How does Topamax work for weight loss. Is Topamax FDA-approved for weight management. What are the potential risks and benefits of using Topamax off-label for weight reduction. How effective is Topamax compared to other weight loss medications.

Understanding Topamax: More Than Just an Anticonvulsant

Topamax, known generically as topiramate, is a medication primarily prescribed for epilepsy and migraine prevention. However, its reputation extends beyond these approved uses due to a notable side effect: weight loss. This unexpected benefit has sparked interest in its potential as a weight management tool, despite lacking official FDA approval for this purpose.

What is Topamax?

Topamax is an anticonvulsant medication that works by altering electrical activity in the brain. It’s FDA-approved for:

• Treating epilepsy
• Preventing migraine headaches
• Managing alcohol use disorder

The Weight Loss Connection: How Topamax Affects Body Mass

While not its primary function, Topamax’s impact on weight has garnered significant attention. But how exactly does it contribute to weight loss?

Mechanisms Behind Topamax-Induced Weight Loss

Topamax influences weight through multiple pathways:

1. Appetite suppression: It reduces feelings of hunger, leading to decreased food intake.
2. Metabolic boost: Some studies suggest Topamax may increase the body’s metabolic rate.
3. Taste alterations: It can change how food tastes, potentially reducing the desire for certain foods.

Clinical trials have shown that approximately 6-17% of Topamax users experience weight loss. Dr. Kuldeep Singh, a renowned weight loss surgeon, notes that most individuals see moderate weight reduction when using this medication.

Topamax Dosage for Weight Management: Finding the Right Balance

Determining the optimal Topamax dosage for weight loss is challenging, as this use is off-label. However, insights from its use in treating binge eating disorders provide some guidance.

Typical Dosage Range

When prescribed off-label for weight management, Topamax dosing generally follows these guidelines:

• Starting dose: 25-50mg once daily
• Maximum dose: Rarely exceeds 200mg per day
• Titration: Dose is slowly increased over weeks until desired weight loss is achieved

It’s crucial to note that higher doses don’t necessarily equate to greater weight loss. The goal is to find the lowest effective dose that balances benefits with potential side effects.

Safety Considerations: Is Topamax a Viable Weight Loss Option?

Using Topamax for weight loss falls under off-label prescribing, a common practice where medications are used for purposes not explicitly approved by regulatory bodies. But is it safe?

Who Might Be Prescribed Topamax for Weight Loss?

Dr. Singh emphasizes that weight loss medications, including off-label use of Topamax, are typically considered for individuals with:

• A Body Mass Index (BMI) of 30 or higher
• A BMI of 27 or higher with weight-related comorbidities

Efficacy of Topamax for Weight Reduction

Research indicates that Topamax can be effective for weight loss:

• Average weight loss: Approximately 11 pounds over 4 months compared to placebo
• Increased likelihood: Users are over six times more likely to achieve significant weight loss
• Duration effect: Longer treatment periods and higher doses tend to yield greater weight loss

Potential Risks and Side Effects of Using Topamax for Weight Loss

While Topamax can be effective for weight management, it’s not without risks. Understanding these potential side effects is crucial for anyone considering its use.

Common Side Effects

Users of Topamax may experience:

• Tingling sensations in extremities
• Cognitive difficulties (e.g., memory problems, difficulty concentrating)
• Changes in taste perception
• Fatigue or drowsiness
• Dizziness
• Nausea

Serious Risks

More severe potential risks include:

• Metabolic acidosis
• Kidney stones
• Glaucoma
• Suicidal thoughts (particularly in individuals with a history of depression)

Certain groups should exercise caution or avoid Topamax altogether:

• Pregnant women (due to increased risk of birth defects)
• Individuals with a history of kidney problems
• Those with glaucoma or other eye conditions
• People with a history of depression or suicidal thoughts

Comparing Topamax to Other Weight Loss Medications

To understand Topamax’s place in weight management, it’s helpful to compare it to FDA-approved weight loss medications.

