medications used for Anxiety and/or Insomnia

  • Benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), or chlordiazepoxide (Librium)
  • Sleeping pills such as zaleplon (Sonata), zolpidem (Ambien), and eszopiclone (Lunesta)
They can increase your risk of falls, as well as cause confusion. Because it takes your body a long time to get rid of these drugs, these effects can carry into the day after you take the medication.

AVOID Certain Anticholinergic Drugs

  • Antidepressants amitriptyline (Elavil) and imipramine (Tofranil)
  • Anti-Parkinson drug trihexyphenidyl (Artane)
  • Irritable bowel syndrome drug dicyclomine (Bentyl)
They can cause confusion, constipation, dry mouth, blurry vision, and problems urinating (in men).
AVOID the Pain Reliever Meperidine (Demerol) It can increase the risk of seizures and can cause confusion.

AVOID Certain Over-the-Counter (OTC) Products

  • AVOID products that contain the antihistamines diphenhydramine (Benadryl) and chlorpheniramine (AllerChlor, Chlor-Trimeton). These medications are often included in OTC remedies for coughs, colds, and allergies.
  • AVOID OTC sleep products, like Tylenol PM, which contain antihistamines such as diphenhydramine.
Although these medications are sold without a prescription, they are not risk- free. They can cause confusion, blurred vision, constipation, problems urinating, and dry mouth.

If you are NOT being treated for psychosis, use Antipsychotics WITH CAUTION

  • Such as haloperidol (Haldol), risperidone (Risperdal), or quetiapine (Seroquel). These medications are commonly used to treat behavioral problems in older adults with dementia.
They can increase the risk of stroke or even death in older adults with dementia. They can also cause tremors and other side effects, as well as increase your risk of falls.

AVOID Estrogen pills and patches

  • Typically prescribed for hot flashes and other menopause-related symptoms
They can increase your risk of breast cancer and blood clots.

Medicines for back pain: MedlinePlus Medical Encyclopedia

Acute back pain often goes away on its own over several weeks. In some people, back pain persists. It may not go away completely or it may get more painful at times.

Medicines can also help with your back pain.


Over-the-counter means you can buy them without a prescription.

Most health care providers recommend acetaminophen (such as Tylenol) first because it has fewer side effects than other drugs. Do not take more than 3 grams (3,000 mg) on any one day, or over 24 hours. Overdosing on acetaminophen can cause severe damage to your liver. If you already have liver disease, ask your doctor if acetaminophen is OK for you to take.

If your pain continues, your provider may suggest nonsteroidal anti-inflammatory drugs (NSAIDs). You can buy some NSAIDs, such as ibuprofen and naproxen, without a prescription. NSAIDs help reduce the swelling around the swollen disk or arthritis in the back.

NSAIDs and acetaminophen in high doses, or if taken for a long time, can cause serious side effects. Side effects include stomach pain, ulcers or bleeding, and kidney or liver damage. If side effects occur, stop taking the drug right away and tell your provider.

If you are taking pain relievers for more than a week, tell your provider. You may need to be watched for side effects.


Narcotics, also called opioid pain relievers, are used only for pain that is severe and is not helped by other types of painkillers. They work well for short-term relief. Do not use them for more than 3 to 4 weeks unless instructed by your provider to do so.

Narcotics work by binding to receptors in the brain, which blocks the feeling of pain. These drugs can be abused and are habit-forming. They have been associated with accidental overdose and death. When used carefully and under a provider’s direct care, they can be effective in reducing pain.

Examples of narcotics include:

  • Codeine
  • Fentanyl — available as a patch
  • Hydrocodone
  • Hydromorphone
  • Morphine
  • Oxycodone
  • Tramadol

Possible side effects of these drugs include:

  • Drowsiness
  • Impaired judgment
  • Nausea or vomiting
  • Constipation
  • Itching
  • Slowed breathing
  • Addiction

When taking narcotics, do not drink alcohol, drive, or operate heavy machinery.


Your provider may prescribe a medicine called a muscle relaxant. Despite its name, it does not work directly on muscles. Instead, it works through your brain and spinal cord.

This drug is often given along with over-the-counter pain relievers to relieve the symptoms of back pain or muscle spasm.

Examples of muscle relaxants include:

  • Carisoprodol
  • Cyclobenzaprine
  • Diazepam
  • Methocarbamol

Side effects of muscle relaxants are common and include drowsiness, dizziness, confusion, nausea, and vomiting.

These medicines can be habit-forming. Talk to your provider before using these drugs. They may interact with other medicines or make certain medical conditions worse.

Do not drive or operate heavy machinery while taking muscle relaxants. Do not drink alcohol while taking these drugs.


Antidepressants are normally used to treat people with depression. But, low doses of these medicines can help with chronic low back pain, even if the person does not feel sad or depressed.

These drugs work by changing the levels of certain chemicals in your brain. This changes the way your brain notices pain. Antidepressants most commonly used for chronic low back pain also help you sleep.

Antidepressants most often used for back pain are:

  • Amitriptyline
  • Desipramine
  • Duloxetine
  • Imipramine
  • Nortriptyline

Common side effects include dry mouth, constipation, blurred vision, weight gain, sleepiness, problems urinating, and sexual problems. Less commonly, some of these drugs can also cause heart and lung problems.

Do not take these drugs unless you are under the care of a provider. Do not stop taking these drugs suddenly or change the dose without also talking with your provider.


Anticonvulsant medicines are used to treat people with seizures or epilepsy. They work by causing changes in the electric signals in the brain. They work best for pain that is caused by nerve damage.

These drugs may help some people whose long-term back pain has made it hard for them to work, or pain that interferes with their daily activities. They can also help relieve radiating pain that is common with back problems.

Anticonvulsants most often used to treat chronic pain are:

  • Carbamazepine
  • Gabapentin
  • Lamotrigine
  • Pregabalin
  • Valproic acid

Common side effects include weight gain or weight loss, upset stomach, loss of appetite, skin rashes, drowsiness or feeling confused, depression, and headaches.

Do not take these drugs unless you are under a provider’s care. Do not stop taking these drugs suddenly or change the dose without also talking with your provider.

How They Work, Common Types, Side-Effects, Abuse

If you have neck or back pain, or you’re dealing with some other condition that causes muscle spasms, your doctor might prescribe a muscle relaxer (or muscle relaxant) for you.

Having a muscle spasm means that one or more of your muscles is contracting and the twitching or cramping is out of your control. It can happen for a lot of different reasons, and can sometimes be very painful.

While there are many different treatments for pain, your doctor may decide that a muscle relaxer is the best solution for you.

When You Might Need a Muscle Relaxer

Your doctor might first suggest you try an over-the-counter medicine like acetaminophen (Tylenol) or ibuprofen (Advil) to treat your pain. But if those don’t work, or you can’t take them because you have another issue like liver problems or ulcers, you may need to try a muscle relaxant.

Muscle relaxants are ideally prescribed for acute rather than chronic pain. They may be an option if pain is preventing you from getting enough sleep. Because muscle relaxants cause drowsiness, they can help you get rest when you take them at night.

