Flomax for Females: Effectiveness of Tamsulosin in Treating Women’s Voiding Difficulties
How effective is tamsulosin in treating women with voiding difficulty. What are the benefits of using Flomax for females with urinary issues. Can Flomax help women with bladder outlet obstruction or detrusor underactivity.
Understanding Tamsulosin and Its Use in Female Urinary Issues
Tamsulosin, commonly known by its brand name Flomax, is an alpha-blocker medication primarily prescribed to men with benign prostatic hyperplasia (BPH). However, recent studies have explored its potential benefits for women experiencing urinary difficulties. This article delves into the effectiveness of tamsulosin in treating women with voiding problems, providing insights into its mechanism of action and potential applications.
What is Tamsulosin and How Does It Work?
Tamsulosin is an alpha-1 adrenergic antagonist that relaxes smooth muscles in the bladder neck and prostate, facilitating urine flow. In women, it may help alleviate urinary symptoms by relaxing the muscles around the urethra and bladder sphincter. This action can potentially improve urine flow and reduce voiding difficulties in female patients.
Evaluating Tamsulosin’s Effectiveness in Women with Voiding Difficulty
A prospective study was conducted to assess the efficacy of tamsulosin in treating women with chronic, bothersome voiding symptoms. The research involved 97 female patients who met specific inclusion criteria, including subnormal uroflow and persistent voiding issues.
Study Methodology
- Patients were administered 0.2 mg of tamsulosin daily for six weeks
- Outcome measures included the International Prostate Symptom Score and uroflowmetry with post-void residual urine
- A good therapeutic response was defined as a 50% or greater reduction in voiding symptom score and a 30% or greater increase in maximal flow rate
- Subgroup analysis was performed on patients with bladder outlet obstruction or detrusor underactivity
Key Findings: Tamsulosin’s Impact on Female Voiding Symptoms
The study revealed significant improvements in various urinary parameters for women taking tamsulosin. These results provide valuable insights into the medication’s potential benefits for female patients with voiding difficulties.
Overall Improvements Observed
How did tamsulosin affect urinary symptoms in the study participants. The research showed notable improvements in:
- Voiding symptom score
- Storage symptom score
- Maximal flow rate
- Post-void residual urine
- Voiding efficiency
These improvements were observed across all patients in the study, suggesting a broad positive impact of tamsulosin on female urinary function.
Therapeutic Response Rate
What percentage of women experienced a good therapeutic response to tamsulosin. The study found that 35.1% of patients achieved the criteria for a good therapeutic response. This indicates that more than one-third of women with voiding difficulties may benefit significantly from tamsulosin treatment.
Subgroup Analysis: Bladder Outlet Obstruction vs. Detrusor Underactivity
The study further analyzed the effects of tamsulosin on two specific subgroups of patients: those with bladder outlet obstruction and those with detrusor underactivity. This analysis provides insights into the medication’s efficacy for different underlying causes of voiding difficulties in women.
Comparative Results
How did tamsulosin’s effectiveness differ between the two subgroups. The study revealed:
- Both groups experienced significant reductions in voiding symptom scores
- Patients with bladder outlet obstruction were more likely to achieve a reduction in their voiding symptom score
- Improvements in uroflow parameters were similar between the two groups
- The proportion of patients achieving a good therapeutic response was comparable (39.4% for bladder outlet obstruction vs. 32.7% for detrusor underactivity, P = 0.69)
These findings suggest that tamsulosin may be beneficial for women with voiding difficulties, regardless of whether the underlying cause is bladder outlet obstruction or detrusor underactivity.
Safety Profile and Tolerability of Tamsulosin in Women
An important aspect of any medication’s use is its safety profile and tolerability. The study provided insights into how well women tolerated tamsulosin treatment.
Adverse Events
Were there any significant side effects reported during the study. The research found that adverse events associated with tamsulosin use in women were generally mild and tolerable. This suggests that the medication may have a favorable safety profile for female patients, although further long-term studies may be needed to confirm these findings.
Comparing Tamsulosin Use in Men and Women
While tamsulosin is primarily prescribed for men with BPH, its potential use in women raises questions about similarities and differences in its application between genders.
Mechanism of Action
How does tamsulosin’s mechanism of action differ between men and women. In men, tamsulosin primarily targets the prostate and bladder neck muscles. In women, who lack a prostate, the medication’s effects are focused on the muscles around the urethra and bladder sphincter. Despite this anatomical difference, the overall impact on improving urinary flow appears to be similar.
Dosage Considerations
Is the dosage of tamsulosin the same for women as it is for men. The study used a daily dose of 0.2 mg for women, which is lower than the typical 0.4 mg dose prescribed for men with BPH. This lower dosage may help minimize potential side effects while still providing therapeutic benefits for female patients.
Potential Applications of Tamsulosin in Female Urological Conditions
The positive results of this study open up possibilities for broader applications of tamsulosin in treating female urological conditions.
Expanding Treatment Options
For which female urological conditions might tamsulosin be considered as a treatment option. Based on the study results, tamsulosin could potentially be considered for:
- Chronic voiding difficulties in women
- Bladder outlet obstruction
- Detrusor underactivity
- Other lower urinary tract symptoms in women
However, it’s important to note that further research and clinical trials may be necessary to fully establish tamsulosin’s efficacy and safety for these conditions in female patients.
Future Research Directions for Tamsulosin in Women’s Urological Health
While this study provides valuable insights into tamsulosin’s potential benefits for women with voiding difficulties, it also highlights areas where further research is needed.
Long-term Effects and Safety
What aspects of tamsulosin use in women require further investigation. Future studies could focus on:
- Long-term efficacy and safety of tamsulosin in women
- Optimal dosing strategies for female patients
- Potential interactions with other medications commonly prescribed to women
- Effects on quality of life and overall urological health in women
These research directions could help establish more comprehensive guidelines for the use of tamsulosin in treating female urological conditions.
Comparison with Other Treatment Options
How does tamsulosin compare to other treatments for female voiding difficulties. Future studies could explore:
- Head-to-head comparisons with other medications used for female urinary symptoms
- Combination therapies involving tamsulosin and other urological treatments
- Cost-effectiveness analyses of tamsulosin compared to alternative treatments
Such research could help healthcare providers make more informed decisions when choosing treatment options for women with voiding difficulties.
Practical Implications for Healthcare Providers and Patients
The findings of this study have several practical implications for both healthcare providers and female patients experiencing voiding difficulties.
Considerations for Healthcare Providers
What should healthcare providers consider when contemplating tamsulosin for female patients. Key considerations include:
- Careful evaluation of the underlying cause of voiding difficulties
- Assessment of potential benefits versus risks for each individual patient
- Monitoring of treatment response and potential side effects
- Patient education about the off-label use of tamsulosin for female urinary issues
Healthcare providers should also stay informed about ongoing research and emerging guidelines for the use of tamsulosin in women.
Patient Education and Empowerment
How can female patients benefit from this information about tamsulosin. Patients should be encouraged to:
- Discuss their urinary symptoms openly with their healthcare providers
- Ask about potential treatment options, including tamsulosin
- Understand the potential benefits and risks of tamsulosin treatment
- Report any side effects or changes in symptoms during treatment
Empowering patients with knowledge about their treatment options can lead to more informed decision-making and potentially better outcomes.
Conclusion: Tamsulosin’s Promise in Women’s Urological Health
The study on tamsulosin’s effectiveness in treating women with voiding difficulties provides encouraging results. With a significant proportion of women experiencing improvements in their urinary symptoms, tamsulosin shows promise as a potential treatment option for female patients struggling with chronic voiding issues.
While further research is needed to fully establish its long-term efficacy and safety profile in women, the current findings suggest that tamsulosin could play a valuable role in expanding treatment options for female urological conditions. As research in this area continues to evolve, healthcare providers and patients alike should stay informed about the potential benefits and considerations of using tamsulosin for women’s urinary health.
Ultimately, the goal is to improve the quality of life for women experiencing voiding difficulties, and tamsulosin may offer a new avenue for achieving this objective. As with any medical treatment, decisions about using tamsulosin should be made on an individual basis, taking into account each patient’s unique circumstances and needs.
The effectiveness of tamsulosin in treating women with voiding difficulty
Objectives:
To prospectively evaluate the effectiveness of tamsulosin in treating women with voiding difficulty.
Methods:
Female patients presenting chronic, bothersome voiding symptoms, combined with subnormal uroflow were treated with 0.2 mg tamsulosin daily for six weeks. Outcome analyses included the International Prostate Symptom Score and uroflowmetry with post-void residual urine. Patients achieving a 50% or greater reduction in their voiding symptom score, combined with a 30% or greater increment in their maximal flow rate were regarded as having a good therapeutic response. Subgroup analysis was performed in patients classified as having bladder outlet obstruction, or detrusor underactivity based on pressure-flow study, excluding those with indwelling catheterization or intermittent self-catheterization as well as those with anatomic obstruction.
Results:
Ninety-seven patients met the study inclusion criteria and were enrolled. Significant improvements in voiding symptom score, storage symptom score, maximal flow rate, post-void residual urine and voiding efficiency were observed in all patients while on tamsulosin. A good therapeutic response was observed in 35.1% of patients. Of these, 33 were classified as having bladder outlet obstruction and 52 had detrusor underactivity. Although both groups experienced significant reduction in their voiding symptom scores, patients with bladder outlet obstruction were more likely to achieve a reduction of their voiding symptom score. The magnitude of improvement in uroflow parameters as well as the proportion of patients achieving a good therapeutic response (39.4% for bladder outlet obstruction vs 32.7% for detrusor underactivity, P = 0.69) were similar between the two groups. Adverse events were mild and tolerable.
Conclusions:
Tamsulosin has beneficial effects in a significant proportion of women with voiding difficulty.
Flomax for Women | Flomax Side Effects
Although commonly considered an alpha-blocker medication prescribed to men battling benign prostatic hyperplasia (BPH), Flomax can also be prescribed for women experiencing bladder blockages or obstruction to help them urinate more easily.
BPH is a condition that affects about 50 percent of men between the ages of 51 and 60 and up to 90 percent of men older than 80.
It occurs when the prostate, expands to twice or even three times its regular size.
The growing prostate gland gradually presses against the urethra, restricting urinary flow and resulting in urinary problems.
While Flomax has long been the mainstay of treatment for men with BPH and lower urinary tract symptoms (LUTS), little research has investigated the use of alpha-blockers in women.
This article will discuss the effectiveness of using Flomax for women.
What Is Flomax Used For?
As discussed, Flomax is generally used to relieve urinary symptoms associated with BPH. Doctors may also prescribe tamsulosin to help the body clear or pass kidney stones.
Flomax works by paralyzing the muscles around your urethra and your bladder sphincter. The sphincter muscles enable you to hold in your urine until you can get to a toilet.
However, although it helps to ease urination, it does not affect your prostate health whatsoever.
You may experience short-term relief of urinary symptoms, but it does not address the underlying cause.
A 2003 Cochrane systematic review looked at the effects of Tamsulosin for BPH. The analysis involved 14 studies, ranging between 1 to 6 months long.
Although the participants reported improvements in symptoms, it was also found that men reported dizziness, rhinitis, and abnormal ejaculation compared to the placebo group.
The authors of this review suggested a need for more extended studies looking at the long term effects was required.
A further known side effect of Flomax is hypotension. A study in the BMJ (October 26, 2015) revealed that alpha-blockers, such as Flomax, can increase the risk of falls. The study found a 15-16% increased risk for fractures and head trauma during the first three months of taking such medications.
Flomax is also used as a treatment for kidney stones. Kidney stones form as a buildup of various compounds that become sedimented in the upper urinary tract.
They often go unnoticed as they do not grow big enough and can be eliminated without causing any significant symptoms.
Flomax is known to relax the smooth muscle in the urinary tract. It may also reduce the effect of entrapment that often leads to urinary obstruction in cases of kidney stones.
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Flomax Warnings
Does Flomax have side effects?
