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Helicobacter pylori forum. Salicylate’s Role in Suppressing H. pylori: A New Perspective on Bismuth Subsalicylate Treatment

How does salicylate contribute to H. pylori suppression. What is the mechanism behind bismuth subsalicylate’s effectiveness against drug-resistant H. pylori. Why are flagella important for H. pylori colonization. How does the immune system respond to bacterial flagella.

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The Unexpected Efficacy of Bismuth Subsalicylate Against Drug-Resistant H. pylori

The medical community was intrigued by a recent case study published by Geng et al. [1] in which bismuth subsalicylate successfully suppressed a drug-resistant Helicobacter pylori infection. This serendipitous observation has sparked a debate about which component of the medication – bismuth or salicylate – is responsible for its effectiveness.

The Crucial Role of Flagella in H. pylori Colonization

H. pylori’s ability to colonize the human gastric mucosa is largely dependent on its flagella. These whip-like structures enable the bacteria to move and navigate through the stomach’s harsh environment. How important are flagella for H. pylori’s survival? Research has shown that mice immunized with a vaccine targeting H. pylori flagella experienced significantly reduced colonization [3], highlighting the critical nature of these structures for the bacteria’s ability to establish and maintain infection.

Flagella as a Target for Immune Response

The human immune system has evolved sophisticated mechanisms to detect and respond to flagellated bacteria. What are some of these immune defenses?

  • Toll-like receptor 5 (TLR5): This receptor specifically recognizes flagellin, the primary protein component of bacterial flagella.
  • NOD-like receptor 4 (NLRC4): Upon detecting flagellin, this receptor activates the inflammasome, a key component of the innate immune response.

These immune mechanisms play a crucial role in corralling colonic flagellated microbiota [4], maintaining a delicate balance between tolerance and protection against potentially harmful bacteria.

Salicylate: A Potential Key Player in H. pylori Suppression

While the authors of the original study focused on the potential effects of bismuth, the salicylate component of bismuth subsalicylate deserves closer examination. What makes salicylate a promising candidate for H. pylori suppression?

Salicylate has been shown to reversibly block the synthesis of flagellin and flagella in enteric gram-negative bacteria [5]. This property suggests that salicylate may be an active ingredient against H. pylori, potentially disrupting the bacteria’s ability to colonize the stomach lining effectively.

The Dual Action of Salicylate

Salicylate’s effects on bacterial flagella may have two significant consequences:

  1. Direct suppression of H. pylori motility, hindering its ability to establish and maintain infection.
  2. Potential reduction of the inflammatory response triggered by flagellin recognition, offering additional protection to the host.

Implications for Future H. pylori Treatment Strategies

The hypothesis that salicylate plays a crucial role in the efficacy of bismuth subsalicylate against H. pylori opens up new avenues for research and potential treatment strategies. How might this information influence future approaches to managing H. pylori infections?

  • Development of targeted therapies focusing on flagella suppression
  • Exploration of salicylate-based treatments for drug-resistant H. pylori strains
  • Investigation of combination therapies that exploit both bismuth and salicylate properties

The Immune System’s Response to Flagellated Bacteria

Understanding the intricate relationship between the immune system and flagellated bacteria like H. pylori is crucial for developing effective treatments. How does the immune system recognize and respond to these microorganisms?

The immune system employs a multi-faceted approach to detect and control flagellated bacteria:

  • Pattern recognition receptors (PRRs) such as TLR5 and NLRC4 identify specific molecular patterns associated with flagella
  • Activation of innate immune responses, including inflammation and recruitment of immune cells
  • Stimulation of adaptive immunity, leading to the production of specific antibodies against flagellar antigens

This complex immune response serves to contain and eliminate potential pathogens while maintaining a balance with beneficial microbiota.

Exploring the Potential of Flagella-Targeted Vaccines

The success of flagella-targeted vaccines in reducing H. pylori colonization in mouse models [3] raises intriguing possibilities for human vaccine development. What are the potential advantages and challenges of this approach?

Advantages of Flagella-Targeted Vaccines

  • Specificity: Targeting a crucial component of H. pylori’s colonization mechanism
  • Potential broad-spectrum protection against various H. pylori strains
  • Possibility of preventing infection rather than treating established cases

Challenges in Vaccine Development

  • Ensuring long-lasting immunity in the harsh gastric environment
  • Addressing potential variability in flagellar antigens among different H. pylori strains
  • Balancing efficacy with safety and potential side effects

The Broader Implications of Salicylate’s Anti-Flagellar Effects

The discovery that salicylate can inhibit flagella synthesis in enteric gram-negative bacteria [5] has implications beyond H. pylori treatment. How might this property be exploited in managing other bacterial infections?