Side Effects

No matter what kind of muscle relaxer you take, it is common to have side effects. Some muscle relaxants, however, can have potentially serious side effects, like liver damage. Your doctor will work with you to find the medication that makes the most sense for your situation.

The most common side effects include:

You shouldn’t drink alcohol while taking muscle relaxants. These medications make it hard to think and function normally, even if you take a low dose, so combining them with alcohol can increase your risk of an accident.

You also shouldn’t drive or operate heavy machinery while taking muscle relaxants. Some muscle relaxers start working within 30 minutes of taking them, and the effects can last anywhere from 4 to 6 hours.

Addiction and Abuse

Muscle relaxants can be addictive for some people. Taking them without a prescription, or taking more than your doctor has recommended, can increase your chances of becoming addicted. So can using them over a long period of time.

Almost all cases of addiction and abuse are due to the drug carisoprodol (Soma), which is considered a schedule IV controlled substance. That’s because when the drug breaks down in your body, it produces a substance called meprobamate that acts like a tranquilizer. People who become addicted to carisoprodol sometimes abuse the drug because they are no longer using it for medical reasons, and they crave it.

Other kinds of muscle relaxants may be addictive too. Cyclobenzaprine (Flexeril) has also been linked to misuse and abuse.

With prolonged use you can become physically dependent on some muscle relaxants. This means that without the medication, you can have withdrawl symptoms. You may have insomnia, vomiting or anxiety when you stop taking it.

Baclofen vs. Flexeril: Comparing Different Muscle Relaxers

Baclofen, also known as Lioresal, Liofen, or Gablofen, is a gamma-aminobutyric acid (GABA) agonist and belongs to the class of drugs called skeletal muscle relaxants. There’s an oral version of it and one that can be injected directly into the spinal cord.

Flexeril, also known as Cyclobenzaprine, Amrix, and Fexmid, is also a drug belonging to the same class and is used orally.

Since the two drugs are similar, there’s often confusion on which one is better or stronger: Baclofen or Flexeril. So read along to have a comprehensive comparison of Baclofen vs. Cyclobenzaprine.

What are These Drugs Known to Treat?

The comparison between Baclofen vs. cyclobenzaprine starts at what conditions they’re known to treat. Lioresal is used for managing muscle spasticity in multiple sclerosis. This drug is an antispastic medication used primarily to treat muscle clonus, pain, rigidity, and spasm in muscles in case of multiple sclerosis. It is also indicated in spinal cord problems, treating alcoholism, and CNS lesions. There is decreased susceptibility to CNS depression with this antispastic agent.

Flexeril (Cyclobenzaprine) is indicated for treating pain and muscle spasms related to short-term skeletal problems and muscle pain. Cyclobenzaprine is a tricyclic antidepressant derivative. It acts on the brain stem region, relieving short-term musculoskeletal pain and improves mobility.

Gablofen is usually prescribed as a long-term treatment for people suffering from long-term diseases such as multiple sclerosis. The medications are not to be used interchangeably because they’re meant to be used for different types of treatments. Whether the patient goes for Baclofen or Flexeril depends on what they need it for.

Flexeril vs. Baclofen Side Effects

Since both of these drugs affect the skeletal muscles, they are not available over the counter; they shouldn’t be taken lightly. These drugs can help relieve muscular pain symptoms, but they come with their range of side effects. Therefore, there needs to be a closer look at Flexeril vs. Baclofen to weigh out the side effects of each.

Baclofen Adverse Effects that Are Similar to Flexeril Include:

  • Drowsiness
  • Headache
  • Dizziness
  • Confusion
  • Nausea
  • Constipation

Both of these drugs work similarly, which also means that most of the side effects of Flexeril vs. Baclofen are the same. However, that doesn’t mean all of them are the same. Some side effects are unique to the specific drug and how it reacts in the patient’s body.

The Table Below Provides the List of the Side Effects Which Are Different For Baclofen vs. Flexeril:

What are the side effects of Flexeril that are different from Baclofen? What are the side effects of Gablofen that are different from Flexeril?
Dry Mouth Vomiting
Blurred Vision Weakness
Abdominal discomfort or pain Seizures
Acid reflux Urinary retention or frequent urge to urinate
Nervousness Insomnia or difficulty in falling asleep
Unpleasant taste Hypotension
Fatigue Respiratory difficulties

Is Baclofen Stronger Than Flexeril?

Because of the similarities between the two drugs, there’s often a question of which one between Flexeril vs. Baclofen is stronger.

Is Baclofen stronger than Flexeril? Before we determine it, we have to compare the two. Cyclobenzaprine intake is expected only for short-term use, and patients cannot take it for longer than 2-3 weeks at a time. Lioresal, on the other hand, can be used long-term for individuals having multiple sclerosis. It helps to manage the signs and symptoms effectively.

Although the two are muscle relaxants, their indications are different. The strength of the two depends on the dosage and purpose for which each drug is used, so it isn’t easy to compare the strength of Baclofen vs. Flexeril.

In the case of multiple sclerosis, Lioresal is the drug of choice. However, for acute muscle pain and relief of spasms, Flexeril remains the primary medication.

On the other hand, while Flexeril is available as oral tablets only, Lioresal can be given intrathecally via Gablofen pump – a device placed surgically inside the body for continuous drug delivery.

Differences in the Mechanism of Action

Both drugs belong to skeletal muscle relaxants, and both of them aim to give relief from muscle spasms. Still, Gablofen acts primarily on the spinal cord, and Flexeril acts centrally, causing muscle relaxation. There are differences that set Baclofen vs. cyclobenzaprine apart.

Lioresal is capable of minimizing the severity and frequency of muscle spasms and co-occurring pain. The effect of Lioresal, when taken regularly, is seen quickly within a few days. But in most cases where it is prescribed, like when you use it for back pain, multiple sclerosis, spasticity, and others, it has to be taken for a long term.

The efficacy of the Flexeril 5 mg tablet, which is the standard dose given three times per day, is found to be connected to the sedative effect of the medication. All short-term muscle spasms and other related conditions can be treated with Flexeril.

Overdose Possibilities of Baclofen vs. Flexeril

Overdose on Gablofen occurs when the daily dose exceeds 200 mg and triggers neurological effects, delirium, seizures, and coma. The dose needs to be gradually increased and tapered to avoid withdrawal symptoms.

A Flexeril overdose occurs when taken in more significant amounts than its prescribed level of 30 mg per day. Overdose can also happen when they both are mixed with alcohol or other drugs. Flexeril is a relatively safe drug, and usually overdoses are not very serious.

Pregnancy Warnings

According to the FDA, Lioresal belongs to the C pregnancy category. That means the effects of doses of Lioresal medication on pregnant women have not been studied yet. Lioresal is known to cause fetal harm due to animal data. The drug is found in breast milk in traces of lactating mothers taking it orally. There isn’t any information available about Gablofen pregnancy effects when the drug is taken intrathecally. Whether the mother is taking Baclofen or Flexeril, she must do so after discussing it with the doctor in charge of treatment.

