How does sertraline affect weight. What are the common side effects of sertraline. Can sertraline help with anxiety and depression. How long does it take for sertraline to work. What are the experiences of long-term sertraline users.

Understanding Sertraline: An Overview of the Antidepressant Medication

Sertraline, commonly known by its brand name Zoloft, is a widely prescribed antidepressant medication belonging to the selective serotonin reuptake inhibitor (SSRI) class. While primarily used to treat depression, anxiety disorders, and other mental health conditions, some individuals have reported weight loss as a side effect of sertraline use.

This medication works by increasing the levels of serotonin, a neurotransmitter associated with mood regulation, in the brain. By balancing serotonin levels, sertraline aims to alleviate symptoms of depression and anxiety, potentially improving overall quality of life for many patients.

How does sertraline affect weight?

The relationship between sertraline and weight changes can vary among individuals. Some users may experience weight loss, particularly in the initial stages of treatment, while others might observe weight gain over time. The exact mechanisms behind these weight fluctuations are not fully understood, but they may be related to changes in appetite, metabolism, or lifestyle factors influenced by improved mental health.

Sertraline’s Effectiveness in Treating Depression and Anxiety

Many users have reported significant improvements in their mental health after starting sertraline treatment. One reviewer described their experience as life-changing, stating, “It changed my life. I’m no longer sad, my anxiety is completely under control. I can sit down and watch a TV show, I no longer have panic attacks from my anxiety, I’m happy, I wake up feeling positive, I can finally enjoy my life.”

How long does it take for sertraline to work?

The onset of sertraline’s therapeutic effects can vary from person to person. Some individuals may notice improvements within a few weeks, while others might require several months to experience the full benefits. One user reported, “I think it took about three months before I noticed major improvements with this med.” It’s important to maintain patience and consistent use as prescribed by a healthcare professional to achieve optimal results.

Common Side Effects and User Experiences with Sertraline

Like all medications, sertraline can cause side effects. These may include:

• Nausea
• Dizziness
• Drowsiness
• Insomnia
• Dry mouth
• Changes in appetite
• Sexual dysfunction

One user reported developing bruxism (teeth grinding) as a side effect and inquired about its prevalence among sertraline users. While this is not one of the most commonly reported side effects, it underscores the importance of discussing any unusual symptoms with a healthcare provider.

Are there any serious side effects associated with sertraline use?

While rare, some individuals may experience more severe side effects such as serotonin syndrome, increased risk of bleeding, or changes in heart rhythm. It’s crucial to seek immediate medical attention if any concerning symptoms arise during treatment.

Sertraline Dosage and Administration: Tips for New Users

Sertraline is typically prescribed in tablet form, with dosages ranging from 25mg to 200mg daily, depending on the individual’s condition and response to treatment. A long-term user shared some valuable tips for those new to sertraline:

1. Always take it after eating a meal
2. Take it with a full glass of water to prevent throat irritation
3. Try to take it at the same time every day for consistent effects

These suggestions can help minimize potential side effects and ensure optimal absorption of the medication.

Can sertraline be taken with other medications?

Sertraline may interact with certain medications, including other antidepressants, blood thinners, and some pain relievers. It’s essential to inform your healthcare provider about all medications, supplements, and herbal products you’re taking to avoid potential interactions.

Long-term Use of Sertraline: Benefits and Considerations

Many individuals find long-term use of sertraline beneficial for managing their mental health conditions. One user reported being on a 25mg dose for six years with continued positive effects. However, it’s important to note that everyone’s experience with medication can differ.

Is it possible to develop tolerance to sertraline over time?

While some individuals may maintain the same dose for years with continued effectiveness, others might require dose adjustments over time. Regular follow-ups with a healthcare provider can help monitor the medication’s efficacy and make necessary adjustments.

Discontinuing Sertraline: Tapering and Potential Withdrawal Effects

When deciding to stop sertraline treatment, it’s crucial to do so under medical supervision. Abruptly discontinuing the medication can lead to withdrawal symptoms, which may include:

• Dizziness
• Nausea
• Irritability
• Headaches
• Flu-like symptoms

One user shared their experience of tapering off sertraline: “Been taking Sertraline for many years and now trying to get off of it. We have been doing this for quite a few months. I originally was at 100mg and now I am at 25mg.”

How should one taper off sertraline safely?

A gradual reduction in dosage, typically over several weeks or months, is recommended to minimize withdrawal effects. The tapering schedule should be determined by a healthcare provider based on the individual’s current dose, duration of treatment, and overall health status.

Comparing Sertraline to Other Antidepressants: User Perspectives

While sertraline is effective for many individuals, it may not be the ideal choice for everyone. Some users have found better results with other antidepressants. One reviewer shared their experience: “I have since switched to citalopram and felt a huge positive difference within 2 weeks. It felt so gentle. I wasn’t so exhausted and had energy again. Plus my anxiety has practically disappeared.”

How do SSRIs differ from other types of antidepressants?

SSRIs like sertraline primarily target serotonin, while other classes of antidepressants may affect different neurotransmitters or combinations thereof. The choice of medication often depends on individual factors, including symptoms, medical history, and potential side effects.

Sertraline and Its Impact on Daily Life: Work, Relationships, and Overall Functioning

Many users report significant improvements in their daily functioning after starting sertraline treatment. One reviewer described their transformation: “I had panic disorder and OCD, and my panic disorder was so bad I could not leave the house at all. Now, I almost never get panic attacks, work a high-stress job without issue, and am able to be in public by myself.”

This improvement in daily functioning can have far-reaching effects on an individual’s quality of life, potentially enhancing work performance, social relationships, and overall well-being.

Can sertraline help with social anxiety?

Yes, sertraline is often prescribed for social anxiety disorder. Many users report reduced anxiety in social situations, improved confidence, and better ability to engage in public activities after starting treatment.