Potential applications of salicylate’s anti-flagellar effects include:

  • Development of novel antibacterial strategies for other flagellated pathogens
  • Exploration of combination therapies that target both bacterial motility and other cellular processes
  • Investigation of salicylate derivatives with enhanced anti-flagellar properties

This line of research could lead to new approaches in combating antibiotic-resistant infections and reducing reliance on traditional antibiotics.

The Interplay Between Bismuth and Salicylate

While this analysis focuses on the potential role of salicylate in suppressing H. pylori, it’s important to consider the synergistic effects of bismuth and salicylate in the bismuth subsalicylate compound. How do these two components work together to combat H. pylori infection?

Bismuth’s Antimicrobial Properties

Bismuth has long been recognized for its antimicrobial effects, including:

  • Disruption of bacterial cell walls
  • Inhibition of various bacterial enzymes
  • Interference with bacterial biofilm formation

Potential Synergy

The combination of bismuth’s direct antimicrobial action and salicylate’s anti-flagellar effects may create a potent dual-action treatment against H. pylori. This synergy could explain the effectiveness of bismuth subsalicylate against drug-resistant strains, as it targets multiple aspects of bacterial survival and colonization.

Future Research Directions

The hypothesis presented in this analysis opens up several avenues for future research. What are some key questions that need to be addressed?

  1. What is the relative contribution of bismuth and salicylate to H. pylori suppression in vivo?
  2. Can salicylate alone effectively suppress H. pylori infection?
  3. Are there other compounds that could enhance or mimic salicylate’s anti-flagellar effects?
  4. How does the suppression of flagella synthesis affect H. pylori’s ability to develop antibiotic resistance?
  5. Can the insights gained from studying bismuth subsalicylate lead to new treatment strategies for other flagellated pathogens?

Addressing these questions through rigorous scientific investigation could lead to significant advancements in our understanding and treatment of H. pylori infections and potentially other bacterial diseases.

The Importance of Continued Research on H. pylori Treatment

H. pylori infection remains a significant global health concern, affecting a large portion of the world’s population and contributing to various gastric disorders, including peptic ulcers and gastric cancer. Why is ongoing research into H. pylori treatment strategies crucial?

  • Rising antibiotic resistance: The increasing prevalence of drug-resistant H. pylori strains necessitates the development of alternative treatment approaches.
  • Global health impact: Effective H. pylori management could significantly reduce the incidence of gastric diseases worldwide.
  • Economic considerations: Improved treatments could lead to reduced healthcare costs associated with H. pylori-related complications.
  • Potential for broader applications: Insights gained from H. pylori research may inform strategies for combating other persistent bacterial infections.

The unexpected efficacy of bismuth subsalicylate against drug-resistant H. pylori serves as a reminder of the importance of revisiting and reevaluating existing treatments. It also highlights the potential for serendipitous discoveries to drive significant advances in medical science.

Integrating Traditional and Modern Approaches

As we continue to unravel the complexities of H. pylori infection and treatment, it’s essential to consider how traditional remedies like bismuth subsalicylate can be integrated with modern scientific understanding. This integration could lead to:

  • Development of enhanced formulations that maximize the benefits of both bismuth and salicylate
  • Creation of targeted delivery systems to improve the efficacy of these compounds in the gastric environment
  • Exploration of combination therapies that leverage the unique properties of bismuth subsalicylate alongside other antimicrobial agents

By combining the lessons learned from traditional treatments with cutting-edge research techniques, we may uncover new strategies for managing H. pylori infections that are both effective and less prone to resistance development.

The Role of Microbiome Research in H. pylori Management

As our understanding of the human microbiome grows, it’s becoming increasingly clear that the complex ecosystem of microorganisms in our bodies plays a crucial role in health and disease. How might microbiome research inform future approaches to H. pylori management?

Microbiome Considerations in H. pylori Treatment

  • Exploring the impact of H. pylori eradication on the overall gastric microbiome
  • Investigating potential probiotic interventions to support H. pylori treatment and prevent reinfection
  • Studying the interactions between H. pylori and other gastric microbes to identify potential synergistic or antagonistic relationships

By taking a more holistic approach that considers the entire gastric ecosystem, researchers may develop treatment strategies that not only target H. pylori but also promote a healthy, balanced microbiome that is less hospitable to pathogenic colonization.

Personalized Treatment Approaches

The growing field of personalized medicine may also play a role in improving H. pylori management. By considering factors such as an individual’s genetic makeup, microbiome composition, and immune response, clinicians may be able to tailor treatments for optimal efficacy and minimal side effects.

