Oral cortisone over the counter. Hydrocortisone vs Cortisone: A Comprehensive Comparison of Oral Corticosteroids

29.08.202112.07.2023 by alexxlab

What are the main differences between hydrocortisone and cortisone. How do these oral corticosteroids compare in terms of effectiveness, side effects, and cost. Which steroid is better suited for treating various inflammatory conditions.

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Understanding Hydrocortisone and Cortisone: Key Differences and Similarities

Hydrocortisone and cortisone are both mild corticosteroids used to treat various inflammatory conditions. While they share many similarities, there are some crucial differences between these two medications:

Availability: Hydrocortisone is available both over-the-counter (OTC) and by prescription, while cortisone is only available with a prescription.
Potency: Hydrocortisone is slightly more potent than cortisone, with 1 mg of hydrocortisone equivalent to 1.25 mg of cortisone.
Formulations: Hydrocortisone comes in various forms, including oral tablets, topical creams, lotions, ointments, and rectal suppositories. Cortisone is primarily available as oral tablets.
Activation: Cortisone is inactive until it’s converted to hydrocortisone in the liver, whereas hydrocortisone is already in its active form.

Both medications mimic the effects of naturally produced steroid hormones in the body, particularly cortisol, which has anti-inflammatory properties.

Conditions Treated by Hydrocortisone and Cortisone

These corticosteroids are used to treat a wide range of inflammatory conditions, including:

Allergic reactions
Respiratory conditions
Gastrointestinal diseases
Adrenal gland disorders
Rheumatic conditions
Skin inflammations (particularly for topical hydrocortisone)

Can hydrocortisone be used for skin irritations caused by poison ivy or insect bites? Yes, topical hydrocortisone is effective in relieving itching and inflammation associated with these conditions.

Efficacy Comparison: Hydrocortisone vs Cortisone

While both medications are effective in treating inflammatory conditions, hydrocortisone is generally considered more potent than cortisone. This is primarily due to cortisone’s need for conversion to hydrocortisone in the liver before becoming active.

Are there any clinical trials directly comparing hydrocortisone and cortisone? Currently, there are no specific clinical trials comparing the efficacy of these two medications for a particular condition. However, both are considered mild and short-acting compared to other corticosteroids like prednisone and triamcinolone.

Cost and Insurance Coverage: Making an Informed Decision

The cost and coverage of these medications can vary significantly:

Hydrocortisone: Generally covered by Medicare and other insurance plans. OTC versions may affect coverage. A tube of hydrocortisone cream can cost up to $30, but prescription versions with a discount card can be as low as $5.
Cortisone: Requires a prescription and is usually covered by Medicare and insurance plans. The average retail cost can be as high as $102 for 30 tablets, but discount coupons can reduce this to around $85.

How can patients reduce their out-of-pocket costs for these medications? Utilizing prescription discount cards, such as SingleCare, can significantly lower the cost of both hydrocortisone and cortisone.

Side Effects and Safety Considerations

Both hydrocortisone and cortisone can cause similar side effects, including:

Headache
Dizziness
Increased sweating
Flushing of the skin
Impaired wound healing
Muscle weakness
High blood pressure
Sodium and fluid retention (potentially leading to weight gain)

Are there any long-term risks associated with using these corticosteroids? Prolonged use of corticosteroids can lead to more serious side effects, including osteoporosis, cataracts, and increased susceptibility to infections. It’s crucial to use these medications under medical supervision and for the shortest duration necessary.

Drug Interactions and Precautions

Corticosteroids like hydrocortisone and cortisone can interact with various medications and conditions:

They may interact with blood thinners, increasing the risk of bleeding.
These medications can affect blood sugar levels, potentially complicating diabetes management.
Certain antibiotics and antifungal medications may increase the levels of corticosteroids in the body.

Should patients with a history of ulcers or gastrointestinal problems use these medications? Patients with a history of ulcers or other gastrointestinal issues should use corticosteroids with caution and under close medical supervision, as these medications can increase the risk of gastrointestinal complications.

