What are the primary uses of magaldrate. How does magaldrate work as an antacid. What are the common side effects of magaldrate. Who should avoid taking magaldrate. How should magaldrate be taken for optimal results. What precautions should be considered when using magaldrate. Can magaldrate interact with other medications.

Understanding Magaldrate: An Overview of This Antacid Medication

Magaldrate is an antacid medication used to neutralize stomach acid and provide relief from various gastrointestinal discomforts. As a member of the antacid family, it plays a crucial role in managing conditions related to excess stomach acid. But what exactly is magaldrate, and how does it work?

Magaldrate is a compound of aluminum hydroxide and magnesium hydroxide. Its primary function is to neutralize stomach acid, which helps alleviate symptoms associated with various digestive issues. When taken orally, magaldrate reacts with the hydrochloric acid in the stomach, effectively reducing its acidity and providing relief from associated symptoms.

Key Features of Magaldrate:

• Fast-acting antacid
• Neutralizes stomach acid
• Available in various forms (tablets, liquid)
• May contain additional ingredients like simethicone for gas relief

Primary Uses and Benefits of Magaldrate

Magaldrate is prescribed or recommended for a variety of gastrointestinal conditions. Its versatility makes it a popular choice for both over-the-counter and prescription use. But what specific conditions can magaldrate help with?

The primary uses of magaldrate include:

1. Relief from heartburn
2. Treatment of acid indigestion
3. Alleviation of sour stomach
4. Management of gastroesophageal reflux disease (GERD)
5. Treatment of stomach and duodenal ulcers

Is magaldrate effective for all these conditions? While magaldrate can provide relief for many individuals suffering from these issues, its effectiveness may vary depending on the severity of the condition and individual factors. For chronic or severe cases, it’s essential to consult with a healthcare provider to determine the most appropriate treatment plan.

Potential Side Effects and Risks of Magaldrate

Like all medications, magaldrate can cause side effects in some individuals. While many people tolerate the medication well, it’s crucial to be aware of potential adverse reactions. What are the most common side effects associated with magaldrate use?

Common Side Effects:

• Constipation
• Nausea
• Diarrhea
• Loss of appetite
• Headache
• White or pale bowel movements
• Stomach cramps

Are there any serious side effects to be concerned about? While rare, some individuals may experience more severe reactions to magaldrate. These can include:

Serious Side Effects:

• Irregular heartbeat
• Severe stomach pain
• Extreme weakness or tiredness
• Mood changes
• Confusion
• Muscle pain

In case of any severe side effects or allergic reactions (such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat), it’s crucial to seek immediate medical attention.

Proper Usage and Dosage Guidelines for Magaldrate

To maximize the benefits of magaldrate while minimizing potential risks, it’s essential to use the medication correctly. How should magaldrate be taken for optimal results?

General Usage Guidelines:

• Follow the dosage instructions provided by your healthcare provider or on the product label
• Take magaldrate exactly as directed
• For chewable tablets, chew thoroughly before swallowing
• For liquid forms, shake well before use and use a proper measuring device
• Take at least 2 hours before or after other medications to avoid interactions

Can magaldrate be used long-term? While magaldrate is generally safe for short-term use, it’s not recommended to use it for more than two weeks without consulting a healthcare provider. Prolonged use may mask underlying conditions or lead to electrolyte imbalances.

Precautions and Contraindications for Magaldrate Use

Before starting magaldrate, it’s crucial to consider various factors that may affect its safety and efficacy. Who should exercise caution or avoid using magaldrate altogether?

Individuals Who Should Use Caution:

• Those with kidney disease
• Individuals with liver problems
• People on low-sodium or low-magnesium diets
• Pregnant or breastfeeding women
• Those with a history of edema (swelling)
• Individuals with heart disease

Are there any specific conditions that contraindicate magaldrate use? Magaldrate should be avoided in cases of:

• Known allergy to any of its ingredients
• Appendicitis or suspected appendicitis
• Severe abdominal pain of unknown origin
• Phenylketonuria (PKU), if using formulations containing phenylalanine

It’s always best to consult with a healthcare provider before starting any new medication, including over-the-counter antacids like magaldrate.

