Flovent Inhalation: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Read the Patient Information Leaflet that comes with this product before you start using fluticasone and each time you get a refill. Read the patient instructions on how to use this inhaler properly. If you have any questions, ask your doctor or pharmacist.

Follow the instructions for priming the inhaler if you are using it for the first time, if you have not used it for more than 1 week, or if you dropped the inhaler. When priming the inhaler, make sure to spray away from your face so that you do not get the medication into your eyes.

Shake the inhaler well for 5 seconds before each use. Inhale this medication by mouth as directed by your doctor, usually twice a day (in the morning and evening). The dosage is based on your medical condition and response to treatment.

Talk to your doctor or pharmacist if you have trouble using this inhaler. Young children may get better results using a spacer device and face mask with this medication.

If two inhalations/puffs are prescribed, wait about 30 seconds between them. Shake the inhaler well between each puff. If you are using other inhalers at the same time, wait at least 1 minute between the use of each medication, and use this drug (the corticosteroid) last.

To prevent dry mouth, hoarseness, and oral yeast infections from developing, gargle, rinse your mouth with water and spit out after each use. Do not swallow the rinse water.

Use this medication regularly to get the most benefit from it. This medication works best if used at evenly spaced intervals. To help you remember, use it at the same times each day. Do not increase your dose, use this medication more often, or stop using it without first consulting your doctor.

If you are regularly taking a different corticosteroid by mouth (such as prednisone), you should not stop taking it unless directed by your doctor. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. If you suddenly stop taking the drug, you may also have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness). To help prevent withdrawal, your doctor may slowly lower the dose of your old medication after you begin using fluticasone. Tell your doctor or pharmacist right away if you have withdrawal. See also Precautions section.

Clean the inhaler regularly as directed. Keep track of the number of inhalations used. Discard the canister after using the labeled number of inhalations on the package, even if it feels as though there is medication left in the canister.

It may take up to 2 weeks or longer before the full benefit of this drug takes effect. Tell your doctor if your condition does not improve or if it worsens.

Learn which of your inhalers you should use every day (controller drugs) and which you should use if your breathing suddenly worsens (quick-relief drugs). Ask your doctor ahead of time what you should do if you have new or worsening cough or shortness of breath, wheezing, increased sputum, worsening peak flow meter readings, waking up at night with trouble breathing, if you use your quick-relief inhaler more often (more than 2 days a week), or if your quick-relief inhaler does not seem to be working well. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away.

Types of Inhalers and Nebulizers

Just when you think you’ve gotten over that respiratory infection, bronchitis hits. The coughing, chest soreness, and fatigue can really get you down.

While acute bronchitis will usually go away without prescription treatments, chronic or an especially nasty case of acute bronchitis may require some extra help.

We explain inhaled treatments for bronchitis, including nebulizer and inhaler treatments, and how they may help.

Inhalers are medications that are delivered through the mouth and to the lungs.

Usually this is a device with a short mouthpiece that connects to a small canister you press down on. When you press down and inhale, the medication enters your mouth and goes down into your lungs.

A doctor may prescribe a few different types of inhaler medications for bronchitis. These include the following:

Beta-2 agonists

Some of the most common inhaler medications are short-acting beta-2 agonists. These include medications like albuterol and salbutamol.

Doctors prescribe beta-2 agonists to treat:

• asthma
• chronic obstructive pulmonary disease (COPD)
• severe coughing that can come with acute bronchitis

These medications work by relaxing airway passages in the lungs, which can make it easier to breathe.

The Cochrane Database of Systematic Reviews analyzed the results of five different studies of beta-2 agonists as a treatment for acute bronchitis in adults.

They concluded that there’s little evidence to support the use of beta-2 agonists in adults with acute bronchitis.

However, they did find that inhalers helped people who tended to wheeze frequently, even when they weren’t sick.

Inhaled corticosteroids

Inhaled corticosteroids help to reduce airway inflammation. This can be helpful when you have bronchitis, because it’s usually after an upper respiratory infection and your lungs are already very irritated.

