What are the common uses of magaldrate. How does magaldrate work as an antacid. What are the potential side effects of magaldrate. Who should avoid taking magaldrate. How should magaldrate be taken for maximum effectiveness. What interactions can occur with magaldrate. When should you seek medical attention while taking magaldrate.

Understanding Magaldrate: A Powerful Antacid for Digestive Relief

Magaldrate is a potent antacid medication used to neutralize stomach acid and provide relief from various digestive issues. This oral medication is primarily prescribed to alleviate symptoms associated with heartburn, acid indigestion, and stomach upset. In some cases, healthcare providers may recommend magaldrate for the treatment of more serious conditions such as gastroesophageal reflux disease (GERD) or stomach and duodenal ulcers.

What sets magaldrate apart from other antacids? Its unique composition allows it to effectively neutralize stomach acid while also providing a protective coating to the stomach lining. Some formulations of magaldrate may also include simethicone, an ingredient known for its ability to reduce gas and bloating.

Key Benefits of Magaldrate

• Rapid relief from heartburn and acid indigestion
• Effective neutralization of stomach acid
• Potential protective effects on stomach lining
• May help in the management of GERD and ulcers
• Some formulations aid in reducing gas and bloating

Magaldrate Formulations and Administration Guidelines

Magaldrate is available in various formulations to suit different preferences and needs. These may include chewable tablets, fizzing tablets, and liquid suspensions. The choice of formulation can affect both the onset of action and the overall effectiveness of the medication.

How should magaldrate be taken for maximum effectiveness? Follow these guidelines:

1. Always adhere to the dosage instructions provided by your healthcare provider or the product label.
2. For chewable tablets, thoroughly chew before swallowing to ensure faster relief.
3. When using fizzing tablets, allow them to dissolve completely in water before consuming.
4. If using a liquid formulation, shake well before each use and use a proper measuring device for accurate dosing.
5. Take magaldrate at least 2 hours before or after other medications to avoid potential interactions.

What is the recommended duration for taking magaldrate? While it can be used for short-term relief of occasional symptoms, prolonged use should only occur under the guidance of a healthcare professional. For conditions like stomach ulcers, your doctor may prescribe a specific treatment duration.

Potential Side Effects and Safety Considerations

Like all medications, magaldrate can cause side effects in some individuals. While many people tolerate the medication well, it’s essential to be aware of potential adverse reactions.

Common Side Effects

• Constipation
• Nausea
• Diarrhea
• Loss of appetite
• Headache
• Stomach cramps

What are the more serious side effects that require immediate medical attention? While rare, severe reactions can occur. Seek emergency care if you experience:

• Signs of an allergic reaction (hives, difficulty breathing, swelling of face, lips, tongue, or throat)
• Irregular heartbeat
• Severe stomach pain
• Extreme weakness or fatigue
• Significant mood changes or confusion
• Severe muscle pain

Precautions and Contraindications for Magaldrate Use

While magaldrate is generally considered safe for most adults, certain individuals should exercise caution or avoid its use altogether. Who should be particularly cautious when considering magaldrate?

• Individuals with a history of kidney disease
• Those with liver problems
• People on low-sodium or low-magnesium diets
• Individuals with phenylketonuria (PKU), as some formulations contain phenylalanine
• Pregnant or breastfeeding women (consult with a healthcare provider first)
• Children under 12 years old (use only under medical supervision)

What conditions might contraindicate the use of magaldrate? Never take this medication if you have symptoms suggestive of appendicitis or bowel inflammation, such as severe abdominal pain, vomiting, or bloody stools. In such cases, seek immediate medical attention.

Magaldrate Interactions with Other Medications and Substances

Magaldrate can interact with various medications and substances, potentially altering their effectiveness or increasing the risk of side effects. What are some key interactions to be aware of?

• Antibiotics: Magaldrate may reduce the absorption of certain antibiotics, particularly tetracyclines and fluoroquinolones.
• Iron supplements: The antacid properties of magaldrate can interfere with iron absorption.
• Thyroid medications: Magaldrate may affect the absorption of levothyroxine and similar drugs.
• Blood thinners: Some antacids can interact with warfarin and other anticoagulants.
• Heart medications: Certain antihypertensive and antiarrhythmic drugs may interact with magaldrate.

