Bisacodyl (Dulcolax) | Advice, Dosage, and Side-Effects

Bisacodyl

Dulcolax, Sovolax

In this article

• What is bisacodyl?
• Before using bisacodyl
• How to use bisacodyl
• Getting the most from your treatment
• Can bisacodyl cause problems?
• How to store bisacodyl
• Important information about all medicines

What is bisacodyl?

Constipation can be caused by a poor diet, not drinking enough water and not going to the toilet as soon as you feel you need to. Pregnancy, a lack of exercise or movement (such as being ill in bed) and some medicines, including some painkillers, can also cause constipation.

However, many people take laxatives when they do not need to because they believe that they are constipated unless they go to the toilet every day. This is not the case. A useful definition of constipation is going to the toilet less frequently than is normal for you, and passing hard stools (faeces) when you do go.

Bisacodyl works by encouraging the muscles in your bowel to move stools through your body. This helps you to go to the toilet. Tablets usually have an effect within 10-12 hours. Suppositories will take between 10-60 minutes to work, but usually have their effect within 30 minutes. Bisacodyl preparations are available to buy without a prescription at pharmacies and other retail outlets.

Bisacodyl is sometimes used to clear the bowel before a medical examination which requires the bowel to be empty. When it is used like this, you will be provided with a small supply of bisacodyl by your hospital or clinic.

Before using bisacodyl

To make sure this is the right treatment for you, ask for advice from a doctor or pharmacist before you start using bisacodyl if any of the following apply to you:

• If you are pregnant, trying for a baby or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
• If it is for a child under 10 years of age. This is because bisacodyl should only be given to children on the advice of a doctor or healthcare professional.
• If you have severe pain in your tummy (abdomen) and feel sick (nausea).
• If you have recently had any bowel or abdominal surgery.
• If you are lacking in fluid in the body (dehydrated) or take ‘water tablets’ (diuretics).
• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
• If you have ever had an allergic reaction to a medicine.

How to use bisacodyl

• Before you start this treatment, read the manufacturer’s printed information leaflet from inside your pack. The leaflet will give you more information about bisacodyl and a full list of side-effects which you may experience from taking it.
• Take one or two 5 mg tablets with a drink of water (do not take with milk). Bisacodyl tablets take about 10-12 hours to work; therefore, they are best taken at bedtime. Do not chew or break the tablets.
• A suppository can be used instead of taking tablets. Use one suppository daily. It will take between 10-60 minutes to work and therefore should preferably be used in the morning. It will usually have its effect within 30 minutes. There are two strengths of suppository: 10 mg which is suitable for adults, and 5 mg which is suitable for older children (and younger children when prescribed by a doctor).
• Bisacodyl should only be used for a short time. This is because your bowel can start to rely on this type of laxative to make it work rather than working on its own. If you are still constipated after taking bisacodyl for five days, you should speak with your doctor.
  

How to use a suppository

1. Remove the suppository from the wrapping.
2. Moisten the suppository with a little tap water.
3. Using your finger, gently push the suppository into the back passage (rectum) as far as is comfortable.
4. Remain still for a little while to help hold the suppository in place. It will start to work in about 20 minutes or so.
5. Wash your hands after use.

Getting the most from your treatment

• Do not take indigestion remedies at the same time as bisacodyl tablets. This is because bisacodyl tablets have a special coating on them which is affected by antacid preparations. If you need to take something for indigestion, make sure you take it more than two hours before you take bisacodyl, or alternatively wait for two hours after you have taken bisacodyl.
• A healthy diet containing fibre (whole grain breads and cereals, bran, fruit and green leafy vegetables) with six to eight full glasses of water each day and daily exercise are important in maintaining healthy bowel function.
• You can read more about how to prevent or treat constipation in the separate leaflets called Constipation (for adults) and Constipation in Children.

