How do ibuprofen and acetaminophen differ in their effects. What is the recommended dosage for each medication. Is it safe to take ibuprofen and acetaminophen together. What are the potential side effects and interactions of combining these pain relievers.

Understanding Ibuprofen and Acetaminophen: Key Differences and Uses

Ibuprofen and acetaminophen are two of the most commonly used over-the-counter (OTC) pain relievers. While both are effective at treating pain and reducing fever, they work in different ways in the body:

• Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and has antiplatelet effects
• Acetaminophen, also known as Tylenol, is processed by the liver and primarily relieves pain and fever without significant anti-inflammatory action

Both medications can help with everyday aches and pains like headaches, muscle soreness, menstrual cramps, and minor injuries. However, ibuprofen may be more effective for conditions involving inflammation like arthritis or sprains.

Proper Dosage and Timing for Ibuprofen

When taking ibuprofen, it’s crucial to follow proper dosage guidelines:

• Adults can take 200-400 mg every 4-6 hours
• Maximum OTC daily dose is 1200 mg (6 tablets of 200 mg)
• Prescription doses may allow up to 3200 mg daily
• Always take the lowest effective dose

How long does ibuprofen stay in your system? The effects typically last 4-6 hours, which is why dosing is recommended at those intervals. However, ibuprofen can be detected in urine for up to 24 hours after the last dose.

Acetaminophen Dosage Guidelines and Precautions

Acetaminophen dosage recommendations differ slightly from ibuprofen:

• Adults can take 325-650 mg every 4-6 hours
• Maximum daily dose is 3000-4000 mg, depending on the product
• Extended-release formulations allow for less frequent dosing

Why is it important to be cautious with acetaminophen dosage? Exceeding the recommended dose can lead to severe liver damage. Always check product labels carefully, as acetaminophen is found in many combination cold and flu medications.

Combining Ibuprofen and Acetaminophen: Benefits and Risks

Taking ibuprofen and acetaminophen together can provide enhanced pain relief for some conditions. This combination is often recommended for post-surgical pain or severe headaches. However, it’s essential to understand the potential risks and proper usage:

• Stagger doses by taking ibuprofen and acetaminophen at different times
• Never exceed the maximum recommended dose for either medication
• Consult a healthcare provider before regularly combining these medications

Is there an increased risk of side effects when combining ibuprofen and acetaminophen? While the combination is generally considered safe when used as directed, it may increase the risk of gastrointestinal issues or liver problems in some individuals. Always monitor for any unusual symptoms and discontinue use if problems arise.

Potential Side Effects and Precautions for Ibuprofen Use

While ibuprofen is generally safe for most people when used as directed, it can cause side effects, especially with long-term or high-dose use:

• Stomach upset, ulcers, or bleeding
• Increased risk of heart attack or stroke
• Kidney problems, especially in older adults or those with existing kidney issues
• Allergic reactions in some individuals

Who should avoid or use caution with ibuprofen? Pregnant women, especially in the third trimester, should avoid ibuprofen. People with a history of stomach ulcers, heart problems, or kidney disease should consult their doctor before using ibuprofen regularly.

Acetaminophen Safety Concerns and Contraindications

Acetaminophen is often considered safer than NSAIDs for many people, but it still carries risks:

• Liver damage from overdose or long-term high-dose use
• Rare but serious skin reactions
• Potential interactions with alcohol consumption

How can you minimize the risks associated with acetaminophen use? Always follow dosage instructions carefully, avoid alcohol when taking acetaminophen, and be aware of other medications that may contain acetaminophen to prevent accidental overdose.

Choosing Between Ibuprofen and Acetaminophen: Factors to Consider

When deciding which pain reliever to use, consider the following factors:

• Type of pain or condition (inflammatory vs. non-inflammatory)
• Individual health factors and medical history
• Potential side effects and risks
• Other medications being taken

When might ibuprofen be a better choice than acetaminophen? For conditions involving inflammation, such as arthritis or sprains, ibuprofen may provide more effective relief. However, for those with stomach sensitivities or a history of ulcers, acetaminophen might be a safer option.