Choosing Between Hydrocortisone and Cortisone: Factors to Consider

When deciding between hydrocortisone and cortisone, several factors should be taken into account:

The specific condition being treated
The desired route of administration (oral, topical, etc.)
The potency required for effective treatment
Individual patient factors, such as medical history and potential drug interactions
Cost and insurance coverage

Is one medication better suited for certain conditions than the other? While both medications are similar, hydrocortisone’s availability in various formulations (including topical forms) makes it more versatile for treating a wider range of conditions, particularly skin inflammations.

Topical Hydrocortisone: A Closer Look

Topical hydrocortisone deserves special mention due to its widespread use and availability over the counter:

It’s particularly effective for treating minor skin irritations, allergic reactions, and itching.
Topical hydrocortisone is considered a low-potency corticosteroid, making it suitable for short-term use on sensitive areas.
It’s available in various strengths, with higher concentrations requiring a prescription.

How long can topical hydrocortisone be used safely? For most minor skin conditions, topical hydrocortisone should not be used for more than 7 days without consulting a healthcare provider. Prolonged use can lead to skin thinning and other adverse effects.

Adrenal Suppression: A Concern with Corticosteroid Use

One significant concern with the use of corticosteroids like hydrocortisone and cortisone is the potential for adrenal suppression:

Long-term use can suppress the body’s natural production of cortisol.
This can lead to adrenal insufficiency, especially if the medication is stopped abruptly.
Symptoms of adrenal insufficiency include fatigue, weakness, and low blood pressure.

How can the risk of adrenal suppression be minimized? To reduce the risk of adrenal suppression, corticosteroids should be used at the lowest effective dose for the shortest possible duration. When long-term use is necessary, gradual tapering of the medication under medical supervision is crucial.

Monitoring and Follow-up

Regular monitoring is essential for patients using corticosteroids like hydrocortisone or cortisone, especially for extended periods:

Blood pressure should be regularly checked.
Blood sugar levels should be monitored, particularly in diabetic patients.
Bone density scans may be recommended for those at risk of osteoporosis.
Regular eye exams can help detect early signs of cataracts or glaucoma.

How often should patients on long-term corticosteroid therapy have follow-up appointments? Patients on long-term corticosteroid therapy should typically have follow-up appointments at least every 3-6 months, or more frequently if there are concerns about side effects or complications.

Special Populations: Considerations for Pregnant and Breastfeeding Women

The use of corticosteroids in pregnant and breastfeeding women requires careful consideration:

Corticosteroids can cross the placenta and may affect fetal development.
Some studies have suggested a slightly increased risk of cleft palate with first-trimester use.
Breastfeeding women should be aware that corticosteroids can pass into breast milk.

Are there safer alternatives for pregnant or breastfeeding women? In some cases, topical treatments or non-steroidal options may be preferred for pregnant or breastfeeding women. However, the decision should always be made in consultation with a healthcare provider, weighing the potential risks and benefits.

Pediatric Use

The use of corticosteroids in children requires special attention:

Growth suppression is a concern with long-term use in children.
Dosages may need to be adjusted based on the child’s weight and the condition being treated.
Topical hydrocortisone is generally considered safe for short-term use in children, but caution is advised.

How can the risk of growth suppression in children be minimized? To minimize the risk of growth suppression, corticosteroids should be used at the lowest effective dose for the shortest possible duration in children. Regular monitoring of growth and development is crucial for children on long-term corticosteroid therapy.

Alternative and Complementary Treatments

While corticosteroids like hydrocortisone and cortisone are effective for many conditions, alternative treatments may be considered in some cases:

Non-steroidal anti-inflammatory drugs (NSAIDs) for certain inflammatory conditions
Immunosuppressants for autoimmune disorders
Topical calcineurin inhibitors for certain skin conditions
Natural remedies like aloe vera or oatmeal baths for minor skin irritations

Can lifestyle modifications help reduce the need for corticosteroids? In some cases, lifestyle modifications such as dietary changes, stress reduction techniques, and regular exercise may help manage inflammatory conditions and potentially reduce the need for corticosteroid use. However, these should always be discussed with a healthcare provider and should not replace prescribed treatments without medical advice.

