Can rheumatoid arthritis be fatal. How does RA affect life expectancy. What are the main complications of rheumatoid arthritis. How can RA patients improve their prognosis.

The Impact of Rheumatoid Arthritis on Life Expectancy

Rheumatoid arthritis (RA) is a chronic inflammatory condition that affects millions worldwide. While RA itself is not directly fatal, it can significantly impact a person’s health and longevity. A comprehensive study conducted in Taiwan, involving nearly 30,000 RA patients, revealed an average life expectancy reduction of 4.97 years compared to the general population. However, it’s crucial to understand that with proper management and treatment, many individuals with RA can maintain a life expectancy similar to those without the condition.

Why do some RA patients have a reduced life expectancy? The answer lies in the widespread inflammation caused by RA, which can increase the risk of developing life-threatening complications over time. Factors such as disease progression, age at diagnosis, lifestyle choices, and the presence of other health conditions all play a role in determining an individual’s prognosis.

Seropositive vs. Seronegative RA

It’s important to note that not all RA cases are the same. Individuals with seropositive RA, characterized by the presence of specific antibodies in the blood, face a higher risk of developing severe forms of the disease. They are also more likely to experience physical complications such as rheumatoid nodules and vasculitis, which can further impact their overall health and life expectancy.

Major Complications Associated with Rheumatoid Arthritis

While RA primarily affects the joints, its impact extends far beyond, potentially affecting various organ systems throughout the body. Understanding these complications is crucial for both patients and healthcare providers in managing the disease effectively.

Cardiovascular Complications

Heart disease is one of the most significant concerns for RA patients. The chronic inflammation associated with RA can damage arteries, heart muscles, and surrounding tissues. Pericarditis, inflammation of the heart’s protective sac, is the most common cardiac complication in RA patients, affecting up to 10% of individuals with symptomatic manifestations.

How does RA increase the risk of heart problems? The condition accelerates the development of atherosclerosis, a buildup of plaque in the arteries. In RA patients, this plaque tends to be more unstable, increasing the risk of heart attacks and strokes. Additionally, certain RA medications, such as nonsteroidal anti-inflammatory drugs and corticosteroids, may further elevate cardiovascular risks.

Respiratory Issues

Respiratory problems are another significant concern for individuals with RA. The inflammation can affect the lungs and surrounding tissues, leading to various complications. These may include:

• Interstitial lung disease
• Pleural effusion
• Pulmonary nodules
• Bronchiectasis

Early detection and management of these respiratory complications are crucial in maintaining lung function and overall health in RA patients.

Increased Susceptibility to Infections

RA patients often face an increased risk of infections due to a combination of factors. The disease itself can compromise the immune system, making individuals more vulnerable to various pathogens. Furthermore, many RA medications, particularly immunosuppressants, can further weaken the body’s natural defenses.

What types of infections are RA patients more prone to? Common infections include respiratory tract infections, urinary tract infections, and skin infections. In some cases, these infections can become severe and potentially life-threatening if not addressed promptly.

Factors Influencing RA Prognosis and Life Expectancy

The prognosis for individuals with RA can vary significantly based on several factors. Understanding these variables can help patients and healthcare providers develop more effective management strategies.

Age at Diagnosis

Early diagnosis and treatment initiation play a crucial role in improving outcomes for RA patients. Those diagnosed at a younger age often have a better prognosis, as early intervention can help slow disease progression and prevent irreversible joint damage.

Gender Differences

Gender plays a role in both the prevalence and severity of RA. Females are more likely to develop severe forms of the disease. However, males with RA face a higher risk of cardiovascular complications compared to their female counterparts.

Lifestyle Factors

Certain lifestyle choices can significantly impact the course of RA and overall life expectancy. Smoking, excessive alcohol consumption, and a sedentary lifestyle can exacerbate symptoms and increase the risk of complications. On the other hand, maintaining a healthy diet, regular exercise, and stress management can help improve outcomes.

Advancements in RA Treatment and Their Impact on Prognosis

Recent years have seen significant improvements in RA treatment options, leading to better outcomes and increased life expectancy for many patients. A 2018 study reported a decrease in overall mortality rates among RA patients, attributing this positive trend to enhanced treatment methods.