Specific Conditions and Recommended Pain Relievers

Different types of pain may respond better to specific medications:

• Headaches: Both can be effective, but some people find better relief with one over the other
• Menstrual cramps: Ibuprofen often works better due to its anti-inflammatory properties
• Fever: Both are effective, but acetaminophen is often preferred for children
• Toothache: Ibuprofen may provide better relief due to its anti-inflammatory action

Interactions with Other Medications and Substances

Both ibuprofen and acetaminophen can interact with other medications and substances:

Ibuprofen Interactions

• Blood thinners like warfarin
• Some antidepressants
• ACE inhibitors and diuretics used for blood pressure
• Alcohol (increased risk of stomach bleeding)

Acetaminophen Interactions

• Certain antibiotics
• Some seizure medications
• Alcohol (increased risk of liver damage)

Why is it important to inform your healthcare provider about all medications and supplements you’re taking? This information helps prevent potentially dangerous drug interactions and ensures you’re using pain relievers safely and effectively.

Long-Term Use Considerations for Ibuprofen and Acetaminophen

While these medications are safe for occasional use, long-term or chronic use can lead to complications:

Ibuprofen Long-Term Risks

• Increased risk of cardiovascular events
• Gastrointestinal bleeding or ulcers
• Kidney function decline

Acetaminophen Long-Term Risks

• Liver damage or failure
• Potential kidney issues

How can you minimize risks associated with long-term pain reliever use? If you find yourself needing pain relief regularly for more than a few weeks, consult with a healthcare provider to explore underlying causes and alternative treatment options.

Alternative Pain Relief Methods and When to Seek Medical Advice

While OTC pain relievers are convenient, they’re not always the best solution for every situation. Consider these alternatives and know when to seek professional help:

Non-Medication Pain Relief Options

• Physical therapy or exercise
• Hot or cold therapy
• Massage or acupuncture
• Stress reduction techniques like meditation

When to Consult a Healthcare Provider

• Pain persists for more than a few days
• Pain is severe or worsening
• You’re taking pain relievers regularly for extended periods
• You experience unusual side effects

What are some signs that your pain might indicate a more serious condition? Severe, persistent, or worsening pain, especially when accompanied by other symptoms like fever, weakness, or changes in bodily functions, should prompt a medical evaluation.

Understanding the proper use, benefits, and risks of common pain relievers like ibuprofen and acetaminophen is crucial for managing everyday aches and pains safely. By following dosage guidelines, being aware of potential interactions and side effects, and knowing when to seek medical advice, you can effectively use these medications while minimizing risks. Remember, while OTC pain relievers are readily available, they are still potent medications that require careful consideration and responsible use.

How much ibuprofen can I take and how often?

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 6, 2022.

What is the maximum amount you can take?

Adults can take one or two ibuprofen 200mg tablets (200mg to 400mg) three or four times daily if they need to. You should only take ibuprofen every 4 to 6 hours.

You should not take more than 6 tablets (1200mg) in total in one day if you have bought them over the counter, from a supermarket or drug store. You should always try and take the smallest dose needed that gives you relief.

If your doctor has prescribed them for you on prescription, usually as a higher strength tablet, then you can take a maximum of 3200mg in one day.

How much ibuprofen is in a single dose?

A single dose of ibuprofen contains 200mg if it has been bought over the counter from a supermarket or a drug store. Extra strength tablets usually contain 400mg. Some prescription strengths of ibuprofen contain an even higher dose, such as 600mg or 800mg. Always check the label on the packet to make sure you know what dosage your ibuprofen tablets contain.

How often can you take Ibuprofen?

You can take ibuprofen every four to six hours.

How much ibuprofen can you take in a day?

You should not take more than 6 tablets (1200mg) in total in one day if you have bought them over the counter, from a supermarket or drug store.

If your doctor has prescribed them for you on prescription, usually as a higher strength tablet, then you can take a maximum of 3200mg in one day.

You should always try and take the smallest dose needed that gives you relief.

How much ibuprofen is too much?

More than 3200mg of ibuprofen in one day is too much.

What happens if you take too much ibuprofen?

If you take too much ibuprofen you may develop stomach problems, such as heartburn, indigestion, or a stomach ulcer. You may experience bleeding from your gastrointestinal tract or from anywhere in your body and you may feel dizzy.