Combination Therapies

In some cases, corticosteroids may be used in combination with other treatments:

Combining corticosteroids with other medications can sometimes allow for lower doses of steroids.
For skin conditions, alternating between corticosteroids and non-steroidal treatments may help minimize side effects.
In some autoimmune conditions, corticosteroids may be used alongside disease-modifying drugs.

How can patients and healthcare providers determine the most effective combination therapy? The most effective combination therapy will depend on the specific condition being treated, the individual patient’s response, and potential drug interactions. Close monitoring and regular follow-ups are essential to optimize combination therapies.

Future Developments in Corticosteroid Therapy

Research in corticosteroid therapy continues to evolve, with several promising developments on the horizon:

Selective glucocorticoid receptor agonists (SEGRAs) aim to provide anti-inflammatory benefits with fewer side effects.
Novel drug delivery systems may improve the efficacy and safety of corticosteroid treatments.
Personalized medicine approaches may help tailor corticosteroid therapy to individual patient profiles.

How might these developments impact the use of hydrocortisone and cortisone in the future? While hydrocortisone and cortisone will likely remain important treatment options, future developments may provide alternatives with improved safety profiles or more targeted effects. This could potentially reduce the reliance on traditional corticosteroids for certain conditions.

In conclusion, both hydrocortisone and cortisone play crucial roles in managing various inflammatory conditions. While they share many similarities, their differences in potency, availability, and formulations can influence treatment decisions. Patients and healthcare providers should carefully consider the specific condition being treated, potential side effects, and individual patient factors when choosing between these medications. Regular monitoring and follow-up are essential to ensure safe and effective use of corticosteroids. As research continues, we may see new developments that further refine and improve corticosteroid therapy, potentially offering even more targeted and safer treatment options in the future.

Differences, similarities, and which is better for you

When it comes to steroids, hydrocortisone and cortisone are two options your doctor may recommend. Hydrocortisone and cortisone are mild corticosteroids that are mainly used to treat skin conditions, rheumatic diseases, and adrenal disorders.

Hydrocortisone and cortisone are man-made corticosteroid agents that mimic the effects of steroid hormones naturally produced in the body. The steroid hormones produced by the adrenal gland are mineralocorticoid (aldosterone), which plays a role in fluid retention, and glucocorticoid (cortisol), which has anti-inflammatory effects.

Despite their similarities in how they work, hydrocortisone and cortisone have differences in potency, formulation, and usage.

What are the main differences between hydrocortisone vs.

cortisone?

Hydrocortisone (What is Hydrocortisone?) is a generic corticosteroid that is available over-the-counter (OTC) or with a prescription. Brand names of hydrocortisone include Cortef, Cortizone, Anucort-HC, and Preparation H. Hydrocortisone is available as an oral tablet, topical cream, topical lotion, and topical ointment. It also comes as a rectal suppository.

Cortisone (What is Cortisone?) is a generic corticosteroid that is only available with a prescription. Cortisone is taken as an oral tablet and is sometimes known by its brand name, Cortone. Compared to hydrocortisone, cortisone is less potent. This is because cortisone by itself is inactive. After it’s administered, cortisone converts into hydrocortisone, or cortisol, in the liver.

Conditions treated by hydrocortisone vs. cortisone

Both hydrocortisone and cortisone can be used to treat inflammation from a variety of conditions. These corticosteroids can help treat inflammation from allergic conditions, respiratory conditions, gastrointestinal diseases, adrenal gland disorders, and rheumatic conditions. Since steroids are often used to target inflammatory symptoms, they may be used along with other drugs that treat the source of the problem.

Topical hydrocortisone is FDA approved to treat contact dermatitis or skin inflammation from an allergic reaction. Hydrocortisone can also be used to treat skin irritations and itchy symptoms after coming in contact with poison ivy or poison oak. For those who experience bad reactions to insect bites, topical corticosteroids like hydrocortisone can help relieve itchiness and inflammation.

Is hydrocortisone or cortisone more effective?

Hydrocortisone is slightly more potent than cortisone. When comparing doses, 1.25 milligrams of cortisone is equal to 1 milligram of hydrocortisone. Cortisone is inactive until it becomes hydrocortisone through processing in the liver. Since cortisone essentially is hydrocortisone, but with an extra step needed to make it active, it’s not prescribed as often.

