Inflammation of the brain is called. Encephalitis: Symptoms, Causes, and Treatment of Brain Inflammation
What are the symptoms of encephalitis. How is encephalitis diagnosed. What causes encephalitis. How is encephalitis treated. Can encephalitis be prevented. What are the long-term effects of encephalitis. Who is at risk for encephalitis.
Understanding Encephalitis: A Serious Brain Inflammation
Encephalitis is a rare but potentially life-threatening condition characterized by inflammation of the brain tissue. This serious neurological disorder can affect people of all ages, but the very young and elderly are particularly vulnerable. Prompt recognition and treatment are crucial for improving outcomes and minimizing long-term complications.
What exactly is encephalitis?
Encephalitis refers to the swelling or inflammation of the brain, typically caused by an infection or an abnormal immune response. This inflammation can disrupt normal brain function and lead to a wide range of neurological symptoms. The severity of encephalitis can vary from mild cases that resolve on their own to severe instances requiring intensive medical intervention.
Recognizing the Symptoms of Encephalitis
The symptoms of encephalitis often develop rapidly and can be mistaken for other conditions. It’s important to be aware of the signs and seek immediate medical attention if encephalitis is suspected.
What are the initial symptoms of encephalitis?
Encephalitis typically begins with flu-like symptoms, including:
- High fever
- Severe headache
- Fatigue
- Muscle aches
- Nausea and vomiting
What are the more serious symptoms that may develop?
As the condition progresses, more severe neurological symptoms can appear, such as:
- Confusion or disorientation
- Seizures or fits
- Changes in personality and behavior
- Difficulty speaking or forming coherent sentences
- Weakness or paralysis in certain parts of the body
- Loss of consciousness
If you or someone you know experiences these serious symptoms, it’s crucial to call emergency services immediately. Prompt medical intervention can be life-saving in cases of encephalitis.
Unraveling the Causes of Encephalitis
Encephalitis can result from various factors, though viral infections are the most common culprits. Understanding the potential causes can help in prevention and early detection.
What are the primary causes of encephalitis?
The main causes of encephalitis include:
- Viral infections: Most commonly, viruses such as herpes simplex (which causes cold sores) or varicella-zoster (responsible for chickenpox) can spread to the brain.
- Autoimmune reactions: In some cases, the body’s immune system may mistakenly attack brain tissue, leading to inflammation.
- Bacterial or fungal infections: Though less common, these can also cause encephalitis in rare instances.
Are there specific types of encephalitis related to environmental factors?
Yes, certain forms of encephalitis are associated with specific environmental factors:
- Japanese encephalitis: Transmitted by mosquitoes, primarily in parts of Asia
- Tick-borne encephalitis: Spread by ticks in certain regions of Europe and Asia
- Rabies encephalitis: Caused by the rabies virus, typically transmitted through mammal bites
It’s important to note that encephalitis itself is not contagious from person to person. However, the viruses that can lead to encephalitis may be transmissible in some cases.
Diagnosing Encephalitis: A Multi-Faceted Approach
Accurate diagnosis of encephalitis is crucial for appropriate treatment. Doctors employ various methods to confirm the condition and identify its underlying cause.
What diagnostic tools are used to identify encephalitis?
The diagnostic process for encephalitis typically involves:
- Physical examination and medical history review
- Neurological tests to assess brain function
- Brain imaging studies such as MRI or CT scans
- Lumbar puncture (spinal tap) to analyze cerebrospinal fluid
- Blood tests to check for infections or autoimmune markers
- Electroencephalogram (EEG) to measure brain electrical activity
Why is rapid diagnosis important in cases of encephalitis?
Swift diagnosis is critical because encephalitis can progress quickly and cause severe brain damage. Early identification allows for prompt initiation of treatment, which can significantly improve outcomes and reduce the risk of long-term complications.
Treatment Strategies for Encephalitis
Treatment for encephalitis requires hospitalization and a multi-faceted approach tailored to the individual case. The primary goals are to address the underlying cause, manage symptoms, and prevent complications.
What are the main components of encephalitis treatment?
