Best Drugs for Constipation – Consumer Reports

Based on all the ads for prescription laxatives, you may think that the country is gripped by an epidemic of hard-to-treat constipation. And the Food and Drug Administration seems to think so, too. It has approved five new prescription medications for the problem in the past four years.

But while constipation can be serious and require medical intervention, in many cases lifestyle and diet changes suffice. And when they don’t, prescription drugs are usually not needed, says Arnold Wald, MD, a professor of gastroenterology and hepatology at the University of Wisconsin School of Medicine and Public Health.

While all the new prescription products provide more treatment options, Wald says, most people don’t need them.

Instead, over-the-counter drugs such as polyethylene glycol (Miralax and generic), bisacodyl (Dulcolax laxative tablets and generic), or senna (Ex-Lax, Senokot, and generic) are a far better choice. They tend to work at least as well, often have more evidence for their safety, and are much cheaper.

For example, generic polyethylene glycol costs less than $15 for a month’s supply. Someone without health insurance would have to shell out $500 monthly or more for many of the prescription drugs.

Here’s what you need to know about treating constipation. 

It’s a myth that a daily bowel movement is essential to good health, Wald says. But having fewer than three bowel movements per week, excessive straining, a sense of not being finished, or having hard, lumpy stools are signals you may have constipation.

About 15 percent of Americans suffer from the condition for months and even years, studies show. Women are three times as likely as men to experience constipation, and seniors are also at high risk. 

“Occasional constipation is quite common,” says Brian Lacy, MD, a gastroenterologist at the Mayo Clinic in Jacksonville, Fla., and co-editor in chief of The American Journal of Gastroenterology. “Many patients note a change in their usual bowel habits when they change their daily routine, travel, change their diet (especially if they go on a weight-loss program), or reduce their level of activity.” 

But for some people the condition becomes chronic, with uncomfortable symptoms lasting three months or longer.

Whether you’ve been constipated for days or months, the first steps should be to adjust your diet and habits. 

“Many of us don’t eat a very high-fiber diet,” Wald points out. Dietary fiber from foods such as vegetables, fruits, whole grains, and nuts helps create softer, bulkier stools that pass through your gut more quickly. 

If you can’t get enough fiber in your diet, consider a supplement. Those containing psyllium, such as Metamucil, Konsyl, and generics, may work better than other forms, research suggests. 

Wald also recommends getting more physical activity, which can help get the bowels moving.

When boosting fiber and exercise doesn’t do the trick, it’s reasonable to consider an over-the-counter laxative.  

In general, OTC laxatives work by increasing water content in the stool so that it’s softer and easier to pass, Wald says. All of them are safe and effective for most patients. But you may find that one type works better for you or causes fewer side effects. “Everyone’s colon is a little different,” he says. 

Occasional constipation usually lasts only a few days and will resolve on its own, Lacy says. If you’re really uncomfortable, you can take an OTC laxative until things get back to normal.

For chronic constipation that has gone on for months, Lacy advises giving a drug time to work. “If someone does not improve after four weeks, then I recommend switching to another agent,” he says. In some cases, your doctor may recommend combining different types of medications.

Here’s a summary of the types of laxatives you’ll find on your drugstore shelves:

Polyethylene glycol (MiraLax and generic) works by pulling water into the colon, which softens the stool and stimulates the walls of the intestine to move it along. Its safety and effectiveness make it a first choice for many doctors and patients.

A recent analysis of 41 studies of OTC laxatives published in The American Journal of Gastroenterology found robust evidence that polyethylene glycol works well for chronic constipation while causing minimal side effects. The analysis found that it worked better than prescription laxatives. Lacy recommends taking it after dinner so that it kicks in after your breakfast the next morning. It can take a couple of days before you notice a difference in your bowel movements. 

Stimulant laxatives such as bisacodyl (Dulcolax laxative tablets and generic) and senna (Ex-Lax, Senokot, and generic) trigger rhythmic contractions in the intestinal muscles that push stools through more quickly. That action stimulates sluggish bowels and keeps stools soft as the colon has less time to absorb the moisture. The recent review of OTC drugs found good evidence to recommend senna for chronic constipation and moderate evidence for bisacodyl.

The downside to stimulant laxatives, according to the review, is that they can cause side effects such as abdominal pain and diarrhea. “Because they stimulate the colon, sometimes they can cause spasms or cramps,” Lacy says. “That said, they are effective.” The products generally start to work within 6 to 12 hours. 

