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Lymph nodes swelling armpits. Lymph Node Surgery for Breast Cancer: Understanding Procedures and Implications

What are the different types of lymph node surgeries for breast cancer. How do doctors determine which lymph nodes to remove. What are the potential complications of lymph node removal. How can patients manage side effects after lymph node surgery.

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The Role of Lymph Nodes in Breast Cancer Spread

Breast cancer’s potential to spread beyond its initial site makes understanding lymph node involvement crucial. When breast cancer metastasizes, it typically first reaches the lymph nodes in the armpit (axilla) near the breast. These lymph nodes are responsible for draining lymphatic fluid from the breast and arm.

Determining the presence and extent of cancer cells in axillary lymph nodes is vital for several reasons:

  • It helps doctors accurately stage the cancer
  • It guides treatment planning
  • It provides valuable prognostic information

Pre-Surgery Lymph Node Assessment

Before breast cancer surgery, doctors employ various techniques to evaluate the lymph nodes:

Ultrasound Scanning

An ultrasound scan of the armpit is typically performed to examine the lymph nodes near the affected breast. This non-invasive imaging technique helps identify any nodes that appear abnormal or suspicious.

Lymph Node Biopsy

If the ultrasound reveals concerning lymph nodes, a biopsy is usually conducted. This involves removing a small sample of tissue from the suspicious node and sending it to a laboratory for analysis. The biopsy results guide the next steps in treatment.

Are biopsies always necessary? Not always. If the ultrasound shows normal-looking lymph nodes, a biopsy may be deferred in favor of a sentinel lymph node biopsy (SLNB) performed during the main breast surgery.

Sentinel Lymph Node Biopsy (SLNB): A Targeted Approach

The sentinel lymph node biopsy is a sophisticated technique used to identify and examine the first lymph node(s) that receive drainage from the breast tumor. This procedure is typically carried out during the primary breast cancer surgery.

The SLNB Procedure

  1. A small amount of radioactive tracer is injected near the tumor a few hours before surgery.
  2. During the operation, the surgeon may also inject a blue dye into the breast.
  3. The combination of radioactive tracer and dye helps pinpoint the sentinel node(s).
  4. The surgeon removes 1-3 sentinel nodes for examination.

Why is the sentinel node so important? The sentinel node acts as a gatekeeper. If it’s free of cancer cells, it’s highly likely that the cancer hasn’t spread to other lymph nodes, potentially sparing the patient from more extensive surgery.

Post-SLNB Scenarios

The results of the sentinel node biopsy determine the next steps:

  • If the sentinel nodes are cancer-free, no further lymph node removal is necessary.
  • If cancer cells are detected, an axillary lymph node dissection (ALND) is typically recommended.

Axillary Lymph Node Dissection (ALND): When More Extensive Surgery is Needed

An axillary lymph node dissection involves removing most or all of the lymph nodes under the arm. This more extensive procedure is performed when:

  • The sentinel node biopsy reveals cancer cells
  • Pre-surgical tests indicate significant lymph node involvement

The ALND Procedure

During an ALND:

  • The patient is under general anesthesia
  • The surgeon makes an incision in the armpit
  • Typically, 10-15 lymph nodes are removed (though this can vary)
  • The removed nodes are sent for pathological examination

How long does it take to get ALND results? Patients usually receive their results at a follow-up appointment about two weeks after surgery.

Intraoperative Assessment: Real-Time Decision Making

Some hospitals offer intraoperative assessment of sentinel lymph nodes. This means that the nodes are analyzed for cancer cells during the initial surgery, allowing for immediate decision-making.

Benefits of intraoperative assessment include:

  • Potentially avoiding a second surgery
  • Streamlining the treatment process
  • Reducing patient anxiety and wait times for results

Is intraoperative assessment available everywhere? No, this option depends on the hospital’s capabilities and protocols. Patients should discuss this possibility with their surgeon before the operation.

Radiotherapy as an Alternative to Surgery

In some cases, radiotherapy may be recommended instead of surgical lymph node removal. This non-invasive approach uses targeted radiation to destroy cancer cells in the lymph nodes.

Factors that may influence the choice of radiotherapy over surgery include:

  • The extent of lymph node involvement
  • The patient’s overall health and ability to tolerate surgery
  • The specific characteristics of the breast cancer
  • Patient preferences and quality of life considerations

Potential Complications of Lymph Node Surgery

While lymph node surgery is an important part of breast cancer treatment, it can lead to certain complications. The risk of these issues is generally higher with more extensive procedures like ALND.

Lymphedema: A Common Concern

Lymphedema is a condition characterized by swelling in the arm or hand on the affected side. It occurs when lymph fluid can’t drain properly due to the removal of lymph nodes.

Key points about lymphedema:

  • It can develop any time after surgery or radiotherapy to the armpit
  • Not all patients will experience lymphedema
  • The risk is lower with sentinel node biopsy compared to full axillary dissection
  • Early detection and management can help control symptoms

Other Potential Complications

Additional issues that may arise after lymph node surgery include:

  • Numbness or altered sensation in the upper arm
  • Limited range of motion in the shoulder
  • Increased risk of infection in the affected arm
  • Seroma formation (fluid accumulation at the surgical site)

How can patients minimize these risks? Following post-operative instructions carefully, engaging in prescribed exercises, and promptly reporting any concerning symptoms to the healthcare team are crucial steps.