Magaldrate Interactions with Other Medications and Substances

Magaldrate can interact with various medications and substances, potentially altering their effectiveness or increasing the risk of side effects. What are some important interactions to be aware of?

Common Drug Interactions:

• Antibiotics (e.g., tetracyclines, quinolones)
• Iron supplements
• Thyroid medications
• Certain heart medications
• Some anti-seizure drugs

How can these interactions be managed? To minimize the risk of interactions, it’s recommended to take magaldrate at least 2 hours before or after other medications. Always inform your healthcare provider about all medications, supplements, and herbal products you’re taking before starting magaldrate.

Comparing Magaldrate to Other Antacids: Pros and Cons

With numerous antacid options available, it’s natural to wonder how magaldrate compares to other choices. What are the advantages and disadvantages of magaldrate compared to other antacids?

Advantages of Magaldrate:

• Effective acid neutralization
• Generally well-tolerated
• Available in various forms for ease of use
• Can provide quick relief from heartburn and indigestion

Potential Disadvantages:

• May cause constipation in some individuals
• Not suitable for long-term use without medical supervision
• Can interact with various medications
• May not be appropriate for those with certain health conditions

How does magaldrate compare to popular alternatives like calcium carbonate or proton pump inhibitors? While magaldrate is effective for many individuals, the choice of antacid depends on various factors, including the specific condition being treated, individual health status, and potential side effects. Consulting with a healthcare provider can help determine the most suitable option for each individual case.

Long-term Considerations and Alternatives to Magaldrate

While magaldrate can be effective for short-term relief of acid-related symptoms, it’s important to consider long-term management strategies for chronic conditions. What should individuals with persistent symptoms consider beyond magaldrate use?

Long-term Management Strategies:

• Dietary modifications (e.g., avoiding trigger foods)
• Lifestyle changes (e.g., weight management, stress reduction)
• Exploring alternative medications (e.g., H2 blockers, proton pump inhibitors)
• Investigating underlying causes of persistent symptoms

Are there natural alternatives to magaldrate? Some individuals may find relief from mild symptoms through natural remedies such as:

• Ginger tea
• Chamomile tea
• Aloe vera juice
• Baking soda in water (used cautiously and in moderation)

It’s important to note that while these natural remedies may provide relief for some, they are not substitutes for medical treatment in cases of severe or chronic acid-related conditions. Always consult with a healthcare provider before relying on natural remedies, especially for persistent or severe symptoms.

Understanding the Mechanism of Action: How Magaldrate Works

To fully appreciate the benefits and limitations of magaldrate, it’s crucial to understand its mechanism of action. How exactly does magaldrate neutralize stomach acid and provide relief from associated symptoms?

Magaldrate works through a chemical reaction within the stomach. When ingested, it dissociates into its component parts: aluminum hydroxide and magnesium hydroxide. These compounds then react with the hydrochloric acid in the stomach, effectively neutralizing it. This reaction produces water and neutral salts, which do not contribute to stomach acidity.

Key Points in Magaldrate’s Mechanism:

• Rapid acid neutralization upon ingestion
• Formation of water and neutral salts
• Temporary increase in stomach pH
• Relief from acid-related symptoms like heartburn and indigestion

Does the acid-neutralizing effect of magaldrate last long? The effect of magaldrate is relatively short-lived, typically providing relief for a few hours. This is why it’s often recommended for occasional use or as needed, rather than as a long-term solution for chronic acid-related conditions.

Special Considerations for Magaldrate Use in Specific Populations

While magaldrate is generally safe for many adults, special considerations are necessary for certain populations. How should magaldrate use be approached in children, elderly individuals, and pregnant or breastfeeding women?

Magaldrate Use in Children:

Caution is advised when using magaldrate in children. Some key points to consider include:

• Many formulations are not recommended for children under 12 years old
• Dosage should be carefully adjusted based on age and weight
• Pediatric use should always be under the guidance of a healthcare provider

Considerations for Elderly Patients:

Elderly individuals may be more susceptible to certain side effects and interactions. Important factors include:

• Increased risk of electrolyte imbalances
• Potential for drug interactions due to multiple medications
• Possible need for dosage adjustments

Use During Pregnancy and Breastfeeding:

Pregnant and breastfeeding women should exercise caution with magaldrate use:

• Limited data on safety during pregnancy
• Potential for magnesium accumulation in breast milk
• Consultation with a healthcare provider is essential

Is magaldrate safe for individuals with chronic health conditions? Those with chronic conditions, especially kidney or liver disease, should use magaldrate only under close medical supervision due to the potential for electrolyte imbalances and other complications.