Currently, there are no clinical trials that directly compare hydrocortisone and cortisone for a specific condition. Compared to other corticosteroids like prednisone and triamcinolone, hydrocortisone and cortisone are mild and short-acting. Compared to other topical corticosteroids, topical hydrocortisone is considered a low-potency corticosteroid.

It’s recommended to consult a healthcare provider for medical advice before purchasing OTC hydrocortisone. Otherwise, it’s necessary to visit a doctor in order to get a prescription for hydrocortisone or cortisone tablets.

Get the SingleCare prescription discount card

Coverage and cost comparison of hydrocortisone vs. cortisone

Generic versions of hydrocortisone are generally covered by Medicare and other insurance plans. Hydrocortisone can also be found over-the-counter so this may affect the coverage of some plans. A tube of hydrocortisone cream can run for as much as $30. If you have a doctor’s prescription and use a discount card, such as the SingleCare card, hydrocortisone can cost less than $5.

Cortisone tablets can only be purchased with a valid doctor’s prescription. Most Medicare and insurance plans will cover generic cortisone. The average retail cost of cortisone can be as high as $102. You can also use a SingleCare cortisone coupon to pay around $85 for a quantity of 30 tablets.

Common side effects of hydrocortisone vs. cortisone

Hydrocortisone and cortisone, like other corticosteroids, can cause similar side effects. Common side effects of hydrocortisone and cortisone include headache, dizziness, increased sweating, and flushing of the skin. Other side effects may include impaired wound healing, muscle weakness, and high blood pressure. The use of corticosteroids can also lead to sodium and fluid retention, which can manifest as weight gain.

Serious side effects of corticosteroids include allergic reactions or anaphylaxis. The risk of side effects is associated with the dose and duration of treatment. For this reason, hydrocortisone and cortisone are not recommended for long-term use. When used for longer periods of time, corticosteroids can lead to an increased risk of osteoporosis, or bone loss, and irregularities in the adrenal gland.

*not reported

This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more.

Source: DailyMed (Hydrocortisone), DailyMed (Cortisone)

Drug interactions of hydrocortisone vs. cortisone

Hydrocortisone and cortisone are processed in the liver by the CYP3A4 enzyme. Drugs that block, or inhibit, this enzyme can increase hydrocortisone or cortisone levels and increase the risk of side effects. By the same token, drugs that stimulate, or induce, this enzyme can decrease hydrocortisone or cortisone levels and lower their overall effectiveness.

Hydrocortisone and cortisone can interact with CYP3A4 inhibitors such as erythromycin, clarithromycin, isoniazid, and ketoconazole. Hydrocortisone and cortisone can also interact with CYP3A4 inducers such as rifampin, carbamazepine, and phenobarbital.

Since corticosteroids can increase blood sugar levels, dosing may need to be adjusted while taking antidiabetic drugs. Corticosteroids can also affect the blood levels of aspirin and anticoagulants like warfarin.

Corticosteroids can suppress the immune system. Therefore, live vaccines should be avoided while taking corticosteroids because of an increased risk of infection.

Consult a healthcare professional for other possible drug interactions.

Warnings of hydrocortisone vs. cortisone

Staying on corticosteroids for long periods of time can affect how well the adrenal gland is able to produce steroid hormones on its own. This can lead to secondary adrenal insufficiency, which is common after abrupt discontinuation of therapy. Therefore, treatment with corticosteroids should be tapered slowly to avoid possible withdrawal.

Corticosteroids should be used with caution if you have liver damage (cirrhosis) or an underactive thyroid (hypothyroidism).

Corticosteroids can suppress growth and development in children. In most cases, hydrocortisone and cortisone should be avoided in children. In some cases, children may be put on corticosteroids in controlled doses.

Using corticosteroids can increase the risk of infections. Corticosteroids can act as immunosuppressants, which can lower your body’s ability to fight off infections.

Consult your healthcare provider for other precautions while taking hydrocortisone or cortisone.

Frequently asked questions about hydrocortisone vs. cortisone

What is hydrocortisone?