Disease-Modifying Antirheumatic Drugs (DMARDs)

DMARDs have revolutionized RA treatment by targeting the underlying causes of inflammation. These medications can slow disease progression, reduce joint damage, and improve overall quality of life. Common DMARDs include methotrexate, hydroxychloroquine, and sulfasalazine.

Biologic Therapies

Biologic agents represent a newer class of RA treatments that target specific components of the immune system involved in inflammation. These medications, such as TNF inhibitors and IL-6 inhibitors, have shown remarkable efficacy in managing RA symptoms and preventing long-term complications.

How do biologics improve RA prognosis? By precisely targeting inflammatory pathways, biologics can effectively control disease activity, reduce joint damage, and lower the risk of cardiovascular complications associated with chronic inflammation.

Strategies for Improving Life Expectancy in RA Patients

While RA can present significant challenges, there are several strategies that patients can employ to improve their prognosis and maintain a high quality of life.

Early Diagnosis and Treatment

Seeking medical attention at the first signs of RA symptoms is crucial. Early diagnosis allows for prompt initiation of treatment, which can help prevent irreversible joint damage and reduce the risk of complications.

Regular Monitoring and Follow-up

Consistent medical check-ups and monitoring of disease activity are essential for effective RA management. Regular assessments allow healthcare providers to adjust treatment plans as needed and address any emerging complications promptly.

Adopting a Healthy Lifestyle

Lifestyle modifications can significantly impact RA progression and overall health. Key recommendations include:

• Maintaining a balanced, anti-inflammatory diet
• Engaging in regular, low-impact exercise
• Quitting smoking and limiting alcohol consumption
• Managing stress through relaxation techniques and mindfulness practices
• Getting adequate sleep and rest

The Role of Mental Health in RA Prognosis

The psychological impact of living with a chronic condition like RA should not be underestimated. Mental health plays a crucial role in overall well-being and can significantly influence disease outcomes.

Depression and Anxiety in RA Patients

Studies have shown that RA patients are at an increased risk of developing depression and anxiety. These mental health conditions can negatively impact treatment adherence, pain perception, and overall quality of life.

How can RA patients address mental health concerns? Seeking support from mental health professionals, joining support groups, and practicing stress-reduction techniques can all contribute to better emotional well-being and, consequently, improved RA management.

Emerging Research and Future Directions in RA Treatment

The field of rheumatology is constantly evolving, with ongoing research aimed at improving RA treatment and outcomes. Several promising areas of study hold potential for further enhancing life expectancy and quality of life for RA patients.

Personalized Medicine Approaches

Researchers are exploring ways to tailor RA treatments based on individual patient characteristics, including genetic markers and biomarkers. This personalized approach could lead to more effective treatments with fewer side effects.

Novel Therapeutic Targets

Scientists continue to investigate new pathways involved in RA pathogenesis, potentially leading to the development of innovative therapies. These may include targeting specific cells or molecules involved in the inflammatory process.

Regenerative Medicine

Advancements in regenerative medicine, including stem cell therapy and tissue engineering, hold promise for repairing damaged joints and tissues in RA patients. While still in early stages, these approaches could potentially revolutionize RA treatment in the future.

As research progresses, what can RA patients expect in terms of future treatments? While it’s difficult to predict specific breakthroughs, the overall trend suggests a move towards more targeted, personalized therapies with fewer side effects and greater efficacy in managing RA and its associated complications.

The Importance of Patient Education and Self-Management

Empowering RA patients with knowledge and self-management skills is crucial for improving long-term outcomes and quality of life. Well-informed patients are better equipped to make decisions about their care, adhere to treatment plans, and implement lifestyle changes that can positively impact their prognosis.

Understanding RA and Its Progression

Educating patients about the nature of RA, its potential complications, and the importance of early intervention can lead to better treatment adherence and outcomes. Healthcare providers should strive to provide clear, comprehensive information about the disease and its management.

Self-Management Techniques

Teaching patients practical self-management skills can significantly improve their ability to cope with RA symptoms and maintain their overall health. These techniques may include:

1. Joint protection strategies
2. Energy conservation techniques
3. Pain management methods
4. Proper use of assistive devices
5. Stress management and relaxation techniques

How can RA patients effectively implement self-management strategies? Working closely with healthcare providers, occupational therapists, and physical therapists can help patients develop personalized self-management plans tailored to their specific needs and lifestyle.