Abuse Potential

Since both of these drugs, cyclobenzaprine vs. Baclofen, can affect how the patient’s muscles work, it is assumed that they’re strong enough to cause addictions on their own. Flexeril doesn’t have a lot of potential for misuse when taken on its own since it doesn’t provide the user with any psychoactive effects. So there’s less of a chance that someone will misuse it. However, there are some indications that show that it can be intentionally misused.

As for Baclofen, it is also uncommon for this drug to be misused. However, the misuse isn’t unheard of. In the past ten years, there have been a few cases of Gablofen abuse. Notably, a case from 2016, where a 24-year-old male who was addicted to smoking was prescribed the drug as part of his addiction treatment and given a low dose prescription of Baclofen. He ended up abusing the drug, taking around 600 mg every single day. He was then put on treatment and slowly tapered off the drug.

Drug Interactions of Baclofen vs. Flexeril

Both Gablofen and Flexeril are potent drugs on their own, which is why it’s important that the patient sticks to their medical dosage and informs their physician or medical health professional if they’re taking anything else that could potentially interact with the drugs. Both Flexeril vs. Baclofen can have minor, moderate, or major interactions, leading to extreme side effects or even death.

Baclofen Interactions

When taken along with other drugs, it can cause increased suppression of brain function. Particularly taking tricyclic antidepressants with Lioresal may lead to muscle weakness. Monoamine Oxidase Inhibitors, if taken with Baclofen, cause lower blood pressure and marked brain function depression. Other drugs to avoid are opioids, Methadone and Buprenorphine. While taking Lioresal, alcoholic beverages should be avoided as Gablofen causes drowsiness and dizziness, which can worsen with alcohol intake.

Flexeril Interactions

Flexeril should not be taken with Monoamine Oxidase Inhibitors or even within two weeks of taking an MAOI. The adverse effects caused by the combination include convulsions, high fever, and even death. Flexeril interaction with alcohol, narcotics, benzodiazepines such as diazepam and lorazepam, and barbiturates can slow down the brain’s functions.

Gablofen Compared to Other Muscle Relaxants

Lioresal is a popular and first-choice treatment for muscle spasticity caused by spinal cord injuries or multiple sclerosis. However, it is not recommended for other types of muscle spasms. Apart from the specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal is not the best medicine to take. There are many alternatives available to Baclofen, but they treat only a specific type of muscle pain.

Baclofen vs. Methocarbamol

An option that is easy on the pocket and comparatively less sedating too is Methocarbamol. Methocarbamol has been studied for back pain, and results show it can result in complete pain relief. It can be a reliable alternative. Gablofen is a better option for spasticity and spinal cord diseases, while Robaxin is used mainly for muscle spasm issues.

Both medications can be dangerous when used in combination with other drugs or substances such as narcotics.

Baclofen vs. Phenibut

Both Phenibut and Gablofen are derived from GABA, but Gablofen is often prescribed for muscle spasticity and phenibut for anxiety. Therefore, they are different in their indications

Baclofen vs. Soma

Also known as Carisoprodol, Soma, much like Xanax, has the potential for being abused and therefore should be stopped if there is a concern or a patient’s predisposition to substance abuse. Choosing Gablofen over Soma is normal as Soma offers greater side effects. Also, avoid using Soma in people over 65 and always go for better options if available. Even if prescribed, use only for two to three weeks as prolonged use has no evidence of showing effectiveness.

Baclofen vs. Zanaflex

Also known as Tizanidine, Zanaflex is used for spasticity in patients with multiple sclerosis or cerebral palsy. The Tizanidine vs. Baclofen 10 pill comparison shows us that the latter has fewer side effects than Lioresal but the same level of effectiveness. However, it is not a first-line choice for back muscle pain or acute neck pain.

Baclofen OTC Alternatives

Gablofen over-the-counter alternatives can also be used as therapy for muscle spasms caused by acute lower back pain, tension headaches, or other similar conditions in different patients. Over the counter means that this medicine can be bought without a prescription, unlike Baclofen, which should be tried before one looks towards prescription medications.

However, it does not mean that people should use OTC alternatives without visiting a doctor or medical health professional. It is highly recommended not to practice self-medication and always get correct medical supervision.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are an OTC choice that can be used to treat muscle spasms and pain. Examples include Ibuprofen and Naproxen. Acetaminophen is another Gablofen OTC alternative that works well to help relieve muscle pain.

Here Is a List of Some Popular Gablofen OTC Alternatives:

  • Tylenol
  • Ibuprofen
  • Naproxen
  • Aleve
  • Robaxin
  • Skelaxin

Which Drug Will Be The Best Choice?

Gablofen vs. Flexeril comparison reveals in detail the similarities and differences between the two popularly prescribed muscle relaxants. While Gablofen and Flexeril are muscle relaxants, the former is the best choice for long-term use, while Flexeril is better for short-term use. Lioresal also will be the better option for the cases of multiple sclerosis, treating alcoholism and spinal cord issues. It is essential that before the patient takes the drug, they weigh out the pros and cons, take a look at the side effects and the potential interactions to make sure they don’t experience any significant adverse effects of using either drug. Then, go through the comparison between Baclofen vs. Flexeril. Lastly, they should also remember to stick to the prescription and if they notice any chance of an addiction, report it to their physician or medical health professional immediately.

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Page Sources

  1. Witenko, C., Moorman-Li, R., Motycka, C., Duane, K., Hincapie-Castillo, J., Leonard, P., & Valaer, C. (2014). Considerations for the appropriate use of skeletal muscle relaxants for the management of acute low back pain. P & T : a peer-reviewed journal for formulary management, 39(6), 427–435. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103716/
  2. Ghanavatian, S., & Derian, A. (2020). Baclofen. StatPearls [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK526037/
  3. Khan, I., & Kahwaji, C. I. (2020). Cyclobenzaprine. StatPearls [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK513362/
  4. Das, S., Palappalllil, D. S., Purushothaman, S. T., & Rajan, V. (2016). An Unusual Case of Baclofen Abuse. Indian journal of psychological medicine, 38(5), 475–476. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052965/
  5. Chou, R., Peterson, K., & Helfand, M. (2004). Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review. Journal of pain and symptom management, 28(2), 140-175. https://pubmed.ncbi.nlm.nih.gov/15276195/
  6. Cimolai, N. (2009). Cyclobenzaprine: a new look at an old pharmacological agent. Expert review of clinical pharmacology, 2(3), 255-263. https://pubmed.ncbi.nlm.nih.gov/24410704/
  7. FDA, LIORESAL ®INTRATHECAL (baclofen injection) https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020075s021lbl.pdf
  8. Drug Enforcement Administration Diversion Control Division Drug & Chemical Evaluation Section, CYCLOBENZAPRINE https://www.deadiversion.usdoj.gov/drug_chem_info/cyclobenzaprine.pdf
  9. Emrich, O. M., Milachowski, K. A., & Strohmeier, M. (2015). Methocarbamol in acute low back pain. A randomized double-blind controlled study. MMW Fortschritte der Medizin, 157, 9-16. https://pubmed.ncbi.nlm.nih.gov/26168743/

Published on: March 4th, 2019

Updated on: May 28th, 2021

After successful graduation from Boston University, MA, Sharon gained a Master’s degree in Public Health. Since then, Sharon devoted herself entirely to the medical niche. Sharon Levy is also a certified addiction recovery coach.

