What are the health benefits of goldenseal. How does goldenseal support the immune system and digestive health. What are the potential side effects and interactions of goldenseal. How should goldenseal be used and dosed.

What is Goldenseal and Its Historical Use?

Goldenseal (Hydrastis canadensis) is a perennial herb native to North America that has been used medicinally for centuries. It belongs to the buttercup family and grows naturally in rich, shady woods. Native Americans originally used goldenseal for a variety of health purposes, including treating skin disorders, digestive issues, liver conditions, diarrhea, and eye irritations.

European settlers learned about the medicinal properties of goldenseal from Native American tribes like the Iroquois. The herb gained widespread popularity in the early 1800s thanks to promotion by herbalist Samuel Thompson, who touted it as a cure-all. While its popularity has fluctuated over time, goldenseal remains one of the most widely used herbal supplements today.

What Are the Key Active Compounds in Goldenseal?

The medicinal effects of goldenseal are attributed to several active compounds, with the most important being:

• Berberine – The primary alkaloid responsible for many of goldenseal’s antimicrobial and immune-stimulating effects
• Hydrastine – Another alkaloid with antimicrobial properties
• Canadine – An alkaloid that may have anti-inflammatory effects
• Canadaline – A lesser-known alkaloid still being researched

Of these, berberine is considered the most potent and well-studied compound. It gives goldenseal its characteristic bright yellow color and is responsible for many of its purported health benefits.

How Does Goldenseal Support Immune Function?

Goldenseal has a long history of traditional use for boosting immune function and fighting infections. Modern research has begun to uncover the mechanisms behind these effects:

Activation of Immune Cells

Studies have shown that berberine can stimulate macrophages, a type of white blood cell crucial for immune defense. Macrophages engulf and destroy harmful microorganisms through a process called phagocytosis. By activating these cells, goldenseal may enhance the body’s ability to fight off pathogens.

Antimicrobial Properties

Berberine and other compounds in goldenseal have demonstrated antibacterial, antiviral, and antifungal properties in laboratory studies. These effects may help the body combat various types of infections.

Inhibition of Microbial Adhesion

Research suggests that berberine can interfere with the ability of certain bacteria to adhere to human cells. This may prevent pathogens from gaining a foothold and causing infection.

While these mechanisms are promising, it’s important to note that most studies have been conducted in vitro or in animals. More human clinical trials are needed to fully understand goldenseal’s effects on immune function.

What Are the Digestive Health Benefits of Goldenseal?

Goldenseal has traditionally been used to support digestive health, and its classification as a “bitter herb” may explain some of these effects:

Stimulation of Digestive Secretions

As a bitter, goldenseal may stimulate the production of saliva, stomach acid, and digestive enzymes. This can potentially improve overall digestion and nutrient absorption.

Support for Gut Flora

The antimicrobial properties of goldenseal may help maintain a healthy balance of gut bacteria by inhibiting the growth of harmful microorganisms.

Potential Anti-inflammatory Effects

Some studies suggest that compounds in goldenseal may have anti-inflammatory properties, which could be beneficial for inflammatory digestive conditions.

While these traditional uses are intriguing, it’s important to note that scientific evidence supporting goldenseal’s digestive benefits is limited. More research is needed to confirm these effects and determine optimal dosing.

Can Goldenseal Help with Skin Conditions?

Goldenseal has a history of topical use for various skin conditions. Its potential benefits for skin health include:

Antimicrobial Action

The antibacterial and antifungal properties of goldenseal may help combat skin infections when applied topically.

Wound Healing

Some herbalists believe that goldenseal can promote wound healing and reduce scarring, although scientific evidence for this is limited.

Anti-inflammatory Effects

The potential anti-inflammatory properties of goldenseal may help soothe irritated skin and reduce redness.

Goldenseal is available in creams and ointments for topical use. However, it’s important to consult with a healthcare professional before using goldenseal for skin conditions, as it can be irritating for some individuals.

What Are the Potential Side Effects and Risks of Goldenseal?

While goldenseal is generally considered safe when used as directed, it can cause side effects in some people:

• Irritation of the mouth and throat
• Nausea and digestive discomfort
• Increased nervousness
• Possible uterine contractions (pregnant women should avoid goldenseal)
• Elevated blood pressure in some individuals

It’s worth noting that side effects are relatively rare. However, the yellow-orange color of liquid goldenseal preparations can cause staining.

Drug Interactions

Goldenseal can interact with various medications. According to recommendations published in the American Family Physician journal, it should not be taken in combination with most over-the-counter and prescription drugs. Always consult with a healthcare provider before using goldenseal, especially if you’re taking other medications.

How Should Goldenseal Be Used and Dosed?

Goldenseal is available in several forms, including:

• Capsules
• Powder
• Tincture
• Tea
• Topical creams and ointments

There is no standard recommended dosage for goldenseal, as scientific evidence is lacking to support specific doses. Product manufacturers often provide varying recommendations on their labels.

When using goldenseal, it’s crucial to follow these guidelines:

1. Always start with the lowest recommended dose and increase gradually if needed.
2. Do not exceed the dosage recommended on the product label or by a healthcare professional.
3. Limit use to short periods (typically no more than 3 weeks) unless otherwise directed by a healthcare provider.
4. Take breaks between periods of use to prevent potential side effects or tolerance.

It’s important to purchase goldenseal products from reputable sources. Look for supplements that have been certified by organizations such as Consumer Labs, The U.S. Pharmacopeial Convention, or NSF International to ensure quality and purity.

Can Goldenseal Help Pass a Drug Test?

A persistent myth suggests that goldenseal can mask illegal drugs in urine tests. This misconception likely originated from a novel written by pharmacist and author John Uri Lloyd. However, there is no scientific evidence to support this claim.

In fact, attempting to use goldenseal to pass a drug test may be counterproductive. Some drug testing facilities now screen for the presence of goldenseal itself, as its use may be considered an attempt to tamper with test results.

It’s essential to understand that no herbal supplement, including goldenseal, has been proven effective in altering drug test results. The only reliable way to pass a drug test is to abstain from drug use.

What Does Current Research Say About Goldenseal’s Efficacy?

While goldenseal has a long history of traditional use and contains compounds with promising properties, scientific research on its efficacy for various health conditions is limited. Most studies have been conducted in vitro or in animals, with few well-designed human clinical trials.

Here’s a summary of the current state of research on goldenseal:

Antimicrobial Effects

Laboratory studies have consistently shown that berberine and other compounds in goldenseal have antimicrobial properties. However, more research is needed to determine how these effects translate to real-world use in humans.

Immune Function

While some studies suggest that goldenseal may stimulate immune function, clinical evidence in humans is lacking. More research is needed to confirm these effects and determine optimal dosing.

Digestive Health

Traditional use supports goldenseal’s potential benefits for digestive health, but scientific evidence is limited. Some studies have explored berberine’s effects on gut health, but more research specific to goldenseal is needed.

Skin Conditions

While goldenseal has been used topically for various skin conditions, scientific evidence supporting its efficacy is limited. More clinical studies are needed to evaluate its effectiveness for specific skin issues.

It’s important to note that the lack of strong scientific evidence doesn’t necessarily mean that goldenseal is ineffective. Rather, it highlights the need for more rigorous research to fully understand its potential benefits and optimal use.

How Does Goldenseal Compare to Other Herbal Remedies?

Goldenseal is often compared to other herbs with similar purported benefits. Here’s how it stacks up against some common alternatives:

Echinacea

Both goldenseal and echinacea are popular for immune support. While echinacea has more clinical research backing its immune-boosting effects, goldenseal’s antimicrobial properties may offer additional benefits.

Garlic

Garlic is another herb known for its antimicrobial and immune-supporting properties. It has more extensive research behind it compared to goldenseal, but some people prefer goldenseal due to its lack of odor.

Oregon Grape

Oregon grape contains berberine, like goldenseal, and is sometimes used as a substitute. However, goldenseal contains additional compounds that may contribute to its overall effects.

Turmeric

While both herbs have anti-inflammatory properties, turmeric has been more extensively studied for this effect. Goldenseal’s primary benefits are more focused on its antimicrobial action.

When choosing between herbal remedies, it’s important to consider individual health needs, potential interactions with medications, and the quality of available scientific evidence. Consulting with a healthcare professional or qualified herbalist can help determine the most appropriate option.

How Can Goldenseal Be Incorporated into a Holistic Health Routine?

While goldenseal shouldn’t be relied upon as a cure-all, it can be a valuable component of a holistic approach to health when used appropriately. Here are some ways to incorporate goldenseal into a comprehensive health routine:

Immune Support

Consider using goldenseal during cold and flu season or when you feel you need extra immune support. It can be taken as a supplement or used to make a soothing tea.

Digestive Health

Goldenseal tea or tincture may be used as a digestive bitter before meals to stimulate digestive secretions. However, it should not be used long-term for this purpose.

Oral Health

Goldenseal tincture diluted in water can be used as a mouthwash for oral hygiene and to soothe mouth sores. Always dilute the tincture properly to avoid irritation.

Skin Care

Topical goldenseal preparations may be applied to minor wounds or skin irritations. However, discontinue use if any irritation occurs.

Remember that herbal remedies like goldenseal should complement, not replace, a healthy lifestyle that includes a balanced diet, regular exercise, stress management, and adequate sleep. Always inform your healthcare provider about any herbal supplements you’re taking to ensure they don’t interact with other treatments or medications.

In conclusion, while goldenseal has a rich history of traditional use and contains compounds with promising properties, more research is needed to fully understand its effects and optimal use. As with any herbal remedy, it’s important to approach its use with caution, under the guidance of a qualified healthcare professional, and as part of a comprehensive approach to health and wellness.

Benefits, Side Effects, Dosage, and Interactions

Goldenseal (Hydrastis canadensis) is one of the most popular herbs on the market today. It was traditionally used by Native Americans to treat skin disorders, digestive problems, liver conditions, diarrhea, and eye irritations. Goldenseal became part of early colonial medical care as the European settlers learned of it from the Iroquois and other tribes.

Goldenseal gained widespread popularity in the early 1800s due to its promotion by a herbalist named Samuel Thompson. Thompson believed goldenseal to be a magical cure for many conditions. Demand for this herb dramatically increased, until Thompson’s system of medicine fell out of popularity. Over the years, goldenseal has gone through periods of popularity.

Goldenseal is available in nutritional supplement form. It is also available as a cream or ointment to heal skin wounds. Other names include yellow root, orange root, puccoon, ground raspberry, and wild curcuma.

Goldenseal herbal tincture can be used as a mouthwash or gargle for mouth sores and sore throats. 

Health Benefits of Goldenseal

According to some alternative medicine practitioners, goldenseal is ​a bitter that stimulates the secretion and flow of bile, and can also be used as an expectorant. In alternative medicine, goldenseal is used for infections of the mucous membranes, including the mouth, sinuses, throat, the intestines, stomach, urinary tract, and vagina. Additional purported uses include:

• Minor wound healing
• Bladder infections
• Fungal infections of the skin
• Colds and flu
• Sinus and chest congestion

Goldenseal became the center of a myth that it could mask a positive drug screen. This false idea was part of a novel written by pharmacist and author John Uri Lloyd.

So far, scientific support for the claim that goldenseal can treat infections (or any other condition) is lacking. 

Possible Side Effects

Side effects of goldenseal include irritation of the mouth and throat, nausea, increased nervousness, and digestive problems, however, side effects are rare. The liquid forms of goldenseal are yellow-orange and can stain.

Interactions

According to recommendations published in the journal American Family Physician, goldenseal should not be taken in combination with most over-the-counter and prescription medications.

One of goldenseal’s chief constituents, berberine, has been reported to cause uterine contractions and to increase levels of bilirubin. Use of goldenseal has been associated with higher blood pressure. Those with heart conditions should only use goldenseal under the supervision of a health professional.

 Verywell / Anastasia Tretiak

Dosage and Preparations

Goldenseal is sold in capsules, powder, tincture, and tea. There is no recommended daily allowance for goldenseal. There is not enough scientific evidence to support any standard dose of goldenseal and product manufacturers vary widely in their labeling recommendations.

What to Look For

When selecting a brand of supplements, look for products that have been certified by Consumer Labs, The U.S. Pharmacopeial Convention, or NSF International. 

Other Questions

How much goldenseal do I need to take to pass a drug test?

Despite its reputation as an agent that can mask illegal drugs in urine, there is no evidence that taking goldenseal prior to a drug test can result in a false negative.

Goldenseal Benefits | Natural Health Guide

Goldenseal is a perennial woodland herb that is a member of the buttercup family. As a native plant of North America, it was highly prized by the Native Americans who used it as a multi-purpose medicinal plant.

It was widely used as an immune booster and for all manner of infections. The roots were boiled and made into a healing tea, poultices and tinctures. It is classed as a bitter herb and as such was an important herb for digestive complaints and stomach aches. Other uses included for fevers, skin conditions and ulcers.

Goldenseal Benefits

Immune System

With a long history of traditional use to treat a broad spectrum of infections, it is now known that Goldenseal contains the powerful plant alkaloid berberine.

Berberine has been shown to stimulate the immune system by activating the macrophages that devour harmful micro-organisms. Macrophages are a type of white blood cell within the immune system that engulf and digest cellular debris, foreign substances, microbes and anything else that does not have the type of proteins specific to healthy body cells on its surface, in a process called phagocytosis.

Additionally, berberine is naturally antibacterial, antiviral and antifungal and has been shown to inhibit the ability of bacteria to attach itself to human cells.

Digestive Health

Goldenseal is classed as a “bitter herb”, bitters stimulate the production of enzymes and stomach acid, readying the digestive system for the optimum assimilation of nutrients from food consumed.

