Ms flare: The request could not be satisfied
MS flare-ups require quick, personalized treatment
When you get diagnosed with a serious disease, you have a lot of questions.
“How will this affect my life?”
“How will this affect my family?”
“What comes next?”
But when faced with a diagnosis of multiple sclerosis, the answers to those questions can be complicated because the disease affects each person differently.
Multiple sclerosis, or MS, is an autoimmune disease that attacks the protective sheath that covers nerves. And it manifests in many different ways – including numbness, pain, fatigue, slurred speech or loss of vision – depending on which nerves are most affected.
“Each case is so different. It’s not comparable to something like a fracture, where you can say, ‘This is your recovery, and these are the steps you can take in order to get as much strength or function back as you can,’” said Alaine Robinson, supervisor of the MS Clinic at OSF HealthCare Illinois Neurological Institute.
An unpredictable disease
While some people have progressive MS – a form of the disease in which symptoms intensify over time – most people have what’s called a relapsing-remitting disease course. They can have weeks, months or years with little to no symptoms, interrupted by “flare-ups” of the disease.
These flare-ups, also called attacks or exacerbations, can come on suddenly, and no two are alike. One episode might be the onset of optic neuritis, or inflammation of the optic nerve causing changes in vision, while the next might bring difficulty chewing and swallowing.
“Exacerbations can be brought on by a multitude of things. It can be an infection or even a life stressor,” Alaine said.
Because of the disease’s tendency to affect so many different body parts and functions, symptom management can be complex.
A comprehensive MS Center, OSF INI has implemented new processes to respond to the sudden onset of symptoms as quickly as possible.
Specialized MS care
Led by three fellowship-trained MS specialists, the MS Center developed guidelines so nurses or navigators can start the process for changing or ordering new medications as quickly as possible.
They’ll even contact a person’s insurance provider directly to get authorization for the medication before they even come into the clinic.
They’ve also integrated multiple medical disciplines into their comprehensive MS exams, giving patients with uncontrolled symptoms one place to access all of the resources they need in a single appointment.
“You’re not just seeing your MS provider. You’re seeing physical, occupational or speech therapy; you’re seeing dietitian, social worker and a psychotherapist. We also work closely with our neuro-ophthalmologists and neuro-immunologists,” Alaine said.
With navigators to help with insurance or financial hardships and an MS Fund for charitable support, the team at OSF INI is committed to providing for each person’s unique needs.
“We want you to know that we’re here to support you, whatever you need,” Alaine said.
Multiple Sclerosis (MS) | Patient
What is multiple sclerosis?
Multiple sclerosis (MS) is a disease where patches of inflammation occur in parts of your brain and/or spinal cord.
This can cause damage to parts of your brain and lead to various symptoms (described below).
Understanding the brain, spinal cord, and nerves
Many thousands of nerve fibres transmit tiny electrical messages (impulses) between different parts of your brain and spinal cord. Each nerve fibre in the brain and spinal cord is surrounded by a protective sheath made from a substance called myelin. The myelin sheath acts like the insulation around an electrical wire. It is needed for the electrical impulses to travel correctly along your nerve fibres.
Nerves are made up from many nerve fibres. Nerves come out of your brain and spinal cord and take messages to and from your muscles, skin, body organs and tissues.
Multiple sclerosis causes
MS is thought to be an autoimmune disease. This means that cells of the immune system, which normally attack germs (bacteria, viruses, etc), attack part of your body. When the disease is active, parts of your immune system, mainly cells called T cells, attack the myelin sheath which surrounds your nerve fibres in the brain and spinal cord.
This leads to small patches of inflammation.
Something may trigger your immune system to act in this way. One theory is that a virus or another factor in the environment triggers your immune system if you have a certain genetic makeup. Your genetic makeup is the material inherited from your parents which controls various aspects of your body.
The inflammation around the myelin sheath stops the affected nerve fibres from working properly and symptoms develop. When the inflammation clears, the myelin sheath may heal and repair and nerve fibres start to work again. However, the inflammation, or repeated bouts of inflammation, can leave a small scar (sclerosis) which can permanently damage nerve fibres. In a typical person with MS, many (multiple) small areas of scarring develop in the brain and spinal cord. These scars may also be called plaques.
How does multiple sclerosis progress?
Once the disease is triggered, it tends to follow one of the following four patterns.
Relapsing-remitting form of MS
Nearly 9 in 10 people with MS have the common relapsing-remitting form of the disease. In a relapse, an attack (episode) of symptoms occurs. During a relapse, symptoms develop (described below) and may last for days but usually last for 2-6 weeks. They sometimes last for several months. Symptoms then ease or go away (remit). You are said to be in remission when symptoms have eased or gone away. Further relapses then occur from time to time.
The type and number of symptoms that occur during a relapse vary from person to person, depending on where myelin damage occurs. The frequency of relapses also varies. Having one or two relapses every two years is fairly typical. However, relapses can occur more or less often than this. When a relapse occurs, previous symptoms may return, or new ones may appear.
This relapsing-remitting pattern tends to last for several years. At first, full recovery from symptoms, or nearly full recovery, is typical following each relapse.
In time, in addition to myelin damage, there may also be damage to the nerve fibres themselves.
Eventually, often after 5-15 years, some symptoms usually become permanent. The permanent symptoms are due to accumulation of scar tissue in the brain and to the gradual nerve damage that occurs. The condition typically then slowly becomes worse over time. This is called secondary progressive MS. Typically, about two thirds of people with relapsing-remitting MS will have developed secondary progressive MS after 15 years.
Secondary progressive form of MS
There is a steady worsening of your symptoms (with or without relapses) in this form of MS. Many people with the relapsing-remitting form later develop this type of MS.
Primary progressive form of MS
In about 1 in 10 people with MS, there is no initial relapsing-remitting course. The symptoms become gradually worse from the outset and do not recover. This is called primary progressive MS.
Benign MS
In less than 1 in 10 people with MS, there are only a few relapses in a lifetime and no symptoms remain permanent.
This is the least serious form of the disease and is called benign MS.
Who gets multiple sclerosis?
About 1 in 500 people in the UK develop MS. It can affect anyone at any age, although it is rare in young children. It often first develops in people aged between 30 and 50. MS is the most common disabling illness of young adults in the UK. It is more than twice as common in women as in men.
MS is not strictly an hereditary disease. However, you have an increased chance of MS developing if you have a close relative with MS. For example, if your mother, father, brother or sister has MS, then you have about a 2 in 100 chance of developing MS (compared with about a 1 in 500 chance in the general population).
Multiple sclerosis symptoms
MS causes a wide variety of symptoms. Many people experience only a few symptoms and it is very unlikely that you would develop all the symptoms described here if you have MS. Symptoms of MS are usually unpredictable.
You may find that your symptoms worsen gradually with time.
More commonly, symptoms come and go at different times. Periods when your symptoms worsen are called relapses. Periods when your symptoms improve (or even disappear altogether) are called remissions.
Relapses can occur at any time and your symptoms may differ within each relapse. Although relapses usually occur for no apparent reason, various triggers can include infections, exercise and even hot weather. The symptoms that occur during a relapse depend on which part, or parts, of your brain or spinal cord are affected. You may have just one symptom in one part of your body, or several symptoms in different parts of your body. The symptoms occur because the affected nerve fibres stop working properly.