8 years of nursing experience in wide variety of behavioral and addition settings that include adult inpatient and outpatient mental health services with substance use disorders, and geriatric long-term care and hospice care.  He has a particular interest in psychopharmacology, nutritional psychiatry, and alternative treatment options involving particular vitamins, dietary supplements, and administering auricular acupuncture.

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90,000 Linking Dry Mouth to Prescription Drugs | Dry mouth

Prescription drugs and dry mouth

Over the past 20 years, most Americans believe that prescription drugs improve the quality of life of people (73 percent of those surveyed), as well as the quality of life of their loved ones (63 percent). More than half of the adult population currently takes prescription drugs, and one in five people takes four or more drugs a day.1.

Dry mouth or xerostomia is a condition that occurs when the human salivary glands do not function properly, which leads to insufficient secretion of saliva into the oral cavity. There are three pairs of large salivary glands in the mouth, and prescription drugs can affect each of them. If you are taking prescription drugs, please tell your doctor and dentist.

What medications cause dry mouth?
More than 500 different drugs cause dry mouth, and if the patient takes several different drugs, the likelihood of dry mouth increases.2, 3 The following classes of prescription drugs affect the salivary glands:

  • Antihistamines: Medicines in this category affect saliva production. They include: diphenhydramine, claritin, zyrtec, etc.
  • Antidepressants: People taking antidepressants will also experience dry mouth. These types of medications affect the amount of saliva produced. These include Zoloft, Flexeril, and Amitriptyline.
  • Antiemetic drugs: These are drugs that are prescribed to prevent nausea and vomiting during chemotherapy or radiation therapy, as well as motion sickness (for example: anzemet, domperidone).
  • Antihypertensives: Antihypertensive medications (eg aerosol salbutamol, Norvasc, and nivil) are taken to control blood pressure.
  • Antiparkinsonian drugs: Drugs in this category are prescribed to relieve symptoms of Parkinson’s disease and other forms of parkinsonism (eg, levodopa, cyclodol).
  • Antispasmodics: These drugs are used to treat and relieve colic and cramps in the stomach, small intestine, colon, and bladder (eg dicyclomine).
  • Antipsychotics: Drugs used for mental disorders, anxiety and depression (for example: Zoloft, Lexapro).
  • Sedatives: These are drugs that induce sedation by reducing agitation and irritability, relieving anxiety (eg amytal, valium, lunesta).

If you are taking any of these medications, talk with your doctor and dentist to find ways to cope with your dry mouth. There are prescription and over-the-counter medications available to relieve dry mouth. Just check with your healthcare professional or dentist.

1 USA Today / Kaiser Family Foundation / Harvard School of Public Health, The Public on Prescription Drugs and Pharmaceutical Companies, January 3-23,2008.
2 Porter SR, Scully C, Hegarty AM: An Update of the etiology and management of xerostomia, Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97: 28-46, 2004.
3 Sreebny LM, Schwartz SS: A reference guide to drugs and dry mouth, ed 2, Gerodontology 14: 33-47, 1997.

© Copyright 2011 Colgate-Palmolive

instructions for use, dosages, composition, analogs, side effects / Pillintrip


Frequency of the most common adverse reactions in 2
double-blind, placebo-controlled trials 5 mg (frequency> 3% per

N = 464
N = 249
N = 469
Drowsiness 29% 38% 10%
Dry mouth 21% 32% 7%
Fatigue 6% 6% 3%
Headache 5% 5% 8%

Adverse reactions that have been reported in 1% to 3%
patients were: abdominal pain, acid regurgitation, constipation, diarrhea
dizziness, nausea, irritability, decreased mental acuity, nervousness, top
respiratory infection and pharyngitis.

The following list of adverse reactions is based on
experience in 473 patients treated with FLEXERIL 10 mg in an additional control
clinical trials, 7607 patients in a post-marketing surveillance program, and
reports received since the sale of the drug. The overall incidence of adverse
responses among patients in the follow-up program were less than
frequency in controlled clinical trials.

Most Reported Adverse Reactions
FLEXIBILITY was drowsiness, dry mouth, and dizziness.The frequency of these
common adverse reactions were lower in the follow-up program than in
controlled clinical trials:

‡ Note: FLEXERIL 10 mg data is from one clinical
trial. FLEXERIL 5 mg and placebo data are from two studies.

Clinical studies with FLEXERIL 10 mg Observation program with FLEXERIL 10 mg
Drowsiness 39% 16%
Dry mouth 27% 7%
Dizziness 11% 3%

There were no less frequent adverse reactions
a noticeable difference in frequency in controlled clinical trials or in
observation program.Adverse reactions that have been reported in 1% to 3%
patients were: tiredness / tiredness, asthenia, nausea, constipation, dyspepsia, unpleasant
taste, blurred vision, headache, nervousness and confusion.

The following adverse reactions have been reported in
post-marketing experience or with a frequency of less than 1% of patients in
clinical trials with 10 mg tablet:

Body as a whole: Fainting; malaise.

Cardiovascular: Tachycardia; arrhythmia; vasodilation;
palpitations; hypotension.

Digestive: Vomiting; anorexia; diarrhea;
gastrointestinal pain; gastritis; thirst; flatulence; swelling of the tongue;
liver dysfunction and rare reports of hepatitis, jaundice and

Hypersensitivity: Anaphylaxis; angioedema;
itching; swelling of the face; hives; rash.

Musculoskeletal system: Local weakness.

Nervous system and psychiatrist: Convulsions, ataxia;
dizziness; dysarthria; tremor; hypertension; convulsions; muscle twitching;
disorientation; insomnia; depressed mood; abnormal sensations; anxiety;
excitation; psychosis, abnormal thinking and dreaming; hallucinations;
excitation; paresthesia; diplopia.

Skin: Sweating.

Special Senses: Ageusia; tinnitus.

Urogenital: Urinary frequency and / or retention.

Causal relationship unknown

Other reactions rarely reported for FLEXERIL below
circumstances in which a causal relationship cannot be established or communicated
for other tricyclic drugs are listed as warning information

Body as a whole: Chest pain; edema.

Cardiovascular: Hypertension; myocardium
heart attack; heart block; stroke.

Digestive: Paralytic ileum, discoloration of the tongue;
stomatitis; parotid tumor.

Endocrine: Inappropriate ADH syndrome.

Hematic and lymphatic: Purpura; Bone marrow
depression; leukopenia; eosinophilia; thrombocytopenia.

Metabolic, food and immune: Height and
lowering blood sugar levels; weight gain or loss.

Musculoskeletal system: Myalgia.

Nervous system and psychiatrist: Reduced or
increased libido; abnormal gait; rave; aggressive behavior; paranoia;
peripheral neuropathy; Bell’s palsy; change in EEG patterns; extrapyramidal

Respiratory: Shortness of breath.

Skin: Photosensitivity; alopecia.

Urogenital: Urinary disorders; dilatation
urinary tract; impotence; swelling of the testicles; gynecomastia; breast
extension; galactorrhea.

