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Miconazole Topical vs Nystatin Topical Comparison

Miconazole Topical vs Nystatin Topical Comparison – Drugs.com
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View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.

</p> <p> May also be prescribed off label for Balanoposthitis. </p> ”> Prescription and OTC Prescribed for Vaginal Yeast Infection, Cutaneous Candidiasis, Oral Thrush, Tinea Cruris, Tinea Pedis, Tinea Versicolor, Intertrigo, Tinea Corporis. May also be prescribed off label for Balanoposthitis. View more	</p> <p> nystatin topical may also be used for purposes not listed in this comparison guide. </p> ”> Prescription only Prescribed for Cutaneous Candidiasis, Vaginal Yeast Infection, Paronychia. nystatin topical may also be used for purposes not listed in this medication guide.	Related suggestions Vaginal Yeast Infection Fluconazole Diflucan Clotrimazole topical Gyne-Lotrimin Clotrimazole-3 Terconazole topical Cutaneous Candidiasis Clotrimazole topical Nystatin / triamcinolone topical Ketoconazole topical Nystop Terbinafine Lamisil Popular comparisons Miconazole topical vs fluconazole Miconazole topical vs Monistat 7 Miconazole topical vs Tioconazole 1 Day Miconazole topical vs tioconazole topical
More about Miconazole topical	More about Nystatin topical
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Lower-cost generic is available	Lower-cost generic is available
Ratings & Reviews
Miconazole topical has an average rating of 3. 0 out of 10 from a total of 4207 ratings on Drugs.com. 15% of reviewers reported a positive effect, while 71% reported a negative effect.	Nystatin topical has an average rating of 5.6 out of 10 from a total of 26 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 38% reported a negative effect.
View all 4207 reviews	View all 26 reviews
Drug Class
Topical antifungals Vaginal anti-infectives	Topical antifungals
Side Effects
See also: miconazole topical side effects in more detail.	See also: nystatin topical side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 14 gram(s) Dosage 2% Per Unit* $0.73 Cost* $10.21 View all miconazole topical prices	Quantity 15 gram(s) Dosage 100000 units/g Per Unit* $1.13 Cost* $16.96 View all nystatin topical prices
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Dosage Form(s) Available
Topical cream Topical liquid Topical powder Vaginal cream with applicator Vaginal kit Vaginal suppository	Topical cream Topical ointment Topical powder
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.
N/A	N/A
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Is not subject to the Controlled Substances Act.	Is not subject to the Controlled Substances Act.
Pregnancy Category
See the full pregnancy warnings document.	See the full pregnancy warnings document.
Drug Interactions
A total of 3 drugs are known to interact with miconazole topical: 3 major drug interactions (6 brand and generic names)	No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Alcohol/Food/Lifestyle Interactions
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
First Approval Date
January 08, 1974	September 08, 1964
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N/A	N/A
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Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug interactions Pricing and coupons	Side effects Pregnancy warnings Breastfeeding warnings Dosage information Pricing and coupons En Español
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Which drug to choose: nystatin or clotrimazole?

Nystatin or clotrimazole: which drug to choose for the treatment of fungal infections? Learn about the benefits and uses of each to help you make the right choice.

Fungal infections are one of the most common problems in the field of dermatology. Often people experience such unpleasant symptoms as itching, redness and peeling of the skin. Various drugs are widely used to treat fungal infections, some of which are nystatin and clotrimazole.

Nystatin is an antifungal drug that is effective against Candida. It is used to treat fungal infections of the skin, mucous membranes and internal organs. Nystatin is available in various forms: ointment, cream, mouthwash. It has a high degree of safety and is well tolerated by patients.

Clotrimazole is another antifungal drug that is widely used to treat fungal infections of the skin and mucous membranes. It is effective against most types of fungi, including Candida. Clotrimazole is available as a cream, ointment, or solution. It is well absorbed into the skin and has a quick healing effect.

The choice between nystatin and clotrimazole depends on the individual situation and the doctor’s advice. Nystatin is usually recommended for the treatment of Candida infections, especially in the oral area. Clotrimazole is usually recommended for the treatment of infections of the skin and mucous membranes caused by various types of fungi. In any case, before using any drug, you should consult your doctor.

Nystatin or clotrimazole: which drug should I choose?

When choosing between nystatin and clotrimazole, it is important to consider the characteristics of each drug and the nature of the disease. Nystatin and clotrimazole are antifungal drugs, but act differently on pathogenic fungi.