The more common symptoms include:
Visual problems
The first symptom of MS for around one in four people with MS is a disturbance of vision. Inflammation (swelling) of the optic nerve can occur. This is called optic neuritis. This can cause pain behind your eye and also some loss of your vision.
This usually only affects one eye. Other eye symptoms may include blurring of your vision or having double vision.
Muscle spasms and spasticity
Tremors or spasms of some of your muscles may occur. This is usually due to damage to the nerves that supply these muscles. Some muscles may shorten (contract) tightly and can then become stiff and harder to use. This is called spasticity.
Pain
There are two main types of pain that may occur in people with MS:
- Neuropathic pain – this occurs due to damage to the nerve fibres. This can cause stabbing pains or a burning sensation over parts of your skin. Areas of your skin may also become very sensitive.
- Musculoskeletal pain – this type of pain can occur in any of your muscles that are affected by spasms or spasticity.
Fatigue
Extreme tiredness (fatigue) is one of the most common symptoms of MS. This tiredness is more than the tiredness you would expect after exercising or exertion.
This fatigue can even affect your balance and concentration. There are different treatments for fatigue which are often a combination of self-management strategies, physiotherapy and exercise.
Emotional problems and depression
You may find that you laugh or cry more easily, even for no reason. Also, many people with MS have symptoms of depression or anxiety at some stage. It is important to see your doctor and talk about any of these symptoms you may have. Treatment for depression and anxiety is often effective.
Other symptoms which may occur include:
- Numbness or tingling in parts of your skin. This is the most common symptom of a first relapse.
- Weakness or paralysis of some muscles. Your mobility may be affected.
- Problems with your balance and co-ordination.
- Problems with your concentration and attention.
- Tremors or spasms of some of your muscles.
- Dizziness.
- Problems with passing urine.
- In men, inability to have an erection.
- Difficulty with speaking.
Secondary symptoms
These are symptoms that may develop later in the course of the disease when some of the above symptoms become permanent. They may include contractures, urine infections, ‘thinning’ of your bones (osteoporosis), muscle wasting and reduced mobility.
Multiple sclerosis diagnosis
Almost all the symptoms that can occur with MS can also occur with other diseases. It is often difficult to be sure if a first episode of symptoms (a first relapse) is due to MS. For example, you may have an episode of numbness in a leg, or blurring of vision for a few weeks, which then goes. It may have been the first relapse of MS or just a one-off illness that was not MS.
Therefore, a firm diagnosis of MS is often not made until two or more relapses have occurred. So, you may have months, or years, of uncertainty if you have an episode of symptoms and the diagnosis is not clear.
Do any tests help?
In most cases, no test can definitely prove that you have MS after a first episode of symptoms or in the very early stages of the disease.
However, some tests are helpful and may indicate that MS is a possible, or probable, cause of the symptoms.
A magnetic resonance imaging (MRI) scan of the brain is a useful test. This type of scan can detect small areas of inflammation and scarring in your brain which occur in MS. Although very useful in helping to make a diagnosis of MS, MRI scans are not always conclusive, especially in the early stages of the disease. A scan result should always be viewed together with your symptoms and physical examination.
Since MRI scans became available, other tests are now done less often. However, they are sometimes done and include:
- Lumbar puncture. In this test a needle is inserted, under local anaesthetic, into the lower part of your back. It takes a sample of some of the fluid that surrounds your brain and spinal cord. This is called cerebrospinal fluid (CSF). Certain protein levels are measured. Some proteins are altered in MS, although they can be altered in other conditions too.
- Evoked potential test. In this test, electrodes measure if there is slowing or any abnormal pattern in the electrical impulses in certain nerves.
Multiple sclerosis treatment
At present, although there is no cure for MS, certain symptoms of MS can often be eased. Treatments generally fall into four categories:
- Medicines that aim to modify the disease process.
- Steroid medication to treat relapses.
- Other medicines to help ease your symptoms.
- Other therapies and general support to minimise disability.
Medicines that aim to modify the disease process
These medicines are known as immunomodulatory agents. They include interferon beta, glatiramer, dimethyl fumarate, teriflunomide, alemtuzumab, natalizumab and fingolimod. These medicines do not cure MS and they are not suitable for everyone with MS. Natalizumab is a newer treatment for patients with more advanced and very active MS. Fingolimod, teriflunomide and dimethyl fumarate are the only tablet forms of disease-modifying treatment.
All the others are given by injection.
Studies have shown that these medicines reduce the number of relapses in some cases. They may also have a small effect on slowing the progression of the disease. The exact way in which they work is not clear but they all interfere with the immune system in some way.
As there is still some uncertainty as to the role of these medicines and how effective they are, guidelines have been drawn up by the Association of British Neurologists as to when they may be prescribed on the NHS. A specialist (neurologist) will advise on whether one of the treatments is recommended for you. If you are prescribed any of these treatments you will be closely monitored. With the help of this monitoring, over time, it should become clear how effective the treatments are.
Each of the different disease-modifying medicines has pros and cons. The Multiple Sclerosis Trust (see under ‘Further Reading’, below) provides an MS Decisions page which is designed to help you decide which is the best medicine for you.
Newer medicines and combinations of medicines are also being studied.
Steroids (sometimes called corticosteroids)
A steroid is often prescribed if you have a relapse which causes disability. A high dose is usually given for a few days. Sometimes steroid tablets are used or the steroid may be given through your veins. The steroids work by reducing inflammation. A course of steroids will usually shorten the duration of a relapse. This means that your symptoms usually improve more quickly than they would otherwise have done.
However, steroids do not affect the ongoing progression of the disease.
Other treatments to improve symptoms
Depending on the symptoms that you develop, other treatments may be advised to combat the symptoms. For example:
Other treatments, therapies and support
A range of therapies may be advised, depending on what problems or disabilities you develop. They include:
- Physiotherapy.
- Occupational therapy.
- Speech therapy.
- Specialist nurse advice and support.
- Psychological therapies.
- Counselling.
Multiple sclerosis prognosis
MS affects different people in many different ways. This means that it is very difficult to predict your outlook (prognosis) if you have MS. There are currently no tests to predict how your MS will progress.
Most people with MS will be able to continue to walk and function at their work for many years after their diagnosis. The majority of people diagnosed with MS will not need to use a wheelchair on a regular basis.
However, some people with MS do become disabled over time, and a minority become severely disabled.
The treatment of MS is a rapidly developing area of medicine. The research into newer and better disease-modifying treatments brings a great deal of hope that the outlook for people with MS will continue to improve in the future. The specialist who knows your case can give more accurate information about the outlook for your particular situation.
What to do if you are having an MS flare up or relapse |
What to do if you are having an MS flare up or relapse
Posted on 4 February 2019 in Managing Relapses
If you think you are having a relapse, your best option is to contact your MS team (MS nurse or neurologist) as soon as possible and ask for advice.
Why?
- To help in confirming whether this is a relapse and if significant, you might need to consider treatment sooner rather than later.