How can you minimize the risk of drug interactions? Always inform your healthcare provider about all medications, supplements, and herbal products you’re taking. Additionally, maintain a gap of at least 2 hours between taking magaldrate and other medications to reduce the likelihood of interactions.

Long-term Use of Magaldrate: Benefits and Risks

While magaldrate can provide effective relief for acute digestive issues, its long-term use requires careful consideration. What are the potential benefits and risks associated with prolonged magaldrate use?

Potential Benefits

• Ongoing management of chronic acid reflux or GERD
• Protective effects on the stomach lining in ulcer-prone individuals
• Improved quality of life for those with persistent digestive discomfort

Potential Risks

• Electrolyte imbalances, particularly in those with kidney problems
• Potential masking of underlying digestive disorders
• Risk of developing tolerance or dependence on antacids
• Interference with the absorption of essential nutrients over time

How can you safely use magaldrate for extended periods? Always follow your healthcare provider’s recommendations. Regular check-ups and monitoring may be necessary to ensure the continued appropriateness and safety of long-term magaldrate use.

Magaldrate vs. Other Antacids: A Comparative Analysis

With numerous antacid options available, it’s natural to wonder how magaldrate compares to other common choices. What are the key differences between magaldrate and other antacids?

Magaldrate vs. Calcium Carbonate

• Magaldrate may cause less calcium-related side effects
• Calcium carbonate provides additional calcium, which can be beneficial for some individuals
• Magaldrate may be gentler on the digestive system for long-term use

Magaldrate vs. Aluminum Hydroxide

• Both have similar acid-neutralizing capabilities
• Magaldrate may have a lower risk of causing constipation
• Aluminum hydroxide might be preferred for those needing to limit magnesium intake

Magaldrate vs. Proton Pump Inhibitors (PPIs)

• Magaldrate provides more immediate relief but shorter duration of action
• PPIs are more effective for long-term acid suppression but take longer to start working
• Magaldrate has fewer systemic effects compared to PPIs

How do you choose the right antacid? The choice depends on individual factors such as the severity and frequency of symptoms, underlying health conditions, and potential drug interactions. Consult with a healthcare provider to determine the most appropriate option for your specific situation.

Lifestyle Modifications to Complement Magaldrate Treatment

While magaldrate can effectively manage acid-related digestive issues, combining medication with lifestyle changes can lead to better outcomes. What lifestyle modifications can enhance the effectiveness of magaldrate treatment?

1. Dietary adjustments:
   • Avoid trigger foods such as spicy, acidic, or fatty items
   • Eat smaller, more frequent meals to reduce stomach acid production
   • Limit alcohol and caffeine consumption
2. Positional changes:
   • Elevate the head of your bed to reduce nighttime reflux
   • Avoid lying down immediately after meals
3. Stress management:
   • Practice relaxation techniques like deep breathing or meditation
   • Engage in regular exercise to reduce stress and improve digestion
4. Weight management:
   • Maintain a healthy weight to reduce pressure on the stomach and lower esophageal sphincter
5. Smoking cessation:
   • Quit smoking to improve overall digestive health and reduce acid reflux symptoms

How can these lifestyle changes complement magaldrate treatment? By addressing the underlying causes of acid-related issues, these modifications can help reduce the frequency and severity of symptoms, potentially decreasing reliance on medication over time.

Future Developments in Antacid Therapy: Beyond Magaldrate

As medical research continues to advance, new approaches to managing acid-related digestive disorders are emerging. What future developments might we see in antacid therapy?

• Targeted drug delivery systems:
  • Nanoparticle-based antacids for more precise and prolonged acid neutralization
  • pH-responsive formulations that release active ingredients only when needed
• Combination therapies:
  • Antacids combined with probiotics for comprehensive digestive support
  • Dual-action formulations targeting both acid neutralization and mucosal protection
• Personalized medicine approaches:
  • Genetic testing to determine optimal antacid formulations for individuals
  • AI-driven dosing regimens based on real-time symptom monitoring
• Novel compounds:
  • Development of new antacid molecules with improved efficacy and fewer side effects
  • Exploration of natural compounds with acid-neutralizing properties

How might these advancements impact the use of magaldrate and other current antacids? While magaldrate remains an effective option for many, future developments could offer more tailored and efficient solutions for managing acid-related digestive issues. As research progresses, we may see a shift towards more personalized and technologically advanced antacid therapies.