The treatment regimen for encephalitis may include:
- Antiviral medications: For cases caused by viral infections, such as acyclovir for herpes simplex encephalitis
- Corticosteroids: To reduce brain inflammation and swelling
- Immunomodulatory therapies: For autoimmune-related encephalitis
- Antibiotics or antifungal drugs: If bacterial or fungal infections are suspected
- Anticonvulsant medications: To control seizures
- Supportive care: Including pain management, fever reduction, and assistance with breathing if necessary
How long does treatment for encephalitis typically last?
The duration of hospital stay for encephalitis can vary widely, ranging from a few days to several weeks or even months. The length of treatment depends on the severity of the condition, the patient’s response to therapy, and the presence of any complications.
Long-Term Effects and Recovery from Encephalitis
While some individuals fully recover from encephalitis, many face long-term challenges due to brain damage sustained during the illness. Understanding these potential outcomes is crucial for patients and their families.
What are some common long-term effects of encephalitis?
Long-term complications of encephalitis may include:
- Memory problems or amnesia
- Recurrent seizures or epilepsy
- Personality and behavioral changes
- Cognitive difficulties, including problems with attention, concentration, and problem-solving
- Chronic fatigue
- Physical disabilities, such as weakness or paralysis
- Speech and language impairments
What does the recovery process from encephalitis involve?
Recovery from encephalitis is often a gradual and challenging process. It may involve:
- Rehabilitation therapies, including physical, occupational, and speech therapy
- Cognitive rehabilitation to address memory and thinking skills
- Psychological support to manage emotional and behavioral changes
- Ongoing medical care to manage any persistent symptoms or complications
- Support from family, friends, and patient support groups
The recovery timeline varies greatly among individuals, with some experiencing significant improvements over months or years, while others may have permanent impairments.
Prevention Strategies for Encephalitis
While not all cases of encephalitis can be prevented, there are measures that can reduce the risk of certain types of the condition.
What vaccinations can help prevent encephalitis?
Several vaccines can protect against viruses that may lead to encephalitis:
- Measles, Mumps, and Rubella (MMR) vaccine
- Japanese encephalitis vaccine for travelers to endemic areas
- Tick-borne encephalitis vaccine for those visiting affected regions
- Rabies vaccination for high-risk individuals or travelers to endemic areas
What other preventive measures can reduce the risk of encephalitis?
Additional prevention strategies include:
- Practicing good hygiene, such as regular handwashing
- Using insect repellents and protective clothing in areas with mosquito-borne diseases
- Avoiding tick bites by wearing long sleeves and pants in wooded areas
- Seeking prompt medical attention for any animal bites, especially in regions where rabies is prevalent
- Maintaining a strong immune system through a healthy lifestyle
While these measures can help reduce the risk, it’s important to remember that some forms of encephalitis may still occur despite precautions.
Special Considerations for High-Risk Groups
Certain populations are at increased risk for developing severe encephalitis or experiencing complications from the condition. Understanding these risk factors is essential for early detection and management.
Who is most vulnerable to severe encephalitis?
Groups at higher risk for severe encephalitis include:
- Infants and young children
- Adults over 55 years of age
- Individuals with weakened immune systems, such as those with HIV/AIDS or undergoing chemotherapy
- People with certain genetic factors that may predispose them to autoimmune encephalitis
- Travelers to areas where mosquito- or tick-borne encephalitis is endemic
What special precautions should high-risk individuals take?
High-risk individuals should consider the following precautions:
- Ensuring all recommended vaccinations are up to date
- Consulting with a healthcare provider before traveling to areas with increased encephalitis risk
- Taking extra care to avoid insect bites and potential exposures to infectious agents
- Seeking medical attention promptly for any signs of infection or neurological symptoms
- Working closely with healthcare providers to manage any underlying conditions that may increase vulnerability
By taking these precautions and maintaining vigilance, high-risk individuals can reduce their chances of developing severe encephalitis and improve their overall outcomes if the condition does occur.
Encephalitis – NHS
Encephalitis is an uncommon but serious condition in which the brain becomes inflamed (swollen).