Recognizing and Managing Magaldrate Overdose

While magaldrate is generally safe when used as directed, overdose is possible and can lead to serious complications. How can one recognize the signs of magaldrate overdose, and what steps should be taken in such cases?

Symptoms of Magaldrate Overdose:

• Decreased appetite
• Difficulty urinating
• Severe nausea and vomiting
• Diarrhea or constipation
• Extreme weakness
• Confusion or dizziness

What should be done in case of suspected overdose? If an overdose is suspected, it’s crucial to seek immediate medical attention. Contact emergency services or the local poison control center (800-222-1222 in the United States) for guidance. Do not induce vomiting unless explicitly instructed to do so by a medical professional.

Prevention and Safety Measures:

• Always follow recommended dosages
• Keep magaldrate out of reach of children
• Do not combine with other antacids without medical advice
• Be aware of the magaldrate content in combination products

By understanding the potential for overdose and taking appropriate precautions, individuals can safely use magaldrate while minimizing risks.

The Future of Acid Reflux Treatment: Beyond Magaldrate

As medical research advances, new approaches to treating acid reflux and related conditions are emerging. What does the future hold for acid reflux treatment, and how might it impact the use of traditional antacids like magaldrate?

Emerging Treatment Approaches:

• Targeted medications with fewer side effects
• Personalized treatment based on genetic factors
• Advanced surgical techniques for severe cases
• Integration of lifestyle modifications and medical treatments

Will magaldrate become obsolete in the face of new treatments? While newer treatments may offer advantages for certain patients, magaldrate and other traditional antacids are likely to remain valuable options for many individuals, particularly for occasional or mild symptoms. The future of acid reflux treatment will likely involve a combination of traditional and innovative approaches, tailored to individual patient needs.

Ongoing Research Areas:

• Understanding the gut microbiome’s role in acid reflux
• Developing novel drug delivery systems for more effective treatment
• Exploring the potential of probiotics in managing acid-related conditions
• Investigating the long-term effects of various treatment approaches

As research progresses, individuals with acid reflux and related conditions may benefit from an expanding array of treatment options, potentially leading to more effective and personalized care.

Magaldrate Antacids, Oral – Tufts Medical Center Community Care

What are other names for this medicine?

Type of medicine: antacid

Generic and brand names: magaldrate and simethicone, oral; magaldrate, oral

What is this medicine used for?

This medicine is an antacid that neutralizes stomach acid. It is taken by mouth to relieve heartburn, sour stomach, acid indigestion, and stomach upset. It may also be used to treat gastroesophageal reflux disease (GERD) or stomach and duodenal ulcers.

Some antacids contain simethicone, an ingredient that helps get rid of stomach gas.

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

• An allergic reaction to any medicine
• Edema (swelling of the legs and feet)
• Heart disease
• Intestinal or stomach problems such as colitis, diverticulitis, or rectal bleeding
• Kidney or liver disease
• Phenylketonuria (PKU). Some chewable tablets contain phenylalanine

Tell your healthcare provider if you are on a low sodium or low magnesium diet. Some antacids contain high amounts of sodium or magnesium.

Females of childbearing age: Talk with your healthcare provider if you are pregnant, plan to become pregnant, or are breast-feeding.

How do I take it?

Check the label on the medicine for directions about your specific dose. Take this medicine exactly as directed by your healthcare provider, or according to the manufacturer’s directions. Read all information carefully. For stomach or duodenal ulcers, take the medicine for as long as your healthcare provider tells you. Do not miss doses.

Check with your healthcare provider before using this medicine in children. Some brands should not be used in children at all and some should not be used in children under a specific age.

If you are using chewable tablets, chew them well before swallowing for faster relief.

If you are using fizzing tablets, let them dissolve in water and let most of the bubbling stop before you drink the mixture.

If are using a liquid, shake well before taking. Use a special dose measuring spoon or cup to measure out the correct dose.