Importance of Medication Adherence

Emphasizing the critical role of medication adherence in managing RA and preventing complications is essential. Patients should understand the purpose of each medication, potential side effects, and the importance of taking medications as prescribed.

By fostering a collaborative relationship between patients and healthcare providers, individuals with RA can take a more active role in their care, potentially leading to improved outcomes and a better quality of life.

Can you die from rheumatoid arthritis? Lifespan and outlook

A person cannot die from rheumatoid arthritis (RA). However, RA can increase the risk of developing complications, such as heart disease. Some of these can be life threatening.

RA is a chronic medical condition that involves increased levels of inflammation in tissues throughout the body.

The condition can make a person more likely to develop health complications affecting the heart and lungs. The risk of complications depends on a range of factors, including age, disease progression, and a person’s lifestyle.

There is currently no cure for RA. However, effective treatment can slow down or stop the condition’s progression and help prevent complications. Treatments work best when a person starts them early in the disease progression.

In this article, we look at how RA may affect a person’s lifespan.

A note about sex and gender

Sex and gender exist on spectrums. This article will use the terms “male,” “female,” or both to refer to sex assigned at birth. Click here to learn more.

Was this helpful?

A person cannot die from RA. However, people with RA typically have a slightly reduced life expectancy. A study of almost 30,000 people with RA in Taiwan found that people with the condition have an average life expectancy reduction of 4.97 years.

However, with the correct management, many people with RA can have the same life expectancy as those without it.

People with seropositive RA are at a greater risk of developing severe forms of RA than those with seronegative RA. They also have a higher risk of developing physical complications such as rheumatoid nodules and vasculitis.

Widespread inflammation from RA can increase a person’s risk of developing other life threatening complications.

Share on PinterestThomas Stockhausen/Getty Images

RA causes inflammation throughout the body that, over time, can damage organ tissues. Having RA-related complications can affect a person’s lifespan.

Existing conditions

Findings of a 2017 study indicate that the following are more likely to cause death in people with RA than in the general population:

• cardiovascular disease
• respiratory disease
• infection
• musculoskeletal conditions

People with RA may be more likely to develop infections because of reduced immune system function. Some medications prescribed to treat RA can also increase the risk of infection.

Other risk factors

It is difficult to predict how complications of RA may affect a person’s lifespan. This is because their risk and severity depend on a wide range of factors.

Factors can include:

• RA progression
• sex, with females being more likely to develop severe RA, though males with and without RA have a higher risk of cardiovascular disease
• age at diagnosis, with early diagnosis improving a person’s outlook
• lifestyle factors such as smoking and drinking alcohol

Authors of a 2018 study report that overall mortality rates among people with RA have decreased in recent years. This may be at least partially due to improved treatment methods.

Medications such as disease-modifying antirheumatic drugs (DMARDs) and biologics can reduce the risk of RA-related complications.

Learn more about DMARDs and biologics here.

As RA progresses, long lasting or frequently occurring inflammation in the joints can lead to permanent joint damage. This can affect the cervical spine joints in the neck and may cause nodules to form under the skin.

RA can also increase the risk of certain health conditions. The following sections discuss three main complications: heart disease, respiratory problems, and infection.

Heart disease

RA can cause inflammation and damage to the arteries, the heart muscles, or tissues surrounding the heart.

Pericarditis, which is inflammation of the pericardium (the pouch surrounding the heart) and fluid buildup in this pouch, may be significant factors. Pericarditis is the most common cardiac complication of RA, though people rarely experience symptoms. Fewer than 10% of people with RA have symptomatic pericarditis.

While pericarditis is rarely a serious complication, any symptoms affecting the pericardium can be life threatening.

People with RA are also much more likely to develop atherosclerosis, which is a buildup of plaque in the arteries. In a person with RA, this plaque is more likely to be brittle and break away, leading to a higher risk of heart attack and stroke.

Some RA medications, including nonsteroidal anti-inflammatory drugs and corticosteroids, may also increase the risk of atherosclerosis. Other medications, including JAK inhibitors, can increase the risk of other major cardiac events.