- Document your symptoms and to consider whether you need to start or switch your disease modifying therapy (DMT).
- The MS team has the complex needed skills while other healthcare professionals rarely manage a reasonable number of PwMS to maintain the required expertise.
Alternatively,
you might need to contact your GP or other available healthcare professionals.
MS
relapse is also
known as exacerbation, attack, an episode, a blip or a flare-up. It causes relatively sudden
(over hours or days) new
symptoms or worsening of old symptoms. It can be very mild, or severe enough to
interfere with a person’s ability to function at home and at work.
It is
interesting to note that there is some seasonal variation in the incidence of
MS relapses, with the incidence peak in spring and trough in winter!
Source: multiplesclerosis.net/living-with-ms/multiple-sclerosis-relapses/
To be true, a relapse must:
- last at least 24 hours
- be separated from the previous attack by at
least 30 days - there must be no other explanation for the
symptoms
The other possible explanations might cause symptoms that
simulate an MS relapse, usually referred to as “Pseudo-relapse”, these
include:
It is important to recognise a pseudo-relapse as it is not
caused by inflammation or worsening of your MS and does not need consideration
of immune therapy or alteration to your existing DMT.
Repeated worsening of similar pattern of symptoms (stereotyped)
in a PwMS is not a typical feature for MS relapses and raises suspicion of
pseudo-relapses.
If you are not sure whether you are having a relapse, one
option is to wait 1-2 days to see if your symptoms improve. If you have MS for
a while, you are likely had become an expert on your own MS and you have a
better feel for whether or not you are having a relapse.
Most relapses last from a few days to several weeks or occasionally
months. The good news is that not all relapses require treatment. Mild sensory symptoms
or more of fatigue that don’t significantly impact a person’s activities can
generally be left to get better on its own.
For moderate and severe relapses like loss of vision, significant
weakness or poor balance, it is generally recommended to consider a short
course of high-dose corticosteroids to reduce the inflammation and bring the symptoms
to an end more quickly.
The most common treatment regimen is a five-day course of oral methylprednisolone; occasionally IV methylprednisolone infusion is recommended for 3-5 days as per NICE MS Guideline.
Your MS team should discuss with you the pros and cons of
taking steroids so that you can decide together on the best course of action in
your situation. Corticosteroids use for a relapse does not have any long-term
benefit on your MS.
It is highly recommended not to use other types of steroids
for MS relapses and not to use a course longer than the recommended few days.
This practice is still not rare in the UK and abroad!
Rest can be useful during a relapse when fatigue is
overwhelming.
Rehabilitation can restore or maintain functions essential
to daily living especially immediately after a relapse to help people get back
on track. Ask your MS team whether this might be useful to you.
What can
I do to reduce my risk of having a relapse?
- Avoid excessive or prolonged stress
and try to manage early - Reduce your risk of infections by
flu vaccination, for example or by managing your urinary symptoms to avoid
recurrent UTIs. - Maintain healthy life-style:
balanced diet, regular exercise and avoid smoking can also reduce your
infections risk - Adhere to your DMT if you were missing
it previously. - Consider DMTs when your MS team
advise you and re-consider if you were reluctant to use these medications in
the past.
From my personal experience at the Royal Stoke MS Centre in the last few years, we are probably treating a smaller number of relapses and a smaller number of severe relapses than before in spite of increasing size of our MS cohort and better access to our On-Call MS Team. This is probably due to more use of the highly effective DMTs. This is not surprising but needs confirmation by an appropriate study.
Useful sources of further information
- MS Trust website: Managing relapses
- MS Society website: Managing relapses
- BMJ article: Relapse in multiple sclerosis
- Systematic review
Dr Adnan Al-Araji, Consultant MS Neurologist
New evidence of gut-brain mechanism involved in MS flare-ups
New research, led by a team from UC San Francisco, has shown how immune cells produced in the gut play a protective role during multiple sclerosis (MS) flare-ups.
For the first time, scientists have shown how these immune cells travel up to the brain and potentially help shift a disease flare-up into remission.
A groundbreaking study published early in 2019 described how a specific kind of immune antibody, called Immunoglobulin A (IgA), was measured in low levels from fecal samples of MS patients suffering active neuroinflammation. This earlier study also found that increasing the volume of these IgA cells in mouse models resulted in a resistance to MS-related brain inflammation.
IgA antibodies are mostly produced by cells in the intestine, and the new hypothesis raised by the 2019 study was that MS-related brain inflammation can be, to a degree, modulated by a mechanism that originates in the gut. Now a new study, led by the same team and published in Science Immunology, has moved beyond animal models to show these gut immune cells are indeed present in human MS patients during disease flare-ups.
The new research looked for these gut IgA antibodies in cerebrospinal fluid from MS patients.
The findings confirmed the cells were present in spinal fluid, but only during flare-ups and not when the disease was in remission.
This suggests these immune cells originating in the gut certainly play a role in MS flare-ups. The next question the researchers set out to answer was whether these immune cells help tamper down a flare-up or actively contribute to disease activity.
Investigating how these particular IgA antibodies respond to other molecules, the researchers found they do not bind to myelin protein. This meant the antibodies do not play a direct role in damaging brain cells. Instead, the researchers discovered these IgA cells are more interested in attacking harmful bacteria.
One hypothesis presented in the study is that these immune cells are produced in the gut in response to harmful bacteria. The immune agents then chase the harmful bacteria throughout the body, and end up mounting a defense in the brain.
So why haven’t these relatively common immune cells ever been associated with MS before now? Sergio Baranzini, lead author on the new study, suggests two reasons.
“It was a very new idea,” he says. “Nobody thought to look for this type of immune cell. Only at the time of an attack was there an increase in these cells and the antibodies they produce. That really caught our attention.”
What this new study means is that a whole new line of research can now explore novel ways to therapeutically modulate this gut-brain immune pathway. Altered gut bacterial populations have previously been linked to MS but no single bacterium, or broader microbiome profile, has been directly associated with disease progression.
Not only could these IgA cells be used as an effective biomarker for acute disease activity in the future, but the new study offers more evidence of the bidirectional gut-brain axis with implications not just for MS treatment but many other brain diseases characterized by neuroinflammation.
The new study was published in the journal Science Immunology.
Source: UC San Francisco
MS Flare-Ups and Managing Relapses
Multiple sclerosis (MS) damages the myelin sheath that coats neurons (nerve cells) within the brain and spinal cord, collectively known as the central nervous system..png)
This damage causes symptoms such as vision problems, weakness, numbness, imbalance, spasticity, and bowel or bladder dysfunction. As MS progresses, its symptoms and their severity can fluctuate based on several factors.
Symptom fluctuations may or may not be an MS relapse. MyMSTeam sat down with Dr. Jacqueline Nicholas to find out more about MS relapses — what causes them and how to manage them. Dr. Nicholas is a board-certified neurologist specializing in neuroimmunology, MS, and spasticity. She currently serves as the system chief of neuroimmunology and multiple sclerosis, the director of MS research, and the neuroimmunology fellowship director at the OhioHealth Multiple Sclerosis Clinic in Columbus, Ohio.
What Is a Relapse?