Occasionally people who have overdosed on ibuprofen have developed kidney failure or seizures. Metabolic acidosis (a build-up of acidic by-products in the blood) has been reported and an increase in the time it takes for blood to clot can occur.

If you suspect a person has overdosed on ibuprofen, seek medical attention immediately. Usually, doctors can reverse the effects of an ibuprofen overdose if the person is seen quickly.

References

• Ibuprofen. Updated 01/2021. Drugs.com https://www.drugs.com/ibuprofen.html
• Ibuprofen (oral route). Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/proper-use/drg-20070602

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Drug information

• Ibuprofen Information for Consumers
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  (for Health Professionals)
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  (detailed)

Related support groups

• Ibuprofen
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Medical Disclaimer

Is it safe to take ibuprofen and Tylenol together?

Ibuprofen and acetaminophen | Dosage | Side effects | Interactions | Which is safer | Mixing OTC pain relievers | Overdose

Over-the-counter (OTC) pain relievers are a great option to treat everyday aches and pains. They are widely available and help remedy mild to moderate pain from a variety of conditions: sore throats, menstrual cramps, toothaches, sprains, muscle aches, abdominal pain, minor aches, headaches, arthritis pain, and most acute pain. Some of the most popular pain medications are ibuprofen and acetaminophen.

You might know acetaminophen by its brand name, Tylenol. Ibuprofen is also a generic pain reliever branded as Advil and Motrin. 

“Acetaminophen is a medication that is usually metabolized by the liver,” says Sasan Massachi, MD, a primary care physician in Beverly Hills, California. “Ibuprofen is an NSAID (nonsteroidal anti-inflammatory drugs) that causes inhibition in a specific enzyme within the body.”

 Both acetaminophen and ibuprofen reduce fevers and pain effectively. However, ibuprofen also reduces inflammation and has antiplatelet effects. As an antiplatelet, ibuprofen reduces blood clots and may increase the risk of bleeding.

RELATED: Acetaminophen details | Ibuprofen details

Can you take Tylenol and ibuprofen together?

It is safe to use acetaminophen and ibuprofen together in the recommended amount. A 2019 Cochrane Review found ibuprofen plus paracetamol (another name for acetaminophen) provided better pain relief than either drug alone and reduced the chance of needing additional pain relievers over approximately eight hours. 

Although it is safe to use these pain relievers together, Dr. Massachi only recommends taking acetaminophen and ibuprofen simultaneously in rare cases. “Sometimes we have patients alternate by taking ibuprofen or Tylenol specifically as a fever reducer, so we are able to get the benefits of both medications without the risk of side effects,” he says.

How much ibuprofen and acetaminophen can I take together?

Ibuprofen and acetaminophen can be safely used together, but they should always be used at the lowest possible doses to achieve relief and the recommended daily dose should not be exceeded.

“The usual safe doses for ibuprofen is up to [a maximum of] 800 milligrams (mg) per dose every eight hours and acetaminophen 650 mg every six hours if taken together, assuming normal kidney and liver functions,” according to Dr. Massachi.

There are a variety of doses for ibuprofen and acetaminophen. The standard dosage for OTC ibuprofen is 200-400 mg every six hours. Adults should not take more than an absolute maximum of 3,200 mg of ibuprofen per day. Given the potential for adverse effects with higher doses in many patient populations, patients should take the smallest dosage needed to alleviate pain. Patients should start with lower doses, achieving doses no greater than 1,200 mg per day, prior to pushing doses to the absolute maximum daily dose of 3,200 mg per day. It is important to pay close attention to the package labels when taking OTC ibuprofen or acetaminophen. It is especially important to pay attention to the age of the person taking the medication. Children have different recommended dosages than adults. It is a good idea for parents with concerns to talk to a pharmacist or pediatrician when unsure of what dose to give a child.

