What are the possible side effects of NovoLog® Mix 70/30 insulin? Learn about the serious and common side effects of this medication used to control high blood sugar in people with diabetes.

What is NovoLog® Mix 70/30?

NovoLog® Mix 70/30 is a man-made insulin used to control high blood sugar in people with diabetes mellitus. It is a mixture of 70% insulin aspart (the active ingredient in NovoLog®) and 30% insulin aspart protamine suspension, which is a longer-acting insulin.

Is NovoLog® Mix 70/30 Safe for Children?

It is not known if NovoLog® Mix 70/30 is safe and effective in children. The safety and efficacy of this medication have not been established in the pediatric population.

Sharing Needles and Syringes

Do not share your NovoLog® Mix 70/30 FlexPen® with other people, even if the needle has been changed. Do not share needles or syringes with another person. You may give other people a serious infection, or get a serious infection from them.

When Should You Not Take NovoLog® Mix 70/30?

Do not take NovoLog® Mix 70/30 if you are having an episode of low blood sugar (hypoglycemia) or you have an allergy to NovoLog® Mix 70/30 or any of its ingredients.

Informing Your Healthcare Provider

Before taking NovoLog® Mix 70/30, tell your healthcare provider about all your medical conditions, including if you are pregnant, planning to become pregnant, or are breastfeeding. Also, inform your provider about any new prescription or over-the-counter medicines, including supplements, that you are taking.

Managing Low Blood Sugar

Before you start taking NovoLog® Mix 70/30, talk to your health care provider about low blood sugar and how to manage it. It is essential to understand the signs and symptoms of hypoglycemia and how to respond appropriately.

Proper Use of NovoLog® Mix 70/30

Read the Instructions for Use and take NovoLog® Mix 70/30 exactly as directed by your healthcare provider. If you have type 1 diabetes, inject the medication within 15 minutes before you eat a meal. If you have type 2 diabetes, you may inject up to 15 minutes before or after starting your meal. Do not mix NovoLog® Mix 70/30 with other insulin products or use it in an insulin pump.

Monitoring Blood Sugar Levels

Check your blood sugar levels regularly. Ask your health care provider what your blood sugar levels should be and when you should check them. Proper monitoring is crucial for managing your diabetes effectively.

Injection Site Rotation

Change (rotate) your injection sites within the area you choose with each injection to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Do not use the exact same spot for each injection.

Avoid Injection in Certain Areas

Do not inject where the skin has pits, is thickened, or has lumps. Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin.

Driving and Operating Heavy Machinery

Do not drive or operate heavy machinery until you know how NovoLog® Mix 70/30 affects you. The medication can cause drowsiness, dizziness, or other side effects that may impair your ability to safely operate vehicles or machinery.

Alcohol and Medications

Do not drink alcohol or use medicines that contain alcohol, as they can interact with NovoLog® Mix 70/30 and affect your blood sugar levels.

Serious Side Effects

Serious side effects of NovoLog® Mix 70/30 can lead to death, including low blood sugar (hypoglycemia). Signs and symptoms of hypoglycemia include dizziness, light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heart rate, anxiety, irritability, mood changes, and hunger.

Other Common Side Effects

Other common side effects of NovoLog® Mix 70/30 may include low potassium in your blood (hypokalemia), reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions), skin thickening or pits at the injection site (lipodystrophy), weight gain, and swelling of your hands and feet.

Seek Emergency Medical Help

Get emergency medical help if you experience trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.

In conclusion, it is important to understand the potential side effects of NovoLog® Mix 70/30 and to take the necessary precautions to ensure safe and effective use of this medication. Always consult with your healthcare provider for guidance on managing your diabetes and any related side effects.

NovoLog® Mix 70/30 Side Effects

• NovoLog^® Mix 70/30 is a man-made insulin used to control high blood sugar in people with diabetes mellitus.
• It is not known if NovoLog^® Mix 70/30 is safe and effective in children.

Do not share your NovoLog^® Mix 70/30 FlexPen^® with other people, even if the needle has been changed. Do not share needles or syringes with another person. You may give other people a serious infection, or get a serious infection from them.