These medications won’t relieve a wheezing attack immediately, but they can help to reduce:

• airway swelling
• excess mucus
• tight airways

Examples of inhaled corticosteroids doctors prescribe include:

• beclomethasone
• budesonide
• fluticasone

Long-acting beta-2 agonists (LABAs)

These medications are similar to short-acting beta-2 agonists like albuterol. They aren’t meant for acute attacks of wheezing, but rather reduce the risk of wheezing all day.

Examples of LABAs include arformoterol tartrate (Brovana) and formoterol fumarate (Oxeze, Foradil).

Doctors usually prescribe these with inhaled corticosteroids.

Nebulizer treatments are another form of inhaled medications. Instead of a short mouthpiece, nebulizer treatments usually have a longer mouthpiece and an air compressor that helps convert the medication to a fine mist.

Doctors often prescribe nebulizers to children who may have a harder time using an inhaler properly.

Instead of having to time the pumps to breathe medication in, a person just takes deep breaths in and out to take in the medication.

Nebulizers are also useful for people who may require larger amounts of inhaled medications, such as those for:

• acute asthma attacks
• pneumonia
• COPD

A doctor would usually prescribe nebulized medications to treat acute bronchitis in children or for chronic bronchitis in adults.

Examples of nebulized medications include:

• Long-acting beta-2 agonists (LABAs). These medications are usually the same as those available for inhalers.
• Long-acting muscarinic agents (LAMAs). These medications work on different receptors in the lungs than beta-agonists to help open up the airways so you can breathe better. Examples of these medicines include umeclinium (Ellipta) and tiotropium (HandiHaler, Respimat).
• Short-acting beta-agonists (SABAs). Like with traditional inhalers, a person can use albuterol in a nebulizer. These are mostly for acute attacks in bronchitis, such as wheezing.
• Short-acting muscarinic antagonists (SAMAs). These are medications like ipratropium bromide (Atrovent). Doctors prescribe them to treat chronic bronchitis and COPD.

Many of these medications are available in combination, such as SABA-SAMA or LABA-LAMA.

Nebulized medications may not be as good a fit for adults without COPD, because nebulizers require special equipment and teaching to use.

Ideally, a person with acute bronchitis wouldn’t need this type of equipment.

In addition to nebulizers and inhalers, some people may inhale warm, humidified air (steam) at home to improve their breathing.

Sometimes cold air can irritate the lungs and worsen coughing when you have bronchitis. Warm, moist air may help you feel better and reduce coughing.

Here are some ways you can incorporate steam or mist therapy into your bronchitis treatments:

• inhale steam from a bowl of boiling water, while hovering at least 8 to 12 inches away with a towel over your head to hold the steam in
• take a hot shower
• use a humidifier in your room, but be sure to carefully clean it after use

Many drugstores also sell plugin steam inhalers.

The side effects from inhalers and nebulizer treatments depend upon the type used. Examples of side effects include the following:

• Beta-2 agonists may cause tremors, nervousness, and shakiness.
• Corticosteroids can causesore mouth, cough, hoarse voice, or nosebleeds. Oral thrush can develop if a person doesn’t rinse their mouth out after use.
• LABAs can cause heart palpitations and tremors.
• LAMAs may cause constipation, dry mouth, and urinary retention.

If you experience any of these when you use an inhaler or nebulizer, talk to your doctor about ways to minimize these side effects. You can also find out if other medications are available.

They may suggest using a spacer device, which maximizes the delivery of the medication to the lungs. This minimizes the settling of medication to the back of the throat, which can lead to side effects.

With treatment and rest, you’ll ideally recover within about 1 to 2 weeks. It may take a bit longer for some people.

If your symptoms, especially your cough, persist beyond 3 weeks, consider scheduling another appointment with your doctor.