Nystatin is widely used in the treatment of candidiasis caused by Candida albicans. It inhibits the growth and reproduction of fungi, which helps to eliminate the symptoms of the disease, such as itching, burning, and discharge. Nystatin is usually applied as a topical treatment in the form of a cream, ointment, or mouthwash.

Clotrimazole is also effective against Candida albicans as well as other fungi such as Trichophyton and Epidermophyton. It penetrates into the cells of fungi and breaks their membrane, which leads to their death. Clotrimazole is available in various forms including cream, ointment, solution, suppositories, and tablets.

When choosing between nystatin and clotrimazole, it is important to consider the site of the lesion and the severity of the disease. For example, nystatin may be preferred for treating oral candidiasis, and clotrimazole for treating fungal infections of the skin or nails. In some cases, a doctor may recommend a combination treatment using both drugs.

It is important to remember that nystatin and clotrimazole are drugs and should only be used as directed by a physician. If you have any doubts or side effects, you should contact a specialist for advice and recommendations.

Nystatin versus clotrimazole

Nystatin and clotrimazole are two drugs that are widely used to treat fungal infections. They have different mechanisms of action and methods of application, which affects their effectiveness and choice depending on the specific situation.

Nystatin is an antifungal drug that works by inhibiting the growth and reproduction of fungi. It is mainly used to treat candidiasis, including thrush and fungal infections of the mouth. Nystatin is available in various forms, including ointment, capsules, and suspension. It has low toxicity and is well tolerated by most patients.

Clotrimazole is also an antifungal drug, but its mode of action is different from that of nystatin. It acts on fungal cells, damaging their membranes and preventing their reproduction. Clotrimazole is used to treat various fungal infections of the skin, nails and mucous membranes. It is available as a cream, ointment, solution, and tablets.

The effectiveness of nystatin and clotrimazole may vary depending on the type of fungal infection and its location. For example, nystatin may be more effective in treating oral candidiasis because it has antifungal activity at the contact surface. However, clotrimazole may be preferable for the treatment of fungal infections of the skin and nails, as it has a broader spectrum of action and can penetrate deeper into tissues.

In general, the choice between nystatin and clotrimazole should be based on the advice of the physician, the type and location of the fungal infection, and the individual patient. It is important to follow the recommendations for dosage and duration of treatment to achieve the best results and prevent relapses.

Differences in formulations

Nystatin and clotrimazole are two different drugs used to treat fungal infections of the skin and mucous membranes. They have a different composition, which determines their different mechanisms of action and range of applications.

Nystatin is an antifungal drug whose main active ingredient is nystatin. This antimicrobial drug prevents the reproduction of fungi, inhibiting their growth and development. Nystatin acts on the cell membranes of fungi, damaging their structure and preventing the normal functioning of fungal cells.

Clotrimazole, in turn, contains the active ingredient clotrimazole. This antifungal drug has a wide spectrum of action and is effective against various types of fungi. Clotrimazole acts by inhibiting the synthesis of ergosterol, which is an important component of fungal cell membranes. This leads to damage to the structure of fungal cells and their death.

Thus, nystatin and clotrimazole have different active components and mechanisms of action, which determines their different properties and effectiveness in the treatment of fungal infections. When choosing a drug, it is necessary to take into account the characteristics of the disease and the recommendations of the doctor.

Spectrum of action of nystatin and clotrimazole

Nystatin and clotrimazole are two antimycotic drugs that are often used to treat fungal infections. However, they have a different spectrum of action and can be effective in different cases.

Nystatin is a polyene antibiotic that is active against various types of fungi, including Candida albicans. It is highly effective against fungal infections of the skin, mucous membranes of the mouth, gastrointestinal tract and vagina. Nystatin works by destroying the cell membranes of fungi, which leads to their death.

Clotrimazole is an imidazole antimycotic that is also effective against various fungal species, including Candida albicans. However, it can also be used to treat infections caused by dermatophytes and yeasts. Clotrimazole inhibits the growth of fungi by blocking their ability to produce ergosterol, an important component of fungal cell membranes.

In general, nystatin and clotrimazole have a broad spectrum of activity against fungal infections. However, when choosing between them, it is important to take into account the specific disease and its localization. For example, nystatin is often used to treat infections of the oral mucosa, while clotrimazole may be more effective for fungal infections of the skin and nails.

Advantages of nystatin over clotrimazole

1. Wider spectrum of action. Nystatin is an antifungal drug that is effective against most types of fungal infections, including Candida spp. and other fungi that cause diseases of the skin and mucous membranes.