• Do not take NovoLog^® Mix 70/30 if you are having an episode of low blood sugar (hypoglycemia) or you have an allergy to NovoLog^® Mix 70/30 or any of its ingredients.

Before taking NovoLog^® Mix 70/30, tell your healthcare provider about all your medical conditions including, if you are:

• pregnant, planning to become pregnant, or are breastfeeding.
• taking new prescription or over-the-counter medicines, including supplements.

Before you start taking NovoLog^® Mix 70/30, talk to your health care provider about low blood sugar and how to manage it.

• Read the Instructions for Use and take exactly as directed by your healthcare provider.
• NovoLog^® Mix 70/30 starts acting fast. If you have type 1 diabetes, inject within 15 minutes before you eat a meal. Do not inject NovoLog^® Mix 70/30 if you are not planning to eat within 15 minutes. If you have type 2 diabetes, you may inject up to 15 minutes before or after starting your meal.
• Do not mix NovoLog^® Mix 70/30 with other insulin products or use in an insulin pump.
• Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to.
• Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them.
• Do not reuse or share your needles or syringes with other people. You may give other people a serious infection, or get a serious infection from them.
• NovoLog^® Mix 70/30 is injected under the skin (subcutaneously) of your stomach area, buttocks, upper legs, or upper arms.
• Change (rotate) your injection sites within the area you choose with each injection to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
  • Do not use the exact same spot for each injection.
  • Do not inject where the skin has pits, is thickened, or has lumps.
  • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin.

• Do not drive or operate heavy machinery, until you know how NovoLog^® Mix 70/30 affects you.
• Do not drink alcohol or use medicines that contain alcohol. 

Serious side effects can lead to death, including:

Low blood sugar (hypoglycemia). Some signs and symptoms include:

• Dizziness, light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heart rate, anxiety, irritability, mood changes, and hunger.

Your insulin dose may need to change because of:

• weight gain or loss, increased stress, illness, or change in diet or level of physical activity.

Other common side effects may include:

• low potassium in your blood (hypokalemia), reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions), skin thickening or pits at the injection site (lipodystrophy), weight gain, and swelling of your hands and feet.

Get emergency medical help if you have:

• trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.

• NovoLog^® Mix 70/30 is a man-made insulin used to control high blood sugar in people with diabetes mellitus.
• It is not known if NovoLog^® Mix 70/30 is safe and effective in children.

Please click here for NovoLog^® Mix 70/30 Prescribing Information.

NovoLog^® Mix 70/30 is a prescription medication.

• NovoLog^® Mix 70/30 is a man-made insulin used to control high blood sugar in people with diabetes mellitus.
• It is not known if NovoLog^® Mix 70/30 is safe and effective in children.

Do not share your NovoLog^® Mix 70/30 FlexPen^® with other people, even if the needle has been changed. Do not share needles or syringes with another person. You may give other people a serious infection, or get a serious infection from them.

• Do not take NovoLog^® Mix 70/30 if you are having an episode of low blood sugar (hypoglycemia) or you have an allergy to NovoLog^® Mix 70/30 or any of its ingredients.

Before taking NovoLog^® Mix 70/30, tell your healthcare provider about all your medical conditions including, if you are:

• pregnant, planning to become pregnant, or are breastfeeding.
• taking new prescription or over-the-counter medicines, including supplements.

Before you start taking NovoLog^® Mix 70/30, talk to your health care provider about low blood sugar and how to manage it.

• Read the Instructions for Use and take exactly as directed by your healthcare provider.
• NovoLog^® Mix 70/30 starts acting fast. If you have type 1 diabetes, inject within 15 minutes before you eat a meal. Do not inject NovoLog^® Mix 70/30 if you are not planning to eat within 15 minutes. If you have type 2 diabetes, you may inject up to 15 minutes before or after starting your meal.
• Do not mix NovoLog^® Mix 70/30 with other insulin products or use in an insulin pump.
• Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to.
• Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them.
• Do not reuse or share your needles or syringes with other people. You may give other people a serious infection, or get a serious infection from them.
• NovoLog^® Mix 70/30 is injected under the skin (subcutaneously) of your stomach area, buttocks, upper legs, or upper arms.
• Change (rotate) your injection sites within the area you choose with each injection to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
  • Do not use the exact same spot for each injection.
  • Do not inject where the skin has pits, is thickened, or has lumps.
  • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin.