Drug abuse and dependence

Pharmacological similarities between tricyclic drugs
require that certain withdrawal symptoms be considered when using FLEXERIL
is introduced even if they have not been registered with this drug.
Abrupt discontinuation of treatment after prolonged administration can rarely lead to
nausea, headache and malaise. This is not indicative of addiction.


FLEXERIL may have life-threatening interactions with MAO
inhibitors.(See CONTRAINDICATIONS .)

FLEXERIL may enhance the effects of alcohol
barbiturates and other CNS depressants.

Tricyclic antidepressants can block antihypertensive
action of guanethidine and compounds of similar action.

Tricyclic antidepressants may increase the risk of seizures when
patients taking tramadol. †

† ULTRAM® (Tramadol HCl Tablets, Ortho-McNeil
ULTRACET® (Tamadol HCl and acetaminophen tablets,
Ortho-McNeill Pharmaceutical)

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Investigator’s final report on the death of Whitney Houston released. According to the findings of the investigation, the singer drowned due to “atherosclerotic heart disease and the effects of cocaine.” These were the preliminary results of the autopsy of the body of Houston, announced at the end of March. “We found that cocaine, along with heart failure, worsened Houston’s condition,” Los Angeles District Investigator Craig Harvey said at the time.”If her heart was okay and she didn’t use cocaine, she probably wouldn’t drown.”

Examination revealed 0.58 micrograms of cocaine per milliliter of the singer’s blood.

Blood samples were taken from a vein in the singer’s leg during an autopsy. Dr. Drew Pinski, who hosts his own talk show on American television, commented to CNN that the level of cocaine in the blood is considered moderate.

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“Remains of a white powdery substance were found on the bathtub,” McCracken wrote. “I also collected the remains of the white powdery substance in a drawer in the bathroom and from the bottom of the mirror that was in that drawer.” Investigators also found “many bottles of medicine” in the hotel room, but experts concluded that prescription drugs “did not contribute to death.”

Along with cocaine, forensic experts found traces of marijuana in Houston’s body, the calming Xanax, the muscle relaxant Flexeril, and the anti-allergenic drug Bendril.Blood levels of drugs were low.

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Whitney Houston, 48, was found dead in the bathtub of the Beverly Hilton Hotel on February 11 in Los Angeles. The singer’s assistant last saw her alive the day before at about 15.00. Houston was getting ready to take a bath before the preliminary Grammy Awards program, which was held at the hotel that night. When the assistant returned, the bathroom was locked. At about 3.35, he went inside and saw Houston “lying face down in a bathtub filled with water.” “The assistant called her bodyguard, and together they pulled the deceased out of the bath,” the report says. At 3.55, when the doctors arrived, the singer’s body was already lying on the floor in the living room.

Houston has received six Grammys and has sold 170 million albums, singles and videos in her career.In recent years, the singer has struggled with drug addiction.

💊 Cyclobenzaprine | Side effects, dosage, uses and more

Cyclozaprine Basics

  1. Cyclobenzaprine Oral Tablets are available in both generic and brand name formulations. Brand: Fexmid.
  2. It also comes in an extended-release capsule that you take by mouth.
  3. Cyclobenzaprine is used to relieve muscle cramps.It is used in conjunction with relaxation and physical therapy. It should only be used 2-3 weeks at a time.

Important warnings Severity warnings

  • Serotonin Syndrome Prevention: This drug can cause a life-threatening condition called serotonin syndrome. It happens when medications cause too much serotonin to build up in your body. Call your doctor right away if you have any symptoms of this condition.These include agitation (feeling aggravated or anxious), hallucinations (seeing or hearing something that isn’t there), seizures, or nausea. Your risk may be higher if you are taking cyclobenzaprine with other drugs that increase your risk of serotonin syndrome, such as antidepressants.
  • Effects on cardiac warning: This drug may cause cardiac arrhythmias (heart rhythm or rhythm problems). Your risk may be higher if you are taking a medication to treat depression or if you already have heart problems.If left untreated, these problems can lead to heart attack or stroke.
  • Central Nervous System Warning: This drug may cause drowsiness, dizziness, hallucinations (seeing or hearing that does not exist), and delusions (believing things that are not true). You should not drive or use a car while on this drug until you know how it affects you. Your risk may be higher if you are 65 or older.

What is cyclobenzaprine?

Cyclobenzaprine Urine Tablet is a prescription drug available as the brand name Fexmid .It is also available as a generic drug. The drugs usually cost less. In some cases, they may not be available in every strength or form as a branded version.

Cyclobenzaprine is also available as an extended release oral capsule. Branded version of the capsule Amrix .

Why is it used

Cyclobenzaprine is used for muscle relief. It helps relieve pain, stiffness, or discomfort caused by strain or injury to your muscles.It is used in conjunction with relaxation and physical therapy. It should only be used 2-3 weeks at a time.

Cyclobenzaprine can be used as part of combination therapy. This means you may need to take it with other medicines.

How It Works

Cyclobenzaprine belongs to a class of drugs called muscle relaxants. A class of drugs is a group of drugs that work in a similar way. These drugs are often used to treat similar conditions.

It is not known how this drug works to relax muscles. This can reduce the signals from your brain that tell your muscles to spasm.

Side effects Side effects Cyclobenzaprine

Cyclobenzaprine Utic Tablet may cause drowsiness or dizziness. This will most likely happen a few hours after taking it. It can have other side effects as well.

More common side effects

More common cyclobenzaprine side effects may include:

  • dry mouth
  • dizziness
  • fatigue
  • constipation
  • sleepiness
  • nausea
  • heartburn

Serious side effects

Call your doctor at once if you have a serious side effect.Call 911 if your symptoms feel life threatening or if you think you have a medical emergency. Serious side effects and their symptoms may include the following:

Heart problems. Symptoms may include:

  • fainting
    • heartbeat (fast or irregular heartbeat)
    • Confusion
    • speech or comprehension problem
    • loss of control or numbness in your face, arms, or legs
    • seeing problem in one or both eyes
    • Serotonin Syndrome.Symptoms may include:
  • Agitation (feeling worsened or anxious)
    • Hallucinations (hearing or seeing something that is not there)
    • 90,016 withdrawals 90,017

    • nausea
    • Disclaimer:

Our goal is to provide you with the most current and relevant information. However, since drugs affect each person differently, we cannot guarantee that this information includes all possible side effects.This information does not replace medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Interactions. Cyclobenzaprine can interact with other medications.

Cyclobenzaprine Oral Tablets may interact with other medicines, vitamins, or herbs you may be taking. Interaction is when a substance changes the way we work with drugs. This can be harmful or interfere with the work of the drug.

To avoid interactions, your doctor must carefully manage all of your medications. Be sure to tell your doctor about any medications, vitamins, or herbs you are taking. To find out how this drug might interact with something else you are taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with cyclobenzaprine are listed below.

Drugs you should not take with cyclobenzaprine

Do not take monoamine oxidase inhibitors (MAOIs) with cyclobenzaprine.This can lead to dangerous consequences in the body. Examples of these drugs include:


  • rasagiline
  • tranylcypromine
  • Taking this medication with an MAOI or within 14 days after stopping an MAOI may increase the risk of serious side effects. These include seizures.