2. Less likely to develop resistance. Nystatin acts by penetrating the cell membranes of fungi and disrupting their structure. This reduces the likelihood of developing resistance to the drug, in contrast to clotrimazole, which can cause the development of resistant strains of fungi.

3. Fewer side effects. Nystatin is poorly absorbed into the systemic circulation and therefore has minimal systemic effects. This avoids many side effects associated with exposure to organs and body systems. Unlike nystatin, clotrimazole can cause skin irritation and dryness, burning and redness, which can be unpleasant for the patient.

4. Safe for use in pregnant and lactating women. Nystatin has no toxic properties and can be used to treat fungal infections in pregnant and lactating women without risk to the development of the fetus or child.

5. Availability and low cost. Nystatin is one of the most affordable and affordable antifungals on the market. This makes it the preferred choice for patients with limited financial means.

Advantages of clotrimazole over nystatin

Clotrimazole is a drug that has several advantages over nystatin in the treatment of fungal infections.

First, clotrimazole has a broad spectrum of activity, which makes it suitable for the treatment of various types of fungal infections, including candidal infections. Nystatin, in turn, has limited activity and is not always effective against all types of fungi.

Secondly, clotrimazole is highly effective and has a fast onset of action. It is able to quickly destroy fungi and eliminate the symptoms of infection. Nystatin, on the other hand, requires longer use to achieve the same effect.

In addition, clotrimazole is available in various forms such as creams, ointments and solutions, making it easy to apply to different areas of the body. Nystatin is most often available only in the form of a cream or ointment.

It is also worth noting that clotrimazole has fewer side effects than nystatin. This makes it safer for long-term use and allows it to be used even if there are certain contraindications.

In general, clotrimazole is the preferred choice in the treatment of fungal infections due to its broad potency, rapid action, variety of formulations, and fewer side effects.

Side effects of nystatin and clotrimazole

Nystatin:

• Allergic reactions: possible skin rashes, itching, redness, swelling;
• Discomfort: some patients may experience discomfort, burning or heat at the site of application of the drug;
• Dry skin: Nystatin can cause dry skin, so moisturizers are recommended;
• Local irritations: in rare cases, redness, peeling or irritation may occur at the site of application of the drug;
• Indigestion: some patients may experience nausea, vomiting, or diarrhea after taking nystatin.

Clotrimazole:

1. Allergic reactions: possible skin rashes, itching, redness, swelling;
2. Skin burns: some patients may experience a burning sensation or burns at the site of application of the drug;
3. Local irritations: in rare cases, redness, peeling or irritation may occur at the site of application of the drug;
4. Dry skin: clotrimazole may cause dry skin, so moisturizers are recommended;
5. Vaginal burning: Some patients may experience vaginal burning or discomfort after using clotrimazole.

It should be noted that side effects may be different for each patient. If you experience any discomfort or reaction after using nystatin or clotrimazole, it is recommended that you consult your doctor or pharmacist.

Which drug to choose for certain symptoms

In the presence of symptoms of fungal infections of the skin and mucous membranes, it is important to choose the appropriate drug for effective treatment. The two most common drugs for the treatment of fungal infections – nystatin and clotrimazole – have their own characteristics and are recommended depending on the symptoms and the site of the lesion.

Nystatin is widely used to treat fungal infections of the skin and mucous membranes caused by Candida. The drug is available in various forms: ointment, cream, tablets, suspension. Nystatin has an antifungal effect and is effective in superficial infections of the skin and mucous membranes. It can be used to treat thrush, yeast dermatitis, and other fungal infections.

Clotrimazole is also an antifungal drug that can be used to treat fungal infections of the skin and mucous membranes. It is available in various forms: cream, ointment, solution. Clotrimazole is effective in the treatment of foot fungus, thrush and other fungal infections. It has a wide spectrum of activity and can be used to treat various types of fungal infections.

When choosing between nystatin and clotrimazole, it is important to consider the location of the lesion and the nature of the symptoms. For example, nystatin may be preferred in the treatment of fungal infections of the mucous membranes, such as thrush, while clotrimazole may be more effective in the treatment of fungal infections of the skin, such as foot fungus. It is important to consult your doctor or pharmacist to choose the most appropriate drug and dosage for your particular case.

Q&A:

Which drug is more effective: nystatin or clotrimazole?

