How does manganese contribute to overall health. What are the recommended daily intakes of manganese for different age groups. Which foods are rich sources of manganese. Can manganese supplementation have any side effects.

What is Manganese and Its Role in Human Health

Manganese is a vital mineral that plays a crucial role in maintaining optimal health. This trace element is essential for various bodily functions, including energy production, cell protection, and bone formation. But what exactly does manganese do in our bodies?

Manganese serves as a cofactor for numerous enzymes, facilitating important biochemical processes. It contributes to:

• Energy production in cells
• Protection of cells from oxidative damage
• Formation and maintenance of strong bones
• Proper functioning of the reproductive system
• Blood clotting
• Supporting a healthy immune system

Is manganese deficiency common? Manganese deficiency is extremely rare in the United States, as most people obtain sufficient amounts through their diet. However, in the rare cases where deficiency occurs, it can lead to various health issues.

Recommended Daily Intake of Manganese

The required amount of manganese varies depending on age and sex. Here are the average daily recommended amounts in milligrams (mg):

• Infants 0-6 months: 0.003 mg
• Infants 7-12 months: 0.6 mg
• Children 1-3 years: 1.2 mg
• Children 4-8 years: 1.5 mg
• Boys 9-13 years: 1.9 mg
• Girls 9-13 years: 1.6 mg
• Teen boys 14-18 years: 2.2 mg
• Teen girls 14-18 years: 1.6 mg
• Adult men: 2.3 mg
• Adult women: 1.8 mg
• Pregnant teens and women: 2.0 mg
• Breastfeeding teens and women: 2.6 mg

Are these recommendations sufficient for optimal health? For most individuals, adhering to these guidelines ensures adequate manganese intake. However, specific health conditions or dietary restrictions may necessitate adjustments in consultation with a healthcare provider.

Dietary Sources of Manganese

Manganese is present in a wide variety of foods, making it relatively easy to obtain through a balanced diet. Some of the best sources include:

• Whole grains (brown rice, oatmeal, whole-wheat bread)
• Shellfish (clams, oysters, mussels)
• Nuts (hazelnuts, pecans)
• Legumes (soybeans, lentils)
• Leafy green vegetables (spinach, kale)
• Certain fruits (pineapple, blueberries)
• Tea
• Various spices, particularly black pepper

Can a varied diet provide sufficient manganese? For most people, consuming a diverse range of these foods ensures adequate manganese intake without the need for supplementation.

Manganese Supplements: Types and Considerations

While most individuals obtain sufficient manganese from their diet, supplements are available for those who may require additional intake. Manganese supplements come in various forms, including:

• Manganese sulfate
• Manganese aspartate
• Multivitamin/multimineral complexes containing manganese

Is one form of manganese supplement superior to others? Current scientific evidence does not indicate that any particular form of manganese in supplements is more effective or better absorbed than others. When considering supplementation, it’s crucial to consult with a healthcare provider to determine if it’s necessary and, if so, which form and dosage are most appropriate.

Potential Health Benefits of Manganese

Ongoing research is exploring the various ways manganese may impact health. Some areas of particular interest include:

Bone Health

Manganese, in combination with other minerals and vitamins, is essential for healthy bone formation. However, more research is needed to fully understand its role in maintaining or improving bone health. Does manganese alone significantly impact bone density? While manganese is crucial for bone health, it works synergistically with other nutrients, and its isolated effect on bone density is still being studied.

Diabetes Management

Manganese plays a role in carbohydrate metabolism, helping to break down starches and sugars. However, its direct effect on diabetes risk or management is not yet fully understood. Can manganese supplementation help manage blood sugar levels? While manganese is involved in glucose metabolism, there’s insufficient evidence to support manganese supplementation as a diabetes management strategy. More research is needed to clarify its potential role.

Manganese Toxicity and Upper Limits

While manganese is essential for health, excessive intake can lead to toxicity. Manganese toxicity is rare from dietary sources alone but can occur from:

• Consuming water with very high manganese levels
• Inhaling large amounts of manganese dust (e.g., in mining or welding work)

Symptoms of manganese toxicity may include:

• Tremors and muscle spasms
• Hearing problems
• Mania or depression
• Insomnia
• Loss of appetite
• Headaches
• Irritability and mood changes
• Weakness

To prevent potential toxicity, upper limits for manganese intake have been established:

• Children 1-3 years: 2 mg
• Children 4-8 years: 3 mg
• Children 9-13 years: 6 mg
• Teens 14-18 years: 9 mg
• Adults: 11 mg
• Pregnant and breastfeeding teens: 9 mg
• Pregnant and breastfeeding adults: 11 mg

These upper limits include intake from all sources – food, beverages, and supplements. Can exceeding these limits cause immediate harm? While occasional slight exceedances are unlikely to cause immediate issues, consistent intake above the upper limits may lead to adverse effects over time. It’s crucial to stay within recommended ranges unless advised otherwise by a healthcare provider.