Interactions that increase the risk of side effects

Taking cyclobenzaprine with certain medicines increases the risk of side effects from cyclobenzaprine.This is because the amount of cyclobenzaprine in your body is increasing. Examples of these drugs include:


  • , such as triazolam, alprazolam, and midazolam. You may be more calm and sleepy. Barbiturates
  • , such as phenobarbital. You may be more calm and sleepy. Certain medicines used to treat depression, such as
  • fluoxetine, venlafaxine, amitriptyline, or bupropion. You may have a higher risk of serotonin syndrome . Verapamil.
  • You may have a higher risk of Serotonin Syndrome. Anticholinergics
  • , such as tolerodine or oxybutynin. You may have an increased risk of certain side effects. These include dry mouth or inability to urinate. Interactions that could make your medicines less effective

When certain medicines are used with cyclobenzaprine, they may not work.An example of these drugs includes

guanethidine. Cyclobenzaprine may block the blood pressure lowering effect of guanethidine. This means that your blood pressure may rise. Disclaimer:

Our goal is to provide you with the most up-to-date and up-to-date information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information does not replace medical advice.Always talk with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and dietary supplements, and over-the-counter medications you are taking. Other warnings Cyclobenzaprine warnings

Cyclobenzaprine Oral Tablets contain multiple warnings

Allergy Warning

Cyclobenzaprine may cause a severe allergic reaction. Symptoms may include:

bad breath

  • swelling of throat or tongue
  • If you have an allergic reaction, call your doctor or local poison control center right away.If your symptoms are severe, call 911 or go to the nearest emergency room.

Do not take this drug again if you have ever had an allergic reaction to it. Recurrence can be fatal (cause of death). Interaction with alcohol

Use of beverages containing alcohol may increase the risk of dizziness, drowsiness, and decreased cyclobenzaprine activity. If you drink alcohol, talk to your doctor.

Warnings for people with certain health conditions

For people with urinary problems:

This drug may make your symptoms worse. For people with glaucoma:

This drug may make your symptoms worse. For people with liver problems:

If you have liver problems or a history of liver disease, you will not be able to clear this drug from your body. This can cause it to build up in your body.This increases the risk of side effects. You should not use the extended form of this drug if you have liver problems. Warnings for other groups

For pregnant women:

Cyclobenzaprine is a pregnancy category B. This means two things: Animal studies have shown no risk to the fetus when the mother takes the drug.

  1. There are insufficient human studies to show whether a drug is a risk to the fetus.
  2. Talk to your doctor if you are pregnant or planning to become pregnant. Animal studies don’t always predict how humans will react. Therefore, this medication should only be used during pregnancy if clearly needed.

Women who are breastfeeding:

Cyclobenzaprine can pass into breast milk and may cause side effects in a breastfeeding baby. Talk to your doctor if you are breastfeeding.You may need to decide whether to stop breastfeeding or stop taking this drug. For the elderly:

The kidneys and liver of older people may not function as well as they used to. This can cause your body to process medications more slowly. As a result, more drugs remain in your body for a longer time. This increases the risk of side effects. If you are over 65, you should not use the extended-release form of this drug. For children:

Oral tablets should not be used in people younger than 15 years old. The extended dispensing form of this drug should not be used by people under the age of 18. Dosage How to take cyclobenzaprine

This dosage information is for cyclobenzaprine oral tablet and extended-release capsule. All possible doses and dosage forms cannot be included here. Your dose, dosage form, and how often you take the drug will depend on:

your age

  • Condition that is being treated
  • how bad is your condition
  • other medical conditions you have
  • How do you react to the first dose
  • Forms and strengths


Cyclobenzaprine Form:

  • Oral Tablets Strengths:
  • 5 mg, 10 mg Brand:> Fexmid

Form: Oral tablets

  • Strengths: 7.5 mg
  • Brand: Amrix

Form: Extended-release oral capsule

  • Strengths: 15 mg, 30 mg
  • Muscle Spasm Relief Dosage Adult (Ages 18-64)

Oral tablet: 5-10 mg taken 3 times a day

Extended-release oral capsule: 15 mg taken once daily.If your muscle cramps do not improve, your doctor may increase your dose to 30 mg per day.

  • Child dosage (ages 15-17)
  • Oral tablet: 5-10 mg taken 3 times a day

Extended-release oral capsule: This form should not be used by people under the age of 18.

  • Child dosage (ages 0-14)
  • Cyclobenzaprine should not be used in people younger than 15 years old.

Senior dose (age 65 and over)

The kidneys of older people may not work as well as they used to. This can cause your body to process medications more slowly. As a result, more drugs remain in your body for a longer time. This increases the risk of side effects.

Oral Tablet: Your doctor may start you on a lower dose or on a different dosing schedule. This can help keep the levels of this drug too high in your body.

Extended-release oral capsule: People aged 64 and over should not use this form.

  • Special Considerations:
  • People with liver problems:

Oral tablet: If your liver problems are mild, your doctor may start you on a lower dose or on a different dosing schedule. This can help keep the levels of this drug too high in your body. If your liver problems are moderate or severe, you should not use this medication.

Extended-release oral capsule: If you have liver problems, you should not use this form of the drug.

  • Disclaimer:
  • Our goal is to provide you with the most up-to-date and up-to-date information. However, since medications affect each person differently, we cannot guarantee that this list includes all possible doses. This information does not replace medical advice. Always talk to your doctor or pharmacist about the dosages that are right for you.

Take this as directed. Take it as directed. Cyclofenzaprine tablet tablet is used for short-term treatment. You should not use this medication for more than 3 weeks. Cyclobenzaprine is risky if you do not take it as prescribed.

If you stop taking the drug suddenly or do not take it at all:

Your symptoms may get worse. You may have more muscle cramps or pain.

If you miss doses or do not take a drug on schedule: Your drug may not work or it may stop working completely. For this drug to work well, a certain amount must be in your body at all times.

If you take too much: You may have dangerous levels of the drug in your body. Overdose symptoms of this drug may include:

fainting heartbeat (fast or irregular heartbeat)

  • Confusion
  • speech or comprehension problem
  • loss of control or numbness in your face, arms, or legs
  • trouble in one or both eyes
  • Agitation (feeling aggravated or anxious)
  • hallucinations (hearing or seeing something that is not there)
  • 90,016 withdrawals 90,017

  • nausea
  • If you think you have taken too much of this drug, call your doctor or local poison control center.If your symptoms are severe, call 911 or go to the nearest emergency room right away.
  • What if you miss a dose:

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This can lead to dangerous side effects.

How to tell if a drug is working: You should have less muscle pain and stiffness.

Important considerations. Important considerations. Important considerations for taking cyclobenzaprine. Keep these considerations in mind if your doctor prescribes a cyclobenzaprine tablet for you.


You can take cyclobenzaprine with or without food.

Take this drug at about the same time every day.

  • You can cut or crush your tablet. Do not cut, crush, chew, or open capsules.
  • Not every pharmacy stocks this drug. When filling out a prescription, be sure to call ahead.
  • Storage
  • Store cyclobenzaprine at 77 ° F (25 ° C).

