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Inflammation of the brain is called. Encephalitis: Symptoms, Causes, and Treatment of Brain Inflammation

What are the symptoms of encephalitis. How is encephalitis diagnosed. What causes encephalitis. How is encephalitis treated. Can encephalitis be prevented. What are the long-term effects of encephalitis. How does encephalitis impact quality of life.

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Understanding Encephalitis: A Serious Brain Inflammation

Encephalitis is a rare but potentially life-threatening condition characterized by inflammation of the brain tissue. This serious neurological disorder can affect individuals of any age, though the very young and elderly are particularly vulnerable. The condition requires immediate medical attention and hospitalization due to its severity and potential for long-term complications.

What exactly is encephalitis?

Encephalitis refers to the inflammation of the brain parenchyma, often accompanied by inflammation of the meninges (meningoencephalitis). This swelling can disrupt normal brain function, leading to a range of neurological symptoms that can vary in severity from mild to life-threatening.

Recognizing the Signs and Symptoms of Encephalitis

The onset of encephalitis can be subtle, often mimicking flu-like symptoms initially. However, the condition can rapidly progress to more severe manifestations. Early recognition of symptoms is crucial for timely intervention and improved outcomes.

What are the initial symptoms of encephalitis?

In its early stages, encephalitis may present with:

  • High fever
  • Severe headache
  • Fatigue
  • Muscle aches
  • Nausea and vomiting

How do symptoms progress as encephalitis worsens?

As the condition advances, more serious neurological symptoms may develop, including:

  • Confusion and disorientation
  • Seizures or convulsions
  • Personality changes and behavioral abnormalities
  • Speech difficulties
  • Weakness or paralysis in certain body parts
  • Loss of consciousness or coma

It’s important to seek immediate medical attention if these symptoms occur, as they can indicate a medical emergency.

Unraveling the Causes of Encephalitis

The etiology of encephalitis can be diverse, with various factors potentially triggering brain inflammation. Understanding these causes is crucial for proper diagnosis and treatment.

Are viruses the primary cause of encephalitis?

Yes, viral infections are the most common cause of encephalitis. Some viruses that can lead to encephalitis include:

  • Herpes simplex virus (HSV-1 and HSV-2)
  • Varicella-zoster virus (causing chickenpox and shingles)
  • Enteroviruses
  • Arboviruses (transmitted by mosquitoes and ticks)
  • Rabies virus

In rare cases, encephalitis can also be caused by bacterial or fungal infections.

Can the immune system cause encephalitis?

Indeed, autoimmune encephalitis can occur when the body’s immune system mistakenly attacks healthy brain tissue. This type of encephalitis is not caused by an infection but by an abnormal immune response. Certain conditions, such as lupus or multiple sclerosis, can increase the risk of autoimmune encephalitis.

Diagnosing Encephalitis: A Multi-Faceted Approach

Prompt and accurate diagnosis of encephalitis is crucial for initiating appropriate treatment and preventing complications. Healthcare providers employ various diagnostic tools and techniques to confirm the presence of brain inflammation and identify its underlying cause.

How do doctors diagnose encephalitis?

The diagnostic process for encephalitis typically involves:

  1. Medical history and physical examination
  2. Neurological assessment
  3. Blood tests to check for signs of infection or inflammation
  4. Cerebrospinal fluid (CSF) analysis through lumbar puncture
  5. Brain imaging studies such as MRI or CT scans
  6. Electroencephalogram (EEG) to assess brain electrical activity
  7. In some cases, brain biopsy may be necessary

These tests help clinicians confirm the diagnosis and determine the most appropriate treatment approach.

Treatment Strategies for Encephalitis

Treatment of encephalitis focuses on addressing the underlying cause, managing symptoms, and preventing complications. The specific treatment plan depends on the type and severity of encephalitis.

What are the primary treatment options for viral encephalitis?

Treatment for viral encephalitis may include:

  • Antiviral medications (e.g., acyclovir for herpes simplex encephalitis)
  • Corticosteroids to reduce brain inflammation
  • Anticonvulsant medications to control seizures
  • Pain relievers and antipyretics to manage fever and discomfort
  • Supportive care, including intravenous fluids and respiratory support if needed

In cases of autoimmune encephalitis, immunosuppressive therapies may be necessary to modulate the immune response.