The Importance of Individualized Treatment: Finding the Right Medication and Dosage

It’s crucial to recognize that the effectiveness and side effects of sertraline can vary significantly from person to person. What works well for one individual may not be the best option for another. This variability underscores the importance of working closely with a healthcare provider to find the most suitable treatment plan.

One user emphasized their sensitivity to medication: “I am very sensitive to medication, so I find if I don’t take my Zoloft in the same 2ish hour window every day, I do get some pretty annoying side effects for a week (brain fog, depression, panic attacks).” This highlights the need for personalized approaches to medication management.

How can one determine if sertraline is the right medication?

Determining the most effective antidepressant often involves a process of trial and adjustment. Factors such as symptom improvement, side effect profile, and overall tolerance to the medication are considered. Regular communication with a healthcare provider is essential to assess progress and make necessary adjustments.

Combining Sertraline with Other Treatment Modalities: A Holistic Approach to Mental Health

While sertraline can be highly effective in managing depression and anxiety symptoms, many healthcare professionals recommend a multi-faceted approach to mental health treatment. This may include combining medication with psychotherapy, lifestyle changes, and other supportive interventions.

Can sertraline be used in conjunction with therapy?

Yes, many individuals find that combining sertraline with psychotherapy, such as cognitive-behavioral therapy (CBT), provides a synergistic effect in managing their mental health conditions. The medication can help alleviate symptoms, while therapy provides tools and strategies for long-term coping and personal growth.

Additionally, lifestyle factors such as regular exercise, a balanced diet, adequate sleep, and stress management techniques can complement the effects of sertraline and contribute to overall mental well-being.

Sertraline and Special Populations: Considerations for Pregnancy, Elderly, and Adolescents

The use of sertraline in special populations requires careful consideration and close medical supervision. Pregnant women, elderly individuals, and adolescents may have unique needs and potential risks associated with sertraline use.

Is sertraline safe during pregnancy?

The safety of sertraline during pregnancy is a complex issue that requires individualized assessment. While some studies suggest minimal risk to the fetus, others have identified potential concerns. Pregnant women or those planning to become pregnant should discuss the risks and benefits of sertraline use with their healthcare provider to make an informed decision.

For elderly patients, dosage adjustments may be necessary due to changes in metabolism and increased sensitivity to medications. In adolescents, careful monitoring is essential as some studies have suggested a potential increase in suicidal thoughts in young people taking antidepressants.

The Role of Patient Education and Support in Sertraline Treatment

Proper education about sertraline, its effects, and potential side effects is crucial for successful treatment. Patients who are well-informed about their medication are better equipped to manage their treatment, recognize potential issues, and communicate effectively with their healthcare providers.

Where can patients find reliable information about sertraline?

Reliable sources of information include healthcare providers, pharmacists, reputable medical websites, and patient support groups. It’s important to seek information from credible sources and discuss any concerns or questions with a healthcare professional.

Support from family, friends, and mental health professionals can also play a significant role in the success of sertraline treatment. Many users find that a strong support system helps them navigate the challenges of mental health treatment and maintain consistency in their medication regimen.

Future Directions in Antidepressant Treatment: Beyond Sertraline

While sertraline remains a widely prescribed and effective antidepressant for many individuals, ongoing research continues to explore new treatments and approaches to mental health care. These may include novel medications targeting different neurotransmitter systems, personalized medicine approaches based on genetic profiles, and innovative non-pharmacological interventions.

What new developments are on the horizon for depression and anxiety treatment?

Emerging areas of research include ketamine-based treatments for treatment-resistant depression, psychedelic-assisted therapy, and advanced neuroimaging techniques to guide treatment selection. Additionally, there is growing interest in the role of gut microbiota in mental health, leading to investigations into potential probiotic or dietary interventions.

As our understanding of mental health conditions evolves, so too will the approaches to treatment. While sertraline continues to be a valuable tool in the management of depression and anxiety, future advancements may offer even more targeted and personalized treatment options for individuals struggling with mental health concerns.

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I have been a “highly funtioning” depressed person for many years: life of the party, witty, intelligent, charming, intelligent conversationalist, highly successful at the top of the food chain in my field, …until I got home. Work was an escape from myself for me. If I had no weekend functions to attend I would be catatonic, only getting out of bed to use the bathroom. I had always felt like a…

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SORT BY Condition: Depression

Overall rating 5.0

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Seemed to have no side effects. Been taking Sertraline for many years and now trying to get off of it. We have been doing this for quite a few months. I originally was at 100mg and now I am at 25mg. Want to know what side effects should I be experiencing as I am coming off of sertraline.

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Fill 3Created with Sketch. Condition: Anxiousness associated with Depression

Overall rating 3.0

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Developed bruxism (grinding of the teeth). How common is it as a side effect of sertraline?

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Fill 3Created with Sketch. Condition: Anxiousness associated with Depression

Overall rating 5.0

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Iv always battled with anxiety and depression. Anxiety so bad I couldn’t think straight I couldn’t function I would talk super fast eat fast never sit down my brain was always running around and nothing could ever slow it down it would give me panic attacks my depression was always also so bad I would cry daily and hide it from anyone my childhood trauma wouldn’t let me just breath everyday waking up was sad for me because it would be another day of anxiety and depression I didn’t wanna live that way anymore thoughts of taking my life was what I thought could end the feeling or pure pain until I started this medication it changed my life I’m no longer sad my anxiety it completely under control I can sit down and watch a tv show I no longer have panic attacks from my anxiety I’m happy I wake up feeling positive I can finally enjoy my life I’m truly grateful for this medication. Read More Read Less

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Fill 3Created with Sketch. Condition: Repeated Episodes of Anxiety