It can be life threatening and requires urgent treatment in hospital.
Anyone can be affected, but the very young and very old are most at risk.
Symptoms of encephalitis
Encephalitis usually starts off with flu-like symptoms, such as a high temperature and headache.
More serious symptoms come on over hours, days or weeks, including:
- confusion or disorientation
- seizures or fits
- changes in personality and behaviour
- difficulty speaking
- weakness or loss of movement in some parts of the body
- loss of consciousness
Dial 999 for an ambulance immediately if you or someone else has these serious symptoms.
Causes of encephalitis
It’s not always clear what causes encephalitis, but it can be caused by:
- viral infections – very rarely, encephalitis may be caused by the common viruses that causes cold sores (herpes simplex) or chickenpox (herpes varicella) spreading to the brain
- a problem with the immune system, the body’s defence against infection – sometimes something goes wrong with the immune system and it mistakenly attacks the brain, causing it to become inflamed
- bacterial or fungal infections – these are much rarer causes of encephalitis than viral infections
Some types of encephalitis are spread by mosquitoes (such as Japanese encephalitis), ticks (such as tick-borne encephalitis) and mammals (such as rabies).
You cannot catch encephalitis from someone else.
Treatments for encephalitis
Encephalitis needs to be treated in a hospital. The earlier treatment is started, the more successful it’s likely to be.
Treatment depends on the underlying cause, but may include:
- antiviral medicines
- steroid injections
- treatments to help control the immune system
- antibiotics or antifungal medicines
- painkillers to reduce discomfort or a high temperature
- medicine to control seizures or fits
- support with breathing, such as oxygen through a face mask or a breathing machine (ventilator)
How long someone with encephalitis needs to stay in hospital can range from a few days to several weeks or even months.
Recovering from encephalitis
Some people eventually make a full recovery from encephalitis, although this can be a long and frustrating process.
Many people never make a full recovery and are left with long-term problems caused by damage to their brain.
Common complications include:
- memory loss (amnesia)
- frequent seizures or fits
- personality and behavioural changes
- problems with attention, concentration, planning and problem solving
- persistent tiredness
These problems can have a significant impact on the life of the affected person, as well as their family and friends.
But help and support is available.
Preventing encephalitis
It’s not always possible to prevent encephalitis, but some of the infections that cause it can be prevented with vaccinations.
These include the:
- measles, mumps and rubella (MMR) vaccine – a routine vaccination offered to all children in England
- Japanese encephalitis vaccine – recommended for travellers to at-risk areas, such as parts of Asia
- tick-borne encephalitis vaccine – recommended for travellers to certain parts of Europe (but not the UK) and Asia
- rabies vaccination – recommended for travellers to at-risk where access to medical care is likely to be limited. Find out about rabies risks in terrestrial animals by country on GOV.UK.
Speak to a GP surgery if you’re not sure whether your vaccinations are up to date, or you’re planning to travel abroad and do not know if you need any vaccinations.
Page last reviewed: 15 May 2023
Next review due: 15 May 2026
Viral encephalitis – Better Health Channel
Summary
Read the full fact sheet
- Viral encephalitis is an inflammation of the brain caused by a virus.
- The most serious potential complication is permanent brain damage.
- Children aged under one year and adults aged over 55 years are at increased risk of life-threatening complications.
- Treatment options include medication to relieve the symptoms and antiviral medications if appropriate.
What is viral encephalitis?
Viral encephalitis is an inflammation of the brain caused by a virus. Some viral diseases, such as measles and rubella, can also progress to involve inflammation of the brain. Other micro-organisms, such as bacteria, fungi and parasites, are capable of triggering encephalitis, but viruses – particularly the group known as enteroviruses – are the leading cause.
Once inside the blood, the viruses migrate to the brain where they start to multiply. The body notices the invasion and mounts an immune system response. This causes the brain to swell. The combination of infection and immune response creates the typical symptoms of viral encephalitis.
The most serious potential complication from viral encephalitis is permanent brain damage. Children aged under one year and adults aged over 55 years are more vulnerable to life-threatening complications.