Keep it away from light.

  • Do not store in damp or humid areas such as bathrooms.
  • Inserts
  • Prescription for this reusable drug. You will not need to enter a new prescription for this medication.Your doctor will write down the number of refills authorized for your prescription.


When traveling with your medicine:

Always carry your medicine with you. When flying, never put it in a checked bag. Keep it in your carry bag.

Don’t worry about X-ray machines at the airport. They cannot damage your medications.

  • You may need to show airport staff the pharmacy label for your medications.Always carry the original prescription-labeled box with you.
  • Do not put this medication in your car’s glove box or leave it in your car. Be sure to avoid this when the weather is very high or very cold.
  • Clinical monitoring
  • If you have liver problems, you may have a blood test to monitor how well your liver is working while you are taking this drug.


Many insurance companies require prior authorization for this drug.This means that your doctor must get permission from your insurance company before your insurance company pays for the prescription.

Alternatives Are there alternatives?

There are other medicines available to treat your condition. Some may be better for you than others. Talk with your doctor about other drug options that might work for you.


Healthline has made every effort to ensure that all information is factually correct, comprehensive and current.However, this article should not be used as a substitute for the knowledge and experience of a licensed healthcare professional. You should always check with your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all potential uses, directions, precautions, warnings, drug interactions, allergic reactions, or side effects.The absence of warnings or other information for a given drug does not mean that the drug or drug combination is safe, effective, or appropriate for all patients or for all specific purposes.

90,000 Dosages per cyclobenzaprine, species, concentration and safety information – Drug Information

Information for the medication Cyclobenzaprine can help you smear your muscles with spasms. Crawl the Nashata scheme for a dose of cyclobenzaprine, then pre-dose the dose.

Form and strength of the country | For growing up | For children | Dose Limitations for Cyclobenzaprine | Cyclobenzaprine for Pets | How to take cyclobenzaprine | Inquire honestly

Cyclobenzaprine hydrochloride is a generic skeletal muscle relaxant, used for soothing muscle spasms, often in combination with a non-prescription reliever cato aspirin, ibuprofen, or acetaminophen. We offer all and under the brand name Fexmid, cyclobenzaprinte tricyclic agent.Toy relax muscles with spasms and muscular pain, kato soothes the central nervous system (CNS), muscular hyperactivity. Cyclobenzaprine is a tablet, which can be taken up to three days a day for three weeks. We offer it in capsules with udlzheno release, koito izisquat itself a single daily dose.

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CONNECT: Teach you more for cyclobenzaprine | You will drop off the packaging for cyclobenzaprine

Forms and concentrations for cyclobenzaprine

Cyclobenzaprine tablets are available in three different dosages.

  • Tablet: 5 milligrams (mg), 7.5 mg and 10 mg tablets

Cyclobenzaprine Sesho offers 15 mg or 30 mg capsules with extended release kato rodovo or kato Torgovka brand Amrix.

Dosage for cyclobenzaprine per ages

Cyclobenzaprin is approved by the FDA for short term treatment for muscle spasms, but has been suggested to withdraw the label for treatment for fibromyalgia.

Diagram for dosage for cyclobenzaprine
Indication Initial dose Standard dosage Maximum dose
59053 mg daily for up to 3 weeks 5-10 mg, for up to 3 days for up to 3 weeks 10 mg, for up to 3 days for up to 3 weeks
Fibromyalgia 10 mg every evening before lagane 5-40 mg per day, divided between 1-3 doses 40 mg per day

Dosage for cyclobenzaprine for muscle spasms

As a rule, cyclobenzaprine is a frequent treatment regimen, which is commonly used, including kidney and physical therapy.

  • Ages and young men at 15 and over: 5-10 mg, intake up to three pips per day Spore need up to three weeks for muscle spasms
  • Maximum inhibitory dose for muscle spasms: Not more severe from taking three days a day for a period of at least three weeks

Dosage for cyclobenzaprine for fibromyalgia

Despite the fact that cyclobenzaprin is approved for treatment of muscle spasms, deliver to the health services there is no need to prescribe a prescription for please with fibromyalgia.Doziraneto obiknoveno se izvrshva predi lagane, for and se subpopogne taking off. Thy kato cyclobenzaprint all prescription for fibromyalgia withdrawal, dosage and duration of treatment is not standardized.

  • Age: 5-10 mg predilagane and can be increased if necessary to the maximum daily dose from 40 mg per day, which can be divided between one to three doses
  • Maximum dose for fibromyalgia : 40 mg per day

Cyclobenzaprine dosage per decade

Cyclobenzaprine is approved for use in young men aged 15 and over for muscle spasms.Young men get a dose and long-term treatment to grow up.

Dose limits for cyclobenzaprine

Dose for cyclobenzaprine may be as small as possible depending on whether or not by age or distance. T’y kato is a drug that prevents blackening of the shot, khorata with impaired black function can and will calm down, someone taking cyclobenzaprine, chipped off by other patients. As a result, on the basis of the delivery of services to health services, the dose will be recorded from the bottom, which will be the subject of attention.Format with udlzheno liberated on cyclobenzaprine se izyagva nay-dobre from the growing chorus and face with black problems.

While the page has a positive effect on sedation, cyclobenzaprine is not a precursor to drug abuse or dangers of effectiveness.

Cyclobenzaprine not only for the chorus with:

  • rhythm)
  • Congestion of cardiac insufficiency
  • Disorders of the block and other problems of consumption of cardiac conductivity (electric system on srceto)
  • Recovered from heart attack

Cyclobenzaprine has never been given for family medications, monotherapy with a prescription, koito lecuwat depression, bacterial infections, cancer or pain on Parkinson’s.In essence, cyclobenzaprine should not be taken in a box for 14 days after the MAOI.

For a choir with a bbrech or black-and-white problem and dose some mogat and all corigirate, like the following:

  • Innocuous patient care (abnormally ill) : Not defined :
    • Leko is blackly damaged: Format with extended release.Unfamiliarly released format can be zipped from 5 mg per den and the dosage is more than increased as required
    • Moderate to severely damaged: Not all preparations

Dosage for cyclobenzaprine for home favorite from the FDA for use with animals. The medicine can be toxic to stomach. A pet who has consumed cyclobenzaprine is suspected of showing adverse effects, honesty from sedation, depression, apathy and lack of coordination.Ako’s pet is accidentally consumed with cyclobenzaprine, it’s an unforgettable veterinary aid on the line.

How to take cyclobenzaprine

Cyclobenzaprine Used up to three days a day. Can be used with or without storage.

  • Vychiyat the medication As soon as the medication is taken out. Do not crawl away from this.
  • Sip a tablet with water from a bowl.
  • Vzmete tova medicine for one meal and for a while all day.
  • Store the product at a temperature (68 ° to 77 ° F) away from light, fuel and moisture.

Capsulite with udlzheno liberation, but not receive the wedge sutrins.

  • Sink the capsule with a small bowl of water. Do not wet or dab.
  • Ako you can’t eat the tyala capsule, you can open it and let me eat it in a single soup, a spoonful of apple puree. Absorb the displacement of the Vednaga, without yes. You will cry tired, for yes sigurni, why the medicine is not consumed.Do not spare the shift, for yes I will crawl in a clear way.