Overall rating 1. 3

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I HAVE HAD ANXIETY SINCE MY TEENS BUT HAVE ONLY SOUGHT HELP FROM MY DOCTOR IN THE LAST FEW MONTHS ( I’m 56 now )I WAS PRESCRIBED 50 mg AND THE SIDE EFFECTS WERE HORRENDOUS. I WAS SLEEPING A LOT DURING THE DAY, COULD NOT FUNCTION AND FELT SO SPACED OUT.I STUCK AT IT FOR 9 WEEKS BEFORE I COULD TAKE NO MORE.
LOADS OF PEOPLE IN THE REVIEWS SAID IT TAKES A GOOD 4 WEEKS BEFORE IT KICKS IN. UNFORTUNATELY IT DID NOTHING FOR ME. A LOT OF MY FRIENDS SAY IT WORKS GREAT THEM .
I HAVE SINCE SWITCHED TO CITALOPRAM AND FELT A HUGE POSITIVE DIFFERENCE WITHIN 2 WEEKS. IT FELT SO GENTLE.
I WASNT SO EXHAUSTED AND HAD ENERGY AGAIN.PLUS MY ANXIETY HAS PRACTICALLY DISAPPEARED.Read More Read Less

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

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I am a twenty-five year old female, and I’ve been on Zoloft 25mg for about six years. I had panic disorder and OCD, and my panic disorder was so bad I could not leave the house at all. Now, I almost never get panic attacks, work a high stress job without issue, and am able to be in public by myself. It was such a lifesaver for me. Honestly, the side effects are annoying in the beginning, but I think mine went away after about a month. I am very sensitive to medication, so I find if I don’t take my Zoloft in the same 2ish hour window every day, I do get some pretty annoying side effects for a week (brain fog, depression, panic attacks) – but that’s only if I don’t remember to take it on time; and again I’m someone who is very sensitive to medication.
My tips if you’re new to this medication: always take it after eating a meal, always take it with a FULL glass of water/at least half a water bottle (it can burn your throat if you don’t drink enough with it – never ever dry swallow or only take just a sip of water), try really hard to take it the exact same time every single day. I think it took about three months before I noticed major improvements with this med. I’m still amazed that I’m only on 25mg after six years! I was worried about dependency/having to increase dosage constantly, but I think once you find your dose of this med, you won’t have to increase for a long time.Read More Read Less

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Fill 3Created with Sketch. Condition: Depression

Overall rating 5.0

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Sertraline was my second attempt at antidepressants (1st was Effexor, very bad reaction from day 1). I can’t believe how lucky I am that it works for me. Mood, sleep and anxiety levels improved greatly. I have GAD as well, so the first week or two anxiety was getting worse, but now I rarely get it anymore. Depression is harder to lift as it turns out I’ve had it for a couple of decades almost nonstop, but this is the first time in my life that I don’t think I would be better off dead. This medication is the best thing that happened to me in my entire life. It doesn’t make me feel euphoric or anything, I just don’t feel bad for no reason all the time as I did before. Read More Read Less

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Fill 3Created with Sketch. Condition: Posttraumatic Stress Syndrome

Overall rating 5.0

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I have struggled with anger and depression most of my life. I have tried different medications with various results. This medication (Sertraline) has been a life savor for me. I no longer get made at the drop of a hat and things don’t bother me as much. Can I get mad? Sure, just like anyone but it is a very rair occasion. My wife and kids have seen a significant improvement with my mood. I feel “normal” now and like my life.

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Fill 3Created with Sketch. Condition: Major Depressive Disorder

Overall rating 3.7

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Been taking this for about 3 months now. It’s helped a lot with my major depression and anxiety, but oh my God, do not ever order tablets over 100mg. What are 200mg tablets made with for these insane prices, dinosaur blood? Woolly mammoth bones? Absolutely unreal.

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Fill 3Created with Sketch. Condition: Depression

Overall rating 5.0

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The first week was rough, but I noticed a positive change in my relationships as well as not nice physical side effects. All seemed very good after 3 weeks. Depression lifted. Feel v grateful. Now realise how depressed I’ve been.

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Fill 3Created with Sketch. Condition: Major Depressive Disorder

Overall rating 2.3

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I went to a mental hospital for 7 days because of self harm and after 3 days they said i had major depression i was on it for 2 weeks then got taken off of it and 2 months later was put on it for a month. This medication has not done anything and i still feel the same as before.

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Fill 3Created with Sketch. Condition: Depression

Overall rating 1.7

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I took 25 mg the first night and I could not fall asleep. The second night, I took two pills and still could not sleep. The third night, I took 3 pills and it had no effect at all. I stopped taking this prescription.
I told my doctor, I have trouble sleeping and why she prescribed sertraline that treats depression, I do not understand. After reading some of the bad reviews, I would not take this medicine even if she increased the dose.

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Fill 3Created with Sketch. Condition: Anxiousness associated with Depression

Overall rating 4.3

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At first I didn’t know if it was working or only a placebo effect. But it would be good for like a day or two then go back to how it was… now I’ve been on 100mg for a month now and I’ve noticed a change! I used to have all the possible emotions in a day and the extremes too! I used to want to kill myself everyday. Now my emotions are wayyyy better. I don’t have a rollercoaster of emotions everyday. I don’t want to kill myself everyday now it’s fun. I really appreciate the help it gave me so I can work on what is actually going on inside and work through my traumaRead More Read Less

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Fill 3Created with Sketch. Condition: Depression

Overall rating 4.3

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Hang in there this medication is a game changer for me. Took 6 week but then one day just like that i could feel the difference and finally feel normal again.I ?? ??