As well as stimulating digestive juices, Goldenseal has a balancing effect on the microbiome. The beneficial bacteria play an important part in the digestive process by breaking down food into usable energy. In a healthy gut, the beneficial bacteria far outnumber the pathogens. However, a course of antibiotics, stress and bad diet can cause an imbalance, allowing the “bad bacteria” to run amok.

A beneficial effect of Goldenseal on the microbiome is “selective microbial inhibition”. In other words, the plant alkaloids in this herb (including berberine), inhibit the growth of dangerous pathogens whilst actually enhancing the growth of beneficial bacteria.

With a powerful anti-inflammatory action, Goldenseal can protect and heal the gut and intestinal tract, providing relief from constipation, bloating and cramping.

Heart Health

The active properties in Goldenseal, particularly its star phytonutrient “berberine”, make it highly effective for protecting and supporting the heart. Berberine can help to regulate heart rhythm and provide relief from arrhythmias and heart palpitations.

A clinical study published in 2001 found that berberine has anti-arrhythmic properties and was found to “prolong the duration of ventricular action potential”. Also known as “cardiac action potential”, this is a brief change in voltage across the cell membrane of heart cells. The study concluded that, “the cardiovascular effects of berberine suggest its possible clinical usefulness in the treatment of arrhythmias and/or heart failure.”

It also has vasodilating properties, meaning that it relaxes and opens the blood vessels which supports healthy blood pressure.

Skin Health

With powerful antioxidant and anti-microbial properties, Goldenseal can be used to combat skin problems such as acne, eczema and psoriasis. It has also been found to be effective against herpes, ringworm, blisters and sores.

Goldenseal can be made into a poultice and applied directly to problem areas, or used as an ingredient in salves, ointments and skin creams.

Also great for cleaning and healing wounds, Goldenseal can be used in place of harsher skin disinfectants to gently clean cuts and bruise and speed up healing.

Goldenseal Medicinal Uses, Health Benefits, Dosage, Side Effects

Goldenseal extract and berberine benefits Influenza A patients.

A study entitled “Inhibition of h2N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis)” done in the Department of Microbiology, North Carolina State University, Raleigh NC, United States, that was published in the International Immunopharmacology 2011 Nov states that isoquinoline alkaloid berberine can inhibit the growth of influenza A. These studies revealed strong effectiveness at high concentrations, although upon dilution extracts were somewhat less effective than purified berberine. Taken together, the results suggest that berberine may indeed be useful for the treatment of infections with influenza A.

Goldenseal extracts synergistically enhance the antibacterial activity of berberine

In a study entitled “Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition” as done in the Department of Chemistry/Biochemistry, The University of North Carolina Greensboro, Greensboro, NC USA., published in the Planta Medicinal 2011 May, states that goldenseal (Hydrastis canadensis L.) can combat inflammation and infection. Its antibacterial activity in vitRO has been attributed to its alkaloids, the most abundant of which is berberine. Synergistic antibacterial activity was observed between the aerial extract (FIC 0. 375) and to a lesser extent the root extract (FIC 0.750) and berberine. These studies indicate that the roots of goldenseal contain higher levels of alkaloids than the aerial portions, but the aerial portions synergize with berberine more significantly than the roots. Furthermore, extracts from the aerial portions of goldenseal contain efflux pump inhibitors, while efflux pump inhibitory activity was not observed for the root extract. The three most abundant goldenseal alkaloids, berberine, hydrastine, and canadine, are not responsible for the efflux pump inhibitory activity of the extracts from H. canadensis aerial portions.

Supplementation with goldenseal inhibits human CYP3

Another study entitled “Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo” done in the Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. As published in the Clinical Pharmacology & Therapeutics 2008 Jan; reported the effects of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on human CYP3A activity. In the study were evaluated using midazolam (MDZ) as a phenotypic probe. Sixteen healthy volunteers were randomly assigned to receive either goldenseal or kava kava for 14 days. Comparisons of pre- and post-supplementation MDZ pharmacokinetic parameters revealed significant inhibition of CYP3A by goldenseal (AUC(0-infinity), 107.9+/-43.3 vs 175.3+/-74.8 ng x h/ml; Cl/F/kg, 1.26+/-0.59 vs 0.81+/-0.45 l/h/kg; T(1/2), 2.01+/-0.42 vs 3.15+/-1.12 h; Cmax, 50.6+/-26.9 vs 71.2+/-50.5 ng/ml). MDZ disposition was not affected by kava kava supplementation. These findings suggest that significant herb-drug interactions may result from the concomitant ingestion of goldenseal and CYP3A substrates.

Goldenseal extract acts as an LDL lowering agent.

In the study “The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms” published in the Journal of Lipid Research, Oct 2006, It is reported that identified berberine (BBR), an alkaloid isolated from the Chinese herb huanglian, has a unique cholesterol-lowering drug that upregulates hepatic low density lipoprotein receptor (LDLR) expression through a mechanism of mRNA stabilization. In this study, it was demonstrated that the root extract of goldenseal, a BBR-containing medicinal plant, is highly effective in upregulation of liver LDLR expression in HepG2 cells and in reducing plasma cholesterol and low density lipoprotein cholesterol (LDL-c) in hyperlipidemic hamsters, with greater activities than the pure compound BBR. The substantial evidence show that goldenseal contains natural MDR1 antagonist(s) that accentuate the upregulatory effect of BBR on LDLR mRNA expression. These new findings identify goldenseal as a natural LDL-c-lowering agent, and our studies provide a molecular basis for the mechanisms of action.

Antimicrobial activity of goldenseal constituents.

In another study entitled “Antimicrobial constituents from goldenseal (the Rhizomes of Hydrastis canadensis) against selected oral pathogens” that was published in the Planta Medicinal Journal of July 2003, reported that two new C-methyl flavonoids, 6,8-di- C-methylluteolin 7-methyl ether (1) and 6- C-methylluteolin 7-methyl ether (2), were isolated from a commercially available sample of the roots of Hydrastis Canadensis (goldenseal), along with seven known compounds, berberine (3), beta-hydrastine (4), canadine (5), canadaline (6), isocorypalmine (7), canadinic acid (8), and beta-sitosterol 3- O-beta- D-glucoside (9). The structures of the new compounds 1 and 2 were elucidated on the basis of their spectral data including 1D and 2D NMR techniques. Of these isolates, berberine (3) and, to a lesser extent, 1 and 2, showed antimicrobial activity when evaluated against the oral pathogens Streptococcus mutans and Fusobacterium nucleatum. Berberine (3) exhibited an additive antimicrobial effect when tested against S. mutans in combination with 1.

Goldenseal Uses, Benefits & Dosage

Scientific Name(s): Hydrastis canadensis L.
Common Name(s): Eyebalm, Eyeroot, Goldenroot, Goldenseal, Ground raspberry, Indian turmeric, Jaundice root, Orangeroot, Radix Hydrastis, Sceau d’or, Yellow puccoon, Yellowroot
Drug class: Herbal products

Medically reviewed by Drugs.com. Last updated on Dec 25, 2020.

Clinical Overview

Use

Traditional uses of goldenseal are not validated by clinical studies, although it may be of use in diabetes, dyslipidemia, cardiovascular conditions, and cancer.

Dosing

Clinical evidence is lacking; few well-controlled clinical trials are available to guide dosage for goldenseal root extract.

Recommended dosages vary considerably, from 250 mg to 1 g 3 times daily. Some product labeling suggests higher dosages.

Traditional dosages include 0.5 to 1 g dried rhizomes 3 times daily, and 0.3 to 1 mL 1:1 liquid extract in 60% ethanol 3 times daily.

Contraindications

None well defined.

Pregnancy/Lactation

Avoid use; activity as a uterine stimulant has been documented. Safety in lactation has not been established.

Interactions

Goldenseal may affect the cytochrome CYP-450 (CYP450) system. The clinical importance of this interaction has not been established.

Adverse Reactions

Information from clinical studies is lacking, but adverse reactions with common doses are rare. Very high doses of goldenseal may occasionally induce nausea, anxiety, depression, seizures, or paralysis.

Toxicology

Toxicological concerns have been reported, with some evidence of carcinogenicity in rodents.

Scientific Family

• Ranunculaceae (buttercup)

Botany

Goldenseal is a perennial herb found in the rich woods of the Ohio River Valley and other locations in the northeastern United States. The single, green-white flower, which has no petals, appears in the spring on a hairy stem above a basal leaf and two palmate, wrinkled leaves. The flower develops into a red-seeded berry. The plant grows from horizontal, bright yellow rhizomes, which have a twisted, knotty appearance.1, 2

History

Native Americans of the Cherokee, Catawba, Iroquois, and Kickapoo tribes used goldenseal root as an insect repellent, diuretic, stimulant, and wash for sore or inflamed eyes. It was used to treat arrow wounds and ulcers, as well as to produce yellow dye. Early settlers learned of these uses from Native Americans, and the root found its way into most 19th century pharmacopeias. The Eclectic medical movement was particularly enthusiastic in its adoption of goldenseal to treat gonorrhea and urinary tract infections. The widespread harvesting of goldenseal in the 19th century, coupled with loss of habitat, resulted in the depletion of wild populations. In 1997, goldenseal was listed under Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora treaty, which controls exports of the root to other countries. The final listing included roots or live plants, but excluded finished products. As an alternative to wild harvesting, goldenseal is cultivated in the Skagit Valley of Washington state and is being promoted as a cash crop in New York, North Carolina, and Canada. The popular notion that goldenseal can be used to affect the outcome of urinalysis for illicit drugs evolved from the novel Stringtown on the Pike by pharmacist John Uri Lloyd. In the book, goldenseal bitters are mistaken for strychnine in a simple alkaloid test by an expert witness in a murder trial. 3, 4, 5, 6, 7 Testing in a small group of healthy volunteers suggests that less sensitive drug assays (threshold higher than 100 ng/mL for morphine) may yield false negative results.

Chemistry

The isoquinoline alkaloids hydrastine (4%), berberine (up to 6%), canadine, and palmatine are present in goldenseal root and are viewed as its principle bioactive components.6, 8 Considerable variation in alkaloid content has been noted among various commercial products, with some not meeting United States Pharmacopeial standards for berberine and hydrastine.6, 9, 10 Some preparations contain alkaloids associated with other herbal substances.9, 11 Other minor alkaloids, such as canadaline and canadinic acid,12, 13 have been isolated. Quinic acid esters were elucidated.14 Traces of calcium, magnesium, potassium, and zinc have been described.15 Quantitation of the alkaloids has been accomplished in a variety of ways, including spectrophotometry, thin-layer chromatography, ion-pair dye colorimetry, high-performance liquid chromatography, capillary electrophoresis, and capillary electrophoresis-mass spectrometry. 2, 7, 10, 11, 16, 17

Uses and Pharmacology

Despite the widespread use of goldenseal, controlled clinical trials are lacking and studies tend to focus on the constituent berberine. The alkaloids are poorly absorbed when taken orally; in vitro and animal studies must be interpreted carefully.17

Antimicrobial activity

Animal data

Goldenseal alkaloids showed modest antimicrobial activity in vitro against Staphylococcus aureus, Klebsiella and Candida species, and Mycobacterium tuberculosis in older studies.18, 19, 20 More recent studies have focused on activity versus Helicobacter pylori,21 methicillin-resistant S. aureus,22 and influenza A virus.23

Clinical data

Older, limited clinical studies evaluated berberine in treating diarrhea due to E. coli and cholera,24, 25 and for use against microbes such as Giardia and Trichomonas.2 Goldenseal has traditionally been used for eye ailments.26 Berberine has been evaluated against sulfacetamide in ocular trachoma infections with comparable effects; however, a phototoxic reaction between berberine alkaloid and ultraviolet A (UVA) light leading to decreased lens epithelial cell viability has been described. 26, 27

Cancer

Animal data

Induction of apoptosis and cell cycle arrest, inhibition of glucose uptake, and tumor promotion have been shown in vitro by both goldenseal and berberine extracts.28, 29, 30, 31 In mice, an ethanolic extract of goldenseal showed some protective activity against induced hepatocarcinoma (lower incidence and slower growth of tumors).32 In a 2-year toxicity study of goldenseal root powder, it was shown to decrease the incidence of mammary gland tumor rates in female rats, possibly because of resulting weight loss.33, 34

Clinical data

Research reveals no clinical data regarding the use of goldenseal in cancer. Berberine alone has been evaluated as an adjunct to prevent adverse effects of radiation.35

Cardiovascular effects

Animal data

Experiments have shown goldenseal and berberine to affect the cardiovascular system, though the mechanisms remain poorly understood. Positive inotropic, negative chronotropic, vasodilatory, and hypotensive effects have been described. 36, 37 In a 2-year toxicity study of goldenseal root powder, the incidence of cardiomyopathy was decreased in male and female rats; however, cardiovascular effects were not the focus of the study.33, 34 Inhibitory activity of goldenseal alkaloids on isolated rabbit aorta stimulated by epinephrine has been evaluated; a weak synergistic effect was found for berberine, canadine, and canadaline, but not for hydrastine.38 Similar studies have been conducted on ileum, trachea, and prostate preparations.39, 40, 41

Clinical data

There is a case report of reversible hypernatremia in a child due to the sodium-sparing diuretic effect of goldenseal.37 In a clinical study (N = 130), patients with acute coronary syndrome following percutaneous coronary intervention who received berberine as adjunctive therapy showed improvements in inflammatory indices.42 Study assessments did not include outcome measures.