A doctor can evaluate you for other potential coughing causes, such as:

• asthma
• sinusitis
• COPD
• gastroesophageal reflux disease (GERD)
• heart failure
• pulmonary embolism

According to StatPearls, doctors may misdiagnose as many as one-third of patients with bronchitis when the patients actually have asthma.

You should talk with a doctor if you have a cough that persists after an upper respiratory infection, and it keeps you from completing everyday activities or starts to make your chest hurt.

If you have a fever that accompanies your symptoms, your infection may be bacterial. A doctor can prescribe antibiotics that can help bronchitis go away.

If your cough persists after 3 weeks, you may need to make another appointment with your doctor. Bronchitis will usually subside by this time, so you could have another medical condition.

Sometimes, bronchitis can lead to pneumonia. This is a severe lung infection.

Seek emergency medical treatment if you have worsening symptoms like:

• shortness of breath
• blue-tinted lips or fingernails
• confusion

Doctors usually treat bronchitis by treating its symptoms.

If your symptoms include wheezing and coughing, your doctor may prescribe an inhaler or nebulizer. These may help you manage your symptoms until you start feeling better.

PULMONOLOGY. CHRONIC OBSTRUCTIVE LUNG DISEASES: INHALATIONS OF FLUTICASONE PROPIONATE | Kronina L.

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PULMONOLOGY. CHRONIC OBSTRUCTIVE PULMONARY DISEASES: INHALATION OF FLUTICASONE PROPIONATE

PULMONOLOGY. CHRONIC OBSTRUCTIVE LUNG DISEASE: FLUTICASONE PROPIONATE INHALATION

November 03, 1998

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• Cronin L.

For citation: Kronina L. PULMONOLOGY. CHRONIC OBSTRUCTIVE LUNG DISEASES: FLUTICASONE PROPIONATE INHALATIONS. breast cancer. 1998;21:5.

Efficacy of inhaled fluticasone propionate (FP) was evaluated in patients with chronic obstructive pulmonary disease (COPD). A multicenter, randomized, double-blind, placebo-controlled study was conducted in 13 European countries, New Zealand, and South Africa. The study included 281 patients (smokers or those who quit smoking) aged 50 to 75 years with forced expiratory volume in 1 s (FEV1) from 35 to 70% of the predicted value and forced vital capacity of less than 70%. The high efficiency of AF was established with a low frequency of adverse reactions and no effect on the level of endogenous cortisol.

It is known that COPD is a heterogeneous group of diseases (chronic bronchitis, emphysema) with a steady progression of airway obstruction, which is often combined with bronchial hyperreactivity. Clinically, COPD is characterized by productive cough and shortness of breath. Due to the deterioration of lung function in patients, there is a deterioration in the general condition and quality of life, respiratory failure develops, up to death. COPD occupies one of the first places in the structure of mortality.
It has been established that the main risk factor for COPD is smoking, but the pathogenesis of COPD is still not clear. As with asthma, the airways are involved in the inflammatory process. Systemic corticosteroids (systemic CS) cause a large number of adverse reactions. Long-term therapy with inhaled CS improves clinical and functional parameters in patients with asthma, but has been little studied in patients with COPD.
The criteria for excluding patients from the study were the increase in FEV ₁ after inhalation of salbutamol by more than 15%, taking systemic CS, antibiotic therapy.
FP was prescribed 2 puffs (250 µg each) twice a day (1000 µg/day). Patients were examined after 4, 8, 16 and 24 weeks from the start of treatment. An exercise tolerance test was performed (walking along the corridor for 6 minutes, followed by an assessment of dyspnea on the Borg scale from 0 to 10). In all patients, indicators of respiratory function (RF) were determined, clinical and laboratory data were evaluated, the need for b ₂ – agonists, the number and severity of exacerbations were taken into account.
37% of patients in the placebo group and 32% in the AF group had a minimal number of exacerbations at the end of the study. The total number of COPD exacerbations was less after AF treatment. The severity of exacerbations was higher in the placebo group. The mean peak expiratory flow rate (PEF) was 2 L/min in the placebo group and 15 L/min in the AF group. There was an increase in FEV1 by 9.4% after AF treatment, in 29% of patients this figure increased by more than 10%. No dependence of changes in respiratory function on age, sex, smoking, endogenous cortisol level, and baseline parameters of respiratory function was found. The scoring of clinical signs showed high efficacy in the treatment of AF. Exercise tolerance in patients treated with AF was significantly higher than in the placebo group.
The most common adverse reactions were lower respiratory tract infections and dry cough (respectively 13% and 8% in the placebo group, 10% and 10% in the AF group). Dysphonia and candidiasis of the oral cavity occurred much less frequently (respectively 4 and 3% in patients after AF, 1 and 1% in the placebo group). A decrease in the level of endogenous cortisol was detected in 14% of cases in patients who received AF, and in 11% in the placebo group.
The discussion states that previous studies have shown a positive effect of CS therapy in patients with COPD only in the presence of eosinophilia. The present study demonstrated the high efficacy and safety of AF at a dose of 1000 μg per day. It is concluded that inhaled CS may play an important role in the treatment of COPD.