In conclusion, magaldrate stands as a reliable and effective antacid option for many individuals suffering from acid-related digestive issues. Its ability to neutralize stomach acid, coupled with potential protective effects on the stomach lining, makes it a valuable tool in managing conditions ranging from occasional heartburn to more chronic issues like GERD. However, as with any medication, it’s crucial to use magaldrate under proper medical guidance, being mindful of potential side effects and interactions. By combining magaldrate treatment with appropriate lifestyle modifications and staying informed about emerging therapies, individuals can optimize their approach to managing digestive health and improving overall quality of life.

Magaldrate Antacids, Oral – Tufts Medical Center Community Care

What are other names for this medicine?

Type of medicine: antacid

Generic and brand names: magaldrate and simethicone, oral; magaldrate, oral

What is this medicine used for?

This medicine is an antacid that neutralizes stomach acid. It is taken by mouth to relieve heartburn, sour stomach, acid indigestion, and stomach upset. It may also be used to treat gastroesophageal reflux disease (GERD) or stomach and duodenal ulcers.

Some antacids contain simethicone, an ingredient that helps get rid of stomach gas.

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

• An allergic reaction to any medicine
• Edema (swelling of the legs and feet)
• Heart disease
• Intestinal or stomach problems such as colitis, diverticulitis, or rectal bleeding
• Kidney or liver disease
• Phenylketonuria (PKU). Some chewable tablets contain phenylalanine

Tell your healthcare provider if you are on a low sodium or low magnesium diet. Some antacids contain high amounts of sodium or magnesium.

Females of childbearing age: Talk with your healthcare provider if you are pregnant, plan to become pregnant, or are breast-feeding.

How do I take it?

Check the label on the medicine for directions about your specific dose. Take this medicine exactly as directed by your healthcare provider, or according to the manufacturer’s directions. Read all information carefully. For stomach or duodenal ulcers, take the medicine for as long as your healthcare provider tells you. Do not miss doses.

Check with your healthcare provider before using this medicine in children. Some brands should not be used in children at all and some should not be used in children under a specific age.

If you are using chewable tablets, chew them well before swallowing for faster relief.

If you are using fizzing tablets, let them dissolve in water and let most of the bubbling stop before you drink the mixture.

If are using a liquid, shake well before taking. Use a special dose measuring spoon or cup to measure out the correct dose.

Take antacids at least 2 hours before or after taking other medicines to avoid interference.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: decreased appetite, trouble urinating, nausea, vomiting, diarrhea, constipation, weakness, confusion, dizziness.

What should I watch out for?

Your healthcare provider may want to see you regularly for checkups if you are taking this medicine for ulcers or another medical condition.

Never take antacids if you have any symptoms of appendicitis or bowel inflammation (severe abdominal pain, vomiting, loose bowel movements, bloody stools). If you have these symptoms, contact your healthcare provider right away.

Do not take this medicine as an antacid for more than 2 weeks unless your healthcare provider tells you to. Tell your healthcare provider if your symptoms do not improve or if they get worse.

Do not give this medicine to children younger than 12 years old without a healthcare provider’s approval.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine. It may change certain lab test results.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Irregular heartbeat, severe stomach pain, severe nausea and vomiting, extreme weakness or tiredness, mood changes, confusion, muscle pain.

Other side effects: Constipation, nausea, diarrhea, loss of appetite, headache, white or pale bowel movements, stomach cramps.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects.

Antacids may interact with many prescription drugs. If you are taking any prescription medicine, do not take antacids without checking with your healthcare provider or pharmacist.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.

This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.

Medication Advisor 2015.1 published by RelayHealth.
Last modified: 2014-02-14
Last reviewed: 2014-01-14

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

Copyright ©1986-2015 McKesson Corporation and/or one of its subsidiaries. All rights reserved.

Magaldrate – Uses, Side Effects, Substitutes, Composition And More

Prescription vs OTC: Prescription by Doctor not required

Magaldrate is primarily used to provide symptomatic relief of hyperacidity associated with peptic ulcer, gastritis, peptic esophagitis and hiatal hernia. Magaldrate is also used to treat a sour stomach, acid indigestion, heartburn and gas. It is an antacid that neutralizes the stomach acid and slowly increases the pH level of the stomach.