The Arthritis Foundation notes that RA increases the risk of several other heart complications, including:

• a nearly doubled risk of ischemic stroke
• a tripled risk of deep vein thrombosis, which refers to blood clots in the legs
• a more than quadrupled risk of a life threatening pulmonary embolism

Respiratory disease

According to the Arthritis Foundation, beyond complications that affect the joints, people with RA are most likely to experience complications involving the lungs.

RA increases the risk of respiratory issues, such as:

• nodules in the lungs
• pleural effusion
• bronchiectasis
• interstitial lung disease

The rate of interstitial lung disease is eight times higher in people with RA. It occurs when excessive inflammation from an overactive immune system causes scarring in lung tissue. This can make breathing difficult or impossible, and a person could eventually need a lung transplant.

People with RA may also have a higher risk of developing blockages in the small airways of the lungs. Sometimes, RA medications can also cause adverse reactions in the lungs and lung lining.

Infection

People with autoimmune conditions such as RA are more susceptible to potentially serious and even fatal infections.

In people with RA, it is still unclear whether this susceptibility results from the condition or a side effect of RA medications, including biologics and steroids.

Vaccinations, such as the COVID-19, flu, and pneumococcal vaccines, can help prevent some infections associated with RA.

For more advice on COVID-19 prevention and treatment, visit our coronavirus hub.

Was this helpful?

Other complications

Other complications from RA include:

• inflammation in the eye
• osteoporosis
• anemia
• type 2 diabetes
• rheumatoid vasculitis
• lymphoma
• chronic kidney disease
• depression

Learn more about the effects of RA on the body here.

Most people with RA can lead a full and active life. It is important for a person to follow a healthy lifestyle to reduce the risks of other illnesses associated with RA.

There is no cure for RA. Treatments aim to slow the progression of the condition and manage symptoms such as inflammation and pain.

An effective treatment plan can help prevent complications of RA. Some home remedies may also help manage RA symptoms and protect against complications.

Doctors may recommend that people with RA make changes to their diet and lifestyle, such as:

• quitting smoking
• doing regular low impact exercises, such as swimming and light muscle training
• eating a balanced diet and avoiding processed foods
• going to counseling or engaging with a support group
• taking plenty of time to rest throughout the day

People with RA should work directly with a doctor to create and adapt their treatment plan.

Regular appointments with a rheumatologist may also help. The specialist can monitor the progression of the disease and recommend any necessary treatment changes.

Complementary therapies — such as massage, meditation, and acupuncture — may also benefit people with the condition. Results can vary, so it may help to try a few different techniques.

Following an anti-inflammatory diet for RA can also help.

Learn about 11 home remedies for RA here.

RA is a chronic condition with no known cure. People do not die from RA. However, it can lead to serious complications that can compromise overall health.

A person with RA may have a reduced life expectancy. However, the condition affects each person differently, and it can be difficult for doctors to predict an individual’s outlook.

Receiving treatment and making recommended lifestyle changes early on can help manage symptoms and improve a person’s outlook.

A person with RA should work directly with a doctor and rheumatologist to set and modify treatments. Doing this can help manage symptoms and slow the progression of the disease.

Can you die from rheumatoid arthritis? Lifespan and outlook

A person cannot die from rheumatoid arthritis (RA). However, RA can increase the risk of developing complications, such as heart disease. Some of these can be life threatening.

RA is a chronic medical condition that involves increased levels of inflammation in tissues throughout the body.

The condition can make a person more likely to develop health complications affecting the heart and lungs. The risk of complications depends on a range of factors, including age, disease progression, and a person’s lifestyle.

There is currently no cure for RA. However, effective treatment can slow down or stop the condition’s progression and help prevent complications. Treatments work best when a person starts them early in the disease progression.

In this article, we look at how RA may affect a person’s lifespan.

A note about sex and gender

Sex and gender exist on spectrums. This article will use the terms “male,” “female,” or both to refer to sex assigned at birth. Click here to learn more.

Was this helpful?

A person cannot die from RA. However, people with RA typically have a slightly reduced life expectancy. A study of almost 30,000 people with RA in Taiwan found that people with the condition have an average life expectancy reduction of 4.97 years.

