How much Benadryl can you safely take. What is the correct dosage for adults and children. Are there risks of taking too much Benadryl. What are the side effects of Benadryl overdose.

Understanding Benadryl: Composition and Uses

Benadryl is a widely used over-the-counter medication containing diphenhydramine as its active ingredient. This antihistamine is primarily used to alleviate symptoms associated with allergies, common cold, and various skin conditions. Available in multiple forms, including tablets, capsules, liquids, and topical applications, Benadryl offers versatile options for symptom relief.

Common uses of Benadryl include:

• Relieving allergic rhinitis (hay fever) symptoms
• Easing common cold symptoms
• Treating itchy or irritated skin
• Managing hives and insect bites
• Addressing eczema discomfort
• Providing relief from sunburn
• Helping with motion sickness
• Aiding in sleep for those with insomnia

Despite its effectiveness, it’s crucial to use Benadryl responsibly and adhere to recommended dosages to avoid potential side effects and complications.

Benadryl Dosage Guidelines: Finding the Right Amount

Determining the appropriate Benadryl dosage depends on various factors, including the condition being treated, age, and the specific form of Benadryl being used. Healthcare professionals generally recommend using the lowest effective dose for the shortest duration possible.

Adult Dosage Recommendations

For adults, the standard oral dosage of Benadryl (diphenhydramine) is typically 25 to 50 mg every 4 to 6 hours. The maximum recommended daily dose should not exceed 300 mg in 24 hours. However, it’s essential to consult with a healthcare provider or pharmacist for personalized dosage advice, especially if you have any underlying health conditions or are taking other medications.

Pediatric Dosage Considerations

Dosing for children requires extra caution. The American Academy of Pediatrics advises against giving diphenhydramine to children under 6 years of age unless specifically directed by a pediatrician. For older children, dosage is typically based on weight rather than age. Always consult a pediatrician before administering Benadryl to children, as there may be safer alternatives available.

Is Benadryl safe for all children? No, Benadryl is not recommended for children under 6 years old without a doctor’s guidance. Alternative antihistamines like loratadine, cetirizine, or fexofenadine are often considered safer options for young children.

The Risks of Exceeding Recommended Benadryl Dosages

While Benadryl is generally safe when used as directed, taking more than the recommended amount can lead to serious side effects and health risks. Overdosing on diphenhydramine can cause a range of symptoms, from mild discomfort to severe medical emergencies.

Potential risks of Benadryl overdose include:

• Extreme drowsiness
• Confusion and disorientation
• Rapid heartbeat
• Blurred vision
• Dry mouth and urinary retention
• Agitation or hallucinations
• Seizures (in severe cases)
• Potential for cardiac arrhythmias

Can Benadryl be habit-forming? While not typically considered addictive, frequent use of Benadryl can lead to tolerance, requiring higher doses for the same effect. This can increase the risk of side effects and potential overdose.

Measuring Benadryl: Ensuring Accurate Dosing

Accurate measurement is crucial when administering Benadryl, especially for liquid formulations. Using the proper measuring tools can help prevent accidental overdosing.

Tips for Accurate Dosing:

1. Use the measuring tool provided with the medication
2. If no tool is provided, ask your pharmacist for an appropriate measuring device
3. Avoid using kitchen teaspoons or tablespoons, as these can be inaccurate
4. For liquid medications, always measure in milliliters (mL) for precision
5. Double-check the concentration of the medication before measuring

Why is precise measurement important? Accurate dosing ensures that you or your child receive the intended amount of medication, maximizing effectiveness while minimizing the risk of side effects or overdose.

Side Effects and Precautions When Using Benadryl

While Benadryl can be effective for many people, it’s important to be aware of potential side effects and take necessary precautions. Common side effects of Benadryl include drowsiness, dizziness, and dry mouth. Some individuals may experience paradoxical effects, such as increased alertness or agitation, particularly in children.

Important Precautions:

• Avoid alcohol consumption while taking Benadryl
• Use caution when operating machinery or driving, as Benadryl can cause drowsiness
• Inform your healthcare provider of all medications you’re taking to avoid potential interactions
• Be cautious if you have certain medical conditions, such as glaucoma, enlarged prostate, or liver disease
• Pregnant or breastfeeding individuals should consult their healthcare provider before using Benadryl

Does Benadryl interact with other medications? Yes, Benadryl can interact with various medications, including other antihistamines, some antidepressants, and certain antipsychotic drugs. Always inform your healthcare provider about all medications you’re taking.