Taking anticoagulants and citrate salts may increase the side effects of Magaldrate. Let your doctor know if you are on a low magnesium diet, have appendicitis, kidney and bowel problems, and rectal bleeding. If you have an allergy to Magaldrate or any related medication and food, let your doctor know.

It is in the form of a suspension liquid that can be taken with or without food. Never take a double dose of Magaldrate, it is better that you skip it till the next time you can take it. Remember to ask the doctor any queries that you may have about the medicine and the course of the treatment.

There are very few possible side effects of Magaldrate that include intestinal pain, constipation and diarrhea. More serious side effects that need medical attention are loss of appetite, tarry stools, slow reflexes, vomiting and rashes.

Chew tablets thoroughly before swallowing with water; notify physician if relief is not obtained or if signs of bleeding from GI tract occur.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

The primary use of this medication is as follows:

• Peptic Ulcer

• Gastritis

• Esophagitis

Health issues vary person to person

Take help from the best doctors

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect kidney function?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Below is the list of medicines, which contains Magaldrate as ingredient

View More

This medicine is an antacid drug. It is primarily used to treat esophagitis, duodenal and gastric ulcers. The aluminium magnesium hydroxide present in this medicine neutralizes gastric acid and increases gastric ph which in turn inactivates pepsin.

What are the interactions of Magaldrate ?

Whenever you take more than one medicine, or mix it with certain foods or beverages, you”re at risk of a drug interaction.

References

• Magaldrate-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/magaldrate

• Magaldrate-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 11 June 2022].Available from:

  https://go.drugbank.com/drugs/DB08938

• MAGALDRATE suspension,solution-DailyMed [Internet].

  dailymed.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=MAGALDRATE

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details

Written By

Drx Hina Firdous

PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma – Certificate in Nutrition and Child Care

Pharmacology

Reviewed By

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MBBS, Master in Healthcare Administration, Diploma in Occupational Health

General Physician

Table of Content

About Magaldrate

What are the uses of Magaldrate

What are the contraindications of Magaldrate ?

What are the side effects of Magaldrate ?

Key highlights of Magaldrate

What are the dosage instructions?

Medicines containing Magaldrate

How does this medication work?

What are the interactions of Magaldrate ?

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main drugs and their use

Contents

• 1 Drug treatment of high stomach acid: effective ways!
  • 1.1 Increased acidity of the stomach: causes and symptoms
  • 1. 2 What symptoms accompany increased acidity of the stomach?
  • 1.3 How is hyperacidity diagnosed?
  • 1.4 What groups of drugs are used for hyperacidity of the stomach?
  • 1.5 Antacids for the treatment of hyperacidity of the stomach
  • 1.6 Action of proton pump inhibitors on high stomach acid
  • 1.7 Anticholinergics for the treatment of high stomach acid
  • 1.8 Histamine receptor blockers: mechanism of action
    • 1.8.1 Role of histamine in high stomach acid

    9 0005 1.8.2 How do histamine blockers work? receptors

  • 1.9 Cyprofloxacin-containing drugs for hyperacidity of the stomach
  • 1.10 Antiulcer drugs for the treatment of hyperacidity of the stomach
  • 1.11 Question-answer:
    • • 1.11.0.1 Which drugs are most effective for hyperacidity of the stomach?
      • 1.11.0.2 Are there side effects when using drugs to treat stomach acid?
      • 1.11.0.3 What is the best drug to use to treat peptic ulcer?
      • 1. 11.0.4 What are the symptoms of increased stomach acid?
      • 1.11.0.5 What are the contraindications for the use of proton pump inhibitors?
      • 1.11.0.6 How long should medications be taken for acid stomach?
  • 1.12 How to use medicines for hyperacidity of the stomach?
  • 1.13 Related videos:

Medical treatment of stomach acid – what drugs help to cope with excess stomach acid, and how to use them correctly?

Hyperacidity of the stomach is a common disease that affects the quality of life of many people. Symptoms are discomfort, belching, hot feeling, headache, nausea, and bloating. Medication can help relieve these symptoms, reduce acidity, and prevent recurrences.

The main drugs used to treat stomach acidity include proton pump inhibitors (PPIs), antacids, antisecretory drugs, and prokinetics. PPIs are the main treatment for this disease, they slow down the production of acid in the stomach. Antacids neutralize the acid that is already present in the stomach. Antisecretory drugs reduce the amount of acid produced by the stomach, and prokinetics improve gastric motility.