Symptoms of viral encephalitis
The symptoms of viral encephalitis include:
- high temperature
- headache
- sensitivity to light (photophobia)
- general malaise
- stiff neck
- stiff back
- vomiting
- changes to personality
- confusion
- memory loss (amnesia)
- seizures
- paralysis
- coma.
Viruses that can cause encephalitis
Some of the viruses that are capable of causing encephalitis include:
- enteroviruses – such as coxsackievirus, poliovirus and echovirus
- herpes simplex virus
- varicella zoster virus
- Epstein-Barr virus
- cytomegalovirus
- adenovirus
- rubella
- measles
- Murray Valley encephalitis (MVE) virus and Kunjin virus
- Japanese encephalitis virus.
Modes of transmission of viruses
Viruses spread by different means, and some are more infectious than others. Some of the modes of viral transmission include:
- coughs or sneezes from an infected person that release airborne viruses, which are then inhaled by others
- infected insects (such as mosquitoes or ticks) and animals, which can transfer some viruses directly into the bloodstream via their bite
- eating contaminated food or drink
- the transfer of some viruses can occur through touching an infected person
- there is evidence to suggest that some cases of viral encephalitis are caused by a dormant viral infection (such as herpes simplex virus) becoming active again.
Infection and the immune system response
Once viruses have gained access to the bloodstream, they can multiply and spread to other parts of the body, including to the spinal cord and brain (the central nervous system). Access to the brain is by blood or nerves. After breaching the blood–brain barrier, the viruses slip inside brain cells. This disrupts, damages and ultimately ruptures the infected brain cells.
Certain viruses have a preference for different areas of the brain. For example, the herpes simplex virus likes to target the temporal lobes located near each ear.
The cells of the immune system rush to the brain and start attacking the viruses. This causes the characteristic brain swelling (cerebral oedema). Both the infection and the attempts of the body to fight the infection are responsible for the symptoms of viral encephalitis.
Complications of viral encephalitis
Babies, older people and people with reduced immunity are at increased risk of developing complications of viral encephalitis. Some of these complications include:
- low blood pressure (hypotension)
- low oxygen levels in the blood (hypoxaemia)
- bleeding inside the brain (intracerebral haemorrhage)
- permanent brain damage
- death.
Diagnosis of viral encephalitis
Viral encephalitis is diagnosed using a number of tests including:
- physical examination
- blood tests
- laboratory examination of cerebrospinal fluid (clear liquid that bathes the brain and spinal cord) removed via a lumbar puncture (a procedure in which a small needle is inserted into the lower part of the spine)
- computed tomography (CT) scan
- electroencephalography (EEG) to measure brain waves
- magnetic resonance imaging (MRI).
Treatment for viral encephalitis
Unlike bacteria, viruses are difficult to treat. Antiviral medications only work on a limited number of viruses. Treatment aims to reduce the severity of the symptoms and may include:
- hospitalisation
- antiviral medication, given intravenously, if the virus is known to be susceptible to treatment with antiviral medication (such as the herpes simplex virus)
- intravenous administration of medications to help reduce brain swelling
- pain-relieving medication
- medication to prevent vomiting
- medication to prevent seizures (anticonvulsant)
- medication to reduce fever, such as paracetamol
- fluids to prevent dehydration, but not too much as this can worsen cerebral oedema (swelling of the brain).
Long-term outlook for viral encephalitis
The severity of viral encephalitis depends on the particular virus and how quickly treatment was given. Generally, the acute phase of the illness lasts around one or 2 weeks, and the symptoms either disappear quickly or subside slowly over a period of time.
In many cases, the person makes a full recovery. In other cases, the person can be left with varying degrees of brain damage, which may require long-term supportive care and therapy.
Where to get help
- Always call an ambulance in an emergency (triple zero) Tel. 000
- Emergency department of your nearest hospital
- Your GP (doctor)
- NURSE-ON-CALL Tel. 1300 60 60 24 (24 hours, 7 days) – for confidential health advice from a registered nurse
- EncephalitisExternal Link, 2017, Medscape, USA.