Alternative Antihistamines: Exploring Other Options

While Benadryl is a well-known antihistamine, there are several alternatives that may be more suitable for certain individuals, particularly children or those who experience significant drowsiness with diphenhydramine.

Common Alternatives to Benadryl:

• Loratadine (Claritin)
• Cetirizine (Zyrtec)
• Fexofenadine (Allegra)
• Desloratadine (Clarinex)
• Levocetirizine (Xyzal)

These second-generation antihistamines often cause less drowsiness and may be more suitable for daytime use. However, it’s important to consult with a healthcare provider to determine the most appropriate antihistamine for your specific needs.

Are newer antihistamines more effective than Benadryl? While newer antihistamines may cause less drowsiness, their effectiveness can vary depending on the individual and the specific symptoms being treated. Some people may find Benadryl more effective for certain conditions.

Long-term Use of Benadryl: Considerations and Risks

While Benadryl can be effective for short-term symptom relief, long-term use may pose certain risks and is generally not recommended without medical supervision. Prolonged use of diphenhydramine can lead to tolerance, reduced effectiveness, and potential side effects.

Risks of Long-term Benadryl Use:

• Increased risk of side effects
• Potential for cognitive impairment, especially in older adults
• Possible link to increased risk of dementia with long-term use
• Development of tolerance, requiring higher doses for the same effect
• Masking of underlying conditions that may require different treatment

For chronic allergy symptoms or sleep issues, it’s advisable to consult with a healthcare provider to explore more suitable long-term treatment options.

Can long-term use of Benadryl affect memory? Some studies suggest that long-term use of anticholinergic drugs like Benadryl may be associated with an increased risk of cognitive decline and dementia, particularly in older adults. However, more research is needed to fully understand these potential effects.

Benadryl in Special Populations: Pregnancy, Elderly, and Chronic Conditions

The use of Benadryl requires special consideration in certain populations, including pregnant women, the elderly, and individuals with chronic health conditions. Each group may have unique risks and considerations when it comes to using diphenhydramine.

Pregnancy and Breastfeeding:

Pregnant women should consult their healthcare provider before using Benadryl. While it’s generally considered safe during pregnancy, potential risks should be weighed against the benefits. For breastfeeding mothers, Benadryl can potentially affect milk production and may cause drowsiness in infants.

Elderly Population:

Older adults may be more sensitive to the effects of Benadryl and at higher risk for side effects like confusion, dizziness, and urinary retention. The American Geriatrics Society advises against the routine use of diphenhydramine in older adults due to these risks.

Chronic Health Conditions:

Individuals with certain chronic conditions should use Benadryl with caution:

• Glaucoma: May worsen symptoms
• Enlarged prostate: Can cause urinary retention
• Liver or kidney disease: May affect drug metabolism and clearance
• Heart conditions: Potential for interaction with heart medications

Is Benadryl safe for all elderly individuals? No, Benadryl is generally not recommended for routine use in older adults due to increased risk of side effects and potential for drug interactions. Alternative treatments should be considered when possible.

Emergency Situations: Recognizing and Responding to Benadryl Overdose

While following recommended dosages greatly reduces the risk, it’s crucial to be aware of the signs of Benadryl overdose and know how to respond in such emergencies. Recognizing the symptoms early can be life-saving.

Signs of Benadryl Overdose:

• Severe drowsiness or loss of consciousness
• Confusion and disorientation
• Severely dilated pupils
• Rapid heartbeat or palpitations
• Seizures
• Inability to urinate
• Agitation or hallucinations
• Dry mouth and skin

Emergency Response:

1. Call emergency services immediately if overdose is suspected
2. Provide information about the amount of Benadryl taken and when
3. Follow instructions given by emergency responders
4. Do not induce vomiting unless instructed by medical professionals
5. If the person is unconscious, place them in the recovery position

How quickly do overdose symptoms appear? Symptoms of Benadryl overdose can begin to appear within 20 to 30 minutes after ingestion, but may take longer depending on the amount taken and individual factors.

Proper understanding of Benadryl dosage, its uses, and potential risks is crucial for safe and effective use of this common medication. Always consult with a healthcare provider for personalized advice, especially when considering long-term use or use in special populations. By following recommended guidelines and being aware of potential side effects, you can maximize the benefits of Benadryl while minimizing risks.