Take antacids at least 2 hours before or after taking other medicines to avoid interference.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: decreased appetite, trouble urinating, nausea, vomiting, diarrhea, constipation, weakness, confusion, dizziness.

What should I watch out for?

Your healthcare provider may want to see you regularly for checkups if you are taking this medicine for ulcers or another medical condition.

Never take antacids if you have any symptoms of appendicitis or bowel inflammation (severe abdominal pain, vomiting, loose bowel movements, bloody stools). If you have these symptoms, contact your healthcare provider right away.

Do not take this medicine as an antacid for more than 2 weeks unless your healthcare provider tells you to. Tell your healthcare provider if your symptoms do not improve or if they get worse.

Do not give this medicine to children younger than 12 years old without a healthcare provider’s approval.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine. It may change certain lab test results.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Irregular heartbeat, severe stomach pain, severe nausea and vomiting, extreme weakness or tiredness, mood changes, confusion, muscle pain.

Other side effects: Constipation, nausea, diarrhea, loss of appetite, headache, white or pale bowel movements, stomach cramps.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects.

Antacids may interact with many prescription drugs. If you are taking any prescription medicine, do not take antacids without checking with your healthcare provider or pharmacist.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.

This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.

Medication Advisor 2015.1 published by RelayHealth.
Last modified: 2014-02-14
Last reviewed: 2014-01-14

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

Copyright ©1986-2015 McKesson Corporation and/or one of its subsidiaries. All rights reserved.

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main drugs and their use

Contents

• 1 Drug treatment of high stomach acid: effective ways!
  • 1.1 Increased acidity of the stomach: causes and symptoms
  • 1.2 What symptoms accompany increased acidity of the stomach?
  • 1.3 How is hyperacidity diagnosed?
  • 1.4 What groups of drugs are used for hyperacidity of the stomach?
  • 1.5 Antacids for the treatment of hyperacidity of the stomach
  • 1.6 Action of proton pump inhibitors on high stomach acid
  • 1.7 Anticholinergics for the treatment of high stomach acid
  • 1. 8 Histamine receptor blockers: mechanism of action
    • 1.8.1 Role of histamine in high stomach acid

    9 0005 1.8.2 How do histamine blockers work? receptors

  • 1.9 Cyprofloxacin-containing drugs for hyperacidity of the stomach
  • 1.10 Antiulcer drugs for the treatment of hyperacidity of the stomach
  • 1.11 Question-answer:
    • • 1.11.0.1 Which drugs are most effective for hyperacidity of the stomach?
      • 1.11.0.2 Are there side effects when using drugs to treat stomach acid?
      • 1.11.0.3 What is the best drug to use to treat peptic ulcer?
      • 1.11.0.4 What are the symptoms of increased stomach acid?
      • 1.11.0.5 What are the contraindications for the use of proton pump inhibitors?
      • 1.11.0.6 How long should medications be taken for acid stomach?
  • 1.12 How to use medicines for hyperacidity of the stomach?
  • 1.13 Related videos:

Medical treatment of stomach acid – what drugs help to cope with excess stomach acid, and how to use them correctly?

Hyperacidity of the stomach is a common disease that affects the quality of life of many people. Symptoms are discomfort, belching, hot feeling, headache, nausea, and bloating. Medication can help relieve these symptoms, reduce acidity, and prevent recurrences.

The main drugs used to treat stomach acidity include proton pump inhibitors (PPIs), antacids, antisecretory drugs, and prokinetics. PPIs are the main treatment for this disease, they slow down the production of acid in the stomach. Antacids neutralize the acid that is already present in the stomach. Antisecretory drugs reduce the amount of acid produced by the stomach, and prokinetics improve gastric motility.

The choice of remedy depends on the cause of the hyperacidity and the symptoms that the patient is experiencing. In addition, it is necessary to take into account existing side effects and possible interactions with other drugs that the patient is taking. However, the right combination of medications can lead to a quick and effective improvement in health.