Relapses are often referred to as attacks, exacerbations, or flares. Most people living with MS will experience a relapse at some point. However, a relapse is not the same thing as the standard progression of MS. According to Dr.
Nicholas, “When we use the term progression, we usually think of something that is slowly worsening over a long period of time, separate from relapses.”
An exacerbation is a worsening of MS symptoms or the onset of new MS symptoms that last more than 24 hours and are not due to fever, infection, or overheating. Symptoms of a relapse typically develop over hours to days.
Symptoms of a relapse vary from person to person. No two exacerbations are alike. How often and how severe a relapse will be is unpredictable. One MyMSTeam member described their MS flare-up: “I will not be able to sleep for a few nights. I get very cold when normally I am always hot. My stiffness in my legs and back start getting bad. It will feel like I am getting the flu. Then it gets worse, and I have trouble with balance and sometimes can’t walk.”
A true MS exacerbation will have these characteristics:
- The flare must include new symptoms or a worsening of old symptoms.
- The attack must last at least 24 hours.
- The episode cannot occur within 30 days of the last flare-up.
- There cannot be another cause for the exacerbation, such as an infection, fever, or temperature extremes (usually hot weather).
What Causes MS Flare-Ups?
Relapses are caused by inflammation which results in damage to the myelin coating on neurons within the brain or spinal cord. Most exacerbations occur for a few days at a time. Recovery from a relapse can be complete, partial, or without any improvement. Most people recover from a relapse within two to three months of onset. In general, the full degree to which an individual will recover from a single relapse may take up to one year. That’s not to say that there won’t be improvement sooner, but the majority of the improvement would occur within one year.
Common symptoms of an MS flare include fatigue, dizziness, balance and coordination issues, weakness in a leg or arm, muscle spasms, difficulties remembering and concentrating, and areas of numbness, pain, or tingling.
Vision issues, particularly optic neuritis, may also point to an MS flare. “Optic neuritis is a common relapse symptom in the setting of MS,” Dr. Nicholas explained.
What Is a Pseudo-Relapse?
A pseudo-relapse or pseudo-exacerbation is a temporary worsening of prior or chronic symptoms. It can seem like a relapse, but it isn’t. A pseudo-relapse is not caused by an uptick in disease activity. In other words, it is not accompanied by inflammation or new brain or spinal cord damage.
A pseudo-exacerbation is usually caused by an external factor, such as excessive heat or stress. A pseudo-flare can also be caused by an infection, such as a urinary tract infection (UTI), or a cold or flu. The most common cause of pseudo-relapse is UTI. For this reason, when doctors are evaluating people with MS for a possible relapse, they often screen for a UTI.
To differentiate between a relapse and a pseudo-relapse, it’s important to determine whether or not the person has a fever. Even a mild infection or the smallest body temperature increase can trigger symptoms.
“When I am tired, hot, or stressed, I will have a pseudo-flare,” said a MyMSTeam member. “Once I am cool, calm, and collected, my symptoms go away.” Most pseudo-flares resolve within 24 hours after the underlying cause of the exacerbation is resolved.
Why Do Relapses Occur?
Exacerbations are caused by inflammation in the central nervous system. Inflammation damages the myelin on neurons within the brain and spinal cord, also known as demyelination. Demyelination and inflammation interrupt the flow of signals traveling along neurons. The location of inflammation or damage determines which symptoms of MS develop. Sometimes, inflammation may cause no symptoms at all. This is why health care professionals recommended individuals with MS be monitored for silent disease activity with magnetic resonance imaging (MRI) scans.
One can experience just one symptom or many symptoms together during a relapse. When the inflammation impacts a single area of the central nervous system, relapses typically produce only one neurologic symptom — for example, numbness in one leg. Other times relapses cause a person to experience several symptoms simultaneously — for instance, muscle weakness and vision changes. This usually happens when the inflammation occurs in more than one part of the brain or spinal cord.
What Do Relapses Indicate?
No evidence of disease activity (NEDA) is an emerging goal of MS treatment. Breakthrough flares (flares that occur during treatment with a disease-modifying therapy) can be an indication that a person’s disease is becoming more active. A breakthrough flare may indicate that it’s time to consider starting or switching to a new MS treatment. But not all relapses mean a treatment regimen has stopped working.
Drug therapies for MS need time to take effect. “If somebody just started treatment maybe a month ago and they had a relapse, it’s possible that that treatment just hasn’t had enough time to get into the system and have its full effect,” explained Dr. Nicholas. “With each disease-modifying therapy, for the most part, they take about six months to give their full benefit.”
The good news is that there are multiple treatment options available to prevent new relapses and new lesions in MS. “Typically, we would pick something that we believe, in our experience and based on clinical trials, is more effective than the one that the individual had a breakthrough on,” said Dr. Nicholas.
Learn more about available treatments for MS.
What Types of MS Feature Relapses?
In relapsing-remitting multiple sclerosis (RRMS), relapses can occur throughout the span of the disease. Remission is a confusing term because in some conditions, such as cancers, remission typically refers to the absence of disease. Even when MS is considered to be in a phase of remission — not in an active relapse — MS can still cause silent damage in the brain and spine. These bouts of relapse and remission can last days, weeks, or months. Approximately 85 percent of people with MS are diagnosed with RRMS, the most common form of MS.
In RRMS, the time between relapse and remission varies. One study found people with RRMS had a relapse on average once every two years. Sometimes they’re more frequent; in other cases, less frequent. Generally speaking, exacerbations tend to happen more often during the years right after diagnosis, but people with MS can experience a relapse at any time.
“One way to significantly reduce the chance of having an MS relapse is to take a disease-modifying therapy (DMT) for multiple sclerosis,” said Dr. Nicholas. “There are many options which are proven to reduce the risk of relapse.”
People with secondary progressive multiple sclerosis (SPMS) can experience relapses, but much less frequently. People diagnosed with primary progressive multiple sclerosis (PPMS) often experience fluctuations in how they feel from one day to the next, but by definition, they do not experience relapses. Dr. Nicholas explained, “There are rare individuals with who’ve been believed to have primary progressive MS who then can have a subsequent relapse. We call that progressive relapsing MS.”
Treating Relapses
Relapses that don’t severely impact a person’s ability to comfortably perform daily activities may self-correct without medical intervention. Mild sensory changes or periods of tiredness may resolve on their own.
“I determine whether to give steroids for a relapse based on how severe the relapses are and after a careful discussion with my patient,” said Dr. Nicholas. “If I see an individual who is having a small area of new numbness consistent with a new relapse, but it is not bothersome, we do not have to treat that individual with steroids. However, if somebody comes into my office and they can’t walk because of their relapse, I would strongly recommend steroid treatment and potentially plasmapheresis, if there is no or minimal benefit with steroids. This type of relapse is severe, and the goal would be to speed up recovery quickly,”.
Pharmaceutical Options
A short course of corticosteroids, such as Solu-Medrol (Methylprednisolone), Dexamethasone, or Prednisone, can speed up recovery from a relapse. “The most classic treatment would be [intravenous] steroids like Methylprednisolone for between three to five days,” advised Dr. Nicholas.
