Side effects of atenolol 50 mg. Atenolol 50mg Side Effects: Understanding Common and Serious Reactions
What are the common side effects of atenolol 50mg. How can patients manage cold fingers and toes caused by atenolol. When should you seek immediate medical attention while taking atenolol. What are the signs of a serious allergic reaction to atenolol.
Common Side Effects of Atenolol: What to Expect
Atenolol, a beta-blocker medication commonly prescribed for various cardiovascular conditions, can cause side effects in some individuals. While many people experience no or only minor side effects, it’s essential to be aware of potential reactions. Common side effects of atenolol, occurring in more than 1 in 100 people, are typically mild and often improve as the body adjusts to the medication.
Drowsiness and Dizziness
Feeling sleepy, tired, or dizzy is a frequent side effect of atenolol. These symptoms usually subside as your body acclimates to the medication. To manage this side effect:
- Sit or lie down if you feel dizzy
- Avoid driving, cycling, or operating machinery until you feel better
- Limit alcohol consumption, as it may exacerbate dizziness
Cold Extremities
Cold fingers or toes are another common side effect of atenolol. This occurs due to the medication’s effect on blood vessels. To alleviate this discomfort:
- Warm your hands and feet under running water
- Massage and wiggle your fingers and toes to improve circulation
- Avoid smoking and caffeinated drinks, which can constrict blood vessels
- Wear warm socks and mittens
- Avoid tight watches or bracelets that may restrict blood flow
Gastrointestinal Side Effects and Management
Atenolol can sometimes cause gastrointestinal disturbances. Understanding these side effects and how to manage them can help improve your comfort while taking the medication.
Nausea and Vomiting
If you experience nausea or vomiting while taking atenolol:
- Stick to simple, bland meals
- Avoid rich or spicy foods
- Consider taking atenolol after a meal or snack
- Stay hydrated by drinking plenty of water or clear fluids
- Take small, frequent sips if vomiting occurs
Is dehydration a concern when experiencing vomiting as a side effect of atenolol? Yes, dehydration can be a risk. Watch for signs such as decreased urination or dark, strong-smelling urine. If these symptoms occur, increase fluid intake and consult your healthcare provider if the problem persists.
Diarrhea
For those experiencing diarrhea as a side effect:
- Increase fluid intake to prevent dehydration
- Monitor for signs of dehydration, such as decreased urination or dark urine
- Consult a pharmacist or doctor before taking any anti-diarrheal medications
Stomach Pain
If you develop stomach pain while taking atenolol:
- Rest and try to relax
- Eat and drink slowly
- Consider smaller, more frequent meals
- Apply a heat pad or covered hot water bottle to your stomach for relief
- Consult your healthcare provider if the pain is severe or persistent
Serious Side Effects: When to Seek Medical Attention
While rare, some individuals may experience serious side effects when taking atenolol. It’s crucial to recognize these symptoms and seek prompt medical attention when necessary.
Cardiovascular and Respiratory Concerns
Contact your doctor or seek immediate medical care if you experience:
- Shortness of breath with a worsening cough during exercise
- Swollen ankles or legs
- Irregular heartbeat
- Wheezing or chest tightening
These symptoms could indicate potential heart or lung problems and require prompt evaluation.
Liver-related Side Effects
Be vigilant for signs of liver problems, such as:
- Yellowing of the eyes or skin (jaundice)
- Pale stools
- Dark urine
These symptoms may be less noticeable on darker skin tones but should still be reported to your healthcare provider immediately.
Hematological Concerns
Unexplained bruising or increased bruising tendency could indicate low platelet counts (thrombocytopenia). If you notice these symptoms, consult your doctor promptly.
Emergency Situations: When to Call 999
Certain symptoms require immediate emergency attention. Call 999 or seek emergency care if you experience:
- Chest pain that persists for more than a few minutes
- New or worsening chest pain if you have a history of angina
These symptoms could indicate a heart attack and require immediate medical evaluation.
Recognizing and Responding to Allergic Reactions
Although rare, atenolol can cause serious allergic reactions (anaphylaxis) in some individuals. Knowing the signs of an allergic reaction and how to respond is crucial for patient safety.
Signs of a Serious Allergic Reaction
Call 999 or go to the nearest emergency department immediately if you experience:
- Skin rash, which may include itchy, red, swollen, blistered, or peeling skin
- Wheezing
- Tightness in the chest or throat
- Difficulty breathing or talking
- Swelling of the mouth, face, lips, tongue, or throat
These symptoms may indicate anaphylaxis, a severe allergic reaction requiring immediate medical treatment.