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Fill 3Created with Sketch. Condition: Bipolar Depression

Overall rating 4.3

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At first I was extremely hesitant, especially since I was only in grade 10 and was terrified of the possible side effects. Of course, the first week was the worst- but I only vomited on the first day. It seems Sertraline has caused me to also lose 15lbs. I went from being 95lbs all the way down to 85lbs. I’m 18 now and have been on it for 3 years and its worked quite well. My feelings of suicide and depression have unfortunately made its comeback so my doctor suggested I go on 100mg to help. Overall, I’d give this medication an 8/10. Its easy to use, the side effects aren’t terrible- so give it a chance before you completely give it up. It takes a bit to work as well (3 months for me) so be patient. I feel as if I’ve also become resistant to it as well (hence why I’m feeling depressed again). If you’re reading this and you’re scared, trust me- it’ll be okay! If it doesn’t work for you, you can always try something else.Read More Read Less

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Fill 3Created with Sketch. Condition: Other

Overall rating 3. 7

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I’m taking this for generalised anxiety disorder which doesn’t seem to be on the list. I was very hesistant to take this medication when I first prescribed it, because I read a lot of bad reviews. My advice if you’re prescribed this is to give it a chance to work. The first about 2 weeks I was on this my anxiety was a lot worse, but after about a month it started to help it. I went up from 50mg to 100mg per day after being on it for about 3 months and the 100mg dose has been a lot more effective. I’ve been on sertraline for just over a year now and it’s definitely not a cure but along with therapy has helped me manage my symptoms. I still get regular anxiety and have bad moments but I definitely have less very particularly bad moments. I mean I haven’t had a panic attack in like 6 months and was getting them almost once a week at one point. Read More Read Less

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Fill 3Created with Sketch. Condition: Depression

Overall rating 3.0

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I’m currently on 200mg a day and while I feel it may have helped me in the beginning just a bit, I still feel close to the same I did 6 months ago when I finally got on govt assisted health insurance when I finally decided to try to get some help. I suffer from Charcot Marie-Tooth (CMT) which is a degenerative nerve disorder. I’d say I had a great childhood and teen group growing up since it didn’t really become an issue until I was about 14-15 when I was diagnosed. The issues really started to affect my life in my early 20’s where I began struggling with things I was once able to do and my fingers were clawing up into my palms. I always tried to have a positive attitude about the situation and reminded myself I have it a lot better than other people, but I began to feel like I would become a burden to people later on in life when it get’s to the point I have trouble walking (which is what I’m experiencing now). I subconsciously began separating myself from friend group functions and I’ve never been in a relationship longer than 6 months because CMT is hereditary and most girls are wanting to find someone that can protect, support, and have kids with. I don’t want my kids or grandkids to go through what I have so I’d have to find someone very particular and since I’ve been unemployed for almost a year now and don’t have much to do, the depression has gotten to the worst I’ve ever had it. I think sertraline is a great start for doctors to go with, but if you are having some severe depression you may need to try something else. I have been on sertraline for about 6 months and just started welbutrin and will switch from the sertraline to lexapro. So, my full daily intake will be 62mg of methadone (opiates were what allowed me to somehow work two jobs for 5-6 years in my twenties but with tolerance growth/ cost of pills/ withdrawal symptoms I decided to get into treatment) (The highest I went was 84mg, then went down to 70mg and am now down to 62mg, I’d like to get off it so I can see how my body feels by only taking doctor prescribed prescriptions), 400mg gabapentin x3/per day, cyclobenzaprine (flexiril) 10mg x3/day, 200mg Sertraline (zoloft) once a day, and now Bupropion HCL (Welbutrin) 150mg once a day. Sorry for the novella, but this could also be a reason the sertraline just didn’t do the trick for me, but could see it working for someone suffering from just slight depression instead of in my case I’m struggling now and if it’s only going to get worse what’s the point in trying if you are suffering.Read More Read Less

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Fill 3Created with Sketch. Condition: Obsessive Compulsive Disorder

Overall rating 5.0

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I had OCD my whole life only I didnt know what it was. I also have depression anxiety and panic. I’ve been taking 100 mg Zoloft for 20 years it has saved my life I believe. Lately life got the best of me loss after loss for the past 5 years. My dr recently put me up to 150 I’m much better and will stay on this dose. My advice to anyone needing help don’t hesitate to take this medication. If I remember At first it takes some getting use to but stick with it you will be glad you did.

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Fill 3Created with Sketch. Condition: Anxiousness associated with Depression

Overall rating 5.0

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Sertraline has been a life saver for me. I have been on it for about 2 months now. It took about 1 month to feel the full effects. I take a very small dosage (25mg) and it really takes the edge off my anxiety and depression, just makes me happier and calmer overall and more social, productive, creative. The side effects have pretty much gone away. At first, I noticed a lot of yawning and for about 5 weeks it was very difficult to have an orgasm, but that went away and now my sex life is humming along again, and I actually think I feel more desire because I’m less anxious/depressed. Highly recommend, and try to stick with it for at least 6 weeks – the side effects will get better. Read More Read Less

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Fill 3Created with Sketch. Condition: Depression

Overall rating 5.0

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So many negative reviews. I’m on setriline for one week. I took 25mg for four days then went up to 50 mg. Simple side effects first. Feeling a little hot, not a big deal, a few hours after taking the medication you may feel a little anxious but still not a big deal. Positive effect, higher sex drive, talking faster because my thoughts are not intrusive, an absolute boost in energy even if you lack sleep, the negative thoughts literally are blocked out and you are unable to focus on them. When normally feeling anxious around others, now I can talk and join in and laugh with no anxiety, sleeping less but that’s because I have a boost of energy now. Listen, if you are listening to the negative reviews then look up the negative side effects of a simple pain killer, it’s all the same! Even though you are fine on pain killers. Side effects are nothing compared to the positive effects from what setriline does. I highly recommend it. I also see that a majority of negative reviews are from younger people in school, so maybe it effects younger teenagers different. I’m 31 and it’s worked wonders for me!! People have talked about libido issues but for me it’s the opposite, constant tingling in the manhood and rearing to go night or day!! To be honest I would put a rabbit to shame while on setraline. Read More Read Less

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Fill 3Created with Sketch. Condition: Extreme Apprehension or Fear of Social Interaction

Overall rating 4.3

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I honestly feel setraline changed my life. After taking it for about three months I began seeing an improvement on my anxiety. I didn’t feel socially awkward, my neck and head stopped twitching in front of a crowd. I lost the need to constantly masturbate. I could socialize more. I kinda split my pill in two though. The 100mg. I think setraline is good for social anxiety and OCD. However, I do get tummy issues. If not ache or nausea then its constipation. I’m happy with setraline. Now I do not care so much about what others think of me or what I’m doing in the momentRead More Read Less