Hyperacidity of the stomach: causes and symptoms

Hyperacidity of the stomach is a condition in which the secretion of gastric juice becomes more intense than usual, which leads to irritation of the mucous membrane of the stomach and esophagus. This condition is often accompanied by unpleasant symptoms such as heartburn, nausea, vomiting, stomach and chest pain, belching, loss of appetite, and upset stools. Increased stomach acid can be caused by a variety of reasons, including dietary errors, stress, gastritis, stomach ulcers, and other diseases.

One of the main factors affecting the level of stomach acidity is food . Raw vegetables, fruits, yogurt and other dairy products, and lean meats are foods that help reduce acidity and relax the sphincter that separates the stomach and esophagus. The other side of the coin: fatty, spicy, smoked, sweet, sour and salty foods increase the acidity of the stomach, as well as coffee, alcohol and other irritants.

Symptoms of high stomach acid can occur in people of any age and gender , but most often it affects older people and those who lead an unhealthy lifestyle, are constantly under stress and are in constant motion. They often complain of paroxysmal pain or burning sensation in the epigastric region, nausea, vomiting, belching, stool disorders, dizziness, weakness, and even loss of consciousness.

What symptoms accompany increased stomach acidity?

Stomach hyperacidity is a condition where the acidity level can be higher than normal. One of the main symptoms is a burning sensation in the chest area, which can spread to the throat and make breathing difficult.

Other symptoms of stomach acid include nausea, vomiting, heartburn, and stomach pain. The patient may also experience a feeling of excess food in the stomach, constant hunger, gas and constipation. More severe symptoms, such as bloody stools or vomiting blood, require immediate medical attention.

Stomach acidity can be caused by a variety of factors, including stress, eating irregularities, and disturbed sleep patterns. To avoid stomach acidity and the symptoms associated with it, you need to lead a healthy lifestyle, eat right and improve the quality of sleep.

State polyclinics and hospitals

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Private clinics and med. centers

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How is hyperacidity of the stomach diagnosed?

Stomach acidity may be uncomfortable and harmful to the body. Therefore, it is important to determine the causes of this phenomenon in a timely manner and prescribe the necessary treatment. The following methods are used for diagnostics:

• Fibrogastroduodenoscopy. Allows you to visually assess the condition of the mucous membrane of the stomach and duodenum, to identify the presence of inflammatory or tumor processes.
• Acid-peptic test. Allows you to measure the amount of acid in the stomach, determine its pH and identify hypersecretion.
• Urease test. Allows you to detect the presence of the bacterium Helicobacter pylori, which can cause increased acidity of the stomach and peptic ulcer.

Based on the results of the diagnosis, the doctor prescribes the necessary treatment, including drugs to reduce stomach acid, antibiotics to kill Helicobacter pylori bacteria and other medicines.

What groups of medicines are used for hyperacidity of the stomach?

Several groups of drugs are used to treat high stomach acid. One of the main groups are proton inhibitors – drugs such as omeprazole, pantoprazole, esomeprazole. They reduce the amount of hydrochloric acid secreted by the stomach by blocking proton pumps in the cells of the gastric mucosa.

Another group of medicines is antacids. They reduce acidity in the stomach, but do not affect its production. Antacids, such as aluminum hydroxide, magnesium hydroxide, magaldrate, sodium bicarbonate, sodium polynocynate, eliminate the symptoms of heartburn, relieve feelings of heaviness and pain in the stomach.

Antisecretory agents, such as famotidine, ranitidine, can also be classified as drugs that are used for hyperacidity of the stomach. They also stop the production of excess gastric juice by blocking the h3-histamine receptors in the cells of the stomach and reducing the secretion of acidic contents in the stomach.

1. Proton inhibitors: omeprazole, pantoprazole, esomeprazole
2. Antacids: aluminum hydroxide, magnesium hydroxide, magalrate, sodium bicarbonate, sodium polynocynate
3. Antisecretory agents: famotidine, ranitidine

Antacids to treat high stomach acid

Antacids are medicines used to reduce acidity in the stomach. They neutralize store acid, reduce the acidity of hydrochloric acid and protect the gastric mucosa from damage.

There are several types of antacids that are used to treat stomach acid. Some of them include:

• Aluminum antacids: contains aluminum hydroxide, which reduces stomach acid;
• Magnesium antacids: contains magnesium hydroxide, which rapidly reduces stomach acid;
• Combination antacids: contains both magnesium and aluminum and combines their properties;
• Titanium antacids: contains titanium, which also neutralizes hydrochloric acid.