Diabetes

Animal data

When administered to mice with induced diabetes, berberine lowered the elevated fasting blood glucose level. Whether this action is via modulation of CYP450 expression or by some other mechanism is unestablished.43

Clinical data

Berberine exerted a hypoglycemic action in a small trial of patients with type 2 diabetes.44 In women with metabolic-associated polycystic ovary syndrome, berberine administered over 3 months decreased fasting blood glucose levels.45 Findings from a larger, multicenter clinical trial evaluating this effect have yet to be published.46

Dyslipidemia

Animal data

Goldenseal decreased low-density lipoprotein in hyperlipidemic rats.47, 48

Clinical data

Berberine alone improved the lipid profile in dyslipidemia in several clinical trials among participants with various conditions, including familial hyperchosterolemia, obesity, and diabetes.44, 49, 50, 51 Clinical trials evaluating goldenseal root powder in dyslipidemia are lacking.

Other uses

Goldenseal administered to rats protected against acetaminophen-induced hepatotoxicity, possibly via modulation of the cytochrome P450 system. 52 In a 2-year toxicity study of goldenseal root powder, it was shown to decrease chronic lung and nasal inflammation.33, 34

Studies evaluating berberine alone have described immunostimulation and antioxidant activity.53, 54, 55 Berberine as a gel has been used orally to treat minor recurrent aphthous stomatitis.56

Although hydrastine is closely related to the convulsant isoquinoline alkaloid bicuculline, it had no activity in a gamma-aminobutyric acid–receptor binding assay at high concentrations.57

Further effects for berberine alone have been described in studies using barberry (see Barberry monograph).

Dosing

Clinical evidence is lacking; few well-controlled clinical trials are available to guide dosage for goldenseal root extract. Recommended dosages vary considerably, from 250 mg to 1 g 3 times daily. Some product labeling suggests higher dosages.47

Berberine alone has been used at 300 to 500 mg 3 times daily in clinical studies.42, 50

Traditional dosages include 0. 5 to 1 g dried rhizomes 3 times daily, and 0.3 to 1 mL 1:1 liquid extract in 60% ethanol 3 times daily.2 Ten to 30 drops of the extract 2 to 4 times a day has been recommended for influenza.58

Pregnancy / Lactation

Avoid use; activity as a uterine stimulant has been documented.2, 59, 60, 61 Safety in lactation has not been established.2 Berberine has been reported to displace bilirubin in rat experiments62 and should not be used in infants with jaundice.

Interactions

Antihypertensives: Herbs (Hypotensive Properties) may enhance the hypotensive effect of Antihypertensives. Monitor therapy.63, 64

ARIPiprazole: CYP3A4 Inhibitors (Weak) may increase the serum concentration of ARIPiprazole. CYP2D6 Inhibitors (Weak) may increase the serum concentration of ARIPiprazole. Monitor therapy.65, 66, 67, 68

Cyclosporine: CYP3A4 inhibitors may increase cyclosporine blood concentrations. Avoid combination.69

Herbs (Hypotensive Properties): May enhance the adverse/toxic effect of other Herbs (Hypotensive Properties). Excessive blood pressure lowering may manifest. Monitor therapy.63, 64

Losartan: CYP2C9 inhibitors may decrease metabolism of losartan to its active metabolite. Avoid combination.70

Lomitapide: CYP3A4 Inhibitors (Weak) may increase the serum concentration of Lomitapide. Consider therapy modification.71

Midazolam: CYP3A4 inhibitors may increase serum concentrations of midazolam. Avoid combination.70, 72

Oseltamivir: In vitro data suggests that oseltamivir’s conversion to the active carboxylate metabolite may be hindered by goldenseal.81

Pimozide: CYP3A4 Inhibitors (Weak) may increase the serum concentration of Pimozide. Avoid combination.73, 74, 75, 76

Adverse Reactions

Information from clinical studies is lacking, but adverse reactions with common doses are rare. Very high doses of goldenseal may rarely induce nausea, anxiety, depression, seizures, or paralysis.2

Caution is warranted in patients with cardiovascular conditions because of the actions of the constituent alkaloids. A large, retrospective evaluation of patient data related to blood pressure and herbal product use found a significantly higher mean systolic blood pressure, but not diastolic blood pressure, in users of goldenseal compared with non-users.80 There is a case report of photosensitivity with the use of a combination product containing ginseng, goldenseal, and bee pollen.77

Toxicology

Findings from a 2-year toxicity study of goldenseal root powder in male and female mice and rats have been published.33, 34 Evidence of carcinogenic activity of the root powder exists, based on an increased incidence of hepatocellular adenoma and carcinoma in both male and female rats, and some evidence in male, but not female, mice after 2 years exposure to goldenseal. An increased incidence of non-neoplastic hepatic lesions has also been demonstrated in rodents.33, 34 DNA damage has been suggested to be due, at least in part, to inhibition of topoisomerases.78

Goldenseal root powder did not show mutagenicity in S. typhimurium or E. coli strains;33, 34 however, berberine showed mutagenicity in yeast cells and the Ames test.2, 61

A phototoxic reaction between berberine alkaloid and UVA light has been described.26, 27

References

1. Hydrastis canadensis L. [Hydrastis canadensis L. goldenseal] USDA, NRCS. 2013. The PLANTS Database (http://plants.usda.gov, 22 November 2013). National Plant Data Team, Greensboro, NC 27401-4901 USA. Accessed February 24, 2014. 2. Rhizoma Hydrastis. In: WHO Monographs On Selected Medicinal Plants. Vol 3. Geneva, Switzerland: World Health Organization; 2001:194-203.3. Hobbs C. Golden seal in early American medical botany. Pharm Hist. 1990;32(2):79-82.116227334. Bolyard J. Medicinal Plants and Home Remedies of Appalachia. Springfield, IL: Charles C. Thomas; 1981.5. Foster S. Goldenseal. Hydrastis canadensis. Botanical Series, No. 309. 2nd ed. Austin, TX: American Botanical Council; 1996.6. Weber HA, Zart MK, Hodges AE, et al. Chemical comparison of goldenseal (Hydrastis canadensis L.) root powder from three commercial suppliers. J Agric Food Chem. 2003;51(25):7352-7358.146405837. Dawes ML, Brettell T. Analysis of goldenseal, Hydrastis canadensis L., and related alkaloids in urine using HPLC with UV detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2012;880(1):114-118.221777878. Inbaraj JJ, Kukielczak BM, Bilski P, He YY, Sik RH, Chignell CF. Photochemistry and photocytotoxicity of alkaloids from goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine. Chem Res Toxicol. 2006;19(6):739-744.167803519. Edwards DJ, Draper EJ. Variations in alkaloid content of herbal products containing goldenseal. J Am Pharm Assoc. 2003;43(3):419-423.1283679410. Govindan M, Govindan G. A convenient method for the determination of the quality of goldenseal. Fitoterapia. 2000;71(3):232-235.1084416011. Van Berkel GJ, Tomkins BA, Kertesz V. Thin-layer chromatography/desorption electrospray ionization mass spectrometry: investigation of goldenseal alkaloids. Anal Chem. 2007;79(7):2778-2789.1733850412. Genest K, Hughes DW. Natural products in Canadian pharmaceuticals. IV. Hydrastis canadensis. Can J Pharm Sci. 1969;4:41-445.13. Galeffi C, Cometa MF, Tomassini L, Nicoletti M. Canadinic acid: an alkaloid from Hydrastis canadensis. Planta Med. 1997;63(2):194.1725234814. Gentry E, Jampani HB, Keshavarz-Shokri A, et al. Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifendine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2. J Nat Prod. 1998;61(10):1187-1193.978414915. Grippo AA, Hamilton B, Hannigan R, Gurley BJ. Metal content of ephedra-containing dietary supplements and select botanicals. Am J Health Syst Pharm. 2006;63(7):635-644.1655428716. Abourashed EA, Khan IA. High-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal. J Pharm Sci. 2001;90(7):817-822.1145833117. Yao M, Ritchie HE, Brown-Woodman PD. A reproductive screening test of goldenseal. Birth Defects Res B Dev Reprod Toxicol. 2005;74(5):399-404.1619349718. Scazzocchio F, Cometa MF, Palmery M. Antimicrobial activity of Hydrastis canadensis extract and its major isolated alkaloids. Fitoterapia. 1998;69(suppl 5):58-59.19. Amin AH, Subbaiah TV, Abbasi KM. Berberine sulfate: antimicrobial activity, bioassay, and mode of action. Can J Microbiol. 1969;15(9):1067-1076.490619120. Sun D, Courtney HS, Beachey EH. Berberine sulfate blocks adherence of Streptococcus pyogenes to epithelial cells, fibronectin, and hexadecane. Antimicrob Agents Chemother. 1988;32(9):1370-1374.305802021. Mahady GB, Pendland SL, Stoia A, Chadwick LR. In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. Phytother Res. 2003;17(3):217-221.1267214922. Cech NB, Junio HA, Ackermann LW, Kavanaugh JS, Horswill AR. Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA). Planta Med. 2012;78(14):1556-1561.2281482123. Cecil CE, Davis JM, Cech NB, Laster SM. Inhibition of h2N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis). Int Immunopharmacol. 2011;11(11):1706-1714.2168380824. Rabbani GH, Butler T, Knight J, Sanyal SC, Alam K. Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae. J Infect Dis. 1987;155(5):979-984.354992325. Khin-Maung U, Myo-Khin, Nyunt-Nyunt-Wai, Aye-Kyaw, Tin-U. Clinical trial of berberine in acute watery diarrhoea. Br Med J (Clin Res Ed). 1985;291(6509):1601-1605. 393520326. Inbaraj JJ, Kukielczak BM, Bilski P, Sandvik SL, Chignell CF. Photochemistry and photocytotoxicity of alkaloids from goldenseal (Hydrastis canadensis L.) 1. Berberine. Chem Res Toxicol. 2001;14(11):1529-1534.1171291127. Chignell CF, Sik RH, Watson MA, Wielgus AR. Photochemistry and photocytotoxicity of alkaloids from goldenseal (Hydrastis canadensis L.) 3: effect on human lens and retinal pigment epithelial cells. Photochem Photobiol. 2007;83(4):938-943.1764566728. Creasey WA. Biochemical effects of berberine. Biochem Pharmacol. 1979;28(7):1081-1084.44426529. Nishino H, Kitagawa K, Fujiki H, Iwashima A. Berberine sulfate inhibits tumor-promoting activity of teleocidin in two-stage carcinogenesis on mouse skin. Oncology. 1986;43(2):131-134.308184430. Kim JB, Yu JH, Ko E, et al. The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest. Phytomedicine. 2010;17(6):436-440.1980077531. Saha SK, Sikdar S, Mukherjee A, Bhadra K, Boujedaini N, Khuda-Bukhsh AR. Ethanolic extract of the Goldenseal, Hydrastis canadensis, has demonstrable chemopreventive effects on HeLa cells in vitro: Drug-DNA interaction with calf thymus DNA as target. Environ Toxicol Pharmacol. 2013;36(1):202-214.2362894932. Karmakar SR, Biswas SJ, Khuda-Bukhsh AR. Anti-carcinogenic potentials of a plant extract (Hydrastis canadensis): I. Evidence from in vivo studies in mice (Mus musculus). Asian Pac J Cancer Prev. 2010;11(2):545-551.2084314933. Dunnick JK, Singh B, Nyska A, Peckham J, Kissling GE, Sanders JM. Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle. Toxicol Pathol. 2011;39(2):398-409.2130079034. National Toxicology Program. Toxicology and carcinogenesis studies of goldenseal root powder (Hydrastis canadensis) in F344/N rats and B6C3F1 mice (feed studies). Natl Toxicol Program Tech Rep Ser. 2010;(562):1-188.2137285835. Li GH, Wang DL, Hu YD, et al. Berberine inhibits acute radiation intestinal syndrome in human with abdomen radiotherapy. Med Oncol. 2010;27(3):919-925.1975721336. Lau CW, Yao XQ, Chen ZY, Ko WH, Huang Y. Cardiovascular actions of berberine. Cardiovasc Drug Rev. 2001;19(3):234-244.1160704137. Bhowmick SK, Hundley OT, Rettig KR. Severe hypernatremia and hyperosmolality exacerbated by an herbal preparation in a patient with diabetic ketoacidosis. Clin Pediatr. 2007;46(9):831-834.1758500838. Palmery M, Cometa MF, Leone MG. Further studies of the adrenolytic activity of the major alkaloids from Hydrastis canadensis L. on isolated rabbit aorta. Phytother Res. 1996;10(suppl 1):S47-S49.39. Cometa MF, Galeffi C, Palmery M. Acute effect of alkaloids from Hydrastis canadensis L. on guinea pig ileum: structure-activity relationships. Phytother Res. 1996;10:S56-S58.40. Baldazzi C, Leone MG, Casini ML, Tita B. Effects of the major alkaloid of Hydrastis canadensis L., berberine, on rabbit prostate strips. Phytother Res. 1998;12(8):589-591.41. Abdel-Haq H, Cometa MF, Palmery M, Leone MG, Silvestrini B, Saso L. Relaxant effects of Hydrastis canadensis L. and its major alkaloids on guinea pig isolated trachea. Pharmacol Toxicol. 2000;87(5):218-222.1112950142. Meng S, Wang LS, Huang ZQ, et al. Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention. Clin Exp Pharmacol Physiol. 2012;39(5):406-411.2222093143. Chatuphonprasert W, Nemoto N, Sakuma T, Jarukamjorn K. Modulations of cytochrome P450 expression in diabetic mice by berberine. Chem Biol Interact. 2012;196(1-2):23-29.2234283244. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008;57(5):712-717.1844263845. Wei W, Zhao H, Wang A, et al. A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome. Eur J Endocrinol. 2012;166(1):99-105.2201989146. Li Y, Ma H, Zhang Y, et al. Effect of berberine on insulin resistance in women with polycystic ovary syndrome: study protocol for a randomized multicenter controlled trial. Trials. 2013;14:226-6215-14-226.2386692447. Abidi P, Chen W, Kraemer FB, Li H, Liu J. The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms. J Lipid Res. 2006;47(10):2134-2147.1688556548. Zhou JY, Zhou SW, Zhang KB, et al. Chronic effects of berberine on blood, liver glucolipid metabolism and liver PPARs expression in diabetic hyperlipidemic rats. Biol Pharm Bull. 2008;31(6):1169-1176.1852005049. Pisciotta L, Bellocchio A, Bertolini S. Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment. Lipids Health Dis. 2012;11:123.2299897850. Hu Y, Ehli EA, Kittelsrud J, et al. Lipid-lowering effect of berberine in human subjects and rats. Phytomedicine. 2012;19(10):861-867.2273941051. Cianci A, Cicero AF, Colacurci N, Matarazzo MG, De Leo V. Activity of isoflavones and berberine on vasomotor symptoms and lipid profile in menopausal women. Gynecol Endocrinol. 2012;28(9):699-702.2231317152. Yamaura K, Shimada M, Nakayama N, Ueno K. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats. Pharmacognosy Res. 2011;3(4):250-255.2222404853. Kim JS, Tanaka H, Shoyama Y. Immunoquantitative analysis for berberine and its related compounds using monoclonal antibodies in herbal medicines. Analyst. 2004;129(1):87-91.1473758954. Misík V, Bezáková L, Máleková L, Kostálová D. Lipoxygenase inhibition and antioxidant properties of protoberberine and aporphine alkaloids isolated from Mahonia aquifolium. Planta Med. 1995;61(4):372-373.748019055. Periera da Silva A, Rocha R, Silva CM, Mira L, Duarte MF, Florêncio MH. Antioxidants in medicinal plant extracts. A research study of the antioxidant capacity of Crataegus, Hamamelis and Hydrastis. Phytother Res. 2000;14(8):612-616.1111399856. Jiang XW, Zhang Y, Zhu YL, et al. Effects of berberine gelatin on recurrent aphthous stomatitis: a randomized, placebo-controlled, double-blind trial in a Chinese cohort. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(2):212-217.2324622957. Kardos J, Blaskó G, Kerekes P, Kovács I, Simonyi M. Inhibition of [3H]GABA binding to rat brain synaptic membranes by bicuculline related alkaloids. Biochem Pharmacol. 1984;33(22):3537-3545.609585258. Chatterjee P, Franklin MR. Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components. Drug Metab Dispos. 2003;31(11):1391-1397.1457077259. Brinker FJ. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications; 1998.60. Ernst E. Herbal medicinal products during pregnancy: are they safe? BJOG. 2002;109(3):227-235.1195017661. Duke JA. Handbook of Medicinal Herbs, Second Edition. CRC Press; 2002.10.1201/9781420040463.Ch462. Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate. 1993;63(4):201-208.851302463. Richard CL, Jurgens TM. Effects of natural health products on blood pressure. Ann Pharmacother. 2005;39(4):712-20.1574142564. Ernst E. Cardiovascular adverse effects of herbal medicines: a systematic review of the recent literature. Can J Cardiol. 2003;19(7):818-27.1281361665. Abilify (aripiprazole) [prescribing information]. Princeton, NJ: Bristol-Myers Squibb; February 2011.66. Kubo M, Koue T, Inaba A, et al. Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic aripiprazole. Drug Metab Pharmacokinet. 2005;20(1):55-64.1577007567. Azuma J, Hasunuma T, Kubo M, et al. The relationship between clinical pharmacokinetics of aripiprazole and CYP2D6 genetic polymorphism: effects of CYP enzyme inhibition by coadministration of paroxetine or fluvoxamine. Eur J Clin Pharmacol. 2012;68(1):29-37.2173926768. Hendset M, Molden E, Enoksen TB, Refsum H, Hermann M. The effect of coadministration of duloxetine on steady-state serum concentration of risperidone and aripiprazole: a study based on therapeutic drug monitoring data. Ther Drug Monit. 2010;32(6):787-790.2106865069. Wu X, Li Q, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol. 2005;61 (8):567-572.1613355470. Guo Y, Chen Y, Tan ZR, Klaassen CD, Zhou HH. Repeated administration of berberine inhibits cytochromes P450 in humans. Eur J Clin Pharmacol. 2012;68 (2):213-217.2187010671. Juxtapid (lomitapide) [prescribing information]. Cambridge, MA: Aegerion Pharmaceuticals, Inc; December 2012.72. Gurley BJ, Swain A, Hartsfield F, et al. Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo. Clin Pharmacol Ther. 2008;83(1):61-69.1749587873. Desta Z, Kerbusch T, Flockhart DA. Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy, poor, and extensive metabolizers of cytochrome P450 2D6 (CYP2D6). Clin Pharmacol Ther. 1999;65(1):10-20.995142674. Orap (pimozide) [prescribing information]. Sellersville, PA: Teva Pharmaceuticals USA; August 2011.75. Flockhart DA, Richard E, Woosely RL, Pearle PL, Drici MD. A metabolic interaction between clarithromycin and pimozide may result in cardiac toxicity. Clin Pharmacol Ther. 1996;59:189.76. Desta Z, Kerbusch T, Soukhova N, et al. Identification and characterization of human cytochrome P450 isoforms interacting with pimozide. J Pharmacol Exp Ther. 1998;285(2):428-437.958058077. Palanisamy A, Haller C, Olson KR. Photosensitivity reaction in a woman using an herbal supplement containing ginseng, goldenseal, and bee pollen. J Toxicol Clin Toxicol. 2003;41(6):865-867.1467779878. Chen S, Wan L, Couch L, et al. Mechanism study of goldenseal-associated DNA damage. Toxicol Lett. 2013;221(1):64-72.2374741479. Gorodetzky CW. Beating the urine test for heroin: ingestion of water and the herb, goldenseal (GS). Federation proceedings. 2012;36(3):4053. http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/247/CN-00198247/frame.html. Accessed June 17, 2014.80. McCarty CA, Berg RL, Rottscheit CM, Dart RA. The use of dietary supplements and their association with blood pressure in a large Midwestern cohort. BMC Complement Altern Med. 2013 Nov 28;13(1):339.2428338181. 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Goldenseal Benefits & Information (Hydrastis Canadensis)