Topamax vs. FDA-Approved Options

• Efficacy: Topamax’s weight loss effects are generally moderate compared to some FDA-approved options
• Side effect profile: Topamax may have more neurological side effects than some alternatives
• Mechanism: Unlike medications designed specifically for weight loss, Topamax’s effect is a side effect rather than its primary action

FDA-approved weight loss medications include:

• Orlistat (Xenical)
• Liraglutide (Saxenda)
• Phentermine-topiramate (Qsymia) – a combination drug that includes topiramate
• Semaglutide (Wegovy)

Long-Term Considerations: Weight Maintenance After Topamax

An important aspect of using Topamax for weight loss is understanding what happens when treatment stops. Can the weight loss be maintained?

Weight Regain Risk

Studies suggest that discontinuing Topamax often leads to weight regain. This phenomenon is not unique to Topamax and is common with many weight loss interventions. Factors influencing weight regain include:

• Return of appetite suppression effects
• Changes in metabolism
• Behavioral factors

Strategies for Maintaining Weight Loss

To help maintain weight loss after stopping Topamax:

1. Gradually taper off the medication under medical supervision
2. Implement sustainable lifestyle changes (diet and exercise)
3. Consider transitioning to other weight management strategies or medications
4. Regular follow-ups with healthcare providers to monitor weight and overall health

Alternative Approaches to Weight Loss

While Topamax may be an option for some, it’s important to consider other weight loss strategies, especially given its off-label status for this purpose.

Lifestyle Modifications

The foundation of sustainable weight loss often includes:

• Balanced, calorie-controlled diet
• Regular physical activity
• Adequate sleep
• Stress management techniques

Other Medical Interventions

For those requiring medical intervention for weight loss, options include:

• FDA-approved weight loss medications
• Bariatric surgery for severe obesity
• Medically supervised very low-calorie diets

Is Topamax the right choice for weight loss? The answer depends on individual factors, including overall health, weight loss goals, and potential risks. While Topamax has shown efficacy in promoting weight loss, its use for this purpose should be carefully considered and monitored by healthcare professionals. As with any weight loss intervention, the potential benefits must be weighed against the risks, and a comprehensive approach that includes lifestyle modifications remains crucial for long-term success.

Ultimately, the decision to use Topamax for weight loss should be made in consultation with a healthcare provider who can assess individual needs, medical history, and potential alternatives. As research continues, our understanding of Topamax’s role in weight management may evolve, potentially leading to new insights and recommendations for its use in this context.

Topamax for weight loss: Off-label safety and efficacy

Topamax is prescribed to treat epilepsy and migraines, but the drug is also well known for causing weight loss

Is Topamax approved for weight loss? | Dosage | Safety | Risks | Weight gain after Topamax | Other ways to lose weight | FAQs

Topamax is the brand name of a generic medication called topiramate. It’s an anticonvulsant medication that’s used to treat conditions like epilepsy, migraine headaches, and alcohol use disorder. Topamax is great for treating conditions like this, but many people who take it will experience weight loss as a main side effect. Let’s take a more in-depth look at how safe and effective Topamax is, and see how it’s related to weight loss. 

Is Topamax approved for weight loss?

Topamax is approved by the Food and Drug Administration (FDA) to treat epilepsy and migraines, but the drug is also well known for causing weight loss. Even though weight loss may be a positive benefit of taking Topamax, the FDA hasn’t approved it for weight loss alone.  

Topamax causes weight loss because it affects the appetite. People who take it and have a reduced appetite may feel hungry less often and eat less because of this. Studies have shown that Topamax may also speed up metabolism, which means that the body would be digesting food quicker than normal. 