How long does treatment for encephalitis typically last?

The duration of treatment can vary significantly depending on the severity of the condition and the patient’s response to therapy. Some patients may require only a few days of hospitalization, while others might need several weeks or even months of intensive care and rehabilitation.

Long-Term Consequences and Recovery from Encephalitis

While some individuals recover fully from encephalitis, others may face long-term challenges due to brain damage caused by the inflammation. The recovery process can be lengthy and may require ongoing support and rehabilitation.

What are the potential long-term effects of encephalitis?

Long-term complications of encephalitis may include:

  • Memory problems and cognitive impairment
  • Persistent fatigue
  • Mood disorders and personality changes
  • Epilepsy or recurrent seizures
  • Speech and language difficulties
  • Motor control issues
  • Vision or hearing impairments

The severity and nature of these complications can vary widely among individuals.

How can rehabilitation help in recovery from encephalitis?

Rehabilitation plays a crucial role in the recovery process for many encephalitis survivors. A comprehensive rehabilitation program may include:

  1. Physical therapy to improve mobility and strength
  2. Occupational therapy to regain independence in daily activities
  3. Speech and language therapy for communication difficulties
  4. Cognitive rehabilitation to address memory and thinking problems
  5. Psychological support to manage emotional and behavioral changes

The goal of rehabilitation is to maximize functional recovery and improve quality of life for those affected by encephalitis.

Preventing Encephalitis: Vaccination and Risk Reduction

While not all cases of encephalitis can be prevented, certain measures can reduce the risk of developing this serious condition. Vaccination plays a key role in prevention, especially for certain types of viral encephalitis.

Which vaccines can help prevent encephalitis?

Several vaccines are available that can help prevent some forms of encephalitis:

  • MMR (Measles, Mumps, Rubella) vaccine
  • Japanese encephalitis vaccine
  • Tick-borne encephalitis vaccine
  • Rabies vaccine

These vaccines are particularly important for individuals traveling to areas where certain types of encephalitis are endemic.

Are there other ways to reduce the risk of encephalitis?

In addition to vaccination, other preventive measures include:

  • Practicing good hygiene to prevent viral infections
  • Using insect repellents and protective clothing to avoid mosquito and tick bites
  • Avoiding close contact with animals in areas where rabies is prevalent
  • Seeking prompt medical attention for any suspected infections or neurological symptoms

These precautions can help minimize the risk of developing encephalitis, especially in high-risk areas or situations.

Living with Encephalitis: Support and Quality of Life

For many individuals who have experienced encephalitis, the journey to recovery extends far beyond the acute phase of illness. Adapting to life after encephalitis often requires ongoing support, both medical and emotional.

How does encephalitis impact daily life?

The impact of encephalitis on daily life can be profound and varies from person to person. Some individuals may experience:

  • Difficulties returning to work or school
  • Challenges in maintaining relationships
  • Ongoing medical appointments and therapies
  • Need for assistive devices or home modifications
  • Emotional struggles, including depression and anxiety

Adapting to these changes often requires patience, support, and a multidisciplinary approach to care.

What support is available for encephalitis survivors and their families?

Various resources and support systems are available to help individuals and families affected by encephalitis:

  1. Support groups and peer networks
  2. Patient advocacy organizations
  3. Neuropsychological counseling
  4. Vocational rehabilitation services
  5. Social services and disability support
  6. Educational resources and workshops

These support systems can provide valuable information, emotional support, and practical assistance in navigating life after encephalitis.

Encephalitis is a complex and challenging condition that can have far-reaching effects on individuals and their families. While it can be a life-altering diagnosis, advances in medical care and support systems offer hope for improved outcomes and quality of life. Early recognition of symptoms, prompt medical intervention, and comprehensive follow-up care are crucial in managing this serious neurological condition. As research continues to enhance our understanding of encephalitis, new treatment options and preventive strategies may emerge, offering further hope for those affected by this condition.

Encephalitis – NHS

Encephalitis is an uncommon but serious condition in which the brain becomes inflamed (swollen).

It can be life threatening and requires urgent treatment in hospital.

Anyone can be affected, but the very young and very old are most at risk.