Goldenseal is a perennial herb in the buttercup family Ranunculaceae, and is one of the most popular herbs sold on the American market and has recently gained a reputation as a herbal antibiotic and immune system enhancer.

American Indians used goldenseal as a medication for inflammatory internal conditions such as respiratory, digestive and genito-urinary tract inflammation induced by allergy or infection. The Cherokee used the roots as a wash for local inflammations, a decoction for general debility, dyspepsia, and to improve appetite. The Iroquois used a decoction of the root for whooping cough, diarrhea, liver disease, fever, sour stomach, flatulence, pneumonia, and with whiskey for heart trouble. They also prepared a compound infusion with other roots for use as drops in the treatment of earache and as a wash for sore eyes.

It was not until 1798 that its medicinal virtues began to attract attention. From then on its reputation as a powerful healing herb spread, both in England and America, and by about 1850 it had became an important article of commerce. It was popularly used as a bitter stomach digestive (to help stimulate digestion and improve appetite), to treat skin inflammations, and those of the eyes such as conjunctivitis. It was also used for inflammation of the mucous membranes of the throat and digestive system. It?s traditional uses also include the treatment of peptic ulcers, gastritis, dyspepsia and colitis. It is said to stimulate appetite and generally have a toning effect on the whole body has also been used for anorexia nervosa. It is also said to be effective for treatment of catarrhal conditions of the upper respiratory tract and inflammations of the urinary tract.

Goldenseal has numerous uses that are attributed to its antibiotic, anti-inflammatory and astringent properties. It soothes irritated mucus membranes aiding the eyes, ears, nose and throat. Taken at the first signs of respiratory problems, colds or flu, Goldenseal helps can help to prevent further symptoms from developing. It has also been used to help reduce fevers, and relieve congestion and excess mucous.

Goldenseal cleanses and promotes healthy glandular functions by increasing bile flow and digestive enzymes, therefore regulating healthy liver and spleen functions. It can relieve constipation and may also be used to treat infections of the bladder and intestines as well.

Goldenseal contains calcium, iron, manganese, vitamin A, vitamin C, vitamin E, B-complex, and other nutrients and minerals. The roots and rhizomes of goldenseal contain many isoquinoline alkaloids, including hydrastine, berberine, canadine, canadaline, and l-hydrastine as well as traces of essential oil, fatty oil and resin. It is believed that the high content of these alkaloids gives its antibiotic, anti-infective and immune stimulating qualities.

In particular it is the alkaloid berberine that is most likely responsible for Goldenseal’s effectiveness against bacteria, protozoa, fungi, Streptococci and it also promotes easier removal of the bacteria by inhibiting their ability to adhere to tissue surfaces. Berberine is also anti-fungal and strongly anti-diarrheal. It aids against the infection of mucous membranes such as the lining of the oral cavity, throat, sinus, bronchial, genito-urinary tract and gastrointestinal tract. Clinical studies have shown it is effective in the treatment of diarrhea caused by E. coli (traveller’s diarrhea), Shigella dysenteriae (shigellosis), salmonella paratyphi (food poisoning), giardia lamblia (giardiasis), and vibrio cholerae (cholera).

Goldenseal may also help with allergic rhinitis, hay fever, laryngitis, hepatitis, cystitis, and alcoholic liver disease.

It has proven its value in cases of diarrhea and hemorrhoids. Its astringent properties have also been employed in cases of excessive menstruation and internal bleeding. Externally, a wash can be prepared to treat skin conditions such as eczema and ringworm, as well as wounds and badly healing sores, or used as drops in cases of earache and conjunctivitis. The decoction is also said to be effective as a douche to treat trichomonas and thrush. As a gargle it can be employed in cases of gum infections and sore throats. The application of a paste or poultice containing goldenseal root is sometimes recommended for boils, abscesses and carbuncles on the grounds that Goldenseal helps to kill bacteria and reduce inflammation.

What Are the Benefits of Yellow Root?

Goldenseal is yellow root.

Image Credit: Siri Stafford/Photodisc/Getty Images

Yellow root, most commonly referred to as goldenseal, may have antimicrobial, antibacterial, and antiviral properties. This herb dates back to the Native American tribes who used yellow root as a remedy for digestive disorders such as gastritis, eye infections such as conjunctivitis, gonorrhea, canker sores, urinary tract infections and skin issues. According to the University of Maryland Medical Center, yellow root has become one of the most popular herbs in the United States; however, there is minuscule evidence that supports any of the claims made about this herb.

About Yellow Root

Yellow root, or Hydrastis canadensis, is a small plant with a hairy stem, jagged leaves, small flowers and raspberry-looking fruit. It used to grow all over the United States, but because of the plant being over-harvested, it is now considered an endangered species. Medicinally, the roots and stems of this plant are used. They are bright yellow to yellow-brown in color and have a distinct smell and a bitter taste. Yellow root’s most active ingredient is berberine, which has been thought to treat eye infections and severe cases of diarrhea. The amount of berberine found in this herb is small; scientific studies have yet to prove its effectiveness for certain. Yellow root can be found in tea, liquid extract, tablet and capsule form. It is also often combined with other herbs such as echinacea.

Immune Booster

Yellow root may be an effective immune booster, because it contains two alkaloids known as berberine and canadine that appear to harbor mild immune-stimulating effects. In a study published in the September 2008 issue of the “Journal of Medicinal Food,” researchers found that goldenseal may have the ability to regulate macrophages, or the white blood cells that take in foreign material that often try to compromise the immune system. However, the study showed that this may be caused indirectly by yellow root’s natural ability to reduce the inflammatory response and may not be as effective when used to directly treat the infection. Most research that has been done were test tube studies only. Research needs to be performed on humans to deem this an effective immune booster.

Lowers Cholesterol

Yellow root may also be heart-healthy, helping lower low-density lipoprotein or LDL cholesterol levels. In a study published in the October 2006 issue of the “Journal of Lipid Research,” scientists found that goldenseal extract is effective in reducing overall cholesterol and lowering LDL cholesterol levels in lab animals. During this study, they found that canadine and berberine were both effective up-regulators, or agents that make cells more sensitive to change, on low density lipoprotein receptors causing them to naturally lower cholesterol levels. Although human studies need to be done, these are promising results.

Warnings

Yellow root, in small doses and for short-term use, appears to be safe. Some side effects may include nausea, abdominal discomfort and vomiting. It may also irritate the mouth, throat and skin, as well as cause an increased sensitivity to light. Yellow root should not be taken by women who are breast-feeding or who are pregnant, and it should not be given to newborns or small children because it could cause jaundice or kernicterus. Those who suffer from liver or heart disease or have high blood pressure, are taking anticoagulants or tetracycline should not use yellow root. Any use of an herb, including yellow root, should be done under the supervision and cooperation of a doctor.

17 Herbs for Mind and Body Benefits, Says Science

When the ancients overindulged, they didn’t hit CVS for some antacids. They made a tea of filipendula ulmaria, or meadowsweet, for heartburn relief. And you can, too.

To remedy minor ailments, forego the pharmaceuticals and give natural nutraceuticals a try. Below is our list of 20 herbs that have been proven to work, taken from our book The 7-Day Flat Belly Tea Cleanse.

Stick to the dosages specified here, in the studies, or on the label—and make sure to tell your doctor about any herbs or vitamin supplements you plan to take, especially if you are pregnant or nursing, have a chronic condition, or take medication regularly. Remember that even though herbs are natural, they can still be contraindicated, and supplements are not FDA regulated. For more on strengthening your body’s defenses with supplements, check out 8 Best Immune-Boosting Supplements, According to Doctors.