Honesty of asking for dosage for cyclobenzaprine

How long will you spend on cyclobenzaprine?

A single dose of cyclobenzaprine with an unforgettable release can take one hour, and after work and four hours, after reaching the peak concentration in krvta. T’y kato cyclobenzaprin is not all diluted with good water and it is difficult to absorb on the stomach tissue, maybe a single dose of cyclobenzaprine can be taken over four hours after reaching the peak concentration in the blood.Ima golyama exchange in tova khorat dobro khorat absorbs the substance of the condom, so that the peak concentration can be varied significantly from people to people.

How long will the cyclobenzaprint leave your system?

Cyclobenzaprint can take several days into the body. Hello, experts will measure the duration of the medication given through the half-stomach, the duration of the medication, it is necessary to take the medication slowly and eliminate, either through uncredited, or through excretion.Cyclobenzaprint ima having exchanged a lot of half-belly — up to 37 o’clock — the absorbent cathode is relatively good and premined before nyakolko fazi on eliminiran.

What’s the missed dose of cyclobenzaprine?

Cyclobenzaprine Reconsidered Please do not take a dose of spore. If you take cyclobenzaprine, you can take the missed dose and remember. But it’s almost time for the next dose, take it out until the next dose, and then you’ll take a bitch.Do not take any additional medication, but make up for the missed dose.

Acceptance for medicines three days a day can be difficult but not fully comprehended. You will disperse the forest and leave a dose and so on. For yes ste sigourne, if you take any dose at a time, check it out and follow:

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  • How to dose si k’m important for the daily slaughter, kato stavane sutrins, obyad or supper.
  • Crawl your smartphone, tablet or personal home assistant, and signal when you have a dose.
  • Write the si of the squirrel and the gi, leave the kato masata at the strategically located places for the meal or the entrance gate.
  • Drink a pharmacist for a dispenser for reminders for medications, monitoring for doses or caps for bottles for an alarm / chronometer, and for help with managing it on a daily dose.

What are the benefits of taking cyclobenzaprine?

Acceptance of spared instructions within a short period, cyclobenzaprinting can be safely terminated without problem. If taken over a long period or in excess, cyclobenzaprine can cause symptoms in otnemane.Despite the fact that the FDA has not approved the short-term treatment itself, long-term treatment with cyclobenzaprine may be prescribed for muscle pain, chest pain, or fibromyalgia.

Cyclobenzaprinting is intended even for about two weeks – three weeks – for muscle spasms. Continued use, dori at niski dosi, for cyclobenzaprine can be brought to otnemane for a tricyclic agent. Symptoms include stomach-borne distress, eating and drinking problems, and problems with movement, which usually lasted about two days.It’s unpleasant, but it’s not frightening or long-lasting.

What is the maximum dose for cyclobenzaprine?

Maximalnata preparative dose of cyclobenzaprine E 30 mg daily for muscle cramps and 40 mg daily for fibromyalgia, usually divided into three days tablet dose with a memorable release or a single daily dose capsule with extended release. Khorata at age or koito has black problems and may not be able to get the maximum dose and not rag but take the capsule with an extended dose.

What is the interaction with cyclobenzaprine?

Cyclobenzaprine can be taken with or without storage. Pieneto on alcohol e ni-dobre yes, if you take cyclobenzaprine, you can combine it with alcochol with cyclobenzaprine. You can sedate the drug pages. If you start eating it and take cyclobenzaprine in combination with opiate soothing, barbiturati, benzodiazepine, or other prescription or over-the-counter medications, koito will cause sedation.

Cyclobenzaprine cannot be taken with a drug called monoamine oxidase inhibitor. Combining cyclobenzaprine with MAO inhibitori significantly increases the risk of serotonin syndrome, and has the potential for abdominal distress.

Cyclobenzaprint is an influencing and chemical friend called acetylcholine. Medicines kato cyclobenzaprine, koito block acetylcholine, semen anticholinergics. Combine cyclobenzaprine with other anticholinergics, tricyclic antidepressants, or anxiety medications, which may increase the risk of anticholinergics.

And nakraya, khorata, who take tramadol, there is no risk from hirchove, who also take cyclobenzaprine.

As you can see, many drugs interact with cyclobenzaprine. Nay-do-it-you-your-yat is the supplier for the health of the grits and pregleda your list with the medicine, before you take cyclobenzaprine together with other medicines.

Svarzani resources for dosages for cyclobenzaprine:

  • Prescribed information on Amrix, National Library of Medicine at SASCH
  • Cyclobenzaprine, Epokrat
  • Cyclobenzaprine, StatPearls
  • National Information for
  • Cyclobenz Prescribed 16 Information for Medicine, Cyclobenzaprine HCl, National Library of Medicine at SASCH

  • Prescribed information at Fexmid, National Library of Medicine at SASCH
  • Long-term use of cyclobenzaprine for a bolka: pregled on clinical efficacy, Generalization on evidence of toxicity Veterinary relevance
  • on Merck
  • Evaluation of pharmacokinetics and bioequivalence on cyclobenzaprine tablet, BioMed Research International
  • Symptoms on otnemann from tricyclic antidepressant, B Canadian Medical Association Newsletter
  • Tricyclic Otneman Syndrome on Antidepressant, Analyze Pharmacology

How to Choose the Best OTC Muscle Relaxant?

Muscle relaxants, or skeletal muscle relaxants in particular, interact with the neuromuscular system to tone down and “relax” muscles.Usually indicated for muscle spasm or hyper-flexion, common muscle relaxants include cyclobenzaprine and methocarbamol, among other medications. Depending on where you live, muscle relaxants can only be achieved with a prescription. In the United States, a prescription is required for any muscle relaxant, although over-the-counter muscle relaxants are available in Canada and the United Kingdom.

Although OTC muscle relaxation products are available in the United States through online orders, ordering drugs online is discouraged because not only is it illegal to obtain prescription drugs without a prescription, but the quality and content of the drug is unknown.and is not regulated from many sources. If you live outside the United States, you can find over-the-counter muscle relaxation products at your pharmacy. They may also contain a pain reliever.

In the United States, muscle relaxants can be obtained with a prescription as directed by your doctor. An alternative to prescription muscle relaxants is to try natural foods that have muscle relaxant properties. These include rosemary, catnip, verbena, and cava root.These herbal products can usually be found in stores that specialize in vitamins and herbal supplements, but it is important to note that just because a product is “herbal” or “natural” does not mean there is no risk or drug interactions. You should consult your doctor, pharmacist, or herbal professional before taking any herbal supplements on your own.

Whether you are taking prescription or over-the-counter muscle relaxants, it is important to understand how they work and what they are used for.Some muscle relaxants, even herbal ones, are very effective and can affect people in different ways. Drowsiness, dizziness, and sedation are common side effects of muscle relaxants, and they can interfere with normal activities, especially driving or operating machinery. Although it is effective even in small doses, make sure you know how the drug is affecting you before trying to drive. It is also known that alcohol enhances the effect of muscle relaxants.