This page has been produced in consultation with and approved
by:
Department of Health – Public Health – Communicable Disease Prevention and Control
Inflammation of the meninges – diagnosis and treatment at 100med
What kind of disease is this
Meningitis is often referred to as inflammation of the meninges. In the event of its occurrence, the protective layers of the spinal cord and brain become inflamed. This occurs under the influence of simple microorganisms, bacteria, fungal or viral infections. In some cases, the cause of inflammation can be medication or an injury.
Symptoms
Symptoms of inflammation of the meninges:
increase in body temperature;
the occurrence of hearing problems;
significant headaches;
nausea;
loss of consciousness;
vomit;
the appearance of a rash on the skin;
neck stiffness;
drowsiness;
convulsions;
mental problems, including apathy, hallucinations, anxiety, agitation and other types.
Causes
Causes of inflammation of the meninges:
influence of the simplest microorganisms;
the presence of fungal infections;
bacterial types of infections;
viral diseases;
a combination of several types of pathogens.
Diagnostics
Diagnosis of inflammation of the meninges is carried out as follows:
general, PCR and biochemical blood tests;
neurological examination;
electroencephalography;
puncture of the cerebrospinal type;
CT study.
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Our expert’s opinion
Meningitis occurs in acute, fulminant and chronic forms, so only with the right approach can a correct and timely diagnosis be made. Such a complex disease requires complex treatment and high professionalism of medical personnel.
Treatment
Therapy of inflammation of the meninges is carried out in the complex:
the use of antiviral agents;
the appointment of antipyretics;
the use of painkillers;
antifungal treatment;
antibacterial therapy.
Also during the treatment of meningitis, it is important to maintain the body’s water balance and adhere to the diet recommended by the specialist.
Prevention
Prevention and treatment of inflammation of the meninges includes vaccination recommended for children, patients with immunodeficiency and persons in contact with carriers of the disease. Also, to prevent illness, it is important to maintain a healthy lifestyle, regularly visit the fresh air, exercise, temper and avoid sources of infection. A balanced diet and the use of vitamin and mineral complexes can be a significant step in the prevention of inflammation of the meninges.
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Treatment of inflammation of the brain or spinal cord (meningitis, encephalitis, myelitis)
Treatment of inflammation of the brain or spinal cord (meningitis, encephalitis, myelitis)
Myelitis is a general term for diseases and any inflammatory processes affecting the human spinal cord. Encephalitis is a group of diseases characterized by inflammation of the brain. In turn, meningitis is an infectious disease that affects the membranes of both the spinal cord and the brain.
Causes of inflammation
Encephalitis is caused by neurotropic viruses. The disease can also occur due to complications of rubella, smallpox and measles, and infection can also occur through ticks or mosquitoes. Meningitis is caused mainly by three types of bacteria – pneumococci, meningococci and Haemophilus influenzae. Thus, the cause of inflammation of the spinal cord or brain one way or another are infections of a viral, fungal or bacterial nature, or parasites.
Symptoms
The clinical picture is determined by the general extent and severity of the lesion. In most cases, patients experience the following symptoms:
- headache
- rise in body temperature
- nausea
- sensitivity to light
- general weakness
- in extreme manifestations, paralysis, epileptic seizures, impaired consciousness, etc.
are possible.
Diagnosis
To diagnose and start treatment of inflammation of the spinal cord or brain, it is necessary to be examined by a neurologist. In addition to the examination, additional studies are carried out, including:
- computed tomography of the spinal cord and/or brain
- magnetic resonance imaging
- lumbar puncture for cerebrospinal fluid analysis, etc.
Treatment of inflammation of the brain or spinal cord
In such diseases, the doctors of the Viva Clinic prescribe mainly drug therapy. As an additional treatment for inflammation of the brain and spinal cord, physiotherapy exercises, physiotherapy, and massage sessions are indicated.
Drug therapy involves taking antibiotics, vitamins, antiseptics, and other drugs. In addition, to ensure the effectiveness of the treatment of inflammation of the spinal cord and brain, an important role is played by:
- proper nutrition
- bed rest
- competent rehabilitation after recovery
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