Manganese Interactions with Medications and Other Supplements

Currently, there are no known interactions between manganese and medications. However, it’s always important to inform your healthcare providers about all dietary supplements and medications you’re taking. This helps ensure:

• No potential interactions are overlooked
• Supplements don’t interfere with medication efficacy
• Medications don’t affect manganese absorption or utilization

Should individuals on certain medications be cautious about manganese intake? While no specific interactions are known, those on long-term medications or with chronic health conditions should consult their healthcare provider about appropriate manganese intake.

Incorporating Manganese into a Balanced Diet

Obtaining manganese through a varied, balanced diet is the most effective and safest approach for most individuals. Here are some tips to ensure adequate manganese intake:

1. Include whole grains in your diet regularly
2. Incorporate a variety of nuts and legumes into your meals
3. Consume leafy green vegetables frequently
4. Enjoy fruits like pineapple and blueberries as healthy snacks
5. Consider drinking tea, which is a good source of manganese
6. Use spices liberally in cooking, especially black pepper

Is it necessary to track manganese intake meticulously? For most healthy individuals, consciously including a variety of manganese-rich foods in their diet is sufficient without the need for precise tracking. However, those with specific health concerns or dietary restrictions may benefit from more careful monitoring in consultation with a nutritionist or healthcare provider.

By understanding the role of manganese in our bodies and incorporating manganese-rich foods into our diets, we can support overall health and well-being. Remember, while manganese is essential, balance is key. Always consult with healthcare professionals before making significant changes to your diet or starting any new supplement regimen.

As research continues to uncover more about the potential benefits and optimal intake of manganese, staying informed and maintaining a balanced approach to nutrition remains the best strategy for most individuals. By doing so, we can harness the benefits of this essential mineral while minimizing any potential risks associated with excessive intake.

Manganese – Consumer

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What is manganese and what does it do?

Manganese is a mineral that your body needs to stay healthy. Your body uses manganese to make energy and protect your cells from damage. Your body also needs manganese for strong bones, reproduction, blood clotting, and a healthy immune system.

How much manganese do I need?

The amount of manganese you need depends on your age and sex. Average daily recommended amounts are listed below in milligrams (mg).

Life Stage	Recommended Amount
Birth to 6 months	0.003 mg
Infants 7–12 months	0.6 mg
Children 1–3 years	1. 2 mg
Children 4–8 years	1.5 mg
Boys 9–13 years	1.9 mg
Girls 9–13 years	1.6 mg
Teen boys 14–18 years	2.2 mg
Teen girls 14–18 years	1.6 mg
Adult men	2.3 mg
Adult women	1.8 mg
Pregnant teens and women	2.0 mg
Breastfeeding teens and women	2.6 mg

What foods provide manganese?

Many foods contain manganese. You can get recommended amounts of manganese by eating a variety of foods, including the following:

• Whole grains, such as brown rice, oatmeal, and whole-wheat bread
• Clams, oysters, and mussels
• Nuts, such as hazelnuts and pecans
• Legumes, such as soybeans and lentils
• Leafy vegetables, such as spinach and kale
• Some fruits, such as pineapple and blueberries
• Tea
• Many spices, such as black pepper

What kinds of manganese dietary supplements are available?

Manganese is available in many multivitamin/multimineral and other dietary supplements. Supplements contain many forms of manganese, such as manganese sulfate and manganese aspartate. Scientists don’t know whether any form of manganese in supplements is better than any other form.

Am I getting enough manganese?

Most people in the United States get enough manganese from the foods they eat.

What happens if I don’t get enough manganese?

Manganese deficiency is very rare in the United States. A deficiency might cause the following symptoms:

• Weak bones and poor growth in children
• Skin rashes and loss of hair color in men
• Mood changes and worse premenstrual pain than normal in women

What are some effects of manganese on health?

Scientists are studying manganese to understand how it affects health. Here are some examples of what this research has shown.

