Hydroxychloroquine Sulfate 200: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

09.07.202314.06.2023 by alexxlab

What are the uses of hydroxychloroquine? What are the side effects of hydroxychloroquine? What are the interactions of hydroxychloroquine? What are the warnings and dosing for hydroxychloroquine?

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Uses of Hydroxychloroquine

Hydroxychloroquine is primarily used to prevent or treat malaria caused by mosquito bites. The Centers for Disease Control and Prevention (CDC) provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Patients should discuss the most recent information with their doctor before traveling to areas where malaria is prevalent.

In addition, hydroxychloroquine is also used to treat certain autoimmune diseases, such as lupus and rheumatoid arthritis. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs) and can reduce skin problems in lupus and prevent swelling and pain in arthritis.

It is important to note that hydroxychloroquine is not recommended for the treatment of coronavirus infection, also known as COVID-19, unless the patient is enrolled in a study. Patients should discuss the risks and benefits with their doctor.

How to Use Hydroxychloroquine

Hydroxychloroquine should be taken exactly as directed by the doctor. To help prevent stomach upset, it should be taken with food or milk. The tablets should be swallowed whole, as breaking or crushing them may leave a bitter taste.

The dosage and length of treatment are based on the patient’s medical condition and response to treatment. For children, the dose is also based on weight.

To prevent malaria, patients should take hydroxychloroquine by mouth as directed by their doctor, usually once a week on the same day each week. The medication is typically started 1 to 2 weeks before entering the malarious area, continued while in the area, and for 4 to 8 weeks after leaving the area, or as directed by the doctor.

To treat malaria, patients should follow their doctor’s instructions.

For lupus or rheumatoid arthritis, patients should take hydroxychloroquine by mouth as directed by their doctor, usually once or twice daily. The doctor may gradually increase the dose, and once the condition has improved, the doctor may instruct the patient to lower the dose until the optimal dose with the fewest side effects is found.

If the patient is also taking a certain drug for diarrhea (kaolin) or taking antacids (such as magnesium/aluminum hydroxide), they should take hydroxychloroquine at least 4 hours before or after these products, as they may bind with hydroxychloroquine and prevent the body from fully absorbing it.

Side Effects of Hydroxychloroquine

Common side effects of hydroxychloroquine may include nausea, vomiting, loss of appetite, diarrhea, dizziness, or headache. If these effects persist or worsen, patients should inform their doctor or pharmacist.

Patients should tell their doctor right away if they experience any serious side effects, such as slow heartbeat, symptoms of heart failure, mental/mood changes, hearing changes, easy bruising/bleeding, signs of liver or kidney problems, muscle weakness, or unwanted/uncontrolled movements.

Hydroxychloroquine may also cause low blood sugar (hypoglycemia). Patients with diabetes should be sure to check their blood sugar regularly, and their doctor may need to adjust their diabetes medication.

Interactions and Warnings with Hydroxychloroquine

Patients should inform their doctor about all medications, vitamins, and supplements they are currently taking, as hydroxychloroquine may interact with certain drugs.

Hydroxychloroquine may not prevent malaria in all cases. If a patient experiences fever or other symptoms of illness, they should seek medical help immediately, especially while in a malarious area and for 2 months after returning from the area, as they may need a different medication.

Patients should also avoid exposure to mosquitoes to further reduce the risk of contracting malaria.

Dosing and Administration of Hydroxychloroquine

The dosage and administration of hydroxychloroquine may vary depending on the patient’s medical condition and response to treatment. Patients should take the medication exactly as prescribed by their doctor and should not stop taking it without consulting their doctor, especially if it is being used for malaria prevention or treatment.

It is important for patients to continue taking the medication for the full length of time prescribed, as stopping prevention or treatment too soon may lead to infection or a return of the infection.

Conclusion

Hydroxychloroquine is a versatile medication used to prevent and treat malaria, as well as manage certain autoimmune disorders like lupus and rheumatoid arthritis. While generally well-tolerated, it can have serious side effects and interactions, so patients should closely follow their doctor’s instructions and report any concerning symptoms immediately.

Hydroxychloroquine Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Hydroxychloroquine is used to prevent or treat malaria caused by mosquito bites. The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs.This medication is also used to treat certain auto-immune diseases (lupus, rheumatoid arthritis). It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis.Hydroxychloroquine is not recommended for coronavirus infection, also known as COVID-19, unless you are enrolled in a study. Talk to your doctor about the risks and benefits.