Can bisacodyl cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Important: do not use bisacodyl for more than five days without speaking to your doctor or a pharmacist. Overuse of stimulant laxatives is harmful; it leads to loss of fluids and can make you dehydrated. It can also prevent your intestines from working properly. Signs you are dehydrated include feeling thirsty, dark urine, shaky or weak muscles, blurred vision and fainting

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store bisacodyl

• Keep all medicines out of the reach and sight of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

• Manufacturer’s PIL, Dulcolax® Twelve Plus 5 mg Gastro-resistant Tablets; Sanofi, The electronic Medicines Compendium. Dated August 2020.

• Manufacturer’s PIL, Dulcolax® Twelve Plus 10 mg Suppositories; Sanofi, The electronic Medicines Compendium. Dated September 2020.

• Medicines Complete BNF 85th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London.

Effectiveness, Ease of Use, and Satisfaction

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Most voted positive review

30 People found this comment helpful

This product is effective. Take only one at a time (i took two once and was crying in pain). You should also plan to take it only when you can afford to have some quality bathroom time. You may need a few trips to the bathroom as it works through your system. Don’t take it the day that you have something really imortant to do. I took it at 9 p.m. and it worked its way through at about 10 a.m. …

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Most voted negative review

5 People found this comment helpful

I had received free samples of Dulcolax laxative tablets and took one two nights ago around 10PM. I woke up in the morning with moderate cramping, and while on my commute was feeling uncomfortable. I had jury duty that morning and as soon as the case began, I started feeling incredibly nauseous and hot, as well as crampy, and hobbled embarrassingly to the bathroom. There I stayed for 30 minutes hu…

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SORT BY Condition: Incomplete or Infrequent Bowel Movements

Overall rating 1. 0

EffectivenessEase of UseSatisfaction

I will never use this again. Why would anyone when a fleet enima produces a bowel movement with no pain? I am usually very regular but had a medical treatment that slowed everything down. I hadn’t had more than a small BM in 5 days but they were not hard. So I decided a stimulant was needed to get things moving again and that it wouldn’t be painful because I wasn’t having hard stools. Oh my god. I used a suppository because why put it through your whole system. I was in complete agony. Sweat literally dripping off of me and making a puddle on the floor. So much cramping my body didn’t know what to do. I laid on the floor for a few minutes and seriously considered just pushing while I was there instead of moving to the toilet because I’d pass out or vomit or both. This does not cause stomach cramps. This does not cause mild cramps. This causes severe cramps that trigger a vasovagal response, sweating, nausea, light headed out fainting. The passing of the stool isn’t causing the symptoms the cramping induced by this medication does. I have pelvic floor disfunction so my muscles are too tight. Maybe that’s what predicts who will have severe cramping. I will never take this again. Yes it stimulated my bowel but far more than necessary to just have a bowel movement. I did a full bowel prep for surgery with zero cramping. I would rather do that process again than take this product. It is not necessary and I don’t think it should even be on the market. The label just lies. Mild stomach cramps? Your stomach doesn’t cramp to make you poop. Your colon and rectum cramps to make you poop. The label needs to say severe intestinal cramping possible. I would NEVER give this to a child. I can’t believe it says you can give it to kids 6 and older. Do not do it. If nothing else works, call you doctor.Read More Read Less