Bone health

You need manganese in combination with other minerals and vitamins for healthy bone formation. But more research is needed to understand the role of manganese in maintaining or improving bone health.

Diabetes

You need manganese to help break down the starches and sugars that you eat. But its effect on the risk of diabetes is unknown. More research is needed to understand whether manganese plays a role in the development of diabetes.

Can manganese be harmful?

Studies have not shown any harm from the manganese in food and beverages. But some people have developed manganese toxicity by consuming water containing very high levels of manganese. Another cause of manganese toxicity is inhaling large amounts of manganese dust from welding or mining work.

The symptoms of manganese toxicity include tremors, muscle spasms, hearing problems, mania, insomnia, depression, loss of appetite, headaches, irritability, weakness, and mood changes.

People should not consume more manganese than the upper limits from food, beverages, or dietary supplements unless their health care provider recommends doing this.

The daily upper limits for manganese include intakes from all sources—food, beverages, and supplements—and are listed below.

Does manganese interact with medications or other dietary supplements?

Manganese is not known to interact or interfere with any medicines.

Tell your doctor, pharmacist, and other health care providers about any dietary supplements and prescription or over-the-counter medicines you take. They can tell you if the dietary supplements might interact with your medicines or if the medicines might interfere with how your body absorbs, uses, or breaks down nutrients, such as manganese.

Manganese and healthful eating

People should get most of their nutrients from food and beverages, according to the federal government’s Dietary Guidelines for Americans. Foods contain vitamins, minerals, dietary fiber, and other components that benefit health. In some cases, fortified foods and dietary supplements are useful when it is not possible to meet needs for one or more nutrients (for example, during specific life stages such as pregnancy). For more information about building a healthy dietary pattern, see the Dietary Guidelines for Americans and the U.S. Department of Agriculture’s MyPlate.

Where can I find out more about manganese?

• For more information about manganese:
  • Office of Dietary Supplements Health Professional Fact Sheet on Manganese

• For more information on food sources of manganese:
  • USDA, FoodData Central

• For advice on choosing dietary supplements:
  • Office of Dietary Supplements, Frequently Asked Questions: Which brand(s) of dietary supplements should I purchase?

• For information about building a healthy dietary pattern:
  • MyPlate
  • Dietary Guidelines for Americans

Disclaimer

This fact sheet by the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) provides information that should not take the place of medical advice. We encourage you to talk to your health care providers (doctor, registered dietitian, pharmacist, etc.) about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. Any mention in this publication of a specific product or service, or recommendation from an organization or professional society, does not represent an endorsement by ODS of that product, service, or expert advice.

Updated:
March 22, 2021
History of changes to this fact sheet

Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Manganese is an essential mineral required for the body to function properly. It’s found in foods such as nuts, whole grains, and leafy green vegetables.

Manganese is the twelfth most common element on the earth’s crust. In the body, it’s involved in many chemical processes, including the processing of cholesterol, carbohydrates, and protein. It might also be involved in bone formation.

People use manganese for manganese deficiency. It is also used for hay fever, osteoporosis, osteoarthritis, wound healing, and many other conditions, but there is no good scientific evidence to support these uses.

Uses & Effectiveness ?

Effective for

• Manganese deficiency. Taking manganese by mouth or by IV can treat or prevent low manganese levels in the body. IV products can only be given by a healthcare provider.

There is interest in using manganese for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Manganese is likely safe for adults 19 years and older when consumed in amounts up to 11 mg daily. But taking more than 11 mg daily by mouth is possibly unsafe. Taking high doses, long-term can lead to Parkinson disease-like symptoms.

When inhaled: Manganese is likely unsafe when used in moderate amounts, long-term. Excess manganese in the body can cause serious side effects, including poor bone health and symptoms similar to Parkinson disease, such as tremors.

Special Precautions and Warnings

When taken by mouth: Manganese is likely safe for adults 19 years and older when consumed in amounts up to 11 mg daily. But taking more than 11 mg daily by mouth is possibly unsafe. Taking high doses, long-term can lead to Parkinson disease-like symptoms.

When inhaled: Manganese is likely unsafe when used in moderate amounts, long-term. Excess manganese in the body can cause serious side effects, including poor bone health and symptoms similar to Parkinson disease, such as tremors.