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Acetaminophen is typically available in strengths of 325-650 mg. A single dose is usually two 325 mg pills taken every six hours. The maximum amount of acetaminophen is no more than 1,000 mg at one time or 3,000 mg within 24 hours. In rare scenarios, a healthcare professional may advise a patient it is safe to take up to 4,000 mg of acetaminophen in 24 hours. Do not use more than the recommended amount of acetaminophen, especially for prolonged periods of time and if not under the advice of a healthcare professional, because it can be harmful to the liver and cause permanent damage.

Always ask a healthcare professional, such as a doctor or pharmacist, if you’re ever unsure how much medicine to take. They can also help you determine which other OTC medications may include “hidden” similar ingredients, such as flu and cold medications.

Side effects of ibuprofen and acetaminophen

It is safe to take these two OTC pain relievers together in the recommended doses. Both pain relievers also come with side effects, and they can be harmful in cases when an overdose occurs.

Side effects of ibuprofen

• Gas or bloating
• Diarrhea
• Constipation
• Ringing of the ears
• Dizziness
• Nervousness
• Increased blood pressure

Side effects of acetaminophen

• Nausea
• Headache or lightheadedness
• Trouble urinating
• Dark stool
• Itching

Rare but serious adverse events of ibuprofen and acetaminophen include allergic reactions (rash, hives, swelling), hoarseness, difficulty breathing or swallowing, and chest pain. Too much ibuprofen can cause gastrointestinal bleeding, and it can worsen stomach ulcers. Severe liver damage may occur with the overuse of acetaminophen. Rare, but serious skin reactions may occur with acetaminophen, such as Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP). These symptoms require medical attention. You should call 911 or seek out an emergency department as soon as possible.

Ibuprofen and acetaminophen: Interactions

There are some risk factors that should be used with caution with ibuprofen and acetaminophen, as well as medications that interact with them. Ibuprofen and acetaminophen should be avoided or taken at a reduced dose when any of these risk factors or medication interactions are present. A healthcare provider should be consulted when there is uncertainty about taking ibuprofen or acetaminophen. 

Interactions with ibuprofen

• Other NSAIDs
• Aspirin
• Blood thinners (warfarin)
• Blood pressure medications (ibuprofen may decrease effectiveness of ACE-inhibitors and diuretics)
• Lithium (ibuprofen may increase risk of Lithium toxicity)
• Methotrexate (ibuprofen may increase risk of methotrexate toxicity)
• Corticosteroids (may increase risk of stomach ulcers or bleeding)
• Tobacco (may increase risk of stomach ulcers or bleeding)
• Alcohol (may increase risk of stomach ulcers or bleeding)
• Pregnancy: ibuprofen should never be taken while pregnant without consulting a healthcare provider first. It should especially be avoided in the third trimester due to heart risks of the fetus (closure of the ductus arteriosus)
• History or risk of stomach ulcers
• History of high blood pressure
• Renal disease
• Elderly or debilitated patients (may increase risk of stomach ulcers or bleeding)
• History of allergic reaction to NSAID or aspirin

Interactions with acetaminophen

• Alcohol
• Disulfiram (alcoholism treatment)
• Acetaminophen-containing OTC products
• Liver disease or liver failure
• History of allergic reaction to acetaminophen
• History of Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP)

RELATED: OTC painkillers with alcohol | OTC painkiller while pregnant

Which is safer: ibuprofen or acetaminophen? 

“One isn’t safer than the other,” says Dr. Massachi. “They both have their own issues and potential for side effects and abuse and must be taken with caution and in appropriate quantities to ensure they are effective while also being non-hazardous. But one isn’t more effective than the other per se, and choosing which drug to take should align with the patient’s symptoms (e.g., fever versus joint pain).”

Mixing OTC pain relievers

Make sure you safely combine OTC pain relievers to avoid complications.

Ibuprofen is an NSAID and should not be combined with other NSAIDs. NSAIDs use the same mechanism in the body. They are all eliminated by the same mechanisms, through the kidneys, and can lead to overdose and severe side effects when combined.

Acetaminophen is not an NSAID and can be safely mixed with NSAIDs such as Advil, Motrin, Aspirin, or Aleve (naproxen). When combining ibuprofen and acetaminophen for acute pain management, only take the recommended dosages.