However, with the correct management, many people with RA can have the same life expectancy as those without it.

People with seropositive RA are at a greater risk of developing severe forms of RA than those with seronegative RA. They also have a higher risk of developing physical complications such as rheumatoid nodules and vasculitis.

Widespread inflammation from RA can increase a person’s risk of developing other life threatening complications.

Share on PinterestThomas Stockhausen/Getty Images

RA causes inflammation throughout the body that, over time, can damage organ tissues. Having RA-related complications can affect a person’s lifespan.

Existing conditions

Findings of a 2017 study indicate that the following are more likely to cause death in people with RA than in the general population:

• cardiovascular disease
• respiratory disease
• infection
• musculoskeletal conditions

People with RA may be more likely to develop infections because of reduced immune system function. Some medications prescribed to treat RA can also increase the risk of infection.

Other risk factors

It is difficult to predict how complications of RA may affect a person’s lifespan. This is because their risk and severity depend on a wide range of factors.

Factors can include:

• RA progression
• sex, with females being more likely to develop severe RA, though males with and without RA have a higher risk of cardiovascular disease
• age at diagnosis, with early diagnosis improving a person’s outlook
• lifestyle factors such as smoking and drinking alcohol

Authors of a 2018 study report that overall mortality rates among people with RA have decreased in recent years. This may be at least partially due to improved treatment methods.

Medications such as disease-modifying antirheumatic drugs (DMARDs) and biologics can reduce the risk of RA-related complications.

Learn more about DMARDs and biologics here.

As RA progresses, long lasting or frequently occurring inflammation in the joints can lead to permanent joint damage. This can affect the cervical spine joints in the neck and may cause nodules to form under the skin.

RA can also increase the risk of certain health conditions. The following sections discuss three main complications: heart disease, respiratory problems, and infection.

Heart disease

RA can cause inflammation and damage to the arteries, the heart muscles, or tissues surrounding the heart.

Pericarditis, which is inflammation of the pericardium (the pouch surrounding the heart) and fluid buildup in this pouch, may be significant factors. Pericarditis is the most common cardiac complication of RA, though people rarely experience symptoms. Fewer than 10% of people with RA have symptomatic pericarditis.

While pericarditis is rarely a serious complication, any symptoms affecting the pericardium can be life threatening.

People with RA are also much more likely to develop atherosclerosis, which is a buildup of plaque in the arteries. In a person with RA, this plaque is more likely to be brittle and break away, leading to a higher risk of heart attack and stroke.

Some RA medications, including nonsteroidal anti-inflammatory drugs and corticosteroids, may also increase the risk of atherosclerosis. Other medications, including JAK inhibitors, can increase the risk of other major cardiac events.

The Arthritis Foundation notes that RA increases the risk of several other heart complications, including:

• a nearly doubled risk of ischemic stroke
• a tripled risk of deep vein thrombosis, which refers to blood clots in the legs
• a more than quadrupled risk of a life threatening pulmonary embolism

Respiratory disease

According to the Arthritis Foundation, beyond complications that affect the joints, people with RA are most likely to experience complications involving the lungs.

RA increases the risk of respiratory issues, such as:

• nodules in the lungs
• pleural effusion
• bronchiectasis
• interstitial lung disease

The rate of interstitial lung disease is eight times higher in people with RA. It occurs when excessive inflammation from an overactive immune system causes scarring in lung tissue. This can make breathing difficult or impossible, and a person could eventually need a lung transplant.

People with RA may also have a higher risk of developing blockages in the small airways of the lungs. Sometimes, RA medications can also cause adverse reactions in the lungs and lung lining.

Infection

People with autoimmune conditions such as RA are more susceptible to potentially serious and even fatal infections.

In people with RA, it is still unclear whether this susceptibility results from the condition or a side effect of RA medications, including biologics and steroids.

Vaccinations, such as the COVID-19, flu, and pneumococcal vaccines, can help prevent some infections associated with RA.

For more advice on COVID-19 prevention and treatment, visit our coronavirus hub.

Was this helpful?

Other complications

Other complications from RA include:

• inflammation in the eye
• osteoporosis
• anemia
• type 2 diabetes
• rheumatoid vasculitis
• lymphoma
• chronic kidney disease
• depression

Learn more about the effects of RA on the body here.