Diphenhydramine Dosing Table – HealthyChildren.org

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Safety & Prevention

Safety & Prevention

​Diphenhydramine (also known as Benadryl®) is a medicine used to treat allergic reactions, hives and allergies that affect the nose (called nasal allergies).

It is an “over-the-counter” medicine, meaning that you can get it without a doctor’s prescription. There are other medicines like diphenhydramine that might be safer for young children.

The table* below can help you figure out the right amount of diphenhydramine to give. Use your child’s weight to decide on the right amount. You can find the weight in the top row of the chart.

*Table notes:

• Age of child: Do not give diphenhydramine to children less than 6 years of age unless your child’s doctor tells you to. There are other medicines that are like diphenhydramine but will not make your child sleepy (like loratadine, cetirizine, fexofenadine) that can be bought without a prescription and are safer for young children.
• Measuring the dose for liquid medicines (should be in “mL” or metric units): It is easier to give the right amount of medicine when using a syringe than when using a kitchen teaspoon or tablespoon. Use the tool that comes with the medicine. If a tool does not come with the medicine, ask your pharmacist for one.
• How often to give the medicine (frequency): You can give diphenhydramine every 6 hours as needed.
• Adult dose: 50 mg
• Side effects: This medicine can make a child sleepy. Some children, however, may get more excited and active instead of getting sleepy. Because this medicine can make people sleepy, it is important to be careful when driving or using heavy machines after taking this medicine. This is especially important for teens who are driving.

More information

• How to Use Liquid Medicines for Children
• Using Over-the-Counter Medicines With Your Child
• AAP Allergy Tips
• Create an Allergy and Anaphylaxis Emergency Plan

Last Updated

10/21/2021

Source

American Academy of Pediatrics Council on Quality Improvement and Patient Safety (Copyright © 2021)

The information contained on this Web site should not be used as a substitute for the medical care and advice of your pediatrician. There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances.

How Much Benadryl Can I Take Safely?

Written by
Juhi Modi

Medically reviewed by
HaVy Ngo-Hamilton, Pharm. D.
| May 25, 2022

Benadryl is a common over-the-counter medicine used to relieve symptoms of allergic rhinitis (hay fever) and the common cold, such as runny nose, sneezing, and watery/itchy eyes. It is also used to provide relief from irritated or itchy skin caused by insect bites, hives, eczema, sunburn, and other medical conditions like motion sickness and insomnia. All in all, it has a great variety of uses.

While it is an effective drug, the risk with exemplary over-the-counter medications like Benadryl is that you can easily continue taking it for symptomatic relief without noticing that you are going over the recommended dosage. Doing so can lead to severe side effects. 

This article will discuss the appropriate doses and the risks of taking too much Benadryl.

What is Benadryl?

Brand name Benadryl contains the active ingredient diphenhydramine. It is an over-the-counter antihistamine that helps relieve symptoms of seasonal allergies, the common cold, and itchy skin due to bug bites or allergic reactions. 

Benadryl is available in many different forms, including:

• Oral (to be taken by mouth): tablets, chewable tablets, liquid-filled capsules,liqui-gels, and liquid solution
• Topical (to be applied to the skin): creams, gels, and sprays

Some combination products contain diphenhydramine as the main ingredient along with other ingredients. For example, Benadryl Allergy Plus Congestion for Sinus Pressure & Nasal Congestion Relief contains diphenhydramine, an antihistamine, and phenylephrine, a nasal decongestant.

What is the correct Benadryl dosage?

The correct Benadryl dosage depends on several factors. Among those factors is the condition you’re treating, your age, and the form of Benadryl you’re using. Your physician will advise you to take the lowest effective dose of Benadryl for the shortest possible time as best practice recommends.

Regarding effective Benadryl dosing, commonly used and recommended doses of Benadryl are as follows:

For hay fever, allergies, and common cold symptoms

The recommended dose for adults and children 12 years and older is 25 mg to 50 mg every 4 to 6 hours. 

The recommended dose for children between the ages of 6-12 is 12.5 mg to 25 mg every 4 to 6 hours. 

Children under the age of 6 e should not take oral Benadryl without a doctor’s prescription. 

For itchy skin from insect bites, stings, hives, allergic reactions, or other causes

Adults and children from age 2+ can use the topical form of Benadryl and apply gel, cream, or spray to the affected area up to 4 times daily unless the area is widespread and the oral form is advised by a healthcare professional. Children under 2 years of age should use Benadryl topical products only if advised by a physician.