 Clinical trials have shown that about 6%-17% of people who take Topamax will experience weight loss, and while many people may see this as an added benefit, losing too much weight isn’t a good thing. Dr. Kuldeep Singh, a top weight loss surgeon in the Baltimore Metropolitan area and Director of The Maryland Bariatric Center at Mercy Medical Center, says that most people will experience moderate weight loss from Topamax. Losing weight rapidly can be unhealthy, and it may be time to see a doctor if you’re taking Topamax and this happens to you. Maintaining a healthy weight is important, and the best way to find out what target weight is best for you is to ask your doctor. Falling below your target body weight because of Topamax would be another sign that it’s time to talk with your doctor.  

Topamax dosage for weight loss

Because the use of Topamax for weight is off-label and truly a side effect of its use in clinical practice, no specific dose can be specified for this indication. Topamax’s weight loss side effect has resulted in its off-label use to treat binge eating disorders in adults, and the dosing for this indication does not differ greatly in comparison to other approved indications, ranging from 25mg per day to a maximum of 400mg per day. If used off-label for weight loss, the dose will likely begin low at 25mg to 50mg once daily and increase slowly over weeks until a benefit of weight loss is noted – balancing this desirable side effect with those which are less desirable. It is unlikely the dose of topiramate for the indication of weight loss needs to exceed 200 mg per day, as clinical trials have not demonstrated additional benefit in percent body weight lost beyond this dose. An extended-release formulation of topiramate co-formulated with phentermine is available as a product called Qsymia, which is indicated for chronic weight management. The dose of topiramate in this co-formulated product ranges from 23 mg once daily to a maximum of 96 mg once daily. 

Is it safe to take Topamax for weight loss?

Sometimes Topamax can be prescribed off-label to help someone lose weight. Off-label prescribing happens when a doctor writes someone a prescription for a medication that’s approved by the FDA to treat a condition that’s different from what their patient has. This is legal and frequently happens in the medical industry, with an estimated 1 in 5 prescriptions being written off-label. 

A doctor may choose to write someone a prescription for Topamax to help with their weight loss or to treat eating disorders like binging and purging that lead to weight gain. According to Dr. Singh, someone must have a body mass index (BMI) that’s 30 or higher in order to be prescribed any weight loss medication, including Topamax. 

Studies have shown that people who take Topamax for weight loss lose about 11 pounds in comparison to placebo groups if they take the drug for at least four months, and that the weight loss effects of Topamax increase with both duration of treatment and dosage. Studies have also shown that topiramate treatment can increase the chance of statistically significant weight loss by more than sixfold. 

Risks of using Topamax for weight loss

Even though Topamax can be very effective for weight loss, it isn’t safe for everyone. The following groups of people should talk with their doctor before taking Topamax because they may have an increased risk of experiencing serious adverse events if they take it: 

• People with kidney disease
• People with lung disease or breathing problems
• People with liver disease
• People with eye problems such as glaucoma 
• People with depression
• People with suicidal thoughts or behaviors
• People with osteoporosis 
• People with metabolic ketoacidosis 

It may be safe for pregnant women to take Topamax if the benefits of taking the medication outweigh its potential risks. Topamax can cause fetal harm and oral birth defects if it’s taken by pregnant women, which is why it’s prescribed with caution. It’s also excreted in human milk, but it’s unknown whether or not it will negatively impact breastfeeding infants. Topamax can make birth control pills less effective, so it’s important to talk with your doctor about using non-hormonal birth control methods if you don’t want to become pregnant while taking Topamax. 

Side effects of using Topamax for weight loss

People who aren’t pregnant and who don’t have any of the health conditions mentioned above can safely take Topamax, but they may still experience side effects from taking it. Here are some of the most common side effects of Topamax aside from weight loss: 

• Dizziness
• Tiredness
• Numbness
• Diarrhea
• Loss of appetite 
• Loss of coordination
• Paresthesia (burning sensations) 

Although it’s rare, Topamax can cause more serious side effects that may require medical attention like confusion, memory problems, trouble concentrating, and trouble speaking. Some people will also experience mental health side effects like depression, panic attacks, mood changes, and suicidal thoughts or behaviors. If you have any of these symptoms, you should seek medical advice as soon as possible. 