Magnesium-based laxatives contain compounds that draw water into the stool, such as magnesium hydroxide (Phillips’ Milk of Magnesia and generic) and magnesium citrate (Citroma and generic.) The American Journal of Gastroenterology review found moderate evidence to support the use of magnesium laxatives for chronic constipation. 

Senna and magnesium-based laxatives were equally effective, according to a randomized clinical trial of 90 people with chronic constipation published in January 2021 in The American Journal of Gastroenterology. Those taking senna were more likely than people taking a magnesium laxative to reduce their dose because of side effects.  

The kidneys help process magnesium. So people with kidney disease should avoid anything other than the occasional use of magnesium-based laxatives to prevent a buildup of dangerously high levels of the mineral in the body.

Stool softeners such as docusate sodium (Colace, Phillips’ Stool Softener, and generic) and docusate calcium alter the surface of the stool, allowing in more water and oil. By making stools easier to pass, these drugs can help in certain situations—after surgery, for example, when you want to avoid straining to have a bowel movement. But research shows that stool softeners aren’t effective for chronic constipation.

Suppository laxatives such as Fleet Glycerin Suppository and Dulcolax Medicated Laxative Suppository usually take effect in less than an hour. They can be helpful for occasional constipation but aren’t intended for everyday use, Wald says.

If you’re still backed up a week after being on OTC laxatives, talk with your healthcare provider, Lacy says. Your doctor may be able to determine an underlying cause for your symptoms. For example, medical conditions such as diabetes or an underactive thyroid can cause constipation, as can many common medications, including certain antacids, antidepressants, antihistamines, blood pressure drugs, pain relievers, and drugs for urinary incontinence. 

Your doctor can also advise you on doses and timing of OTC products to get better results. If none of those approaches work, it’s time to consider a prescription solution. But don’t expect a miracle.

Prescription drugs to treat constipation are relative newcomers to the market. Since 2017 the FDA has approved plecanatide (Trulance), tenapanor (Ibsrela), prucalopride (Motegrity), and lactitol (Pizensy) as well as naldemedine (Symproic) for opioid-induced constipation. 

In addition, prescription drugs cost much more than their OTC counterparts. Without insurance, they cost about $450 to $550 a month, according to GoodRx. And with the exception of some older osmotic laxatives, none of those drugs are available yet as a low-cost generic. So even with insurance, you may be on the hook for a sizable co-pay.

For all those reasons, most people should consider prescription drugs only after OTC remedies haven’t worked. “You don’t go on to those drugs until you’ve failed at what’s cheap and readily available,” Wald says.

Here’s a summary of prescription medications that the FDA has approved for treating chronic constipation: 

Secretory laxatives including linaclotide (Linzess), lubiprostone (Amitiza), and plecanatide (Trulance) work by causing the intestines to secrete more fluid and may also help block abdominal pain. All the drugs in this category are also FDA-approved for treating irritable bowel syndrome with constipation. 

“The worst side effect for all three [available] agents is diarrhea,” Lacy says. About 5 percent of people taking Linzess experience severe diarrhea, research suggests, compared with about 1 to 2 percent with the other drugs in this class. Amitiza is more likely than the other drugs to cause nausea. Nearly 30 percent of people taking the recommended dose of the drug reported feeling nauseous compared with only 3 percent in the placebo group. Taking the drug with food can reduce that side effect, Lacy says. 

Prucalopride (Motegrity) stimulates muscles in the G.I. tract to move things along. Common side effects include abdominal pain, diarrhea, headache, and nausea. Most people experiencing diarrhea or headache reported that the symptoms got better in a few days. In addition, Motegrity carries a warning that it could cause suicidal thoughts or behavior, although the FDA has not conclusively linked the drug to that risk.

Osmotic laxatives such as lactulose (Constulose, Enulose, and generic) work similarly to OTC polyethylene glycol and aren’t necessarily any better than the cheaper drugstore product Wald says.

Few studies have compared constipation medications head-to-head. To get an idea of relative effectiveness, researchers from the U. S. and the U.K. analyzed data from 33 studies comparing a drug with a placebo. Results published online in August 2019 in The Lancet Gastroenterology & Hepatology found that after four weeks, the OTC stimulant laxatives bisacodyl and sodium picosulfate ranked first in effectiveness but last in terms of side effects; after 12 weeks, Motegrity came out on top. 