Be mindful of OTC products that may include NSAIDs and/or acetaminophen as combination formulations, such as medications for cough and cold symptoms or sleep assistance Always ask a pharmacist or healthcare professional if you are unsure of the ingredients of any product.

How do I know if I’ve taken too much? 

If too much ibuprofen or acetaminophen has been ingested, get help right away. It is especially important to urgently seek help in the case of an acetaminophen overdose because it can be fatal. In general, the recommended dose should be taken as the least amount of medication needed should be taken for the least amount of time. These medications should be taken as directed per the package dosage instructions or instructions from a prescriber. To avoid unwanted effects and risk of overdose, high doses should be avoided or used minimally. The daily maximum dosage should never be exceeded.

Symptoms of ibuprofen overdose

• Upset stomach
• Gastrointestinal bleeding
• Kidney damage
• Depressed mood
• Apnea (difficulty breathing)
• Metabolic acidosis
• Life-threatening hypokalemia (low potassium)
• Thrombocytopenia (low platelet level)

Symptoms of acetaminophen overdose

• Nausea
• Vomiting
• Excessive sweating
• Malaise
• Liver toxicity
• Hypoglycemic coma
• Thrombocytopenia (low platelet level)

Remember, if an overdose is suspected, it is important to get medical help right away. Severe liver damage caused by acetaminophen sometimes takes 48-72 hours to take effect and may not be evident at first. 

References

• Ibuprofen and acetaminophen for postoperative pain, Cochrane Review published on the National Institutes of Health (NIH)
• Ibuprofen and Acetaminophen combination as effective as opioids, Harvard
• Use caution with pain relievers, Food and Drug Administration (FDA)
• Motrin package insert, Food and Drug Administration (FDA)
• Acetaminophen package insert, Food and Drug Administration (FDA)
• Ibuprofen toxicity, National Institutes of Health (NIH)

Ibufen – instructions for use, doses, side effects, reviews of the drug:

Description of the drug Ibufen (oral suspension, 100 mg / 5 ml) is based on the official instructions, approved by the manufacturer in 2004

Date approval: 27.07.2004

Contents

• Active substance
• ATX
• Pharmacological group
• Nosological classification (ICD-10)
• Composition and form of release
• Description of the dosage form
• Pharmacokinetics
• Indications
• Contraindications
• Dosage and administration
• Side effects
• Interaction
• Overdose
• Precautionary measures
• special instructions
• Storage conditions
• Best before date
• Reviews

Active ingredient

Ibuprofen* (Ibuprofen*)

ATX

M01AE01 Ibuprofen

Pharmacological group

NSAIDs – Derivatives of propionic acid

Nosological classification (ICD-10)

ICD-10 code list

Composition and formulation

in orange glass bottles of 100 g; in a box 1 bottle (a measure with a scale is attached to the package).

Description of dosage form

Suspension of orange color with an orange smell and sweet taste, with a slightly perceptible burning aftertaste. There may be a separation into a liquid layer and a precipitate, which, after mixing, constitute a homogeneous suspension.

Pharmacokinetics

After oral administration, more than 80% is absorbed from the gastrointestinal tract. max “> C _max in blood plasma is achieved when taken on an empty stomach – after 45 minutes, when taken after a meal after 1.5–2.5 hours. Protein binding – 90%. It slowly penetrates into the joint cavity, but in the synovial fluid it creates concentrations higher than in the blood plasma (C _max in the synovial fluid is reached after 2-3 hours). Metabolized mainly in the liver. It undergoes pre- and post-systemic metabolism. After absorption, about 60% of the pharmacologically inactive R-form is slowly transformed into the active S-form. Excreted by the kidneys (60-90% in the form of metabolites and products of their combination with glucuronic acid, to a lesser extent – with bile, unchanged – no more than 1%). Has biphasic elimination kinetics with 1/2″>T _1/2 2–2.5 hours, after administration in a single dose, completely eliminated within 24 hours. The antipyretic effect of Ibufen develops after 30 minutes and lasts 6–8 hours. colds, acute respiratory viral infections, influenza, tonsillitis (pharyngitis), childhood infections accompanied by fever, post-vaccination reactions.

As an analgesic: for toothache, painful teething, headache, migraine, neuralgia, muscle and joint pain, trauma and burns.