Monitoring and Reporting Side Effects
While this article covers many common and serious side effects of atenolol, it’s not exhaustive. Patients should familiarize themselves with the complete list of potential side effects provided in the medication leaflet.
The Importance of Reporting Side Effects
Can patients contribute to medication safety by reporting side effects? Absolutely. The Yellow Card safety scheme allows patients and healthcare professionals to report suspected side effects of medications. This reporting helps regulatory authorities monitor the safety of medicines and take action when necessary.
To report a suspected side effect:
- Visit the Yellow Card website
- Provide details about the medication and the side effect experienced
- Submit your report
Your report can contribute to the ongoing safety assessment of atenolol and other medications, potentially helping other patients in the future.
Managing Side Effects and Continuing Treatment
Experiencing side effects doesn’t necessarily mean you need to stop taking atenolol. Many side effects are temporary and improve as your body adjusts to the medication. However, it’s essential to communicate with your healthcare provider about any side effects you experience.
Strategies for Coping with Side Effects
- Keep a symptom diary to track the frequency and severity of side effects
- Implement the management strategies discussed for common side effects
- Don’t hesitate to contact your healthcare provider if side effects are bothersome or persistent
- Never stop taking atenolol abruptly without consulting your doctor, as this can lead to adverse effects
How should patients approach their doctor about side effects? Be honest and specific about your experiences. Describe the symptoms, when they occur, and how they affect your daily life. This information helps your doctor determine whether adjustments to your treatment plan are necessary.
Balancing Benefits and Risks of Atenolol Treatment
While side effects are a concern, it’s important to remember that atenolol is prescribed because its benefits are believed to outweigh the potential risks for most patients. Atenolol plays a crucial role in managing various cardiovascular conditions, including:
- High blood pressure (hypertension)
- Angina (chest pain)
- Irregular heartbeats (arrhythmias)
- Prevention of future heart attacks in those who have already experienced one
The Importance of Continued Treatment
Why is it crucial to continue taking atenolol as prescribed, even if you feel well? Atenolol helps manage chronic conditions that may not always have noticeable symptoms. Stopping the medication abruptly can lead to a rebound effect, potentially causing a rapid increase in blood pressure or heart rate, which can be dangerous.
If you’re concerned about side effects or the long-term use of atenolol, discuss these concerns with your healthcare provider. They can provide personalized advice and, if necessary, explore alternative treatment options that may be more suitable for your individual needs.
Lifestyle Considerations While Taking Atenolol
To maximize the benefits of atenolol and minimize side effects, consider the following lifestyle adjustments:
- Maintain a healthy diet low in sodium and rich in fruits, vegetables, and whole grains
- Engage in regular physical activity, as approved by your doctor
- Limit alcohol consumption, as it can interact with atenolol and exacerbate side effects
- Quit smoking, as it can counteract the beneficial effects of the medication on your cardiovascular system
- Monitor your blood pressure regularly at home, if recommended by your healthcare provider
By adopting these healthy habits, you can support the effectiveness of your atenolol treatment and potentially reduce the likelihood or severity of side effects.
Side effects of atenolol – NHS
Like all medicines, atenolol can cause side effects in some people, but many people have no side effects or only minor ones.
Side effects often improve as your body gets used to the medicine.
Common side effects
These common side effects of atenolol happen in more than 1 in 100 people. They’re usually mild and only last for a short time. There are things you can do to help cope with them:
Feeling sleepy, tired or dizzy
As your body gets used to atenolol, these side effects should wear off. If atenolol makes you feel dizzy, sit or lie down until you feel better. Do not drive, cycle or use tools or machinery until you feel better. Avoid alcohol as it will make you feel worse.
Cold fingers or toes
Put your hands or feet under warm running water, massage them and wiggle your fingers and toes. Do not smoke or have drinks with caffeine in, as this can make your blood vessels narrower and further restrict blood flow to your hands and feet. Try wearing mittens (they’re warmer than gloves) and warm socks. Do not wear tight watches or bracelets.
Feeling sick or being sick (nausea or vomiting)
Stick to simple meals and do not eat rich or spicy food. It might help to take your atenolol after a meal or snack.