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BEST FOR: Arthritis and joint injuries

Also known as Indian frankincense, this gummy resin has been clinically proven to have strong anti-inflammatory effects. Boswellia is known to reduce congestion and heat (kapha and pitta elements in Ayurveda) in the joints and is also used to promote appetite and digestion. In a study published in Arthritis Research & Therapy, researchers gave people with osteoarthritis of the knee an extract of boswellia (5-Loxin). After three months, the herb group showed significantly greater relief than a group given a placebo.

DOSAGE: Take one 300-milligram capsule three times a day, with food.

RELATED: Sign up for our newsletter to get daily recipes and food news in your inbox!

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BEST FOR: Arthritis and cancer prevention

Curcumin, the active compound that gives the spice turmeric its bright-gold color, has long been known as an anti-inflammatory and antioxidant. In combination with Boswellia, ashwagandha, and ginger, it may treat osteoarthritis, according to a study published in the Journal of Clinical Rheumatology. And a recent study published in the journal Phytotherapy Research found curcumin to be “comparable” in efficacy to diclofenac sodium, a prescription anti-inflammatory, for treating rheumatoid arthritis.

The American Cancer Society has reported that large studies are being conducted to see how curcumin might prevent and treat cancer; one of the challenges is that it doesn’t absorb well from the intestines, but that could be an advantage for targeting cancer precursors in the colon and rectum. For women with recurrent breast cancer, curcumin might prove especially useful; animal models have shown that curcumin may help prevent metastasis, even after failed treatment with the drug tamoxifen. In women with HER2-positive cancer, curcuminoids also seemed to behave much like the highly successful chemotherapy drug Herceptin, although research is very preliminary.

DOSAGE: It’s best to get your curcumin by using turmeric in curries and other foods. (See: 21 Winning Turmeric Recipes.) If you aren’t a fan of Indian food, take one 500-milligram capsule of curcumin—standardized to 95% curcuminoids—each day.

PRECAUTIONS: Side effects are rare but include flatulence, diarrhea and heartburn. Do not take turmeric if you’re on blood thinners.

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BEST FOR: Common cold

Studies on the effectiveness of echinacea for treating the common cold have been mixed. The largest so far was in 2012 at Cardiff University Common Cold Centre in the U.K., which found that three doses daily, taken for four months reduced the number of colds, and reduced the duration by 26%. The study was peer-reviewed and published in the journal Evidence-Based Complementary and Alternative Medicine. The study was funded by the Swiss manufacturers of Echinaforce. But many experts advise ignoring the naysayers and following traditional usage.
“Native Americans used Echinacea angustifolia—not Echinacea purpurea—and they used only the root,” explains Sheila Kingsbury, N.D., chair of the Department of Botanical Medicine at Bastyr University in Seattle. “Clinically speaking, accessing the root is the best place to start. It can shorten the length of a cold significantly.”

DOSAGE: One teaspoon of echinacea root glycerite liquid every two hours beginning at onset of symptoms; decrease the dose to once every three to four hours after symptoms ease.

For more ways to ease your cold symptoms, don’t miss 17 Magic Foods That Relieve Cold Symptoms.

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BEST FOR: Intestinal gas

Fennel seeds contain phytonutrients that are thought to reduce spasms in small muscle fibers like those found in the intestines, helping to reduce gassiness. The aromatic quality of the seeds will also help freshen your breath. And a 2011 review published in Pediatrics, for instance, found that fennel tea can be useful for treating a baby’s gas-caused colic.

DOSAGE: Chew a pinch of whole fennel seeds after a meal. Your body will let you know—with one last burst of gas—when to stop.

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BEST FOR: Heart health

Nearly twice as many American women die of heart disease and stroke as from all forms of cancer, including breast cancer, according to the American Heart Association (AHA). One reason: high cholesterol. In fact, women tend to have higher cholesterol levels than men from age 45 on, according to the AHA. Flaxseed, which is rich in the omega-3 fat alpha-linolenic acid, may help lower it.

An Italian study of 40 male and female patients with cholesterol levels greater than 240 milligrams per deciliter found that consuming ground flaxseed (20 grams, or about 0.7 ounces, daily) could significantly lower levels of total and LDL cholesterol (the artery-clogging kind), while also improving the ratio of total cholesterol to HDL. (Low levels of HDL may be a greater risk factor for women, according to the AHA.) In a Harvard study of 76,763 women participating in the Nurses’ Health Study, researchers also noted that women consuming a diet rich in alpha-linolenic acid seem to have a lower risk of dying from heart disease and stroke, compared with women whose diets were lacking this fat. Flaxseed is also a high-fiber food; two tablespoons of ground flaxseed have 4 grams of fiber—almost 20% of the 25 grams recommended by the U.S. Department of Agriculture. Lignans, which are a particular type of fiber found in flaxseed, may also be beneficial for preventing breast and prostate cancer, according to preliminary studies. (Lignans are not present in flaxseed oil, however, notes integrative physician and herbalist Tieraona Low Dog, M.D.)

DOSAGE: Low Dog recommends adding 1 to 5 tablespoons of ground flaxseed to your diet several days a week; sprinkle it on cereal or yogurt or stir it into protein shakes. Flaxseed oil—which must be kept refrigerated to prevent rancidity—should be added to salads and not used for cooking.

PRECAUTIONS: Flaxseed and its oil are safe if consumed in normal amounts, although they can produce a laxative effect. “If you eat huge amounts of flaxseed meal, you could develop cyanide toxicity, but this hasn’t, to my knowledge, ever occurred in humans,” says Low Dog.

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BEST FOR: Ear infections and cancer prevention

Garlic’s antibiotic compound, alliin, has no medicinal value until the herb is chewed, chopped or crushed. Then an enzyme transforms alliin into a powerful antibiotic called allicin. Raw garlic has the most antibiotic potency, but garlic still has benefits when cooked. Garlic is antimicrobial and anti-inflammatory, so it will treat any infection, but when combined with mullein oil (Verbascum densiflorum), it’s especially effective for ear infections, says a 2010 report in Archives of Pediatric Adolescent Medicine. The mullein oil is soothing and helps draw out fluid to relieve pain and decrease pressure. According to the National Cancer Institute, preliminary studies in 2008 suggest that garlic consumption may also reduce the risk of developing several types of cancer, especially those of the gastrointestinal tract.

DOSAGE: Put three drops of oil in each affected ear, two to three times a day as needed. (The oils are sold in a premixed formula.) For internal use, fresh garlic or capsules may be used; follow label directions.

PRECAUTIONS: Don’t put drops—or anything else—into your ear if you think the eardrum may be perforated.

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BEST FOR: Nausea and vomiting

A Danish study showed that new sailors prone to motion sickness had less vomiting than a placebo group. Research published in Obstetrics & Gynecology found that 88% of nausea-plagued pregnant women got relief when they took 1 gram a day of ginger powder for no longer than four days.

DOSAGE: For motion sickness, take a 1-gram capsule of powdered ginger root about an hour before you embark and another every two hours or as needed. For morning sickness, take 250 milligrams four times a day. Cooking with the herb may also be helpful.

PRECAUTIONS: Few side effects are linked to normal ginger consumption, but powdered ginger may produce bloating or indigestion. Ginger may also exacerbate heartburn in pregnant women. As could 18 Foods Making Your Heartburn Worse.

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BEST FOR: Liver health

Silymarin in milk thistle seeds has a remarkable ability to protect the liver. This herb has been shown to help treat hepatitis and alcoholic cirrhosis. “In our analysis,” says Mark Blumenthal, executive director of the American Botanical Council, “a clear majority of studies support milk thistle seed extract for liver conditions.” A 2010 NIH-NCCAM study on the effects of silymarin on hepatitis C hepatology showed multiple positive effects demonstrating its antiviral and anti-inflammatory properties. Because most drugs are metabolized through the liver, many herbalists recommend silymarin for anyone who takes liver-taxing medication.

DOSAGE: 500 milligrams daily for liver health; also can be steeped in a tea.

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BEST FOR: Immune enhancement and diabetes

Many studies show that ginseng has “adaptogenic” powers, which means it helps the body adapt to stress and revs up the immune system. Most studies have used Panax ginseng (Asian ginseng). A 2013 University of Maryland review found that Asian ginseng may help boost the immune system, reduce the risk of cancer, and improve mental performance and wellbeing. And subjects who took daily doses of ginseng got fewer colds and less severe symptoms than a placebo group. Ginseng also reduces blood sugar levels. A study in Toronto, Canada, found that Korean red ginseng improved glucose and insulin regulation in well-controlled type 2 diabetes. (Of course, diabetes requires professional treatment, so consult your physician about using ginseng.) Studies also have found ginseng supports liver function and one preliminary study suggests that American ginseng (Panax quinquefolius), in combination with ginkgo (Ginkgo biloba), may help treat ADHD.

DOSAGE: 500 milligrams daily, best for short-term, stressful events

PRECAUTIONS: Should not be taken for more than six weeks. Avoid caffeine when taking ginseng, and do not take if pregnant.

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BEST FOR: Nasal congestion

Goldenrod is particularly effective for treating congestion caused by allergies. Surprised? That’s because goldenrod gets a bad rap. “People blame goldenrod for their allergies because they look across the field and see the beautiful yellow flowers,” says herbalist Margi Flint, author of The Practicing Herbalist. “But it’s the blooming ragweed they can’t see that causes all the trouble. In nature, the remedy often grows right next to the cause.” Also used for urinary infections and cystitis, and to flush out kidney and bladder stones.

DOSAGE: Place three drops of the extract under the tongue; repeat as necessary until nasal passages are clear.

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BEST FOR: Digestive-tract infections

Goldenseal, an herbal antibiotic, is often marketed in combination with echinacea as a treatment for infections, but it is effective only in the digestive tract, not for colds or flu. A 2012 University of Maryland study reported in Clinical Advisor found that goldenseal is an effective antibacterial agent and an aid to digestion. For gastrointestinal infections (e.g., ulcers, food poisoning, infectious diarrhea), ask your doctor about using goldenseal in addition to medical therapies. Also, can be used topically for wounds and infections.

DOSAGE: For internal use, take a 300-milligram capsule three times a day; apply a dilution as needed for external use.

PRECAUTIONS: Can be toxic if taken to excess. May interact with antidepressants and codeine. Do not use if pregnant, nursing or suffering from high blood pressure.

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BEST FOR: Headaches

“The scent of lavender triggers a calming response, releasing tension in the scalp muscles a bit, which eases the pain,” explains Kingsbury Herbalist Rosemary Gladstar. She recommends using lavender oil in a pain-relieving foot soak: Add a few drops to a hot footbath, and then put a cold lavender-infused pack on the forehead. “This draws heat away from the head, and is guaranteed to make you feel better,” she says.

DOSAGE: Dab a few drops of essential oil on each temple and rub some around the hairline. Breathe deeply and relax; repeat as needed.

PRECAUTIONS: Do not take the essential oil internally unless under the care of a professional.

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BEST FOR: Anxiety and herpes

Science has shown that lemon balm is tranquilizing. Several double-blind studies have found that a 600-milligram dose promoted calm and reduced anxiety. The herb and its oil have been used in Alzheimer’s special care units to calm those who are agitated. (Related: 5 Foods To Help Prevent Alzheimer’s, According to Doctors.)

To decompress after a tough day, try a cup of lemon balm tea; for extra benefit, mix with chamomile. Lemon balm also has antiviral properties and has been shown to reduce the healing time of both oral and genital herpes. German researchers gave people in the early stages of herpes simplex virus outbreaks lemon balm cream or a placebo. The herb group had milder outbreaks that healed faster.

DOSAGE: Available in capsule form, tincture, and essential oil; follow label instructions.

PRECAUTIONS: Do not take the essential oil internally unless under the care of a professional.

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BEST FOR: Heartburn

The Native American herb, high in salicylic acid, calms inflammation in the stomach, often working within a day or two, says Sheila Kingsbury. “For people on protein pump inhibitors who are desperate to get their heartburn under control without medication, I have them drink one cup of meadowsweet tea a day, and that’s all they need,” she says. “They’re always shocked that it’s so easy.”

DOSAGE: Pour 2 teaspoons of the dried herb in a cup of hot water; steep 20 minutes and drink once a day. (The slightly sweet tea has a mild almond flavor.)

PRECAUTIONS: Do not take meadowsweet if you’re allergic to aspirin.

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BEST FOR: Digestive problems

Psyllium is a tiny seed that contains mucilage, a soluble fiber that swells on exposure to water. For diarrhea, psyllium can absorb excess fluid in the gut. For constipation, psyllium adds bulk to stool, which presses on the colon wall and triggers the nerves that produce the urge to go. Also helps relieve hemorrhoids and helps remove toxins. May be used topically to draw out infections such as boils.

DOSAGE: Follow label directions; also available in capsule form.

PRECAUTIONS: When using psyllium, drink plenty of water; do not exceed the recommended dose. For help see: How to Make Sure You’re Drinking Enough Water.

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BEST FOR: Depression and pain

“Long before it was ever used for depression or anxiety, St. John’s wort was used as a pain reliever and an anti-inflammatory for muscle pains, burns, and bruises,” explains Rosemary Gladstar, adding that blending the oil with the alcohol-based tincture helps draw the active constituents into the skin for faster healing. For mild depression, St. John’s wort often works as well as some antidepressants but with fewer side effects. “We recently concluded a comprehensive review of the scientific literature on St. John’s wort, and 21 of 23 studies support it for mild to moderate depression,” says Blumenthal. It’s not clear if St. John’s wort is as effective as selective serotonin reuptake inhibitors (SSRIs) such as Prozac or Zoloft, but a 2013 Mayo Clinic overview states that scientific evidence supports its use for mild to moderate depression; for severe depression, the evidence remains unclear.