Both drugs are effective in treating fungal infections, but the choice depends on the type of infection and the individual patient. Nystatin is commonly used to treat candidiasis, while clotrimazole can be used for various fungal infections of the skin and mucous membranes.

Which drug helps with fungal infections faster?

The speed of action of drugs may depend on the type of infection and the individual patient. In some cases, nystatin may be more effective and faster acting, in other cases, clotrimazole may show better results. It is better to consult a doctor to choose the most suitable drug.

What is the best drug to use to treat fungal infections in men?

For the treatment of fungal infections in men, the use of clotrimazole is generally recommended. This drug is effective in treating fungal balanitis (inflammation of the glans penis) and other fungal infections on the skin of the genitals.

Which drug is better to choose for the treatment of fungal infections in children?

Nystatin is generally recommended for the treatment of fungal infections in children. This drug is considered safe and effective for treating candidiasis in children, including fungal infections in the navel, mouth, and groin.

What is the best drug for the treatment of fungal infections of the vagina?

Clotrimazole is generally recommended for the treatment of fungal infections of the vagina. This drug is available as a cream or suppository and is indicated for the treatment of vaginal candidiasis (thrush) in women.

What is the best drug for the treatment of fungal infections of the nails?

Clotrimazole is generally recommended for the treatment of fungal nail infections. This medication is available as a cream or nail polish and can help clear up a fungal nail infection. In some cases, a systemic antifungal drug may be required.

Physicians’ advice on choosing a drug

When choosing between nystatin and clotrimazole for the treatment of fungal infections of the skin and mucous membranes, physicians recommend proceeding from the specific situation and characteristics of the patient.

Clotrimazole is a more commonly used drug that is effective against a wide range of fungal infections. It can be used to treat candidiasis of the skin, vagina, oral cavity, as well as to prevent relapses. Clotrimazole is available in various forms, including creams, ointments, solutions and suppositories, which allows you to choose the most convenient form of application for the patient.

Nystatin, on the other hand, is a narrow-spectrum drug that is only effective against Candida albicans. It has a high degree of safety and can be used even in pregnant and lactating women. Nystatin is available as a cream, ointment, and suspension.

When choosing a drug, doctors also take into account the individual preferences of the patient, his age, the presence of allergic reactions and other diseases. It is important to remember that self-treatment of fungal infections can lead to worsening of symptoms and complications. Therefore, before starting treatment, it is necessary to consult a doctor and follow his recommendations.

Video on the topic:

ranking of the top 5 inexpensive and effective products according to KP

From birth, our skin and mucous membranes are inhabited by billions of microorganisms, including fungi. They do not cause any harm to healthy people, but with a decrease in local immunity or a general weakening of the body, thrush or candidiasis may develop. This overgrowth of opportunistic fungi of the genus Candida provokes problems in the intimate area in girls and women.

Feelings in vaginal candidiasis are extremely unpleasant and irritating – this is burning and itching of the skin and mucous membranes, swelling and redness, cheesy discharge ¹ . This problem should be treated together with a doctor, since fungal activity is only a consequence of other body problems that need to be identified and treated.

After examining and confirming the diagnosis of vaginal candidiasis, the doctor will determine the tactics of treatment and select the best pills for thrush for women. In some cases, this may be a local therapy, involving the use of vaginal tablets or capsules, creams, gels. In advanced cases, severe symptoms or recurrent candidiasis, oral medications may be required to suppress the activity of fungi in the intestines and on the mucous membranes from the inside.

Many women make one common mistake. They try to cope with thrush with the help of folk remedies or use medications on their own, without taking into account the accompanying problems and the severity of the condition. This is the wrong approach! Although many drugs for fungal infections are sold without a prescription, it is important to see a doctor on time and be treated only under his direction.

List of top 5 tablets for thrush according to KP

Among all drugs against thrush, tablet forms stand out. They can be used both inside, orally, providing a systemic effect, and locally: they are introduced into the vagina and fight the reproduction of the fungus in the affected area.

Important! All drugs have side effects and contraindications. Our material is an overview and does not serve as a guide to action. Before buying drugs, consult your doctor.

Clotrimazole

Vaginal tablets for topical use contain the active ingredient of the same name. This broad spectrum antifungal agent helps to break down the cell membrane of fungi causing them to die ¹ .

It is active against dermatophytes, yeast-like and mold fungi, has an antimicrobial effect against gram-positive (staphylococci, streptococci) and gram-negative bacteria (gardnerella), as well as trichomoniasis pathogens. In addition to tablets, the product is available in the form of solutions for external use, ointments and creams.