If a person doesn’t tolerate steroids well or doesn’t like the side effects, another injectable option is Acthar gel — purified adrenocorticotropic hormone. Acthar gel is extended-release and provides therapeutic benefits after it’s injected.
“Steroids have always helped me in the past whenever I had a flare-up,” shared a MyMSTeam member. “When I knew I was going to be on steroids, I would change my diet for three months following treatment, so as not to put on the extra weight.”
Recovering After a Flare-Up
Recovery from a relapse usually happens in the first two to three months after the flare. However, in some cases, healing may continue for up to 12 months.
Sometimes, a person’s relapse may be so severe as to warrant hospitalization and post-discharge rehabilitation. Depending on how an exacerbation affects a person, various health care professionals may be involved in recovery, including physical therapists, occupational therapists, and speech therapists.
Mental health is also important in recovering from a flare. “Make sure that mental health and emotional health is addressed,” Dr. Nicholas emphasized. “If somebody feels overly stressed, that can be really bad for the immune system and can be very harmful. In addition, stress can lead to an increase in chronic symptoms.”
Whether or not your flares are significant enough to warrant a trip to the doctor, you should report them to your health care provider. Relapses are a sign that your MS could be becoming more active. Only a qualified medical professional can tell for sure.
How do you manage your MS relapses? Have you ever had a pseudo-relapse? Share your experiences in the comments below or on MyMSTeam. There’s a network of support and a wealth of information waiting for you.
References
- Managing Relapses — National Multiple Sclerosis Society
- Managing relapses — Multiple Sclerosis Trust
- Rehabilitation — National Multiple Sclerosis Society
- MS Relapse Toolkit — Multiple Sclerosis Association of America
- Understanding and Treating MS Relapses — Multiple Sclerosis Association of America
- Primary progressive MS (PPMS) — National Multiple Sclerosis Society
- Secondary progressive MS (SPMS) — National Multiple Sclerosis Society
- Relapsing-remitting MS (RRMS) — National Multiple Sclerosis Society
- No evidence of disease activity (NEDA) — Multiple Sclerosis Trust
Exercise and multiple sclerosis – Mayo Clinic
I’ve been diagnosed with multiple sclerosis (MS). Is it okay to exercise?
Answer From Iris Marin Collazo, M.D.
Yes, people with MS can exercise. But, it’s best to take an individual approach, as levels of ability can vary. Common symptoms of MS, such as fatigue, weakness and poor coordination, may make the prospect of exercise daunting. But some studies show that the benefits of exercise far outweigh the challenges if you have MS — as long as you remember not to overdo it and that moderation is essential.
If you have MS, check with your doctor before starting a routine. People with MS can benefit from at least 30 minutes of physical activity at least three days a week. For someone with MS, exercise that’s too aggressive can bring on severe fatigue and injury and exacerbate symptoms. Though regular aerobic exercise can increase strength and balance, improve bowel and bladder control, and decrease spasticity related to MS, it can backfire if you don’t take a gentler approach.
You may experience numbness, tingling or blurred vision when you start to exercise. This is due to a rise in core body temperature resulting from exertion. Typically, symptoms will ease as your body cools down. You can manage your body temperature while you exercise with a cooling garment or device.
A physical therapist or fitness instructor familiar with MS can help create a routine that fits your capabilities and addresses issues such as body temperature, poor balance, fatigue and spasticity. He or she can also assist in monitoring your pulse and breathing rate to help you pace yourself and avoid overexertion. Pool exercise, such as water aerobics, also may help with balance and, therefore, reduce your risk of falls.
Anyone with MS can modify an exercise routine to meet his or her needs. Just remember to work within your range of ability and not to overdo it.
With
Iris Marin Collazo, M.D.
- Demyelinating disease: What can you do about it?
- Intermittent fasting
May 01, 2020
Show references
- Exercise as part of everyday life. National Multiple Sclerosis Society. http://www.nationalmssociety.org/Living-Well-With-MS/Health-Wellness/Exercise. Accessed April 17, 2017.
- Latimer-Cheung AE, et al. Effects of exercise training on fitness, mobility, fatigue, and health-related quality of life among adults with multiple sclerosis: A systematic review to inform guideline development. Archives of Physical Medicine and Rehabilitation. 2013;94:1800w.
- Brown C, et al. Barriers and facilitators related to participation in aqua fitness programs for people with multiple sclerosis. International Journal of MS Care. 2012;14:132.
- Motl RW, et al. Is physical exercise a multiple sclerosis disease modifying treatment? Expert Review of Neurotherapeutics. 2016;16:951.
- Heat and temperature sensitivity. National Multiple Sclerosis Society. http://www.nationalmssociety.org/Living-Well-With-MS/Health-Wellness/Heat-Temperature-Sensitivity. Accessed April 19, 2017.
See more Expert Answers
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Selma Blair Recalls Early MS Flare Symptoms in Instagram Photo
Stefanie KeenanGetty Images
- Selma Blair shared an Instagram photo recalling the symptoms she experienced during an early MS flare.
- Blair explains that she “didn’t know what was happening,” and that her “leg was dead.”
- Flares often make existing MS symptoms worse, leading to mobility issues, overwhelming fatigue, and even difficulty speaking.
If there’s one thing that stands out about Selma Blair’s multiple sclerosis (MS) journey, it’s her ability to be brutally honest about everything she’s gone through before, during, and after her diagnosis. On Thursday, she revealed another layer to her MS story in an Instagram post, where she recalled experiencing MS symptoms before she had been diagnosed.
She captioned the post: “A beautiful summer night in Miami. My flare was already hitting. I didn’t know what was happening. But I sat outside and had a gorgeous dinner with my dear friend. All we have is right now. This. Is the past. But I remember knowing to just feel the warmth in the breeze. The gift of this trip. Under the table my leg was dead. I couldn’t stay awake and my right hand couldn’t find my mouth. But I was happy.”
Blair, 46, was diagnosed with MS in August 2018, but admits that she experienced symptoms long before then. In a recent interview with Good Morning America, she explained that she saw several doctors before receiving an accurate diagnosis. “I had tears,” Blair said during the interview. “They weren’t tears of panic, they were tears of knowing that I now had to give in to a body that had loss of control and there was some relief in that.”
What is an MS flare, exactly?
Multiple sclerosis is a chronic inflammatory disease of the central nervous system (aka, your brain and spinal cord). An MS flare-up (also known as an exacerbation, relapse, or attack) happens when new symptoms appear or old symptoms get more difficult to manage, according to the National Multiple Sclerosis Society. Certain symptoms—such as fatigue, difficulty walking, vision problems, pain, and numbness or tingling—can impair a person’s ability to move or function properly.
In Blair’s case, flare-ups have hindered her ability to walk (she uses a cane and, more recently, a walking bike), move her hands, speak properly due to spasmodic dysphonia, and stay awake because of overwhelming fatigue.
During a flare-up, inflammation disturbs a person’s central nervous system by damaging myelin, or fatty substances that surround your nerve fibers. This causes communication problems among your nerve impulses, leading to disabling symptoms. An MS flare can last a few days, weeks, or even months. People also experience these exacerbations differently, and symptoms can vary greatly from person to person.