This personalized approach could involve:

  • Genetic testing to identify patients who may be more susceptible to H. pylori infection or complications
  • Microbiome analysis to guide the selection of appropriate antibiotics or alternative treatments
  • Immune profiling to predict treatment response and adjust interventions accordingly

As we continue to explore the complex interactions between H. pylori, the human host, and the gastric microbiome, we may uncover new targets for intervention and develop more sophisticated, personalized treatment strategies.

Ethical Considerations in H. pylori Research and Treatment

As with any area of medical research and treatment, the study and management of H. pylori infection raise important ethical considerations. What are some of the key ethical issues that researchers and clinicians must address?

Balancing Treatment and Microbiome Preservation

While eradicating H. pylori infection is often necessary to prevent serious complications, there is growing evidence that this bacterium may play a role in regulating stomach acid and potentially protecting against certain conditions. How do we balance the need for treatment with the potential long-term consequences of altering the gastric microbiome?

Antibiotic Stewardship

The rise of antibiotic-resistant H. pylori strains highlights the importance of responsible antibiotic use. Researchers and clinicians must consider:

  • Developing and promoting alternative treatment strategies to reduce reliance on antibiotics
  • Implementing stricter guidelines for H. pylori testing and treatment to avoid unnecessary antibiotic use
  • Educating patients about the importance of completing prescribed treatment courses to minimize the development of resistance

Global Health Equity

H. pylori infection disproportionately affects populations in developing countries. How can the global medical community ensure that advances in H. pylori treatment and prevention benefit all populations, regardless of socioeconomic status?

  • Developing cost-effective treatment options that are accessible in resource-limited settings
  • Promoting research that addresses H. pylori strains and treatment challenges specific to different geographic regions
  • Implementing public health initiatives to improve sanitation and reduce H. pylori transmission in high-prevalence areas

By addressing these ethical considerations, the medical community can ensure that advances in H. pylori research and treatment not only improve individual patient outcomes but also contribute to broader public health goals and global health equity.

Suppression of Helicobacter pylori Infection With Bismuth Subsalicylate: Was It the Bismuth or the Salicylate?

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Open Forum Infect Dis. 2022 Aug; 9(8): ofac413.

Published online 2022 Aug 11. doi: 10.1093/ofid/ofac413

Author information Article notes Copyright and License information Disclaimer

To the EDITOR—I read with great interest the publication by Geng et al [1] on their serendipitous observation that bismuth subsalicylate suppressed gastric infection in a patient with drug-resistant Helicobacter pylori. The purpose of this communication is to consider which of the components of the combination, or both, might be responsible for the efficacy of bismuth subsalicylate. The authors have reviewed the potential effects of bismuth. This letter focuses on the ability of the salicylate component to suppress flagella. There is convincing evidence that the motility of H pylori flagella has a key role in the colonization of the human gastric mucosa [2]. Mice immunized with a vaccine targeting H pylori flagella significantly reduced colonization [3]. The immune system has an extensive array of protective mechanisms to corral colonic flagellated microbiota [4]. These include the Toll-like receptor 5 that senses flagellin and the NOD-like receptor 4. On detection of flagellin, this receptor protein activates the inflammasome. Salicylate reversibly blocks the synthesis of flagellin and flagella in enteric gram-negative bacteria and may protect against an inflammatory response [5]. This supports the notion that the salicylate component of bismuth subsalicylate is an active ingredient against H pylori. This hypothesis is offered to stimulate further work in this important field.


Potential conflicts of interest.
The author: No reported conflicts.

The author has submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

1.
Geng C, Prokesch BC, Vemulapali R. Successful suppression of drug-resistant Helicobacter pylori infection with bismuth subsalicylate. Open Forum Infect Dis 2022; 9:ofac165. [PMC free article] [PubMed] [Google Scholar]

2.
Spohn G, Scarlato V. Motility, chemotaxis, and flagella. In: Mobley HLT, Mendz GL, Hazell SL, eds. Chapter 21: Helicobacter pylori: physiology and genetics. Washington, DC: ASM Press; 2001. [PubMed] [Google Scholar]

3.
Skene C, Young A, Every A, Sutton P. Helicobacter pylori flagella: antigenic profile and protective immunity. FEMS Microbiol Immunol 2007; 50:249–56. [PubMed] [Google Scholar]

4.
Ley RE, Gewirtz AT. Corralling colonic flagellated microbiota. N Engl J Med 2016; 375:85–7. [PubMed] [Google Scholar]

5.
Kunin CM, Tong HH, Bakaletz LO. Effect of salicylate on expression of flagella by Escherichia coli and Proteus, Providencia, and Pseudomonas spp. Infect Immun 1995; 63:1796–9. [PMC free article] [PubMed] [Google Scholar]