Symptoms of encephalitis

Encephalitis usually starts off with flu-like symptoms, such as a high temperature and headache.

More serious symptoms come on over hours, days or weeks, including:

  • confusion or disorientation
  • seizures or fits
  • changes in personality and behaviour
  • difficulty speaking
  • weakness or loss of movement in some parts of the body
  • loss of consciousness

Dial 999 for an ambulance immediately if you or someone else has these serious symptoms.

Causes of encephalitis

It’s not always clear what causes encephalitis, but it can be caused by:

  • viral infections – very rarely, encephalitis may be caused by the common viruses that causes cold sores (herpes simplex) or chickenpox (herpes varicella) spreading to the brain
  • a problem with the immune system, the body’s defence against infection – sometimes something goes wrong with the immune system and it mistakenly attacks the brain, causing it to become inflamed
  • bacterial or fungal infections – these are much rarer causes of encephalitis than viral infections

Some types of encephalitis are spread by mosquitoes (such as Japanese encephalitis), ticks (such as tick-borne encephalitis) and mammals (such as rabies).

You cannot catch encephalitis from someone else.

Treatments for encephalitis

Encephalitis needs to be treated in a hospital. The earlier treatment is started, the more successful it’s likely to be.

Treatment depends on the underlying cause, but may include:

  • antiviral medicines
  • steroid injections
  • treatments to help control the immune system
  • antibiotics or antifungal medicines
  • painkillers to reduce discomfort or a high temperature
  • medicine to control seizures or fits
  • support with breathing, such as oxygen through a face mask or a breathing machine (ventilator)

How long someone with encephalitis needs to stay in hospital can range from a few days to several weeks or even months.

Recovering from encephalitis

Some people eventually make a full recovery from encephalitis, although this can be a long and frustrating process.

Many people never make a full recovery and are left with long-term problems caused by damage to their brain.

Common complications include:

  • memory loss (amnesia)
  • frequent seizures or fits
  • personality and behavioural changes
  • problems with attention, concentration, planning and problem solving
  • persistent tiredness

These problems can have a significant impact on the life of the affected person, as well as their family and friends.

But help and support is available.

Preventing encephalitis

It’s not always possible to prevent encephalitis, but some of the infections that cause it can be prevented with vaccinations.

These include the:

  • measles, mumps and rubella (MMR) vaccine – a routine vaccination offered to all children in England
  • Japanese encephalitis vaccine – recommended for travellers to at-risk areas, such as parts of Asia
  • tick-borne encephalitis vaccine – recommended for travellers to certain parts of Europe (but not the UK) and Asia
  • rabies vaccination – recommended for travellers to at-risk where access to medical care is likely to be limited. Find out about rabies risks in terrestrial animals by country on GOV.UK.

Speak to a GP surgery if you’re not sure whether your vaccinations are up to date, or you’re planning to travel abroad and do not know if you need any vaccinations.

Page last reviewed: 15 May 2023
Next review due: 15 May 2026

Viral encephalitis – Better Health Channel

Summary

Read the full fact sheet

  • Viral encephalitis is an inflammation of the brain caused by a virus.
  • The most serious potential complication is permanent brain damage. 
  • Children aged under one year and adults aged over 55 years are at increased risk of life-threatening complications.
  • Treatment options include medication to relieve the symptoms and antiviral medications if appropriate.

What is viral encephalitis?

Viral encephalitis is an inflammation of the brain caused by a virus. Some viral diseases, such as measles and rubella, can also progress to involve inflammation of the brain. Other micro-organisms, such as bacteria, fungi and parasites, are capable of triggering encephalitis, but viruses – particularly the group known as enteroviruses – are the leading cause.

Once inside the blood, the viruses migrate to the brain where they start to multiply. The body notices the invasion and mounts an immune system response. This causes the brain to swell. The combination of infection and immune response creates the typical symptoms of viral encephalitis.

The most serious potential complication from viral encephalitis is permanent brain damage. Children aged under one year and adults aged over 55 years are more vulnerable to life-threatening complications.

Symptoms of viral encephalitis

The symptoms of viral encephalitis include:

  • high temperature
  • headache
  • sensitivity to light (photophobia)
  • general malaise
  • stiff neck
  • stiff back
  • vomiting
  • changes to personality
  • confusion
  • memory loss (amnesia)
  • seizures
  • paralysis
  • coma.