The choice for which prescription drug to take often comes down to what’s covered under a patient’s health insurance, Lacy says. Due to the warning, some insurers won’t cover prucalopride unless a patient hasn’t responded to one of the secretory laxatives.

Opioid pain relievers such as Vicodin, Percocet, and Oxycontin are known not only for their risk of addiction but also for constipation. Forty to 80 percent of people taking opioids for long-term pain experience constipation, according to the American Gastroenterological Association.

The FDA has approved three drugs specifically for constipation caused by taking prescription opioids for pain: methylnaltrexone (Relistor), naldemedine (Symproic), and naloxegol (Movantik).

These medications, called peripherally acting mu-opioid receptor antagonists or Pamoras, relieve constipation by preventing opioids from attaching to receptors in the intestines. The drugs contain a compound that keeps them from reaching the brain, so they don’t interfere with an opioid’s pain-relieving effects.

But patients with opioid-induced constipation should still try OTC laxatives before considering a prescription drug, according to AGA guidelines published in 2019. “You want to give routine laxatives a chance because many times you can treat the constipation without going to an opioid antagonist,” Wald says. 

As with other prescription constipation drugs, one big drawback of Pamoras is price. The average cash price for a month’s supply of Movantik is $442; Symproic, $474; Relistor tablets, $2,362; and injectable Relistor, a whopping $4,840, according to GoodRx.

If OTC laxatives don’t work, AGA guidelines strongly recommend naldemedine based on high-quality evidence and naloxegol based on moderate-quality evidence that the drug works.

Naldemedine is also the only drug of the three backed by long-term safety data (a year’s worth). The AGA gave methylnaltrexone a conditional recommendation based on a lack of good evidence supporting the drug. The group also noted that it costs far more than other drugs in its class. 

Amitiza is FDA-approved for treating opioid-induced constipation as well as chronic constipation. But the AGA didn’t find enough evidence to make a recommendation for using that or other types of prescription drugs (besides Pamoras) to treat constipation caused by opioids.

Teresa Carr

Teresa Carr is an award-winning journalist with a background in both science and writing, which makes her curious about how the world works and eager to tell you about it. She is a former Consumer Reports editor and 2018 Knight Science Journalism Fellow at MIT and has more than two decades’ experience reporting on science, health, and consumer issues.

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29 People found this comment helpful

I have had trouble with constipation all of my life, I’m 54. And this is the first medication that has worked for me. It doesn’t cramp unless I take too much, so I’ve had to figure out how much is just right. I would highly recommend it to anyone with irritable bowel disease or constipation.

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SORT BY Condition: Incomplete or Infrequent Bowel Movements

Overall rating 3.0

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Welp I got put on this Bc of a hospital stay and it works give it about a day then I have been getting cramps and feeling like I need to go

1

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Overall rating 5.0

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Take it at night before going to bed, by morning I can go to the toilet with no problems. Sometimes I get minimal cramps and a little weakness, but it passes in few minutes. Highly recommended. The only one that works with no side-effects.

6

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I am a male in my early 80’s. Over the years I have had bouts with constipation. About 6 years ago , after trying many drugs I started using senna and have been well satisfied. I take 2 8mg pills twice a day and have 2 or 3 good bowel movements every morning. My stools tend to be loose and movements are very easy.

6

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I suffered from chronic constipation. Senna is the best natural laxative I have tried. Works overnight easily. No harsh smell.

1

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I have been taking Senna Leaf powder or Senna Leaf powder with Docusate Sodium tablets as a laxative for approximately 30 years. Each tablet contains 5mg of Senna and 50mg of Docusate Sodium. My usual dosage is three tablets every second day. Primarily I am using this medication to treat constipation caused by a large Colon. So far I have not had any side effects and dosage has remained fairly consistent. Hope this may help others who may be worried on the long term effects of taking Senna extracts.Read More Read Less

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i am always constipated. i have been for many years. fruit used to work, vegatables used to work. fiber pills and fiber stuff don’t work. i exercise. nothing works. i haven’t talked to my doctor about using senna, but when i go to doctor i always write it down in the appropriate space that asked for medication. doctors haven’t commented about. they know all the medications i take. all the prescribed and non prescribed. senna works, i have been taking it for about 2 years on a daily basis. i had to experiment to find the correct dose. but it works. its the only thing that works other than milk of mag. that i hate. yukRead More Read Less

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I am a throat cancer patient and must consume all food water meds through a G-tube. Use this periodically if I have gone more than 2 days w/o relief. Takes 24 to 48 hours to really kick in but does so gradually and gently w/ no side eddects.