Contraindications

Hypersensitivity (including to acetylsalicylic acid or other NSAIDs), peptic ulcer of the stomach and duodenum, severe insufficiency of the liver, kidneys, cardiovascular system, arterial hypertension, hemophilia, hypocoagulation, hemorrhagic diathesis, glucose deficiency -6-phosphate dehydrogenase, bronchospastic reactions after the use of acetylsalicylic acid or other NSAIDs (“aspirin asthma”), Quincke’s edema, nasal polyps, hearing loss, infancy (up to 6 months, with body weight – below 7 kg).

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

By mouth , after eating. The average single dose is 5-10 mg/kg of body weight 3-4 times a day. Children aged 6 months – 1 year (7-9 kg) – 2.5 ml (50 mg) 3 times a day, the maximum daily dose is 7.5 ml (150 mg). 1-3 years (10-15 kg) 2.5 ml (50 mg) 3-4 times a day, maximum daily dose is 7.5-10 ml (150-200 mg). 3-6 years (16-20 kg) – 5 ml (100 mg) 3 times a day, the maximum daily dose is 15 ml (300 mg). 6-9 years (21-30 kg) – 5 ml (100 mg) 4 times a day, the maximum daily dose is 20 ml (400 mg). 9-12 years (31-41 kg) – 10 ml (200 mg) 3 times a day, the maximum daily dose is 30 ml (600 mg). Over 12 years (more than 41 kg) – 10 ml (200 mg) 4 times a day, the maximum daily dose is 40 ml (800 mg). The dose can be repeated every 6-8 hours. Do not exceed the maximum daily dose. For children from 6 months to 1 year, the drug is prescribed on the recommendation of a doctor.

Side effects

From the side of the central nervous system: headache, dizziness, sleep disturbance, anxiety, drowsiness, depression, agitation, visual impairment (reversible toxic amblyopia, blurred vision or double vision).

From the side of hematopoiesis: heart failure, tachycardia, increased blood pressure; anemia, thrombocytopenia, agranulocytosis, leukopenia.

From the digestive tract: nausea, vomiting, loss of appetite, heartburn, abdominal pain, diarrhea, constipation, flatulence, abnormal liver function, peptic ulcers, gastric bleeding.

From the urinary system: acute renal failure, allergic nephritis, nephrotic syndrome (edema), polyuria, cystitis.

Allergic reactions: itching, rash, bronchospastic syndrome, allergic rhinitis, angioedema, Steven-Johnson syndrome, Lyell’s syndrome.

Interactions

Information for healthcare professionals only.
Are you a healthcare professional?

Should not be combined with other NSAIDs (acetylsalicylic acid reduces anti-inflammatory effect and increases side effects). When taken simultaneously with diuretics, the diuretic effect decreases and the risk of developing renal failure increases. Weakens the effect of antihypertensive drugs, incl. ACE inhibitors (simultaneously reduces their excretion by the kidneys), beta-adrenergic agents, thiazides. Enhances the effect of oral hypoglycemic agents (especially sulfonylurea derivatives) and insulin, indirect anticoagulants, antiplatelet agents, fibrinolytics (increases the risk of hemorrhagic complications), the toxic effect of methotrexate and lithium preparations, increases the concentration of digoxin in the blood.

Microsomal oxidation inducers (phenytoin, ethanol, barbiturates, zixorin, rifampicin, phenylbutazone, tricyclic antidepressants) increase the risk of developing severe hepatotoxic complications (increase the production of hydroxylated active metabolites), microsomal oxidation inhibitors reduce it. Caffeine enhances the pain-relieving effect.

Overdose

Symptoms: abdominal pain, nausea, vomiting, lethargy, headache, tinnitus, depression, drowsiness, metabolic acidosis, hemorrhagic diathesis, decreased blood pressure, acute renal failure, abnormal liver function, tachycardia, bradycardia , atrial fibrillation; convulsions, apnea and coma (especially characteristic of children under 5 years of age).

Treatment: gastric lavage, administration of activated charcoal, alkaline drink, symptomatic therapy (correction of acid-base balance, blood pressure).