How to use Hydroxychloroquine SULFATE

Take this medication by mouth exactly as directed by your doctor. To help prevent stomach upset, take it with food or milk. Swallow the tablets whole since breaking or crushing them may leave a bitter taste. The dosage and length of treatment are based on your medical condition and response to treatment. Children’s dose is also based on weight.

To prevent malaria, take this medication by mouth as directed by your doctor, usually once a week on the same day each week. Mark a calendar to help you remember. This drug is usually started 1 to 2 weeks before entering the malarious area. Continue to take it weekly while in the area and for 4 to 8 weeks after leaving the area, or as directed by your doctor. To treat malaria, follow your doctor’s instructions.

For lupus or rheumatoid arthritis, take this medication by mouth as directed by your doctor, usually once or twice daily. Your doctor may gradually increase your dose. Once you have been taking the medication for a while and your condition has improved, your doctor may instruct you to lower your dose until you find the dose that works best with the fewest side effects.

If you are also taking a certain drug for diarrhea (kaolin) or taking antacids (such as magnesium/aluminum hydroxide), take hydroxychloroquine at least 4 hours before or after these products. These products may bind with hydroxychloroquine, preventing your body from fully absorbing it.

Use this medication regularly in order to get the most benefit from it. If you are taking it on a daily schedule, take it at the same time(s) each day. Take this medication exactly as prescribed. Do not stop taking it without talking with your doctor, especially if you are taking it for malaria. It is important to continue taking this for the length of time prescribed. Stopping prevention or treatment too soon may lead to infection or a return of the infection.

Tell your doctor if your condition lasts or gets worse. It may take several weeks or months to see improvement if you are taking this for lupus or arthritis. Hydroxychloroquine may not prevent malaria in all cases. If you experience fever or other symptoms of illness, get medical help right away (especially while in the malarious area and for 2 months after returning from the area). You may need a different medication. Avoid exposure to mosquitoes. (See also Notes section.

Side Effects

Nausea, vomiting, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: slow heartbeat, symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), mental/mood changes (such as anxiety, depression, rare thoughts of suicide, hallucinations), hearing changes (such as ringing in the ears, hearing loss), easy bruising/bleeding, signs of liver disease (such as severe stomach/abdominal pain, yellowing eyes/skin, dark urine), signs of kidney problems (such as change in the amount of urine), muscle weakness, unwanted/uncontrolled movements (including tongue/face twitching), hair loss, hair/skin color changes.

This medication may cause low blood sugar (hypoglycemia). Tell your doctor right away if you develop symptoms of low blood sugar, such as sudden sweating, shaking, hunger, blurred vision, dizziness, or tingling hands/feet. If you have diabetes, be sure to check your blood sugars regularly. Your doctor may need to adjust your diabetes medication.

Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, fast/irregular heartbeat, seizures.

This medication may cause serious eye/vision problems. The risk for these side effects is increased with long-term use of this medication and with taking this medication in high doses. Get medical help right away if you have any symptoms of serious eye problems, including: sensitivity to light, vision changes (such as light flashes/streaks, blurred vision, difficulty reading, missing areas of vision).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking hydroxychloroquine, tell your doctor or pharmacist if you are allergic to it; or to chloroquine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain enzyme problem (glucose-6-phosphate dehydrogenase deficiency-G6PD), vision/eye problems, hearing problems, kidney disease, liver disease, regular alcohol use/abuse, skin problems (such as psoriasis), a certain blood disorder (porphyria), seizures.

If you have diabetes, this product may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet.

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Alcohol can also increase your risk of liver problems while you are taking this drug.

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Hydroxychloroquine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using hydroxychloroquine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/”water pills”) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using hydroxychloroquine safely.

Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fast/irregular heartbeat, fainting, slow/shallow breathing, seizures.

Do not share this medication with others.

Lab and/or medical tests (such as eye exams, reflex tests, liver/kidney function, EKG, complete blood counts) should be done if you are taking hydroxychloroquine for a long time. Keep all medical and lab appointments. Consult your doctor for more details.

When traveling in an area at risk for malaria, use protective clothing, insect repellent, and bed nets. Remain indoors or in well-screened areas when possible. If you are taking this medication to prevent or treat malaria, use it for your current travel or condition only. Do not use it later to prevent or treat another infection unless your doctor tells you to.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from moisture and light. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.