• Do not drive or operate heavy machinery, until you know how NovoLog^® Mix 70/30 affects you.
• Do not drink alcohol or use medicines that contain alcohol. 

Serious side effects can lead to death, including:

Low blood sugar (hypoglycemia). Some signs and symptoms include:

• Dizziness, light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heart rate, anxiety, irritability, mood changes, and hunger.

Your insulin dose may need to change because of:

• weight gain or loss, increased stress, illness, or change in diet or level of physical activity.

Other common side effects may include:

• low potassium in your blood (hypokalemia), reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions), skin thickening or pits at the injection site (lipodystrophy), weight gain, and swelling of your hands and feet.

Get emergency medical help if you have:

• trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.

• NovoLog^® Mix 70/30 is a man-made insulin used to control high blood sugar in people with diabetes mellitus.
• It is not known if NovoLog^® Mix 70/30 is safe and effective in children.

Please click here for NovoLog^® Mix 70/30 Prescribing Information.

NovoLog^® Mix 70/30 is a prescription medication.

Look up your cost and a savings offer at NovoLogMix7030Savings.com.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1‑800-FDA-1088.

If you need assistance with prescription costs, help may be available. Visit www.pparx.org or call 1‑888-4PPA-NOW.

Talk to your health care provider about your diabetes management plan, including diet and exercise.

html source

Side effects and how to manage them

NovoLog (insulin aspart) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it to manage blood sugar levels in adults and children with either type 1 or type 2 diabetes.

Novolog is typically used long term if you and your doctor agree it’s safe and working well for you.

Here are some fast facts about NovoLog:

• Active ingredient: insulin aspart, which is a biologic
• Drug class: fast-acting insulin
• Drug form: solution for subcutaneous injection, which comes in the following forms:
  • multi-dose vial, for use with insulin syringes or an insulin pump
  • prefilled multi-dose FlexPen
  • prefilled multi-dose cartridge, for use with a reusable insulin pen

As with other drugs, NovoLog can cause side effects. Read on to learn about potential common, mild, and serious side effects. For a general overview of NovoLog, including details about its uses, see this article.

NovoLog can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

These are just a few of the more common side effects reported by people who took NovoLog in clinical trials:

• lipodystrophy (skin thickening or pitting around the injection site)
• hypoglycemia (low blood sugar)*
• injection site reactions*
• weight gain*
• fluid retention (swelling)*

* For more information about this side effect, see “Side effect specifics” below.

Mild side effects can occur with NovoLog use. This list doesn’t include all possible mild side effects of the drug. For more information, you can refer to NovoLog’s prescribing information.

Mild side effects that have been reported with NovoLog include:

• nausea
• diarrhea
• headache
• pain in your chest or abdomen
• weak reflexes
• infection, such as a fungal infection in your nails or a urinary tract infection
• inflammation in your sinuses
• lipodystrophy (skin thickening or pitting around the injection site)
• fluid retention (swelling)*
• mild hypoglycemia (low blood sugar)*
• injection site reactions*
• weight gain*
• mild allergic reaction*

These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you develop a side effect while taking NovoLog and want to tell the FDA about it, visit MedWatch.

* For more information about this side effect, see “Side effect specifics” below.

NovoLog may cause serious side effects, but these aren’t common. If you have certain medical conditions, you may be at increased risk for serious side effects from NovoLog. To learn more, see the “Precautions” section below.

The list below may not include all possible serious side effects of the drug. For more information, you can refer to NovoLog’s prescribing information.

If you develop serious side effects while taking NovoLog, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Serious side effects that have been reported and their symptoms include:

• Hypokalemia (low blood potassium). Symptoms can include:
  • constipation
  • fatigue
  • irregular heartbeat
  • muscle cramps
  • weakness
• Severe hypoglycemia (low blood sugar). *
• Severe allergic reaction.*

* For more information about this side effect, see “Side effect specifics” below.

NovoLog may cause several side effects. Here are some frequently asked questions about the drug’s side effects and their answers.

What side effects should I expect when using the NovoLog FlexPen?