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Overall rating 1.0

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WHERE DO I BEGIN???
I have kidney issues so that gets me backed up often. Came home from work around 10am 3/37/2023. Told myself i would take it soon as i get home so i can have BM then shower. The box says take 1-3, so i took the median, 2. Sat on couch to play playstation and wait for lax to kick in. 30 minutes into the game i start to feel confusion and dizzyness. Had to turn it off and lay down as i didnt know why i was feeling this way. Nausea kicked in literally 2 minutes after i laid down and i had to pop up and rush to the bathroom. Barely closing the door i could only make it to the bathtub, because the tub is closer then the toilet, i violently vomited for the next 30 minutes. Had to lay on my bathroom floor with a pillow my girl brought, for the next hour, as im still waiting for bowel movement. However the burning feeling in my stomach i did not sign up for. Im laying on the bathroom floor next to my cat litter. Cat comes in to take a wiz next to my face. Body extremely hot, stomach cramps, weak, dizzy, list goes on. But still havnt had the urge for BM yet. Sweating, so i take off my long john top n bottom. Then chills come in, like wtf. Still laying on the floor because im too dizzy to stand up for longer then 10 seconds. I go lay down in bed because my hips were hurting from the floor. Drank two bottles of poland spring which felt like it made it worse. 1pm rolls around and now stomach starting to bubble. Severe stomach cramps every 5 minutes or so.along with every other symptom. Another hour later it felt like it was time to go. Sat on toilet for first session, that lasted 30 seconds as i had to immedietly drop to the floor from the toilet because i felt like fainting. (Couldnt even wipe first). Now im naked on the cold bathroom floor again, same symptoms. Fainted twice on floor. 3pm The same process again.Laid in bed, threw up another ten times. Then BM.12 hours, 4 am, on my 6th toilet session, its down to watery stools. Symptoms gone, only feel funny in my stomach. Right Now 11am next day, gassy stomach and dry mouth. Cant eat nothing. Just ginger ale. Honestly felt like calling 911 yesterday. DO NOT TAKE THIS CRAP. Unless you like the feeling of death..ide take the electric chair first….NEVER AGAIN!!!!!Read More Read Less

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Overall rating 4.0

EffectivenessEase of UseSatisfaction

Well, where to start. Firstly, yes they are effective. But at a cost.. I took 2 tablets at around 10pm.. by 2:30am I was woken by mild stomach cramps.. sat awake for 15 mins and then decided it was time.. headed to the bathroom and oh dear. The pain was excruciating as the cramps intensified. Then came waves of nausea and sweats.. after half hour I finally managed to release the blockage. I would recommend 1 tablet only.

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Overall rating 4.0

EffectivenessEase of UseSatisfaction

I read the reviews of others. Everyone’s body is different because I didn’t experience any cramping, sweating, nausea, light headedness, etc. I took it at 5PM. It did take about 10 hours to take effect(pill) but it was very gentle and gave me a good start to cleanse in prep for my colonoscopy tomorrow.

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Overall rating 3. 3

EffectivenessEase of UseSatisfaction

Ok, i am a very big female. And I am very constipated all the time, this is my first time and I took only one pill. There is some nausea, some heartburn, a little sharp pain on the side. That’s all, and some of the people on these reviews are dramatic, it’s not as bad.??

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Overall rating 3.0

EffectivenessEase of UseSatisfaction

The liquid version was the best, because it enabled me to have a bowel movement within one or two hours.
But I had to be very careful with how much I did take, because one full dose gave me stomach cramps and some serious diarrhea which lasted for a few hours.
In regards to the pill form, it depends on which type of pills you take.
The women’s formula wasn’t that great, however, I can say that the small pink pills worked best.
Overall, I found more success by taking magnesium supplements, and utilizing an enema bag with warm soapy water, when I’ve been seriously constipated. Read More Read Less

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Overall rating 4.7

EffectivenessEase of UseSatisfaction

I’ve been clockwork regular all my life. Started having 1-2 C tea before bed a few weeks ago and became constipated. About 10 days w very little to any BM. Picked up a small pack of Dulcolax to try before calling Dr. Directions say1-3 tablets w water….after 10 days I decided on two at 5 pm yesterday. Went to bed at 9 pm and woke up w serious stomach cramps at 10pm. Had to go but couldn’t till 10:30 and the dam broke. 7 BM’s the next hour and RELIEF!! Had a stomach ache for another hour but slept well and woke up feeling 10 pound lighter. It works!! Read More Read Less

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Overall rating 5.0

EffectivenessEase of UseSatisfaction

Folks, this stuff works. Took in the am and had a cup of hot chocolate. Within 2 hours I had the urge. I had to push for sure but I was able to go. I put feet on a stool and swayed back and forth. I gave birth to a tennis ball size piece of poop. I just tried to relax and breath.