Managing Side Effects and Recovery After Lymph Node Surgery

Recovery from lymph node surgery requires patience and proper care. Here are some strategies to manage potential side effects and promote healing:

Lymphedema Prevention and Management

  • Wear compression garments as recommended by your doctor
  • Engage in gentle exercises to promote lymph drainage
  • Avoid injury or infection to the affected arm
  • Consider working with a lymphedema specialist for tailored advice

Pain Management

Post-operative pain is common but can be managed through:

  • Prescribed pain medications
  • Cold or heat therapy (as advised by your healthcare team)
  • Gentle stretching exercises
  • Relaxation techniques

Regaining Mobility

Restoring arm and shoulder function is crucial. Patients may benefit from:

  • Physical therapy
  • Gradual increase in arm exercises
  • Adherence to the post-operative exercise plan provided by the surgical team

When can patients expect to regain full mobility? The timeline varies, but most patients see significant improvement within a few months with proper care and rehabilitation.

Emotional Support

The emotional impact of cancer treatment, including lymph node surgery, shouldn’t be underestimated. Patients may find support through:

  • Counseling or therapy
  • Support groups for breast cancer survivors
  • Open communication with friends and family
  • Mindfulness and stress-reduction techniques

Long-Term Considerations and Follow-Up Care

After lymph node surgery, ongoing monitoring and care are essential. Long-term considerations include:

Regular Check-ups

Patients should adhere to a follow-up schedule determined by their oncology team. These appointments may involve:

  • Physical examinations
  • Imaging studies
  • Blood tests
  • Discussions about any new symptoms or concerns

Lifestyle Adjustments

Some lifestyle modifications may be necessary to protect the affected arm and reduce the risk of complications:

  • Avoiding blood draws or blood pressure measurements on the affected arm
  • Using extra care during activities that could lead to cuts or burns
  • Maintaining a healthy weight to reduce strain on the lymphatic system
  • Staying physically active within the limits advised by the healthcare team

Ongoing Lymphedema Management

For patients who develop lymphedema, long-term management strategies may include:

  • Regular use of compression garments
  • Manual lymphatic drainage techniques
  • Specialized exercises
  • Careful skin care to prevent infections

Is lymphedema reversible? While it can’t always be completely reversed, proper management can significantly improve symptoms and prevent progression.

Monitoring for Recurrence

Patients who have undergone lymph node surgery should be vigilant about potential signs of cancer recurrence. These may include:

  • New lumps or swelling in the breast, chest wall, or armpit
  • Persistent pain in the breast or armpit area
  • Skin changes on the breast or chest wall
  • Unexplained weight loss or fatigue

Any concerning symptoms should be promptly reported to the healthcare team for evaluation.

Advances in Lymph Node Surgery and Future Directions

The field of breast cancer treatment, including lymph node surgery, continues to evolve. Some promising areas of research and development include:

Minimally Invasive Techniques

Researchers are exploring less invasive methods for lymph node assessment and removal, aiming to reduce complications and improve recovery times.

Improved Imaging Technologies

Advanced imaging techniques may allow for more accurate identification of affected lymph nodes, potentially reducing the need for extensive surgery.

Personalized Treatment Approaches

As our understanding of breast cancer biology improves, treatment plans, including decisions about lymph node surgery, may become increasingly tailored to individual patients based on genetic and molecular factors.

Enhanced Rehabilitation Protocols

Ongoing research aims to optimize post-surgical rehabilitation strategies to improve functional outcomes and quality of life for breast cancer survivors.

How might these advances impact patients in the future? They could lead to more precise treatments, faster recoveries, and better long-term outcomes for those undergoing lymph node surgery as part of their breast cancer treatment.

In conclusion, lymph node surgery plays a crucial role in breast cancer treatment, providing valuable information for staging and guiding further treatment decisions. While it can lead to certain complications, advancements in surgical techniques, supportive care, and long-term management strategies continue to improve outcomes for patients. As research progresses, we can expect even more refined and personalized approaches to lymph node assessment and treatment in breast cancer care.

Surgery to remove lymph nodes | Breast cancer

Breast cancer can spread to other parts of the body. If it does spread, it usually first spreads to the lymph nodes in the armpit (axilla) close to the breast. These lymph nodes drain the lymphatic fluid from the breast and arm.

It is important to know if there are cancer cells in the lymph nodes in the armpit and how many. This helps the doctors work out the stage of your cancer and plan the best treatment for you.

Checking the lymph nodes before surgery

Before your surgery you have an ultrasound scan to check the lymph nodes in the armpit close to the breast. This is to see if they contain cancer cells. 

You usually have a biopsy of any lymph nodes that look abnormal. The biopsy is sent to the laboratory to check for cancer cells.

If this shows that the cancer has spread to the nodes in the armpit, you will have surgery to remove all or most of them. You have this at the same time as your breast surgery. This is called an axillary lymph node dissection (ALND) or clearance.