Hydrocortisone is a corticosteroid used to treat inflammation caused by different conditions such as arthritis, asthma, and ulcerative colitis. Hydrocortisone is available in oral and topical forms. Topical hydrocortisone is used to treat contact dermatitis and other inflammatory skin diseases. Brand names of hydrocortisone include Cortef and Hydrocort.

What is cortisone?

Cortisone is a corticosteroid prescribed to treat inflammatory symptoms that occur from a variety of conditions. It is also known by the brand name Cortone, which has been discontinued. Cortisone is available as a 25 mg oral tablet that is usually taken multiple times per day for several days depending on the condition being treated.

Are hydrocortisone and cortisone the same?

Hydrocortisone and cortisone are identical short-acting corticosteroids. However, they are not the same. Cortisone is an inactive prodrug that is converted into hydrocortisone, or cortisol, in the liver. Hydrocortisone works as a topical medication whereas cortisone is not as effective as a topical treatment.

Is hydrocortisone or cortisone better?

Hydrocortisone is more potent than cortisone (1 mg of hydrocortisone is equivalent to 1.25 mg of cortisone). Hydrocortisone is also available over-the-counter as a topical cream, lotion, or ointment for skin conditions. Your doctor may prescribe hydrocortisone or cortisone after a complete evaluation of your condition.

Can I use hydrocortisone or cortisone while pregnant?

Low-dose corticosteroids may sometimes be used during pregnancy. However, because of their risk of side effects, such as high blood pressure, increased blood sugar levels, and fluid retention, corticosteroids should only be used if the benefits outweigh the risks. Consult a healthcare provider on the safety of corticosteroids during pregnancy.

Can I use hydrocortisone vs. cortisone with alcohol?

Corticosteroids and alcohol are not generally recommended to be taken together. Drinking alcohol regularly can alter blood sugar levels and affect the immune system. The side effects of corticosteroids and alcohol can overlap and lead to harmful situations.

Is hydrocortisone a corticosteroid?

Hydrocortisone is a synthetic corticosteroid. Its effects mimic those of the naturally produced glucocorticoid, cortisol. Compared to other corticosteroids, hydrocortisone is considered a low-potency corticosteroid.

What does cortisone treat?

Cortisone is used as an anti-inflammatory and immunosuppressant drug. It can treat inflammation from skin diseases, lung conditions, autoimmune disorders, and infections. Cortisone can also be used to treat allergic reactions and severe asthma episodes.

Cortisone, Oral Tablet

Highlights for cortisone

Cortisone oral tablet is only available as a generic drug. It doesn’t have a brand-name version.
Cortisone only comes as a tablet you take by mouth.
Cortisone oral tablet is used to treat a variety of conditions. These can include adrenocortical insufficiency, arthritis, allergies, and ulcerative colitis. It’s also used to treat anemia, lupus, and skin conditions, including severe psoriasis.

Chickenpox and measles warning: This drug can weaken your body’s ability to fight infections. Try to stay away from people who have chickenpox or measles, especially if you haven’t been vaccinated or haven’t had these diseases before. Call your doctor right away if you have contact with anyone who has these diseases while you’re taking this drug.
Infections warning: You shouldn’t take this drug if you have an infection. These include fungal, bacterial, or viral infections. Cortisone can weaken your body’s response to infections. This means that your infection may be severe or even fatal (cause death). This drug can also cover up symptoms of infection. If you have any signs of infection, call your doctor right away.

Cortisone oral tablet is a prescription drug. It’s only available as a generic drug.

Why it’s used

Cortisone helps to decrease inflammation and immune responses. It can also be used as replacement therapy for certain hormones.

This drug is used to treat several conditions. These include:

adrenal insufficiency
arthritis, including osteoarthritis and rheumatoid arthritis
allergic conditions, such as seasonal allergies
asthma
ulcerative colitis
anemia
lupus
skin conditions, such as severe psoriasis

How it works

Cortisone belongs to a class of drugs called glucocorticoids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Cortisone is a steroid drug. It helps decrease swelling and inflammation in your body. It works by stopping the release of molecules that cause inflammation. This also stops your body from having an immune response.