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Overall rating 1.7

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Dulcolax makes me violently ill. It causes bad stomach cramps and nausea, then violent diarrhea. I recommend using Peri- Colace instead.

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Overall rating 1.7

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I have IBS-C but my new health insurance doesn’t cover my Linzess and it’s like $500 a month out-of-pocket. I obviously can’t afford that so I decided to give this a try. I couldn’t go to the bathroom, so I took Dulcolax around 10 pm before bed. Around midnight, I had a BM, but it was still hard poops. Then around 1-2 am, I was in agonizing pain with cold sweats and nausea. I threw up and got diarrhea for a bit. Then I felt good enough to get some sleep but I woke again around 6 am with the same symptoms. I vomited and got diarrhea again and then felt a little better. It will produce a BM but I don’t think it’s worth the pain. Going to see my doctor and ask if there’s any more gentle alternatives because I think advertising this as gentle is false advertising. Read More Read Less

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Unless you enjoy severe pain steer clear! I’ve had two natural babies with no pain meds/epi, ruptured gallbladder and appendix (not at once) and this Med is still worse!! I woke up in excruciating pain, in and out of consciousness, vomiting, sweating profusely and my body was convulsing! I would never recommend this to anyone!

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Overall rating 5. 0

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I use the Dulcolax pink pills which are made to be easier on the stomach. I have had no issues at all taking them. I use 3 a day (that’s just me, you should start with lowest dose). Depending on what I’m eating, it can work as soon as 5-6 hours. Longest time has been 10-12 hours. I personally have had no pain, cramping , nausea or anything else. I do watch my diet and eat few, if any very refined foods, no fast food or foods made with flour like bread, pasta or things people normally eat. Little if any cheese ( that’s like cement in your bowels). You can’t eat a crappy diet (no pun intended), and expect to have a healthy bowel system or relieve it by taking Dulcolax. I’m a senior with slower digestion at this time of life, so I have to watch what I eat. Stress can cause constipation even if you eat a pure vegan diet, there are many factors and everyone is different. If I use a store brand equivalent, which I did once as the Dulcolax was not available one time, I had also been eating things I usually didn’t. I had serious cramping over several hours in the middle of the night and it was painful and terrifying, with little movement, so to speak. I like to enjoy life too, and sometimes fall off my usual food program. But if I do, I personally have no issue with Dulcolax. Read More Read Less

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Overall rating 4.0

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I took one tiny pill and 2 days and 5 bowel movements later I am still having terrible stomach pain and even lower right back pain, I will find something that does not hurt worse than the constipation

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Overall rating 5. 0

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take it as late as possible b 4 bed … drink lots of water and mk sure u r free to go to the loo next 6 hrs .. it will tk effect 6 hrs-8hrs later..
will mk u feel light after all cleared !!!

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Overall rating 3.7

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Tiny green pills of doom. I’m a 21yr old female 5’5 155lbs. No bm in 4 days. I had never take this before but no stool softener I have tried has worked. It suggests 1-3 so I took 2 as a medium option. DON’T take 2. Please just start out with one. Woke up with the worst sour upset stomach I was so uncomfortable, cold sweats, shaking, yadayada. Just stick near a toilet and take during the day (or you’ll be up all night). Take on a day you can stay at home. Overall, yeah it works. Just tread lightly.Read More Read Less

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Overall rating 5.0

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Have been constipated for around 6 days as I am pregnant, took 2 tablets around 7:30am and had 2 bowel movements – one at 10am and one at 2pm. Mild cramping but nothing major. Definitely works

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I Morine Barnes is prescribed 2x5mg Dulcolax Laxative Tablets nightly for constipation. It as been 72 hours and o have not emptied my bowels. Dulcolax Laxative Tablets does not work for me. I drink plenty of water, vegetarian, exercise gym and walk 1 hour daily Dulcolax Laxative Tablets does not work for constipation. I also bought Dulcolax Laxative Tablets they still did not work.