This article discusses the side effects of all forms of NovoLog, including the NovoLog FlexPen. This means that the expected side effects will be the same whether you use a NovoLog insulin pen or a vial of NovoLog together with insulin needles and syringes.

If you have questions about side effects from a specific form of NovoLog, talk with your doctor.

What are the side effects of using too much NovoLog?

Taking too much of a medication such as NovoLog can cause side effects, some of which may be serious. This is known as an overdose.

Using too much NovoLog may cause hypoglycemia (low blood sugar) or hypokalemia (low blood potassium levels). Rarely, low blood sugar can be severe or even life threatening.

To learn more, see the “Side effect specifics” section below. You can also talk with your doctor or pharmacist to learn more about these side effects.

To avoid taking too much NovoLog, make sure you give yourself your doses exactly as your healthcare professional tells you. If you’re confused or having trouble using NovoLog, contact your doctor or pharmacist. They can make sure you know how to give yourself NovoLog doses correctly.

How do side effects of NovoLog compare with NovoLog 70/30?

NovoLog and NovoLog 70/30 are very similar medications. They both contain insulin aspart as the active ingredient. However, NovoLog 70/30 contains two types of insulin aspart. One type works in your body for slightly longer than regular insulin aspart.

So, you will use NovoLog 70/30 in a slightly different way to NovoLog. However, these two medications can cause very similar side effects, including low blood sugar, low blood potassium levels, and injection site reactions.

To learn more about how NovoLog and NovoLog 70/30 compare, talk with your doctor or pharmacist.

Learn more about some of the side effects that NovoLog may cause. To find out how often side effects occurred in clinical trials, see the prescribing information for NovoLog.

Weight gain

Similarly to other types of insulin, Novolog can cause weight gain. It’s not known how common this side effect occurred in clinical trials of the drug, or how much weight was gained on average.

Weight gain may also be due to fluid retention (swelling), which is another side effect that Novolog may cause. To learn more, see “Fluid retention” below.

Certain medications may cause fluid retention and weight gain if you take them in combination with NovoLog. See the “Precautions” section below to learn more.

What you can do

If you’re concerned about weight gain while using NovoLog, talk with your doctor. Together, you and your doctor can develop ways to maintain a weight that’s healthy for you. Typically, people do not need to stop using NovoLog due to weight gain.

Hypoglycemia

Hypoglycemia (low blood sugar) is the most common side effect caused by all insulin drugs, including NovoLog.

NovoLog is used to manage blood sugar levels in adults and children with either type 1 or type 2 diabetes. Diabetes causes blood sugar levels to become too high. NovoLog works to lower blood sugar levels. However, these medications can cause blood sugar levels to drop too low, causing hypoglycemia.

Usually, hypoglycemia from NovoLog is mild. Symptoms of mild hypoglycemia can include:

• blurry vision
• dizziness
• headache
• hunger
• irritability
• sweating

However, NovoLog can also cause severe hypoglycemia in rare cases. Severe hypoglycemia can be life threatening and may require hospitalization if it isn’t treated right away. Your risk for severe hypoglycemia from NovoLog is higher if you skip meals. (You should give yourself your dose of NovoLog about 5 to 10 minutes before a meal).

Symptoms of severe hypoglycemia can include:

• confusion
• fainting
• seizures
• loss of consciousness or coma

What you can do

If your doctor prescribes NovoLog for you, you and your doctor should make a plan for how you’ll handle hypoglycemia if it happens. You should regularly check your blood sugar while using NovoLog according to your doctor’s instructions.

It’s possible to treat mild hypoglycemia by immediately eating or drinking glucose (simple sugar). You should try to take in at least 15 grams of sugar. Examples of good sources for simple sugar include:

• ½ cup fruit juice, such as orange or apple juice
• 3 to 4 glucose tablets
• 1 tablespoon of sugar or honey
• ½ cup of non-diet soda

Severe hypoglycemia needs immediate treatment. For treating severe hypoglycemia, your doctor may prescribe an emergency drug called glucagon. This is a medication given by injection or nasal spray if your blood sugar becomes severely low and you can’t take sugar by mouth. You’ll need someone else to give you this treatment, such as a friend, partner, or coworker who knows how to recognize and treat severely low blood sugar. Examples of glucagon medications include GlucaGen and Baqsimi.