DOSAGE: For depression, studies showing benefits have used 600 to 1,800 milligrams a day; most have used 900 milligrams a day. For pain, make a liniment by mixing equal parts St. John’s wort tincture and St. John’s wort oil. (Most concoctions come in 2-ounce bottles.) Mix vigorously before using, apply topically to affected area (avoiding the eyes), and massage into skin as needed.

PRECAUTIONS: Stomach upset is possible, and St. John’s wort interacts with many drugs, including possibly reducing the effectiveness of birth control pills; so seek professional advice if you are taking a prescription medication. Depression requires professional care; ask your physician about St. John’s wort. May cause sensitivity to light.

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BEST FOR: Cough and cold

A really fun herb to pronounce, umckaloabo means “heavy cough” in Zulu. The South African herb is a powerhouse with antiviral and antibacterial properties, says herbalist Mark Blumenthal. “There are good clinical studies on the use of umckaloabo for treating bronchitis as well as tonsillitis,” he says, adding that taking umckaloabo at the onset of symptoms will bring relief within a day or two. Recent German studies of the preparation found that it significantly reduced symptoms and duration of colds and cough.

DOSAGE: Take as drops, syrups, chewable tablets or sprays. Follow package instructions.

Also consider adding these 30 Best Immune-Boosting Foods to your plate.

90,000 Benefits of Yellow Vegetables and Fruits – Health Info

To stay healthy, eat yellow vegetables and fruits

Bright colors can instantly improve your mood, especially if they are yellow vegetables and fruits. This sunny shade represents emotions such as happiness, joy and hope. When you purchase and eat yellow foods, you nourish your body, mind and soul and reap health benefits.

Yellow vegetables and fruits are a source of nutrition

Yellow vegetables and fruits are rich in carotenoids and bioflavonoids.The latter are a class of water-soluble plant pigments that act as antioxidants. Along with antioxidants, sunshine foods are also loaded with vitamin C. Research shows these nutrients can help your heart, digestion and immune system function, and improve your vision. Other benefits of eating yellow foods include healthy skin, quick wound healing, and stronger teeth and bones.

Yellow vegetables and fruits are one of the most natural types of food

The most common yellow vegetables and fruits are the following: lemons, pineapple, carambola, winter and summer pumpkins, yellow peppers, corn, quince, bananas (common and fodder ).

In addition to fruits and vegetables, yellow herbs can also benefit your health (be sure to check with your doctor before using any herbs for medicinal purposes). The herb canadian yellow root (another name is canadian hydrastis, lat. – Hydrastis canadensis ) can be used as a diuretic, astringent and antiseptic. It is also believed to be able to heal skin rashes. Yellow sorrel is often used to detoxify, improve blood composition, increase the flow of bile and other digestive juices that aid in the digestion of fatty foods.Dandelion is known to help control weight, relieve anemia, and reduce the likelihood of indigestion and gas.

Recipes that will help you to increase your consumption of yellow vegetables and fruits

• Bread with banana flour with cocoa
• Scented lemonade
• Fried feed bananas
• Stuffed baked peppers
• Dumplings / Chinese dumplings with shrimp, shrimp and pineapple salsa sauce
• Pumpkin flowers

Skirt steak with avocado and corn salsa salad

Canadian hydrastis, Goldenseal Herb, Nature’s Way, 800 mg, 100 capsules

Product code: 34596 Barcode: 033674137000

(delivery 10-20 days)

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Canadian Hydrastis, 400 mg, Gold enseal Herb, 400 mg

Canadian Golden Root (hydrastis) is a powerful tonic.Goldenseal is also known for its anti-catarrhal properties. These plants are often included in pharmaceutical medicines, used for rhinitis, mucous colitis, gastroenteritis, vaginal discharge. Hydrastis Canadian is considered one of the best natural antibiotics. For more detailed advice, you can contact the manager on the Biotus website.

Accept:

Take 1-2 capsules daily with food. For best results, use continuously for at least one week.

Other Ingredients:

Vegetable capsule (modified cellulose).

Warnings:

Keep out of reach of children.

Do not use if breastfeeding or pregnant.

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Public group 💰Most Useful blog about health and iherb

Ant tree bark or Pau D’Arco – useful properties and secrets of application

Hello friends!

❌C every day more and more people refuse to take chemical preparations and prefer herbal medicines.

❗Many of them are only means supporting the body, but there are also quite powerful ones that can defeat serious diseases, we just do not know about them.

🌴For example, the bark of an ant tree

❓What is it, when it is used, in what forms this natural antibiotic is sold, how it works, how to take it correctly, and who is better off to abandon this plant component, we will consider further.
________________________________
From this article you will learn:

1 The bark of the ant tree or Pau D’Arco1.
2 What is an ant tree? 3 Composition – the main active ingredients
4 Healing properties of the bark of an ant tree2
5 Forms of production and methods of application
6 Contraindications to use
_______________________________

What is an ant tree?

✅Ant tree (English Pau D’Arco, Latin Tabebuia heptophylla) – can be found in almost all countries of Central and South America.

✅It is most widespread in Venezuela, Colombia, Brazil (it is even sometimes called the “Brazilian tree”), and in Paraguay it is generally a long-recognized national plant.

✅ The tree has been used by man for a long time.

✅Strong high-quality furniture is made of it (but less and less often, because more affordable materials appear), used in the construction of houses.

✅ Flowers and seeds are very useful for animals and birds (hummingbirds simply adore them), and from the inner part of the bark they make a universal and very powerful medicine for people.

✅And also wonderful honey is obtained from it
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👏👍This is interesting! The average life span of an ant tree is 700 years.
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🍵Composition – main active ingredients

🌴👍👏The benefits of the ant tree bark are explained by its rich composition.

Priority attention should be paid to:

✔ vitamins of group B and C, which are necessary for the full functioning of the nervous system and increase immunity;
✔ calcium and iron, with a deficiency of which it is impossible to fully function the body and brain, the health of the blood and the digestive tract;
✔ selenium, which prevents the development of cancer cells, as well as
✔ manganese,
✔ beta-carotenes,
✔ iron,
✔ Fiber, etc.

✅The active ingredients of the ant tree bark are lapachol and lapachenol.

❗But they are found exclusively in the “living” part of the plant, therefore only the inner layer of the bark has medicinal properties
——-_ —————- _– ———_ ———— _———-

➕ Medicinal properties of the bark of the ant tree

Let’s consider in more detail how the bark of the ant tree is useful tree:

1⃣It is thanks to the work of active active substances that the bark of the ant tree is famous for its antibacterial effect.
2⃣Lapachol stops the multiplication of staphylococci, streptococci and other microorganisms. It is able to protect a person from the causative agents of malaria, dysentery and even tuberculosis.
3⃣An almost instantaneous positive effect is noted when taking preparations based on the bark during ARVI, influenza, herpes and even poliomyelitis.
4⃣ Medicines based on ant tree bark actively fight various infections and fungi, including vaginal and sexually transmitted infections, are effectively used in the treatment of allergies and autoimmune processes.
5⃣ Pain in joints and muscles goes away very quickly, normalization of the work of all internal organs, cleansing of the liver and kidneys is noted.
6⃣ Regular use of herbal antibiotic helps to remove toxins, heavy metals and waste products from the body.
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👉👉👉This is important!
❗ It has been proven that it is lapachol that can stop the development of malignant tumors and even completely destroy cancer cells, and it is also used to maintain the health of AIDS patients.
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Forms of release and methods of application

✅Now Foods, Pau D ‘Arco ant tree capsules (see the price on iherb👉 https://ru.iherb.com/pr/Now-Foods-Pau-D-Arco- 500-mg-250-Capsules / 718? Utm_source = anna34 & utm_medium = affiliate)

Most often there are 250 capsules of 500 mg each in a package.

Adults should take 1 capsule 1 time per day for preventive purposes and 2 times a day half an hour before meals for treatment.

Indications: prevention of colds and flu, chronic fatigue syndrome, bronchitis, tonsillitis, HIV infection, AIDS.

The parallel reception of echinacea or yellow root will help to enhance the effect.

Nature’s Answer Ant Tree Capsules, Pau d’Arco, 1000 mg, 90 Veggie Caps 1000-mg-90-Vegetarian-Capsules / 5433? Utm_source = anna34 & utm_medium = affiliate)
As a dietary supplement, take two (2) capsules twice daily with food or with water.

✅Sifted bark pieces from Frontier Natural Products (see prices on iherb 👉
https: // ru.iherb.com/pr/Frontier-Natural-Products-Cut-Sifted-Pau-d-Arco-Bark-16-oz-453-g/30740?utm_source=anna34&utm_medium=affiliate)
The volume is generally large. Almost a pound or so.

Taken in the form of tea. Add 4 tsp per liter of boiling water. collection, infused for a quarter of an hour. The taste is sour-bitter, but sweeteners should not be used.

Indications: for the prevention of infections and during rehabilitation after illnesses, 200 ml once a day.

During an exacerbation of diseases, you need to drink a liter per day in equal doses. After straining and cooling, it can be used for douching, especially when there is a need to restore the vaginal microflora.

✅Non-alcohol bark tincture (see prices on iherb👉 https://ru.iherb.com/pr/Herb-Pharm-Pau-D-Arco-Alcohol-Free-1-fl-oz-30-ml/12519? utm_source = anna34 & utm_medium = affiliate)

May be sold in containers of 30, 50 and 100 ml.

Many argue that this method of administration is significantly more effective than tablets and capsules.

The taste of the tincture is neutral, which allows it to be used even for children.

For the prevention of colds and flu, children are given 10-20 drops, dissolved in a glass of water three times a day (you can start from the age of 3).

In adults, the dose is higher: 1-2 ml three times a day. It can be used to treat warts externally. To do this, you need to make a lotion for the night for 10-20 days.

✅ Alcohol tincture (see the price on iherb👉 https: //ru.iherb.com / pr / Herb-Pharm-Pau-d-Arco-Inner-Bark-1-fl-oz-30-ml / 8651? utm_source = anna34 & utm_medium = affiliate)

Sold in containers of 30-100 ml. The dosage and indications are the same as for the non-alcoholic tincture, only the result comes faster.

❗Advice!
🍵 If, in parallel with the use of tincture, brew green tea (real), it will be possible to have a therapeutic effect on the nervous system, reduce irritability, restore the microflora of the intestines and genitourinary system.

✅ Ready made ant tree tea (see the price on iherb 👉
https://ru.iherb.com/pr/Now-Foods-Real-Tea-Pau-D-Arco-Caffeine-Free-24-Tea-Bags -1-7-oz-48-g / 39947? Utm_source = anna34 & utm_medium = affiliate)
You can drink this tea at least every day, moreover, several times a day. Prepare it in accordance with the instructions on the package.

Accepted for the prevention and treatment of colds and flu, coughs and lingering bronchitis, as well as to improve immunity.

_____________________________________

⛔Contraindications to use

It is difficult to overestimate the benefits of preparations prepared on the basis of ant tree bark, but not everyone can use its properties.

First of all, you should refuse to take it during pregnancy and breastfeeding (moreover, it should be borne in mind that harm will not be caused to the woman herself, but to the baby), as well as to people who have problems with the circulatory system.

Also, it is categorically impossible to combine reception with aspirin and other blood-thinning drugs.

The bark of the ant tree can be used as a dietary supplement, or it can completely replace a whole range of chemicals.

Just remember that self-medication is unacceptable.

The instruction may not always answer all questions, so be sure to visit a doctor and go through a full examination before starting an appointment.

I wish you health and longevity !!!

# immunity # longevity # flu treatment # children # health # coral antwood #iherb

Nature’s Way, Urinal, with cranberry – cranberry for bladder health

*** 15% Discount on Nature’s Way Brand!

Everyone knows about the benefits of cranberries for the prevention of inflammation of the bladder or cystitis ,
Previously, people cooked cranberry juice for these purposes, but there is no time for this, and it is problematic to have fresh, just picked cranberries on hand.
And now we have cranberries in capsules on Ayherb, and even enhanced with various useful herbs.

I’ll tell you about the natural bladder health supplement from the Nature’s Way brand .

Cranberry for Bladder Health:
Nature’s Way, Urinal with Cranberry, 100 Capsules

Our herbal collection is designed to support urinary tract health.

A full 600 mg serving (3 capsules) of Certified Cranberry Powder!
Also included in the composition are such herbs useful for the bladder as dandelion, marshmallow root, bedstraw, corn silk and yellow root.

The manufacturer recommends taking 3 capsules daily with a full glass of water.
That is, pay attention, it is recommended to drink plenty of water with cranberries!

Caution : Not recommended for pregnant or lactating women. Do not use if you suffer from acute inflammation of the gallbladder or bile ducts, or blockage of the bile ducts.

Briefly about the benefits of cranberries.
Cranberries play an important role in the health of the urinary tract.There is a lot of vitamin C in cranberries, it strengthens the immune system and increases the protective functions of the body. It has antipyretic, anti-inflammatory and tonic properties.
And most importantly, cranberries are high in tannin, which fights infections. If you use cranberries for prophylactic purposes, you can prevent the development of various infectious diseases, such as cystitis, and kidney stones.
The presence of potassium, magnesium and vitamin C has a beneficial effect on the functioning of the cardiovascular system.When cranberries are consumed, the walls of blood vessels are strengthened, their elasticity increases, and the risk of blood clots decreases. Eating cranberries is useful for hypertensive patients to lower high blood pressure.

Of course, this remedy does not cure cystitis (that is, inflammation that has already occurred)!
There is a doctor and other medicines for this.
But if you are prone to this kind of disease, these pills are a good remedy.
I bought this supplement for my mother, she often has it.Now she drinks various cranberry preparations, and ugh 3 times, she endured the winter calmly and did not even catch a cold.

*** My code EKA275 gives a 5% discount on any of your orders. To get a discount, enter my code in the shopping cart or just click on the link >>> EKA275

I’m on instagram @katya_greenblog

Many thanks to everyone who has already used my referral code!