This is a general dosing guide. Some patients, for example, elderly patients, may need to take lower doses of this medication. If you have any specific questions about Benadryl dosages regarding your age and condition, you should consult your doctor or pharmacist. 

What is the maximum dosage of Benadryl?

The maximum dose of Benadryl for adults and children over 12 years of age is 300 mg per day. The maximum dose of Benadryl for children between the ages of  6 to 12 is 150 mg per day. Do not take more than 6 doses of oral Benadryl in 24 hours. 

Benadryl topical products (creams, gels, sprays) should not be applied to the skin more than 4 times a day.

It is important to check all your other antihistamines and ensure that your other medications don’t contain the same active ingredient, i.e., diphenhydramine. The maximum dose mentioned above is the dose you can safely take from all products and different forms combined.

What are Benadryl’s side effects?

The common side effects of Benadryl include sleepiness, dizziness, headache, dry mouth, dry eyes, and weakness. If these symptoms are severe or do not go away after a few days, talk to your doctor or pharmacist.

Benadryl can also cause more serious side effects, such as problems with cognition (thinking),  memory, fast heartbeat (tachycardia), and seizures. Contact your doctor if you experience these side effects and seek emergency medical care for serious side effects such as seizures. 

What are Benadryl risks and drug interactions?

Benadryl can cause drowsiness, which can impair your ability to drive, operate heavy machinery, or do anything that requires focus. Falling asleep at the wheel can result in accidents, so follow your doctor’s instructions and do not drive while taking Benadryl until you know how this medication affects you.

If you are taking other drugs, talk to a healthcare provider before taking Benadryl to avoid serious drug interactions. For example, taking Benadryl with benzodiazepines (Valium, Xanax, Klonopin) can increase the risk of confusion, drowsiness, and delirium. Mixing Benadryl and alcohol can lead to drowsiness and sedation, increasing the risk of accidents and injuries.

How many days in a row can you take Benadryl?

You should not use over-the-counter (OTC) Benadryl for longer than 7 days as treatment for cold and allergy symptoms. OTC Benadryl is intended for short-term use to provide temporary relief of allergy symptoms. If your symptoms do not improve after a week of Benadryl use, contact your doctor to obtain an accurate diagnosis and discuss alternative treatments.

What happens if you take too much Benadryl?

Scientists do not know a lot about the side effects of taking Benadryl long-term, but it has been linked to conditions such as:

• Constipation
• Weight gain
• Blurred vision
• Hallucinations 
• Memory problems, confusion, dementia
• Restless legs syndrome
• Depression and anxiety
• Tolerance and dependence

Can you overdose on Benadryl?

Yes, you can overdose on Benadryl. Signs and symptoms of a Benadryl overdose may include:

• Confusion
• Blurred vision
• Dry mouth
• Dizziness
• Heart arrhythmia
• Difficulty breathing
• Irritability
• Restlessness
• Confusion
• Hallucinations
• Shock
• Seizures
• Coma
• Death

If you or someone you know may have overdosed on Benadryl, call 911 or seek care at the nearest emergency room without delay.

Wrapping Up: Safe use of over the counter medications like Benadryl

It is not safe to take more than the recommended dosage of over-the-counter medicines like Benadryl. Taking too much Benadryl can cause serious problems, including hallucinations, abnormal heart rhythms, seizures, and even death. Always read the labels on OTC medications carefully and ensure that you take the recommended daily dosage. 

References:

1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=702f9786-7ce9-43e4-921d-e1db09612127
2. https://medlineplus. gov/druginfo/meds/a682539.html#
3. https://www.benadryl.com/benadryl-dosing-guide

Benadryl Dosages, Forms and Benefits | SingleCare – Product Information

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Benadryl forms and strengths | Benadryl for adults | Benadryl for children | Dosage table of Benadryl | Dosage of Benadryl for Allergies | Dosage of Benadryl for motion sickness | Dosage of Benadryl for insomnia | Benadryl for pets | How to take Benadryl | FAQs

Benadryl is an over-the-counter medication that temporarily relieves allergy symptoms caused by a natural substance in the body called histamine. Diphenhydramine, the active ingredient in the branded drug Benadryl, is an antihistamine that blocks the activity of histamine and reduces symptoms such as runny nose, watery eyes, and itching.