For severe MS flares, such as those that interfere with mobility, doctors will often prescribe a three to five day course of high-dose corticosteroids to tamp down inflammation quickly, according to the National Multiple Sclerosis Society.
Blair’s course of treatment is unknown, but she’s made it clear that she only plans to keep moving forward. Blair ended her post with a touching testament to the present: “My son is asleep next to me. I hear his breathing. That of a tender soul, a young boy who will wake full of energy. I am going to curl up next to him. Cause that is what this wonderful life can bring. The now. The now I love.”
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90,000 MS Vspyshkin died right in the metro. AUDIO
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The oldest Russian DJ had a heart attack
Vladimir Turkov, known as MS Vspyshkin, became ill on the escalator in the St. Petersburg metro. The 76-year-old DJ died without waiting for an ambulance. The guards who arrived at the scene discovered that the phone had been stolen from the already dead Turkov.
The pensioner Vladimir Turkov, popular among fans of electronic music, known as MS Vspyshkin, died at 14.30 in the metro of St. Petersburg.
“Citizen Turkov died this afternoon at the Ulitsa Dybenko metro station,” the press service of the city metro reported. The 76-year-old DJ became ill while descending the escalator.
According to Rosbalt, the musician’s son, Julian, who arrived at the scene, said that he tried to call his father during the day, but the phone was out of reach. Later it turned out that among the personal belongings of MS Vspyshkin there was no mobile. Perhaps he was pulled out on the escalator when the musician felt bad, or already downstairs at the metro station.As a result, Turkov Jr. was given only a bag with documents and his father’s hat.
The musician’s body lay by the escalator for more than three hours. Doctors who witnessed the fact of death wrapped the DJ in black plastic. Now the musician’s body will be sent for examination. According to a spokesman for the Investigative Committee, experts need to establish the causes of death. If they do not have a criminal background, the police will contact the relatives of MS Vspyshkin.
The funeral of Vladimir Turkov in accordance with his last will will be held at the Smolensk cemetery in St. Petersburg, RIA Novosti reports.
MC Vspyshkin – Russian DJ, musician, radio host, one of the founders and member of the musical group “MC Vspyshkin & Nikiforovna” was born on October 31, 1936.
In the 1990s, MC Vspyshkin took part in several large raves in St. Petersburg (“Sausage Shop”). Since the beginning of the 2000s, together with DJ Riga, he hosted the “TSEKH” program on the “Record” radio. I read on the same radio “Bedtime Stories from MC Vspyshkin”, which are also released in the form of audiobooks. In 2004 the album of the group “MC Vspyshkin & Nikiforovna” – “Sex” was released.MS Vspyshkin was also a member of the Petersburg Avant-garde project.
We add that the second member of the group – Dima Chekov “Nikiforovna” – in August 2011 crashed on a motorcycle in the Leningrad region.
MS Vspyshkin and Nikiforovna – I’m rushing
MS Vspyshkin: Dima “Nikiforovna” who died in the accident was a real star (photo)
SAINT PETERSBURG, August 23. Petersburg musician Dmitry Chekov “Nikiforovna”, who died in an accident in the Leningrad region, was a real star.Confirming the death of a partner, Vladimir Turkov (MS Vspyshkin) told a Rosbalt correspondent about this.
According to him, Dima was a master of improvisations and creative discoveries.
“I remember how we came to Malakhov in Moscow to star in his program” Big wash. “When we went out to the audience in the studio from the guest room, I suddenly felt that my legs suddenly gave way. It turned out that it was Mitya who unexpectedly jumped on riding me, I fell on all fours, and so he rode me into the studio.Malakhov almost fell off his chair, the audience laughed and applauded for a long time, “the musician recalls.
He also said that he was very worried about the death of his creative partner, which he learned on the night from Sunday to Monday from the project director Vladimir Krugovenkov.
“I’m shocked … How could this happen! How his mother will survive such grief! “- he said.
Recall that in the Luga district of the Leningrad region, 27-year-old musician Dmitry Chekov, better known under the pseudonym Dima Nikiforovna, died in an accident.The musical legend of the 2000s fell victim to an accident while returning with a friend on a motorcycle from a summer cottage.
According to the police, the accident was due to poor road surface. The driver survived, and Dima died on the spot from his injuries. The Luga police department said that the blame for the crash lies entirely with the driver.
The epotage project “MC Vspyshkin and Nikiforovna” united two bright personalities. Vspyshkin himself with a shaggy beard performs in youth pants with many pockets.Nikiforovna is a handsome young man named Dima, who pulls the choruses in an old woman’s voice with a characteristic pouting voice.
The Nikiforovna group itself was founded in 2002. It consisted of three members: Dmitry “Babka” Chekov (vocals), Fedor “Igolkin” Kunitsyn (arrangement), Anton “Scanner” Obraztsov (sound production). The group was rapidly gaining popularity, and in 2003 its hit with the words “Bumps fell in the forest, we go for sausage” blew up the charts of “Radio Record”, staying in first place for eight weeks, and became the anthem of the electronic music festival “Sausage Workshop 3 “.Soon, together with MC Vspyshkin, the Nikiforovna group recorded the legendary album “SEX”, which included such hits as “Sex”, “Discoteka”, “Good”, “Insomnia”, “Me Pret” and others.
Read more on Rosbalt in the near future.
90,000 Vspyshkin died of mental trauma
Nevertheless, he shocked those around him with his appearance. The DJ dressed in a youth style, could easily appear in front of the cameras in a thong, and also loved to visit a nude beach.Once, as a blockade, Vladimir came to receive the keys to a new apartment in Smolny, he was wearing a leather jacket with many rivets and iron “bells and whistles.” “You will scratch Valentina Matvienko,” the guards shouted and did not let grandfather inside. Only after he agreed to remain in one T-shirt, the security parted.
The youth especially loved the showman. Teenage girls often approached him for autographs, affectionately called him “grandfather” and said “thank you” for the positive that he brings into their lives.No one knew that in recent years, Vladimir Turkov experienced a real tragedy, because of which he had serious heart problems.
According to friends, Vspyshkin quarreled with the radio station “Record” two years ago, of which he was a DJ. The reason for the conflict: money. The producers organized VIP parties, tickets to which were mega-expensive, and Vspyshkin and his partner Dmitry Chekov (Nikiforovna) were paid $ 100 per performance. Turkov considered it injustice, and, moreover, he did not even ask for himself.
– I will live on retirement, and Dima has a big family that needs to be fed, – the DJ explained to the producers.
To which the organizers of the concerts replied that they would not raise the fee, the “grandfather” did not sign a contract with them and therefore could be free. Soon a doppelganger appeared on the scene, dressed “under Vysyshkin”, with the same beard. The new artist grimaced to the soundtrack and deceived the viewer, calling himself a false name. The real Vspyshkin was thrown out into the street.
– Once Volodya decided to expose the fraudsters, because he was a very honest person, and worried that the public was being cheated like that.Vspyshkin even went to court, – the artist and poet Irina Dudina, a friend of the DJ, told MK, – but then he gave up this venture. He explained that he did not want to waste his strength and nerves on squabbles.