If you have hypoglycemia symptoms that feel life threatening, immediately call 911 or seek emergency medical help. Do not attempt to drive yourself to the hospital if you are having severe hypoglycemia symptoms.

Fluid retention

Similarly to other types of insulin, NovoLog may cause fluid retention (swelling) as a side effect. This is one of the more common side effects caused by NovoLog.

Fluid retention happens when there’s a buildup of water in your body. Using insulin drugs such as NovoLog can lead to fluid retention because insulin causes your body to retain (hold on to) more salt than usual. Salt helps regulate the amount of water in your body. Having a higher level of salt in the body will likely cause you to have a higher level of water in the body, too.

Fluid retention caused by NovoLog typically affects your hands, feet, and lower legs.

What you can do

Talk with your doctor if you notice fluid retention while using NovoLog.

In some cases, this side effect goes away with time. This may be the case if your blood sugar levels were previously not managed. Starting treatment with an insulin drug such as NovoLog can cause fluid retention if the drug quickly lowers your blood sugar levels.

But if you have fluid retention that doesn’t go away or bothers you, your doctor may decide it’s best that you stop treatment with NovoLog. In this case, they can discuss other treatment options for your diabetes.

Injection site reactions

You may experience injection site reactions from using NovoLog. These were among the more common side effects reported in the drug’s clinical trials.

Injection site reactions are side effects which occur at the place where you inject your NovoLog doses. (NovoLog comes as a solution for subcutaneous injection).

Injection site reactions that may occur with NovoLog include:

• itchiness
• pain
• skin rash, discoloration, redness, or warmth
• swelling

What you can do

You can lower your risk for injection site reactions with NovoLog by rotating the place where you inject each dose. You can inject NovoLog doses under the skin of your thigh, abdomen, and upper arm.

Rotating the injection site can help prevent skin irritation, which may help avoid injection site reactions.

If an injection site reaction does occur while you’re using Novolog, keep in mind that most of these reactions go away on their own within hours or a few days. These reactions are typically mild.

But if you develop a reaction that bothers you or won’t go away, let your doctor know. They may want to see your reaction in person to determine if there could be another cause. They may also suggest switching to a different diabetes medication.

Allergic reaction

As with most drugs, NovoLog can cause an allergic reaction in some people. Mild, local reactions at the injection site (such as skin rash) were common in clinical trials. However, in rare cases, the drug can cause more serious allergic reactions, including anaphylaxis.

Symptoms can be mild or serious and can include:

• skin rash
• itching
• flushing
• swelling under your skin, typically in your lips, eyelids, feet, or hands
• swelling of your mouth, tongue, or throat, which can make it hard to breathe

What you can do

For mild symptoms of an allergic reaction, call your doctor right away. They may recommend ways to ease your symptoms and determine whether you should keep taking NovoLog. However, if your symptoms are serious and you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Be sure to talk with your doctor about your health history before you take NovoLog. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. These are considered drug-condition or drug-factor interactions. The conditions and factors to consider include:

Heart failure. Certain diabetes medications called thiazolidinediones can worsen heart failure symptoms if they’re used in combination with NovoLog. Examples of thiazolidinediones include Actos (pioglitazone) and Avandia (rosiglitazone). Be sure to tell your doctor about all medications you take before you start treatment with NovoLog. If you use NovoLog in combination with a thiazolidinedione, your doctor may have you stop taking one drug or another if your heart failure symptoms worsen during treatment.

Kidney or liver problems. People with kidney or liver problems may be at higher risk for hypoglycemia (low blood sugar) from using NovoLog. Examples of these problems include alcoholic liver disease and chronic kidney disease. It’s usually safe for people with these problems to use NovoLog. However, your doctor may want to closely monitor your blood sugar levels during treatment.

Hypokalemia (low blood potassium level). All insulins, including NovoLog, can cause hypokalemia (low blood potassium levels). Using NovoLog may worsen your condition if your potassium levels are already low. Your doctor will likely monitor your potassium levels while you use NovoLog.

Allergic reaction. If you’ve had an allergic reaction to NovoLog or any of its ingredients, your doctor will likely not prescribe NovoLog. Ask your doctor what other medications may be better options for you.