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Gentle on stomach and emptied bowels well took 10 hrs to take effect 7 bowel movements over two days felt lighter after taking this laxative and in a contented mood.

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Senna has worked very well for me. Really no side effects. But it seems I can’t get it anymore and am disappointed inn that.

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I am a kidney transplant patient currently going through rejection. One of my medicines that I need to take with meals gives me occasional constipation. My doctor had recommended this to me because of how effective it was, and was told to take it as needed. After using it for more than 2 weeks, I started to receive severe stomach cramping, to the point where I wouldn’t want to it. 3 weeks after I stopped taking this, the cramps are still here, but not as severe.

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I have had trouble with constipation all of my life, I’m 54. And this is the first medication that has worked for me. It doesn’t cramp unless I take too much, so I’ve had to figure out how much is just right. I would highly recommend it to anyone with irritable bowel disease or constipation.

29

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Carrying pills and congestion

Constipation, or fixed, is called a camp, when a person sticks to hard, rare, or painful, deformities. Dane’s ailment is filled with one of the widest, to which the faces are carried by a great assortment. The reasons for blaming improper defecation can be different. Quite often the problem appears in people who have a vicarious diet with a low level of cellular tissue. Another reason may be a side effect of taking antidepressants or vitamin complexes with high blood pressure. Irritable bowel syndrome and other ailments that affect the intestinal tract can be diagnosed by a doctor in case of constipation.

Carrying, the price of which is in front of you, may be needed in times of hormonal disorders or low activity of the thyroid gland. Nezalezhno vіd dzherela problems first deієyu bude stavlennya to fahivtsya. It is especially important in times of bleeding, pain sensations in the abdomen or numbness. In the Internet pharmacy “Zdravitsa” you will always be asked for the exact service and the weekly prices for the preparations.

Tablets for the prevention and treatment of constipation

For the fight against constipation, medications are prescribed, divided into categories depending on the mechanism of infusion. Stink can booty:

• contacts;
• volitional;
• volume;
• help me’akshyuchimi;
• combinations.

One of the most popular drugs is the carrying capacity of swidka di. Behind the mechanism of injection on the body, such speeches are brought to the point of being arbitrary. The stench allows you to accumulate the motherland in the body, which leads to an increase in the intestines. Yogo walls stick with mechanical teasing, which calls for defecation. If you buy it from a random category, then the effect can be seen in 3-6 years from the moment you receive it.

Swyvidko take pills of a milder type. Carrying the goods of the category zdatnі reduce the hardness of feces, to begin to pass more easily through the intestines. The category includes oils and rare paraffins. You can see the result in 4-5 years. Glycerin suppositories will become relevant solutions, if it is necessary to take the test result. If you need to buy a carry-on, then such a medicine will be inexpensive, and vicorous candles can be grown and children.

Carriage of goods – list

• Duphalac
• Bisacodyl
• Microlax
• Picolax
• Senade
• Fortrans
• Guttalax
• Izidu
• Normolact
• Mucofalk
• Legolax
• Iziklin

I will fix the good help microclysm. It is designed to ensure a mild laxative effect, for which no more than 15 quills will be required. Microclysters can vikoristovuvatisya the least, the shards are not zdatnі lead to teasing the intestines. Before soft carrying drugs, one can see the volume of carrying drugs. The stench leads to a bowel movement to increase bowel obligation. The basis of such preparations includes such components as plantain, visivka and seaweed.

Contact carriers are available in Ukraine. Its effectiveness is related to the stimulation of receptors, which are located in the intestines, which allow to strengthen peristalsis. Like pokhіdnі can vikoristovuvatysya senna or dephenyl. Cream of tablets, which seem to have more medications for constipation, can be combined with granules, rarely carried by other drugs. You can buy carry-on pills directly at once, by ordering from our online pharmacy. We are guaranteed to promptly improve skin healing.