Drink plenty of fluids, such as water or squash, to avoid dehydration. Take small, frequent sips if you’re being sick. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee.
Do not take any other medicines to treat vomiting without speaking to a pharmacist or doctor.
If you take contraceptive pills and you’re being sick, your contraception may not protect you from pregnancy. Check the pill packet to find out what to do.
Diarrhoea
Drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee.
Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
If you take contraceptive pills and you have severe diarrhoea for more than 24 hours, your contraception may not protect you from pregnancy. Check the pill packet to find out what to do.
Stomach pain
Try to rest and relax. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your stomach may also help.
If you are in a lot of pain, speak to your pharmacist or doctor.
If this advice does not help and you are bothered by any of these side effects, keep taking the medicine but tell your doctor or pharmacist.
Serious side effects
It happens rarely, but some people have serious side effects when taking atenolol.
Tell your doctor or contact 111 now if:
- you have shortness of breath with a cough that gets worse when you exercise (like walking up stairs), swollen ankles or legs, or an irregular heartbeat – these can be signs of heart problems
- you have shortness of breath, wheezing and tightening of your chest – these can be signs of lung problems
- the whites of your eyes turn yellow, or your skin turns yellow, although this may be less obvious on brown or black skin, or you have pale poo or dark pee – these can be signs of liver problems
- you get unexplained bruising, or you bruise more easily than usual – these can be signs of low numbers of platelets in your blood (thrombocytopenia)
Go to 111. nhs.uk or call 111.
Immediate action required: Call 999 now if:
- you get chest pain that does not stop after a few minutes, or is new or worse if you already have angina
Chest pain is a possible sign of a heart attack and needs to be checked out as soon as possible.
Serious allergic reaction
In rare cases, atenolol may cause a serious allergic reaction (anaphylaxis).
Immediate action required: Call 999 or go to A&E now if:
- you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
- you’re wheezing
- you get tightness in the chest or throat
- you have trouble breathing or talking
- your mouth, face, lips, tongue or throat start swelling
You could be having a serious allergic reaction and may need immediate treatment in hospital.
Other side effects
These are not all the side effects of atenolol. For a full list, see the leaflet inside your medicine packet.
Information:
You can report any suspected side effect using the Yellow Card safety scheme.
Visit Yellow Card for further information.
Page last reviewed: 5 April 2022
Next review due: 5 April 2025
Atenolol Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
Warnings:
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, your doctor may direct you to gradually decrease your dose over 1 to 2 weeks.
When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat.
Warnings:
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, your doctor may direct you to gradually decrease your dose over 1 to 2 weeks.
When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat.
… Show More
Uses
Atenolol is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used to treat chest pain (angina) and to improve survival after a heart attack.Atenolol belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart.
How to use Atenolol
See also Warning section.
Take this medication by mouth with or without food as directed by your doctor, usually 1 to 2 times daily.
Apple juice and orange juice may prevent your body from fully absorbing atenolol. It is best to avoid drinking apple/orange juice within 4 hours of taking atenolol, unless your doctor or pharmacist tells you otherwise.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
If this product is used for chest pain, it must be taken regularly to be effective. It should not be used to treat chest pain when it occurs. Use other medications (such as nitroglycerin placed under the tongue) to relieve chest pain as directed by your doctor.
It may take 1 to 2 weeks before you get the full benefit of this medication. Tell your doctor if your condition does not improve or if it worsens (for example, if your blood pressure readings remain high or increase, if your chest pain occurs more often).
Side Effects
See also Warning and Precautions sections.
Dizziness, lightheadedness, tiredness, and nausea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid tobacco use.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: new or worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), very slow heartbeat, severe dizziness, fainting, trouble breathing, blue fingers/toes, mental/mood changes (such as confusion, mood swings, depression).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking atenolol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain types of heart rhythm problems (such as slow heartbeat, second- or third-degree atrioventricular block), breathing problems (such as asthma, chronic bronchitis, emphysema), blood circulation problems (such as Raynaud’s disease, peripheral vascular disease), kidney disease, heart failure, serious allergic reactions including those needing treatment with epinephrine, a certain muscle disease (myasthenia gravis).
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This product may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). The risk is higher if you have diabetes, or are vomiting, fasting, or not eating regularly. Other symptoms of low blood sugar level, such as dizziness and sweating, are not affected by this drug.