Most people with RA can lead a full and active life. It is important for a person to follow a healthy lifestyle to reduce the risks of other illnesses associated with RA.

There is no cure for RA. Treatments aim to slow the progression of the condition and manage symptoms such as inflammation and pain.

An effective treatment plan can help prevent complications of RA. Some home remedies may also help manage RA symptoms and protect against complications.

Doctors may recommend that people with RA make changes to their diet and lifestyle, such as:

• quitting smoking
• doing regular low impact exercises, such as swimming and light muscle training
• eating a balanced diet and avoiding processed foods
• going to counseling or engaging with a support group
• taking plenty of time to rest throughout the day

People with RA should work directly with a doctor to create and adapt their treatment plan.

Regular appointments with a rheumatologist may also help. The specialist can monitor the progression of the disease and recommend any necessary treatment changes.

Complementary therapies — such as massage, meditation, and acupuncture — may also benefit people with the condition. Results can vary, so it may help to try a few different techniques.

Following an anti-inflammatory diet for RA can also help.

Learn about 11 home remedies for RA here.

RA is a chronic condition with no known cure. People do not die from RA. However, it can lead to serious complications that can compromise overall health.

A person with RA may have a reduced life expectancy. However, the condition affects each person differently, and it can be difficult for doctors to predict an individual’s outlook.

Receiving treatment and making recommended lifestyle changes early on can help manage symptoms and improve a person’s outlook.

A person with RA should work directly with a doctor and rheumatologist to set and modify treatments. Doing this can help manage symptoms and slow the progression of the disease.

Moscow Exchange introduced a trading terminal for the Russian market

The Trade Radar terminal is designed for various categories of users. Subsequently, its functionality will be expanded and will allow you to make transactions with various assets, as well as process exchange data with high quality

Photo: Mikhail Grebenshchikov / RBC

Moskovskaya
exchange
presented a trading terminal of its own design “Trade Radar” at the St. Petersburg International Economic Forum (SPIEF-2023). In the near future, investors will have access to the beta version, and before the end of the year — to the full version of the product.

During the presentation, the head of the trading platform, Yuri Denisov, said that the product is designed for different categories of users, RBC Investment correspondent reported. The terminal consists of two parts – informational and trading.

Screenshot of the trading terminal of the Moscow Exchange “Trade Radar”

(Photo: Moscow Exchange)

adv. rbc.ru

Informational is based on current real-time quotes, as well as historical data for all trading sections of the Moscow Exchange. In addition, the terminal contains a calendar of events, the news feed of the Prime agency, reference data and data on corporate actions. Analytical tools – visualization, technical analysis – will allow you to process this information.

The trading part allows you to negotiate deals through a secure multimodal chat, which is both built into the system itself and provided as a separate application on mobile devices. Thanks to the trading part, investors will be able to conclude deals on the OTC market, and market makers will be able to track indicative asset prices.

Screenshot of the trading terminal of the Moscow Exchange “Trade Radar”

(Photo: Mosbirzha)

The terminal has the ability to integrate with external systems of post-trading services, information analysis, and trading decision making. The guarantee of security and safety of personal data is provided by the Moscow Exchange, which administers the service.

In the final version, Trade Radar will have a wide range of data processing and visualization functions. “In the future, the terminal will allow Russian and foreign companies in the financial and other sectors, as well as ministries and departments, to receive comprehensive data on the state of the Russian financial market, exchange information, news flows, company reporting, use analytical tools and make trading operations with various assets,” it says. in the site message.

In the spring of 2022, the Bloomberg trading terminal was suspended in Russia and Belarus. “Customers in the two countries will not be able to access any of Bloomberg’s financial products, including the terminal, data license, data feed, and electronic trading platforms,” ​​the agency said in a statement. Also, Russian users do not have access to a product that is a direct competitor to Bloomberg – Eikon from Thompson Reuters.

A regulated market where sellers and buyers meet, trading in various assets: stocks, bonds, currencies, futures, commodities. Everyone can become a participant in trading on the stock exchange – for this you need to open a brokerage account. Each transaction is concluded at a market price, is completed almost instantly, and is also registered and controlled.
Read more

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