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Open Forum Infectious Diseases, Volume 9, Issue 8, August 2022, ofac413, https://doi. org/10.1093/ofid/ofac413

Published:

11 August 2022


Article history

Received:

29 July 2022

Editorial decision:

05 August 2022

Accepted:

09 August 2022

Published:

11 August 2022

Corrected and typeset:

22 August 2022



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    Calvin M Kunin, Suppression of Helicobacter pylori Infection With Bismuth Subsalicylate: Was It the Bismuth or the Salicylate?, Open Forum Infectious Diseases, Volume 9, Issue 8, August 2022, ofac413, https://doi. org/10.1093/ofid/ofac413



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To the EDITOR—I read with great interest the publication by Geng et al [1] on their serendipitous observation that bismuth subsalicylate suppressed gastric infection in a patient with drug-resistant Helicobacter pylori. The purpose of this communication is to consider which of the components of the combination, or both, might be responsible for the efficacy of bismuth subsalicylate. The authors have reviewed the potential effects of bismuth. This letter focuses on the ability of the salicylate component to suppress flagella. There is convincing evidence that the motility of H pylori flagella has a key role in the colonization of the human gastric mucosa [2]. Mice immunized with a vaccine targeting H pylori flagella significantly reduced colonization [3]. The immune system has an extensive array of protective mechanisms to corral colonic flagellated microbiota [4]. These include the Toll-like receptor 5 that senses flagellin and the NOD-like receptor 4. On detection of flagellin, this receptor protein activates the inflammasome. Salicylate reversibly blocks the synthesis of flagellin and flagella in enteric gram-negative bacteria and may protect against an inflammatory response [5]. This supports the notion that the salicylate component of bismuth subsalicylate is an active ingredient against H pylori. This hypothesis is offered to stimulate further work in this important field.

Notes

Potential conflicts of interest. The author: No reported conflicts.

The author has submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

References

1

Geng

C

,

Prokesch

BC

,

Vemulapali

R

.

Successful suppression of drug-resistant Helicobacter pylori infection with bismuth subsalicylate

.

Open Forum Infect Dis

2022

;

9

:

.

2

Spohn

G

,

Scarlato

V

. Motility, chemotaxis, and flagella. In:

Mobley

HLT

,

Mendz

GL

,

Hazell

SL

, eds.

Chapter 21: Helicobacter pylori: physiology and genetics

.

Washington, DC

:

ASM Press

;

2001

.

3

Skene

C

,

Young

A

,

Every

A

,

Sutton

P

.

Helicobacter pylori flagella: antigenic profile and protective immunity

.

FEMS Microbiol Immunol

2007

;

50

:

249

56

.

4

Ley

RE

,

Gewirtz

AT

.

Corralling colonic flagellated microbiota

.

N Engl J Med

2016

;

375

:

85

7

.

5

Kunin

CM

,

Tong

HH

,

Bakaletz

LO

.

Effect of salicylate on expression of flagella by Escherichia coli and Proteus, Providencia, and Pseudomonas spp

.

Infect Immun

1995

;

63

:

1796

9

.

© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact [email protected]

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Helicobacter pylori – an epidemic of the 21st century or a bloated fake of gastroenterologists? – Personal experience on vc.

ru

Hello everyone, after writing my article about how I went to the doctors to no avail and treated the symptoms and ruined my health, and not the root of the problem, I was inundated with messages asking for help with advice.

45676
views

I have repeatedly said that we are all individual and there is no one single method that would help everyone, even with seemingly common symptoms at first glance. Therefore, I will try to give you the right direction in solving your problems, and not cure you, since I am not a doctor. And then everything will be in your hands. I did it and you can do it 🙂

I want to stress the point that no one but you is interested in your health. Therefore, I urge everyone to start treating him more responsibly. And unfortunately, I understand that all this is “lyrics”, because people do not learn from the mistakes of others. As the saying goes, “Until the rooster crows.”

So, let’s move on to the main topic, namely Helicobacter pylori.

Is it really as scary as doctors try to present it to us?

Let’s turn to Russian-language sources to understand how this bacterium is described in our RU segment.

And what do we see there? Some horror stories, how terrible and merciless this bacterium is.

Stomach cancer ranks fourth among oncological diseases in men and women. In 90% of cases, it is caused by the bacterium Helicobacter pylori. This infection is one of the most common in Russia, it causes chronic inflammation of the gastric mucosa (that is, active gastritis) in all infected people. For a long time, it may not manifest itself in any way, but at the same time provoke the development of an ulcer, adenocarcinoma, or stomach maltoma. In a special risk zone are people whose relatives have already encountered these diseases. They definitely need to be examined for Helicobacter pylori infection and, if it is found, treated.