The problem with the prescription medication is that it has side effects and like other drugs do. Here is a list of some of the long list of adverse effects from Flomax:
Pregnancy and Flomax
The FDA does not approve the use of Flomax for women, but Tamsulosin is sometimes prescribed off-label to women for the treatment of an overactive bladder, voiding in patients with multiple sclerosis (MS) and urinary retention.
Similar to the way it works for BPH, Tamsulosin is effective by relaxing the smooth muscle in the urinary tract.
Flomax is listed as a category B medication for pregnancy. This means that the side effects during pregnancy are unknown.
Tamsulosin interactions with
- Acid-blocking drugs, such as cimetidine
- Antifungal drugs, such as ketoconazole
- Medication for erectile dysfunction
Is Flomax Effective?
A review evaluated Tamsulosin for the treatment of lower urinary tract symptoms in women.
All trials showed statistically significant improvement with Tamsulosin in female lower urinary tract symptoms (especially in women with predominant voiding dysfunction) as well as improvements in quality of life and sleep quality.
However, people reported several side effects, including, dizziness and asthenia, stress incontinence and urgency, fatigue, drowsiness, and hypotension.
Tamsulosin has been studied and found helpful for reducing excessive nighttime urination in women.
269 patients completed a voiding diary, a questionnaire on the Medical Outcomes Study (MOS) sleep scale and underwent follow-up evaluation after 4 weeks of treatment (Tamsulosin, 0.2 mg, once daily).
The effectiveness of the treatment was assessed by analysis of the IPSS, the bother score, the Qmax, and postvoid residual urine (PVR).
Nocturia significantly reduces after tamsulosin treatment. Thereby, sleep quality also improves.
Although some studies suggest that Flomax can improve urinary symptoms in women, the majority of evidence suggests that Tamsulosin is moderately effective at best.
We need further long-term studie to evaluate the effectiveness of Flomax for women and the side effects that it can cause.
Meanwhile, extensive studies have reviewed the use of Flomax for men, especially in regard to treating BPH.
A large number of these studies have reported dangerous side effects associated with Flomax including; erectile dysfunction, hypotension, long-term incontinence, and floppy iris syndrome.
Women taking Tamsulosin or considering taking Tamsulosin should be made aware that taking this medication means that symptoms are unlikely to go completely.
It is also essential to bear in mind that Flomax can have significant side effects that can impact the quality of life. There are several natural alpha blockers that work in a similar way to Flomax, such as saw palmetto. and rye flower pollen.
Conclusion
The research into the effectiveness of Flomax for women remains limited. However, people report a number of side, and the FDA has not approved the use of the drug for women. Before taking Tamsulosin, speak with your doctor about the possible side effects.
Next Up
Find out 5 Natural Alternatives To Flomax.
Summary
Article Name
Flomax for Women – Ben’s Natural Health
Description
Flomax has long been the mainstay of treatment for men with BPH. However, little research has investigated the use of Flomax for women.
Author
Dr Alberto Parra
Publisher Name
Ben’s Natural Health Team
Publisher Logo
Clinical Management of Urinary Incontinence in Women
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Tamsulosin Controlled-Release Tablet – Oral
Pronunciation: tam-SOO-loe-sin
Common Brand Name(s): Flomax CR
Important: How To Use This Information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Uses
Tamsulosin is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night).
Tamsulosin belongs to a class of drugs known as alpha blockers.
Do not use this medication to treat high blood pressure.
Other Uses
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be used to help your body “pass,” or get rid of, kidney stones through urination. It may also be used for bladder problems in women.
How To Use
Read the Patient Information Leaflet provided by your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once daily.
Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
Tamsulosin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting. This risk is higher when you first start taking this drug or if you restart treatment after you stop taking it. During these times, avoid situations where you may be injured if you faint.
To avoid injury from dizziness or fainting, your doctor may tell you to take your first dose of tamsulosin at bedtime so that your body can get used to its effects.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
It may take up to 4 weeks before your symptoms improve. Tell your doctor if your condition does not improve or if it worsens.
Side Effects
Dizziness, lightheadedness, or ejaculation problems may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including:
Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
- rash
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US –
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking tamsulosin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
- low blood pressure
- certain eye problems (cataracts, glaucoma)
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Before having surgery (including cataract/glaucoma eye surgery), tell your doctor or dentist if you are taking or have ever taken this medication, and about all the other products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the side effects of this drug, especially dizziness and low blood pressure when getting up from a sitting or lying position. These side effects can increase the risk of falling.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.
Drug Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Some products that may interact with this drug include:
- other alpha blocker drugs (such as prazosin, terazosin)
If you are also taking a drug to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may need to adjust your medications to minimize this risk.
Other medications can affect the removal of tamsulosin from your body, which may affect how tamsulosin works. Examples include azole antifungals (such as itraconazole, ketoconazole), boceprevir, clarithromycin, cobicistat, HIV protease inhibitors (such as lopinavir, ritonavir), ribociclib, among others.
Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.
Notes
Do not share this medication with others.
Laboratory and/or medical tests (such as prostate exams, blood pressure) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Flomax Use In Female
Post Your Comments?
Flomax® (tamsulosin) for Urinary Issues in Women
6 hours ago Tamsulosin is the most well tolerated, with the most prominent side effect noted being dizziness. In some cases, alpha-blockers lead to worsened stress incontinence, so they may want to be avoided in female patients with stress incontinence. Tamsulosin is also commonly being prescribed for short-term use in women with kidney stones.
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Female, For
Flomax for Females?
4 hours ago In recent years, the use of tamsulosin has expanded to off-label indications in both men and women. Here is an overview. Off-Label Uses. The most common off-label use of tamsulosin is to assist in the passage of kidney stones by increasing urinary fluid volume and pressure as well as relaxing smooth muscle in the ureters. 2 Studies have
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Fluid
Usage of Flomax® (tamsulosin) in Women ICP
7 hours ago Studies have been conducted to verify the effectiveness of tamsulosin in women with BOO symptoms and have found that tamsulosin is a suitable option for initial treatment. References: Pischedda A, Pirozzi Farina F, Madonia M, Cimino S, Morgia G. Use of alpha1-blockers in female functional bladder neck obstruction.
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Found, For, Farina, Female, Functional
Flomax for Women Flomax Side Effects Ben’s Natural Health
6 hours ago Pregnancy and Flomax. The FDA does not approve the use of Flomax for women, but Tamsulosin is sometimes prescribed off-label to women for the treatment of an overactive bladder, voiding in patients with multiple sclerosis (MS) and urinary retention.. Similar to the way it works for BPH, Tamsulosin is effective by relaxing the smooth muscle in the urinary tract.
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Flomax, Fda, For
The effectiveness of tamsulosin in treating women with
1 hours ago Objectives: To prospectively evaluate the effectiveness of tamsulosin in treating women with voiding difficulty. Methods: Female patients presenting chronic, bothersome voiding symptoms, combined with subnormal uroflow were treated with 0.2 mg tamsulosin daily for six weeks. Outcome analyses included the International Prostate Symptom Score and uroflowmetry with post-void residual urine.
Publish Year: 2008
Author: Shang-Jen Chang, I-Ni Chiang, Hong-Jeng Yu
Website: Pubmed.ncbi.nlm.nih.gov
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Female, For
Tamsulosin for voiding dysfunction in women Database of
5 hours ago Research: The authors stated a need for a large randomised placebo-controlled trial to compare tamsulosin to placebo in female patients with voiding dysfunction. Future trials should also utilize 0.4 mg daily to minimise risk of under-dosing and to be comparable with studies that used tamsulosin for benign prostatic hyperplasia.
Publish Year: 2012
Author: Laura E. Meyer, Jamie N. Brown
Website: Ncbi.nlm.nih.gov
Category: Use for in a sentence
For, Female, Future
Flomax Uses, Dosage, Side Effects & Warnings Drugs.com
3 hours ago Flomax (tamsulosin) is an alpha-blocker that relaxes the muscles in the prostate and bladder neck, making it easier to urinate. Flomax is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate). Flomax is not approved for use in women or children. Warnings. You should not use Flomax if you are allergic to tamsulosin.
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Flomax, For
Tamsulosin for treatment of lower urinary tract symptoms
1 hours ago Tamsulosin has been used for the off-label treatment of lower urinary tract symptoms (LUTS) in women. Over the past few years, several randomized controlled trials (RCTs) have reported the clinical effectiveness and safety of tamsulosin for LUTS in women. Therefore, the aim of the present study was …
Publish Year: 2017
Author: H L Zhang, Z G Huang, Y Qiu, X Cheng, X Q Zou, T T Liu
Website: Pubmed.ncbi.nlm.nih.gov
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For, Few
9 Negative Side Effect Of Flomax Every Woman Women.com
9 hours ago Flomax, whose generic name is Tamsulosin, is an alpha blocker that works to treat symptoms of an enlarged prostate in males. While Flomax is only FDA approved for use in men, the medication is often prescribed to women with an overactive bladder or other urinary problems as well.
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Flomax, Fda, For
I am female why have I been given tamsulosin to take for
6 hours ago Yes, it is perfectly fine to take this medication as a women. It relaxes your Urinary Tract muscles and makes it easier to Urinate & pass a Kidney stone too. A lot of women actually take this medication for bladder issues. I personally take this medication myself for my bladder issues, I find it works well. I am a 21 year old female.
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Fine, For, Find, Female
Side Effects for Women Who Take Flomax Medicine Healthfully
4 hours ago Flomax is a medication approved by the Food and Drug Administration (FDA) for the treatment of male urinary symptoms caused by benign prostatic hypertention (BPH), which is an enlarged prostate 3. The FDA does not approve the use of Flomax for women. Some health care providers may recommend Flomax for “off-label” use.
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Flomax, Food, Fda, For
Can tamsulosin be used for women Answers from Doctors
1 hours ago can tamsulosin be used for women. A 53-year-old female asked: can women take flomax (tamsulosin)? Dr. Dan Fisher answered. 27 years experience Internal Medicine. Yes.: It may be indicated to help some kidney stones to pass. 2 doctors agree. 0. 0 …
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For, Female, Flomax, Fisher
How Does Flomax Work for Kidney Stones? Healthfully
5 hours ago How to Strain Urine for Kidney Stones. Learn More. Flomax is intended to ease the flow of urine associated with BPH. It is now being used, although still infrequently, to ease the passage of kidney stones through the urinary tract. Alpha-blockers, like Flomax, help dilate the urinary system to help pass a kidney stone at a quicker pace
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For, Flomax, Flow
Flomax use in women MedHelp
5 hours ago Flomax use in women. Common Questions and Answers about Flomax use in women. flomax. My urogynecologist had me try flomax, but unfortunately after a month it was apparent it was only making my urgency worse. I am troubled by retention and urgency.
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Flomax
Is Prostate Drug – Tamsulosin – Safe for Women? The
3 hours ago Our first reaction was that tamsulosin (Flomax) is approved only for men with enlarged prostate glands and not for women. Upon searching, however, we found that tamsulosin has been studied and found helpful for reducing excessive nighttime urination in women ( …
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Flomax use for women MedHelp
6 hours ago Hello, Flomax is used for the treatment of BPH and if you are having side effects to this drug then you can use other alpha blockers like doxazosin, terazosin, alfuzosin or 5 alpha reductase inhibitors like finasteride and dutasteride. Effects may take longer to appear than alpha blockers, but they persist for many years. But they are available under prescription and should always be taken
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Flomax, For, Finasteride
Flomax (Tamsulosin Hydrochloride): Uses, Dosage, Side
8 hours ago FLOMAX capsules are not indicated for use in women. Pediatric Use. FLOMAX capsules are not indicated for use in pediatric populations. Efficacy and positive benefit/risk of tamsulosin hydrochloride was not demonstrated in two studies conducted in patients 2 years to 16 years of age with elevated detrusor leak point pressure (>40 cm h3O
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Flomax, For
Flomax for women: let’s discover the details ehealthyzone
8 hours ago Flomax, AKA tamsulosin, is considered to be a drug only for men with benign prostatic hyperplasia. It helps such men in improving the urine flow when their prostate becomes too large to obstruct the urine flow. Flomax is used for men, but, some studies have proved that women can also use Flomax if they have any issues in the urine flow.