Diphenhydramine also causes drowsiness and slows down the part of the brain that controls nausea. For these reasons, Benadryl may also be used to relieve occasional insomnia or prevent motion sickness.

For patients over 12 years of age, the standard dosage of Benadryl Allergy is 25 to 50 mg (milligrams) – one to two tablets or capsules – every four to six hours. Children aged 6 to 11 years can be given Benadryl at a maximum dose of 25 mg (one tablet or capsule) every four to six hours. Benadryl can be taken with or without food.

RELATED: What is a Benadryl Allergy? | Benadryl Allergy Coupons

Benadryl Formulations and Strengths

Benadryl tablets and softgels contain 25mg of diphenhydramine hydrochloride and are usually taken by adults and children 6 years of age and older. Benadryl Allergy Plus, however, also contains 10 mg of phenylephrine hydrochloride, a nasal decongestant. Benadryl Allergy Plus Congestion should not be given to children under 12 years of age unless directed by a doctor.

• Benadryl Allergy Ultratab : 25 mg diphenhydramine per tablet
• Benadryl Allergy Liquid Gels without dyes : 25 mg diphenhydramine per gel capsule
• Ben adryl Allergy Plus Congestion : 25 mg diphenhydramine / 10 mg phenylephrine per tablet

Benadryl Adult Dosage

The standard adult dose of Benadryl is one to two tablets or softgels (25-50mg) every four to six hours.

• Standard Adult Dose of Benadryl: One to two tablets/capsules (25-50mg) every four to six hours.
• Maximum adult dosage of Benadryl: Two tablets/capsules (50 mg) every four hours, maximum 12 tablets (300 mg) in 24 hours.

Benadryl dosage for children

Benadryl dosages may depend on the age or weight of the children. Children’s allergy to Benadryl is more suitable for children aged 6 to 11 years. Contains half the dose of diphenhydramine (12.5mg) as Benadryl Allergy, Children’s Benadryl Allergy, sold in a child-friendly liquid and chewable tablet form.

• Children’s dosage of Benadryl for children 2 to 5 years of age: Do not give unless directed by a physician.
• Benadryl dosage for children 6 to 11 years old: One to two chewable tablets or 5 to 10 ml every four to six hours, maximum 12 tablets or 60 ml in 24 hours.
• Pediatric dosage of Benadryl for children 12 years of age and older: Two to four chewable tablets or 10 to 20 ml every four to six hours, maximum 24 tablets or 120 ml in 24 hours.

RELATED: What is Children’s Benadryl? | Benadryl coupons for children

Benadryl (adult drug) can be given to children between 6 and 11 years of age, but should not be given to children under 6 years of age. Although Benadryl Allergy can be used to relieve insomnia. in children 12 years of age and older, it should not be used as a sleeping pill in children under 12 years of age.

• Standard dose of Benadryl for children under 6 years: Do not give unless directed by a doctor.
• Standard dose of Benadryl for children 6 to 11 years old: One tablet/capsule (25 mg) every four to six hours.
• Maximum dosage of Benadryl for children aged 6 to 11 years: One tablet/capsule (25 mg) every four hours, maximum six tablets (150 mg) in 24 hours.

Children aged 6 to 11 should not be given Benadryl Allergy Plus Congestion except under the direction of a pediatrician.

901 25 Not prescribed without a doctor’s order.

Benadryl dosage for allergy symptoms

Benadryl relieves symptoms caused by allergies, hay fever, or the common cold, including runny nose, nasal congestion, sinus pressure, sneezing, rash, watery or itchy eyes, and itchy nose. It is also indicated for the relief of pruritus (pruritus) caused by the release of histamine due to an allergic reaction (contact dermatitis), urticaria (urticaria), or insect bites.

• Adults and adolescents (12 years of age and older): 25–50 mg every four to six hours.
• Pediatric patients (6-11 years): 25 mg every four to six hours.
• Patients with renal insufficiency:
  • Creatinine clearance 10-30 ml/min: No adjustment.
  • Dialysis: no adjustment and no additives.
• Other warnings: Talk to your doctor before taking Benadryl if you have any of the following:
  • Ocular hypertension or glaucoma
  • Hyperthyroidism
  • Cardiovascular disease
  • High blood pressure
  • Asthma or COPD
  • Gastrointestinal obstruction or peptic ulcer 900 38
  • Enlarged prostate
  • Bladder neck obstruction

Benadryl dosage for motion sickness

Benadryl can be used to prevent and treat motion sickness.