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Overall rating 4.0

EffectivenessEase of UseSatisfaction

I’m writing this review for the people like myself who read the reviews after taking these. This was my experience: I took 2 pills for constipation at 1pm with some water, avoided dairy all day. Around 5pm, I feel the need to fart. Was not a fart (RIP one of my sheet sets). Luckily I was home, so I run to the bathroom and have a quick watery poop. Since I haven’t pooped in over 2 weeks, I knew this was no way the end of it. I get some mild cramps around 7pm and run to the bathroom and have a real poop that feels like I’m releasing half my body weight. After about 20 minutes I feel super relieved, no cramps/sweats, nothing. I was a little scared to go to sleep after the 5pm incident but I woke up feeling great and back to normal. Read More Read Less

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Overall rating 4.7

EffectivenessEase of UseSatisfaction

I took 2 pills at 5 p.m. and had some cramping and nausea around 7-9 p.m. but it wasn’t bad. I had my first BM at 9 p.m., then a second at 12. I went to bed and was woken up at 5:30 a.m. with cramping and had a BM then another at 6:30. A few hours later I still had some light cramping, but besides that I felt fine. Reading the other reviews I’m surprised I didn’t have a worse experience for taking 2 pills and weighing 120 pounds. But I did drink about 65 Oz of water and tea over the duration which probably helped a lot.Read More Read Less

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Overall rating 5.0

EffectivenessEase of UseSatisfaction

I couldn’t have a bowel movement for 4 days and tried other laxatives first. They did not work so I found dulcolax. I took one pill in the morning and nothing really happened. 20 hours later, I decide to take 2 pills and had a great bowel movement 12 and 16 hours later. Dulcolax saved me from going to ER since I was in severe pain while constipated. Dulcolax made my stool soft and strain free to pass. I’ll never forget the relief this product gave me.

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Dulcolax 5 mg No. 30 tab

Instructions for medical use
medicinal product
Dulcolax

Trade name
Dulcolax

International non-proprietary name
Bisacodyl

9000 2 Dosage form
Sugar/enteric coated tablets 5 mg

Composition
One tablet contains
active substance – bisacodyl 5 mg,
excipients: lactose monohydrate, corn starch, soluble starch, glycerol 85%, magnesium stearate,
shell composition: magnesium sterate, sucrose, talc, gum arabic, titanium dioxide, methacrylic acid-methyl methacrylate copolymer (1:1) (Eudragit L 100), methacrylic acid-methyl methacrylate copolymer (1:2) (Eudragit S100), castor oil , macrogol 6000, yellow iron oxide E172, white wax, carnauba wax, shellac.

Description
Tablets are round, beige-yellow, biconvex, film-coated, with a smooth, shiny surface and a white core.

Pharmacotherapeutic group
Laxative
ATC code A06AB02

Pharmacological properties
Pharmacokinetics
After application, bisacodyl is rapidly hydrolyzed to the active component bis-(p-hydroxyphenyl)-pyridyl-2 methane (BHPM), mainly by enzymes present on the surface of the intestinal mucosa . Peak VHPM plasma concentrations occur between 4-10 hours after administration, while the laxative effect occurs on average between 6-12 hours after administration. Therefore, the laxative effect of bisacodyl does not correlate with the plasma level of BHPM, instead BHPM acts in the lower intestine and there is no relationship between the laxative effect and the plasma level of the active ingredient. In this regard, sugar/enteric coated tablets are made resistant to the action of gastric juice and small intestine. This contributes to the fact that the action of the drug occurs at the desired site of action – in the large intestine.
Absorption – small, mainly conjugated almost completely in the walls of the intestine and liver, releasing inactive BHPM glucuronide. The half-life of HHRM glucuronide is 16.5 hours.
Excretion – about 10.5% of BHPM glucuronide through the genitourinary tract and about 51.8% of free BHPM- through the gastrointestinal tract.
Pharmacodynamics
Dulcolax is a locally acting laxative from the group of diphenylmethane derivatives. As a contact laxative for which an antiresorptive laxative effect has also been described, Dulcolax, after hydrolysis in the colon, stimulates intestinal motility and increases the accumulation of fluid and electrolytes in the lumen of the colon. This leads to stimulation of defecation, reduction of the transit period and softening of the stool.