Thank you for your attention and happy shopping!

All my entries in the Herbomania community follow this link >>> here

Beauty and benefit.An encyclopedia of medicinal plants for your garden (part 2)

Home> Flower garden> Beauty and benefits. An encyclopedia of medicinal plants for your garden (part 2)

October 24, 2014

The encyclopedia is being replenished! Landscape designer Olga Kirillova continues to talk about the medicinal properties of some popular garden plants and shrubs. The author describes them in alphabetical order and the first article (you can read it here) included a list from A to B.In the new publication, Olga presents 24 plants from G to K, and at the end, readers will find a diagram of the design of the coastal zone of a small pond using only medicinal plants. We give the floor to the author.

This article is a quick reference in which I have tried to include the maximum number of plants that could be used in gardening.

Quite often, having a small area of ​​the site, we want to transform it: create a group of shrubs or a mixborder, and maybe even an alpine slide.All these things can be used not only for decoration, but also for food or medicinal purposes. Some plants are probably already growing in your gardens, but you did not know that they can be very useful. And those plants that you, perhaps, have not yet met, will surprise you with their appearance and properties.

I really hope that this article will be useful for you and will reveal a lot of new things.

Witch hazel

It is a deciduous shrub, reaching a height of 3-6 meters, with very interesting yellow flowers.Suitable for landscaping background. It blooms in early spring and prefers sunny, open areas.

This plant is used to treat a wide variety of diseases. It helps well with pain and fatigue in the legs, sunburn, edema, varicose veins, acne. Stops bleeding quickly and relieves bruises. Basically, it is recommended to use it externally and carefully.

Forest geranium

Charming delicate perennial with purple flowers.Even after the geranium fades, a beautiful curtain of leaves remains. Delivers partial shade. Bloom from May to July.

It is a good remedy for inflammatory processes of UGN (otitis media, sinusitis, tonsillitis, tonsillitis). It is also used for heart problems, diabetes mellitus, neuralgic diseases and sciatica. It is an analgesic, antineoplastic and sedative agent.

Highlander

Its herb is used in medicine, perhaps as often as the herb St. John’s wort.Highlander preparations improve metabolism, cleanse the blood, strengthen the liver. Highlander is used as a diuretic, it perfectly reduces inflammation of the mucous membranes of the gastrointestinal tract, strengthens blood vessels and increases blood clotting.

The plant is very beautiful, especially decorative forms, and brings a little freshness and “something new” to the gardens. Now there are very beautiful varieties of highlander, which look amazing in the foregrounds of flower beds. The highlander prefers sunny locations.

Gentian

Any kind of gentian is beautiful, but my favorite is these blue clouds, which are especially prominent in rockeries.It also looks great when creating meadow landscapes in combination with grasses. Prefers disembarkation in lighted areas.

Gentian is used to increase appetite. It improves the formation and secretion of bile. A decoction of the roots increases immunity and strengthens the body.

Gravilat hybrid

This plant, which is popular in landscaping, is often used in rockeries or mixborders, looks good, framing gazebos and decorative bridges, and in gardens, gravilat is also planted in flowerpots.Good everywhere, but photophilous.

Lotions with crushed rhizome get rid of corns. Preparations from gravilat are used in the treatment of gastrointestinal inflammation, diarrhea, and liver diseases. It also has a hemostatic, analgesic and sedative effect. It is used for headaches, insomnia, fever.

Derbennik

Perennial light-loving plant, reaching a height of 80 cm. Crimson flowers attract attention. Suitable for the backgrounds of mixborders, highlighting this area.Very good in solitary planting. A dense, beautiful hedge is obtained from a loosestrife.

Flowers, leaves, roots and stems of the plant have medicinal properties. Derbennik preparations heal wounds, relieve inflammation, and are a good antibacterial and pain reliever. It is used for fever, headache, toxicosis, colds, as an antidote after tick and snake bites.

Datura harmless / Datura

Solanaceous annual plant, reaching a height of 50 cm.Has pretty pretty flowers. It is planted in lighted areas. Blooms until frost. Datura soothes, has antiseptic properties and treats bronchial asthma, bronchitis, colitis, bradycardia. Leaves are mainly used as raw materials. The plant is poisonous!

Oregano

Oregano, a fairly popular light-loving plant that is used as a seasoning, an additive to teas and for medicinal purposes. It’s always nice to have such a plant in your garden. In dishes, it goes well with dill, caraway seeds and cilantro.

Due to its medicinal properties, it is used as an antiseptic, anesthetic and sedative. Tea made from it is a good choleretic agent. It is not recommended to use oregano for pregnant women, people with diseases of the cardiovascular system, ulcers and hypertension.

Spruce

If only the smell of conifers is considered very beneficial to health, what can we say about the benefits of preparations made on their basis! Common spruce, or European spruce, has an excellent effect on the body.Due to its many medicinal properties, spruce is widely used in the treatment of various diseases.

The tops of twigs, needles, bark, resin, young cones have diuretic, antimicrobial, analgesic and restorative properties. Infusions are used for the prevention and treatment of respiratory diseases, coughs, bronchial asthma, tonsillitis, sinusitis. Spruce preparations help with urinary tract diseases. Decoctions are used for abrasions, purulent lesions, wounds, and baths give strength and relieve tension.

If you can write a separate article about the beneficial properties of this plant, then it is impossible to forget about its importance in gardening! I would say that no garden is complete without this plant. Spruce looks great as a tapeworm and is excellent in a group with other conifers and other ornamental plants. The abundance of varieties expands the boundaries of the use of this plant in landscape design.

Canadian yellowroot

A plant that thrives in partial shade.Creates a charming rug with a twist. It is good to plant it between trees and a fence, in a space where little grows due to a lack of light.

The root of the plant is used for medicinal purposes. By right, Canadian yellow root can be called a panacea for all diseases. Onn perfectly treats flu, vascular diseases, gastrointestinal diseases, colds. Helps with toxicosis, heals open wounds, relieves inflammation and helps with eczema and other skin diseases.

Creeping insect

Wonderful shade-tolerant ground cover plant.Looks great both on alpine slides and near bushes. Simple and beautiful padding in shady areas.

The whole plant is used for medicinal purposes. Tenacious is used for diarrhea, gallstone disease, rheumatism, inflammation of the appendages. It normalizes metabolism, treats sore throat, ulcers, wounds and bruises. Helps with baldness.

Curly honeysuckle

This plant in landscaping is gaining more and more popularity and not in vain! Climbing honeysuckle is an excellent, beautiful plant that perfectly braids a fence or trellises, with its help you can make a very beautiful and cozy place, the main thing is to plant it in the sun.Unusual flowers and berries that seem to lie on green plates will attract due attention and will undoubtedly interest any guest who visits your garden.

This plant is poisonous, but like all types of honeysuckle, it has medicinal properties. Leaves, flowers and berries are used for edema and diarrhea. They have disinfecting and diuretic properties.

Yasnotka / Zelenchuk

Lamb is a fairly popular plant for landscaping the garden or the area around it.Now there are various decorative shapes that will fit perfectly into any style. Lamb is shade-tolerant, decorative forms in the sun will quickly lose their beauty. But it can turn a dark area of ​​your garden into a cozy corner filled with light.

This herb is quite effective in relieving headaches, insomnia, heart and nervous system diseases. It is used to treat various skin diseases, stomach ulcers, diarrhea. It also helps with bronchitis, pneumonia and internal bleeding.

Strawberry

Of course, we are talking about aromatic forest strawberries, whose beneficial properties are known to everyone. Such strawberries find their place in the gardens of any summer resident. Her adorable bushes look good even in simple flower beds. Often it is planted in flowerpots and boxes, and for the winter it is buried right with them in the ground.

This is a very useful plant. Strawberries are used for low hemoglobin, vasoconstriction, gallstones, ulcers and gastritis. Strawberry decoctions normalize bowel function.Infusion from the root gargle the throat and mouth with sore throat. It also helps with skin diseases, fatigue, headaches, arthritis and obesity. In general, a remedy for any ailment!

Goldenrod / Solidago

A popular beautiful perennial plant from the Aster family that looks good on the background of mixborders and when planting along fences. Prefers open, sunny places.

In folk medicine, wild-growing solidago is used.Preparations from it have a diuretic effect. They are used for diseases of the kidneys and bladder, as an anti-inflammatory and very strong disinfectant. Pounded fresh leaves are applied externally for skin suppuration and boils.

Iberis bitter

Very beautiful ornamental plant. Iberis is great on alpine slides or in decorative plantings around stones. A low plant for the foregrounds of mixborders. For the best and more decorative growth, it should be planted in lighted areas.

Iberis preparations tone the heart, have anti-inflammatory, choleretic, antibacterial properties. It is a good wound healing agent. Decoctions are used for bronchitis, hepatitis, kidney disease, pneumonia.

Ivan-tea / narrow-leaved fireweed

An unpretentious perennial plant that grows in the wild in fields, clearings, on the edges, creating a luxurious pink mass. Increasingly, it can be found in garden landscaping in the background of mixborders or when landscaping a line along a fence.

The most popular tea made from fireweed is Koporye tea. It has long been drunk just like that, or taken as a medicine that was able to cure even seriously ill patients. The leaves are also used for food purposes in salads, meat dishes and soups. Bread was once baked from rhizome flour.

Infusions from this plant are able to cure ulcers, gastritis, sore throat. It helps with colds, headaches and insomnia, relieves fever. They are used to treat burns and wounds on the skin, and are used to prevent cancer

Irga

Shrub reaching a height of over 3 meters.It blooms with white flowers in May. Small branchy, therefore, when planting in gardens with small areas, the irga does not overload the space. It grows best in open, sunny locations. Thanks to the thin crown, it will grow harmoniously in a group with low shrubs. For the greatest openwork of the crown, it is recommended to thin out the trunks.

Irgi fruits contain a large amount of vitamins. They are used in food, making jam, compotes, jellies and other sweets from them. Gargle with juice. Infusions from the bark and leaves are used for diseases of the gastrointestinal tract and for the treatment of wounds with suppuration.Flower infusions are good for the heart

Hyssop officinalis

Perennial plant, reaching 80 cm in height. It grows and forms a lush bush. It is best to plant it in a mixborder, since after a very heavy rain or hail in the middle, the bush may fall apart and it will have to be cut. The plant prefers sunny places.

For medicinal purposes, the aboveground part in a blossoming state is used. Decoctions of hyssop are drunk for colds as an expectorant.Relieves inflammation of the upper respiratory tract and gastrointestinal tract, kills infection, has a diuretic effect. Topically used to treat stomatitis, skin lesions and wounds.

Kalgan / Erect cinquefoil

This is a medicinal type of Potentilla, the root of which is used as a spice. With a spicy, ginger-like aroma, the root is often used in cooking. This plant is very unpretentious. The medicinal galangal is distinguished by the presence of only four flower petals. It has anti-inflammatory, bactericidal, choleretic, wound healing, analgesic properties.As a spice, ground root stimulates digestion and increases appetite. Inhalation helps with bronchitis, and rinsing with an infusion of ground root relieves toothache.

Calendula

Very popular, unpretentious and actively propagating plant. Very often, calendula is planted in flower beds as a padding between perennial plants, since it reproduces well by seeds and fills empty space without problems.

Many people know about the medicinal properties of this plant.Calendula is used for hypertension, sore throat, various skin lesions, gastritis, ulcers and female diseases. Calendula ointment relieves inflammation, draws suppuration from wounds and inhibits the development of microorganisms.

Kalina

A beautiful shrub with white flowers. Viburnum fruits are bitter, but delicious jam is made from them. In gardens, it is good at solitary planting or in hedges. It is also used in groups with other plants. This is a very unpretentious and effective plant that responds well to a haircut.

She is treated for stomach ulcers, gastritis, colds, hypertension, diseases of the cardiovascular system. From the bark, drugs are made for cramps and bleeding. Kalina has soothing and strengthening properties of the nervous system.

Kandyk / Erythronium

A stunning beautiful plant that looks incomparable on alpine slides, rockeries and low flower beds. Prefers lighted areas, but tolerates light shading. The root system is a bulb, so erythronium does not conflict with other plants at all.It has beautiful leaves and very delicate charming flowers.

Kandyk bulbs contain a lot of starch, which is used as a strengthening heart and a stimulant. Also, preparations from it are a good laxative. But the most valuable thing that is obtained from this plant, and probably the rarest, is honey. Since kandyk blooms early enough (from April to early May), it is not possible to collect it by bees in all regions. But this honey cleanses the liver, removes toxins, strengthens the immune system, and improves the functioning of the pancreas.

Cardiospermum

Annual liana. This unpretentious climbing plant is very decorative, grows well and has medicinal properties.

Preparations made from cardiospermum are very effective. They treat rheumatism, digestive disorders, diseases of the bladder, bronchitis, pneumonia. In the form of lotions and ointments, they are used externally for dermatitis and eczema. The extract of this plant is added to cosmetic creams, as it has UV-protective properties.Prevents sunburn, allergic redness, chapping and cracking of the skin.

We plant greenery on the reservoir with medicinal plants

Many plots have at least a small pond. I propose the option of decorating a small reservoir exclusively with plants with medicinal properties. Beauty is usefully available to everyone!