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5 Stars

Posted 1 months ago (5/26/2023) 5

Rated for Premature ejaculation Report

I have had lifelong premature ejaculation and tried the usual techniques – numbing gel, start-stop technique etc. all of which offered only minor help. I happened to read about doctors prescribing low does SSRIs for PE so I mustered the courage to ask my doctor. She was supportive and tried me on low dose Paxil which worked well but the gastro-intestinal and headache side effects were nasty. She then switched me to 50 mg Zoloft which was as bad. Finally I asked her – why not 25 mg Zoloft? This was the sweet spot – very minor headaches and GI issues that went away within a couple weeks. Yes there are the usual sexual side effects – but a decreased libido is not the end of the world – at 25 mg there is still sufficient libido and while there is less frequency I last much longer and satisfy my wife fir the first time in our marriage. Essentially I have traded daily masturbation for sex a couple times a month and at age 60 that suits both of us very well. I encourage you to try but at the 25 mg dose. After being on it a while and doing well, you could always try 50 mg if you need to last even longer.

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4 Stars

Posted 1 months ago (5/10/2023) 4

Rated for Generalized anxiety disorder (GAD) Report

Was diagnosed with anxiety, took sertraline and after a few weeks of mild symptoms like lightheaded, hot flushes, heart racing etc for short periods here and there, the drug started to work. Repetetive negative thoughts subsided however I lost interest in sex and it just felt weird, though still functional, it felt clinical as my mind was not able to be flooded with seratonin so there was no pleasure, also was not able to feel my partners pleasure so had trouble sharing the experience. Ended up with a spine injury work related and took pain meds that made me feel overwelmed with chemicals so stopped sertraline, 4 days later, symptoms were gone, sexual feelings returned but so did negative thoughts. Seeing doctor again to try CBT or some other non drug related therapy before going back on sertraline. Drug seems to work well but treating the root cause which in my case is tired of abusive people and can no longer handle them in the slightest… which makes life hell because they are everywhere… prettt sure I have PTSD so will probably end up back on sertraline. At least there is something that can releive the symptoms of anxiety. Wish you all the best, spend time with this who care

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1 Stars

Posted 2 months ago (4/26/2023) 1

Rated for Obsessive Compulsive Disorder Report

Horrible side effects including shrunken penis and testicles. 300 lb.3 weight gain in 6 months was skinny prior to use now obese loss of life direction or any want to achieve anything

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1 Stars

Posted 3 months ago (3/19/2023) 1

Rated for Depression Report

I have taken this drug for a month now and it makes me feel so fatigued all day long plus I can not sleep at night and wake up at least 10 times a night I am gone stop taking this medicine as of today. It has not helped my depression or anxiety at all. Terrible medcine

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4 Stars

Posted 3 months ago (3/12/2023) 4

Rated for Depression Report

Suffered depression for 25 years so finally decided to try a pharmacological solution. Was not expecting it to work. It didn’t. Side effects were horrific for a couple of days then abated. After 1 month nothing. GP upped me to 100mg. Side effects horrific for a couple of days. Another 6 weeks, still depressed. GP upped the dose to 150mg. Once again, horrible side effects for a few days. Then 2 weeks later I felt normal for the first time in years. I couldn’t believe it. No longer do I wake first thing in the morning depressed. I never expected it to work and for a long time it didn’t, until it did. I worry that it’ll one day stop working and I won’t find another solution. You have to bare out the side effects unfortunately.

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1 Stars

Posted 4 months ago (2/26/2023) 1

Rated for Depression Report

This is the worst drug ever made . .Avoid

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5 Stars

Posted 4 months ago (2/15/2023) 5

Rated for Chronic fatigue syndrome (CFS; CFIDS; M.E.) Report

Works very well and has helped me start to overcome my depression, but my God, do not dare ask for a larger tablet than 100mg. What do 200mg tablets take to make, dinosaur blood? Woolly mammoth bones? Or maybe they can only be synthesized in the belly of a volcano? Absolutely insane prices if you reach that point.

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4 Stars

Posted 4 months ago (2/5/2023) 4

Rated for Generalized anxiety disorder (GAD) Report

This pill saved my life. Before I started taking Zoloft- I was a very on edge person and drank to be outgoing and fun! I had depression and anxiety- anger bursts and no sense of direction. PLEASE remember- the side effects can last weeks to a month/possibly 2. Start off on a low dose (25mg or under, and work your way up every 4 weeks from there). The side effects are horrible at the start, but they go away.. That’s when the magic happens. Give the drug time to work- I am so lucky I stuck it out, as almost stopped 4 weeks in. I no longer have anxiety, I’m calm and enjoying life.

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5 Stars

Posted 4 months ago (1/29/2023) 5

Rated for Generalized anxiety disorder (GAD) Report

This drug is absolutely fantastic. I feel like I used to when I was younger. I cannot believe how a 50mg tablet can have stopped all my anxiety and depression. I wish I had taken it years ago. It seems to be having even better affects now after 4 months even though I actually noticed my mood lifting on the second day. Give it a chance, it could save your life and make you feel amazing, but in a natural way, like the you that has been there all the time, just burdened with anxiety and depression. I am so thankful that this wonder drug exists. I have no side effects. Just very mild ones the first week.