Before using antacids, it is important to consult your doctor to determine the correct dosage and timing of administration. They can interact with other drugs, so you need to be careful and vigilant.

Proton pump inhibitors for high stomach acid

Proton pump inhibitors are a class of drugs designed specifically for the treatment of gastroesophageal reflux and other conditions associated with high stomach acid. They work by blocking a special pump that is responsible for producing stomach acid. On a physiological level, blocking the pump causes stomach acid to decrease by 90% or more. This allows patients to avoid the pain, discomfort, and acute symptoms associated with stomach acid.

How do proton pump inhibitors work? Their action is based on the fact that they block the enzyme that is responsible for the secretion of gastric acid in the stomach. This is due to a special mechanism of interaction of inhibitors with cellular receptors that receive signals to produce acid in the stomach. Proton pump inhibitors prevent stomach acid from escaping, so patients can avoid the pain and other symptoms associated with high stomach acid.

Proton pump inhibitors are one of the most effective drugs for treating stomach acid. They act fast enough, and the result of their application is felt after some time after taking. However, in order to achieve the maximum effect, proton pump inhibitors must be taken for several days and weeks. In addition, before using proton pump inhibitors, it is important to consult a doctor who will prescribe the dosage and duration of treatment, depending on the individual characteristics of the patient.

Anticholinergics to treat stomach acid

Anticholinergics are used to reduce stomach acid production. The main action of anticholinergic drugs is the blocking of acetylcholine receptors, which leads to a decrease in the production of gastric acid and a decrease in the activity of gastric secretion.

Anticholinergic drugs include a group of anticholinergic myotropic agents such as atropine, hyoscine, metamizole, platyfillin and drotaverine. These drugs block muscarinic cholinergic nerve receptors and can lead to decreased stomach acid production.

The use of anticholinergic drugs is usually prescribed as a symptomatic therapy for gastric and duodenal ulcers, regurgitation, gastroesophageal reflux.

However, before using anticholinergic drugs, it is necessary to consult a doctor and study the instructions for use, as they have a wide range of side effects, such as eye pressure disturbances, dry mucous membranes, impaired thermoregulation, and others.

Histamine receptor blockers: mechanism of action

The role of histamine in gastric acidity

Histamine is one of the key factors in the regulation of gastric acidity. It is synthesized in the gastrin secretory cells of the stomach and released in response to various stimuli such as food, stimulation of the parasympathetic nervous system, and others. Histamine acts on histamine receptors in the cells of the stomach, leading to an increase in acid secretion.

How histamine receptor blockers work

Histamine receptor blockers are the main class of drugs for the treatment of hyperacidity of the stomach. They prevent the binding of histamine to histamine receptors, which leads to a decrease in acid secretion. Most histamine receptor blockers act on h3 receptors, and there are also drugs that act on h4 receptors.

Histamine receptor blockers with varying efficacy and duration reduce stomach acid. They are widely used to treat peptic ulcers, esophagitis, acid reflux, and other conditions associated with high stomach acid. They can also be used to prevent the recurrence of ulcers and to reduce the risk of bleeding from a stomach ulcer.

Cyprofloxacin-containing medicines for stomach acidity

Cyprofloxacin-containing medicines are classified as antibiotics, but can also be used in the treatment of stomach acidity. These drugs have the ability to reduce the healing time of ulcerative lesions of the stomach and duodenum.

Ciprolet is one of the most common ciprofloxacin-containing drugs. It belongs to the group of fluoroquinolone antibiotics and is highly effective in the treatment of stomach ulcers. “Tsiprolet” is recommended to be taken at least 3 times a day after meals for 7-14 days.

• Cyprofloxacin-containing medicines should only be taken with a doctor’s prescription as they may cause side effects;
• Do not take ciprofloxacin with preparations containing magnesium, zinc, aluminium, calcium or iron;
• Cyprofloxacin may increase sensitivity to sunlight, so prolonged sun exposure should be avoided and UV protection should be used.

Antiulcer drugs for the treatment of hyperacidity of the stomach

Stomach acidity is a common disorder that can lead to gastritis, ulcers, and other gastrointestinal problems. Doctors often prescribe anti-ulcer drugs to treat this condition.

