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Side effect of yellow fever vaccine: Reactions to Yellow Fever Vaccine

Yellow Fever Vaccine Information Statement

Current Edition Date: 4/1/2020

  • Print VIS [2 pages]
  • RTF file [4 pages]
    (For use in electronic systems)
  • VIS in other languages
  • More information about yellow fever vaccination
  • Why get vaccinated?
  • Yellow fever vaccine
  • Talk with your health care provider
  • Risks of a vaccine reaction
  • What if there is a serious problem?
  • How can I learn more?

Yellow fever vaccine can prevent yellow fever. Yellow fever is a serious disease caused by the yellow fever virus. There is no medicine to treat or cure yellow fever.

Yellow fever virus is spread by the bite of an infected mosquito. It is found in parts of Africa and South America.

The majority of people with yellow fever virus infections will either not have symptoms, or have mild disease and completely recover. But some people will develop severe disease.

Symptoms and signs of yellow fever include:

  • Sudden onset of fever and chills
  • Headache, back pain, or general body aches
  • Nausea or vomiting

More severe symptoms of yellow fever can include:

  • Jaundice (yellow skin or eyes)
  • Bleeding from multiple body sites
  • Shock (life-threatening condition in which the body is not getting enough blood flow)
  • Liver, kidney, or other organ failure

Severe yellow fever can cause death in 30% to 60% of affected people.

In addition to getting vaccinated, you can also protect yourself from yellow fever by avoiding mosquito bites:

  • Use insect repellent
  • Wear long-sleeved shirts and long pants
  • Stay in well-screened or air-conditioned areas

Yellow fever vaccine is a live vaccine containing weakened, live yellow fever virus. It is given as a single shot. One dose provides lifelong protection for most people.

Yellow fever vaccine is recommended for:

  • People 9 months through 59 years of age who are traveling to or living in areas at risk for yellow fever virus activity, or traveling to a country with an entry requirement for vaccination. (People younger than 9 months or older than 59 years who are at increased risk might receive yellow fever vaccine in some situations. Ask your health care provider for more information.)
  • Laboratory personnel who might be exposed to yellow fever virus or vaccine virus.

Yellow fever vaccine is given only at designated vaccination centers. After getting the vaccine, you will be given an “International Certificate of Vaccination or Prophylaxis” (ICVP, sometimes called the “yellow card”). You will need this card as proof of vaccination to enter certain countries. If you don’t have it, you might be required to get yellow fever vaccine upon entering the country, or be forced to wait for up to 6 days to make sure you are not infected.

Do not donate blood for 14 days after vaccination, because there is a risk of passing vaccine virus to others during that period.

Discuss your itinerary with your health care provider before you get your yellow fever vaccination. You can visit CDC’s Travelers’ Health website at https://wwwnc.cdc.gov/travel to learn if yellow fever vaccination is recommended or required based on your travel location.

Tell your vaccine provider if the person getting the vaccine:

  • Has had an allergic reaction after a previous dose of yellow fever vaccine, or has any severe, life-threatening allergies.
  • Has a weakened immune system.
  • Has had their thymus removed or been diagnosed with a thymus disorder.
  • Is pregnant or
  • Has gotten any other vaccines in the past 4 weeks.

People with minor illnesses, such as a cold, may be vaccinated. People who are moderately or severely ill should usually wait until they recover before getting yellow fever vaccine.

In some cases, your health care provider may decide to postpone yellow fever vaccination to a future visit.

If you cannot get yellow fever vaccine for medical reasons and you are traveling to a country with a yellow fever vaccination entry requirement, your doctor will need to fill out the Medical Contraindications to Vaccination section of your yellow card. In addition, your doctor should give you a waiver letter. If you plan to use a waiver, you can contact the embassies of countries you plan to visit for more information.

  • Soreness, redness, or swelling where the shot was given are common after yellow fever vaccine.
  • Fever sometimes happens.
  • Headache and muscle aches can occur.
  • More serious reactions happen rarely after yellow fever vaccine. These can include:
    • Nervous system reactions such as inflammation of the brain (encephalitis) and/or spinal cord covering (meningitis), or Guillain-Barré Syndrome (GBS), among others.
    • Life-threatening severe illness with organ dysfunction or failure.