Viruses that can cause encephalitis

Some of the viruses that are capable of causing encephalitis include:

  • enteroviruses – such as coxsackievirus, poliovirus and echovirus
  • herpes simplex virus
  • varicella zoster virus
  • Epstein-Barr virus
  • cytomegalovirus
  • adenovirus
  • rubella
  • measles
  • Murray Valley encephalitis (MVE) virus and Kunjin virus
  • Japanese encephalitis virus.

Modes of transmission of viruses

Viruses spread by different means, and some are more infectious than others. Some of the modes of viral transmission include:

  • coughs or sneezes from an infected person that release airborne viruses, which are then inhaled by others
  • infected insects (such as mosquitoes or ticks) and animals, which can transfer some viruses directly into the bloodstream via their bite
  • eating contaminated food or drink
  • the transfer of some viruses can occur through touching an infected person
  • there is evidence to suggest that some cases of viral encephalitis are caused by a dormant viral infection (such as herpes simplex virus) becoming active again.

Infection and the immune system response

Once viruses have gained access to the bloodstream, they can multiply and spread to other parts of the body, including to the spinal cord and brain (the central nervous system). Access to the brain is by blood or nerves. After breaching the blood–brain barrier, the viruses slip inside brain cells. This disrupts, damages and ultimately ruptures the infected brain cells.

Certain viruses have a preference for different areas of the brain. For example, the herpes simplex virus likes to target the temporal lobes located near each ear.

The cells of the immune system rush to the brain and start attacking the viruses. This causes the characteristic brain swelling (cerebral oedema). Both the infection and the attempts of the body to fight the infection are responsible for the symptoms of viral encephalitis.

Complications of viral encephalitis

Babies, older people and people with reduced immunity are at increased risk of developing complications of viral encephalitis. Some of these complications include:

  • low blood pressure (hypotension)
  • low oxygen levels in the blood (hypoxaemia)
  • bleeding inside the brain (intracerebral haemorrhage)
  • permanent brain damage
  • death.

Diagnosis of viral encephalitis

Viral encephalitis is diagnosed using a number of tests including:

  • physical examination
  • blood tests
  • laboratory examination of cerebrospinal fluid (clear liquid that bathes the brain and spinal cord) removed via a lumbar puncture (a procedure in which a small needle is inserted into the lower part of the spine)
  • computed tomography (CT) scan
  • electroencephalography (EEG) to measure brain waves
  • magnetic resonance imaging (MRI).

Treatment for viral encephalitis

Unlike bacteria, viruses are difficult to treat. Antiviral medications only work on a limited number of viruses. Treatment aims to reduce the severity of the symptoms and may include:

  • hospitalisation
  • antiviral medication, given intravenously, if the virus is known to be susceptible to treatment with antiviral medication (such as the herpes simplex virus)
  • intravenous administration of medications to help reduce brain swelling
  • pain-relieving medication
  • medication to prevent vomiting
  • medication to prevent seizures (anticonvulsant)
  • medication to reduce fever, such as paracetamol
  • fluids to prevent dehydration, but not too much as this can worsen cerebral oedema (swelling of the brain).

Long-term outlook for viral encephalitis

The severity of viral encephalitis depends on the particular virus and how quickly treatment was given. Generally, the acute phase of the illness lasts around one or 2 weeks, and the symptoms either disappear quickly or subside slowly over a period of time.

In many cases, the person makes a full recovery. In other cases, the person can be left with varying degrees of brain damage, which may require long-term supportive care and therapy.

Where to get help

  • Always call an ambulance in an emergency (triple zero) Tel. 000
  • Emergency department of your nearest hospital
  • Your GP (doctor)
  • NURSE-ON-CALL Tel. 1300 60 60 24 (24 hours, 7 days) – for confidential health advice from a registered nurse

  • EncephalitisExternal Link, 2017, Medscape, USA.

This page has been produced in consultation with and approved
by:

Department of Health – Public Health – Communicable Disease Prevention and Control

Inflammation of the meninges – diagnosis and treatment at 100med

What kind of disease is this

Meningitis is often referred to as inflammation of the meninges. In the event of its occurrence, the protective layers of the spinal cord and brain become inflamed. This occurs under the influence of simple microorganisms, bacteria, fungal or viral infections. In some cases, the cause of inflammation can be medication or an injury.