Indications for use
constipation due to hypotension of the colon
bowel cleansing in terms of preoperative preparation and postoperative treatment
preparation for instrumental and radiological examinations

Dosage and administration
For constipation:
Adults and children over 10 years old 1-2 each tablets (5 – 10 mg) 1 time per day.
Children aged 4 to 10 years: 1 tablet (5 mg) once a day.
In children under 10 years of age with chronic and prolonged constipation, the use of the drug is possible only on prescription.
Tablets are recommended to be taken at night for the appearance of stools the next morning. Swallow the tablets whole with a sufficient amount of liquid.
It is not recommended to take the tablets with upper GI deacidifiers such as milk, antacids or proton pump inhibitors to prevent premature dissolution of the tablet shell.
Preparation for instrumental and radiographic examinations:
For preoperative preparation, postoperative treatment and preparation for instrumental and radiological examinations, the drug should be taken under medical supervision.
To achieve a complete bowel movement, the recommended adult dose of Dulcolax is 2-4 tablets the night before the study, followed by 1 suppository (10 mg) in the morning before the study.

Side effects
Rare
abdominal cramps and discomfort, diarrhea, vomiting, nausea, anorectal discomfort, colitis
allergic reactions (including anaphylactic shock, angioedema)
Extremely rare
dehydration, blood in the stool
dizziness, fainting (see “Special Instructions”).

Contraindications
hypersensitivity to bisacodyl or other components of the drug
severe dehydration
intestinal obstruction, intestinal obstruction, acute inflammatory diseases of the abdominal cavity, including appendicitis, acute inflammatory bowel disease, severe abdominal pain, accompanied by nausea and vomiting, which may indicate a serious illness0003 hereditary fructose intolerance, galactosemia, glucose, galactose malabsorption syndrome
children under 4 years of age

drug interactions
The combined use of diuretics or adrenocorticosteroids may increase the risk of fluid and electrolyte imbalance if the recommended dose of the drug is exceeded. Electrolyte imbalance can lead to increased sensitivity to cardiac glycosides.

Special instructions
Daily and long-term use of the drug Dulcolax without determining the cause of constipation is not recommended, since long-term use of the drug can lead to impaired water and electrolyte balance and hypokalemia.
Loss of fluids can cause dehydration, signs of which may include thirst and oliguria. In patients suffering from fluid loss, where dehydration can be dangerous (renal failure, elderly patients), the use of Dulcolax should only be under medical supervision.
Patients using the drug may find a small amount of blood in the stool, passing by itself.
Patients taking bisacodyl experienced dizziness and/or fainting, presumably related to pain on straining during defecation or a parasympathetic vascular response to abdominal pain associated with constipation, which is not necessarily related to taking Dulcolax.
Fertility, pregnancy and lactation
Many years of experience have shown no side effects during pregnancy.
However, Dulcolax, like all other medicines, should be used with caution during pregnancy, especially during the first trimester. If necessary, the use of the drug should evaluate the potential benefit of therapy for the mother and the possible risk to the fetus.
According to clinical data, neither bisacodyl nor its glucuronides pass into the breast milk of lactating women, so Dulcolax can be used during lactation.
Studies of the effect of the drug on human fertility have not been conducted.
Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous machinery
No data available. However, patients should be aware of the possibility of dizziness or fainting due to the parasympathetic vascular response to constipation-related abdominal pain.