Precautions

Use with caution in cirrhosis of the liver with portal hypertension, hepatic and/or renal insufficiency, heart failure, nephrotic syndrome, hyperbilirubinemia, gastric and duodenal ulcer (history), gastritis, enteritis, colitis, diseases blood (leukopenia, anemia), pregnancy (II-III trimesters), during breastfeeding. In patients with bronchial asthma or other diseases that occur with bronchospasm, there may be an increased risk of developing bronchospasm.

During long-term treatment, it is necessary to control the picture of peripheral blood and the functional state of the liver and kidneys. When symptoms of gastropathy appear, careful monitoring is indicated (conducting esophagogastroduodenoscopy, a blood test with the determination of hemoglobin, hematocrit, fecal occult blood analysis).

If there is no antipyretic effect within 2 days and no analgesic effect within 3 days, you should consult a doctor. In case of side effects, stop taking the drug and consult a doctor.

Special instructions

Shake the vial before use until a homogeneous suspension is obtained. With prolonged use, NSAIDs can cause damage to the gastric mucosa, peptic ulcers, and gastrointestinal bleeding.

Use with caution in diabetic patients – contains sugar.

If side effects occur, stop taking the drug and consult a doctor.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 ° C, in the original packaging.

Keep out of reach of children.

Expiry date

3 years.

Do not use after the expiry date which is stated on the package.

Update date: 05/24/2022

Alevé vs Motrin: difference and comparison

There are a huge number of medicines in the world that are taken for medicinal purposes. Drugs help our body relax by relaxing muscles and relieving stress. An ingredient in drugs or medicines initiates our sleep, which causes relaxation and decades of pain. Therefore, most painkillers drive us into a sound sleep after taking them.

Health Quiz

Test your knowledge on health-related topics

1 / 10

Vitamin D is sometimes called:

The sleepy vitamin

The “bad” vitamin

Sunny Vitamin

Dark Vitamin

2 / 10

What are the 5 food groups in a balanced diet?

Fruits, vegetables, cereals, proteins, dairy products

Fruits, vegetables, meats, dairy products, sweets

Fruits, vegetables, carbohydrates, proteins, dairy products

Fruits, vegetables, carbohydrates, meats, dairy products

3 / 10

What is the best way to protect yourself from the harmful rays of the sun?

Wear a hat

Apply sunscreen

Wear sunglasses

All of the above

4 / 10

Foods containing sugar and starch. Most of your energy comes from such food. Products with natural sugar or starch are the best source of such food.

Cookies

Starches

carbohydrates

Vitamins

5 / 10

White blood cells that attack pathogens are called ______________.

Neurocytes

Lymphocytes

Carcinogens

None of these

6 / 10

How many hours of sleep is recommended for an adult?

4 hours

6 hours

8 hours

10 hours

7 / 10

What is the recommended daily intake of fiber for an adult?

10 grams

20 grams

30 grams

40 grams

8 / 10

What is the main cause of chronic obstructive pulmonary disease (COPD)?

Genetics

smoking

Air pollution

All of the above

9 / 10

What is the main function of the respiratory system in the body?

For blood pressure regulation

To fight infections

To transport oxygen and remove carbon dioxide

To remove waste products

10 / 10

How many chambers are there in the heart?

your account

Aleve and Motrin are brands that make pain relievers or pills to relieve pain. These include tablets, gel, ointments, liquid syrup, etc., taken during pain. Regular doses of these pain relievers will treat pain such as headache, abdominal pain, toothache, etc. for some time. But for chronic pain, the doses recommended by the doctor should be taken.

Key Findings

1. Aleve is a brand name for naproxen and Motrin is a brand name for ibuprofen.
2. Aleve provides longer lasting pain relief than Motrin.
3. Motrin is available without a prescription, while Aleve is available with and without a prescription.

Aleve vs Motrin

Aleve is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing inflammation in the body, providing longer lasting pain relief. Motrin is an NSAID that reduces inflammation in the body, commonly used to relieve mild to moderate pain, fever, and inflammation. Its effects last from four to six hours.