The choice of remedy depends on the cause of the hyperacidity and the symptoms that the patient is experiencing. In addition, it is necessary to take into account existing side effects and possible interactions with other drugs that the patient is taking. However, the right combination of medications can lead to a quick and effective improvement in health.

Hyperacidity of the stomach: causes and symptoms

Hyperacidity of the stomach is a condition in which the secretion of gastric juice becomes more intense than usual, which leads to irritation of the mucous membrane of the stomach and esophagus. This condition is often accompanied by unpleasant symptoms such as heartburn, nausea, vomiting, stomach and chest pain, belching, loss of appetite, and upset stools. Increased stomach acid can be caused by a variety of reasons, including dietary errors, stress, gastritis, stomach ulcers, and other diseases.

One of the main factors affecting the level of stomach acidity is food . Raw vegetables, fruits, yogurt and other dairy products, and lean meats are foods that help reduce acidity and relax the sphincter that separates the stomach and esophagus. The other side of the coin: fatty, spicy, smoked, sweet, sour and salty foods increase the acidity of the stomach, as well as coffee, alcohol and other irritants.

Symptoms of high stomach acid can occur in people of any age and gender , but most often it affects older people and those who lead an unhealthy lifestyle, are constantly under stress and are in constant motion. They often complain of paroxysmal pain or burning sensation in the epigastric region, nausea, vomiting, belching, stool disorders, dizziness, weakness, and even loss of consciousness.

What symptoms accompany increased stomach acidity?

Stomach hyperacidity is a condition where the acidity level can be higher than normal. One of the main symptoms is a burning sensation in the chest area, which can spread to the throat and make breathing difficult.

Other symptoms of stomach acid include nausea, vomiting, heartburn, and stomach pain. The patient may also experience a feeling of excess food in the stomach, constant hunger, gas and constipation. More severe symptoms, such as bloody stools or vomiting blood, require immediate medical attention.

Stomach acidity can be caused by a variety of factors, including stress, eating irregularities, and disturbed sleep patterns. To avoid stomach acidity and the symptoms associated with it, you need to lead a healthy lifestyle, eat right and improve the quality of sleep.

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How is hyperacidity of the stomach diagnosed?

Stomach acidity may be uncomfortable and harmful to the body. Therefore, it is important to determine the causes of this phenomenon in a timely manner and prescribe the necessary treatment. The following methods are used for diagnostics:

• Fibrogastroduodenoscopy. Allows you to visually assess the condition of the mucous membrane of the stomach and duodenum, to identify the presence of inflammatory or tumor processes.
• Acid-peptic test. Allows you to measure the amount of acid in the stomach, determine its pH and identify hypersecretion.
• Urease test. Allows you to detect the presence of the bacterium Helicobacter pylori, which can cause increased acidity of the stomach and peptic ulcer.

Based on the results of the diagnosis, the doctor prescribes the necessary treatment, including drugs to reduce stomach acid, antibiotics to kill Helicobacter pylori bacteria and other medicines.

What groups of medicines are used for hyperacidity of the stomach?

Several groups of drugs are used to treat high stomach acid. One of the main groups are proton inhibitors – drugs such as omeprazole, pantoprazole, esomeprazole. They reduce the amount of hydrochloric acid secreted by the stomach by blocking proton pumps in the cells of the gastric mucosa.

Another group of medicines is antacids. They reduce acidity in the stomach, but do not affect its production. Antacids, such as aluminum hydroxide, magnesium hydroxide, magaldrate, sodium bicarbonate, sodium polynocynate, eliminate the symptoms of heartburn, relieve feelings of heaviness and pain in the stomach.

Antisecretory agents, such as famotidine, ranitidine, can also be classified as drugs that are used for hyperacidity of the stomach. They also stop the production of excess gastric juice by blocking the h3-histamine receptors in the cells of the stomach and reducing the secretion of acidic contents in the stomach.

1. Proton inhibitors: omeprazole, pantoprazole, esomeprazole
2. Antacids: aluminum hydroxide, magnesium hydroxide, magalrate, sodium bicarbonate, sodium polynocynate
3. Antisecretory agents: famotidine, ranitidine

Antacids to treat high stomach acid

Antacids are medicines used to reduce acidity in the stomach. They neutralize store acid, reduce the acidity of hydrochloric acid and protect the gastric mucosa from damage.