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Flomax, For, Flow
Flomax use in females LambertMaupin’s blog
3 hours ago Flomax Side Effects In Females. Flomax, the brand name for the drug tamsulosin, is an alpha-adrenergic blocker typically used to relax the muscles in the prostate and. Can the Flomax be prescrived to a female to help pass kidney. Flomax for bladder infection, flomax dosing, flomax bloating, tamsulosin 400mg side effects and diovan with flomax.
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Flomax, Females, For, Female
Tamsulosin Women’s Health Associates for Women’s
1 hours ago Tamsulosin is an alpha-blocker that is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate). Tamsulosin is not approved for use in women or children. Tamsulosin may also be used for purposes not listed in this medication guide.
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For
Flomax: Uses, Taking, Side Effects, Warnings Medicine.com
6 hours ago What is Flomax? Flomax is a prescription alpha-blocker medicine used to treat the signs and symptoms of benign prostatic hyperplasia (BPH), a condition your doctor may refer to as an enlarged prostate.. Flomax is not for women. Flomax is not for children.
Occupation: Senior Editorial Pharmacist
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Flomax Oral: Uses, Side Effects, Interactions, Pictures
9 hours ago Tamsulosin is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH).It does not shrink the prostate, but it works by relaxing the muscles in the prostate and
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Flomax For Women? General Nursing allnurses
7 hours ago Flomax has only been FDA approved for male patients and has no information with the use in women because no studies have been done. But, as we are all aware of there are alpha 1 receptors in male and female bladder necks of the urethra, which can help relax the muscles for urine to flow better without or with reduced spasms and hesitation.
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Flomax, Fda, For, Female, Flow
Flomax use in women Student Doctor Network Communities
8 hours ago Flomax causes relaxation of the trigone muscle in the neck of the bladder (via the alpha-1-a receptors). Relaxation of the muscle facilitates the release of urine. This female patient must be having difficulty urinating. LexiComp said: Tamsulosin is …
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Flomax, Facilitates, Female
Tamsulosin (Flomax): Basics, Side Effects & Reviews
1 hours ago No, tamsulosin (Flomax) doesn’t help with hair growth. There are other medications used for BPH that can be used for hair growth, such as dutasteride (Avodart) and finasteride (Proscar) which work differently than tamsulosin (Flomax). Dutasteride (Avodart) and finasteride (Proscar) are 5-alpha reductase blockers (which help bring down prostate size), while tamsulosin (Flomax) is an alpha-1
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Flomax, For, Finasteride
PIC QUESTION OF THE WEEK 8/28/06 Duquesne University
4 hours ago A: Tamsulosin (Flomax®) is a selective alpha-1a/1d adrenergic antagonist indicated for the treatment of benign prostatic hyperplasia (BPH). It has also been used off-label to increase the passage of ureteral stones (men and women), improve bladder storage in patients with spinal cord injury, and reduce symptoms in males with
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Flomax, For
Flomax Side Effects: What You Need to Know
1 hours ago Flomax is only approved by the FDA for use in men to treat BPH. However, research has indicated that Flomax is also an effective treatment for women who have trouble emptying their bladders.
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Flomax, Fda, For
How effective is Flomax for Urinary retention? eHealthMe
4 hours ago Summary: Overall ratings: 3.2/5. Long term ratings: 3.5/5. This is a phase IV clinical study of how effective Flomax (tamsulosin hydrochloride) is for Urinary retention and for what kind of people. The study is created by eHealthMe from 42 Flomax users and is updated continuously. With medical big data and AI algorithms, eHealthMe enables
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Flomax, For, From
Tamsulosin for treatment of lower urinary tract symptoms
3 hours ago Tamsulosin has been used for the off-label treatment of lower urinary tract symptoms (LUTS) in women. Over the past few years, several randomized controlled …
Publish Year: 2017
Author: H L Zhang, Z G Huang, Y Qiu, X Cheng, X Q Zou, T T Liu
Website: Nature.com
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For, Few
Flomax (tamsulosin) dosing, indications, interactions
Just Now Monitor Closely (1) istradefylline will increase the level or effect of tamsulosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Istradefylline 40 mg/day increased peak levels and AUC of CYP3A4 substrates in clinical trials. This effect was not observed with istradefylline 20 mg/day.
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Tamsulosin (Flomax) Side Effects, Interactions, Uses
7 hours ago Tamsulosin is an alpha-blocker that is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate). Tamsulosin is not approved for use in women or children.
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For
Tamsulosin kidney stones women Answers from Doctors
9 hours ago Dr. Michael Kuglitsch answered. Urology 41 years experience. Flomax (tamsulosin) for stone: Flomax (tamsulosin) is often added to a patient with kidney stones to help the stone past. It has been effective in less than 24% in european study.
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Flomax, For
Flomax (tamsulosin hydrochloride) dose, indications
4 hours ago Tamsulosin is not indicated for use in women and there are no adequate data on the developmental risks associated with the use of tamsulosin during human pregnancy. Animals studies have not revealed adverse developmental effects; however, animal studies are not always predictive of human response.
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For
Ask an Expert: Flomax for women?
Just Now Flomax is the brand of a drug called tamsulosin. It is used to treat a medical problem in men called benign prostatic hyperplasia. The drug has been used “off label” for other medical problems which may effect men and women. An “off label” use of a drug means an unapproved use. In the United States, the Food and Drug Administration (FDA
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Flomax, For, Food, Fda
Flomax: Flomax for women Medications.com
7 hours ago Okf321 – I am a 38 year old female taking flomax for urinary retention (unable to empty bladder, trouble starting stream, stream stops after just a few seconds). Flomax has changed my life. I was trying to ‘go’ 20 times a day, and getting very frustrated. I now go only 6 or 7 times a day, with no trouble starting to go, and I am able to empty all the way without any problem.
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Female, Flomax, For, Few, Frustrated
Tamsulosin (Flomax) warnings: be aware of these issues
5 hours ago Tamsulosin side effects. Like all medications, tamsulosin has side effects that you should be aware of. Some common side effects of tamsulosin include headache, dizziness, common cold symptoms (like a runny nose or nasal congestion), diarrhea, drowsiness, and abnormal ejaculation (DailyMed, 2017). However, more serious side effects can occur
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Flomax Side Effects: The Good and Bad Update: November
Just Now While only approved for use in men, Flomax is often prescribed off-label for women. Doctors have prescribed the drug to help women pass kidney stones and to help with bladder outlet obstruction (BOO). Researchers only studied the medicine for its effect on the prostate so far; however, the thought is that it will also work on other receptors in
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For, Flomax, Far
DailyMed FLOMAX tamsulosin hydrochloride capsule
3 hours ago FLOMAX is a prescription alpha-blocker medicine used to treat the signs and symptoms of benign prostatic hyperplasia (BPH), a condition your doctor may refer to as an enlarged prostate. FLOMAX is not for women. FLOMAX is not for children. Who should not take FLOMAX? Do not take FLOMAX capsules if you are allergic to any of its ingredients.
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Flomax, For
Flomax®
5 hours ago FLOMAX (tamsulosin HCl) capsules are not intended for use as an antihypertensive drug. Pharmacokinetics The pharmacokinetics of tamsulosin HCl have been evaluated in adult healthy volunteers and patients with BPH after single and/or multiple administration with doses ranging from 0.1 mg to 1 mg. Absorption
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Flomax, For, From
How Effective Is Tamsulosin for Kidney Stones? (with pictures)
Just Now In women, taking tamsulosin is not effective for treating kidney stones. Recent medical studies have confirmed that giving male patients tamsulosin can effectively treat kidney stones. This drug works well when combined with extracorporeal shock wave lithotripsy (ESWL), a treatment that uses high-intensity sound waves for breaking kidney stones
Website: Thehealthboard.com
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For
Tamsulosin 0.4mg
9 hours ago 5.2 Drug Interactions. Tamsulosin is extensively metabolized, mainly by CYP3A4 and CYP2D6. Tamsulosin Hydrochloride Capsules 0.4 mg should not be used in combination with strong inhibitors of CYP3A4 (e.g., ketoconazole) [ see Drug Interactions and Clinical Pharmacology ].Tamsulosin Hydrochloride Capsules should be used with caution in combination with moderate inhibitors of …
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The Use of AlphaBlockers for the Treatment of Nephrolithiasis
3 hours ago Tamsulosin increases rates of spontaneous stone expulsion and decreases the time to stone expulsion (Tables 1 and and2). 2).Importantly, it decreases the amount of pain patients suffer while passing their stones (Table 3).Dellabella and colleagues 18 evaluated 60 patients with symptomatic ureterovesical junction stones. They compared 2 groups of 30 patients each: 1 group received tamsulosin
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Drug-Induced Urinary Incontinence
US Pharm. 2014;39(8):24-29.
ABSTRACT: Urinary incontinence affects both men and women, and especially the elderly. The Agency for Health Care Policy and Research identified four types of urinary incontinence: stress, urge, mixed, and overflow. Pharmacologic agents including oral estrogens, alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, nonsteroidal anti-inflammatory drugs, and calcium channel blockers have been implicated to some degree in the onset or exacerbation of urinary incontinence. The pharmacist should consider urinary incontinence–inducing drugs when reviewing patient profiles.
In healthy humans, voiding occurs at intervals several times a day, even though the kidneys produce urine continuously. This means that the bladder must store urine for several hours, a feature that requires the musculature of the bladder-outflow tract to contract to generate resistance. Disturbances of this storage function of the bladder lead to urinary incontinence. A number of factors may be responsible, including disease and adverse effects of medical treatment.1
A number of medications have been proposed as possible causes of drug-induced urinary incontinence, including alpha1-adrenoceptor antagonists, antipsychotics, benzodiazepines, antidepressants, and drugs used for hormone replacement therapy.1 Since drugs are frequently metabolized and excreted in the urine, the lower urinary tract is particularly vulnerable to adverse effects. Furthermore, carcinogens or inflammatory agents in the urine are in close proximity to the epithelium for prolonged periods when they are stored in the bladder. The drugs may cause stress incontinence, urge incontinence, or overflow incontinence.2
This article discusses the different types of incontinence, their causes, and the possible mechanisms underlying incontinence resulting from medications.
Epidemiology
The prevalence of urinary incontinence increases with age, with an overall prevalence of 38% in women and 17% in men. In women, the prevalence is about 12.5% in those aged 60 to 64 years and rises to about 20.9% in those aged ≥85 years. Furthermore, a higher prevalence has been noted in non-Hispanic white women (41%) compared with non-Hispanic black (20%) and Mexican-American women (36%).3 In a similar study, the prevalence of weekly incontinence was highest among Hispanic women, followed by white, black, and Asian-American women.4
In men, the prevalence increases with age, from 11% in those aged 60 to 64 years to 31% in those aged ≥85 years. The rate of incontinence in black men is similar to that for black women, but in white and Mexican-American men, the rate is 2.5 times lower than in women of the same ethnicity.3
Urinary incontinence may be underreported, owing to the embarrassing nature of the condition.