If the lymph nodes look normal during the ultrasound scan, you don’t have a biopsy. But you will have a sentinel lymph node biopsy (SLNB) at the same time as your breast surgery. You have this to check if cancer cells have spread to the nearby lymph nodes.

Checking lymph nodes during surgery (sentinel lymph node biopsy)

The sentinel node is the first node that fluid drains to from the breast into the armpit. This means it’s the first lymph node the breast cancer could spread to.

Your surgeon usually carries out a sentinel lymph node biopsy (SLNB) during the operation to remove your breast cancer. You have about 1 to 3 nodes removed to see if they contain cancer cells.

How you have a sentinel lymph node biopsy

A few hours before the operation, you have an injection of a small amount of mildly radioactive liquid into your breast close to the cancer. You usually have this in the nuclear medicine department in the hospital. The radioactive liquid is called a tracer.

During the operation, your surgeon may also inject a small amount of blue dye into the breast. The dye and the tracer drain away from the breast tissue into nearby lymph nodes.

The surgeon can see which group of lymph nodes the dye reaches first. They also use a radioactive monitor to see which group of lymph nodes the tracer gets to first.

Your surgeon removes between 1 to 3 nodes. They are sent to the laboratory to be looked at by a specialist called a pathologist. 

The dye can stain your breast slightly blue. It gradually fades over a few weeks or months. The dye also turns your urine green for a few days.

What happens after a sentinel node biopsy?

If the lymph nodes do not contain cancer cells, you won’t need to have any more nodes taken out.

If cancer cells are in the sentinel nodes, you have another operation to remove most or all of the lymph nodes under your arm. This is an axillary lymph node dissection or clearance. You generally have it about 2 weeks after you get the results.

Some people have radiotherapy to the armpit to destroy any remaining cancer cells instead of surgery.

Getting the results during surgery

In some hospitals, the surgeon gets the results of the sentinel lymph node biopsy during the operation. This is called an intra operative assessment. They can remove the rest of the nodes (axillary lymph node dissection) if necessary. You then avoid having a second operation.

Your surgeon will explain this to you before your operation, so you know what to expect. 

Removing most or all of the lymph nodes

An operation to remove most or all of the lymph nodes under the arm is called an axillary lymph node dissection or axillary clearance.

You have a general anaesthetic for this operation. You will be asleep the whole time.

The surgeon makes a small cut in your armpit to remove the lymph nodes. Generally, they remove between 10 and 15 lymph nodes. But the number of nodes in the armpit varies from person to person.

The surgeon sends the lymph nodes to the laboratory. A pathologist checks them for cancer cells. You get the results at your follow up appointment, about 2 weeks after surgery.

Some people will have radiotherapy to the lymph nodes instead of surgery.

Problems after removing lymph nodes

There are some possible problems after having surgery to the lymph nodes in your axilla. Not everyone will have these but there is a bigger risk if you have an axillary dissection.

A swollen arm or hand

You are at risk of long term swelling (lymphoedema) in your hand and arm after surgery to remove your lymph nodes in the armpit. This is swelling caused by lymph fluid that can’t drain away. It can happen any time after surgery and radiotherapy to your armpit. 

Not everyone will get this and it is less likely to happen if you only have a few nodes removed. But it is very important to speak to your specialist nurse or surgeon if you think your arm or hand may be swollen. 

Unfortunately, once you have lymphoedema it can’t be cured. But early treatment can help to control it. Your nurse will talk to you about ways of preventing lymphoedema.

Shoulder stiffness

Your shoulder might become stiff and painful after breast surgery to the lymph nodes.
Your nurse or a physiotherapist will show you exercises to do after your operation to help improve movement in the shoulder.

Scar tissue in the armpit (cording)

Some women develop scar tissue in the armpit after lymph node removal. The connective tissues in the armpit get inflamed, which forms one or more tight bands. This usually happens within the first few weeks or months after the operation.

The scar tissue is called cording or banding or axillary web syndrome. It can feel something like a guitar string. It can extend down the arm past the elbow, possibly as far as the wrist or thumb.

Cording is harmless but can be painful and can limit your arm movement. Massaging the area regularly can help. Tell your breast care nurse if you develop cording. They can refer you to a physiotherapist. They can show you how to massage the area and teach you stretching exercises. It usually gets better within a few months. Taking anti inflammatory painkillers may also help. Speak to your nurse or doctor about taking these. 

  • Early Breast Cancer: ESMO Clinical Practice Guidelines 2019
    F Cardoso and others
    Annals of Oncology, 2019. Volume 30, Issue 8, Pages 1194–1220

  • Early and locally advanced breast cancer: diagnosis and treatment
    National Institute for Health and Care Excellence (NICE) June  2018

  • Treatment of primary breast cancer
    Scottish Intercollegiate Guidelines Network, September 2013

  • A systematic review of axillary web syndrome (AWS)
    WM Yeung and others
    Journal of Cancer Survivorship, 2015. Volume 9, Issue 4, Pages 576 – 598

Last reviewed: 

10 Jul 2020

Next review due: 

10 Jul 2023