There are several types of antacids that are used to treat stomach acid. Some of them include:

• Aluminum antacids: contains aluminum hydroxide, which reduces stomach acid;
• Magnesium antacids: contains magnesium hydroxide, which rapidly reduces stomach acid;
• Combination antacids: contains both magnesium and aluminum and combines their properties;
• Titanium antacids: contains titanium, which also neutralizes hydrochloric acid.

Before using antacids, it is important to consult your doctor to determine the correct dosage and timing of administration. They can interact with other drugs, so you need to be careful and vigilant.

Proton pump inhibitors for high stomach acid

Proton pump inhibitors are a class of drugs designed specifically for the treatment of gastroesophageal reflux and other conditions associated with high stomach acid. They work by blocking a special pump that is responsible for producing stomach acid. On a physiological level, blocking the pump causes stomach acid to decrease by 90% or more. This allows patients to avoid the pain, discomfort, and acute symptoms associated with stomach acid.

How do proton pump inhibitors work? Their action is based on the fact that they block the enzyme that is responsible for the secretion of gastric acid in the stomach. This is due to a special mechanism of interaction of inhibitors with cellular receptors that receive signals to produce acid in the stomach. Proton pump inhibitors prevent stomach acid from escaping, so patients can avoid the pain and other symptoms associated with high stomach acid.

Proton pump inhibitors are one of the most effective drugs for treating stomach acid. They act fast enough, and the result of their application is felt after some time after taking. However, in order to achieve the maximum effect, proton pump inhibitors must be taken for several days and weeks. In addition, before using proton pump inhibitors, it is important to consult a doctor who will prescribe the dosage and duration of treatment, depending on the individual characteristics of the patient.

Anticholinergics to treat stomach acid

Anticholinergics are used to reduce stomach acid production. The main action of anticholinergic drugs is the blocking of acetylcholine receptors, which leads to a decrease in the production of gastric acid and a decrease in the activity of gastric secretion.

Anticholinergic drugs include a group of anticholinergic myotropic agents such as atropine, hyoscine, metamizole, platyfillin and drotaverine. These drugs block muscarinic cholinergic nerve receptors and can lead to decreased stomach acid production.

The use of anticholinergic drugs is usually prescribed as a symptomatic therapy for gastric and duodenal ulcers, regurgitation, gastroesophageal reflux.

However, before using anticholinergic drugs, it is necessary to consult a doctor and study the instructions for use, as they have a wide range of side effects, such as eye pressure disturbances, dry mucous membranes, impaired thermoregulation, and others.

Histamine receptor blockers: mechanism of action

The role of histamine in gastric acidity

Histamine is one of the key factors in the regulation of gastric acidity. It is synthesized in the gastrin secretory cells of the stomach and released in response to various stimuli such as food, stimulation of the parasympathetic nervous system, and others. Histamine acts on histamine receptors in the cells of the stomach, leading to an increase in acid secretion.

How histamine receptor blockers work

Histamine receptor blockers are the main class of drugs for the treatment of hyperacidity of the stomach. They prevent the binding of histamine to histamine receptors, which leads to a decrease in acid secretion. Most histamine receptor blockers act on h3 receptors, and there are also drugs that act on h4 receptors.

Histamine receptor blockers with varying efficacy and duration reduce stomach acid. They are widely used to treat peptic ulcers, esophagitis, acid reflux, and other conditions associated with high stomach acid. They can also be used to prevent the recurrence of ulcers and to reduce the risk of bleeding from a stomach ulcer.

Cyprofloxacin-containing medicines for stomach acidity

Cyprofloxacin-containing medicines are classified as antibiotics, but can also be used in the treatment of stomach acidity. These drugs have the ability to reduce the healing time of ulcerative lesions of the stomach and duodenum.

Ciprolet is one of the most common ciprofloxacin-containing drugs. It belongs to the group of fluoroquinolone antibiotics and is highly effective in the treatment of stomach ulcers. “Tsiprolet” is recommended to be taken at least 3 times a day after meals for 7-14 days.

• Cyprofloxacin-containing medicines should only be taken with a doctor’s prescription as they may cause side effects;
• Do not take ciprofloxacin with preparations containing magnesium, zinc, aluminium, calcium or iron;
• Cyprofloxacin may increase sensitivity to sunlight, so prolonged sun exposure should be avoided and UV protection should be used.