Alcohol with NovoLog

Talk with your doctor about whether it’s safe for you to drink alcohol while using NovoLog.

Alcohol and NovoLog can lower blood sugar levels. If you combine the two, you may raise your risk for hypoglycemia, which can be severe.

Talk with your doctor about whether it’s safe for you to drink alcohol while using NovoLog. They can also suggest how much (if any) may be safe for you to drink during treatment.

Pregnancy and breastfeeding while taking NovoLog

The American Diabetes Association recommends insulin, including NovoLog, as the preferred treatment for managing blood sugar levels in pregnant people with diabetes.

Data from clinical trials have not shown harmful effects of NovoLog in pregnancy. However, high blood sugar levels are known to raise the risk for pregnancy complications.

It’s not known whether NovoLog passes into human breast milk, or if it could cause side effects in a breastfed child.

If you’re pregnant, planning to become pregnant, or breastfeeding, talk with your doctor about the safest treatment option for your condition. They can recommend alternative feeding options for your child.

It’s possible to have mild or severe side effects from using Novolog, although severe side effects aren’t common in clinical trials.

Insulins, such as NovoLog, can cause hypoglycemia (low blood sugar) which is usually mild but can be severe in rare cases. NovoLog, like other insulins, commonly causes weight gain and fluid retention (swelling) as well.

If you’d like to learn more about NovoLog, talk with your doctor or pharmacist. They can help answer any questions you have about side effects from taking the drug.

Besides talking with your doctor, you can do some research on your own. These articles might help:

• More information about NovoLog. For details about other aspects of NovoLog, refer to this article.
• Drug comparison. To learn how NovoLog compares with Humalog, read this article.
• A look at your condition. For details about diabetes, see our diabetes hub and this list of related articles.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Novolog side effects: common, severe, long-term

Generic name: insulin aspart

Physical examination Drugs.com. Last updated: November 12, 2020

Note: This document contains information about the side effects of insulin aspart. Some of the dosage forms listed on this page may not are branded as Novolog.

Summary

Common side effects of Novolog include: Hypoglycemia. See below for a complete list of side effects.

Consumer

Refers to kinsulin aspart: solution

the active substance contained in Novolog) may cause some unwanted effects.

Although not all of these side effects may occur, if they do occur, medical attention may be required.

Consult your physician immediately if any of the following side effects occur while taking insulin as a part: 0059

Less common injections

Rare

• bloating abdomen or swelling of the face, arms, hands, legs, or feet
• difficulty breathing or swallowing
• rapid weight gain
• redistribution or accumulation of body fat
• swelling of the face, throat, or tongue
• unusual weight gain or loss

Side effects not requiring immediate medical attention

Some side effects of insulin aspart may occur, which usually do not require medical attention help . These side effects may disappear during treatment as your body adjusts to the medication. In addition, your healthcare provider can tell you about ways to prevent or reduce some of these side effects.

pain relief cream to stay in bed longer

Talk to your doctor if any of the following side effects continue or bother you or if you have any questions about them:

More common

• Back pain
• body pain 90 059
• chills
• cough
• diarrhea
• stuffy ear
• fever
• loss of voice
• muscle pain
• sneezing
• sore throat
• stuffy or runny nose

For healthcare workers

Related to insulin aspart: solution for injection, solution for subcutaneous administration

Generic

Observed adverse reactions included hypoglycemia, allergic reactions, local injection site reactions, lipodystrophy, pruritic rash. ^{[ Link ]}

Hypersensitivity

Very rare (less than 0.01%): Anaphylaxis

Common (1% to 10%): allergic skin manifestations.

Frequency not reported : Allergic reactions ^{[ Link ]}

Side effects of hypersensitivity include both local and systemic reactions. Anaphylaxis has been reported. Local reactions are presented as erythema, local edema, itching at the injection site. Most minor reactions to insulin at the injection site resolve within a few days to a few weeks.

A generalized allergy to insulin may present with a rash all over the body, shortness of breath, wheezing, hypotension, tachycardia, or sweating. In clinical studies, allergic reactions were reported in 0.7% (10/1394) of patients treated with insulin aspart.