Overdose
Symptoms: diarrhea, dehydration, abdominal cramps, water and electrolyte imbalance, hypokalemia.
If the recommended dose of Dulcolax is exceeded, as well as other laxatives, secondary hyperaldosteronism and urolithiasis may occur. Also, secondary symptoms in relation to hypokalemia associated with chronic abuse of laxatives, cases of metabolic alkalosis, muscle weakness have been described.
Treatment: symptomatic. Fluid intake and correction of electrolyte imbalances may be necessary. This is especially important in the elderly and young. Taking antispasmodics may also be helpful.
Release form and packaging
10 tablets in a blister pack made of polyvinyl chloride film and aluminum foil.
1, 2, 3 or 4 contour packs, together with instructions for use in the state and Russian languages, are placed in a cardboard pack.

Storage conditions
Store in a dry place, at a temperature not exceeding 25°C.
Keep out of the reach of children!

Shelf life
3 years
Do not use after the expiration date.

Pharmacy dispensing conditions
Without prescription

Manufactured by Delpharm Reims S.A.S., France

Name and country of marketing authorization holder
Boehringer Ingelheim International GmbH, Germany

Address of the organization accepting claims from consumers on the quality of products in the Republic of Kazakhstan
Representation of “Boehringer Ingelheim Pharma Ges mbH” in the Republic of Kazakhstan
Legal address: Almaty, 050010, st. Kairbekova 38
Actual address: Almaty, 050008, Abai Ave. 52
Innova Tower Business Center, 7th floor
tel: +7 (727) 250 00 77 fax: +7 (727) 244 51 77
e-mail: [email protected]

DULCOLAX tablets: 17 reviews from real people. All drug reviews on the site

Greetings to all and good mood to you!
However, it – this mood spoils when there are problems with the activity of the intestines. It becomes even more difficult for me if I am away from home, in an unfamiliar environment. For some reason, my body does not accept other people’s toilets, reacts sharply to a change in nutrition, requires the usual water and climate. In general, the body rebels and engages in sabotage.
Knowing this, and my previous not the best experience, when planning a trip, I went to the pharmacy and, on the advice of a pharmacist, bought Dulcolax tablets. The pharmacist said that this tool works flawlessly and gently. The cost of tablets is 251 rubles. The package contains 30 tablets.
I usually buy something after reading my favorite Irecommend. Later I read some negative reviews about Dulcolax. It talked about terrible pains, unbearable diarrhea and terrible troubles. Worried, I got fear…
And then the moment came when I needed help from this small, but such a terrifying pill. I did not sleep half the night, listening to my inner feelings, expecting a stormy and dangerous action.
The surprise was in the morning when I did not experience any pain. But the morning trip to the toilet was easy, relaxed, without any additional sensations. The result was lightness and comfort in the stomach and throughout the body.
Active ingredient
It should be noted that in the drug Dulcolax, the active ingredient is bisacodyl. It belongs to the category of irritants. It is a prodrug, when taken orally in an alkaline environment, hydrolysis occurs with the formation of a substance that irritates the gastrointestinal mucosa (mucus secretion in the large intestine increases, its peristalsis accelerates and intensifies). When taken orally, it takes effect after 6–10 hours; when taken before bedtime, it takes effect after 8–12 hours.
However, such constipation stimulating tablets cannot be used systematically, this can lead to big problems. The intestines will become completely lazy and will not work on their own. In addition, addiction develops and the body will require an increase in the dose. With occasional constipation, you can safely apply. And take into account that pain and other side effects do not occur to everyone. I didn’t have them.
Contraindications long-term use nursing and pregnant women infants abdominal pain of unknown nature acute proctitis acute hemorrhoids intestinal bleeding uterine bleeding cystitis peritonitis acute inflammatory diseases of the abdominal cavity Method of application
1 tablet before bed was enough for me. With what it is not recommended to use: The combined use of the drug Dulcolax in the form of tablets with antacids, as well as with milk and alkaline mineral water, can lead to premature dissolution of the tablet shell and irritation of the stomach and duodenum.