• Adults and adolescents (12 years of age and older): 25 to 50 mg 30 minutes before travel and every six to eight hours while traveling.
• Pediatric patients (6-11 years old): 12.5 to 25 mg 30 minutes before travel and every six to eight hours during travel.

Benadryl Dosage for Insomnia

Benadryl may be used for the occasional relief of insomnia or travel-related insomnia in adults and adolescents 12 years of age and older.

• Adults and adolescents (12 years of age and older): 25 to 50 mg 30 minutes before bedtime.
• Pediatric patients (6-11 years): Do not give unless directed by a physician.

Benadryl Dosage for Pets

Benadryl is not approved for use in pets, but veterinarians prescribe diphenhydramine in dogs, cats, and large animals to treat allergic reactions, nose allergies, itching, hives, motion sickness, and anxiety problems. Veterinarians also use diphenhydramine to treat certain types of cancer (mast cell tumors), shock, life-threatening allergic reactions, and other conditions.

The standard veterinary dosage is 2 to 4 mg diphenhydramine per kilogram of body weight (1 to 2 mg per pound) two or three times a day. However, check with your veterinarian before giving your pet Benadryl or any other over-the-counter medication.

RELATED: How to treat allergies in cats and dogs six o’clock or doctor’s instructions. Benadryl can be taken with or without food.

• Follow the instructions on the medicine label if you are taking this medicine without a prescription.
• If you are taking this medicine with a prescription, your doctor will tell you how much to use. Do not use more than indicated.
• Swallow the tablet or softgel whole. Do not crush, break or chew it.

Safety Tips

When taking or using Benadryl, you can consider the following safety and efficacy tips:

• Always check the expiration date. If the medicine has expired, dispose of it safely and buy a new box.
• Benadryl should be stored at room temperature (68°C -77F)
• Check all other medicines you or your child are taking to make sure they also do not contain diphenhydramine or phenylephrine. Both are commonly found in combination with cold, flu, or allergy medications. Pay special attention to topical itch medications that may contain diphenhydramine. These drugs, including topical diphenhydramine, should never be used with Benadryl.
• Do not take Benadryl with alcohol or sedatives.
• People who have glaucoma, breathing problems due to emphysema or chronic bronchitis, or difficulty urinating due to an enlarged prostate should talk to a doctor before taking Benadryl.
• Pregnant or breastfeeding women should consult their physician before taking Benadryl.
• Although Benadryl is approved for use in children 6 years of age and older, Benadryl Allergy should not be used as a sleep aid in children under 12 years of age.
• For motion sickness, take Benadryl 30 minutes before travel or movement. If you are going on a long trip, take the following doses every six to eight hours.
• Record the time for each dose in a diary or schedule so that the next dose is not given too soon.
• Benadryl is a sedative, so do not operate machinery or drive if you feel tired, drowsy or lose concentration. Before taking diphenhydramine, it is recommended to remove obstacles and dangers in the house.

Benadryl Dosage FAQ

How long does Benadryl last?

When taken as directed, Benadryl Allergy usually starts working 30 minutes after ingestion and reaches peak levels in the body in about two hours. In general, food does not affect the absorption of Benadryl and does not reduce its effectiveness. However, regular use of Benadryl can lead to tolerance. Over time, the standard dose may gradually lose effectiveness.

How long does Benadryl stay in your body?

At the recommended dosage, the effects of Benadryl should last between four and six hours, but this may vary. Generally, the amount of time Benadryl stays in the system increases with age.

Health care providers measure how long a drug stays in the body by its half-life, which is the time it takes for the body to eliminate half the amount of the drug in the body. The half-life of diphenhydramine in children is four to seven hours (average five hours). For adults, the elimination half-life is seven to 12 hours (mean nine hours). For the elderly, the elimination half-life is nine to 18 hours (mean: 13.5 hours).

What happens if I miss a dose of Benadryl?

No problem if you don’t take a dose of Benadryl. Take the missed dose at any time. The dosing schedule will be reset, so wait at least four hours before taking your next dose. Do not take extra medicine to make up for a missed dose.

How can I stop taking Benadryl?