The other rare side effect of Topamax that’s worth mentioning is eye problems that can lead to vision changes and blindness, which is why it’s so important to call your doctor if your vision starts to change. This list of side effects is not comprehensive; if you’d like a complete list of Topamax side effects, you can always ask your doctor or pharmacist for a medication guide. 

If Topamax is causing too many side effects for you, know that you have other options. The active ingredient in Topamax, topiramate, is the main ingredient in the weight loss drug Qsymia, which also contains phentermine. According to Dr. Singh, Qsymia is one of the best medications to use long-term in combination with diet and lifestyle changes for weight loss, especially for obese patients with class 1 or class 2 obesity. So if you’re not able to take Topamax because of an underlying health problem or because you’re experiencing too many adverse effects, you might try asking your doctor about Qsymia or other ways to lose weight. 

How to take Topamax to lose weight

Topamax can be taken to promote weight loss and help control binging and purging, but it’s important to remember that it isn’t a substitute for going to a doctor and creating a well-rounded weight loss plan. If you’re interested in taking Topamax, it’s best to schedule an appointment with your doctor to see if it’s right for you. Your doctor will do a complete physical exam and ask about your medical history. If you and your doctor decide that Topamax can safely help you lose weight, then you may receive a prescription for it.

If you do receive a prescription from your doctor, it’s important to know how to take Topamax to get the best results. The starting dose of Topamax for weight loss is a low dose of 25 mg per day, but this dosage strength can be increased on a case-by-case basis based on each individual’s medical history and how much weight they have to lose.  

In a study done by the Journal of Clinical Psychiatry, bipolar and schizophrenic patients who were given an average dose of 195 mg of topiramate per day lost about 22 pounds over time. This just goes to show that the range of Topamax dosages can vary from low to high and that doctors may increase or decrease the amount of Topamax that someone takes over time-based on the results they are or aren’t getting. 

It can take some time to see weight loss results from taking Topamax. Some people may not notice a difference until they’ve taken the drug for at least four months, while other people may start to lose weight in their first month of taking it. Weight loss results from topiramate are proven to increase over time. 

Topamax can be taken with or without food and is generally taken at the same time each day. It shouldn’t be taken at the same time as certain other medications because of the potential for drug interactions. Here’s a list of medications Topamax shouldn’t be taken with:

• Antiepileptic drugs
• Carbonic anhydrase inhibitors
• CNS depressants
• Oral contraceptives
• Hydrochlorothiazide (HCTZ) 
• Pioglitazone
• Lithium
• Amitriptyline 

In addition to these medications, Topamax shouldn’t be taken with alcohol because this can cause sleepiness, increase the risk of getting kidney stones, and cause metabolic acidosis. Metabolic acidosis is a condition where too much acid builds up in body fluids, and it can become life-threatening if it goes untreated. If you start to experience rapid breathing, confusion, extreme tiredness, and an increased heart rate while taking Topamax, you should seek medical attention as soon as possible because these are signs that you may have metabolic acidosis.

Related: Saxenda for weight loss

Weight gain after Topamax

When someone stops taking Topamax, it’s possible that they might experience some weight gain over time, especially if they haven’t been combining Topamax with healthy lifestyle changes. In an observational study done by the National Library of Medicine, discontinuation of Topamax for at least six months showed a trend for returning to a baseline weight. So people may be more likely to return to what they weighed before they started taking Topamax, but this may take some time. 

This return to a baseline weight may happen because the body is no longer experiencing a reduced appetite and faster metabolism. The best way to make sure you’re able to keep weight off after stopping Topamax is to adopt healthy lifestyle changes that will support you on your weight loss journey. 