Dmitry Bordin, CHIEF GASTROENTEROLOGIST OF MOSCOW

Also, articles are full of headlines that 50,60 or even 70% of the world’s population are INFECTED with Helicobacter pylori infection. With the same success, you can write articles about the fact that we are infected with lacto and bifidobacteria. Since the essence will be the same.

But for some reason, no one talks about such things that this bacterium was transferred from pathogenic to opportunistic and that 90% of carriers of this bacterium do not experience any negative symptoms.

What does opportunistic pathogenic mean? And this means that this bacterium is present in moderate amounts in a healthy human body, and only under certain conditions, when its number increases dramatically, does it begin to cause discomfort to its carrier.

Among other things, there are studies that prove that the bacterium Helicobacter pylori protects us from certain types of cancer.

We are at the forefront of understanding how the human microbiome works. But many scientists compare it to a complex tropical jungle ecosystem, where a huge number of plants and animals are in a state of constant confrontation, but at the same time in balance. And as soon as this balance is disturbed, problems begin.

So in our body, to maintain health, a balance is needed.

To treat or not to treat Helicobacter pylori?

In my opinion, the answer is obvious – treat only when it makes you uncomfortable. Instead of following the instructions of doctors who advise taking 2 weeks of antibiotics for the whole family when one family member is diagnosed with an infection.

I know many cases when such treatment was prescribed to all family members, although only one person had symptoms…

How exactly it should be treated, we will analyze a little later.

The main question that people should ask themselves when they feel the harmful effects of this bacterium is “What am I doing wrong? Why did the bacterium grow in me and poison my life?”

To answer this question, you need to understand the mechanism of the influence of bacteria on our body.

In simple terms, our immunity knows perfectly well which bacteria and where they should live. And as soon as one of these conditions is violated, our immunity begins to correct this misunderstanding.

It can be compared with a forester who monitors the state of the forest, and if, for example, there are too many wolves (pathogenic bacteria) and they end up where they should not be, he calls hunters (T-lymphocytes) for help, who begin to shoot them for maintaining the balance of the forest ecosystem.

When this internal war takes place, the territory in which it takes place suffers, we call this condition inflammation.

In the case of helicobacter pylori, the following happens, this bacterium attaches itself to the epithelium of our stomach and begins to destroy the mucin contained in the mucus, through the release of the enzyme mucinase.

And for example, after taking antibiotics, the beneficial bacteria that controlled the number of helicobacter pylori decreased, which gave room for its reproduction. As a consequence, the mucous membrane loses the ability to protect the walls of the stomach from hydrochloric acid, their ulceration occurs, and the production of protective mucus decreases due to damage to the glands.

Damaged gastric mucosa has increased absorption, which leads to intoxication of the whole organism.

Treatment

  • The most important thing is to start populating the gastrointestinal tract with helicobacter pylori antagonists, they are saccharomyces boulardii, lactobacillus reuteri, bacillus subtilis.
  • Add prebiotics to your diet, which feed on our beneficial bacteria and secrete short-chain fatty acids, which in turn promote healing of the gastrointestinal mucosa.
  • For additional support of the body with probiotics and metabiotics (waste products of beneficial bacteria), it is advisable to start making homemade yogurt and have kombucha, as well as any fermented foods: sauerkraut, kimchi, natto, tempeh, etc. but start with small portions and see how your digestive tract reacts to them.
  • Essential oils that have long proven themselves as excellent antibacterial and anti-inflammatory agents. Oils with proven effectiveness against Helicobacter: oregano oil, peppermint oil, carrot seed oil, grapefruit seed extract.
  • Mastic resin
  • Vitamin C
  • Any collection of herbs that have anti-inflammatory and antibacterial effects.
  • Curcumin
  • For adequate bile flow, it is desirable to add natural cholagogues.
  • To reduce intoxication, add any sorbent, but personally I would advise zosterin. Drink every day at night.
  • Helicobacter affects the acidity of the stomach in different ways, some strains increase, others decrease, therefore, in case of increased acidity, you should be more careful about products that increase it.
  • Add any enzymes to reduce the load on the pancreas and if you see undigested food in the stool.
  • Mandatory diet, excluding all preservatives, fast food, fried, smoked, all fast carbohydrates. As for food, try to eat more fresh vegetables and fruits, there are many contradictory diets, so you should not rely on them. Choose your diet individually for yourself, the main thing is that it has a lot of fiber.
  • Smoking and alcohol are prohibited for the entire period of treatment, at least 3 months.
  • Add minimal physical activity, anything, exercises in the morning, walks in the evenings, minimal walks during working hours.
  • Contrast shower for general immunity strengthening, start gradually.