But in his heart Vspyshkin was tormented by his own lack of demand. Another blow for him was the death of his friend and partner Dima Chekov, who was in a car accident. The old man did not go to Dima’s funeral, because there was a fake Vspyshkin, and the producers hinted: do not come, you will be superfluous there! After such an event, Vladimir for the first time had a heartache, he complained to his family about poor health and lay there for several days.
Vspyshkin did not smoke, did not drink and went in for sports. Before the situation with the “Record”, his health was excellent. Perhaps, if not for this scandal, the St. Petersburg eccentric lived for many more years. But it so happened that the “grandfather” fell into the metro, at the Dybenko station and never got up.
He was sincere, open and kind, recalls Irina Dudina. – Many people, becoming stars, spoil. And Vspyshkin was not like that. He did not refuse anyone anything, he gave autographs to everyone, communicated. There was always a crowd around him.And he was just amazing as a friend. When problems began in my family, Volodya supported me with advice, did not let me lose heart. He called me Muse, always went to my poetry evenings and exhibitions. He, as a youth, was interested in everything. We spent some wonderful vacations together. I with children, and Vspyshkin with his wife and grandchildren went to the Shelon River, to a real village house. We mowed the grass, swam in the river and played volleyball on the site that Volodya built himself.
According to friends, Vspyshkin was not rich.And he did not strive to take advantage of fame in order to receive material benefits. He often said that he wanted to live “like the whole people.” That is why he bought his breathtaking outfits for the occasion, at sales. The “people”, who loved their grandfather, nevertheless did not disdain and stole a mobile phone from his pocket when the DJ became ill on the subway.
… The musician will be buried at the Smolensk cemetery. According to the wife of the late Nadezhda Turkova, this was his will. The date of the funeral has not yet been determined.
Natalya Chernykh
Fragment from the last interview of Vladimir Turkov
DJ Vspyshkin: “When you are loved, this is happiness!”
– Why did you suddenly become a DJ?
– And this was already a retirement case.Perestroika, lack of money. I went to a village in the Pskov region – I have a house there. In the summer he lived in it. And in the village there was no light (the local hanygs cut all the wires), and as a result I grew like a devil, since I can only use an electric razor, and from a safe one I have irritation on my skin. Came to St. Petersburg with a beard to the waist. My wife says to me: “Go to Lenfilm, there the casting was announced to the crowd.” As a result, he played a lot of all sorts of roles. But I didn’t aspire to be a famous artist. I was so pleased with everything.And then the foreman from Lenfilm said that there was a casting of actors to advertise a disco. They took me. Then I got on the radio – they had the Flash program, that’s how they called me Flash. Began to lead discos.
– Did you look just as exotic during the Soviet era?
– No, what are you! I was inconspicuous. I even liked it. To be honest, I never aspired to fame. People like what I do, which means I feel good too. For example, in the Soviet Union, bodybuilding was prohibited.So is the guitar. Like, propaganda from the West. But since people had to, then I don’t care about any prohibitions. We called bodybuilding athletic gymnastics – and away we go! More than two hundred people were swinging … And in total 600 people were engaged in sports! I was constantly dragged to the district committee, worked out: “Stop engaging in social activities.” They did not understand that I was doing this from the heart, and not for the sake of self-interest. And after each such brainwashing, I ran to the post office and sent a telegram to Brezhnev: “Dear Leonid Ilyich, please accept me for a conversation on a very important public issue.”Sent 54 registered letters with notification! But I knew that they were not even opened, but sent directly to Smolny. There, of course, they were angry. They set OBKHSS on me. And once my friend (she was in love with a policeman, he blabbed everything to her at night) warned that a set-up was being prepared. Therefore, when I found a suitcase full of anti-Soviet literature left under the door, I was not surprised. I took this suitcase and went to Moscow to surrender to the KGB.
– Why ?!
– I decided to be ahead of the curve.I did not believe in the Leningrad KGB officers, so I went to the capital.
– You could have easily been put into a psychiatric hospital!
– Correct question. They came to my home, asked the neighbors: “Is he normal at all?” Later I was summoned to the OBKHSS and the KGB more than once, I came there all hung with bagels. I was preparing myself crackers in case of landing …
– Are you happy in your family life?
– I’m different at home. Pets do not abuse flashkins. In family life, anything can happen.As soon as a storm is brewing, I immediately remember how Nadia ran down the stairs to me in a fluttering coat … 35 years together. Recently we were with her in Sochi, I went to the beach in a thong, people fell.
– Your photograph, in which you are completely naked, was presented at a photo exhibition in the Russian Museum. What is this story?
– Everything happened by accident. There was some regular casting – not just porn, but artistic photography. So I undressed. Once I went to the Russian Museum, the caretakers looked at me for a long, long time, then asked: “It was not you who were hanging here?” The girls ran and took pictures.
– Did you carry some kind of image?
– I’m just standing naked – in socks and slippers. I am not ashamed of either my own or other people’s nudity. Sometimes, next to me, a hundred naked girls danced! On the Internet, fans created my page, so there I got 17 thousand friends in a month. They do not give a pass. At first I signed autographs with a simple squiggle, was ashamed to write “with love”, I was afraid that the guys of the girls might misunderstand me. But then he became liberated. Now I say this: “Where Vspyshkin falls in love, Othello, Casanova and their husbands are resting.”
– How does your wife feel about your popularity?
– Fine! Once we are walking down the street together, some 5-year-old boy shouts to me: “Hello, dude!” Nadia was offended. And I told her: “You don’t understand, this is a reward!” When you are loved – this is a colossal happiness!
Irina Molchanova
The legendary man has died Vladimir Turkov (MS Vspyshkin)
Today, at the age of 76, Vladimir Turkov (MS Vspyshkin) has died.
MC Vspyshkin is a legendary man, a member of the group “MC Vspyshkin and Nikiforovna”, whose hits are “Shishki”, “I’m rushing”, “Discoteka”, “Zenith, forward!” the whole country knew and loved.
MC Vspyshkin performed at the festivals “Sausage Shop”, “Flash”, toured a lot.
In August 2011, just 3 months ago, the second member of the MC Vspyshkin and Nikiforovna group, Dima Chekov (Nikiforovna), was tragically killed. These two amazing people will forever remain in our hearts.
Bright memory.
www.radiorecord.ru
Next …
MC Vspyshkin, real name Vladimir Alexandrovich Turkov (October 31, 1936 – November 14, 2011, St. Petersburg) – Russian DJ, electronic musician, radio host, one of the founders and member of the musical group “MC Vspyshkin & Nikiforovna”.
In the 90s MC Vspyshkin took part in several large raves in St. Petersburg (“Sausage Shop”). Since the beginning of the 2000s, together with DJ Riga, he hosted the “TSEKH” program on the “Record” radio.
Later on the same radio I read Bedtime Stories from MC Vysyshkin, which were also released in the form of audiobooks. In 2004 the album of the group “MC Vspyshkin & Nikiforovna” – “Sex” was released. In 2005 MC Vspyshkin took part in the recording of the track “Davaj Davaj” by the Danish Eurodance producer DJ Aligator. It was released as a CD single and was also featured on the DJ Aligator Project’s “Music Is My Language” album.
Known in St. Petersburg as a recognizable and benevolent freak.There are many photos of MC Vspyshkin with fans on the Internet.