Clinical trials with Fiasp® reported generalized hypersensitivity reactions in 0.2% (comparative 0.1%). Anaphylactic reactions have not been reported. Allergic skin manifestations were reported in 1. 5% (compared to 1.4%) and included eczema, rash, itchy rash, urticaria, and dermatitis. ^{[ Ref ]}

Metabolic

Very common (10% or more): Hypoglycemia

Frequency not reported : Weight gain ^{[ Ref ]} 90 007

Weight gain has been reported with insulin therapy, attributed to anabolic insulin action and reduced glycosuria. ^{[ Ref ]}

Local

Localized cutaneous amyloidosis at the injection site has been reported with resulting hyperglycemia with repeated injections of insulin into the area; Hypoglycemia has been reported with sudden movement to an unaffected injection site.

Common (1% to 10%): injection site reactions (including rash, redness, inflammation, pain, itching and bruising)

Frequency not reported : Lipodystrophy (including lipohypertrophy, lipoatrophy)

900 02 Post-marketing reports : Localized cutaneous amyloidosis at injection site.

Cardiovascular

Insulin may cause sodium retention and edema, especially as metabolic control improves. ^[Link]

General (1% to 10%): chest pain

how long should your penis be

Unusual (0.1% to 1%): peripheral edema. ^{[ Link ]}

Dermatological

Prolonged use of insulin may cause lipodystrophy at the site of repeated injection. Lipodystrophy includes lipohypertrophy, thickening of adipose tissue, and lipoatrophy, thinning of adipose tissue. ^[link]

General (1% to 10%): skin disorders, eczema, dermatitis.

Unusual (0.1% to 1%): urticaria, rash.

Frequency not reported : Lipodystrophy, including lipohypertrophy and lipoatrophy. ^{[ Link ]}

immunological

Generic (1% to 10%): Onychomycosis

Frequency not reported : Anti-insulin antibody titers ^{[ Link ] 9 0223}

The clinical significance of these antibody titers is unknown. ^{[ Link ]}

Eyepiece

Unusual (0. 1% to 1%): refractive error, worsening diabetic retinopathy ^{[ Link ]}

walking reversible impairment of ophthalmic refraction and deterioration in the course of diabetes. retinopathy. However, long-term glycemic control reduces the risk of diabetic retinopathy. ^{[ Link ]}

Nervous system

Rapid improvement in glycemic control has been associated with transient, reversible acute morbidity. Peripheral neuropathy. However, long-term glycemic control reduces the risk. ^{[ Ref ]}

Very common (10% or more): Headache (up to 12%)

Common (1% to 10%): hyporeflexia, impaired sensation.

Rare (less than 0.1%): painful peripheral neuropathy. ^{[ Ref ]}

gastrointestinal

Common (1% to 10%): nausea, diarrhea, abdominal pain ^{[ Ref ]}

urogenital

9 0002 Common (1% to 10%): urinary tract infection. ^[Link]

Musculoskeletal system

General (1% to 10%): back pain. ^[Ref]

respiratory

Very common (10% or more): Nasopharyngitis (23%)

Common (1% to 10%): upper respiratory tract infection. ^{[ Link ]}

Recommendations

1. “Product information. Novolog (insulin aspart) Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.

2. “Product information. Fiasp (insulin aspart). Novo Nordisk Pharmaceuticals Inc, Princeton, New Jersey.

3. Cerner Multum, Inc. “Australian Product Information”. O 0

4. Cerner Multum, Inc. “Brief overview of product characteristics for the UK”. O 0

More information

Always check with your health care provider to make sure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You can report them to the FDA.

Novolog Injectable in English – Product

Novolog Injectable in English – Product – TabletWise.com

• Terms of use

• Overview
• Benefits
• Side effects
• Precautions
• Interactions
• Contraindications

Overview

Novolog Injectable is used for Diabetes mellitus and other conditions.

Novolog Injectable contains the following active ingredients: Insulin Aspart Recombinant. Available in injectable form.

Detailed information regarding the use, composition, dosage, side effects of Novolog Injectable / Novolog Injectable, as well as user reviews are provided below:

Novolog Injectable is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

• Diabetes

Learn more: side effects

Below is a list of possible side effects that may be caused by elements that are part of Novolog Injectable / Novolog Injectable. This list is not final. These side effects have been recorded previously, but are not always recorded when using the drug. Some of these side effects may be extremely rare, but have incredibly severe consequences. If you notice any side effects, contact your doctor immediately. Especially in the case of observing side effects for a long time.