Here I tried to collect the most complete information about effective ways to combat Helicobacter. This does not mean that you need to run headlong and buy everything from this list. Try, experiment, select, listen to your body.

Unfortunately, probiotic formulations do not have a long-term effect, they simply do not get fixed in our gastrointestinal tract and leave it naturally over time.

When I wrote in my article about rolling back my result, this is exactly what happened. Therefore, to consolidate the results, it is very important to adjust your diet.

Food

As I wrote earlier, fiber is the main source of food for our beneficial microflora. Which is found in fresh vegetables and fruits. The more fibrous structure of what you eat, the more fiber these foods contain.

Dietary fiber

The daily intake of dietary fiber has been raised several times, and now it corresponds to the value of 38 grams for men and 30 grams for women. But even this parameter varies from many things, such as body weight and physical activity. Personally, I eat a lot more.

There are people who are satisfied with taking pills, bringing their condition back to normal and again indulging in all serious. This is from the category of how to thump to a semi-conscious state, and then order yourself a dropper to cleanse your body of the half-life products of alcohol. I know such people who order a doctor for themselves at home in advance, the next day, when they know that they will drink. Everyone’s choice, who am I to judge anyone? 🙂

I understand that rebuilding my lifestyle and habits is a very difficult task, I myself am far from perfect, but I strive to create the most comfortable conditions for my body so as not to get kickbacks that I got earlier.

Personally, I discovered legumes for myself: chickpeas, lentils, mung beans, soybeans, beans. Which replaced pasta, white rice, potatoes and other harmful side dishes.

Total

In previous articles, I shared my experience of how I overcame the manifestations of the disturbed imbalance of my microflora. It was a single specific case.

Here I have tried to put together all the information currently available to help you fight helicobacter pylori.

All information is taken from open sources, mainly from pubmed. I didn’t attach links purposefully, since it takes a lot of time and “agrits” a bunch of dissatisfied personalities who are trying to “attach” to every word and prove my wrongness in some way and demand articles that will prove that black is black . Although I repeated a million times that all people are individual and what helped me, it is not at all a fact that it will help another.

Whether or not you follow my advice is an individual matter.

P.S. I ask in advance everyone who will write to me in a personal with requests to give advice or help in some way. Immediately write as detailed as possible what exactly worries you and ALL the symptoms.

As I wrote in the previous series of articles, we are developing an algorithm that, based on the data received, will be able to give advice on lifestyle adjustments, goal achievement or treatment. At the moment, we have started testing a block that makes recommendations based on the patient’s history, so you have a chance to participate 🙂

10 foods that Helicobacter pylori does not like

Content

  • 1 Foods that help fight Helicobacter pylori: a list of undesirable foods
    • 1. 1 Unripe fruits
    • 1.2 Coffee and Helicobacter pylori ori
      • 1.2.1 Coffee may aggravate infection Helicobacter pylori
    • 1.3 Alcoholic beverages: what you need to know about the effect on Helicobacter pylori?
    • 1.4 Flour products are not recommended for infection with Helicobacter pylori
    • 1.5 Why does Helicobacter pylori dislike fatty foods?
    • 1.6 Inappropriate foods for Helicobacter pylori
      • 1.6.1 Hot spices and sauces
    • 1.7 Dairy products that are not recommended for use in the presence of Helicobacter pylori infection
    • 1.8 Citrus Fresh foods and Helicobacter pylori
    • 1.9 Canned food and Helicobacter pylori
    • 1.10 Chocolate and Helicobacter pylori
    • 1.11 Where can I find more information about foods that Helicobacter pylori doesn’t like?
    • 1.12 Related videos:
    • 1.13 Q&A:
        • 1.13.0.1 Which foods are the most effective against Helicobacter pylori?
        • 1. 13.0.2 How often do you need to eat foods to kill Helicobacter pylori?
        • 1.13.0.3 Can eating foods that Helicobacter does not like lead to side effects?
        • 1.13.0.4 Can the products from the article be used as a prophylaxis for H. pylori infection?
        • 1.13.0.5 Can the products in the article make stomach ulcers worse?
        • 1.13.0.6 Can Helicobacter disliked foods replace medicines to treat an infection?

Find out what foods to avoid in your diet to reduce the amount of Helicobacter pylori in the stomach and avoid health problems. Read the article on the site and make the right menu for yourself!