Cortisone oral tablet doesn’t cause drowsiness. However, it can cause other side effects.

More common side effects

The more common side effects of cortisone can include:

confusion
excitement
restlessness
headache
nausea
vomiting
skin problems, including:
- acne
- thin skin
- heavy sweating
- redness
trouble sleeping
weight gain

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Allergic reactions. Symptoms can include:
- skin rash
- itching
- hives
- swelling of your face, lips, or tongue
Fluid and electrolyte problems. These can include:
- fluid retention
- heart failure, with symptoms such as:
  - shortness of breath
  - fast heart rate
  - swelling of your arms and legs
- high blood pressure
Muscle problems. Symptoms can include:
- muscle weakness
- broken bones in your spine
- osteoporosis
- tendon rupture
Stomach problems. These can include:
- peptic ulcer, with symptoms such as:
  - upper stomach pain
  - black, tarry stools
- pancreatitis (inflammation of the pancreas), with symptoms such as:
  - upper stomach pain
  - nausea
  - vomiting
Slowed growth in children
Glaucoma. Symptoms can include:
- blurry vision
- double vision
- eye pain
Convulsions

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Cortisone oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with cortisone are listed below.

Drugs you should not use with cortisone

Do not receive live vaccines while you’re taking cortisone. Examples of these drugs include:

live flu vaccine
measles, mumps, and rubella vaccine (MMR)

If you receive a live vaccine, your body might not be able to build up resistance to the virus in the vaccine. The virus can spread in your body and cause an infection.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Cortisone oral tablet comes with several warnings.

Allergy warning

Cortisone can cause a severe allergic reaction. Symptoms can include:

skin rash
itching or hives
swelling of your face, lips, or tongue

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Warnings for people with certain health conditions

For people with infections: Don’t take this drug if you have a fungal, bacterial, or viral infection. Cortisone can weaken your body’s response to infections. This can be severe or fatal. The drug can also cover up the symptoms of an infection.

For people with high blood pressure or heart problems: This drug can raise your blood pressure. It can also make heart conditions worse.

For people with diabetes: Ask your doctor if this drug is safe for you. Cortisone can increase your blood sugar. You may need to test your blood sugar level more often. Your doctor may also change the dosage of your diabetes drugs.

For people with glaucoma or eye problems: This drug increases your risk of eye infections. Ask your doctor if this drug is safe for you.

For people with stomach or intestinal problems: This drug can irritate your stomach and intestines. This can make your condition worse. Ask your doctor if this drug is safe for you.

For people with liver problems: Ask your doctor if this drug is safe for you. It may make your liver problems worse.

For people with kidney problems: Ask your doctor if this drug is safe for you. It may make your kidney problems worse.

For people with seizures: Ask your doctor if this drug is safe for you. It may make your condition worse.

For people with psychiatric and mood disorders: Ask your doctor if this drug is safe for you. It may make your condition worse.

Warnings for other groups

For pregnant women: There has not been enough research done on the use of cortisone in pregnant women. Talk to your doctor if you’re pregnant or plan to become pregnant. Ask your doctor to tell you about the specific harm that may be done to the fetus. This drug should only be used if the potential risk is acceptable given the drug’s potential benefit.

Call your doctor right away if you become pregnant while taking this drug.

For women who are breastfeeding: This drug may pass into breast milk and cause side effects in a child who is breastfed. These side effects include slowed growth and development. Talk to your doctor about breastfeeding your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For children: It has not been confirmed that cortisone is safe and effective for use in people younger than 18 years.

This dosage information is for cortisone oral tablet. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

your age
the condition being treated
how severe your condition is
other medical conditions you have
how you react to the first dose

Forms and strengths

Generic: Cortisone

Form: Oral tablet
Strengths: 25 mg

Dosage for all conditions

Adult dosage (ages 18 years and older)

Typical dosage: 25–300 mg per day. Your doctor will decide your dosage depending on your condition.

Child dosage (ages 0–17 years)

Cortisone has not been confirmed as safe and effective for use in people younger than 18 years.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Cortisone oral tablet is used for both short-term and long-term treatment. The length of your treatment will depend on your condition. It comes with risks if you don’t take it as prescribed.