People 60 years and older and people with weakened immune systems might be more likely to experience serious reactions to yellow fever vaccine.

People sometimes faint after medical procedures, including vaccination. Tell your provider if you feel dizzy or have vision changes or ringing in the ears.

As with any medicine, there is a remote chance of a vaccine causing a severe allergic reaction, other serious injury, or death.

An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital.

For other signs that concern you, call your health care provider.

Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself. Visit the VAERS website or call 1-800-822-7967VAERS is only for reporting reactions, and VAERS staff do not give medical advice.

  • Ask your health care provider.
  • Call your local or state health department.
  • Contact the Centers for Disease Control and Prevention (CDC):
    • Call 1-800-232-4636 (1-800-CDC-INFO) or
    • Visit CDC’s Yellow Fever website

Many Vaccine Information Statements are available in español and other languages. See https://www.immunize.org/vis.

Vaccine Information Statement
Yellow Fever Vaccine (4/1/20)

Department of Health and Human Services
Centers for Disease Control and Prevention

Office Use Only

Top of Page

What to Expect After the Shot

What is the yellow fever vaccine?

Yellow fever is a potentially fatal disease caused by the yellow fever virus.

The virus is found in parts of South America and Africa. It’s spread through the bite of mosquitos infected with the virus. It’s not transmitted from person to person.

Some people with yellow fever only experience flu-like symptoms and recover completely after a short time. Others develop a more severe form of the infection that causes serious symptoms, such as:

  • high fever
  • vomiting
  • yellow skin (jaundice)

According to the Centers for Disease Control and Prevention (CDC), 30 to 60 percent of those who develop a severe case of yellow fever die.

There’s no cure for yellow fever, though some treatments can help to reduce symptoms. There’s also a yellow fever vaccine that protects people against the yellow fever virus.

We explain how the vaccine works, how it’s given, and its potential side effects.

The yellow fever vaccine causes your immune system to produce antibodies against the virus. It’s administered as a relatively painless injection.

If you’re in the United States and are planning to travel to an area where yellow fever is common, you’ll need to get vaccinated at an authorized yellow fever vaccination center.

You can find their locations here.

Originally, a single dose was meant to last for at least 10 years. But in 2013, the World Health Organization (WHO) announced that a single injection should provide life-long immunity.

Keep in mind that this change still isn’t reflected in the International Health Regulations, a legally-binding document put out by WHO. As a result, some countries may not accept a certificate that’s more than 10 years old.

You can check regulations in specific countries here. You might want to call the local embassy before your trip just to be sure.

As with almost any other medicine or vaccine, some people have a reaction to the yellow fever vaccine.

Usually, this reaction is mild, with side effects such as:

  • fever
  • muscle aches
  • mild joint pain

In addition, any kind of injection can cause soreness, redness, or swelling around the injection site.

These side effects usually begin shortly after the injection and can last up to 14 days, though most resolve within one week. About 1 in 4 people who get the vaccine experience mild side effects.

There’s a small risk of serious side effects from the yellow fever vaccine. The CDC states that this includes:

  • a severe allergic reaction, which affects about 1 in 55,000 people
  • a severe nervous system reaction, which affects about 1 in 125,000 people
  • severe illness with organ failure, which affects about 1 in 250,000

After receiving the vaccine, keep an eye out for these symptoms of a serious allergic reaction:

  • behavior changes
  • hives
  • trouble breathing
  • high fever
  • swelling of the face, tongue, or throat
  • dizziness
  • weakness

Seek emergency treatment if you experience any of these within minutes or hours of getting the vaccine.

Other symptoms that warrant an immediate visit to a doctor include:

  • confusion
  • cough
  • difficulty swallowing
  • irritability
  • itching
  • nervousness
  • rapid heartbeat
  • rash
  • severe headache
  • stiff neck
  • throbbing in the ears
  • tingling
  • vomiting

Yellow fever vaccine is recommended for the following:

  • all persons aged 9 months or older who are living in or traveling to areas of South America, Africa, or other countries where the yellow fever virus is found
  • people who are traveling to countries requiring proof of yellow fever immunization
  • anyone who might come into contact with the yellow fever virus, such as laboratory workers or healthcare professionals

People who are pregnant are advised to get the vaccine only if they must travel to an area where there’s an epidemic and protection from mosquito bites isn’t possible.