Antiulcer drugs for the treatment of hyperacidity of the stomach

Stomach acidity is a common disorder that can lead to gastritis, ulcers, and other gastrointestinal problems. Doctors often prescribe anti-ulcer drugs to treat this condition.

Proton sodium pumps (PNP) inhibitors:

• Omeprazole
• Esomeprazole
• Pantoprazole stomach. They are especially effective for treating peptic ulcers, gastritis and reflux.

  Antacids:

  • Malgel
  • Reni
  • Phosphalugel

  These drugs quickly reduce the level of acid in the stomach and have an anti-inflammatory effect. They relieve symptoms of gastritis and ulcers

  Gastrocepin:

  This drug blocks histamine receptors in the stomach, which reduces acid secretion. It is effective for treating gastritis, ulcers and acid reaction in the stomach.

  Follow your doctor’s instructions carefully and do not exceed the recommended dose. If you experience any side effects, contact your doctor immediately.

  Question-answer:

  Which drugs are most effective for hyperacidity of the stomach?

  Proton pump inhibitors such as omeprazole, lansoprazole, esomeprazole, etc. are the most effective drugs for stomach acidity. esophagus.

  Are there any side effects when using drugs to treat high stomach acid?

  Yes, the use of proton pump inhibitors can lead to some side effects such as headache, diarrhea, nausea, constipation, increased sensitivity to light, increased risk of Clostridium difficile infection, and others. However, most patients tolerate these side effects easily and without complications.

  What drug is best used to treat peptic ulcer?

  Proton pump inhibitors, such as omeprazole, lansoprazole, esomeprazole, etc., are most effective in the treatment of peptic ulcers. They block the secretion of stomach acid, which leads to healing of the ulcer and reduces the risk of its recurrence.

  What are the symptoms of increased stomach acid?

  Symptoms of stomach acidity may include bitterness in the mouth, heartburn, belching, upper abdominal pain, nausea, vomiting, loss of appetite, bulky eructations, and others. However, these symptoms can be characteristic of various diseases of the stomach and esophagus, so only a doctor can make an accurate diagnosis.

  What are the contraindications for the use of proton pump inhibitors?

  Contraindications for the use of proton pump inhibitors may include an allergic reaction to the drug components, the presence of hypercalcemia, liver failure, pregnancy and lactation. Also, these drugs can interact with other medicines, which can lead to unwanted effects.

  How long should medications be taken for hyperacidity of the stomach?

  The duration of use of proton pump inhibitors and other drugs with increased stomach acid depends on the severity of the disease, the effectiveness of the drug and a number of other factors. The doctor should prescribe the dose and duration of treatment depending on the individual characteristics of the patient and the severity of the disease.

  How to use medicines for hyperacidity of the stomach?

  Treating stomach acid is a lengthy process that requires daily medication. To get the maximum effect from the drugs, you need to use them correctly.

  First of all, it is necessary to strictly observe the dosage and mode of taking the drugs. Most medicines should be taken half an hour before a meal to ensure maximum effectiveness and not interfere with digestion. An exception may be a medicine that needs to be taken with or after a meal.

  When using several preparations, their compatibility must be taken into account. Some medicines can interact with each other and cause unwanted side effects. This is especially important to consider when using different groups of drugs at the same time.

  Be sure to consult your doctor about possible side effects and contraindications to the use of medicines. Some drugs may be harmful to health in certain conditions or if the person is taking certain other drugs.

  In general, successful treatment of hyperacidity of the stomach depends on adherence to the correct regimen of medications and their compatibility with each other. Talk to your doctor for personalized advice on medication use and treatment plan.

  Video on the topic:

  Instructions for use of the drug Riopan suspension for oral administration 800 mg, 10 ml sachet No. 20

  Composition of the medicinal product

  active substance: magaldrate;

  Riopan 800 mg sachet contains 800 mg anhydrous magalrate;

  Riopan 1600 mg sachet contains 1600 mg anhydrous magalrate;

  excipients: acacia (gum arabic), hypromellose, maltol, sodium cyclamate, simethicone emulsion 30%, silver sulfate (E 174), chlorhexidine bigluconate solution 20%, flavored cream, flavored caramel, sodium hypochlorite, purified water.

  Dosage form

  Oral suspension.