If you stop taking this drug suddenly or don’t take it at all: You may have withdrawal symptoms if you stop taking this drug suddenly. If you need to stop taking it, your doctor will slowly reduce your dosage over time.

If you don’t take this drug at all, your condition won’t be treated and may get worse.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

insomnia (trouble falling or staying asleep)
nervousness
increased appetite
indigestion

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take it as soon as you remember. If it’s almost time for your next dose, call your doctor or pharmacist. You might need to miss a dose or take an extra dose depending on the condition you’re treating. Don’t take an extra dose without checking with your doctor or pharmacist.

How to tell if the drug is working: You should have fewer symptoms and decreased inflammation.

Keep these considerations in mind if your doctor prescribes cortisone oral tablet for you.

General

Take cortisone with food and a glass of water. This may help reduce upset stomach.
Take this drug in the morning.
You can cut or crush the oral tablet

Storage

Store cortisone at room temperature. Keep it between 68°F and 77°F (20°C and 25°C).
Keep this drug away from light.
Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
Don’t worry about airport X-ray machines. They can’t hurt your medication.
You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you.
Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Clinical monitoring

You and your doctor should monitor certain health issues during your treatment. This can help make sure you stay safe while you take this drug. These issues include:

blood pressure levels
blood sugar levels (if you have diabetes)
potassium levels

Your diet

This drug may cause you to retain salt and water. It may also affect your potassium levels. Your doctor may tell you to take potassium supplements or reduce how much salt you eat.

Availability

Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

What is a yeast infection?

Most healthy women have yeast in their vagina. But sometimes the yeast grows too strong and leads to infection. Yeast infections can be very annoying and unpleasant.

What causes yeast infections?

Vaginal yeast infection, also sometimes called vulvovaginal candidiasis, occurs when the healthy yeast that normally lives in the vagina gets out of control. This often results in itching and other annoying symptoms. The medical name for a yeast infection is “ candidiasis ” because they are usually caused by a type of yeast called candida.

When the immune system is reduced, the normal yeast that lives in the vagina can grow too large and lead to infection. Causes that may cause changes in your vaginal environment:

normal changes in hormone levels (as during the menstrual cycle)
antibiotics, cortisone and other drugs
pregnancy
diabetes mellitus
weak immune system
natural reaction to another person’s genital chemistry

Yeast infections can also occur on the penises and scrotum, but not as often. They can cause redness and irritation on your penis or scrotum.

Yeast infections are not STDs (these are infections that are passed from one person to another during vaginal, anal and oral sex). They are not contagious and cannot be passed on to another person during sex. But sexual contact sometimes leads to yeast infections—your body chemistry can react to the other person’s natural genital yeast and the bacteria that causes the yeast to grow.

People can also get a yeast infection in their mouth, throat, or tongue—this is called thrush.

What are the symptoms of a yeast infection?

Yeast infections often cause a curdled, white, lumpy vaginal discharge that usually does not smell (or smells only slightly different than usual).

Most yeast infections result in itching, burning and/or redness in or around the vagina. Vaginal itching usually gets worse the longer you have the infection. Sex may be uncomfortable or painful. In extreme cases, you may get cracks or sores on your vagina or vulva. If you have severe irritation, you may experience pain when urinating.

How to treat yeast infections?

Yeast infections can usually be easily treated in a few days with an antifungal medication. You can purchase medicated creams or suppositories for yeast infections.

Be sure to follow instructions and take all medicines, even if your symptoms go away before you are done. You can also treat yeast infections with one tablet (diflucan or fluconazole). Need a prescription from a doctor to get a yeast infection pill.

Do not have vaginal or oral sex until you have completed treatment and the infection has gone. Friction from sex may cause more irritation or make treatment more difficult. Some medications you use inside your vagina contain oil, which can cause condoms to break.

Even though yeast infections can be very itchy, try not to scratch the itch. This can aggravate irritation or scratch the skin, through which germs can spread and lead to more infections. There are over-the-counter creams that can be used on the vulva to soothe irritation. Your doctor can also give you tips to relieve burning and itching.