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4 Stars

Posted 5 months ago (1/6/2023) 4

Rated for Premenstrual Syndrome Report

I began taking Zoloft after a few rough months of PMDD after stopping brith control. I was having mass amounts of anxiety that caused a lot of physical and mental instability. Although I have strong belief in natural healing and finding the root cause of an issue rather than masking it with prescriptions, my doctor recommended this to me short term so I could function at work without having a high amount of anxiety during the two weeks before Mother Nature came for a visit. After about a month of uneasy side effects, I will say this worked really well for me (my mom and sister both take it as well, so genetically speaking, it that may be why). HOWEVER, the side effects were rough… I developed a bit of “depression” which has never been an issue for me causing a lot of uncontrollable constant crying for no reason. The heartburn/acid reflux this gave me for the few weeks was indescribably intense. Not to mention the overwhelming migraines it gave me for about two weeks. So as uncomfortable as the side effects were, there was light at the end of the tunnel. The side effects wore off and I felt like myself again.

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5 Stars

Posted 6 months ago (12/2/2022) 5

Rated for Obsessive Compulsive Disorder Report

I suffered from severe OCD for 10 years. The psychiatrist recommended Paxil but it didn’t work. He switched me to Zoloft and I got heat rash, night sweats, and diarrhea. My OCD kicked into high gear and convinced me that I got AIDS from riding the bus. I stayed on Zoloft and after a month I felt better. 5 years later and I feel terrific. The side effects are gone and life is great – I have also been promoted 3 times in the last 3 years to a Senior Vice President because I am firing on all cylinders and I am no longer depressing to be around. I have put on 30 lbs, but that’s because I have been enjoying my life a little too much now. Good luck!

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1 Stars

Posted 7 months ago (11/10/2022) 1

Rated for Anxiety Report

I had the most horrible side effects i first started on 25mg for a week and then went up to 50mg a week it was the worst thing i could have done it’s made me have suicidal ideation, i feel numb like i have no emotions, I’m always angry & snappy, i don’t find interest in anything anymore I’m now trying tms therapy and have stopped taking sertraline i was on it for 3weeks and it turned me into a different person i feel like I’m just living in a shell.

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5 Stars

Posted 8 months ago (10/15/2022) 5

Rated for Depression Report

Has changed my life completely. The side effect initially were bad but after 2 weeks it worked wonders.

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1 Stars

Posted 8 months ago (10/15/2022) 1

Rated for Depression Report

Zoloft was probably the most horrific antidepressant I’ve ever taken and I’ve tried many. The severe side effects didn’t start until 7 weeks in, I had 2 severe panic attacks, derealization, insane thoughts, and obsessive thoughts, shaking, feeling like I was losing my mind, obsessive researching and just obsessive behavior, pacing, memory issues.

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5 Stars

Posted 8 months ago (10/1/2022) 5

Rated for Generalized anxiety disorder (GAD) Report

I have now been on sertraline twice. I took it in 2020 when I opened my business. My anxiety and paranoia was severe. I would cry and panic pretty well on a daily. It took about 12 weeks for me to feel normal. It works with time. I stopped taking it in Jan 2022. Mistake. Over the last 8 months my anxiety and paranoia came back. Lots of life stress triggered it. I’ve been back on 25mg of sertraline for 3 weeks now. The side effects are exactly the same as 2 years ago. It makes anxiety worse for a bout 4-5 days, I lose my appetite (drink ensure, it’s easier than solids), GI disturbances, and trouble sleeping at first. That goes away. I take it at night because it makes me drowsy. Starting week 4 and intrusive thoughts are happening and still morning anxiety. You have to be patient. This drug is inhibiting neurotransmitters in your brain. It takes time for the brain to adapt. Keep your support close, have a counsellor to talk to, and self care is key. Hang in there guys. It’s all going to be ok.

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1 Stars

Posted 10 months ago (8/17/2022) 1

Rated for Chronic fatigue syndrome (CFS; CFIDS; M.E.) Report

ZOLOFT 25mg, I will never take this drug again, all side effects and more, only took one dose and only one.. called dr office and they never even called me back.. the Axintey and panic was off the chain. No appetite. no drug is not for me

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1 Stars

Posted 10 months ago (8/16/2022) 1

Rated for Depression Report

Started taking Zoloft 7 days ago for anxiety/depression & will be stopping it myself tomorrow due to the HORRIBLE side effects. Nausea starting when I wake up and lasting all day (which has lead to me losing almost 10lbs), loss of appetite, fatigue, agitation, increased anxiety/depression & even thoughts of suicide that I’ve never had before. I know people who have never had side effects from this, but for me it has flipped my world upside. I feel agitated anytime I talk to people & have cried every single day, feeling like I’m unable to control it. It’s the lowest I’ve ever felt, and I wouldn’t recommend this drug to anyone.

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1 Stars

Posted 10 months ago (8/13/2022) 1

Rated for Chronic fatigue syndrome (CFS; CFIDS; M.E.) Report

Far too long , the cycle ends now. Hope you’ve made your profits. This offered very little benefit , it keeps you locked due to the side effects of coming off. I don’t trust half of these reviews either , try reviewing it years down the line instead ! SSRis should only be part of a well being program no longer than 6 months ! And doctors should provide equal help of coming off !

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1 Stars

Posted 11 months ago (7/12/2022) 1

Rated for Depression Report

worst 6 month for me

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5 Stars

Posted 12 months ago (6/17/2022) 5

Rated for Anxiety Report

I was quite apprehensive about anti-depressants ahead of taking it. I’m 23 years of age and thought, this is an incredibly early stage to start this. I’m glad that I pushed through that mindset. The first 1.5 weeks were tough, weird bodily sensations such as light headedness, acute awareness of everything and nervousness. After about a month my social anxiety was significantly reduced, I became a lot calmer and happier, less judgemental of myself. One thing they don’t tell you is that you sweat quite a bit, so water is your best friend ! My doctor described it as this, sertraline should be used whilst seeing a therapist, imagine youre on a boat on a stormy sea, far from land. Sertaline calms the ocean, counselling brings you back to land. You’re never too young for anti-depressants, believe in yourself, a lot of people can relate:) Hope this helps!