Symptoms

Symptoms of inflammation of the meninges:

  • increase in body temperature;

  • the occurrence of hearing problems;

  • significant headaches;

  • nausea;

  • loss of consciousness;

  • vomit;

  • the appearance of a rash on the skin;

  • neck stiffness;

  • drowsiness;

  • convulsions;

  • mental problems, including apathy, hallucinations, anxiety, agitation and other types.

Causes

Causes of inflammation of the meninges:

  • influence of the simplest microorganisms;

  • the presence of fungal infections;

  • bacterial types of infections;

  • viral diseases;

  • a combination of several types of pathogens.

Diagnostics

Diagnosis of inflammation of the meninges is carried out as follows:

  • general, PCR and biochemical blood tests;

  • neurological examination;

  • electroencephalography;

  • puncture of the cerebrospinal type;

  • CT study.

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Our expert’s opinion

Meningitis occurs in acute, fulminant and chronic forms, so only with the right approach can a correct and timely diagnosis be made. Such a complex disease requires complex treatment and high professionalism of medical personnel.

Treatment

Therapy of inflammation of the meninges is carried out in the complex:

  • the use of antiviral agents;

  • the appointment of antipyretics;

  • the use of painkillers;

  • antifungal treatment;

  • antibacterial therapy.

Also during the treatment of meningitis, it is important to maintain the body’s water balance and adhere to the diet recommended by the specialist.

Prevention

Prevention and treatment of inflammation of the meninges includes vaccination recommended for children, patients with immunodeficiency and persons in contact with carriers of the disease. Also, to prevent illness, it is important to maintain a healthy lifestyle, regularly visit the fresh air, exercise, temper and avoid sources of infection. A balanced diet and the use of vitamin and mineral complexes can be a significant step in the prevention of inflammation of the meninges.

Neurologist, reflexologist, kinesiotherapist, PhD

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Neurologist, pediatric neurologist

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Neurologist, cephalologist

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Treatment of inflammation of the brain or spinal cord (meningitis, encephalitis, myelitis)

Treatment of inflammation of the brain or spinal cord (meningitis, encephalitis, myelitis)

Myelitis is a general term for diseases and any inflammatory processes affecting the human spinal cord. Encephalitis is a group of diseases characterized by inflammation of the brain. In turn, meningitis is an infectious disease that affects the membranes of both the spinal cord and the brain.

Causes of inflammation

Encephalitis is caused by neurotropic viruses. The disease can also occur due to complications of rubella, smallpox and measles, and infection can also occur through ticks or mosquitoes. Meningitis is caused mainly by three types of bacteria – pneumococci, meningococci and Haemophilus influenzae. Thus, the cause of inflammation of the spinal cord or brain one way or another are infections of a viral, fungal or bacterial nature, or parasites.

Symptoms

The clinical picture is determined by the general extent and severity of the lesion. In most cases, patients experience the following symptoms:

  • headache
  • rise in body temperature
  • nausea
  • sensitivity to light
  • general weakness
  • in extreme manifestations, paralysis, epileptic seizures, impaired consciousness, etc. are possible.

Diagnosis

To diagnose and start treatment of inflammation of the spinal cord or brain, it is necessary to be examined by a neurologist. In addition to the examination, additional studies are carried out, including:

  • computed tomography of the spinal cord and/or brain
  • magnetic resonance imaging
  • lumbar puncture for cerebrospinal fluid analysis, etc.

Treatment of inflammation of the brain or spinal cord

In such diseases, the doctors of the Viva Clinic prescribe mainly drug therapy. As an additional treatment for inflammation of the brain and spinal cord, physiotherapy exercises, physiotherapy, and massage sessions are indicated.

Drug therapy involves taking antibiotics, vitamins, antiseptics, and other drugs. In addition, to ensure the effectiveness of the treatment of inflammation of the spinal cord and brain, an important role is played by:

  • proper nutrition
  • bed rest
  • competent rehabilitation after recovery

Neurologists

Departments where the procedure is performed

  • Clinic at Vinogradarepr.