Literature:

Paggiaro LP, et al. Multicentre randomized placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. Lancet 1998;351:773-80.

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Bronchitis

Bronchitis is an inflammation of the bronchial mucosa, caused by prolonged irritation by various harmful factors. It is characterized by a progressive course, impaired mucus formation and functions of the bronchial tree.

Bronchitis occurs in acute or chronic form.

Acute bronchitis is an inflammatory disease of the bronchi, mainly of infectious origin. Acute bronchitis goes away fairly quickly. If the correct treatment is chosen, then it is cured in 2-3 weeks. Unpleasant sensations behind the sternum, dry cough, weakness, fever, shortness of breath are the main symptoms of acute bronchitis. Over time, the cough becomes wet, sputum begins to move away. Symptoms usually subside by 3-4 days and, with a favorable course, completely disappear by 7-10 days.

Chronic bronchitis is a constant inflammation of the bronchi, which periodically worsens. There is a cough with sputum. Chronic bronchitis is when the cough lasts for at least 3 months. per year for 2 consecutive years. Symptoms of bronchitis in the chronic course of the disease are weakness, weakness, chest pain, cough with sputum, fever. Symptoms that are observed in patients with bronchitis are possible with ordinary pharyngitis and pneumonia. Therefore, only a doctor can establish an accurate diagnosis, prescribe the correct treatment and ensure proper control over the development of the disease.

The main thing in the treatment of bronchitis is a sparing regimen, it is recommended to drink plenty of water: hot tea with lemon, honey, raspberry jam, infusion of linden flowers, heated alkaline mineral waters. In the first days of the disease, mustard plasters, cups, an alcohol compress on the chest, hot foot baths, rubbing the chest with turpentine ointment give a good effect.

Since acute infectious bronchitis is caused by viruses, antiviral drugs, which can be bought at Zhivika pharmacies (Remantadin, Arbidol, etc. ), are of primary importance in its treatment. However, if the disease is accompanied by high fever and shortness of breath, a course of antibiotic therapy cannot be avoided. In this case, antibiotics of various groups are used: (Sumamed, Augmentin, Suprax, etc.).

In addition to antimicrobial drugs, to increase the body’s resistance to infection, immunomodulators ([Imudon], [Immunal], Lyzobakt) are usually included in the complex treatment of bronchitis.

I would like to pay special attention to the symptomatic treatment of cough accompanying bronchitis. The choice of medicines, first of all, depends on the nature of the cough, as well as on its intensity. In mild cases, with a dry cough (itching), it is very effective to use lozenges or lozenges, which the pharmacists of Zhivika pharmacies ([Travisil], Dr. Mom, Sage “Green Doctor”) will offer with great pleasure.

With a strong painful cough, antitussive drugs are indispensable ([Codelac], Terpinkod, [Sinekod], [Stoptussin], [Libeksin]).