Aleve is the brand name for ibuprofen. This drug is commonly used to reduce pain, and doctors most often recommend it as a pain reliever for acute or chronic pain. It is also known as naproxen because naproxen acts as its main ingredient. Large doses or abnormal doses of this drug can lead to heart disease, stomach ulcers, gastrointestinal bleeding, etc.

Motrin belongs to the category of non-steroidal anti-inflammatory drugs, which are mainly used to reduce pain, treat fever, etc. This drug is also used in children under ten years of age because it is less dangerous. The doses of this drug depend on the level of pain and the body type of the person. And also, if a person suffers from other diseases, he should not take these types of medicines without a doctor’s prescription.

Comparison table

Comparison parameters	Aleve	Motrin 9 0228
Active ingredients and their vital ingredient is naproxen sodium.	Motrin is the generic name for an ibuprofen-based drug and its main ingredient is ibuprofen, often referred to as propionic acid.
Doses	People are usually advised to take pills, liquid, etc. every seven to twelve hours as long as the pain lasts. But in case of severe pain, you should consult a doctor.	It is usually taken four to six hours later until the pain is gone. Limited to 200 to 400 mg.
Side effects	These include side effects such as headache, stomach pain, itching in some parts of the body and fatigue, etc.	Side effects may include anxiety, restlessness, fatigue, constipation, etc.
Used for	This medicine is usually used to treat normal pain or acute pain such as menstrual pain, headache, etc.	It is also used for minor pains such as headache, toothache, arthritis, etc. But it can also be used for pain during fever.
Long lasting	Aleve is very effective in reducing pain and lasts about twelve hours.	Motrin takes 20 to 30 minutes to relieve pain. And its result lasts about three to six hours.

What is Alev?

Aleve sells a drug called naproxen under its own brand name. It reduces pain within one hour and can last up to 12-13 hours. Most often, these are tablets that are taken by mouth. It is mainly used to treat inflammatory pain caused by irritation in parts of the body, but can also be used to treat chronic muscle pain and back pain.

Aliv can be taken without a doctor’s recommendation, but in small amounts and irregularly. If the pain persists, a doctor should be consulted for proper treatment. This drug can harm the body if taken incorrectly and cause heart attack and other stomach problems. A woman mainly uses this medicine when they have menstrual cramps.

Aleve comes in two types, one is immediate release and the other is extended release, where immediate release is used for general pain as it acts immediately and relieves pain, while extended release does not provide immediate results, but for chronic pain it does. the best option.

What is Motrin?

Motrin is the most popular OTC drug. It acts instantly within twenty to thirty minutes and is less dangerous for babies than Aleve. It is usually taken as a tablet, but it can also be given by injection or intravenously. The main ingredient in this drug is ibuprofen, also known as isobutyl-phenyl-propionic acid or simply propionic acid.

Motrin should be taken in limited amounts as the side effects of this drug persist, including headache, vomiting, diarrhea, etc. to high blood pressure. Motrin is easily absorbed and excreted in the urine within 24 hours.

Ibuprofen was created in 1961; it was previously known as Brufen. Stuart Adams and John Nicholson founded this drug formula. On the market, it is sold under different brands such as Nurofen, Motrin, etc.

The main differences between Aleve and Motrin

1. Aleve is the name of the company under which the drugs are sold, and their vital ingredient is naproxen sodium . On the other hand, Motrin is the generic name for the drug ibuprofen, and its main ingredient is ibuprofen, often referred to as propionic acid.
2. Motrin takes 20 to 30 minutes to relieve pain. And its effect remains for about four to six hours. While Aleve is very effective in reducing pain and its effect lasts for about twelve hours.
3. Aleve includes side effects such as headache, abdominal pain, itching in some parts of the body, fatigue, etc. In comparison, Motrin side effects can include restlessness, restlessness, fatigue, constipation, etc.
4. Motrin is usually taken four to six hours later until the pain is gone and the amount is limited to 200-400 mg. Whereas, it is generally recommended that people take Aleve every seven to twelve hours as long as the pain lasts. But in case of severe pain, you should consult a doctor.
5. Aleve is usually used to treat normal pain or acute pain such as menstrual pain, headache, etc. In comparison, Motrin is used for minor pain such as headache, toothache, arthritis, etc.