The figure shows a pond of arbitrary shape with a round deck made of decking, playing the role of a decorative mooring, on which a bench is located.A path made of natural flat stone leads to this site. All landings in some places are lined with stones

Assortment of plants

1. Calamus ordinary – Acoruscalamus ‘Variegatus’
2. Althaea cannabis – Althaea cannabina
3. Anise ordinary – Pimpinella anisum
4. Astragalus membranous – Astragalus membranaceus
5. Astrantia major ‘Ruby Cloud’
6. Marsh Ledum – Rhododendron tomentosum
7. Elderberry – Sambucus racemosa ‘PlumosaAurea’
8. Heather ordinary varieties – Calluna vulgaris
9. Dennstaedtia punctilobula
10. Loosestrife rod-shaped – Lythrum virgatum
11. Rut-shaped loosestrife – Lythrum virgatum ‘RoseQueen’
12. Dirka marsh – Dirca palustris
13. White willow – Salixalba ‘Tristis’
14. Calendula officinalis ‘Cutting and Bending Mix’
15. Cossack juniper – Juniperus sabina ‘Variegata’
16. Chinese juniper – Juniperus chinensis ‘Kaizuka’
17. Weymouth Pine – Pinus strobus ‘Pendula’

This is how the landings in May will look like:

This is how the pond bank will look in July:

This is how the coastal zone will look in September:

Olga Kirillova, landscape designer

P.S. The editorial staff of the Green Portal project received a large number of positive reviews from readers who read the first article about the medicinal garden. Olga, thank you! We look forward to the next article!

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New on the site : section “Questions and Answers”.
Dear readers, if you want to learn more about landscape design and you have accumulated questions – ask us.Professionals will give a detailed and competent answer completely free of charge. We are waiting for letters by e-mail: [email protected].

Recommended Reading:

90,000 Top 11 Best Echinacea Supplements with iHerb

Echinacea strengthens the immune system, helps to regenerate skin cells and improves the functioning of many internal organs. In this article, we have compiled a selection of the best supplements from the echinacea echinacea site.

1. ChildLife, Essentials, Echinacea, Natural Orange Flavor, 30 ml
2. Now Foods, Echinacea, 400 mg
3. Gummiology, Gummiology, Gummiology, Propolis Echinacea Adult Chewable Tablets
4. Nature’s Way, Echinacea, 99.9% Free Alcohol, 30 ml
5. California Gold Nutrition, Echinacea, EuroHerbs
6. Sundown Naturals, Echinacea
7. Yogi Tea, Immune Support with Echinacea, Caffeine Free
8. Zand, Echinacea & Zinc, Herbal Lozenges, Super Cherry
9. Solgar, Complex echinacea and cat’s claw.
10. Nature’s Answer, Echinacea & Goldenseal, Alcohol Free
11. Natural Dynamix (NDX), Gummy Cuties
12. Echinacea Supplements: Buyer’s Guide. Questions and answers
13. Echinacea what is it
14. How to take
15. How does it affect immunity
16. Harm and benefits of Echinacea
17. Why it should not be for children
18. Can it raise blood pressure
19. How does it affect the heart
20. Can it cause allergies
21. Echinacea side effects
22. Where to buy Echinacea

ChildLife, Essentials, Echinacea, Natural Orange Flavor, 30 ml

Reference to product

The food supplement is suitable for children from 6 months to 1 year old.It has an excellent sweet taste as well as an orange aroma. Natural orange essential oil is responsible for the orange aroma, and fructose is used instead of sugar. Echinacea will help to strengthen the child’s immunity, which in turn will save him from off-season colds.

Pluses:

1. Convenient liquid form with pipette;
2. Pleasant sweet taste;
3. Suitable for children from 6 months;
4. Pleasant orange aroma;
5. Strengthens the immune system.

Now Foods, Echinacea, 400 mg

Reference to product

The supplement is intended for adults, where it is advised to take 2 capsules 4 times a day to achieve a therapeutic effect. Each capsule contains a purified echinacea root extract, which helps it more reliably and effectively support and strengthen the human immune system.

Pluses:

1. Strengthens the immune system;
2. Helps to cope with off-season colds;
3. Improves overall well-being.

Cons:

1. Waste consumption.

Gummiology, Gummiology, Adult Chewable Tablets with Propolis and Echinacea

Reference to product

Echinacea is presented in the form of gummies with the addition of propolis and vitamin C. This complex strengthens the immune system very well, supports human health during stress and hard work in difficult weather conditions.The sweets have a raspberry and citrus flavor that was obtained from natural raspberry and citrus extracts.

Pluses:

1. Delicious gelatinous candies;
2. Pleasant aroma;
3. Natural dyes;
4. Contains Vitamin C, Echinacea and Propolis;
5. Triple action to strengthen the immune system.

Nature’s Way, Echinacea, 99.9% Alcohol Free, 30 ml

Reference to product

Echinacea in liquid form with a convenient pipette for dosing will allow you to add it to tea or drink with clean water.The supplement is suitable for children from 6 to 12 years old and adults. Each age has its own instructions for the correct dosage of the drug. Echinacea will help promote health and immune system defenses.

Pluses:

1. Convenient pipette bottle;
2. Suitable for both children and adults;
3. Strengthens the immune system.

California Gold Nutrition, Echinacea, EuroHerbs

Reference to product

This preparation contains pure echinacea, which helps to strengthen the human immune system.The supplement capsules are colored green, which is natural. Depending on the age, the supplement is recommended to be taken in courses. Echinacea is recommended for use in winter.

Pluses:

1. Environmentally friendly product;
2. Easy to digest;
3. Strengthens the immune system;
4. Suitable for children (only need a doctor’s consultation).

Sundown Naturals, Echinacea

Reference to product

Capsules do not contain chemical colorants or GMOs.The capsules contain pure echinacea, which can be taken internally, either in tablets, or broken to make tea. Echinacea is suitable for strengthening the immune system for children and adults. Only in the case of children should a doctor be consulted.

Pluses:

1. Natural product;
2. Does not contain dyes and GMOs;
3. You can prepare tea from the contents of tablets.

Yogi Tea, Immune Support with Echinacea, Caffeine Free

Reference to product

Echinacea herbal tea comes without added caffeine.This tea is well suited for daily consumption. It boosts immunity, supports the respiratory system and tastes good. Along with echinacea, lemongrass and licorice are added to the tea.

Pluses:

1. Healthy tea with echinacea;
2. Delicious and aromatic;
3. Increases immunity;
4. Supports breathing.

Zand, Echinacea & Zinc, Herbal Lozenges, Super Cherry

Reference to product

Echinacea is presented in the form of a sweet pastille.The marshmallow also contains extracts of other herbs, brown rice, cane sugar and vitamin C. The marshmallow also contains menthol and zinc. Such lozenges are good for sore throat and increase immunity.

Pluses:

1. Sweet and tasty pastilles;
2. Contains echinacea, menthol, vitamin C;
3. Strengthens the immune system;
4. Helps to remove sore throat.

Solgar, Echinacea and Cat’s Claw Complex.

Reference to product

Vitamins contain echinacea complex and echinacea powder. Also added to it is the extract of the cat’s claw. The extracts are enclosed in vegetable capsules that do not contain colorants.

Pluses:

1. Contains Echinacea extract and cat’s claw;
2. Helps to strengthen the immune system;
3. Easy to digest.

Nature’s Answer, Echinacea & Goldenseal, Alcohol Free

Reference to product

The extract contains echinacea and yellow root.They are presented in liquid form, which will allow you to add the product to tea or water. The remedy strengthens the immune system well and increases the supply of energy.

Pluses:

1. Natural product;
2. Strengthens the immune system;
3. Increases the supply of energy.

Natural Dynamix (NDX), Chewy Cuties

Reference to product

Echinacea extract is presented in the form of chewable tablets, which are very pleasant and sweet in taste.Additional ingredients: sugar, milk, peanuts and more. Natural juice of fruits and vegetables is used as a colorant.

Pluses:

1. Pleasant taste;
2. Increases immunity;
3. Contains vitamin E, A and C.

Echinacea Supplements: Buyer’s Guide. Questions & Answers

Echinacea what is it

Echinacea is a perennial herb that comes from Asteraceae and has been eaten by humans since ancient times to improve health and fight various colds.

How to take

Echinacea comes in tablets, in liquid and loose form (herb). A different dose of echinacea is recommended for each age. Doctors advise that the best time to take the extract is in the morning:

• Children from 6 months to 1 year – 0.25 ml once every two days;
• Children from 1 year to 6 years old – 1 ml once every 2 days;
• Children from 6 to 12 years old – 1 ml 3 times a day;
• Teenagers from 12 to 18 years old – 2 ml 3 times a day;
• Adults – 25-35 drops 3 times a day.

Attention! The recommended doses are for informational and general purposes only. To clarify the exact amount of taking the drug for children or adults, it is worth consulting with a doctor in order to avoid the individual characteristics of the body.

How does it affect immunity

Echinacea affects the blood cells, which become stronger and stronger, therefore they can provide a more effective fight against colds ( Wikipedia ). It also saturates the human body and its immune system with iron, magnesium, selenium, calcium, potassium, silver, cobalt, zinc and other important and valuable components.

Harm and benefits of echinacea

Why can’t it be for children

Children should not be given adult echinacea that is cooked with alcohol. This option is allowed only for children from 6 years old. But from the age of 6 months to 1 year, and also older, it is recommended to select dry decoctions, or special formulations based on deionized water.

Can she raise the pressure

Echinacea can raise blood pressure, so this remedy is prohibited for people with arterial hypertension.

How does it affect the heart

Echinacea is rich in useful and valuable minerals, micro- and macroelements that strengthen the heart and help it work faster. Echinacea should be taken with caution or with the recommendation of a doctor for those people who have heart and vascular diseases.

Can it cause allergies

Due to individual intolerance to the extract, echinacea can cause allergies. Before taking it, it is worth doing a skin test (you need to buy a liquid form).Place a drop on the area of ​​your wrist and look at that area after a few hours. If the skin remains clean, then everything is in order, and if irritation and itching appear, then you should not use echinacea internally.

Side effects of Echinacea

• Echinacea may cause an allergic reaction due to individual intolerance to the product.
• Asthma;
• Bronchospasm;
• Leukopenia;
• Erythema;
• Encephalitis;
• Evans Syndrome;
• Sjogren-Larssen syndrome.

Echinacea where can you buy

Echinacea can be bought at any pharmacy. It is in the pharmacy that you purchase a quality product, without fear of counterfeiting, delay and additional impurities.

Rebuttal :: Beauty :: RBK Style

author

Julia Vakhonina, Anastasia Russkova

19 February 2019

Here was a text about Instagram blogger Elena Kornilova and biochemistry.We removed it and below explain why we did it.

Update from 04/23/2019. In February of this year, we released a text in which Elena Kornilova, positioning herself as a biochemist blogger, talked about vitamins, longevity and the principles of a healthy lifestyle.At the time of publication of the article, Elena Kornilova claimed that she was studying at the National University of Singapore, and also had a diploma of education from the Technical University of Munich and Anhalt University (she provided a photo of her student card and diplomas to our correspondent).

After the publication of the material, members of the RAS Commission on Counteracting the Falsification of Scientific Research, Pyotr Talantov and Mikhail Gelfand, contacted the editors, criticizing Kornilova’s activities and questioning the authenticity of her diplomas.

Together with Talantov and Gelfand, the editorial staff of RBC Style conducted an internal investigation to establish whether Elena Kornilova really has a specialized education. Inquiries were made to educational institutions and then official replies were received from the National University of Singapore and the Technical University of Munich. The representative of the first educational institution said that Elena Kornilova is not a student of the university, the representative of the second – that she did not study there and cannot be considered a genuine diploma.Having received this information, we decided to delete the text of the article. We apologize to the readers.

Peter Talantov, member of the RAS Commission on Countering the Falsification of Scientific Research, comments:

A significant part of what Elena Kornilova advises in her blog is not only not proven effective, but also unsafe. Let’s analyze only one of her posts with recommendations for those who are expecting a baby.

Elena suggests pregnant women to take 26 tablets a day.Some of them are drugs with unproven usefulness. Some – substances, the effect of which on pregnancy is not well understood. Some are just dangerous. Elena often neglects the recommended doses upward. If during pregnancy about 350 mg of magnesium is sometimes prescribed per day, then Kornilova recommends taking 900 mg at once. By the way, while the benefits of taking magnesium in pregnant women have not been found. Elena does the same with iodine. The doses recommended by the World Health Organization (WHO) are 250-500 mcg per day, Kornilova recommends 1000 mcg.She does the same with the criteria of the disease.

By the way, the norms of laboratory tests she calls differ from the generally accepted ones in such a way that as many people as possible would consider themselves sick. So she claims that the normal level of ferritin is at least 70-80 ng / ml, while for young women reading Elena’s blog, values ​​less than 70-80 ng / ml are widespread and completely normal. Among the products she is promoting for pregnant women are supplements containing chromium. Pregnant women are advised to avoid them! Research has shown that higher chromium concentrations in expectant mothers are associated with preterm birth and lower fetal weight.In the same scheme, there is a supplement containing the yellow root plant. It is rich in biologically active alkaloids, in particular berberine, which crosses the placental barrier and can cause kernicterus in the fetus, a brain damage caused by high levels of indirect bilirubin in the blood.

This problem may occur later, with breastfeeding. In rats, berberine has also been shown to induce uterine contractions and increase the risk of tumors. It’s important to remember that it’s not just berberine: WHO generally recommends avoiding herbal supplements during pregnancy without a doctor’s prescription.The same scheme assumes high doses of vitamins C and E. The World Health Organization warns that taking these supplements during pregnancy is undesirable, since they do not bring any benefit, but there is evidence of a twofold increase in the risk of premature rupture of the membranes.

In addition, vitamin E supplementation is in principle unsafe for most people and, instead of improving, may actually increase mortality. It is also worth remembering that drug interactions can occur between drugs.Substances that are safe in themselves can become harmful if taken at the same time. By recommending literally dozens of pills a day to her subscribers, Elena turns their body into a chemical factory with completely unpredictable consequences. Therefore, the mentions of side effects in the comments to her posts are not surprising. Please never use Instagram recommendations for treatment and consult your doctors if necessary.

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