Fasten up to the most unacceptable events, as it is impossible to insure. The problem of the wiccan is that there is too much feces in the intestines, which does not lead to defecation at the same time. Such an illness can lead to a total decrease in the activity of a person, leading to headaches and apparent severity. For effective bowel cleansing, various medicines are used today. By choosing our online pharmacy, the client will have access to the best pharmaceutical products in Ukraine. Having speeded up our site, you can be sure that the choice is correct. Our price is more effective, as it demonstrates preparations for constipation.

How are the pills fixed in the market?

Treatment for illness should be repaired only after a consultation with a doctor. You can only choose the right drug, which in a particular case will give the optimal effect and turn off the negative effects of the drug. You can buy relief for constipation on our website, where you can find offensive medicines:

• Osmotic treatments for constipation. With this help, water will not be absorbed by the walls of the intestines, which will lead to an increase in the pressure and mechanical emptying.
• Preparation to be injected into the receptor system. Here one can see preparations, in the basis of which there is an extract of buckthorn or canopy.
• Relief from constipation with enveloping effect. The intake of such medications allows you to introduce feces more quickly and easily.

Tablets for constipation allow you to get miraculous results when taken in combination. Їх slid to add the right, directing to colonic patency of the intestines, as well as a sparing diet. Dodatkovo varto scoring the upper way of life and promoting the level of physical activity. The drug once fixed is important to start stopping at the first symptoms of the problem. The vitality of the body, as it accumulates, leads to an increase in the level of toxins, which can provoke a hangover and that. Regular constipation is the most common symptom of ailment that affects the intestinal tract.

Efficient ways of fixing

Expanding solutions to stop the funding of traditional medicine to fight the problem. It is necessary to understand that more assistive measures are less likely to cause symptoms to disappear, that problems with defecation in the future should be explained. It is better to win the overturned faces in case of constipation, for the creation of which, serious investigations were carried out.

Leather medicinal preparation for fighting constipation with a set of singing features. Provіvshi diagnostics, likar zumіє choose the best complex and install the trivality of the likuvannya. Constipation can take different forms. So, persistent constipation conveys the need to quickly cleanse the intestines, so as not to cause serious damage to the body. Illness can be viklikana otruennyam or hit by helminths. One of the serious problems is the disappearance of fecal stones. Doctors state that today there are more constipations caused by low activity of people or by taking an unhealthy diet. Change in sleep mode and sleeplessness and a sharp transition to a new diet can also lead to stagnation of feces.

In the Internet pharmacy “Zdravitsa” you can order medicines, as they took away the certificates of quality. We spіvpratsyuєmo only with nadіyni postal workers. Buy faces against constipation, it is recommended to me on the most vigilant minds. So with us you can get rid of hemorrhoids.

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9 0284 28.1 UAH

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Editorial team

Creation date: 06/04/2022
Update date: 07/09/2023

Pathological state, which is accompanied by increased intervals between bowel movements over two dobies, increases, complications, and systematically insufficient defecation is called constipation.

Illness is characterized by status affiliation, according to WHO data, about 70% of women suffer from illness. The frequency of manifestation of ailments in people grows up to 40 years.

Constipation is characterized by the following symptoms:

• irregular bowel movements;
• hard and dry feces;
• it seems that the intestines are not emptying in full;
• a small amount of feces – less than 35 grams at a norm – 100-150;
• need to strain strongly during defecation;
• abdominal distention.

Doctors see two forms of overcoming constipation, which lie down in the absence of an hour of difficulty in bowel movements:

Before the main signs of constipation, skargs come to:

• decreased appetite;
• vіdrizhku povіtryam;
• appearance of unacceptable prismak in roti;
• opacity and reduced elasticity of the skins.

Causes of indigestion due to fixation

Illness due to unfavorable factors:

How do you classify your property as a security?

Behind the mechanism of small faces, as if a carrying effect may lie down to the next groups:

Representatives of this group are to pick up, and then strengthen the motherland at the ducts of the mucosal-intestinal tract, which will lead to an improvement in the obligation of the intestinal cavity and a decrease in the discharge, and the normalization of the functions of the intestine. The cycles are characterized by a minimum of side effects, but they can also improve the intake of other medications.
• Contact carriers that stimulate intestinal peristalsis. Before them, bring tablets, to the warehouse of which include sodium picosulfate and others.

The action of drugs inducing stimulation of receptors in the mucous membrane of the colon, as a result, increased secretion of electrolytes and water in the distal intestinal tract, accelerated contraction of the walls of the colon, rozm’yakshuєtsya feces and defecation. Pharmacological effect develops in 6-10 years after oral administration of the drug.