Helicobacter pylori is a bacterium that lives in the human stomach and can cause various diseases such as gastritis, stomach ulcers and even cancer. The main cause of infection is certain foods that facilitate its growth and spread.
Therefore, it is important to know which foods to limit or exclude from your diet so as not to promote the growth of H. pylori infection. In this article, we will look at 10 foods that Helicobacter pylori does not like and can help in the fight against this bacterium.
The first food that is not recommended for people with Helicobacter pylori infection is red meat. It is high in saturated fat, which can have a negative effect on stomach health.
It is also worth paying attention to coffee consumption. It contains an acid that can irritate the lining of the stomach and increase the symptoms of an infection. However, there are certain types of coffee that do not have this effect, which we will also cover in this article.

Unripe fruit

Helicobacter pylori may not tolerate unripe fruit. For example, bananas that are not yet fully ripe can cause stomach discomfort. The same applies to some other fruits such as apples, pears or peaches.

Therefore, for those who have H. pylori, it is recommended to avoid unripe fruits and eat ripe fruits that contain less starch and acid. In this case, you should take into account the individual characteristics of the body and consult a doctor before changing the diet.

Coffee and Helicobacter pylori

Coffee may aggravate Helicobacter pylori infection

Coffee is a favorite drink of many people. However, in the presence of Helicobacter pylori infection, its use can adversely affect health.

Coffee is an acidic beverage that can increase stomach acid and worsen symptoms of gastritis, ulcers, and other diseases associated with H. pylori infection.

Moreover, coffee contains caffeine, which stimulates the secretion of gastric juice, which can also lead to a worsening of the condition in the presence of a Helicobacter pylori infection.

  • People suffering from Helicobacter pylori infection are advised to limit or avoid coffee consumption.
  • If you can’t give up coffee altogether, you should definitely take milk or other dairy products with it to reduce its acidity and reduce the effect on the stomach.

Alcoholic beverages: what you need to know about the effect on Helicobacter pylori?

Helicobacter pylori, which causes stomach and duodenal ulcers, does not like alcohol. Some people aim to kill the bacteria by drinking alcoholic beverages to do so, but this can have the opposite effect.

If you want to get rid of H. pylori, it is best to give up alcohol and see a doctor for advice. Your doctor can recommend the right medications and diet to help eradicate Helicobacter pylori and restore your stomach and intestines to health.

Flour products are not recommended for infection with Helicobacter pylori

Helicobacter pylori is a disease that causes inflammation of the stomach and duodenum. One of the most effective ways to fight this disease is to take care of your diet. Refusal of certain products contributes to the destruction of Helicobacter pylori and reduces the treatment time.

Most flour products contain a large amount of carbohydrates, which contributes to the active reproduction of Helicobacter pylori. Therefore, in the presence of this disease, it is recommended to refuse them.

If you cannot refuse baked goods, it is recommended to choose only fresh, low-fat and low-calorie breads and cookies, and avoid pastries with cream, chocolate and other sweets.

  1. Wheat flour. Wheat flour is the main ingredient in many flour products such as bread and pasta. However, Helicobacter pylori loves carbohydrates, so eating foods made from wheat flour is not recommended.
  2. Buns and cakes. Buns and muffins contain a lot of sugar and fat, which helps Helicobacter pylori multiply. Avoiding muffins and muffins will help avoid exacerbating gastrointestinal symptoms and speed up healing.
  3. Macaroni and pasta. Most pastries contain a lot of carbohydrates that cause the stomach’s favorite disease, Helicobacter pylori. Therefore, avoiding their use in case of infection with Helicobacter pylori is recommended.

Why does Helicobacter pylori dislike fatty foods?

Helicobacter pylori is a bacterium that lives on the gastric mucosa, causing various diseases. It is not harmful to all foods, but it is known that some of them contribute to its reproduction. Such a product is fatty foods.

Helicobacter pylori does not live in the intestines, so it cannot digest fat, which is found in large quantities in fatty foods. As a result, this leads to a distortion of the acid-base balance in the stomach, which favors the reproduction of Helicobacter pylori and impairs the functioning of the organ.

Fatty foods can also cause stomach problems such as ulcers or gastritis, which can also be caused by the presence of Helicobacter pylori. Therefore, if you want to get rid of this bacterium or prevent it from multiplying in your stomach, it is recommended to reduce your intake of fatty foods and switch to a healthier diet.

Unacceptable foods for Helicobacter pylori

Hot spices and sauces

Pungency and acidity are what can lead to exacerbation of symptoms in an infection with Helicobacter pylori. Therefore, it is better to limit the use of hot spices and sauces containing vinegar and pepper.

These products include:

  • Ketchup is a tomato sauce that contains vinegar, which can cause severe stomach pain and also promote bacterial growth.
  • Mustard is a spicy spice that can irritate the stomach lining and cause pain. There may also be additives that adversely affect the digestive system.
  • Spices (red pepper, garlic, onion) – decorate dishes, but can cause discomfort and exacerbate the symptoms of infection with Helicobacter pylori. It is recommended to use them in limited quantities.