5 safe ways to lose weight

Topamax can be helpful on your weight loss journey if your doctor approves it, but it’s not the only way to lose weight. Lifestyle changes can help you lose weight and keep it off so that you can enjoy the benefits of weight loss without taking Topamax, while taking it, or after taking it. Here are some of the safest ways to lose weight. 

1. Improving your eating habits

Eating healthy is one of the safest and best ways to lose weight. Being mindful of what and how much you’re eating can help you lose weight if you do it right. For the best advice on what to eat to lose weight, you should talk with your doctor, but making some small changes like eating more fruits and vegetables can be a great way to start. 

Processed foods, refined carbohydrates, sugar, and alcohol are all examples of foods that can cause weight gain. Fresh fruits, vegetables, and high-quality proteins like salmon, beans, and eggs are all great examples of foods that the body can easily process and get vital nutrients from. 

2. Exercising regularly 

According to the Centers for Disease Control and Prevention (CDC), exercise not only helps control weight, but it reduces high blood pressure, reduces the risk of getting Type 2 diabetes, and can even reduce the symptoms of depression and anxiety. People vary in how much physical exercise they need to lose weight, so it’s a good idea to talk with your doctor about how often you should be exercising. Some great exercises for weight loss include walking, biking, swimming, and weight training. 

3. Reducing stress

Stress is linked to many health problems, such as anxiety and depression, but it’s also been linked to unexpected weight gain. Feeling stressed out can lead to emotional eating, which can lead to weight gain over time. Finding ways to reduce stress may help you lose weight. You might try meditating, yoga, going for walks in a park, or calling a friend or family member. You can also ask your doctor or a counselor for proven ways to reduce stress that might fit into your lifestyle. 

4. Getting enough sleep 

According to the Sleep Foundation, a lack of sleep may increase the appetite and lead to metabolic problems. Getting enough sleep can help your body function properly and give you more energy to do things like exercise, which will help you lose weight. Getting enough sleep can also reduce your stress levels, which will help you control any urges you might get to overeat. 

5. Trying safe diet pills & supplements 

There are countless diet pills and supplements on the market that claim to cause weight loss, such as Hydroxycut and glucomannan, but they shouldn’t serve as a substitute for healthy lifestyle changes. “When people go for weight loss medications, most of them do it because it’s easy to do,” says Dr. Singh. “If somebody seriously changes their lifestyle and eating habits first, they will really see a solid improvement with Topamax or other weight loss medications. The mindset is the most important thing. Medications cannot serve as a substitute for proper eating and exercising habits,” says Dr. Singh. 

Frequently asked questions about Topamax and weight loss

Can Topamax cause rapid weight loss?

Because the weight loss seen with Topamax is related to a decrease in appetite, you won’t begin to see weight loss for a few weeks, if not a couple of months. In addition, the weight loss with Topamax is unlikely to be drastic—most studies have shown a decrease in Body Mass Index (BMI) around the 5-10% mark. 

How much Topamax should I take to lose weight?

For all indications, the Topamax dose is usually started low and increased slowly over time so as to be able to monitor for the onset of unwanted side effects. Clinical studies have shown a plateau of this side effect approaching a dose of 200mg per day, meaning patients exceeding this dose did not demonstrate greater weight loss. 

How long does it take to lose weight on topiramate?

Weight loss by Topamax can be noticed within weeks of starting the medication as it decreases appetite and potentially stimulates metabolism. The additional benefit of Topamax in comparison to other weight loss medications on the market is that there does not seem to be a plateau of weight loss at six months, so the weight loss may be an ongoing effect. 

What is the difference between phentermine and topiramate?

Phentermine is a sympathomimetic medication that is specifically indicated for weight loss. Aside from its FDA-approved indication, due to its mechanism of stimulating the central nervous system, the main difference between the two medications is that phentermine should only be used short-term. 

What is the best weight loss pill?