Types of Incontinence
According to the clinical practice guidelines issued by the Agency for Health Care Policy and Research (now called Agency for Healthcare Research and Quality), there are four types of incontinence: stress, urge, mixed, and overflow. Other guidelines identify functional incontinence as a fifth type.5-8TABLE 1 describes the various types of incontinence in more detail, along with the usual approaches used in the management of each.5-10
Mechanisms of Urinary Continence
In healthy individuals, the urinary bladder senses the volume of urine by means of distention. Distention of the bladder excites afferent A-delta fibers (and C fibers, in a pathologic condition) that relay information to the pontine storage center in the brain. The brain, in turn, triggers efferent impulses to enhance urine storage through activation of the sympathetic innervation of the lower urinary tract (hypogastric nerve). These impulses also activate the somatic, pudendal, and sacral nerves.1
The hypogastric nerves release norepinephrine to stimulate beta3-adrenoceptors in the detrusor and alpha1-adrenoceptors in the bladder neck and proximal urethra. The role of beta3-adrenoceptors is to mediate smooth-muscle relaxation and increase bladder compliance, whereas that of alpha1-adrenoceptors is to mediate smooth-muscle contraction and increase bladder outlet resistance.1 The somatic, pudendal, and sacral nerves release acetylcholine to act on nicotinic receptors in the striated muscle in the distal urethra and pelvic floor, which contract to increase bladder outlet resistance.1
Efferent sympathetic outflow and somatic outflow are stopped when afferent signaling to the brain exceeds a certain threshold. At this point, the parasympathetic outflow is activated via pelvic nerves. These nerves release acetylcholine, which then acts on muscarinic receptors in detrusor smooth-muscle cells to cause contraction. A number of transmitters, including dopamine and serotonin, and endorphins are involved in this process.1
Pharmacologic Agents That Cause Urinary Incontinence
A variety of drugs have been implicated in urinary incontinence, and attempts have been made to determine the mechanism responsible based upon current understanding of the processes involved in continence and the transmitters that play a role. Each of the processes described previously can be manipulated by pharmacologic agents to cause one or more types of incontinence.
The drugs commonly pinpointed in urinary incontinence include anticholinergics, alpha-adrenergic agonists, alpha-antagonists, diuretics, calcium channel blockers, sedative-hypnotics, ACE inhibitors, and antiparkinsonian medications. Depending upon the mode of action, the effect may be direct or indirect and can lead to any of the types of incontinence. Taking these factors into account, it is important to consider a patient’s drug therapy as a cause of incontinence, particularly in new-onset incontinence patients and in elderly patients, in whom polypharmacy is common.11,12
On the other hand, a pharmacologic agent or any other factor that results in chronic urinary retention can lead to a rise in intravesical pressure and a resultant trickling loss of urine. In this way, drugs that cause urinary retention can indirectly lead to overflow incontinence.2
Alpha-Adrenergic Antagonists: As described earlier, the stimulation of alpha1-adrenoceptors by norepinephrine leads to increased bladder outlet resistance. It has been shown that alpha1-adrenoceptors influence lower urinary tract function not only through a direct effect on smooth muscle, but also at the level of the spinal cord ganglia and nerve terminals. In this way, they mediate sympathetic, parasympathetic, and somatic outflows to the bladder, bladder neck, prostate, and external urethral sphincter.13 Blocking these receptors with such agents as prazosin, doxazosin, and terazosin would therefore lead to reduced bladder outlet resistance and, accordingly, to incontinence.2 One study found that the use of alpha-blockers increased the risk of urinary incontinence in older African American and white women nearly fivefold.14 Another study showed that almost half of female subjects taking an alpha-blocker reported urinary incontinence.15 Phenoxybenzamine, a nonselective, irreversible alpha-adrenoceptor antagonist, has been associated with stress urinary incontinence.1
It is useful to note that many antidepressants and antipsychotics exhibit considerable alpha1-adrenoceptor antagonist activity.1
Alpha-Adrenergic Agonists: Alpha-adrenergic agonists such as clonidine and methyldopa mimic the action of norepinephrine at receptors. In this way they may contract the bladder neck, causing urinary retention and thus overflow urinary incontinence.2,16-18
Antipsychotics: A number of antipsychotics have been associated with urinary incontinence, including chlorpromazine, thioridazine, chlorprothixene, thiothixene, trifluoperazine, fluphenazine (including enanthate and decanoate), haloperidol, and pimozide.19-24 Incontinence occurs over a broad range of antipsychotic dosages. Additionally, whereas some patients experience urinary incontinence within hours of initiating antipsychotic therapy, others do not experience incontinence for weeks after initiation. In most cases, the incontinence remits spontaneously upon discontinuation of the antipsychotic. Typical antipsychotics are primarily dopamine antagonists and lead to stress urinary incontinence, whereas atypical antipsychotics are antagonists at serotonin receptors.24 Antipsychotics also cause incontinence by one or more of the following mechanisms: alpha-adrenergic blockade, dopamine blockade, and cholinergic actions on the bladder.25 Owing to these complex drug-receptor interactions, a generalized description of how antipsychotics cause urinary incontinence cannot be given.1
If it is not possible to discontinue the antipsychotic, urinary incontinence caused by antipsychotics can be managed with a variety of pharmacologic agents. Desmopressin is perhaps the most effective, but also the most expensive, therapeutic agent available for this use. Other agents include pseudoephedrine, oxybutynin, benztropine, trihexyphenidyl, and dopamine agonists.25
Antidepressants: There are a number of classes of antidepressants, all with varying pharmacologic properties. This makes it difficult to generalize the underlying mechanisms that lead to urinary incontinence as a result of antidepressant use. However, all antidepressants result in urinary retention and, eventually, in overflow incontinence. Most antidepressants are inhibitors of norepinephrine and/or serotonin uptake. Some also act as antagonists at adrenergic, cholinergic, or histaminergic receptors at therapeutic doses.1
Diuretics: The purpose of a diuretic is to increase the formation of urine by the kidneys. As a result, diuretics increase urinary frequency and may cause urinary urgency and incontinence by overwhelming the patient’s bladder capacity. One study reported a link between diuretics and/or conditions associated with their use and urinary incontinence in community-dwelling women.26 In another study, the use of a loop diuretic with an alpha-blocker almost doubled the risk of urinary incontinence versus alpha-blockers alone, but no increased risk was noted when thiazide diuretics or potassium-sparing diuretics were added to the alpha-blockers.27
Calcium Channel Blockers: Calcium channel blockers decrease smooth-muscle contractility in the bladder. This causes urinary retention and, accordingly, leads to overflow incontinence.10
Sedative-Hypnotics: Sedative-hypnotics result in immobility secondary to sedation that leads to functional incontinence.10 Furthermore, benzodiazepines can cause relaxation of striated muscle because of their effects on gamma-aminobutyricacid type A receptors in the central nervous system.1,28
ACE Inhibitors and Angiotensin Receptor Blockers: The renin-angiotensin system exists specifically in the bladder and the urethra. Blocking angiotensin receptors with ACE inhibitors or angiotensin receptor blockers decreases both detrusor overactivity and urethral sphincter tone, leading to reduced urge incontinence and increased stress urinary incontinence.29 Furthermore, ACE inhibitors can result in a chronic dry cough that can cause stress incontinence. This was demonstrated in a female patient with cystocele who was receiving enalapril. The patient developed a dry cough and stress incontinence, which ceased within 3 weeks of discontinuing the ACE inhibitor.
Estrogens: One study showed that oral and transdermal estrogen, with or without progestin, increased the risk of urinary incontinence by 45% to 60% in community-dwelling elderly women.14 A summary of randomized, controlled trials also showed that the use of oral estrogen increased the risk of urinary incontinence by 50% to 80%.30
Hydroxychloroquine: Hydroxychloroquine has recently been identified as an agent that can induce urinary incontinence. There is currently only one report supporting this finding. In this report, a 71-year-old female patient developed urinary incontinence as an adverse reaction to hydroxychloroquine administered at therapeutic doses to treat rheumatoid arthritis. Urinary incontinence remitted with drug withdrawal and reappeared when the drug was readministered.31
Conclusion
A variety of drugs have been associated with urinary incontinence. This may be due to direct incontinence or overflow incontinence secondary to urinary retention. When reviewing patient profiles, pharmacists should take into consideration the use of oral estrogens, alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, nonsteroidal anti-inflammatory drugs, and calcium channel blockers that may lead to urinary incontinence. It is important to keep in mind that some incontinence patients taking these medications may be too embarrassed to discuss their condition voluntarily.
REFERENCES
1. Tsakiris P, Oelke M, Michel MC. Drug-induced urinary incontinence. Drugs Aging. 2008;25:541-549.
2. Drake MJ, Nixon PM, Crew JP. Drug-induced bladder and urinary disorders. Incidence, prevention and management. Drug Saf. 1998;19:45-55.
3. Anger JT, Saigal CS, Litwin MS; Urologic Diseases of America Project. The prevalence of urinary incontinence among community dwelling adult women: results from the National Health and Nutrition Examination Survey. J Urol. 2006;175:601-604.
4. Thom DH, van den Eeden SK, Ragins AI, et al. Differences in prevalence of urinary incontinence by race/ethnicity. J Urol. 2006;175:259-264.
5. Nazir T, Khan Z, Barber HR. Urinary incontinence. Clin Obstet Gynecol. 1996;39:906-911.
6. Chutka DS, Fleming KC, Evans MP, et al. Urinary incontinence in the elderly population. Mayo Clin Proc. 1996;71:93-101.
7. Gibbs CF, Johnson TM II, Ouslander JG. Office management of geriatric urinary incontinence. Am J Med. 2007;120:211-220.
8. Rogers RG. Clinical practice. Urinary stress incontinence in women. N Engl J Med. 2008;358:1029-1036.
9. American College of Obstetricians and Gynecologists. Urinary incontinence in women. Obstet Gynecol. 2005;105:1533-1545.
10. Vasavada SP. Urinary incontinence. Medscape. http://emedicine.medscape.com/article/452289-overview#showall. Accessed May 15, 2014.
11. Patel AK, Chapple CR. Urodynamics in the management of female stress incontinence—which test and when? Curr Opin Urol. 2008;18:359-364.
12. Curtis LA, Dolan TS, Cespedes RD. Acute urinary retention and urinary incontinence. Emerg Med Clin North Am. 2001;19:591-619.
13. Andersson KE, Lepor H, Wyllie MG. Prostatic alpha 1-adenoreceptors and uroselectivity. Prostate. 1997;30:202-215.
14. Ruby CM, Hanlon JT, Boudreau RM, et al; Health, Aging and Body Composition Study. The effect of medication use on urinary incontinence in community-dwelling elderly women. J Am Geriatr Soc. 2010;58:1715-1720.
15. Marshall HJ, Beevers DG. Alpha-adrenergic blockade and urinary incontinence. J Hypertens. 1993;11:1152-1153.
16. Raz S. Adrenergic influence on the internal urinary sphincter. Isr J Med Sci. 1974;10:608-611.
17. Kleeman FJ. The physiology of the internal urinary sphincter. J Urol. 1970;104:549-554.
18. Fernandez PG, Sahni S, Galway BA, et al. Urinary incontinence due to interaction of phenoxybenzamine and alpha-methyldopa. Can Med Assoc J. 1981;124:174-175.
19. Ambrosini PJ, Nurnberg HG. Enuresis and incontinence occurring with neuroleptics. Am J Psychiatry. 1980;137:1278-1279.
20. Shapiro AK. Pimozide-induced enuresis. Am J Psychiatry. 1981;138:123-124.
21. Kiruluta HG, Andrews K. Urinary incontinence secondary to drugs. Urology. 1983;22:88-90.
22. Ambrosini PJ. A pharmacological paradigm for urinary incontinence and enuresis. J Clin Psychopharmacol. 1984;4:247-253.
23. Van Putten T, Malkin MD, Weiss MS. Phenothiazine-induced stress incontinence. J Urol. 1973;109:625-626.
24. Fuller MA, Borovicka MC, Jaskiw GE, et al. Clozapine-induced urinary incontinence: incidence and treatment with ephedrine. J Clin Psychiatry. 1996;57:514-518.
25. Clark N. Conventional antipsychotic and clozapine-induced urinary incontinence. JCPNP. 2003:2(2). https://cpnp.org/_docs/resource/jcpnp/urinary-incontinence.pdf. Accessed May 19, 2014.
26. Fantl JA, Wyman JF, Wilson M, et al. Diuretics and urinary incontinence in community-dwelling women. Neurourol Urodyn. 1990;9:25-34.
27. Peron EP, Zheng Y, Perera S, et al; Health, Aging, and Body Composition (Health ABC) Study. Antihypertensive drug class use and differential risk of urinary incontinence in community-dwelling older women. J Gerontol A Biol Sci Med Sci. 2012;67:1373-1378.