Salt passages, for which osmotically increases the secretion of radium and electrolytes in the lumen of the intestinal intestine, which leads to the expansion of the fecal mass and relief of defecation.
The preparations are taken with acute fastening, as well as with severe disorders.

• Osmotic carrying – faces, like avenging lactulose.

Preparations can be seen up to “soft” carrying, like invigorating the microflora, increasing the osmotic pressure on the intestines, illuminating up to the new water. Defecation sets in after three years, if not after 2 days.

The subgroup is supplemented with drugs based on electrolytes – sulfates of sodium, potassium and magnesium, and a macro-spoluk type of macrogol. Many of them belong to the category of prescription drugs and are prescribed older before x-ray obstruction of the intestine or operations.

• Protective care – help to loosen feces, quickly pushing them into the intestines.

To effective medicinal forms for children and grown-ups, as it is necessary for women and mothers, to lay candles, microclysters and rare rectal gels. Faces are injected near the rectum, de-stimulating receptors in the mucous membrane of the intestine and strengthening peristalsis. Medicines help to clear the intestines after 10-20 minutes.

What kind of medicines can be used to take drugs and fix them?

Combination therapy for constipation is aimed not only at improving the patient’s condition, but also at causing problems, including taking medications, such as:

• ;
• regulate the motility of the duct and intestine;
• restore the intestinal microflora.

Patients are advised to:

• improve their quality of life;
• unique stresses;
• zbіshiti ruhovu aktivnіst way bіzichnyh pravd, yakі podpomozhut possilit posіlії peristaltіku kіvkіvіn – їzditi bikіlі, bіgatі, go, swim, do dances аbo yoga;
• dotremuvatsya diet, as a spryyaє normalization of peristalsis and reduction of rozm’yakshennya fecal mass.

Supplement the diet:

• even more, to avenge the rich growth fibers – bananas, dried apricots and prunes;
• boiled carrots and beets;
• spinach;
• kvassole and peas;
• fermented milk products, shards of lactic bacteria improve the work of the organs of etching and the prostate intestine.

In case of some kind of illness, it is not possible to take faces against it?

On the pharmaceutical market of Ukraine there is a wide range of drugs that cause defecation. In some cases, a carrier drug is not prescribed, which can be congested with vaccinia and breastfeeding, it is written in the instructions of the virobnik.

It is important to remember for the ailing that you should not take constipation when:

Cleansing enemas are not possible to cure sickness, in those who suffer from a decrease in immunity in case of SNID or leukemia, shards of the disease are caused by the ingestion of pathogenic bacteria in the intestine.

I’ll fix the skin, I’ll fix it properly, I’ll give you the right to help the doctor after the frontal obstezhennya sick.

References

1. ncbi.nlm.nih.gov;
2. Sovereign register of medicines of Ukraine;
3. nhs.uk.

Popular nutrition

How to relieve calorie in case of constipation?

Even before the day of defecation, symptoms do not come, if you need to go to the doctor, – an increase in temperature and a sharp pain in the abdominal cavity, then empty the intestines to help if there is any carrying through in the form of a suppository iv aborectal microclysters.

To help you get better, and to avoid constipation, doctors recommend:

• Take small portions five times a day.
• add 4-6 drops per day to zhu roslinnі olії, and also increase the infusion of rіdini up to two liters.

What work, how hard is it?

As an alternative to the intake of carry-on remedies, it allows you to quickly loosen the stool, and clean the intestines more thoroughly – clean the enema, as it is used to relieve constipation, as well as in cases of diarrhea before surgery and canopies.

For the preparation of rosemary at home, the patient can vicorate olive, llana, vaseline and other olives. To relieve spasms, loosen feces and speed up bowel movement, heat the oil up to 37 degrees before administering enemas to the rectum.

How long can a person not go to the toilet in a big way?

With normal functioning of the organs of the mucosal-intestinal tract, defecation occurs 1-3 times a day. Ale vіdsutnіst vіdsutnіst vyporozhnen protyazh dіb tezh vvazhаєєєєєєєєєє і to fall in іd іndivіdіdualnyh osobennosti organіzmu. If the intestines are not deformed in humans, they do not stretch out three times, water is lost, fecal masses are strengthened, and constipation develops. It is important for any sick person to understand that it is necessary to turn to the doctor.

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