Contraindications : hypersensitivity to clotrimazole, 1st trimester of pregnancy. It is not recommended to use vaginal tablets during menstruation.

Candide-B6

The drug for the treatment of thrush in women is available in the form of white biconvex tablets for vaginal use. The main active ingredient is clotrimazole, which has a broad-spectrum antifungal effect. The drug helps to cope with the main symptoms of candidiasis – itching, burning and cheesy discharge.

The agent is indicated for the treatment of vulvovaginal candidiasis, trichomoniasis, bacterial vaginitis and mixed infections of the vagina, as well as for the sanitation of the birth canal.

Contraindications : hypersensitivity to clotrimazole, 1st trimester of pregnancy. With caution: during lactation and in patients with hepatic insufficiency.

Flucostat

Antifungal drug is available in the form of white-pink gelatin capsules for oral administration. The active ingredient in the composition is fluconazole, which is also used in the treatment of thrush in women and men ¹ . It breaks the permeability of the cell membrane of the fungus, disrupting its growth and ability to reproduce.

The drug is indicated for the treatment and prevention of various candidiasis, including urogenital candidiasis, ringworm and onychomycosis.

Contraindications : hypersensitivity to fluconazole, other components of the drug, lactase deficiency, galactose intolerance, children under 3 years of age. With caution: with liver and kidney failure, some heart diseases. During pregnancy, it can be taken only with the permission and under the strict supervision of a doctor.

Natamycin

Antifungal antibiotic available as oral tablets, cream and vaginal suppositories. This substance has a combined effect on pathogenic microflora, especially fungi of the genus Candida: it destroys the cell membrane and causes its death.

The instructions indicate that the drug can be used to treat candidiasis in pregnant and lactating women. The main indications for admission include: vaginal candidiasis, oral candidiasis, intestinal candidiasis.

Contraindications : hypersensitivity to natamycin, galactose intolerance, lactase deficiency, age under 18 years.

Pimafucin

Antifungal available as oral tablets, vaginal suppositories and cream. The main active ingredient in the composition is an antibiotic of the macrolide group natamycin, which fights various types of fungal infection.

Main indications for prescription: candidal vaginitis, vulvitis, vulvovaginitis. During therapy, simultaneous treatment and sexual partner is important.

Contraindications : hypersensitivity to natamycin.

How to choose thrush pills for women

Today, pharmacies offer a wide selection of different drugs that are directed against fungal infections, including candida. For the treatment of thrush in women, antifungal drugs containing the following active substances are used: clotrimazole, natamycin, itraconazole, miconazole and butoconazole.

All drugs for the treatment of thrush in women are divided into two large classes:

• medicines that have a systemic effect on the body – they are taken orally and are in the form of capsules or tablets;
• topical medicines acting directly on the site of infection – these include creams, gels, ointments, solutions and vaginal suppositories (suppositories), soluble tablets or capsules.

When choosing tablets or other forms of drugs for thrush in women, you should consult your doctor. He can prescribe not only antifungal drugs, but also combined agents that restore the microflora, have an anti-inflammatory effect. The selection should be based on the following criteria:

• the main active ingredient that inhibits the growth of Candida fungi;
• dosage of the drug and the frequency of its administration, duration of the course;
• the rate of absorption of the components and the rapidity of the onset of the therapeutic effect;
• possible side effects;
• contraindications.

Popular questions and answers

pharmacist, teacher of pharmacology, editor-in-chief of MedCorr Olga Zorina answers popular questions regarding the choice of tablets for thrush for women.

Why can a woman get thrush?

– There are plenty of reasons for the development of fungal vaginitis. These are changes in the hormonal background during puberty, pregnancy, lactation, against the background of various health problems, endocrine pathologies (thyroid problems, diabetes mellitus).

Prolonged and irrational use of antibiotics, self-medication with various drugs, frequent douching with antiseptic solutions, change of sexual partners, stress and frequent SARS can provoke thrush.

Recurrent candidiasis is possible with immunodeficiencies, inflammatory processes in the female genital area, with strict diets, and obesity.

What should I do if a woman has thrush?

— The most important thing is not to treat yourself, but be sure to consult a doctor and confirm the diagnosis. Under the guise of thrush, many different infections can occur, including those that are sexually transmitted. In addition, candidiasis can be accompanied by bacterial vaginosis (violation of the vaginal microflora), so in parallel it is necessary to restore the balance of beneficial microbes.