28. Landi F, Cesari M, Russo A, et al. Benzodiazepines and the risk of urinary incontinence in frail older persons living in the community. Clin Pharmacol Ther. 2002;72:729-734.
29. Elliott CS, Comiter CV. The effect of angiotensin inhibition on urinary incontinence: data from the National Health and Nutrition Examination Survey (2001–2008). Neurourol Urodyn. August 29, 2013 [Epub ahead of print].
30. Shamliyan TA, Kane RL, Wyman J, Wilt TJ. Systematic review: randomized, controlled trials of nonsurgical treatments for urinary incontinence in women. Ann Intern Med. 2008;148:459-473.
31. Carnovale C, Perrone V, Borsadoli C, et al. A case of urinary incontinence by hydroxychloroquine in a geriatric patient. J Clin Pharm Ther. 2013;38:169-171.
To comment on this article, contact [email protected].
Flomax | Healthgrades | (tamsulosin hydrochloride capsule)
Brand Name: Flomax
Generic Name: TAMSULOSIN HYDROCHLORIDE
Drug Type: HUMAN PRESCRIPTION DRUG
Route: ORAL
Dosage Form: CAPSULE
Data Current As Of: 2019-09-02
FLOMAX (tamsulosin hydrochloride, USP) capsulesare indicated for the treatment of the signs and symptoms of benignprostatic hyperplasia (BPH) [ see Clinical Studies (14) ]. FLOMAX capsulesare not indicated for the treatment of hypertension.
- FLOMAX is an alpha1 adrenoceptorantagonist indicated for treatment of the signs and symptoms of benignprostatic hyperplasia (1)
- FLOMAX capsules are not indicated for the treatment of hypertension (1)
patient counselinginformation
Advise thepatient to read the FDA-approved patient labeling (Patient Information)
Hypotension
Advise the patient aboutthe possible occurrence of symptoms related to postural hypotension,such as dizziness, when taking FLOMAX capsules, and they should becautioned about driving, operating machinery, or performing hazardoustasks [ see Warnings and Precautions (5.1) ].Drug Interactions
Advise the patientthat FLOMAX should not be used in combination with strong inhibitorsof CYP3A4 [see Warnings and Precautions (5.2) and Drug Interactions (7.1)].Priapism
Advise the patient aboutthe possibility of priapism as a result of treatment with FLOMAX capsulesand other similar medications. Patients should be informed that thisreaction is extremely rare, but if not brought to immediate medicalattention, can lead to permanent erectile dysfunction (impotence)[ see Warnings and Precautions (5.3) ].- Screening for Prostate Cancer
Prostatecancer and BPH frequently co-exist; therefore, screen patients forthe presence of prostate cancer prior to treatment with FLOMAX capsulesand at regular intervals afterwards [see Warnings and Precautions(5.4)]. Intraoperative Floppy Iris Syndrome
Advise the patient when considering cataract or glaucoma surgeryto tell their ophthalmologist that they have taken FLOMAX capsules[ see Warnings and Precautions (5.5) ].- Administration
Advise the patientthat FLOMAX capsules should not be crushed, chewed or opened [see Dosage and Administration (2)].
FDA-approved PatientLabeling
Patient labeling is provided as a tear-offleaflet at the end of this prescribing information.
Distributed by:
Boehringer Ingelheim Pharmaceuticals, Inc.
Ridgefield,CT 06877 USA
FLOMAX is a registeredtrademark of, and licensed from:
Astellas Pharma Inc.
Tokyo 103-8411, JAPAN
Copyright© 2016, ALL RIGHTS RESERVED
IT6314BA212016
2000007096
PATIENTINFORMATION
FLOMAX® (Flō-max)
(tamsulosin hydrochloride,USP)
Capsules, 0.4 mg
Read the Patient Information that comes with FLOMAXcapsules before you start taking it and each time you refill yourprescription. The information may have changed. This leaflet doesnot take the place of discussions with your doctor about your medicalcondition or your treatment.
What is FLOMAX?
FLOMAXis a prescription alpha-blocker medicine used to treat the signs andsymptoms of benign prostatic hyperplasia (BPH), a condition your doctormay refer to as an enlarged prostate.
- FLOMAX is not for women.
- FLOMAX is not for children.
Who should not takeFLOMAX?
Do not take FLOMAX capsules ifyou are allergic to any of its ingredients. See the end of this leafletfor a complete list of ingredients in FLOMAX capsules.
What should I tell my doctorbefore using FLOMAX?
- Before taking FLOMAX capsules,tell your doctor about all your medical conditions, including:
- any kidney or liver problems.
- any history of low blood pressure.
- any allergies to sulfa or any other medicines.
- if you are planning to have cataract or glaucoma surgery.
Tell your doctorabout all the medicines you take, including:
- any prescription medicines, including blood pressure medicines.
- any non-prescription medicines, including vitamins and herbalsupplements.
Some of your other medicines mayaffect the way FLOMAX capsules work. Especially tell your doctorif you take a medicine for high blood pressure. You should not takeFLOMAX if you are already taking certain blood pressure medicines.
Know the medicines you take. Keepa list of them and show it to your doctor and pharmacist when youget a new medicine.
How should I take FLOMAX?
- Take FLOMAX exactly as prescribed by your doctor.
- Do not crush, chew, or open FLOMAX capsules.
- Take FLOMAX one time each day, about 30 minutes after thesame meal each day. For example, you may take FLOMAX 30 minutes afterdinner each day.
- If you miss a dose of FLOMAX, take it as soon as you remember. If you miss your dose for the whole day, continue with your nextdose on your regular schedule. Do not take two doses at the sametime.
- If you stop or forget to take FLOMAX for several days, talkwith your doctor before starting again.
- If you take more FLOMAX capsules than prescribed, call yourdoctor right away.
What are the possibleside effects of FLOMAX capsules?
Possibleside effects of FLOMAX may include:
- Decreased blood pressure when changing positions. FLOMAX capsules may cause a sudden drop in blood pressureupon standing, especially after the first dose or when changing doses.
Symptoms may include:Change positions slowly from lyingdown to sitting up or from a sitting to a standing position untilyou learn how you react to FLOMAX capsules. If you begin to feel dizzy,sit or lie down until you feel better. If the symptoms are severeor do not improve, call your doctor.
- Allergic reactions. Makeyour doctor aware of any allergic reactions you may experience whiletaking FLOMAX.
Allergic reactions may include:Rare and more serious allergic reactions may also occur. Get medical help right away if you have any of the followingreactions:
- swelling of face, tongue, or throat
- difficulty breathing
blistering of the skin
A painful erection that will not go away. FLOMAX capsules can cause a painful erection (priapism),which cannot be relieved by having sex. If this happens, get medicalhelp right away. If priapism is not treated, you may not be ableto get an erection in the future.
- Eye problems during cataract or glaucomasurgery. During cataract or glaucoma surgery, acondition called intraoperative floppy iris syndrome (IFIS) can happenif you take or have taken FLOMAX capsules. If you need to have cataractor glaucoma surgery, be sure to tell your surgeon if you take or havetaken FLOMAX capsules.
Common side effects of FLOMAX capsulesmay include:
These are not all the possible sideeffects with FLOMAX capsules. Tell your doctor if you have any sideeffect that bothers you or that does not go away.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088, or by visitingwww.fda.gov/medwatch.
What should I avoid while taking FLOMAX capsules?
Avoid driving, operating machinery, or other dangerousactivities, until you know how FLOMAX affects you. FLOMAX capsulesmay cause a sudden drop in blood pressure upon standing, especiallyafter the first dose or when changing doses. See ” What are the possible side effects of FLOMAX capsules? “
Howdo I store FLOMAX capsules?
Store FLOMAXcapsules at Room Temperature [77°F (25°C)]. Short-term exposure tohigher or lower temperatures [from 59°F (15°C) to 86°F (30°C)] isacceptable. Ask your doctor or pharmacist if you have any questionsabout storing your capsules.
Keep FLOMAX capsules and all medicines out of thereach of children.
General information
This medicine was prescribed for you by your doctor foryour condition. Do not use it for another condition. Do not giveFLOMAX to other people, even if they have the same symptoms that youhave. It may harm them.
Whiletaking FLOMAX, you must have regular checkups. Follow your doctor’sadvice about when to have these checkups.
BPH can occur with other more serious conditions, includingprostate cancer. Therefore, ask your doctor about screening for prostatecancer prior to treatment with FLOMAX capsules and at regular intervalsafterwards.
This patient informationleaflet summarizes the most important information about FLOMAX. Ifyou would like more information, talk with your doctor. You can askyour pharmacist or doctor for information about FLOMAX that is writtenfor health professionals. For current prescribing information scanthe code below, or call Boehringer Ingelheim Pharmaceuticals, Inc.at 1-800-542-6257, or (TTY) 1-800-459-9906.
What are the ingredientsin FLOMAX capsules?
- Active Ingredient: tamsulosin hydrochloride, USP
- Inactive Ingredients: microcrystalline cellulose; methacrylicacid copolymer dispersion; triacetin; calcium stearate; talc; gelatin;iron oxide; FD&C blue No. 2; titanium dioxide; propylene glycol;and shellac.
Distributed by:
BoehringerIngelheim Pharmaceuticals, Inc.
Ridgefield, CT 06877 USA
FLOMAX is a registered trademark of, andlicensed from:
Astellas Pharma Inc.
Tokyo 103-8411,JAPAN
Copyright © 2016, ALL RIGHTSRESERVED
IT6314BA212016
2000007096
Revised:January 2016
Flomax
(tamsulosin hydrochloride,USP)
0.4 mg
100 capsules
NDC: 0597-0058-01
- tamsulosin hydrochloride (capsule)
90,000 flax seeds for women. Benefit and harm
A large number of amino acids, proteins, various vitamins and minerals – a short list of the beneficial properties of flax seeds. “A plant with a thousand-year history” – this is what scientists say about it, while adding that with the constant use of its seeds, you can protect yourself from serious diseases. The seeds protect against cardiovascular disease, lower blood pressure and cholesterol, and protect the walls of arteries from the formation of blood clots and plaques. Flax seeds are also useful for those who are going to lose weight.The fact is that they contain vitamins B1, B2, B9, which convert fats and carbohydrates into energy, improve metabolism. Also, the seeds act as a natural sorbent that removes toxins, help with digestive disorders. For example, the fiber in seeds is food for beneficial bacteria and helps to get rid of toxins.
For various problems with the gastrointestinal tract, it is recommended to drink tinctures. For digestive disorders: add 2 tbsp. tablespoons of seeds in 350 ml of boiled water.Let it brew and take 100 ml of drink before meals. And in case of constipation, you must first soak 4-6 teaspoons of seeds in water and take 2 tablespoons several times a day with plenty of liquid.
Flax seeds are also excellent for diseases such as low immunity, poisoning, bronchitis, pneumonia, oral problems, acne, psoriasis, varicose veins, atherosclerosis. The list can be continued for a long time, but nevertheless it is better not to self-medicate, but to seek medical advice, because there is a whole list of contraindications.For example, excessive consumption can lead to diarrhea and poor blood clotting. You can not eat flaxseed and people with acute inflammation of the gastrointestinal tract, women with polycystic disease, uterine fibroids, men with prostate problems and patients with diabetes mellitus.
The average rate of flax seeds per day is 30-40 grams. To strengthen the immune system, the product can be taken dry, chewed and washed down with water (a teaspoon per day is enough). For weight loss, pour a teaspoon of seeds with kefir or yogurt and let it brew.Take this mixture once a day between lunch and dinner. It is very important to adhere to the course scheme: 1 week – 1 spoon per glass of kefir, 2 week – 2 spoons per glass, 3 week – 3 spoons. Then a break for 2 weeks.
Seeds are also used in cosmetology. For example, a hair lotion is prepared very simply: pour 10 g of seeds with boiling water (100 ml), allow to cool, strain and apply to the hair. You can now buy such seeds in regular stores, as well as in health food stores or in pharmacies.