The vaccine shouldn’t be given to:

  • children younger than 9 months of age
  • adults older than 59 years of age
  • people with reduced immunity, such as people with HIV or those receiving chemotherapy
  • people who’ve had a severe reaction to egg, gelatin, or other ingredients of the vaccine
  • people who’ve had a severe allergic reaction to a previous dose of the vaccine
  • people who’ve had their thymus removed or those with a thymus disorder
  • travelers over the age of 60 who haven’t been previously vaccinated against yellow fever

If you have a fever, it’s best to wait to get the vaccine until you’re feeling better.

In addition, those who are pregnant or breastfeeding should only be vaccinated if there’s an unavoidable risk or protection against mosquito bites isn’t possible.

Yellow fever is a serious illness, so it’s important to get vaccinated if you plan to be in an area where the virus is common.

If you’re not sure if you should get the vaccine, talk to a doctor. They can help you weigh the benefits and risks.

Keep in mind that the vaccine isn’t foolproof. When traveling to areas with the yellow fever virus, it’s important to still protect yourself against mosquito bites by using nets, insect repellants, and protective clothing.

Try to stay indoors during peak times when mosquitos may bite to further lower your risk. Most species bite from dusk to dawn, but one species feeds during the daytime. Staying in air-conditioned rooms can lower your risk.

Vaccination against yellow fever in Zaporozhye

(098) 309 03 03

(099) 309 03 03

st. St. Nicholas, 53a st. Fanatskaya, 19 st. Dneprovskaya, 24

Zaporozhye. We work daily from 8:00.

(093) 309 03 03

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Online Declaration

Safe and affordable yellow fever vaccine “Stamaril” at St. Nicholas Clinic.

Yellow fever is a disease caused by a virus, which is characterized by a severe course with fever up to 39-40C, severe general condition, jaundice, increased risk of bleeding. The disease is spread by infected Aedes mosquitoes and is not transmitted from person to person. The yellow fever vaccine is the single most reliable way to protect yourself against the disease when traveling to tropical countries.

Indications and contraindications

Yellow fever vaccination is not mandatory in our country and is not part of the routine vaccination schedule. But people planning a trip to Africa, Asia, South America must definitely prevent this disease.

Yellow fever vaccine is recommended:

  • When traveling to countries endemic for yellow fever (their list is available on the website of the Ministry of Health of Ukraine)
  • For those who live in epidemically unfavorable conditions for this infection
  • When visiting countries requiring an International Yellow Fever Vaccination Certificate (list can also be found on the MoH website
  • Persons whose profession is associated with possible contact with this infectious pathology
  • Laboratory workers who interact with the vaccine during its production or work with cells of the pathogen

Like all vaccinations, yellow fever medicine has contraindications:

  • Strong allergic reaction to the previous administration of the drug
  • Chronic diseases in the aggravation stage, acute diseases
  • Pregnancy (but in regions with a flash of yellow fever, pregnant women
  • Pathology of immunity (HIV-status, malignant enemies, taking corticosteroids are carried out , cytostatics, congenital immunodeficiencies)
  • Severe allergy to egg protein (since it is one of the components of the drug)

Features of preparation for vaccination against yellow fever

It is very important to agree on the date of travel and vaccination: yellow fever vaccination is carried out no later than 10 days before departure. It is advisable to vaccinate for 1.5-2 weeks, so that the immunity has time to fully form. Some general rules are required before immunization:

  • Refrain from drinking alcohol 72 hours in advance
  • 3 days before vaccination, do not introduce new foods into the diet and avoid contact with known allergens (if any)

Recommendations after vaccination and possible side effects

After vaccination, it is recommended to adhere to the following rules:

  • Avoid crowds (walking in public places, visiting cinemas, etc.)
  • Do not visit swimming pools, gyms, saunas for 2-3 days
  • Avoid physical activity for 3-5 days
  • Give up alcohol for 10 days
  • Do not rub the injection site with a washcloth, soap or gel for 3-4 days (at the same time you can bathe under ordinary warm (not hot) water

Usually, after vaccination against yellow fever, a person feels well, but between 4 and 10 days after vaccination, the body may experience a reaction in the form of fever up to 38. 5 C, malaise, dizziness, headache and muscle pain. The duration of these symptoms is not more than 3 days. This is a completely normal reaction of the body to the vaccine, do not worry.