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1 Stars

Posted 12 months ago (6/3/2022) 1

Rated for Generalized anxiety disorder (GAD) Report

I started at 25mg and within hours I felt sick, confused, disoriented. I was having extreme chills, and then too hot. I was terribly nauseous, became much more anxious. I could not sleep, and I felt depressed and suicidal. My psychiatrist pushed this drug hard against my better judgement. I should have listened to myself. Terrible drug. I still don’t feel right after 24 hours or more.

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2 Stars

Posted 13 months ago (5/10/2022) 2

Rated for Post-Traumatic stress disorder (PTSD) Report

I am 5.5 weeks in on Zoloft (50mg) and I am miserable. I was on a very effective dose of Cymbalta, but was requested to wean off of it due to increased chance of hemorrhage with a c-section. I was content and doing very well on Cymbalta through all 6 months of pregnancy, and since being on Zoloft I have had nothing but night time anxiety, severely low self esteem, I sleep an upward of 14 hours a day, and I have constant suicidal ideation. If it was not for the fact that I have kids and I would feel selfish, this medication change would likely drive me to suicide. I am considering upping the dosage, but truthfully I do not see this medication being any benefit to me.

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1 Stars

Posted 13 months ago (5/2/2022) 1

Rated for Depression Report

Within 2 days I was hospitalised with a nervous break down. This drug made me ten times worse. 30 plus panic attacks through the night waking constantly thinking I was going to die. I’ve never felt so awful in my life. Be careful.

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5 Stars

Posted 13 months ago (4/30/2022) 5

Rated for Panic disorder / agoraphobia Report

I told my self that I would share my experience if Sertraline (Zoloft) helped me, so here I am. I’m a healthy young man, with a fantastic life. Got a job I love, kids and a wife I adore. I have no obvious reason to struggle with my mental health, yet I somehow developed intense panic disorder. I would wake up all night and be shaking, my muscles twitch and tic, I had constant diarrhea, and a feeling of intense dread and despair 24 hours a day. Sertraline made all of that go away almost entirely! The first 2 weeks were very hard. Everything got worse but by day 10 I could feel it starting to work, and my panic attacks beginning to go away. By day 15 I was sleeping through the night and by week 3 I was great, with no side effects. It felt like I had been connected to a torture machine for the brain and then someone turning it down and then turning it off. My thoughts are clear and I’ve stopped worrying all the time. I think I might have OCD and that’s also gone. I love sertraline!

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1 Stars

Posted 14 months ago (4/12/2022) 1

Rated for Anxiety Report

I have tried so many things that I’m desperate to find something that works. It’s not this pill. 3 weeks info it and the whole time I’ve been having side effects. Night sweats, headaches, dizziness, brain fog and brain. It’s causing my anxiety go go up. I can’t live like this anymore

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1 Stars

Posted 14 months ago (4/7/2022) 1

Rated for Panic disorder / agoraphobia Report

One 50g dose… within 3 hours started having nerve pain in my forearms like burning on the inside. Then came severe drowsiness, anxiety, dissociation (never experienced that before), VERY dark crazy violent thoughts, suicidal ideation, bad diarrhea, tremors, stomach cramps, confusion, weakness, felt like I wanted to die. I have been on many SSRIs/SNRIs over the years and NEVER had this severe a reaction from the get-go! The next day was slightly better, but I started having tachycardia (not like a panic attack) and had to take ativan and propanolol just to calm it down. It felt like my blood was buzzing or boiling. Thank goodness I had some of those on hand. I would have ended up in the ER. It was pretty frightening overall. I contacted my new provider who had prescribed it and the nurse on phone chuckled and told me it couldn’t possibly be from the Zoloft! She was very condescending. 4 days later I still feel foggy, but really, it was a nightmare. One dose! I had a telehealth appt. with the prescriber today and was going to ask for a different med. Instead they told me I needed to go inpatient and they would no longer keep me as a patient! After one appointment! Obviously

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1 Stars

Posted 14 months ago (4/3/2022) 1

Rated for Panic Disorder Report

Zoloft caused the worst panic attack I have ever had in my life! My heart was racing so much I could feel it in my arms and shoulders. The inside of my body was on fire. It was like waves of fire going through my body. I was pacing and legit thought I was going to die. I almost called ambulance. This was 10x worse than any panic attack I have experienced. My mouth was also extremely dry and I was yawning and extremely nauseous. It felt like I was outside of my body. It took me 2 hours to get back to my baseline after this. I have now been in bed since.

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1 Stars

Posted 15 months ago (3/24/2022) 1

Rated for Anxiety Report

I wouldn’t recommend this at all I was taking a low dose for 3 weeks it had my heart pounding my body weak heart palpitations and it had my brain feeling super wierd I stop taking it last Friday and the withdrawal feels nutty don’t take it if anything benadryl or Xanax but your doctor won’t give you Xanax unless you rich I guess smh

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1 Stars

Posted 15 months ago (3/9/2022) 1

Rated for Anxiety Report

Let me tell you be very careful this stuff is not good what so ever it causes suicidal thoughts I remember I took 1 25mg I went to the hotel tht night with family my family decided to go swimming if I wasn’t strong minded enough I would’ve jumped in the water and drowned this stuff make u very suicidal and panic attacks were horrible ??????I ended up in a mental hospital had to be away from my kids tryin to fix one problem tht wasn’t sooo bad ended up really bad could’ve lost my life please please be careful and be strong enough to get help if u have any bad thoughts ??

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2 Stars

Posted 15 months ago (3/5/2022) 2

Rated for Anxiety Report

Started at 25mg. Day one took at bedtime and just felt sleepy which was great. Next day had headache, ears ringing, dizziness. Took 25mg 2nd night. Felt like tingling all over, racing thoughts, dry mouth, headache, anxious. My chief issue is health anxiety and I just could not handle even 2 days with side effects that caused more health issues to worry about. Glad it works for some but not me. Didn’t get chance to see if would help anxiety.