Read more about healthy nutrition:
Why flax seeds are useful for women
Flax has important and necessary characteristics for maintaining the health of any organism. But flax seeds are especially useful for women.
The therapeutic advantage of flax is determined by its composition, which includes omega-3 fatty acids (the body does not produce them on its own and needs external sources) and natural hormones lignans. The latter block the action of harmful estrogens that provoke malignant neoplasms in the breast.
Flax promotes weight loss
Flaxseeds remove toxins, carcinogens and bad cholesterol, promote rapid absorption of food and are very beneficial for the intestines.
It is useful to use them for breakfast in combination with kefir, this will provide resistance to pathogenic bacteria. Such a nutritional complex gives a feeling of fullness for a long time and saves from overeating.
Flax seeds for women during and after pregnancy
For women expecting a baby, flaxseed fiber will help get rid of the inevitable bloating and constipation, and will protect those who have given birth from postpartum depression.This is facilitated by vitamins B and lecithin – well-known protectors of the nervous system.
Food Forms of Flax
How and When to Take Flax Seeds
Nutritionists advise eating flaxseeds in the morning: add them to porridge, yogurt or cereals. Flax is very useful to combine with fermented milk products: kefir, cottage cheese, yogurt.
To cleanse the body, boil flax and drink a jelly-like liquid on an empty stomach for several days in a row. The broth is prepared like this: pour 1 tbsp.l. flax seeds with boiling water, hold on low heat for about 30 minutes, then leave them to steam in a warm place (under a blanket or woolen clothes). The daily rate is no more than 250 ml.
Contraindications to use
Flax is not always beneficial. For people with hypercalcemia, seeds can be harmful because they contain a lot of calcium.
Seeds become harmful if stored improperly. The product should be kept in a cool, dark place, and under no circumstances should it be left in direct sunlight.At high temperatures, oils and fatty acids oxidize and form carcinogenic peroxides. If the seeds are bitter, they can no longer be consumed.
The recipe uses flaxseed fiber of the brand Zemledar ™ , which is made from natural flax seeds grown without agrochemistry on the day of order. It is recommended to use it for both dietary and therapeutic and prophylactic purposes. You can go to the website of the company Zemledar ™ and place an order.90,000 Flax seeds: benefits and contraindications
Flax seeds: Pixabay
Flax seeds, the benefits of which have been proven by traditional medicine, are increasingly recommended by doctors as a dietary supplement to many categories of people. Among them are residents of contaminated regions, people with chronic diseases and those who want to lose weight. Let’s figure out what the harm and benefits of flaxseed are.
Flax Seeds: Benefits for Women and Men
Flax is a fibrous crop that provides us with healthy seeds.Phytoestrogens and oils in the composition are of great benefit to the body.
Flax brown and golden yellow is indispensable for the skin and the body as a whole. It is a common dietary supplement that has recently been seen on supermarket shelves. There are seed meal and oil, which is used in salads, used for cosmetic procedures.
Why are flax seeds useful? What properties does flaxseed have? Why has its use become so widespread? The answers to these questions are contained in the composition of this herbal product.A set of unique amino acids, vitamins, fiber and fatty acids make flaxseed a unique dietary remedy, which is used in various fields – health improvement, proper nutrition, cooking and cosmetology.
Are you considering whether to use flaxseed? The beneficial properties of the product have been confirmed by many of my colleagues. Verena Tan, MD, writes more about this in an article for Healthline. Despite this, I do not recommend making an independent decision on the application of the product.Consult a doctor beforehand.
Flax seeds have the following valuable properties:
- They cleanse the body of toxins, promote the elimination of waste products of harmful bacteria. They are used for anthelmintic prophylaxis.
- Improve the functioning of the digestive tract, create a feeling of satiety, envelop the stomach. Therefore, flax seeds are used for weight loss.
- Pectin and fiber bind heavy metals and remove them from the body.
- Strengthen blood vessels, break down cholesterol plaques.
- Replenish the body with selenium and potassium. Their lack leads to the oncological and cardiovascular diseases, edema develops, and heart rhythm disturbances occur.
- Why are flax seeds useful for women? B vitamins strengthen the nervous system and have a special effect on the female body: they reduce pain and relieve tension during PMS, help to recover faster after termination of pregnancy, relieve unpleasant symptoms during menopause.
- Vitamin B1, found in excess in flax seeds, lowers blood sugar levels.Diabetics are advised to take such meal.
- Flaxseeds, rich in minerals and trace elements, are actively used in cosmetology: decoctions, masks, infusions for washing hair, etc. are prepared from them.
These healing qualities have been known since ancient times. Charlemagne, by special decrees, ordered his subjects to regularly consume flaxseed, the properties of which have a positive effect on the body. Mahatma Gandhi argued that humanity will become healthier if it understands the benefits of flax.
Flax Seeds: Pixabay
When choosing, buying and using a plant-based product, I recommend listening to certain rules. When purchasing flaxseed, the use of which is due to the beneficial effect, avoid raw and unripe kernels. These may contain toxic compounds. Also:
- When using linseed oil, keep in the refrigerator in dark bottles. Do not use it after the expiration date.
- Do not heat oil while cooking. Add it to ready-made meals.
Have you bought flax seeds? How to take the product:
- Sprinkle the seeds on salads and other dishes.
- Add whole and ground to yoghurts and smoothies.
- Use grains in baked goods, baked goods, bread.
- Use as a breading for cutlets and other dishes.
Remember to use flaxseed on an empty stomach with caution. According to research, a normal dose is 1 tablespoon (10 g) of ground flaxseed per day.It is the crushed product that is easier to digest and absorb by the body. In this case, it is better to ask your doctor about the exact dosage. Remember that self-medication can lead to serious consequences for the body.
It is best to grind the seeds yourself in a coffee grinder and store in an airtight container. I recommend that you read the WebMD review on the use and effects of flax on the body.
Flax seeds: harm and contraindications
Before taking flax seed, the benefits and harms for women and men of which have been proven on the example of many people, it is worth learning more about the side effects.And they are, as in any other product.
If you are thinking about introducing this product into your diet, ask what harm flax seeds can cause:
- If you take more than one tablespoon of the product a day, you can harm the liver, which will be difficult to cope with the breakdown of flaxseed oil.
- Overdose can lead to flatulence and diarrhea. Therefore, people with similar problems should be wary of the product.
- Possible intestinal blockage if flaxseed is overused.The use of the product is due to the correct dosage and the abundance of liquid. Otherwise, bowel obstruction and stool problems are likely.
- Possible manifestations of allergic reactions. These are shortness of breath, low blood pressure, nausea, and abdominal pain.
- May cause cholelithiasis and urolithiasis.
- Probably a change in the menstrual cycle in women, as the product mimics the action of estrogen. The hormonal state may change, which is subsequently fraught with infertility.
- Drug reactions may occur. The suction effect of the seeds can block the action of the drugs, so consult your doctor first.
Flax seeds: Pixabay
In this regard, I do not recommend using flax seeds as a dietary supplement for people:
- patients with cholecystitis, colitis; 90,074 90,073 for those with renal impairment;
- with intestinal obstruction;
- during pregnancy and lactation (due to possible allergic manifestations in the baby).
Practical experience proves that the benefits of flax seeds are not available to everyone, especially if the dosage is incorrect. For more information, see Dr.Katie Warwick’s review for MedicalNewsToday. This knowledge will help you avoid mistakes when using flax seed. The benefits of flax seeds are individual for each organism. Therefore, I recommend discussing the contraindications and benefits specifically for you with your doctor.
Flax seeds are an effective remedy that can improve the functioning of the digestive, hormonal and cardiovascular systems.They ensure the recovery of the body after exposure to an aggressive environment, malnutrition, stress.
Some of my patients have tried flaxseed. Reviews of the product are very different both from patients and from people on the web. Check out some of them in the photo:
Reviews: Irecommend / Hannah Banana Reviews: Irecommend / Tiana Medova
Of course, flax is a plant that gives us the opportunity to improve health and saturate the body with healthy fats, vitamins, and fiber.But do not self-medicate, or at least exceed the recommended dosage. If you notice negative effects on the body, then stop using the product.
However, flax seeds, the benefits and harms of which are discussed in the article, are not an elixir of life and not a panacea for all diseases. Therefore, take responsibility for its use, study all contraindications in order to avoid deterioration of the condition.
Attention! The material is for informational purposes only.You should not resort to the treatments described in it without first consulting your doctor.
Sources:
- Verena Tan. Top 10 Health Benefits of Flax Seeds // Healthline. – 2017. – April 26. – Available at: https://www.healthline.com/nutrition/benefits-of-flaxseeds
- Kathy W. Warwick. How healthful is flaxseed? // MedicalNewsToday. – 2020 .– 9 January. – Access mode: https://www.medicalnewstoday.com/articles/263405#nutrition
- Flaxseed.Review // WebMD. – Access mode: https://www.webmd.com/vitamins/ai/ingredientmono-991/flaxseed#
Author: Candidate of Medical Sciences Anna Ivanovna Tikhomirova
Reviewer: Candidate of Medical Sciences, Professor Ivan Georgievich Maksakov
Original article: https://www.nur.kz/food/healthy-eating/1727632-semena-lna-polza-i-vred/
90,000 useful properties and contraindications.How to take to cleanse the body?
Delicious tortillas can be baked from a mixture of flax and wheat flour. Cold pressed linseed oil has found its application in cooking, medicine and cosmetology. Bran, which, due to its low calorie content, often serves as a dietary product, is also produced. All this is due to the special properties of the plant.
In our article we will talk about the features of using flaxseed, its dangers and benefits, how to use it to cleanse the body and lose weight, and in what form it is better to take it.
Flax Seeds
They have long been recognized as a valuable nutritional supplement and versatile medicine for various ailments. They include:
- Insoluble coarse fiber. It helps to cleanse the intestines from various harmful substances: salts of heavy metals, radionuclides, carcinogens, etc. It improves gastrointestinal motility, helps to restore healthy microflora.
- Polyunsaturated acids.These substances are used for the treatment and prevention of various diseases of the heart and blood vessels: ischemia, hypertension and others. They help to improve the condition of the dermis and hair, and help to normalize weight. To meet the daily requirement for one of the acids (Omega-3), an incomplete art. spoons of grains.
- Lignan. It has antifungal, antiviral, and antibacterial properties. Moreover, it is an excellent antioxidant. Its effect is similar to the hormone estrogen, which has an anti-sclerotic effect, regulates smooth muscle tone, and helps restore the health of microcirculation in tissues.For women, the lignans contained in flaxseed are especially beneficial in reducing the likelihood of breast cancer.
- Soluble Fiber. Binds fatty acids, reducing their absorption. Thanks to this, it normalizes blood cholesterol levels and reduces the likelihood of atherosclerosis.
- Tocopherol (E). This vitamin has a good effect on the functioning of the digestive, immune, lymphatic and urinary systems. Provides an improvement in the appearance of hair and skin.Promotes the restoration of healthy hormonal levels.
- Vitamin F, which consists of unsaturated fatty acids that are not produced in the human body and are irreplaceable. It affects the metabolism. Provides anti-inflammatory and antihistamine effects. Stimulates the immune system. Promotes the normalization of fat metabolism in tissues.
- Vitamins of group C, K, B, PP and choline, macro- and microelements, including: potassium, sodium, phosphorus, iron, calcium, selenium, manganese, and others.This vitamin and mineral composition provides a positive effect on the functioning of all body systems.
Flax seed: medicinal properties and contraindications
Official and traditional medicine uses this product in the treatment of a large number of diseases and pathologies. Let’s take a closer look at the use of flax seeds and what they treat.
- Grains are useful as a coating agent for stomach ulcers, inflammation of the mucous membranes of the stomach, colon and small intestine.
- They are useful for chronic constipation as a mild laxative.
- Their mucus is used for hemorrhoids and rectal inflammation.
- Infusions are used to treat pyelonephritis and other diseases of the urinary tract.
- The remedies with this product help in case of respiratory system and throat ailments. Relieves dry cough.
- Various infusions or just grains can be used to cleanse the liver and intestines, if their work is disrupted.