Proton sodium pumps (PNP) inhibitors:

• Omeprazole
• Esomeprazole
• Pantoprazole stomach. They are especially effective for treating peptic ulcers, gastritis and reflux.

  Antacids:

  • Malgel
  • Reni
  • Phosphalugel

  These drugs quickly reduce the level of acid in the stomach and have an anti-inflammatory effect. They relieve symptoms of gastritis and ulcers

  Gastrocepin:

  This drug blocks histamine receptors in the stomach, which reduces acid secretion. It is effective for treating gastritis, ulcers and acid reaction in the stomach.

  Follow your doctor’s instructions carefully and do not exceed the recommended dose. If you experience any side effects, contact your doctor immediately.

  Question-answer:

  Which drugs are most effective for hyperacidity of the stomach?

  Proton pump inhibitors such as omeprazole, lansoprazole, esomeprazole, etc. are the most effective drugs for stomach acidity. esophagus.

  Are there any side effects when using drugs to treat high stomach acid?

  Yes, the use of proton pump inhibitors can lead to some side effects such as headache, diarrhea, nausea, constipation, increased sensitivity to light, increased risk of Clostridium difficile infection, and others. However, most patients tolerate these side effects easily and without complications.

  What drug is best used to treat peptic ulcer?

  Proton pump inhibitors, such as omeprazole, lansoprazole, esomeprazole, etc., are most effective in the treatment of peptic ulcers. They block the secretion of stomach acid, which leads to healing of the ulcer and reduces the risk of its recurrence.

  What are the symptoms of increased stomach acid?

  Symptoms of stomach acidity may include bitterness in the mouth, heartburn, belching, upper abdominal pain, nausea, vomiting, loss of appetite, bulky eructations, and others. However, these symptoms can be characteristic of various diseases of the stomach and esophagus, so only a doctor can make an accurate diagnosis.

  What are the contraindications for the use of proton pump inhibitors?

  Contraindications for the use of proton pump inhibitors may include an allergic reaction to the drug components, the presence of hypercalcemia, liver failure, pregnancy and lactation. Also, these drugs can interact with other medicines, which can lead to unwanted effects.

  How long should medications be taken for hyperacidity of the stomach?

  The duration of use of proton pump inhibitors and other drugs with increased stomach acid depends on the severity of the disease, the effectiveness of the drug and a number of other factors. The doctor should prescribe the dose and duration of treatment depending on the individual characteristics of the patient and the severity of the disease.

  How to use medicines for hyperacidity of the stomach?

  Treating stomach acid is a lengthy process that requires daily medication. To get the maximum effect from the drugs, you need to use them correctly.

  First of all, it is necessary to strictly observe the dosage and mode of taking the drugs. Most medicines should be taken half an hour before a meal to ensure maximum effectiveness and not interfere with digestion. An exception may be a medicine that needs to be taken with or after a meal.

  When using several preparations, their compatibility must be taken into account. Some medicines can interact with each other and cause unwanted side effects. This is especially important to consider when using different groups of drugs at the same time.

  Be sure to consult your doctor about possible side effects and contraindications to the use of medicines. Some drugs may be harmful to health in certain conditions or if the person is taking certain other drugs.

  In general, successful treatment of hyperacidity of the stomach depends on adherence to the correct regimen of medications and their compatibility with each other. Talk to your doctor for personalized advice on medication use and treatment plan.

  Video on the topic:

  Instructions for use of the drug Riopan suspension for oral administration 800 mg, 10 ml sachet No. 20

  Composition of the medicinal product

  active substance: magaldrate;

  Riopan 800 mg sachet contains 800 mg anhydrous magalrate;

  Riopan 1600 mg sachet contains 1600 mg anhydrous magalrate;

  excipients: acacia (gum arabic), hypromellose, maltol, sodium cyclamate, simethicone emulsion 30%, silver sulfate (E 174), chlorhexidine bigluconate solution 20%, flavored cream, flavored caramel, sodium hypochlorite, purified water.

  Dosage form

  Oral suspension.

  White, creamy and caramel-scented suspension.

  Manufacturer’s name and location

  Takeda GmbH, Germany.