You can safely use Benadryl regularly to treat allergic reactions, insomnia, or motion sickness. It should only be used occasionally as a sleep aid. Diphenhydramine – This is sometimes abused. Chronic use of Benadryl, especially to relieve anxiety or insomnia, can lead to addiction and withdrawal symptoms if Benadryl is stopped quickly. High doses of Benadryl can cause severe heart problems, seizures, coma and death. Before you stop taking Benadryl, talk to your doctor about lowering your Benadryl dose or using alternative medications or treatments to reduce anxiety or treat insomnia.

You should stop taking Benadryl and consult your doctor if you experience excessive nervousness, drowsiness, allergic reactions, or if symptoms do not improve after seven days.

What can be used instead of Benadryl Allergy?

Health care professionals generally do not recommend the use of first-generation antihistamines such as diphenhydramine, the active ingredient in Benadryl. Second-generation antihistamines are as effective as diphenhydramine but do not cause as much sedation or drowsiness. Instead of Benadryl Allergy, you can choose several second-generation OTC antihistamines such as Claritin (loratadine), Alavert (loratadine), Allegra (fexofenadine), Zyrtec (cetirizine), and Xyzal (levocetirizine).

What is the maximum dosage of Benadryl?

The maximum dose is 50 mg (two tablets or softgels) every four hours to a maximum of 300mg (12 tablets or softgels) in any 24 hour period for adults and adolescents 12 years of age and older.

For children aged 6 to 11 years, the maximum dose is 25 mg (one tablet or softgel) every four hours, but not to exceed 150 mg (six tablets or capsules) in any 24 hour period.

What interacts with Benadryl?

Food does not affect the absorption or effectiveness of Benadryl.

Some over-the-counter and prescription drugs may interact with Benadryl, and some may reduce the effectiveness of Benadryl. Medicines that depress or slow down the central nervous system, such as tranquilizers, alcohol, or sedatives, may increase the side effects of Benadryl, such as drowsiness, dizziness, sedation, dry mouth, and blurred vision. Always check with your doctor before taking Benadryl Allergy with central nervous system depressants or other medicines.

Benadryl Allergy Plus Congestion also contains phenylephrine, a stimulant. When taken with monoamine oxidase inhibitors (MAOIs), a family of medications that includes certain types of antidepressants, antibiotics, and drugs for Parkinson’s disease, phenylephrine can cause dangerous and potentially life-threatening increases in blood pressure. Do not take Benadryl with an MAOI or within 14 days of stopping an MAOI inhibitor. Check with your doctor, pharmacist, or other health care provider if you think a medicine you are taking may be an MAO inhibitor.

Resources:

• Benadryl Allergy, Epocrates
• Children’s Benadryl, Epocrates
• Dosing Guide, Johnson & Johnson
• Benadryl Allergy Ultratab Tablets, Johnson & Johnson 900 38
• Dye-Free Benadryl Allergy Liquid Gels, Johnson & Johnson
• Benadryl Allergy Plus Congestion, Johnson & Johnson
• Compound Summary, National Library of Medicine
• Diphenhydramine, StatPearls
• Diphenhydramine for Animals , VCA Hospitals
• Chronic Diphenhydramine Abuse and Withdrawal Syndrome , Neurology: Clinical Practice
• Antihistamine Doses , MSD Veterinary Manual
• Far macological treatment of motion sickness, LOUSE. Pharmacist
• FDA warns of serious problems with high doses of allergy drug diphenhydramine. , FDA

Benadryl (Diphenhydramine): Uses, Dosage, Side Effects, Interactions, Warning

Benadryl

• Generic Name: Diphenhydramine
• Brand Name: Benadryl

• Product Description
• Indications and Dosage warnings and precautions
• Overdose and contraindications
• Clinical pharmacology
• Medication guide

Product description

What is Benadryl and how is it used?

Benadryl is a prescription medicine used to treat the symptoms of allergic reactions, insomnia, and motion sickness. Benadryl can be used alone or with other medicines.

Benadryl belongs to a class of drugs called 1st generation antihistamines, antiemetics.

Benadryl is not known to be safe and effective in children under 2 years of age.

What are the possible side effects of Benadryl?

Benadryl can cause serious side effects, including:

• rapid heartbeat or fluttering in the chest,
• painful or difficult urination,
• little or no urination,
• confusion ,
• frivolity ,
• tightness in the neck or jaw, and
• uncontrollable movements of your tongue

Get medical help right away if you have any of the above symptoms.