The best weight loss pill should be individualized to a person since so many weight loss medications are approved to be used to manage additional conditions. Some medications that help manage Type 2 diabetes with a side effect of weight loss make more sense to use in a diabetic patient, whereas topiramate might be best suited for someone that suffers from migraines and needs to lose a little weight. While weight loss might be considered a beneficial side effect, it might not be in all patients; in addition, the other side effects of these medications should be considered in case they won’t jive with a person. Any decision on weight loss medications should be made in conjunction with a healthcare professional with a good understanding of all of a patient’s needs and conditions.

Topamax for Weight Loss: Uses, Dosage, Side Effects

1. Does Topamax work for losing weight?
2. What is Topamax?
3. Topamax uses
4. Topamax side effects
5. Topamax dosage
6. Topamax warnings
7. Topamax interactions 

It may sound strange, but one of the drugs most commonly prescribed for weight loss is not FDA-approved for that purpose. It’s a seizure medication called Topamax (topiramate), that happens to come with a welcome side effect for many people: weight loss. Studies have shown that Topamax can help you lose weight by reducing appetite, so many healthcare providers prescribe it off-label for that purpose. It’s not a magic pill, though. This drug can have several side effects, some of them serious. Find out more below.

Studies have found that about 6–17% of people who take Topamax will lose body weight (National Library, 2021). One review of studies found that people with obesity who took Topamax for at least four months lost an average of about 12 pounds more than the placebo group (Kramer, 2011).

Topamax (topiramate) is FDA-approved to treat seizure disorders (like epilepsy) and migraines. Because one of the side effects is decreasing appetite, some providers prescribe Topamax off-label as a weight loss medication. Other common brand names for this drug are: Qudexy XR, Topiragen, and Trokendi XR. 

Topamax is approved by the FDA for the treatment of (National Library, 2021; FDA, 2012): 

• Epilepsy, a neurological disorder in which brain activity becomes abnormal, causing seizures or other types of unusual behavior
• Migraine headaches, which are recurrent, throbbing headaches that typically affect one side of the head

Topamax can also be used “off-label” to treat other conditions, meaning it wasn’t specifically approved by the FDA for those uses. Drugs can be prescribed by a healthcare provider for an unapproved use if they decide that it’s the right treatment for their patient. 

Off-label uses for Topamax include:

• Weight loss
• Alcohol dependence (MedlinePlus, 2021)

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Common side effects of Topamax include (Fariba, 2021; National Library, 2021):

• Paresthesia (tingling or prickling sensations)
• Altered sense of taste

Topamax can have serious side effects:

• Myopia (nearsightedness) and glaucoma
• Vision defects
• Metabolic acidosis
• High blood ammonia levels
• Trouble with thinking or concentration
• Nausea
• Confusion
• Memory problems
• Trouble speaking
• Depression or mood problems
• Suicidal tendencies
• Tiredness or sleepiness
• Serious skin reactions, including rash or blisters
• Kidney stones
• Low body temperature
• Hair loss

Topamax comes in the following forms (National Library, 2021; Medline Plus, 2021):

• Tablets: 25 mg, 50 mg, 100 mg, and 200 mg
• Sprinkle capsules: 15 mg and 25 mg

Because Topamax hasn’t been approved by the FDA for weight loss, no specific dosage is recommended for that use. Your healthcare provider will recommend a dose based on your health history, physical condition, and other factors.

• Pregnant women shouldn’t take Topamax because it can increase the risk of congenital anomalies (especially cleft lip and cleft palate) in the infant.
• Acute myopia and glaucoma—rare but possible side effects of Topamax—can lead to permanent vision loss.  
• Metabolic acidosis, in which too much acid is produced in the body, can lead to shock or death when severe.
• Antiepileptic drugs, including Topamax, can increase suicidal thoughts or behavior.