Children: Taking manganese by mouth is likely safe for children when consumed in amounts below the daily tolerable upper intake level (UL) by age: less than 2 mg for those 1-3 years; less than 3 mg for those 4-8 years; less than 6 mg for those 9-13 years; and less than 9 mg for those 14-18 years. Taking higher doses is possibly unsafe. Manganese is also likely unsafe when inhaled by children.

Pregnancy and breast-feeding: Manganese is likely safe when taken by mouth while pregnant or breast-feeding in doses below the tolerable upper intake level (UL). This means less than 11 mg daily for those 19 years and older and less than 9 mg daily in those under 19 years-old. Manganese is possibly unsafe when taken by mouth in higher doses. Doses over 11 mg daily are more likely to cause serious side effects. Taking too much manganese might also decrease the birth size of male infants. Manganese is likely unsafe when inhaled while pregnant or breast-feeding.

Liver disease: People with long-term liver disease have trouble getting rid of manganese. Manganese can build up and cause side effects. If you have liver disease, be careful not to get too much manganese.

Iron-deficiency anemia: People with iron-deficiency anemia seem to absorb more manganese than other people. If you have this condition, be careful not to get too much manganese.

Interactions ?

Moderate Interaction

Be cautious with this combination

• Manganese can attach to quinolone antibiotics in the stomach, decreasing the amount of antibiotics that can be absorbed by the body. This might decrease their effects. To avoid this interaction, take manganese supplements at least one hour after quinolone antibiotics.

• Manganese can attach to tetracycline antibiotics in the stomach, decreasing the amount of antibiotics that can be absorbed by the body. This might decrease their effects. To avoid this interaction, take manganese two hours before or four hours after taking tetracyclines.

• Taking certain antipsychotic drugs along with manganese might worsen side effects of manganese in some people.

Dosing

It’s recommended that adult males 19 years and older consume 2.3 mg of manganese daily and adult females 19 years and older consume 1.8 mg of manganese daily.

As medicine, manganese has most often been used by adults in combination with other ingredients, in doses of 0.5-5.6 mg by mouth daily for up to 24 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.

View References

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

Effect of manganese on the human body: harm or benefit?

The effect of manganese on the human body: harm or benefit? | BWT

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The effect of manganese on the human body: harm or benefit?

Article

08/27/2020

Everyone has long known such a metal as manganese. Most often, this element accompanies the gland, but can also occur independently. It is the second most common metal, and the second among the heavy ones. It is found in water and food, so it is necessary to know the effect of manganese on the human body. This trace element is necessary for everyone, it plays a significant role in life, namely, it has a direct impact on growth, the functioning of the sex glands and blood formation.

Nevertheless, the effect of manganese on the human body is twofold: both positive and negative. Heavy metals enter the body daily with water, which an adult needs to drink up to 2 liters per day. When preparing soup or enjoying morning coffee, we can cause irreparable harm to ourselves if the water contains impurities. Removing iron and manganese from water is an important step in water treatment.

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The negative effect of manganese primarily affects the functioning of the central nervous system. Its excessive accumulation manifests itself in the form of constant drowsiness, memory impairment, increased fatigue. Manganese is a polytropic poison that has a harmful effect on the functioning of the lungs, the cardiovascular system, and can cause an allergic or mutagenic effect.

The dose leading to manganese poisoning is 40 mg per day, there is a decrease in appetite, growth inhibition, impaired iron metabolism and brain function. However, the most severe consequences for the body are systematic heavy metal poisoning.

The daily requirement for manganese depends on age. An adult needs from 2.5 to 5 mg, children up to a year 1 mg, from 1 year to 15 – 2 mg. Manganese enters the human body with plant and animal food. Most of all it is found in beef liver, meat, milk and dairy products, pineapples, cereals, black currants, rose hips, legumes, beet leaves and carrots.

Manganese enters the human body with water. Sanitary and epidemiological standards regulate its content in drinking water, which is 0.1 mg / l. This is significantly more than in Europe, where 0.05 mg/l is considered acceptable. It is reassuring that, according to the World Health Organization, it is believed that the content of manganese in water at a dose of 0.5 mg / l does not adversely affect the human body. Exceeding the norm leads to its accumulation and to the disease of the skeletal system.

At home, it is easy to determine the presence of manganese in water by its astringent taste and yellowish color; black or dark brown coating becomes noticeable on the pipes. In the water of a cloudy dark color, a black precipitate may fall out, and with prolonged contact with such water, the skin of the hand and nail plates darken. Therefore, it is necessary to pay special attention to the choice of a water purification system for the home.