  Robert Bosch-Strasse 8, 78224 Singen, Germany

  Pharmacological group

  Antacids. Combined preparations and complex compounds of aluminum, calcium and magnesium.

  ATC code А02А D02.

  Riopan is an antacid agent with acid-neutralizing properties. The action of magaldrate is based on the immediate regulation of gastric juice. Neutralizes hydrochloric acid in the stomach, reduces the activity of pepsin. It has an adsorbing and enveloping effect. Adsorbs bile acids and lysolecithin, protecting the gastric mucosa. Magaldrata does not affect gastric motility.

  Magaldrata is not absorbed from the digestive tract. In the process of neutralization, a small amount of magnesium and aluminum ions are released, which are converted in the intestines into sparingly soluble phosphates and excreted in the feces. Some of the cations are absorbed, so there may be a slight increase in the level of aluminum in the blood serum. Long-term use of aluminum-containing antacids may reduce phosphate absorption.

  Indications

  • Heartburn and acid-related diseases of the stomach.
  • Symptomatic treatment of gastric and duodenal ulcers.

  Contraindications

  Hypersensitivity to drug components.

  Special precautions

  With prolonged use of the drug, it is necessary to control the level of aluminum in the blood plasma (the concentration of aluminum should not exceed 40 ng / ml).

  Use with caution in patients with impaired renal function (creatinine clearance

  In rare cases, after the use of the drug in high doses for several years, a decrease in the absorption of calcium and phosphates was observed, followed by osteomalacia.

  In case of persistent disorders, with periodic improvement in symptoms or frequent relapses, it is necessary to consult a doctor and make sure that there are no serious underlying diseases.

  If laboratory tests for H. Pylori are positive in patients with gastric and duodenal ulcers, standard antibiotic therapy should be considered.

  Riopan does not contain sugar and can be used to treat patients with diabetes.

  Use during pregnancy and lactation

  The drug during pregnancy can be used only after a thorough assessment of the possible benefits to the pregnant woman and the potential risk to the fetus, since there are not enough clinical data on the use of the drug in pregnant women. To prevent aluminum intoxication, it is recommended to take the drug for a short time and in the minimum possible use.

  Ryopan should be used with caution during lactation. Aluminum compounds pass into breast milk in very small amounts due to poor absorption and do not pose a potential threat to infants.

  Ability to influence the reaction rate when driving motor transport or operating other mechanisms

  No effect.

  Children

  There are no clinical data on the use of the drug in children.

  Dosage and administration

  The recommended dose is 1-2 sachets several times a day.

  The maximum daily dose is 8 sachets of 800 mg or 4 sachets of 1600 mg

  (6.4 g of magalrate).

  The Riopan sachet must be shaken before use.

  Riopan is used for symptomatic treatment.

  If symptoms persist after 2 weeks of treatment, follow-up clinical evaluation is required.

  Elderly patients does not require dose adjustment.

  Overdose

  No cases of overdose with Riopan have been reported.

  Side effects

  Side effects according to the frequency of occurrence are classified into the following categories: very often ( > 10%), often ( > 1% – <10%), infrequently ( > 0.1% – < 1%), rare ( > 0.01% – <0.1%), very rare (<1/10000, including isolated cases).

  From the digestive tract.

  Loose stools very often.

  Very rare diarrhea.

  Research . In patients with renal insufficiency or with prolonged use in high doses of the drug, an increase in the level of aluminum and magnesium in the blood serum is possible, which can lead to the accumulation of aluminum, mainly in the nervous and bone tissues, and to a deficiency of phosphates.

  Interaction with other drugs and other forms of interaction.

  When taking Riopan and other drugs, an interval of at least 2:00 should be observed, since antacids may reduce the absorption of other drugs. Perhaps a significant decrease in the absorption of antibiotics, including tetracycline, quinolone antibiotics (ofloxacin, norfloxacin); a slight decrease in the absorption of digoxin, isoniazid, iron preparations, chlorpromazine; potential enhancement of the action of coumarin anticoagulants.

  Antacids containing aluminum should not be used with acidic drinks (fruit juices, wines, etc.) or effervescent tablets containing citric or tartaric acid, as absorption of aluminum from the intestine is enhanced.