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Topamax can interact with the following drugs (National Library, 2021):

• Antiepileptic drugs—Taking phenytoin and carbamazepine with Topamax can decrease blood levels of Topamax. Taking valproic acid with Topamax may cause low body temperature and high levels of ammonia.
• Carbonic anhydrase inhibitors—Topamax is a carbonic anhydrase inhibitor. Taking it with other such medications (like zonisamide and acetazolamide) can increase the risk of metabolic acidosis and kidney stones.
• Central nervous system (CNS) depressants—Topamax alone may cause CNS depression, so it should be used with extreme caution with other CNS depressants, like alcohol.
• Combination oral contraceptives (birth control pills)—Topamax may cause combination oral contraceptives to be less effective.
• Hydrochlorothiazide (HCTZ)—HCTZ is a diuretic (water pill). Taking it together with Topamax can cause concentrations of Topamax to rise, which could be dangerous.
• Lithium—Lithium is used to treat bipolar disorder and other mental illnesses. Taking it together with Topamax can increase the blood levels and effects of lithium.
• Amitriptyline—Amitriptyline is used to combat depression. Taking it together with Topamax can cause a large increase in the concentration of amitriptyline.

If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.

1. Fariba, K. & Saadabadi, A. (2021). Topiramate. [Updated 2021 Aug 6]. In: StatPearls [Internet]. Retrieved on Nov. 3, 2021 from https://www.ncbi.nlm.nih.gov/books/NBK554530/
2. Food and Drug Administration. (2012). Topamax (topiramate) Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020844s041lbl.pdf
3. Kramer, C. K., Leitão, C. B., Pinto, L. C., Canani, L. H., Azevedo, M. J., & Gross, J. L. (2011). Efficacy and safety of topiramate on weight loss: A meta-analysis of randomized controlled trials. Obesity Reviews: An Official Journal of the International Association for the Study of Obesity, 12(5), e338–e347. doi: 10.1111/j.1467-789X.2010.00846.x. Retrieved from https://pubmed.ncbi.nlm.nih.gov/21438989/
4. Medline Plus. (2021). Topiramate. U.S. National Library of Medicine. Retrieved from https://medlineplus.gov/druginfo/meds/a697012.html
5. National Institutes of Health. (2021). TOPAMAX- topiramate capsule, coated pellets. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=21628112-0c47-11df-95b3-498d55d89593
6. U.S. National Library of Medicine. (2021). DailyMed. Label: TOPAMAX- topiramate tablet, coated. TOPAMAX- topiramate capsule, coated pellets. National Institutes of Health. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=21628112-0c47-11df-95b3-498d55d89593

Dr. Steve Silvestro is a board-certified pediatrician and Senior Manager, Medical Content & Education at Ro.

Dosage of Topamax for weight loss – Diet

What is the correct dosage of Topamax for weight loss? The answer is not simple – it depends on a number of factors. When considering the dosage of Topamax for weight loss, one must consider the risks associated with taking the medication versus its benefits.

What is Topamax?

Topamax (drug name topimirate) is a prescription anticonvulsant drug that acts on the frontal cortex of the brain. The main use of Topamax is to combat epilepsy, however there are several off-label uses including migraine prevention, treatment of bipolar disorder and weight loss.

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While scientists aren’t entirely sure how Topamax works, it’s believed that it can actually rewire the part of the brain that controls addiction and also calms excitable nerves, among other things.

How does Topamax promote weight loss?

During clinical trials of Topamax for the treatment of epileptic seizures, many patients in the trial were found to lose weight. This side effect occurs due to several different properties of the drug.

• Patients often find that the taste of food has changed in such a way that it is much less palatable. This is especially noticeable in high-fat foods, sugary foods, and carbonated drinks.
• In many patients, even small doses of Topamax significantly reduce or completely eliminate appetite. Topamax patients often need to be reminded to eat or plan meals so they don’t forget to eat right.
• Topamax appears to act on the addictive centers of the brain, removing addiction stimuli. Because many overweight people are addicted to food, Topamax can eliminate this addictive craving.