Manganese tends to accumulate and clog water pipes, but pipes can be changed. In the human body, an excess amount of metals accumulates in the liver, which cannot be changed. The effect of manganese on the human body is very negative, but it cannot be the only cause of serious diseases, but it is quite within its power to significantly worsen the course of others. You need to take care of your health right now. Therefore, it is better to prevent diseases than to spend money on treatment later.

If you do not want to entrust your health and the health of your family to public utilities, it is time to think about water filtration installations. They have a wide price range and are available for sale in stores and on websites. For industrial purposes, the content of manganese in water can also be strictly limited; industrial filters for iron removal and demanganization have a high throughput and several degrees of purification. If you want to drink clean water and benefit from it, you need to take matters into your own hands and purchase filtration systems.

A jug filter is also suitable for home use, its main drawback is that it is able to process a small amount of water. If you want to approach the problem of water purification thoroughly, it is better to purchase membrane or reverse osmosis filtration units that can neutralize the negative effects of manganese and other heavy metals on the body.

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Manganese – ingredient description, instructions for use, indications and contraindications0002 7565

ProWellness

Table of contents

• Description of manganese
• Functions of manganese
• Effects on the body ganza
• Application

Disclaimer

Please note that all information posted on the site
Prowellness is provided for informational purposes only and is not a personal program, a direct recommendation for action, or medical advice. Do not use these materials for diagnosis, treatment, or any medical procedure. Consult your physician before using any technique or using any product. This site is not a specialized medical portal and does not replace the professional advice of a specialist. The Site Owner is not liable to any party who has suffered indirect or direct damage as a result of misuse of materials posted on this resource.

Description of manganese

Manganese is a white-silver metal, an important microelement for human health. It is present in the kidneys, liver, brain cells and bones, pancreatic tissues. Its deficiency negatively affects the state of all organs and systems.

Functions of manganese

• Regulation of blood glucose levels.
• Maintaining healthy bones.
• Regulation of the activity of metabolic processes.
• Formation of connective tissues.
• Strengthening of the arteries.
• Normalization of the functioning of the thyroid gland.
• Normalization of the reproductive system.
• Relief of premenstrual syndrome.
• Absorption of calcium, copper, choline, vitamins C, B, A.
• Collagen formation.
• Normalization of the central nervous system.
• Weight normalization.
• Antioxidant protection.

Effects on the body

Manganese helps to reduce bone loss, so the elderly should definitely include supplements with this trace element in their diet.

Manganese affects the functioning of the nervous system. It is involved in the synthesis of neurotransmitters that transmit nerve impulses.

The trace element has a positive effect on the formation and growth of bone tissue, normalizes digestion, and increases the body’s ability to resist infections. With its deficiency in the body, it is impossible to absorb calcium, copper, choline, vitamins C, B, A.

Manganese is needed for brain function, tissue regeneration, formation of new cells. It reduces the risk of developing diabetes, diseases of the thyroid gland, heart, blood vessels.

The element restores muscle tone, prevents atherosclerosis, lowers the activity of low-density lipoproteins, that is, “bad” cholesterol.

Manganese is important for the proper development of the fetus during pregnancy. In addition, it promotes lactation after childbirth.

Attention! The body’s daily requirement for manganese depends on lifestyle and age. It can be determined by the formula: 0.2 mg per 1 kg of weight.

Manganese deficiency

Manganese deficiency leads to anemia, chronic fatigue, growth retardation, decreased visual acuity, pigmentation, rashes, testicular and ovarian atrophy, decreased bone strength, memory impairment, decreased immunity.

An excess of manganese

An overdose of manganese is possible when taking high doses of drugs and drinking tap water. If cloudy water flows from the tap, giving a precipitate, it is most likely saturated with minerals – it is worth installing a high-quality filtration system.

Attention! An excess of manganese is accompanied by lack of appetite, insomnia, sexual dysfunction, drowsiness, back pain, hallucinations, urinary disorders.

Food sources of manganese

Manganese is rich in plant products: olive oil, herbs, grapes, cabbage, carrots, peas, cereals, berries, honey, cocoa, nuts. A high concentration of the mineral is possible only in natural products that are not subjected to heat treatment.

A small amount of manganese is present in some animal products: meat, kidneys, fish, crustaceans. But with their help it is impossible to make up for its deficiency.

Application

Manganese supplements should not be taken by people with Parkinson’s disease and those whose professional activities involve the use of manganese salts.