- A large amount of soluble fiber, and its property to envelop the intestinal walls, reducing the absorption of fats and sugar, make flax an effective drug in diseases of the cardiovascular system and in the case of diabetes mellitus.
- Infusions will help to restore microcirculation in tissues. They help to reduce the number of internal edema.
- Flax is a prophylactic product for oncological diseases, including breast cancer.
- The product helps in case of vitamin deficiency, to restore immunity and as a means to cleanse the body and lose weight.
- Its use has a positive effect on hormones in women.
- It has antiparasitic properties, and will be useful if necessary to cleanse the intestines from parasites.
- Grains boiled in milk are used for heel spurs.
- When used carefully and carefully at dosage, it may be beneficial during pregnancy. The abundance of vitamins and minerals, as well as lignan, have a positive effect on the gestation process and the condition of the fetus.
Contraindications
Although this product has a wide range of uses, it also has contraindications and unpleasant side effects. If the dosage of this agent is exceeded, diarrhea, flatulence and problems with blood clotting may occur.
- In case of cholelithiasis and cholecystitis, various flax products should be used only after consulting a doctor. Since in the presence of stones in the gallbladder, muscle contraction can cause pinching of the stone and colic.
- Grains should be used with caution during pregnancy and lactation. Flax activates the intestines, which can cause an increase in the tone of the uterus and lead to miscarriage.
- Do not use oil and seeds internally with poor blood clotting, as well as in case of bleeding caused by polyps.
- Do not take this product if you have allergies or individual intolerances.
- If you are undergoing treatment with any medication, check the use of flax with your doctor.Since the fiber contained in it can interfere with the full effect of the drug.
Also, taking this remedy should be started only after consulting a doctor in the case of:
- Endometriosis, polycystic, uterine fibroids in women
- Diseases of the prostate gland in men.
- Acute inflammatory processes in the digestive tract.
- Exacerbation of inflammation of the gallbladder or pancreas.
- Intestinal obstruction.
Flax seed application
The daily intake of these grains for an adult weighing about 70 kg is 24 g. Although some nutritionists claim that this dose can be increased to 40 g per day. If you prefer to use flaxseed oil, then it is better to take it one tbsp. spoon in the morning or evening.
If you use flax in the form of bran or grains, then you need to drink them.And also drink about 2 liters of clean water daily to avoid constipation. Depending on the desired result, flax seeds can be eaten, drunk decoctions and infusions in the morning on an empty stomach or in the evening, or taken in accordance with recipes. It is better to limit the period of use to 3 weeks per month.
In what form is it better to take flax seeds: oil, bran or dry
Flax can be found in the following forms:
- Oil.
- Bran.
- Flour.
- Seeds.
Each of these products has its own pros and cons, as well as the area of the most effective application.
Bran is low in calories, and will be useful for weight loss. Like other types of fiber, they help cleanse the body, normalize the digestive, circulatory, and excretory systems. But since the main nutrients are contained in the core, crushed or whole grains are most useful for the body to prevent vitamin deficiency.A good option in this case would be bran additional additives. For example, Di & Di Corporation offers amaranth bran in a composition that contains flaxseed flour.
For example, if you need to compensate for a lack of Omega-3, it will be most effective to take the product in the form of cold-pressed oil. But in this case, you must follow the rules of its storage, and do not use it for frying, since when heated, the substances you need are destroyed.
The oil has ample opportunities for external use: as a basis for massage, for masks, in the treatment of various injuries of the skin.
Flour is also useful. If made from whole grains, it will be as effective as the original product. It is most convenient to use and add to dishes. But since heat treatment destroys some beneficial compounds, the effectiveness of such food for weight loss will be lower than in other cases.
How to take flax seeds to cleanse the intestines
Brew in a thermos or other suitable container 1 tbsp.a spoonful of grains with 1 mug of boiling water. And insist 3-4 hours (and longer). The resulting drink should be consumed along with the seeds, without straining. Duration of admission is 20 days. Break for 30 days. Then the process is repeated if necessary.
You can take flax seeds with kefir to cleanse the intestines. Cleaning is carried out according to the following scheme. During the first seven days in the morning on an empty stomach they drink 1 teaspoon of ground grains together with 100 ml of kefir. In the second week in the morning they eat 2 tsp.tablespoons of grains with the same amount of kefir. During the third and, if necessary, the fourth week in the morning they eat 3 teaspoons of the product and wash down with 150 ml of kefir. This recipe not only helps to cleanse the body, but also restores healthy microflora.
Flax seeds for gastritis
To relieve the symptoms of gastritis, such as heartburn, nausea and pain, infusions, decoctions and jelly with flaxseed are used.
There are many recipes for these drinks.Here are a few of them:
- Take 2 st. tablespoons of grains without impurities. Pour in one liter of hot water and leave in a thermos or other closed container wrapped in a towel overnight. This infusion is drunk one glass at a time before meals.
- Pour 20 g of beans with hot water (1l). Insist for 5 hours. Then strain. Drink 100-150 ml before meals.
- Take 1 tbsp. a spoonful of grains and pour boiling water (0.5 l).Insist for an hour, stirring occasionally, and then strain through a strainer. Take the resulting liquid in a glass twice a day on an empty stomach 15 minutes before meals. Duration of admission from 3 weeks to several months.
Drinks based on flax and kefir will also be effective.
Flax seed for women: benefits and harms
Flaxseeds are especially good for women because they contain lignin, which is a plant analog of the hormone estrogen.It has a positive effect on the state of the endocrine system, protects against breast cancer, helps restore healthy hormonal balance and alleviates the symptoms of menopause. It is also useful for menstruation, reducing unpleasant symptoms and mood swings.
Do not forget about using this product for cleansing the body and losing weight.
Flaxseed seeds are popular in cosmetology. It is used both naturally and as an oil.
Butter:
- Used as a base for massage.
- It is applied to the skin to treat acne, ulcers, wounds and other injuries.
- Rubbing it into your head half an hour or an hour before washing will strengthen your curls and make them more luxuriant.
- A mask made from a mixture of oil and glycerin, which is applied at night and washed off in the morning, will also be useful to strengthen the hair.
There are many formulations from flax seeds that have a good effect on the condition of the dermis and hair:
- If you have dry or sensitive skin, the following mask can be applied.Brew one tbsp. a spoonful of grains in 200-300 ml of boiling water. Place in a water bath and heat them over low heat for 15 minutes. Then strain the liquid. Apply the resulting mucus on your face for half an hour, and then rinse with warm water. You can add heavy cream or nourishing cream to the mucus. In this case, the composition is suitable even for the skin around the eyes.
- Brew one tbsp. a spoonful of flax seeds in 1 liter of boiling water, leave for 10-12 hours, strain the resulting liquid, use it as a rinse aid.
Flax seeds for weight loss and detoxification: how to take
For this product to help you in the difficult fight against excess weight, it must be taken correctly. If you use it in the form of bran or individual grains, remember to drink them, and consume at least 2 liters of clean water daily. Otherwise, fiber will not be able to swell in the stomach, and flaxseeds simply will not have the desired effect.
According to experts, in order to lose weight with flax grains, they must be crushed before taking.Pre-soaking, on the other hand, is not recommended.
It is ineffective to use flax or flour from it for baking, since preliminary heat treatment destroys many nutrients, and the dish will be of little use for weight loss.
But you can use this product as an additive to cereals, salads, as well as with honey, yogurt or kefir. For example, pour a few teaspoons into liquid berry jelly, and the resulting mass after swelling will perfectly saturate and help cleanse the body.
Recipes with flaxseed
Porridge
Such a dish will be especially useful for women, it will not only help to reduce weight, but also have a rejuvenating effect. Doctors recommend using such products during menopause or hormonal disorders. Also, such food is useful for respiratory diseases, diabetes mellitus, diseases of the digestive tract, genitourinary system, blood vessels and heart.
- Whole grains without additives are used for cooking.They are thoroughly washed and then poured with cold water 1.5–2 centimeters above the cereal level. And they leave it in a dark place for 10-12 hours. Before use, add salt and other spices, and beat with a whisk until foam appears.
- 2 st. moisten tablespoons of seeds with water. Boil 100 g of oatmeal with boiling water and leave to infuse. Add swollen, berries or fruits to the oatmeal to taste. You can also add some honey to the dish.
- You will need: 2 teaspoons of flour (flaxseed), dried apricots or figs 6-8 pieces, honey.Pour half a glass of cold water over the flour. Soak figs or dried apricots in the same amount of water. Leave it overnight. Stir the infusions in the morning and add 1 tbsp. a spoonful of honey.
- 2 teaspoons of flax flour, pour half a glass of cold water, and leave overnight. In the morning add ground sesame seeds, plums, 1 teaspoon of honey to the infusion.
Kissel
- Place any washed and cut fruit, berries or dried fruit in boiling water. Boil them for 10 minutes.and then add the grains. For 1 liter of liquid, st. a spoonful of seeds. Keep on fire for another 5-10 minutes, then remove from the stove and leave. During the cooking process, mucus is released from it, which will turn the drink into jelly.
- In one glass of water, thoroughly stir 25 g of flour. Then it is poured into a saucepan, brought to a boil and left over low heat for 2-3 minutes. The resulting drink is added with sugar or honey. It is better to drink it before bedtime or in the morning on an empty stomach.
Salad
- Pour 1.5 h.tablespoons of grains with cold water (½ cup) and leave for 10-12 hours. Add orange slices, grated apple, cut prunes and figs (3-4 pieces), 1 teaspoon of lemon zest, honey and coconut chips.
- As in the previous method, infuse flax seeds overnight. In the morning add honey, half a glass of yogurt, 100-150 g of fresh strawberries.
- During the night, infuse 2 teaspoons of grains in cold water (100 ml). In the morning add 1 teaspoon of honey, almonds (about 20 grains), sliced orange or grapefruit.
Author: Di & Di Corporation
What are the health benefits of flaxseed and how to use them correctly?
One of the natural ingredients that contribute to the proper functioning of a healthy heart are flax seeds. They can be eaten whole (not chopped) or can be fried or made into flax (linseed crackers). Thus, prevention is carried out to maintain the health of the whole organism.
Attention! Flax seeds help fight the development of cancer cells in the mammary glands, prevent the development of prostatitis, and also reduce the likelihood of cardiovascular disease.
What are the benefits of flax seeds?
A useful base in flax seeds are their fibrous components and oil, which is extracted by cold pressing. This product contains polyunsaturated fatty acids (PUFAs): linoleic acid, which is an omega-6 acid, and alpha-linolenic acid (omega-3 acid). The useful eicosapentaenoic acid (EPA, EPA) and docosahexaenoic acid (DHA, DHA) are synthesized from alpha-linolenic acid in the body. The efficiency of this process is low: for example, in men only 5-8% are converted into EPA, in women – up to 21%. In addition to PUFA, flax seeds contain up to 20-25% protein, up to 12-28% fiber (dietary fiber), as well as mucus polysaccharides, which has an enveloping effect on the walls of the stomach and intestines.
Fibrous components, lignans, interact with estrogen receptors, therefore they are also called phytoestrogens, and flax itself is considered a plant that is beneficial for women’s health.Phytoestrogens can inhibit the formation of cancer cells in the mammary glands and prostate. Seeds are also beneficial for normalizing blood pressure, lowering bad cholesterol, and preventing atherosclerotic plaque formation.
Natural flaxseed oil and ultra-pure complex from marine fish oil MEG-3 are contained in the product Siberian flax and omega-3 – Essential Fatty Acids, the main task of which is to replenish the deficiency of polyunsaturated fatty acids in the body.It helps to improve the state of blood vessels, normalize hormonal levels.
Attention! The main benefit of flax lies in its ability to lower high blood cholesterol levels.
Flaxseeds are also rich in B vitamins, magnesium, potassium and phosphorus. Flaxseed infusions help to normalize metabolism and the functioning of the gastrointestinal tract.