Side effects of Topamax

While all of the above may sound like a dream come true for people desperate to lose weight, Topamax is a powerful drug and weight loss can come at a cost. Some side effects of Topamax include:

• Brain fog and loss of mental alertness/intelligence (Topamax is sometimes referred to as “dopamax” due to the prevalence of this side effect).
• Dizziness
• Kidney stones
• Paresthesia (tingling) of the extremities, especially the hands and feet, although it can also occur on the face and other parts of the body.
• Fatigue
• Confusion
• Inability to pay attention
• Coordination problems
• Nausea
• Loss of memory – especially a word access disorder that makes it difficult to find the right word at the right time.
• Dry mouth
• Back pain
• Hair loss

What is the correct dosage of Topamax for weight loss

The dosage of Topamax for weight loss can be from 25mg per day or up to 800mg per day – usually divided into two doses. Due to side effects, most physicians (and drug manufacturers) recommend gradually increasing the dose, starting with a minimum dose of 25 mg and gradually increasing the dose over several weeks. Your doctor will work with you to determine the most effective dose.

Other factors to consider

When choosing Topamax for weight loss, you can take into account the following:

• The use of Topamax for weight loss is not for its intended purpose. Clinical trials to identify Topamax as a weight loss drug were actually completed prematurely as it was determined that the side effects of Topamax were not well tolerated by patients using it for weight loss.
• Many insurers do not cover prescription drugs.
• Patients taking doses greater than 200 mg per day should reduce the dose of the drug if they decide to stop taking it. Abrupt discontinuation of Topamax at doses above this level may cause seizures even in patients who have never had seizures.
• Appetite and food cravings return when Topamax is stopped. It is important to learn proper nutrition and exercise strategies to support weight loss.
• Many patients report weight loss/appetite loss only during the first course of treatment. If you stop taking Topamax and then restart it, the results will not necessarily be the same.
• According to the Topamax package insert, only 16 percent of those who take it lose weight; however, some side effects occur in more than 50 percent of patients.

Conclusion

It is very likely that relatively small doses of Topamax can cause weight loss in many patients. However, it is important to note that the FDA has not approved Topamax for the treatment of weight loss. When considering Topamax, work closely with your doctor and take a close look at the side effects. You may decide that you are better off following a healthy diet and exercise program. .

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Side effect (weight loss) – blondycandy.

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I thought and thought, and decided to tell.
I have already complained about migraines, which I have been suffering from for quite some time. Sometimes they go over the top.
My doctor referred me to a neurologist to help me.
And, as always, I was “lucky” – they prescribed a medicine for the prevention of migraine, which has a side effect – weight loss .
FDA – they are the ones who allow the use of medicines for the population – the use of this drug is officially approved for weight loss.
I, of course, did not know about this, I read it in one of the recent issues Vogue , how the wife of either the vice-president Prada , or someone else, lost weight on this drug.

I’m now slightly hesitant to say the name or not. But in general, it is clear what I will say now.

The doctor suggested me a range of drugs to prevent my migraine.
I was intersted by the side effects. Namely, sleep and weight.
From one drug I lost sleep and stopped eating, as a result I almost went crazy and lost 6 kilos in a month.
It was a wild stimulant.
On the contrary, I got better from another drug, and in order not to become a fat cow, I did insane circuit training five times a week, and also almost went crazy.

As a result of sorting through everything possible, we settled on the drug from Vogue , which is prescribed by “prominent nutritionists in Manhattan.”
This (exhaled and clenched in advance) – Topamax (Topamax). The main action is antiepileptic.
Prescribed off label (that is, in addition to the main action) for the prevention of migraine and weight loss.
At one time, Viagra was also not invented for erection.
Unlike the amphetamine meridia and its Russian counterpart, reduxin, Topamax does not suppress appetite.