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The most common side effects of Benadryl include:

• dizziness,
• drowsiness,
• loss of coordination,
• dry mouth, nose or throat,
• constipation,
• upset stomach,
• dry eyes,
• blurred vision, and
• daytime sleepiness or hangover

Tell your doctor if you have any side effects that bother you or that don’t go away.

These are not all possible side effects of Benadryl. For more information, contact your doctor or pharmacist.

Ask your doctor about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

DESCRIPTION

Benadryl Allergy contains the histamine blocker diphenhydramine. This product relieves: runny nose; sneezing itchy, watery eyes; itching in the throat.

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Ingredient

Inactive Ingredients

candelilla wax, colloidal silicon dioxide, crospovidone, hypromellose, microcrystalline cellulose, polyethylene glycol, providone, pregelatinized starch, starch, stearic acid, titanium dioxide and talc in a day. Use as directed.

Indications and dosages

INDICATIONS

Benadryl Allergy (diphenhydramine)

• temporarily relieves these symptoms caused by hay fever or other upper respiratory allergies:
  • runny nose
  • sneezing
  • itchy, watery eyes
  • itchy nose or throat
• relieves these symptoms temporarily due to a cold:
  • runny nose
  • sneeze

DOSAGE AND ADMINISTRATION

Directions

• do not use more than directed (see OVERDOSE warning)0128 25 to 50 mg (1 to 2 capsules). children 6 to 12 years old 12.5 mg ** to 25 mg (1 capsule). children under 6 years consult physician

  ** 12.5 mg dosage not available in Benadryl (diphenhydramine) Allergy Kapseals.

  Other information

  • store between 59° and 77° F in a dry place.
  • protect from light

  HOW SUPPLIED

  Available in:
  Ultratabs: Box of 24, 48 and 100 tablets
  Capsule Capsule: Box of 24 and 48

  FDA Revision Date: 07/01/1997

  Adverse effects and drug interactions

  SIDE EFFECTS

  When using this product:

  • marked drowsiness may occur
  • avoid alcoholic beverages
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • irritability may occur, especially in children
  • be careful when driving or operating machinery

  DRUG INTERACTIONS

  Consult your doctor or pharmacist before use if you are taking sedatives or tranquilizers.

  Warnings and Precautions

  WARNINGS

  Alcohol Warning : If you drink 3 or more alcoholic drinks every day, ask your doctor if you should take paracetamol or other pain/fever medications. Acetaminophen can cause liver damage.

  PRECAUTIONS

  No information provided.

  Overdose and contraindications

  OVERDOSAGE

  Overdose warning : Taking more than the recommended dose may cause liver damage. In case of overdose, seek medical attention or contact a Poison Control Center immediately. Prompt medical attention is important for both adults and children, even if you don’t notice any signs or symptoms.

  CONTRAINDICATIONS

  No information provided.

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  Clinical pharmacology

  CLINICAL PHARMACOLOGY

  No information provided.

  Medication Guide

  PATIENT INFORMATION

  Do not use

  • with another product containing any of these active ingredients
  • if you are currently taking a prescription monoamine oxidase (MA) inhibitor OI) (certain drugs used to treat depression, mental or emotional states or Parkinson’s disease), or within 2 weeks after stopping the MAOI drug. If you are unsure if your prescription drug contains an MAOI, check with your doctor or pharmacist before taking this product.
  • with any other product containing diphenhydramine, even if used on the skin.

  Consult a physician before use if you have heart disease

• glaucoma
• thyroid disease
• diabetes urinary problems due to enlarged prostate
• high blood pressure
• problems with breathing, such as emphysema or chronic bronchitis
• cough with excessive phlegm (mucus)
• persistent or chronic cough, such as from smoking, asthma or emphysema

Consult your doctor or pharmacist before use if you are taking sedatives or tranquilizers.

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When using this product

do not use more than indicated

• marked drowsiness may occur
• avoid alcoholic beverages
• alcohol, sedatives and tranquilizers may increase drowsiness
• be careful when driving or operating machinery children

Stop using and see a doctor if

• redness or swelling
• severe sore throat
• You are nervous, experiencing dizziness or insomnia
• new symptoms appear
• fever intensify or lasts more than 3 days
• Pain, cough or nose, the accumulation worsens or lasts more than 5 days (children) or 7 days (adults)
• pain in the pain in sore throat lasts more than 2 days, accompanied by or followed by fever, headache, rash, swelling, nausea or vomiting
• cough comes back or occurs with persistent rash or headache.