  White, creamy and caramel-scented suspension.

  Manufacturer’s name and location

  Takeda GmbH, Germany.

  Robert Bosch-Strasse 8, 78224 Singen, Germany

  Pharmacological group

  Antacids. Combined preparations and complex compounds of aluminum, calcium and magnesium.

  ATC code А02А D02.

  Riopan is an antacid agent with acid-neutralizing properties. The action of magaldrate is based on the immediate regulation of gastric juice. Neutralizes hydrochloric acid in the stomach, reduces the activity of pepsin. It has an adsorbing and enveloping effect. Adsorbs bile acids and lysolecithin, protecting the gastric mucosa. Magaldrata does not affect gastric motility.

  Magaldrata is not absorbed from the digestive tract. In the process of neutralization, a small amount of magnesium and aluminum ions are released, which are converted in the intestines into sparingly soluble phosphates and excreted in the feces. Some of the cations are absorbed, so there may be a slight increase in the level of aluminum in the blood serum. Long-term use of aluminum-containing antacids may reduce phosphate absorption.

  Indications

  • Heartburn and acid-related diseases of the stomach.
  • Symptomatic treatment of gastric and duodenal ulcers.

  Contraindications

  Hypersensitivity to drug components.

  Special precautions

  With prolonged use of the drug, it is necessary to control the level of aluminum in the blood plasma (the concentration of aluminum should not exceed 40 ng / ml).

  Use with caution in patients with impaired renal function (creatinine clearance

  In rare cases, after the use of the drug in high doses for several years, a decrease in the absorption of calcium and phosphates was observed, followed by osteomalacia.

  In case of persistent disorders, with periodic improvement in symptoms or frequent relapses, it is necessary to consult a doctor and make sure that there are no serious underlying diseases.

  If laboratory tests for H. Pylori are positive in patients with gastric and duodenal ulcers, standard antibiotic therapy should be considered.

  Riopan does not contain sugar and can be used to treat patients with diabetes.

  Use during pregnancy and lactation

  The drug during pregnancy can be used only after a thorough assessment of the possible benefits to the pregnant woman and the potential risk to the fetus, since there are not enough clinical data on the use of the drug in pregnant women. To prevent aluminum intoxication, it is recommended to take the drug for a short time and in the minimum possible use.

  Ryopan should be used with caution during lactation. Aluminum compounds pass into breast milk in very small amounts due to poor absorption and do not pose a potential threat to infants.

  Ability to influence the reaction rate when driving motor transport or operating other mechanisms

  No effect.

  Children

  There are no clinical data on the use of the drug in children.

  Dosage and administration

  The recommended dose is 1-2 sachets several times a day.

  The maximum daily dose is 8 sachets of 800 mg or 4 sachets of 1600 mg

  (6.4 g of magalrate).

  The Riopan sachet must be shaken before use.

  Riopan is used for symptomatic treatment.

  If symptoms persist after 2 weeks of treatment, follow-up clinical evaluation is required.

  Elderly patients does not require dose adjustment.

  Overdose

  No cases of overdose with Riopan have been reported.

  Side effects

  Side effects according to the frequency of occurrence are classified into the following categories: very often ( > 10%), often ( > 1% – <10%), infrequently ( > 0.1% – < 1%), rare ( > 0.01% – <0.1%), very rare (<1/10000, including isolated cases).

  From the digestive tract.

  Loose stools very often.

  Very rare diarrhea.

  Research . In patients with renal insufficiency or with prolonged use in high doses of the drug, an increase in the level of aluminum and magnesium in the blood serum is possible, which can lead to the accumulation of aluminum, mainly in the nervous and bone tissues, and to a deficiency of phosphates.

  Interaction with other drugs and other forms of interaction.

  When taking Riopan and other drugs, an interval of at least 2:00 should be observed, since antacids may reduce the absorption of other drugs. Perhaps a significant decrease in the absorption of antibiotics, including tetracycline, quinolone antibiotics (ofloxacin, norfloxacin); a slight decrease in the absorption of digoxin, isoniazid, iron preparations, chlorpromazine; potential enhancement of the action of coumarin anticoagulants.

  Antacids containing aluminum should not be used with acidic drinks (fruit juices, wines, etc.) or effervescent tablets containing citric or tartaric acid, as absorption of aluminum from the intestine is enhanced.