A slight reddening occurs at the injection site, slight pain may disturb – this is also a variant of the norm, the symptoms will disappear on their own within a few days. If the above recommendations are not followed and infection is introduced, the injection site may fester. More rare consequences of yellow fever vaccination are an anaphylactic reaction to the drug, urticaria.

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Vaccine “Stamaril” and its benefits

The French-made drug from the leading pharmaceutical company Sanofi Pasteur differs from similar drugs from other manufacturers and has a number of advantages:

  • The vaccine has passed all stages of research, has shown its effectiveness in clinical trials, and is actively used to immunize the population of the whole world
  • The drug is highly purified, has a minimum number of adverse reactions, is well tolerated
  • Immunity develops quickly (in 10-15 days) and lasts for life

Benefits of getting vaccinated at the St.

Nicholas Clinic

Looking for a place to get vaccinated against yellow fever in Zaporozhye? St. Nicholas Clinic is an ideal choice. We offer:

  • Affordable prices for our services, despite the fact that the quality of their provision is one of the best in the city and region
  • Vaccination data is entered in the international vaccination passport in English
  • Opportunity to be examined and consulted by specialists on the basis of the clinic before immunization
  • Highly qualified, smiling and friendly medical staff who know all the details of their work
  • Comfortable conditions for immunization, bright and cozy room

Facilities for visitors of St. Nicholas Clinic

Private parking

Payment by card

Online appointment

Pharmacy in the building

Own laboratory

Electronic medical record

Yellow fever vaccine live dry instructions for use: indications, contraindications, side effects – description Yellow fever vaccine, live, dry lyophilisate for preparation.

r-ra for s / c injection 0.5 ml / 1 dose: 1 ml, 2.5 ml or 5 ml amp. 5 or 10 pcs. complete with solvent (36250)

📜 Instructions for use Yellow fever vaccine live dry

💊 Composition of the drug Yellow fever vaccine live dry

✅ Use of the drug Yellow fever vaccine live dry

📅 Storage conditions Yellow fever vaccine live dry

⏳ Expiry date Yellow fever vaccine live dry

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Product description

Yellow fever vaccine live dry
(Yellow fever vaccine, live, dry)

Based on the approved prescribing information and prepared for the electronic edition of the Vidal 2013 handbook, last updated: 2019. 08.02

Marketing authorization holder:

Enterprise for the production of bacterial and viral preparations of the Institute of Poliomyelitis and Viral Encephalitis named after. M.P. Chumakov RAMS FSUE
(Russia)

ATX code:

J07BD51

(Measles virus in combination with mumps virus, live attenuated)

Active substance:
yellow fever vaccine
(yellow fever vaccine)

Group

Group name

Dosage form

Yellow fever vaccine live dry

Lyophilizate for preparation. r-ra for s / c injection 0. 5 ml / 1 dose: 1 ml, 2.5 ml or 5 ml amp. 5 or 10 pcs. complete with solvent

reg. No.: LS-000592
dated 28.09.09
– Indefinitely

Release form, packaging and composition
yellow fever vaccine live dry

Lyophilizate for solution for s.c. administration in the form of a porous mass in the form of a light pink tablet.

Excipients : lactose monohydrate 20 mg, sorbitol 10 mg, L-histidine 1.2 mg, L-alanine 0.7 mg.
Thinner: water for injection.

1 ml (2 doses) – ampoules (10) complete with diluent 1.25 ml – ampoules (10) in a separate carton – carton packs.
2.5 ml (5 doses) – ampoules (10) complete with diluent 3 ml – ampoules (10) in a separate carton – carton packs.
5 ml (10 doses) – ampoules (10) complete with diluent 6 ml – ampoules (10) in a separate carton – carton packs.

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