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5 Stars

Posted 15 months ago (3/1/2022) 5

Rated for Post-Traumatic stress disorder (PTSD) Report

I’ve had my ups and downs with this medicine it helps my depression, ptsd and anxiety attacks but the side effects be tough like loss of appetite and sweating but you can override the loss of appetite by taking protein

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2 Stars

Posted 16 months ago (2/19/2022) 2

Rated for Generalized anxiety disorder (GAD) Report

I have anxiety, depression, and ptsd. I felt better at first taking Zoloft- but honestly the constant hunger and weight and complete lack of sexual appetite, I dropped down to 25 MG. Now it’s not doing anything for me. I’ll be switching meds asap.

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5 Stars

Posted 16 months ago (2/12/2022) 5

Rated for Panic disorder / agoraphobia Report

The first two weeks on this medicine was horrible. I was pulled into the office at work because they wanted to know what was wrong with me. It was like I was there but not there. Week 3 I started feeling better. I was prescribed 200mg but I felt horrible when I took it so I dropped down to 100mg and I feel so much better.

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5 Stars

Posted 16 months ago (2/6/2022) 5

Rated for Depression Report

I was put on this medicine , starting dose of 25 MG. Now I take 200 MG once a day. Been on Zoloft for 24 years and I am doing well. I feel the difference when I stop taking it for a few days.

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1 Stars

Posted 16 months ago (2/1/2022) 1

Rated for Post-Traumatic stress disorder (PTSD) Report

bad, make my trauma obsessive thoughts worse, auditory hallucinations and my feeling of constant on guardness got worse, i dont suggest this med EVER

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Zoloft…lost 3.5 kg in a week

Zoloft…lost weight in …

October 15, 2020, 09:03

December 02, 2022, 04:30 PM Go to

October 15, 2020, 09:07

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October 15, 2020, 09:46 9000 3

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Who had this? Tell me please, I drink from cancerophobia, and then I also lost weight, covers . ..

October 17, 2020, 09:36

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Please tell me, I drink from cancerophobia, and then I also lost weight, it covers …

October 20, 2020, 21:47 Lost 7 kg. Probably, this is such a side effect and you don’t want to eat at all.

02 May 2021, 08:44

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19 responses

Zoloft – drug reviews from 49patients after treatment I read the instructions for Zoloft, my hair stood on end from the described side effects, I didn’t want to try right away.

A.K., November 1, 2013

spasibo. Nastoiashii otziv. Propalo zgelanie probovat. Thanks.

Lana Del Rey, October 31, 2013

I had a difficult period in my life. Everything collapsed at once, sad events in my personal life, problems at work, health problems intensified on a nervous basis. I was in despair, at first it seemed that I was just very tired, and I had to change everything, change the situation and survive. But several months passed, during the day she could still be distracted by work, and going to bed, she cried all the time, remembering what had happened. I realized that such a state would not bring any benefit, it was getting worse. Biotredin has long been seen in a pharmacy, it was written that it improves mood. Bought and decided to drink. Before that, she could not sleep normally at night, she cried. After I started taking it, I began to literally pass out, like clockwork. With the help of him, she was able to survive all the unpleasant moments.

irina fedorenko, October 23, 2013

It was about 16 years ago. I had a low mood, phobias, a psychiatrist in the regiment prescribed a new advertised drug Zoloft, it had just entered our market. She praised him very much. I read the instructions, there were no side effects at all, except for positive ones, were described. So, on the 1st day after taking (after 2 hours), I felt some strange, rapidly growing fear that was difficult to control (before that, no there was no fear). The pupils are dilated. With difficulty I survived until the next day and went to the doctor. She-it can’t be, it’s your personal condition. I, as an obedient patient, drink a pill on the 2nd day – everything is the same, only 2 times worse. Where was my logic, when I drank the drug and on the 3rd day, it is not clear. This is where it STARTED! Fear and horror grew, became almost uncontrollable. The pace has risen. 38.5 The skin burned unbearably all over the body. Vomiting began, pressure rose, although it is usually low. With my neurosis, I have never experienced such horror and fear before. My husband was scared and didn’t know what to do. I started screaming and literally rolling on the carpet. I ran to the open window shouting “Help” and a great desire to jump from the 5th floor. The husband’s parents took the child to another room so that he would not see this nightmare. The whole body was trembling, terribly feverish. The half-life of the tablet was long. I understood that if I called an ambulance, they would not be taken to therapy, but to a psycho, where they would decide that this was my personal condition, they would inject me with chlorpromazine and … How it all ends, it could already be threateningly dangerous. A friend of my husband advised me to find everything soothing in the house. 2 old tablets of phenazepam were stuffed into my mouth, the 3rd in an hour. After 2 hours, somehow I began to understand something, the temperature and pressure were dropping. I felt bad for another week after I stopped taking it. Dear friends, psychiatrists do not test antidepressants on themselves! But I experienced serotonin syndrome, as explained to me much later. Terrible and dangerous condition. People, be careful!!! Especially with the new serotonin reuptake inhibitor drugs! It is they who can give such dangerous conditions. If it became clearly ill after the 1st tablet, do not drink the second. The drug accumulates, the condition can become severe.

Svetlana &, October 18, 2013

helps well from the second week

Eva Nerobkaya, October 9, 2013

Good afternoon! I can’t say enough good things about this drug! The shock takes from the list of side effects! How can doctors even prescribe it? At the same time, saying that in general it is possible for almost small children !!! I drank one package, the result is not special, it calms, but a lot of BUT! Dear readers, before taking, read the side effects! I agree it causes headaches and nausea! But the saddest thing in my practice is the onset of alopecia, after it! Now a lot of money is spent on hair treatment, it affects the hair, causes hair loss and is very plentiful! Or, if you are still determined to take it, donate blood and urine for biochemistry before taking such risks! I don’t understand how such a drug can be produced with such a huge number of adverse reactions! And the doctors prescribing them must be fully aware of your health condition before advising it! Be careful! Be healthy!

NATALYA LOGUNOVA, October 5, 2013

Appointed to the granddaughter.