If you have diabetes, this product may make it harder to control your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
Children may be at greater risk for low blood sugar (hypoglycemia) while using this drug, especially if they are vomiting or not eating regularly. To help prevent low blood sugar, make sure children eat regularly. If your child cannot eat regularly, is vomiting, or has symptoms of low blood sugar (such as sweating, shaking), tell the doctor right away.
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using atenolol. Atenolol may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Interactions
See also How To Use section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
A product that may interact with this drug is: fingolimod.
Some products have ingredients that could raise your heart rate or blood pressure or worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).
Does Atenolol interact with other drugs you are taking?
Enter your medication into the WebMD interaction checker
Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: very slow heartbeat, severe dizziness, severe weakness, fainting, trouble breathing.
Do not share this medication with others.
Lifestyle changes such as stress reduction programs, exercise and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.
Check your blood pressure and pulse (heart rate) regularly while taking this medication. Learn how to monitor your own blood pressure and pulse at home, and share the results with your doctor.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Images
atenolol 50 mg tablet
Color: whiteShape: roundImprint: ATN 50
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 50 mg tablet
Color: whiteShape: roundImprint: Z 66
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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Color: whiteShape: roundImprint: Z 65
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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Color: whiteShape: roundImprint: ATN 100
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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Color: whiteShape: roundImprint: D 23
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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Color: whiteShape: roundImprint: M 231
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 100 mg tablet
Color: whiteShape: roundImprint: TEVA 753
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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Color: whiteShape: roundImprint: TEVA 93 752
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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Color: whiteShape: roundImprint: TEVA 787
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 50 mg tablet
Color: whiteShape: roundImprint: TEVA 93 752
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 50 mg tablet
Color: whiteShape: roundImprint: 93 752
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 25 mg tablet
Color: whiteShape: roundImprint: 93 787
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 25 mg tablet
Color: whiteShape: roundImprint: TEVA 787
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
atenolol 50 mg tablet
Color: whiteShape: roundImprint: TEVA 93 752
This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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This medicine is a white, round, scored, film-coated, tablet imprinted with “ATN 50”.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Atenolol: instruction, price, analogues | Monfarm tablets
- Pharmacological properties
- Indications Atenolol
- Application of Atenolol
- Contraindications
- Side effects
- Storage conditions
- Diagnosis
- Recommended alternatives
- Trade names
atenolol (4-(2-hydroxy-3-isopropylaminopropoxy)phenylacetamide) belongs to the group of antiadrenergic drugs. It has a cardioselective b1 – adrenoblocking effect. It has a pronounced antianginal, hypotensive and antiarrhythmic effects. Reduces the automatism of the sinus node, heart rate, slows down AV conduction, reduces myocardial contractility and its need for oxygen. When used in medium therapeutic doses, it does not cause side effects characteristic of non-selective b-adrenoreceptor blockers (bronchospasm, heart failure, etc.).
Atenolol is slowly absorbed from the gastrointestinal tract. The maximum concentration of the drug in the blood serum is reached 2-4 hours after ingestion. The elimination half-life after oral administration is 6-9 hours; in patients with renal insufficiency may be longer. To a small extent (less than 10%) undergoes biotransformation in the liver.
treatment of hypertension, angina pectoris, sinus tachycardia, for the prevention of supraventricular tachyarrhythmias. The drug of choice for prescribing to patients with a tendency to bronchospasm and spasm of peripheral vessels (the degree of risk is much lower than when using non-selective blockers of b-adrenergic receptors).
by mouth before meals. Tablets are swallowed without chewing, washing down with a small amount of water. The dosing regimen is set individually.
In hypertension, the initial dose is 50 mg once a day. In case of insufficient severity of the hypotensive effect, the dose is gradually increased to 200 mg / day. With angina pectoris and cardiac arrhythmias, atenolol is prescribed in an initial dose of 50 mg 1 time per day; with insufficient severity of the effect, the dose is increased to 100-150 mg / day. The maximum daily dose is 200 mg.
If the renal excretory function is impaired, dose adjustment is necessary: with creatinine clearance below 35 ml / min, the dose of atenolol should be reduced by 50%, with clearance below 15 ml / min – by 75%.
Discontinuation of atenolol, as with other b-adrenergic blockers, should be gradual, as abrupt discontinuation of the drug may exacerbate anginal syndrome and myocardial ischemia in patients with coronary artery disease and reduce exercise tolerance.