• Hypoglycemia
• Lipodystrophy at the site of repeated insulin injections
• Weight gain
• Peripheral edema
• Headache
• Nausea

9010 6

If you experience side effects not listed above, contact your healthcare provider for advice. In addition, you can report side effects to your local Food and Drug Administration.

Precautions

Before starting this drug, tell your doctor about any medications you are taking, nutritional supplements (eg vitamins, natural supplements, etc.), allergies, existing medical conditions, and current health conditions (eg, pregnancy, upcoming surgery, etc.). The side effects of the drug may be more pronounced depending on the state of your body. Take this medicine as directed by your doctor, or follow the directions for use that come with your medicine. The dosage of the drug depends on your condition. Tell your doctor if there is no change or if your condition worsens. Important points to discuss with your healthcare provider are listed below.

• do not confuse this medicine with other insulins
• monitor your blood glucose regularly

If you take other drugs or supplements at the same time as this medicine, the effects of Novolog Injectable may change. Tell your healthcare provider about all medications, vitamins, and supplements you use. Your doctor will be able to make the right plan for taking the drug, which will avoid negative interactions. Novolog Injectable may interact with the following drugs and products:

• ACE inhibitors
• Alcohol
• Antipsychotics
• Beta-blockers
• Clonidine
• Corticosteroids
• Danazol
• Disopyramide
• Diuretics
• Guanethidine

Hypersensitivity to Novolog Injectable / Novolog Injectable is a contraindication. In addition, Novolog Injectable should not be used if you have the following conditions:

• hypoglycemia
• hypersensitivity

Composition and active ingredients

Novolog Injectable contains the following active ingredients (salts) 059

Please note that this medicine is manufactured with different intensity strength for each of the active ingredients mentioned above.

Packaging options and drug strengths

Novolog Injectable is available in the following packages and strengths

Available packages of Novolog Injectable: 1000 UNITS/10ML (100 UNITS/ML)

FAQ

• 9000 2 Is it safe to drive or operate heavy machinery when using this product?

  If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Novolog Injectable medicine then it may not be safe to drive a vehicle or operate heavy machinery. You should stop driving if taking this medicine makes you drowsy, dizzy, or hypotensive. Doctors recommend that you stop drinking alcohol with such drugs, because. alcohol greatly increases the side effects and drowsiness. Please check for these effects on your body when using Novolog Injectable. Be sure to consult your doctor for advice based on the characteristics of your body and general health.

• Is this drug (product) addictive or addictive?

  Most drugs are not habit-forming or addictive. In most cases, the state classifies drugs that can be addictive as controlled dispensing drugs. For example, schedule H or X in India and schedule II-V in the USA. Please check the information on the drug packaging to make sure that this drug is not in the controlled category. Also, do not self-medicate or accustom your body to medications without consulting your doctor.

• Can I stop using this product immediately or do I need to slowly stop using it?

  Some medications need to be stopped gradually due to a rebound effect. Be sure to consult your healthcare provider for advice based on your body, general health, and other medications you may be taking.

Cite this page

Page URL

HTML Link

Novolog Injectable

APA Style Citation – Product – TabletWise.com. (n.d.). Retrieved April 12, 2023, from https://www.tabletwise.com/us-ru/novolog-injectable

MLA Style Citation

• “Novolog Injectable in English – Product – TabletWise.com” Tabletwise.com . N.p., n.d. Web. 12 Apr. 2023.

Chicago Style Citation

• “Novolog Injectable in English – Product – TabletWise.com” Tabletwise. Accessed April 12, 2023. https://www.tabletwise.com/us-ru/novolog-injectable.

More information about Novolog Injectable

• Uses of
• Reviews

• What are the uses of Novolog Injectable?
• What are the side effects of Novolog Injectable?
• What other medicines does Novolog Injectable interact with?
• When should you not take Novolog Injectable?
• What precautions should you take while using Novolog Injectable?

Last update date

This page was updated on 9/27/2020.