It is also rich in vitamins, amino acids and healthy fats Nutritious cocktail Hazelnuts and green buckwheat from the YooGo operative food series.Each serving is a healthy snack packed with fiber, omega-3 PUFAs, protein, and L-carnitine. The balanced composition provides the body with vital nutrients and helps to keep you feeling full for a long time.
How to use flax seeds?
Experts advise consuming healthy flaxseeds as a simple dietary supplement. If you buy flax seeds yourself, then you should pay attention to the packaging. The container must be in the form of a vacuum package, and the product itself must be sold chilled. This prevents the seeds from deteriorating or oxidizing when exposed to air or sunlight.
It is advised to store them in a closed container, in a cool and dark place. You can use flaxseed once a day as desired, improving your homemade recipes.
Main methods of consumption:
- sprinkle with cold and hot homemade cereals;
- Season boiled or baked vegetables;
- add to lean dishes;
- use when kneading dough;
- fry;
- Prepare flaxes: soak in water for 15-20 minutes to release gluten, and then bake in the oven at 180⁰C for 40-50 minutes, turn over and bake for another 10-15 minutes.
The seeds resemble chopped nuts, giving the dishes a sophisticated and rich flavor.
By the way, if you love nuts and want to have a healthy snack, then for you – Fitness Kozinak Pumpkin-Mango – Yoo Go. It contains natural plant ingredients: vegetables, nuts and fruits. No flavors or colors, just the right calories and a lasting boost of energy!
Attention! The first changes after using them can be noticed within a few weeks.Hair, skin and nails become stronger, stronger and more beautiful. Allergic rashes on the body also disappear.
What is the danger of flax seeds?
Flax seeds contain the glycoside linamarin and the enzyme β-glucosidase, which can interact to form poisonous hydrocyanic acid. In whole flax seeds, their content is small, but when chewing or grinding the seeds, these components react more actively and form hydrocyanic acid in a much larger amount.Therefore, it is not recommended to consume crushed flax seeds.
The process of formation of hydrocyanic acid is enhanced after storage of seeds under the influence of sunlight, so the seeds should be stored in a dark place. For adults, a dose of 10-100 g of crushed seeds is dangerous, for children the dose is even less. Hydrocyanic acid breaks down at temperatures above 170⁰C, so it is best to subject flax seeds to high-temperature processing.
Contraindications
Excessive consumption of flaxseeds can be harmful to health, just like any potent remedy. Elevated levels of fatty acids can cause diarrhea or inflammation in the digestive system.
Seeds should not be consumed by pregnant and lactating mothers, patients with exacerbations of liver and gastrointestinal tract diseases. It is better to consult a doctor before using them.
90,000 benefits and harms (composition, benefits for men, for women, for children)
Everyone knows about the benefits of a plant like flax. It is used to create fabrics, ropes and other industrial elements, as well as unique linseed oil.But no less useful are the seeds of this plant, which have a number of valuable qualities. They are used in pharmaceuticals, medicine, folk methods of treating various diseases by germination. To understand why the plant is so widely used, it would be necessary to find out – what is included in flax, what are the benefits and harms for men, women, pregnant women and children, and whether there are contraindications when taking the remedy.
A bit of history
A beautiful plant with celestial flowers was grown in India, about 9 thousand years ago, and in ancient Babylon it was widely used in the third millennium BC.Then history is silent about the remedy for many diseases. And only by the eighth century, the king of the Frankish state Charlemagne, having heard from his doctor about the unique properties of the plant, issued a decree according to which citizens were obliged to collect the seeds of this plant and use it. Common grains are used, as well as fried brown ones. Oil was squeezed out of it, decoctions were made from cake, leaves, seeds were also ground, which became one of the ingredients of bread. And in ancient Russia there was a special rite – for a new milestone in life – birth, marriage, baptism and other moments had to be met in a new linen long shirt.
In Dagestan, a delicious white dessert, Urbech, is made from flaxseed flour. It resembles in consistency hard molasses, pasta, and the taste is fried nuts mixed with sweets.
Since then, a lot of time has passed, but scientists, nutritionists, general practitioners, gastroenterologists, etc. continue to assert the health of the product under study. Modern medicine fully confirms the correctness of the great Charles and prescribes flax seeds, both in normal and conditions and diseases.
What’s in
We hear a lot about the fact that the diet of people should contain seafood, in particular red fish, starfish, etc. It is clear that not everyone can afford such a menu. Why spend more if the same beneficial substances are available in flax seeds available for any budget level. Let’s say more, the uniqueness of the composition of the product is simply amazing.
- fatty acids: Omega-3, Omega-6, Omega-9 and others;
- soluble fiber;
- easily digestible carbohydrates – glucose, sugar;
- vitamins: the whole group B, PP, C, K, E;
- zeaxanthin; betaine; lutein;
- microelements: sulfur, zinc, iron, magnesium, copper;
- macroelements: manganese, potassium, calcium, fluorine, sodium;
- tryptophan, valine, lysine, phenylalalline, arginine;
- tyrosine, proline, glycine, alanine;
- linoleic, oleic, arachidic and other acids.
90,073 lignins;
Useful properties
The main components of seeds are Omega-3, 6, and 9, which are useful types of fats. Thanks to their presence in the body, good work of the cardiovascular system, memory, prevention of diseases such as heart attack, stroke, atherosclerosis, etc.
Lignins – plant types of compounds capable of performing the properties of antioxidants, estrogens, inhibit the aging process of the body. Regular use will prevent the development of age-related changes, smooth the skin, eliminate wrinkles, fight infections and inflammations, and are also excellent helpers in the fight against free radicals – the harbingers of oncology.
An interesting fact: lignins are found in many foods, but flax seeds contain 500 times more of them.
- Fiber stimulates the process of digestion and the passage of food through the intestines, eliminates stagnant processes, softens fecal stones and removes toxins and toxins from the body. For this reason, the seeds are used to burn fat, normalize metabolism and lose weight.
- Lignins have antiviral, bactericidal and anti-inflammatory properties, and also increase the reproductive capacity of both the female and male body.
- Phosphorus strengthens the enamel of teeth, nails, hair, bone structure, and this mineral also has a beneficial effect on the muscles of the human heart.
- Manganese and selenium regulate water balance.
- Sodium removes excess salt and regulates its level in the body. To do this, the seeds must be insisted in warm boiled water, stir thoroughly for 15 minutes and drink.
- Fatty acids stimulate the quality of the endocrine system, kidneys, liver, thyroid gland, and urinary bladder.
- Magnesium improves cardiac activity, has a calming effect on the nervous system, a person, and his psyche. Flax seeds are an excellent prevention of strokes, heart attacks, vascular diseases. Magnesium also regulates blood sugar levels.
- Flax seeds should be in the first place in the elderly to eliminate inflammation and pain in joints, cartilage tissue.
- Copper is an essential element for the normal functioning of the brain and central nervous system.By stimulating the synthesis of carbohydrates, there is an improvement in brain activity, cognitive functions of a person. And in combination with iron, it improves the quality of blood, increases the level of hemoglobin.
For many, flax has become the best panacea for extra pounds and obesity. In a mixture with cereals, smoothies, fermented milk cocktails, sprouted or ground seeds remove excess liquid, salts, stimulate metabolism, thereby burning excess fats and reducing weight.
Benefit for men
The stronger sex, as a rule, is more often employed in difficult industries.On the shoulders of men, all strength work that requires strength of muscles and bone structure. Flax seeds should be consumed after exhausting and hard training, a hard day. For this reason, cocktails with seeds are included in the diet of athletes.
Chronic inflammatory diseases lead to atherosclerosis, which is the cause of strokes and heart attacks. And men are more often ill with these ailments, for whom it is important to use seeds in the form of flour, as a medicinal infusion, sprouted grains as an additional component in cereals.
Fiber has a mild laxative effect and reduces the risk of colon cancer, which is 1.5 times more common in men than in women. In whole seeds, there is a special synthesis of genes that lead to the death of cancer cells.
With oncological diseases of the prostate gland, men need to lead a healthy lifestyle and eat right. The main item on the menu should be seeds that can stop the development of malignant processes.
Benefit for women
For the fairer sex, the value of seeds from a simple plant must be learned by heart.The colossal amount of acids, vitamins and minerals will allow you to overcome a number of negative conditions and diseases.
- Regular use of the medicinal infusion envelops the walls of the intestinal tract with a healing mucous membrane, protecting it from harmful substances, and creating a beneficial microflora.
- Antioxidants, of which there is a colossal amount in flax, inhibit the aging process and preserve the beauty of a woman.
- Useful substances are saved during critical days – the intensity of pain in the lower abdomen decreases, headache, dizziness, irritability, nervousness are eliminated.The reason for this is lagnans – natural hormones that regulate hormonal metabolism.
- Seeds are also irreplaceable in the diet of a pregnant woman. The same groundless tearfulness, anger, mood swings are frequent companions of the expectant mother during pregnancy. Also, therapeutic flaxseed fiber prevents the accumulation of body fat and helps to maintain weight.
Vitamin F – a unique substance rarely found in nature, controls human appetite and creates a feeling of “fullness”.
Flaxseed – Benefits for Children
The medicinal plant we study and its derivatives are often used to treat childhood diseases and conditions.
Flax kissel recommended:
- for constipation;
- in the presence of ulcerative processes, wounds and burns on the skin;
- for diabetes mellitus;
- for removing worms;
- for the treatment of infectious processes in the respiratory tract.
Doctors do not recommend getting too carried away with the introduction of flaxseeds into the diet for children under 12 years old.In any case, it is important to consult a doctor and study a number of contraindications for use.
Harm and contraindications when taking
Even such a unique remedy as decoctions, flaxseed cereals, sprouted grains should be used taking into account contraindications and harm that can be caused to health.
- It is strictly forbidden to use flax seeds in case of intestinal obstruction and inflammation.
- Do not use the remedy for diarrhea, Crohn’s disease.
- An allergic reaction to flax should be the reason for refusing plant treatment.
There is an opinion that the seeds should not be used during pregnancy, since the use can lead to premature birth, miscarriage.
It is not recommended to take semen in the presence of kidney stones, gall bladder, acute phases of inflammatory processes.
Care should be taken with the seeds studied by us in case of bronchial asthma, problems with the thyroid gland, convulsions, frequent bleeding.
In order not to become a victim of such a unique plant and its derivatives, to get the maximum benefit for the body, you need to consult a doctor and get advice. Taking into account the advice of a specialist and proper intake of healing seeds, you can not only prevent, but also stop the course of any ailment, completely restore health and preserve youth. To do this, you need to prepare delicious jelly, pasta or drink a little decoction of a unique plant.
90,000 Flax Seeds for Women – Tasteful
Are you sure you know everything about the benefits of seeds? They help to get rid of excess weight , normalize the digestive tract, but besides this, they have a very interesting property for women.We’ll talk about this below.
The sensitive topic of small breasts worries many women. Although each representative of the fair sex has charm and charisma, independent of external data, sometimes forms of small size give rise to complexes and self-doubt.
This is where it is worth remembering about the small wonderful seeds that have the ability to influence the splendor of the mammary glands. It’s all about phytoestrogen , which is rich in flax. The female hormone makes the breasts firmer and more elastic.
How to take flax for breast augmentation
Flax seeds can be added in small portions to salads, desserts and cereals. Purposefully flax seeds for breast enlargement are taken in ground form 2 times a day, 1 tablespoon. The powder can be diluted in kefir or yogurt and drink with pleasure.
You can consume a pleasant drink for no more than three months, then you should take a break for a month and repeat the course. Delicious and healthy seeds will help improve metabolism and even lose weight! Agree, a nice bonus to the main effect.
The effect will improve the external use of linseed oil. Take it as a base, add 1-2 drops of ylang-ylang and geranium oil. Every day, massage your breasts with a fragrant mixture: it will make the décolleté area soft and pleasant to the touch, and the breast will be lush .
Contraindications
As with any medicine, flax seeds should be taken with caution. A number of contraindications for use include:
- pregnancy;
- period of exacerbation of colitis, cholecystitis, pancreatitis;
- stones in the gall and bladder.