A completely nude photograph of MC Vspyshkin was presented in 2004 at the exhibition of photographer Ali Esipovich in the Marble Palace of the Russian Museum and later sold at an auction in London for $ 5000. The musician used the proceeds to record a new album “Flash with donuts”.
On November 14, 2011, he died of a heart attack in St. Petersburg at the Ulitsa Dybenko metro station
MS Vspyshkin died at the Dybenko metro station
Popular DJ and showman Vladimir Turkov, better known as MC Vspyshkin, died on Monday in the St. Petersburg metro.
“At the Dybenko metro station, a 31- or 36-year-old man, VA Turkov, has died,” Yulia Shavel, press secretary of the St. Petersburg metro, told dp.ru. “The man felt bad. He died before the doctors arrived,” said Yulia Shavel.
The creator of the mole from the famous cartoon dies
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The creator of the mole from the famous cartoon dies
Radio Record confirmed that MS Vspyshkin really died at the Ulitsa Dybenko metro station.An employee of the radio station said that, most likely, the reason was related to the health of Vladimir Turkov.
Vladimir Turkov was born on October 31, 1936. There is a legend that MS Vspyshkin became the first DJ not only in Russia, but also in the world. Vspyshkin’s official website describes his biography in the “Legend” section.
In the 1970s, Vladimir Turkov was the administrator of the Nomads group. In the 90s MC Vspyshkin became a regular participant and brand of major rave events in St. Petersburg, such as “Sausage Workshop”.Since the early 2000s, Vladimir Turkov worked as a presenter at the radio “Record”.
MS Vspyshkin has released several albums. He could often be found in the St. Petersburg metro.
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Exhibition in memory of MC Vspyshkin opened in St. Petersburg
Almost 40 days have passed since the death of Vladimir Turkov – MC Vspyshkin.He was one of the most extraordinary cultural figures of St. Petersburg and a symbol of youth dance culture. In memory of the musician, an exhibition was opened in the art gallery on Kazanskaya Street.
There are not many professional photographs of Vladimir Turkov, and it seems strange. You still have to look for such colorful characters. Here MS Vspyshkin in orange tights is in the blockade column, Turkov survived the war in Leningrad. Walks in a superman suit. Here he is on rollers with a beard disheveled in the wind.Dressed as Santa Claus in the Navy. And topless during a musical pantomime.
This physical form at the age of 70 is a merit of the love of bodybuilding. He became interested in dumbbells in his youth, when he and his friends organized a semi-legal rocking chair in the yard.
Nadezhda Turkova, wife of Vladimir Turkov: “He evicted the people, somehow got out there, the people lived in apartments, when the basements were vacated, he began to set up a gym there”.
You can’t recognize him on old photographs.In a hat and jacket, Vladimir Turkov looks more like a Hollywood star. He also worked as an artist. In parallel, however, he was fond of music. He joked that he mixed records on gramophones.
Irina Dudina, poet: “This is the costume of the members of the vocal and instrumental ensemble of the Nomads group, which Vyshkin created at the end of the 50s. This was one of the first groups. When young guys played guitars and sang songs of their own composition. ”
MS Vspyshkin he became at the end of 90.The texture was noticed by the producers from the radio. In Turkov’s life, a “Sausage Shop” appeared, and people’s love began.
Dmitry Shagin, artist: “I met him almost every day, going to Marat’s studio. He went to meet, always joyful, at any time of the year. Such in a vest, with thorns, such a joyful one. He was a sign of our city, as a symbol of our city ”.
His friend, director Konstantin Seliverstov edited a documentary about Vspyshkin’s life. He says that with such a character, a script is not required.
Based on amateur footage. Most Turks wear the image of the famous raver. And only this unique video shows the unusual Vspyshkin. On them, he congratulates his 90-year-old mother on her birthday.
Correspondent: Ekaterina Linnikova
Operator: Sergey Smirnov
Lyrics of the song Ms Vspyshkin and Nikiforovna
Original lyrics and lyrics of the song
Best :
01.MS Vspyshkin and Nikiforovna – xDD (2:13)
02. MS Vspyshkin and Nikiforovna – Zenit-Champion (2:37)
03. MS Vspyshkin and Nikiforovna – Bros (2:55)
04. MS Vspyshkin and Nikiforovna – Dialogues About animals. (3:15)
05. MS Vspyshkin and Nikiforovna – Disco (3:18)
06. MS Vspyshkin and Nikiforovna – Zhest [MyDJ] (3:29)
07. MS Vspyshkin and Nikiforovna – Grandfather Marazm and Dumburochka (4 : 56)
08. MS Vspyshkin and Nikiforovna – Good (Pampariruram) (3:34)
09. MS Vspyshkin and Nikiforovna – Come on (feat.DJ Alligator) (5:23)
10. MC Vspyshkin and Nikiforovna – Le Shaurma (4:10)
11. MC Vspyshkin and Nikiforovna – I wander around (4:14)
12. MC Vspyshkin and Nikiforovna – New Year (I’m rushing ) (5:07)
13. MS Vspyshkin and Nikiforovna – Sausage shop 3 (cones) (4:29)
14. MS Vspyshkin and Nikiforovna – Good (Club Mix) (4:35)
15. MS Vspyshkin and Nikiforovna – La shawarma, for lovers of French chanson (4:42)
16. MS Vspyshkin and Nikiforovna – On autopathy (4:42)
17. MS Vspyshkin and Nikiforovna – Insomnia (5:22)
18.MS Vspyshkin and Nikiforovna – KPP (4:56)
19. MS Vspyshkin and Nikiforovna – New Year (4:59)
20. MS Vspyshkin and Nikiforovna – Sex (4:23)
Translation into Russian or English of the lyrics –
Best performer Ms Vspyshkin and Nikiforovna :
01. MS Vspyshkin and Nikiforovna – CDM (2:13)
02. MS Vspyshkin and Nikiforovna – Zenit-Champion (2:37)
03. MS Vspyshkin and Nikiforovna – Bros (2:55)
04. MS Vspyshkin and Nikiforovna – Dialogues about animals.(3:15)
05. MS Vspyshkin and Nikiforovna – Disco (3:18)
06. MS Vspyshkin and Nikiforovna – Tin [MyDJ] (3:29)
07. MS Vspyshkin and Nikiforovna – Santa and Pridurochka Insanity (4 : 56)
08. MS Vspyshkin and Nikiforovna – Good (Pampariruram) (3:34)
09. MS Vspyshkin and Nikiforovna – Come on let (feat DJ Alligator.) (5:23)
10. MS Vspyshkin and Nikiforovna – Le Shawarma (4:10)
11. MS Vspyshkin and Nikiforovna – I go wander (4:14)
12. MS Vspyshkin and Nikiforovna – Christmas (I was rushing) (5:07)
13.MS Vspyshkin and Nikiforovna – Sausage shop 3 (bumps) (4:29)
14. MS Vspyshkin and Nikiforovna – Good (Club Mix) (4:35)
15. MS Vspyshkin and Nikiforovna – La shawarma, for lovers of French chanson (4:42)
16. MS Vspyshkin and Nikiforovna – at an auto (4:42)
17.