In general, it is best to refrain from using hot spices and sauces during illness and when the digestive system is weakened. This will help reduce the load on the gastric mucosa and prevent an exacerbation of the infection.

Dairy products that are not recommended in the presence of Helicobacter pylori infection

Helicobacter pylori is a bacterium that can lead to various diseases of the retroperitoneal gastrointestinal tract, including gastritis and stomach ulcers. The use of certain foods can contribute to the reproduction of this bacterium and worsen the condition of the sick person.

Dairy products are often recommended for use in diseases of the gastrointestinal tract, but not all of them are useful in the presence of Helicobacter pylori infection.

  • Raw or low-fat dairy products such as milk, sour cream, and yogurt can increase stomach acid and encourage Helicobacter pylori to multiply. It is recommended to reduce the consumption of these foods when sick.
  • Fatty cheeses and creams should also be limited, as they can aggravate the symptoms of gastritis and stomach ulcers.
  • Fruit yoghurts may contain high amounts of sugar, which can disturb the pH of the stomach and promote bacterial growth.
  • Fatty cheeses should also be limited, as they can aggravate the symptoms of gastritis and stomach ulcers.

In the presence of Helicobacter pylori infection, it is desirable to reduce the consumption of dairy products and limit mainly low-fat and natural dairy products. However, it is important to consult a doctor and make an individual diet for the treatment of the disease.

Citrus products and Helicobacter pylori

Helicobacter pylori is a bacterium that can cause stomach ulcers and dozens of other health problems. To prevent the development of bacteria, you need to make changes to your diet. One such change is the exclusion of citrus products.

If you find it difficult to completely give up citrus products, you can use them in limited quantities and in combination with other products. For example, add lemon or lime to vegetable salads to enhance their flavor and aroma. Avoid eating citrus fruits on an empty stomach, but rather add them as a dessert after a full meal.

Canned food and Helicobacter pylori

Helicobacter pylori is a bacterium that can lead to various diseases of the gastrointestinal tract. It can be transmitted through the faecal-oral route, as well as through shared objects and food. Various foods can affect the development and growth of bacteria, including canned foods.

Canned foods such as meat, fish, and vegetables may contain preservatives and other additives that may be harmful to the health of the body. They may also contain high levels of sodium and sugar, which can increase the growth of bacteria, including Helicobacter pylori.

If you want to avoid the risk of developing Helicobacter pylori infection, you should avoid canned foods, especially meat and fish. Instead, eat fresh fruits and vegetables, home-cooked animal proteins. Remember that proper nutrition helps to improve health and protect your body from various diseases.

Chocolate and Helicobacter pylori

Chocolate is a favorite treat for many people around the world. It contains antioxidants and can boost your mood. But what about the compatibility of chocolate with the bacterium Helicobacter pylori?

Research has shown that chocolate may be harmful to those with Helicobacter pylori infection. Chocolate contains theobromine, which can increase the amount of acid in the stomach, which can exacerbate the symptoms of gastritis and stomach ulcers.

Therefore, if you have a Helicobacter pylori infection, it is best to avoid eating chocolate or eat it in small amounts so as not to aggravate your symptoms.

Where can I find more information about foods that Helicobacter pylori doesn’t like?

If you are interested in learning more about foods that Helicobacter pylori does not like, there are many resources and sources where you can find more information.

You can also contact your doctor or dietitian for specific recommendations and advice for your case.

Finally, don’t forget about medical and health books and magazines, which often contain articles and materials on the treatment of H. pylori and its relationship to diet and nutrition.

Ultimately, getting the right information about foods that can affect H. pylori will help you make better decisions about your health and well-being.

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Q&A:

Which products are the most effective against Helicobacter pylori?

The article, on the contrary, talks about 10 foods that Helicobacter pylori does not like, and not about which foods fight this bacterium. However, these foods include garlic, honey, cranberries, and mangosteen, which may have some effect on this bacterium.

How often do you need to eat foods to kill Helicobacter pylori?

There is no single answer, since the effectiveness of the destruction of Helicobacter pylori depends on many factors, including the number of bacteria in the body, the state of the digestive system, concomitant diseases, and others. However, eating foods that Helicobacter does not like must be included in the regular diet in order to achieve the best effect.

Can eating foods that Helicobacter does not like lead to side effects?

In most cases, eating foods that H. pylori dislike does not cause side effects. However, sometimes people may experience stomach discomfort or allergic reactions to certain foods. Therefore, if you are allergic to any of the products, you should not consume them in large quantities.

Can the products from the article be used to prevent Helicobacter pylori infection?

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